BACKGROUND Pedicle screw fixation is frequently used to treat unstable thoracolumbar injuries;however,the rate of instrumentation failure remains considerable.The primary contributing factor leading to instrumentation...BACKGROUND Pedicle screw fixation is frequently used to treat unstable thoracolumbar injuries;however,the rate of instrumentation failure remains considerable.The primary contributing factor leading to instrumentation failure is poor bone quality.On the other hand,some evidence suggests that surgical tactics can influence long-term instrumentation stability.AIM To assess factors that influence the stability of spinal instrumentation in patients with thoracolumbar injuries.METHODS This study is a non-randomized single center ambispective evaluation of 204 consecutive patients(117 men;87 women)with unstable thoracolumbar injuries.All patients underwent either stand-alone or combined with anterior column reconstruction instrumentation.In cases with spinal cord and nerve root injuries,either posterior or anterior decompression were performed.Patients with pedicle screw loosening were identified via computed tomography imaging.Out of those,cases with clinically significant instrumentation failure were registered.RESULTS The rate of pedicle screw loosening detected by computed tomography was inversely correlated with bone radiodensity figures and an increased association with the number of instrumented levels,residual kyphotic deformity,laminectomy,and lumbosacral fixation.Intermediate screws and anterior reconstruction were associated with a clinically relevant decreased risk of pedicle screw loosening development.Either complete or partial posterior fusion within instrumented levels was capable of decreasing instrumentation failure risk,while extensive decompression with laminectomy and at least one-level total facetectomy were associated with an increased risk of instrumentation failure.Anterior decompression does not have a negative impact on instrumentation stability.CONCLUSION Intermediate screws,anterior reconstruction and posterior tension band preservation are associated with decreased rates of instrumentation instability development.Posterior fusion is beneficial in terms of instrumentation failure prevention.展开更多
Low-visibility phenomena strongly impact the environment,as well as transportation,aviation and other fields that are closely related to people's livelihoods;thus,they represent important ecological issues of soci...Low-visibility phenomena strongly impact the environment,as well as transportation,aviation and other fields that are closely related to people's livelihoods;thus,they represent important ecological issues of social concern.Based on observation data concerning low-visibility phenomena derived from 105 national meteorological stations in Xinjiang,China over the past 20 years,we systematically analyzed the differences between manual and instrument observations for six types of low-visibility phenomena,with a focus on exploring their spatiotemporal distribution characteristics using instrument data.The results revealed that low-visibility phenomena were dominated by fog-and haze-related events(mist,fog,and haze)in northern Xinjiang and dust-related events(dust storms,blowing sand,and floating dust)in southern Xinjiang,with transitional characteristics observed in eastern Xinjiang.Compared with manual observations,the instrument measurements significantly improved the fine-scale low-visibility phenomenon identification process.On the basis of the instrument observation data,spatial-dimension analysis results indicated that low-visibility phenomena in Xinjiang were significantly influenced by terrain factors.Constrained by the Tianshan Mountains,haze-like phenomena formed a core agglomeration area in northern Xinjiang,whereas dust-and sand-related phenomena radiated outward,with the Taklimakan Desert at the center.Moreover,the gripping effect of the terrain promoted dust transmission along low-altitude channels.Temporally,fog-and haze-related phenomena occurred mainly during autumn and winter,and the proportion of these events decreased from 76.7%to 55.1%.The fog-and haze-related phenomena demonstrated a U-shaped rebound trend,while the proportion of mist phenomena decreased by 34.2%.Dust storms occurred during spring,accounting for 23.3%to 44.9%of all storms.Instrument measurement technology has the advantages of high spatial and temporal resolutions and multiparameter coordination but provides a limited dust-haze mixed-pollution identification capacity.This study provides crucial reference data for enhancing the understanding of low-visibility events in Xinjiang and the potential responses while improving the accuracy of pollution source tracking and meteorological process diagnosis tasks.展开更多
Scientific instruments serve as foundational pillars for both scientific progress and industrial innovation,enabling deep exploration and driving technological breakthroughs.Their independent controllability and conti...Scientific instruments serve as foundational pillars for both scientific progress and industrial innovation,enabling deep exploration and driving technological breakthroughs.Their independent controllability and continuous innovation are indispensable for sustaining a competitive advantage in technological development,thereby securing national scientific capacity and long-term strategic growth.At present,however,China faces substantial risks of technological"stranglehold"in the high-end scientific instrument domain.The underlying causes are multifaceted,arising not only from insufficient accumulation of core technologies but also from entrenched systemic and ecosystem-level barriers that impede the application,scaling,and promotion of domestic instruments.This paper provides a systematic analysis of the challenges hindering the widespread adoption of domestically developed scientific instruments and proposes practical pathways to build a new,integrated"R&D-application-promotion"ecosystem.This ecosystem is anchored in trust,driven by user demand,and shaped through collaborative innovation.Key initiatives include organizing user visits to instrument manufacturers,convening seminars on domestic alternatives to imported equipment,establishing demonstration centers for application and promotion,and involving end-users directly in the R&D and iterative upgrading of domestic instruments.Together,these efforts aim to close the final critical gap,advancing domestic instruments from merely"functional"to genuinely"user-friendly",and ultimately to"widely implemented".By doing so,this framework offers both theoretical grounding and practical guidance for achieving high-level scientific and technological self-reliance and sustained innovation capacity.展开更多
Chinese video game Black Myth:Wukong has been a h it among gaming enthusiasts worldwide since its release in 2024, its breakout success demonstrating the potential global appeal of traditional Chinese culture. Based o...Chinese video game Black Myth:Wukong has been a h it among gaming enthusiasts worldwide since its release in 2024, its breakout success demonstrating the potential global appeal of traditional Chinese culture. Based on the 16th-century classic novel Journey to the West, the game not only introduces international audiences to Chinese literature but has also become a far-reaching platform for traditional Chinese music.展开更多
AIM: To summarise and compare currently available evidence regarding accuracy of pre-operative imaging, which is one of the key choices for surgeons contemplating patient-specific instrumentation(PSI) surgery.METHODS:...AIM: To summarise and compare currently available evidence regarding accuracy of pre-operative imaging, which is one of the key choices for surgeons contemplating patient-specific instrumentation(PSI) surgery.METHODS: The MEDLINE and EMBASE medical literature databases were searched, from January 1990 to December 2013, to identify relevant studies. The data from several clinical studies was assimilated to allow appreciation and comparison of the accuracy of each modality. The overall accuracy of each modality was calculated as proportion of outliers > 3% in the coronal plane of both computerised tomography(CT) or magnetic resonance imaging(MRI). RESULTS: Seven clinical studