[Objectives]To investigate the content and distribution of inorganic elements in Astragalus membranaceus sourced from various regions in Gansu Province.[Methods]28 batches of A.membranaceus samples were collected and ...[Objectives]To investigate the content and distribution of inorganic elements in Astragalus membranaceus sourced from various regions in Gansu Province.[Methods]28 batches of A.membranaceus samples were collected and subsequently digested using the Multiwave 7000 super microwave digestion system.The contents of aluminum(Al),barium(Ba),beryllium(Be),cobalt(Co),chromium(Cr),iron(Fe),gallium(Ga),magnesium(Mg),manganese(Mn),nickel(Ni),antimony(Sb),tin(Sn),strontium(Sr),titanium(Ti),thallium(Tl),vanadium(V),and zinc(Zn)were quantified utilizing a PerkinElmer 2000 inductively coupled plasma mass spectrometer.Principal component analysis was performed utilizing SPSS 25.0 to identify the distinctive characteristic elements of A.membranaceus.Additionally,systematic cluster analysis was conducted using these characteristic elements as variables to investigate the relationship between the primary inorganic elements and the geographical origin of A.membranaceus.[Results]17 inorganic elements were identified in A.membranaceus specimens collected from Gansu Province,with characteristic elements including Ba,Co,Fe,Ga,Mn,Zn,and Sn.The contents of inorganic elements in various sources of A.membranaceus exhibited significant variability and demonstrated distinct clustering characteristics.[Conclusions]A.membranaceus,originating from Gansu Province,exhibits a high content of inorganic elements.However,variations in ecological environments can lead to differences in the specific inorganic elements that are enriched.This study aims to provide a reference for the further development and application of A.membranaceus.展开更多
Traditional Chinese medicine(TCM)has played a significant role in the prevention and treatment of chronic heart failure(CHF).To study TCM diagnosis of CHF,a total of 278 Chinese clinical research articles on the study...Traditional Chinese medicine(TCM)has played a significant role in the prevention and treatment of chronic heart failure(CHF).To study TCM diagnosis of CHF,a total of 278 Chinese clinical research articles on the study of CHF syndromes in recent 40 years retrieved from Web of Science,Scopus,Pub Med,Embase,CNKI,Wanfang Data,Cq VIP,and Sino Med.According to cumulative frequency analysis,network analysis,and hierarchical cluster analysis,the study found the distribution of CHF syndromes was syndrome of qi deficiency with blood stasis,syndrome of qi and yin deficiency,syndrome of yang deficiency with water flooding,syndrome of heart blood stasis obstruction,syndrome of turbid phlegm,and syndrome of collapse due to primordial yang deficiency.The syndrome elements on location of illness were heart,kidney,lung,and spleen.The syndrome elements on nature of illness were qi deficiency,blood stasis,yang deficiency,yin deficiency,water retention,and turbid phlegm.These findings can provide reference to the research on diagnosis and treatment of CHF,and contribute to the study on syndrome standardization and objective research of TCM diagnosis.展开更多
The 13-node quadrilateral and 39-node hexahedral cubic serendipity elements produce nodally integrated positive-definite lumped heat capacity matrices in higher-order finite element analysis.However,these elements dis...The 13-node quadrilateral and 39-node hexahedral cubic serendipity elements produce nodally integrated positive-definite lumped heat capacity matrices in higher-order finite element analysis.However,these elements display severe convergence deterioration in explicit transient heat conduction analysis with lumped heat ca-pacity matrices.This convergence decay is due to the violation of variational integration consistency by the standard Galerkin formulation with lumped heat capacity matrices.This issue is resolved by introducing the boundary-enhanced Galerkin weak form that incorporates the elemental boundary contribution in the discrete finite element formulation.Subsequently,it is theoretically proven that a direct nodal integration identically fulfills the variational integration consistency in the context of the boundary-enhanced Galerkin weak form.The proposed variationally consistent nodal integration therefore enables optimal convergence for explicit transient heat conduction analysis with lumped heat capacity matrices.The efficacy of the proposed variationally con-sistent nodal integration formulation for the 13-node quadrilateral and 39-node hexahedral cubic elements is thoroughly demonstrated via numerical examples.展开更多
[Objective] This study aimed to investigate the trace elements in Rehman- nia glutinosa Libosch. by using principal component analysis and clustering analysis. [Method] Principal component analysis and clustering anal...[Objective] This study aimed to investigate the trace elements in Rehman- nia glutinosa Libosch. by using principal component analysis and clustering analysis. [Method] Principal component analysis and clustering analysis of R. glutinosa medicinal materials from different sources were conducted with contents of six trace elements as indices. [Result] The principal component analysis could comprehen- sively evaluate the quality of R. glutinosa samples with objective results which was consistent with the results of clustering analysis. [Conclusion] Principal component analysis and clustering analysis methods can be used for the quality evaluation of Chinese medicinal materials with multiple indices.展开更多
The high-temperature dissolution behavior of primary carbides in samples taken from GCr15 continuous-casting bloom was observed in-situ by confocal laser scanning microscopy.Equations were fitted to the dissolution ki...The high-temperature dissolution behavior of primary carbides in samples taken from GCr15 continuous-casting bloom was observed in-situ by confocal laser scanning microscopy.Equations were fitted to the dissolution kinetics of primary carbides during either heating or soaking.Dissolution of carbides proceeded in three stages(fast→slow→faster)as either temperature or holding time was increased.During the heating process and during the first and third stages of the soaking process,the original size of the carbides determined the steepness of the slope,but during the middle(“slow”)stage of the soaking process,the slope remained zero.The initial size of the carbides varied greatly,but their final dissolution temperature fell within the narrow range of 1210-1235℃,and the holding time remained within 50 min.Fractal analysis was used to study the morphological characteristics of small and medium-sized carbides during the dissolution process.According to changes in the fractal dimension before and after soaking,the carbides tended to evolve towards a more regular morphology.展开更多
Purpose–The brake pipe system was an essential braking component of the railway freight trains,but the existing E-type sealing rings had problems such as insufficient low-temperature resistance,poor heat stability an...Purpose–The brake pipe system was an essential braking component of the railway freight trains,but the existing E-type sealing rings had problems such as insufficient low-temperature resistance,poor heat stability and short service life.To address these issues,low-phenyl silicone rubber was prepared and tested,and the finite element analysis and experimental studies on the sealing performance of its sealing rings were carried out.Design/methodology/approach–The low-temperature resistance and thermal stability of the prepared lowphenyl silicone rubber were studied using low-temperature tensile testing,differential scanning calorimetry,dynamic thermomechanical analysis and thermogravimetric analysis.The sealing performance of the lowphenyl silicone rubber sealing ring was studied by using finite element analysis software abaqus and experiments.Findings–The prepared low-phenyl silicone rubber sealing ring possessed excellent low-temperature resistance and thermal stability.According to the finite element analysis results,the finish of the flange sealing surface and groove outer edge should be ensured,and extrusion damage should be avoided.The sealing rings were more susceptible to damage in high compression ratio and/or low-temperature environments.When the sealing effect was ensured,a small compression ratio should be selected,and rubbers with hardness and elasticity less affected by temperature should be selected.The prepared low-phenyl silicone rubber sealing ring had zero leakage at both room temperature(RT)and�508C.Originality/value–The innovation of this study is that it provides valuable data and experience for the future development of the sealing rings used in the brake pipe flange joints of the railway freight cars in China.展开更多
Total hip arthroplasty for adults with sequelae from childhood hip disorders poses significant challenges due to altered anatomy.The paper published by Oommen et al reviews the essential management strategies for thes...Total hip arthroplasty for adults with sequelae from childhood hip disorders poses significant challenges due to altered anatomy.The paper published by Oommen et al reviews the essential management strategies for these complex cases.This article explores the integration of finite element analysis(FEA)to enhance surgical precision and outcomes.FEA provides detailed biomechanical insights,aiding in preoperative planning,implant design,and surgical technique optimization.By simulating implant configurations and assessing bone quality,FEA helps in customizing implants and evaluating surgical techniques like subtrochanteric shortening osteotomy.Advanced imaging techniques,such as 3D printing,virtual reality,and augmented reality,further enhance total hip arthroplasty precision.Future research should focus on validating FEA models,developing patient-specific simulations,and promoting multidisciplinary collaboration.Integrating FEA and advanced technologies in total hip arthroplasty can improve functional outcomes,reduce complications,and enhance quality of life for patients with childhood hip disorder sequelae.展开更多
This article presents a micro-structure tensor enhanced elasto-plastic finite element(FE)method to address strength anisotropy in three-dimensional(3D)soil slope stability analysis.The gravity increase method(GIM)is e...This article presents a micro-structure tensor enhanced elasto-plastic finite element(FE)method to address strength anisotropy in three-dimensional(3D)soil slope stability analysis.The gravity increase method(GIM)is employed to analyze the stability of 3D anisotropic soil slopes.The accuracy of the proposed method is first verified against the data in the literature.We then simulate the 3D soil slope with a straight slope surface and the convex and concave slope surfaces with a 90turning corner to study the 3D effect on slope stability and the failure mechanism under anisotropy conditions.Based on our numerical results,the end effect significantly impacts the failure mechanism and safety factor.Anisotropy degree notably affects the safety factor,with higher degrees leading to deeper landslides.For concave slopes,they can be approximated by straight slopes with suitable boundary conditions to assess their stability.Furthermore,a case study of the Saint-Alban test embankment A in Quebec,Canada,is provided to demonstrate the applicability of the proposed FE model.展开更多
Design a precision electroplating mechanical structure for automobiles based on finite element analysis method and analyze its mechanical properties.Taking the automobile steering knuckle as the research object,ABAQUS...Design a precision electroplating mechanical structure for automobiles based on finite element analysis method and analyze its mechanical properties.Taking the automobile steering knuckle as the research object,ABAQUS parametric modeling technology is used to construct its three-dimensional geometric model,and geometric simplification is carried out.Two surface treatment processes,HK-35 zinc nickel alloy electroplating and pure zinc electroplating,were designed,and the influence of different coatings on the mechanical properties of steering knuckles was compared and analyzed through numerical simulation.At the same time,standard specimens were prepared for salt spray corrosion testing and scratch method combined strength testing to verify the numerical simulation results.The results showed that under emergency braking and composite working conditions,the peak Von Mises stress of the zinc nickel alloy coating was 119.85 MPa,which was lower than that of the pure zinc coating and the alkaline electroplated zinc layer.Its equivalent strain value was 652×10^(-6),which was lower than that of the pure zinc coating and the alkaline electroplated zinc layer.Experimental data confirms that zinc nickel alloy coatings exhibit significant advantages in stress distribution uniformity,strain performance,and load-bearing capacity in high stress zones.The salt spray corrosion test further indicates that the coating has superior corrosion resistance and coating substrate interface bonding strength,which can significantly improve the mechanical stability and long-term reliability of automotive precision electroplating mechanical structures.展开更多
Objective: To compare the stress distribution in the periodontal ligament under different orthodontic forces during canine distalization using long-arm brackets, and to determine the optimal force value for this devic...Objective: To compare the stress distribution in the periodontal ligament under different orthodontic forces during canine distalization using long-arm brackets, and to determine the optimal force value for this device in orthodontic treatment. Methods: A finite element model was constructed after extracting the mandibular first premolar, and a long-arm bracket with a traction height of 6 mm was placed on the labial side of the mandibular canine. Three working conditions of 50 g, 100 g, and 150 g were simulated, and the magnitude and distribution of von Mises stress in the periodontal ligament were compared for each condition. Results: The maximum von Mises stress in the periodontal ligament was 0.013281 MPa in the 50 g condition, 0.02536 MPa in the 100 g condition, and 0.035549 MPa in the 150 g condition. As the orthodontic force increased, the stress distribution area in the periodontal ligament also expanded. Conclusion: A 100 g orthodontic force is the most suitable when using long-arm brackets, providing a relatively uniform stress distribution in the periodontal ligament and keeping the stress within a reasonable range.展开更多
To effectively address the challenge where the speed of tunnel lining construction struggles to match that of tunnel face and inverted arch construction,and to enhance the quality of secondary lining,a new type of ske...To effectively address the challenge where the speed of tunnel lining construction struggles to match that of tunnel face and inverted arch construction,and to enhance the quality of secondary lining,a new type of skeleton-free,traversing secondary lining trolley has been developed.This trolley features a set of gantries paired with two sets of formwork.The formwork adopts a multi-segment hinged and strengthened design,ensuring its own strength can meet the requirements of secondary lining concrete pouring without relying on the support of the gantries.When retracted,the formwork can be transported by the gantries through another set of formwork in the supporting state,enabling early formwork support,effectively accelerating the construction progress of the tunnel’s secondary lining,and extending the maintenance time of the secondary lining with the formwork.Finite element software modeling was used for simulation calculations,and the results indicate that the structural strength,stiffness,and other performance parameters of the new secondary lining trolley meet the design requirements,verifying the rationality of the design.展开更多
Due to their superior properties, the interest in nanostructures is increasing today in engineering. This study presents a new two-noded curved finite element for analyzing the in-plane static behaviors of curved nano...Due to their superior properties, the interest in nanostructures is increasing today in engineering. This study presents a new two-noded curved finite element for analyzing the in-plane static behaviors of curved nanobeams. Opposite to traditional curved finite elements developed by using approximate interpolation functions, the proposed curved finite element is developed by using exact analytical solutions. Although this approach was first introduced for analyzing the mechanical behaviors of macro-scale curved beams by adopting the local theory of elasticity, the exact analytical expressions used in this study were obtained from the solutions of governing equations that were expressed via the differential form of the nonlocal theory of elasticity. Therefore, the effects of shear strain and axial extension included in the analytical formulation are also inherited by the curved finite element developed here. The rigidity matrix and the consistent force vector are developed for a circular finite element. To demonstrate the applicability of the method, static analyses of various curved nanobeams subjected to different boundary conditions and loading scenarios are performed, and the obtained results are compared with the exact analytical ones. The presented study provides an accurate and low computational cost method for researchers to investigate the in-plane static behavior of curved nanobeams.展开更多
Identifying the damage and fracture properties of nuclear graphite materials and accurately simulating them are crucial when designing graphite core structures.To simulate the damage evolution and crack propagation of...Identifying the damage and fracture properties of nuclear graphite materials and accurately simulating them are crucial when designing graphite core structures.To simulate the damage evolution and crack propagation of graphite under stress in a finite element model,compression tests on disks and three-point bending tests on center-notched beams for fine-grained graphite(CDI-1D and IG11 graphite)were conducted.During these tests,digital image correlation and electronic speckle pattern interferometry techniques were utilized to observe the surface full-field displacements of the specimens.A segmented finite element inverse analysis method was developed to characterize the graphite’s damage evolution by quantifying the reduction in Young’s modulus with tensile and compressive strains in disk specimens.The fracture energy and bilinear tensile softening curve of the graphite were determined by comparing the load–displacement responses of the three-point bending tests and the finite element simulation.Finally,by combining the identified damage laws with a fracture criterion based on fracture energy,a damage–fracture model was established and used to simulate tensile tests on L-shaped specimens with different fillet radii.Simulations indicate that the damage area at the fillet expands with increasing radius,creating a blunting effect that enhances the load-bearing capacity of the specimens.This damage–fracture model can be applied to simulate graphite components in core structures.展开更多
The increasing occurrence of sinkholes caused by water main bursts has attracted significant research attention in recent years.This study addresses the gap in evaluating soil blowout stability resulting from water ma...The increasing occurrence of sinkholes caused by water main bursts has attracted significant research attention in recent years.This study addresses the gap in evaluating soil blowout stability resulting from water main failures by investigating the three-dimensional stability of blowouts with circular,hemispherical,and spherical openings.Advanced finite element limit analysis(FELA)combined with adaptive meshing is employed to analyze critical factors,including soil cover depth,surcharge pressure,and internal water pressure,that contribute to blowout failure.In addition,dimensionless ratios are used throughout the paper to assess the influence of these factors.Numerical findings are rigorously validated,ensuring reliability and accuracy.Practical design charts are provided to accommodate a wide range of design scenarios,offering valuable guidance for engineers.This study introduces a pioneering sinkhole simulation methodology,leading to the understanding of three-dimensional blowout stability mechanisms.展开更多
The incorporation of graphene fillers into polymer matrices has been recognized for its potential to enhance thermal conductivity,which is particularly beneficial for applications in thermal management.The uniformity ...The incorporation of graphene fillers into polymer matrices has been recognized for its potential to enhance thermal conductivity,which is particularly beneficial for applications in thermal management.The uniformity of graphene dispersion is pivotal to achieving optimal thermal conductivity,thereby directly influencing the effectiveness of thermal management,including the mitigation of local hot-spot temperatures.This research employs a quantitative approach to assess the distribution of graphene fillers within a PBX(plastic-bonded explosive)matrix,focusing specifically on the thermal management of hot spots.Through finite element method(FEM)simulations,we have explored the impact of graphene filler orientation,proximity to the central heat source,and spatial clustering on heat transfer.Our findings indicate that the strategic distribution of graphene fillers can create efficient thermal conduction channels,which significantly reduce the temperatures at local hot spots.In a model containing 0.336%graphene by volume,the central hot-spot temperature was reduced by approximately 60 K compared to a pure PBX material,under a heat flux of 600 W/m^(2).This study offers valuable insights into the optimization of the spatial arrangement of low-concentration graphene fillers,aiming to improve the thermal management capabilities of HMX-based PBX explosives.展开更多
Purpose–Type-120 relief valves are critical components of locomotive braking systems,and they rapidly discharge the air pressure during brake release to enable swift pressure relief.In order to develop type-120 relie...Purpose–Type-120 relief valves are critical components of locomotive braking systems,and they rapidly discharge the air pressure during brake release to enable swift pressure relief.In order to develop type-120 relief valve rubber diaphragms with long life and high performance,the damaged faulty samples were analyzed and studied.Design/methodology/approach–Finite element analysis(FEA)was used to investigate the stress distribution and failure mechanism of the rubber diaphragms within the type-120 relief valves under dynamic loading conditions.The Ogden hyperelastic constitutive model was used to fit the diaphragm data obtained from the uniaxial tensile tests,and its suitability for the modeling of large deformations was confirmed.Findings–The FEA results indicated that,when the rubber diaphragms reached their maximum deformation,the peak stress on their upper surfaces was 5.44 MPa.Thus,this region is highly susceptible to fatigue damage.The service life of the rubber diaphragms could be extended by using rubber compounds with high tensile moduli or a fabric-reinforced rubber diaphragm.Originality/value–This study provides valuable data and experience for the development of the rubber diaphragms in the type-120 valves and other long-life rubber products in the railway field.展开更多
Purpose–This paper aims to offer a novel viewpoint for improving performance and reliability by developing and optimizing suspension components in a Y25 bogie through material optimization based on wheel–rail intera...Purpose–This paper aims to offer a novel viewpoint for improving performance and reliability by developing and optimizing suspension components in a Y25 bogie through material optimization based on wheel–rail interactions under variable load and track conditions.Design/methodology/approach–The suspension system,a critical component ensuring adaptation to road and load conditions in all vehicle types,is especially vital in heavy freight and passenger trains.In this context,the suspension set of the Y25 bogie–commonly used in T€urkiye and Europe–was modelled using CATIAV5,and stress analyses have been performed by way of ANSYS using the finite element analysis(FEA)method.E300-520-M cast steel was selected for the bogie frame,while two different spring steels,61SiCr7 and 51CrV4,were considered for the suspension springs.The modeled system was subjected to numerical analysis under loading conditions.The resulting stresses and displacements were compared with the mechanical properties of the selected materials to validate the design.Findings–The results demonstrate that the mechanical strength and deformation characteristics of the suspension components vary according to the applied external loads.The stress and displacement responses of the system were found to be within the allowable limits of the selected materials,confirming the structural integrity and reliability of the design.The suspension set is deemed suitable for the prescribed material and environmental conditions,suggesting potential for practical application in real-world rail systems.Originality/value–This research contributes to the design and optimization of bogie suspension systems using advanced CAD/CAE tools.It thinks that the material selection and numerical validation approach presented here can guide future designs in heavy load rail applications and potentially improve both safety and performance.展开更多
Microstructure topology evolution during severe plastic deformation(SPD)is crucial for understanding and optimising the mechanical properties of metallic materials,though its prediction remains challenging.Herein,we c...Microstructure topology evolution during severe plastic deformation(SPD)is crucial for understanding and optimising the mechanical properties of metallic materials,though its prediction remains challenging.Herein,we combine discrete cell complexes(DCC),a fully discrete algebraic topology model-with finite element analysis(FEA)to simulate and analyse the microstructure topology of pure copper under SPD.Using DCC,we model the evolution of microstructure topology characterised by Betti numbers(β_(0),β_(1),β_(2))and Euler characteristic(χ).This captures key changes in GBNs and topological features within representative volume elements(RVEs)containing several hundred grains during SPD-induced recrystallisation.As SPD cycles increase,high-angle grain boundaries(HAGBs)progressively form.Topological analysis reveals an overall decrease in β_(0)values,indicating fewer isolated HAGB substructures,while β_(2) values show a steady upward trend,highlighting new grain formation.Leveraging DCC-derived RVE topology and FEA-generated plastic strain data,we directly simulate the evolution and spatial distribution of microstructure topology and HAGB fraction in a copper tube undergoing cyclic parallel tube channel angular pressing(PTCAP),a representative SPD technique.Within the tube,the HAGB fraction continuously increases with PTCAP cycles,reflecting the microstructure’s gradual transition from subgrains to fully-formed grains.Analysis of Betti number distribution and evolution reveals the microstructural reconstruction mechanism underpinning this subgrain to grain transition during PTCAP.We further demonstrate the significant influence of spatially non-uniform plastic strain distribution on microstructure reconstruction kinetics.This study demonstrates a feasible approach for simulating microstructure topology evolution of metals processed by cyclic SPD via the integration of DCC and FEA.展开更多
In this work, the finite element analysis of the elasto-plastic plate bending problems is carried out using transition rectangular plate elements. The shape functions of the transition plate elements are derived based...In this work, the finite element analysis of the elasto-plastic plate bending problems is carried out using transition rectangular plate elements. The shape functions of the transition plate elements are derived based on a practical rule. The transition plate elements are all quadrilateral and can be used to obtain efficient finite element models using minimum number of elements. The mesh convergence rates of the models including the transition elements are compared with the regular element models. To verify the developed elements, simple tests are demonstrated and various elasto-plastic problems are solved. Their results are compared with ANSYS results.展开更多
An element coupling model (ECM) method was proposed to simulate the global behavior and local damage of a structure.In order to reflect the local damage and improve the computational efficiency,three-dimensional (3D) ...An element coupling model (ECM) method was proposed to simulate the global behavior and local damage of a structure.In order to reflect the local damage and improve the computational efficiency,three-dimensional (3D) solid elements and one-dimensional (1D) beam element were coupled by the multi-point constraint equations.A reduced scale 1?8 model test was simulated by the ECM and a full three dimensional model (3DM) contrastively.The results show that the global behavior and local damages of ECM agree well with the test and 3DM.It is indicated that the proposed method can be used in the structural nonlinear analysis accurately and efficiently.展开更多
基金Supported by Project of NMPA Key Laboratory for Quality Control of Traditional Chinese Medicine(2023GSMPA-KL06,2024GSMPA-KL16).
文摘[Objectives]To investigate the content and distribution of inorganic elements in Astragalus membranaceus sourced from various regions in Gansu Province.[Methods]28 batches of A.membranaceus samples were collected and subsequently digested using the Multiwave 7000 super microwave digestion system.The contents of aluminum(Al),barium(Ba),beryllium(Be),cobalt(Co),chromium(Cr),iron(Fe),gallium(Ga),magnesium(Mg),manganese(Mn),nickel(Ni),antimony(Sb),tin(Sn),strontium(Sr),titanium(Ti),thallium(Tl),vanadium(V),and zinc(Zn)were quantified utilizing a PerkinElmer 2000 inductively coupled plasma mass spectrometer.Principal component analysis was performed utilizing SPSS 25.0 to identify the distinctive characteristic elements of A.membranaceus.Additionally,systematic cluster analysis was conducted using these characteristic elements as variables to investigate the relationship between the primary inorganic elements and the geographical origin of A.membranaceus.[Results]17 inorganic elements were identified in A.membranaceus specimens collected from Gansu Province,with characteristic elements including Ba,Co,Fe,Ga,Mn,Zn,and Sn.The contents of inorganic elements in various sources of A.membranaceus exhibited significant variability and demonstrated distinct clustering characteristics.[Conclusions]A.membranaceus,originating from Gansu Province,exhibits a high content of inorganic elements.However,variations in ecological environments can lead to differences in the specific inorganic elements that are enriched.This study aims to provide a reference for the further development and application of A.membranaceus.
基金financed by the grants from the National Natural Science Foundation of China(No.81803996)Shanghai Key Laboratory of Health Identification and Assessment(No.21DZ2271000)。
文摘Traditional Chinese medicine(TCM)has played a significant role in the prevention and treatment of chronic heart failure(CHF).To study TCM diagnosis of CHF,a total of 278 Chinese clinical research articles on the study of CHF syndromes in recent 40 years retrieved from Web of Science,Scopus,Pub Med,Embase,CNKI,Wanfang Data,Cq VIP,and Sino Med.According to cumulative frequency analysis,network analysis,and hierarchical cluster analysis,the study found the distribution of CHF syndromes was syndrome of qi deficiency with blood stasis,syndrome of qi and yin deficiency,syndrome of yang deficiency with water flooding,syndrome of heart blood stasis obstruction,syndrome of turbid phlegm,and syndrome of collapse due to primordial yang deficiency.The syndrome elements on location of illness were heart,kidney,lung,and spleen.The syndrome elements on nature of illness were qi deficiency,blood stasis,yang deficiency,yin deficiency,water retention,and turbid phlegm.These findings can provide reference to the research on diagnosis and treatment of CHF,and contribute to the study on syndrome standardization and objective research of TCM diagnosis.
基金supported by the National Natural Science Foundation of China(Grant Nos.12372201 and 12072302).
文摘The 13-node quadrilateral and 39-node hexahedral cubic serendipity elements produce nodally integrated positive-definite lumped heat capacity matrices in higher-order finite element analysis.However,these elements display severe convergence deterioration in explicit transient heat conduction analysis with lumped heat ca-pacity matrices.This convergence decay is due to the violation of variational integration consistency by the standard Galerkin formulation with lumped heat capacity matrices.This issue is resolved by introducing the boundary-enhanced Galerkin weak form that incorporates the elemental boundary contribution in the discrete finite element formulation.Subsequently,it is theoretically proven that a direct nodal integration identically fulfills the variational integration consistency in the context of the boundary-enhanced Galerkin weak form.The proposed variationally consistent nodal integration therefore enables optimal convergence for explicit transient heat conduction analysis with lumped heat capacity matrices.The efficacy of the proposed variationally con-sistent nodal integration formulation for the 13-node quadrilateral and 39-node hexahedral cubic elements is thoroughly demonstrated via numerical examples.
基金Supported by Fund of Sichuan Provincial Administration of traditional Chinese Medicine(2008-12)~~
文摘[Objective] This study aimed to investigate the trace elements in Rehman- nia glutinosa Libosch. by using principal component analysis and clustering analysis. [Method] Principal component analysis and clustering analysis of R. glutinosa medicinal materials from different sources were conducted with contents of six trace elements as indices. [Result] The principal component analysis could comprehen- sively evaluate the quality of R. glutinosa samples with objective results which was consistent with the results of clustering analysis. [Conclusion] Principal component analysis and clustering analysis methods can be used for the quality evaluation of Chinese medicinal materials with multiple indices.
基金supported by Independent Research Project of State Key Laboratory of Advanced Special Steel,Shanghai Key Laboratory of Advanced Ferrometallurgy,Shanghai University(SKLASS-2023-Z13)the Science and Technology Commission of Shanghai Municipality(No.19DZ2270200)+1 种基金A portion of the work was performed at US National High Magnetic Field Laboratory,which is supported by the National Science Foundation(Cooperative Agreement No.DMR-1157490 and DMR-1644779)the State of Florida.Thanks also to Mary Tyler for editing.
文摘The high-temperature dissolution behavior of primary carbides in samples taken from GCr15 continuous-casting bloom was observed in-situ by confocal laser scanning microscopy.Equations were fitted to the dissolution kinetics of primary carbides during either heating or soaking.Dissolution of carbides proceeded in three stages(fast→slow→faster)as either temperature or holding time was increased.During the heating process and during the first and third stages of the soaking process,the original size of the carbides determined the steepness of the slope,but during the middle(“slow”)stage of the soaking process,the slope remained zero.The initial size of the carbides varied greatly,but their final dissolution temperature fell within the narrow range of 1210-1235℃,and the holding time remained within 50 min.Fractal analysis was used to study the morphological characteristics of small and medium-sized carbides during the dissolution process.According to changes in the fractal dimension before and after soaking,the carbides tended to evolve towards a more regular morphology.
基金supported by the Science and Technology Research and Development Plan of the China State Railway Group Company Limited(No.Q2023J012).
文摘Purpose–The brake pipe system was an essential braking component of the railway freight trains,but the existing E-type sealing rings had problems such as insufficient low-temperature resistance,poor heat stability and short service life.To address these issues,low-phenyl silicone rubber was prepared and tested,and the finite element analysis and experimental studies on the sealing performance of its sealing rings were carried out.Design/methodology/approach–The low-temperature resistance and thermal stability of the prepared lowphenyl silicone rubber were studied using low-temperature tensile testing,differential scanning calorimetry,dynamic thermomechanical analysis and thermogravimetric analysis.The sealing performance of the lowphenyl silicone rubber sealing ring was studied by using finite element analysis software abaqus and experiments.Findings–The prepared low-phenyl silicone rubber sealing ring possessed excellent low-temperature resistance and thermal stability.According to the finite element analysis results,the finish of the flange sealing surface and groove outer edge should be ensured,and extrusion damage should be avoided.The sealing rings were more susceptible to damage in high compression ratio and/or low-temperature environments.When the sealing effect was ensured,a small compression ratio should be selected,and rubbers with hardness and elasticity less affected by temperature should be selected.The prepared low-phenyl silicone rubber sealing ring had zero leakage at both room temperature(RT)and�508C.Originality/value–The innovation of this study is that it provides valuable data and experience for the future development of the sealing rings used in the brake pipe flange joints of the railway freight cars in China.
文摘Total hip arthroplasty for adults with sequelae from childhood hip disorders poses significant challenges due to altered anatomy.The paper published by Oommen et al reviews the essential management strategies for these complex cases.This article explores the integration of finite element analysis(FEA)to enhance surgical precision and outcomes.FEA provides detailed biomechanical insights,aiding in preoperative planning,implant design,and surgical technique optimization.By simulating implant configurations and assessing bone quality,FEA helps in customizing implants and evaluating surgical techniques like subtrochanteric shortening osteotomy.Advanced imaging techniques,such as 3D printing,virtual reality,and augmented reality,further enhance total hip arthroplasty precision.Future research should focus on validating FEA models,developing patient-specific simulations,and promoting multidisciplinary collaboration.Integrating FEA and advanced technologies in total hip arthroplasty can improve functional outcomes,reduce complications,and enhance quality of life for patients with childhood hip disorder sequelae.
基金supported by the National Natural Science Foundation of China(Grant Nos.51890912,51979025 and 52011530189).
文摘This article presents a micro-structure tensor enhanced elasto-plastic finite element(FE)method to address strength anisotropy in three-dimensional(3D)soil slope stability analysis.The gravity increase method(GIM)is employed to analyze the stability of 3D anisotropic soil slopes.The accuracy of the proposed method is first verified against the data in the literature.We then simulate the 3D soil slope with a straight slope surface and the convex and concave slope surfaces with a 90turning corner to study the 3D effect on slope stability and the failure mechanism under anisotropy conditions.Based on our numerical results,the end effect significantly impacts the failure mechanism and safety factor.Anisotropy degree notably affects the safety factor,with higher degrees leading to deeper landslides.For concave slopes,they can be approximated by straight slopes with suitable boundary conditions to assess their stability.Furthermore,a case study of the Saint-Alban test embankment A in Quebec,Canada,is provided to demonstrate the applicability of the proposed FE model.
文摘Design a precision electroplating mechanical structure for automobiles based on finite element analysis method and analyze its mechanical properties.Taking the automobile steering knuckle as the research object,ABAQUS parametric modeling technology is used to construct its three-dimensional geometric model,and geometric simplification is carried out.Two surface treatment processes,HK-35 zinc nickel alloy electroplating and pure zinc electroplating,were designed,and the influence of different coatings on the mechanical properties of steering knuckles was compared and analyzed through numerical simulation.At the same time,standard specimens were prepared for salt spray corrosion testing and scratch method combined strength testing to verify the numerical simulation results.The results showed that under emergency braking and composite working conditions,the peak Von Mises stress of the zinc nickel alloy coating was 119.85 MPa,which was lower than that of the pure zinc coating and the alkaline electroplated zinc layer.Its equivalent strain value was 652×10^(-6),which was lower than that of the pure zinc coating and the alkaline electroplated zinc layer.Experimental data confirms that zinc nickel alloy coatings exhibit significant advantages in stress distribution uniformity,strain performance,and load-bearing capacity in high stress zones.The salt spray corrosion test further indicates that the coating has superior corrosion resistance and coating substrate interface bonding strength,which can significantly improve the mechanical stability and long-term reliability of automotive precision electroplating mechanical structures.
文摘Objective: To compare the stress distribution in the periodontal ligament under different orthodontic forces during canine distalization using long-arm brackets, and to determine the optimal force value for this device in orthodontic treatment. Methods: A finite element model was constructed after extracting the mandibular first premolar, and a long-arm bracket with a traction height of 6 mm was placed on the labial side of the mandibular canine. Three working conditions of 50 g, 100 g, and 150 g were simulated, and the magnitude and distribution of von Mises stress in the periodontal ligament were compared for each condition. Results: The maximum von Mises stress in the periodontal ligament was 0.013281 MPa in the 50 g condition, 0.02536 MPa in the 100 g condition, and 0.035549 MPa in the 150 g condition. As the orthodontic force increased, the stress distribution area in the periodontal ligament also expanded. Conclusion: A 100 g orthodontic force is the most suitable when using long-arm brackets, providing a relatively uniform stress distribution in the periodontal ligament and keeping the stress within a reasonable range.
文摘To effectively address the challenge where the speed of tunnel lining construction struggles to match that of tunnel face and inverted arch construction,and to enhance the quality of secondary lining,a new type of skeleton-free,traversing secondary lining trolley has been developed.This trolley features a set of gantries paired with two sets of formwork.The formwork adopts a multi-segment hinged and strengthened design,ensuring its own strength can meet the requirements of secondary lining concrete pouring without relying on the support of the gantries.When retracted,the formwork can be transported by the gantries through another set of formwork in the supporting state,enabling early formwork support,effectively accelerating the construction progress of the tunnel’s secondary lining,and extending the maintenance time of the secondary lining with the formwork.Finite element software modeling was used for simulation calculations,and the results indicate that the structural strength,stiffness,and other performance parameters of the new secondary lining trolley meet the design requirements,verifying the rationality of the design.
基金supported by Scientific Research Projects Department of Istanbul Technical University.Project Number:MGA-2018-41546.Grant receiver:E.T.
文摘Due to their superior properties, the interest in nanostructures is increasing today in engineering. This study presents a new two-noded curved finite element for analyzing the in-plane static behaviors of curved nanobeams. Opposite to traditional curved finite elements developed by using approximate interpolation functions, the proposed curved finite element is developed by using exact analytical solutions. Although this approach was first introduced for analyzing the mechanical behaviors of macro-scale curved beams by adopting the local theory of elasticity, the exact analytical expressions used in this study were obtained from the solutions of governing equations that were expressed via the differential form of the nonlocal theory of elasticity. Therefore, the effects of shear strain and axial extension included in the analytical formulation are also inherited by the curved finite element developed here. The rigidity matrix and the consistent force vector are developed for a circular finite element. To demonstrate the applicability of the method, static analyses of various curved nanobeams subjected to different boundary conditions and loading scenarios are performed, and the obtained results are compared with the exact analytical ones. The presented study provides an accurate and low computational cost method for researchers to investigate the in-plane static behavior of curved nanobeams.
基金supported by the National Natural Science Foundation of China(No.52278251)Guizhou Provincial Sciences and Technology Projects(ZK[2022]Key 007).
文摘Identifying the damage and fracture properties of nuclear graphite materials and accurately simulating them are crucial when designing graphite core structures.To simulate the damage evolution and crack propagation of graphite under stress in a finite element model,compression tests on disks and three-point bending tests on center-notched beams for fine-grained graphite(CDI-1D and IG11 graphite)were conducted.During these tests,digital image correlation and electronic speckle pattern interferometry techniques were utilized to observe the surface full-field displacements of the specimens.A segmented finite element inverse analysis method was developed to characterize the graphite’s damage evolution by quantifying the reduction in Young’s modulus with tensile and compressive strains in disk specimens.The fracture energy and bilinear tensile softening curve of the graphite were determined by comparing the load–displacement responses of the three-point bending tests and the finite element simulation.Finally,by combining the identified damage laws with a fracture criterion based on fracture energy,a damage–fracture model was established and used to simulate tensile tests on L-shaped specimens with different fillet radii.Simulations indicate that the damage area at the fillet expands with increasing radius,creating a blunting effect that enhances the load-bearing capacity of the specimens.This damage–fracture model can be applied to simulate graphite components in core structures.
文摘The increasing occurrence of sinkholes caused by water main bursts has attracted significant research attention in recent years.This study addresses the gap in evaluating soil blowout stability resulting from water main failures by investigating the three-dimensional stability of blowouts with circular,hemispherical,and spherical openings.Advanced finite element limit analysis(FELA)combined with adaptive meshing is employed to analyze critical factors,including soil cover depth,surcharge pressure,and internal water pressure,that contribute to blowout failure.In addition,dimensionless ratios are used throughout the paper to assess the influence of these factors.Numerical findings are rigorously validated,ensuring reliability and accuracy.Practical design charts are provided to accommodate a wide range of design scenarios,offering valuable guidance for engineers.This study introduces a pioneering sinkhole simulation methodology,leading to the understanding of three-dimensional blowout stability mechanisms.
基金supported by the National Natural Science Foundation of China(Grant No.U2330208).
文摘The incorporation of graphene fillers into polymer matrices has been recognized for its potential to enhance thermal conductivity,which is particularly beneficial for applications in thermal management.The uniformity of graphene dispersion is pivotal to achieving optimal thermal conductivity,thereby directly influencing the effectiveness of thermal management,including the mitigation of local hot-spot temperatures.This research employs a quantitative approach to assess the distribution of graphene fillers within a PBX(plastic-bonded explosive)matrix,focusing specifically on the thermal management of hot spots.Through finite element method(FEM)simulations,we have explored the impact of graphene filler orientation,proximity to the central heat source,and spatial clustering on heat transfer.Our findings indicate that the strategic distribution of graphene fillers can create efficient thermal conduction channels,which significantly reduce the temperatures at local hot spots.In a model containing 0.336%graphene by volume,the central hot-spot temperature was reduced by approximately 60 K compared to a pure PBX material,under a heat flux of 600 W/m^(2).This study offers valuable insights into the optimization of the spatial arrangement of low-concentration graphene fillers,aiming to improve the thermal management capabilities of HMX-based PBX explosives.
基金supported by the Science and Technology Research and Development Plan of the China State Railway Group Company Limited(Grant No.N2023J053).
文摘Purpose–Type-120 relief valves are critical components of locomotive braking systems,and they rapidly discharge the air pressure during brake release to enable swift pressure relief.In order to develop type-120 relief valve rubber diaphragms with long life and high performance,the damaged faulty samples were analyzed and studied.Design/methodology/approach–Finite element analysis(FEA)was used to investigate the stress distribution and failure mechanism of the rubber diaphragms within the type-120 relief valves under dynamic loading conditions.The Ogden hyperelastic constitutive model was used to fit the diaphragm data obtained from the uniaxial tensile tests,and its suitability for the modeling of large deformations was confirmed.Findings–The FEA results indicated that,when the rubber diaphragms reached their maximum deformation,the peak stress on their upper surfaces was 5.44 MPa.Thus,this region is highly susceptible to fatigue damage.The service life of the rubber diaphragms could be extended by using rubber compounds with high tensile moduli or a fabric-reinforced rubber diaphragm.Originality/value–This study provides valuable data and experience for the development of the rubber diaphragms in the type-120 valves and other long-life rubber products in the railway field.
文摘Purpose–This paper aims to offer a novel viewpoint for improving performance and reliability by developing and optimizing suspension components in a Y25 bogie through material optimization based on wheel–rail interactions under variable load and track conditions.Design/methodology/approach–The suspension system,a critical component ensuring adaptation to road and load conditions in all vehicle types,is especially vital in heavy freight and passenger trains.In this context,the suspension set of the Y25 bogie–commonly used in T€urkiye and Europe–was modelled using CATIAV5,and stress analyses have been performed by way of ANSYS using the finite element analysis(FEA)method.E300-520-M cast steel was selected for the bogie frame,while two different spring steels,61SiCr7 and 51CrV4,were considered for the suspension springs.The modeled system was subjected to numerical analysis under loading conditions.The resulting stresses and displacements were compared with the mechanical properties of the selected materials to validate the design.Findings–The results demonstrate that the mechanical strength and deformation characteristics of the suspension components vary according to the applied external loads.The stress and displacement responses of the system were found to be within the allowable limits of the selected materials,confirming the structural integrity and reliability of the design.The suspension set is deemed suitable for the prescribed material and environmental conditions,suggesting potential for practical application in real-world rail systems.Originality/value–This research contributes to the design and optimization of bogie suspension systems using advanced CAD/CAE tools.It thinks that the material selection and numerical validation approach presented here can guide future designs in heavy load rail applications and potentially improve both safety and performance.
基金support from Outstanding Youth Fund of Jiangsu Province(BK20240077)Key Project(Provincial-Municipal Joint)of Jiangsu Province(BK20243044)+2 种基金Fundamental Research Funds for the Central Universities(NE2024001)National Youth Talents Programof Chinaa project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions.
文摘Microstructure topology evolution during severe plastic deformation(SPD)is crucial for understanding and optimising the mechanical properties of metallic materials,though its prediction remains challenging.Herein,we combine discrete cell complexes(DCC),a fully discrete algebraic topology model-with finite element analysis(FEA)to simulate and analyse the microstructure topology of pure copper under SPD.Using DCC,we model the evolution of microstructure topology characterised by Betti numbers(β_(0),β_(1),β_(2))and Euler characteristic(χ).This captures key changes in GBNs and topological features within representative volume elements(RVEs)containing several hundred grains during SPD-induced recrystallisation.As SPD cycles increase,high-angle grain boundaries(HAGBs)progressively form.Topological analysis reveals an overall decrease in β_(0)values,indicating fewer isolated HAGB substructures,while β_(2) values show a steady upward trend,highlighting new grain formation.Leveraging DCC-derived RVE topology and FEA-generated plastic strain data,we directly simulate the evolution and spatial distribution of microstructure topology and HAGB fraction in a copper tube undergoing cyclic parallel tube channel angular pressing(PTCAP),a representative SPD technique.Within the tube,the HAGB fraction continuously increases with PTCAP cycles,reflecting the microstructure’s gradual transition from subgrains to fully-formed grains.Analysis of Betti number distribution and evolution reveals the microstructural reconstruction mechanism underpinning this subgrain to grain transition during PTCAP.We further demonstrate the significant influence of spatially non-uniform plastic strain distribution on microstructure reconstruction kinetics.This study demonstrates a feasible approach for simulating microstructure topology evolution of metals processed by cyclic SPD via the integration of DCC and FEA.
文摘In this work, the finite element analysis of the elasto-plastic plate bending problems is carried out using transition rectangular plate elements. The shape functions of the transition plate elements are derived based on a practical rule. The transition plate elements are all quadrilateral and can be used to obtain efficient finite element models using minimum number of elements. The mesh convergence rates of the models including the transition elements are compared with the regular element models. To verify the developed elements, simple tests are demonstrated and various elasto-plastic problems are solved. Their results are compared with ANSYS results.
基金Project(2007CB714202) supported by the National Key Basic Research Program of ChinaProject(SLDRCE10-B-07) supported by theMinistry of Science and Technology of China
文摘An element coupling model (ECM) method was proposed to simulate the global behavior and local damage of a structure.In order to reflect the local damage and improve the computational efficiency,three-dimensional (3D) solid elements and one-dimensional (1D) beam element were coupled by the multi-point constraint equations.A reduced scale 1?8 model test was simulated by the ECM and a full three dimensional model (3DM) contrastively.The results show that the global behavior and local damages of ECM agree well with the test and 3DM.It is indicated that the proposed method can be used in the structural nonlinear analysis accurately and efficiently.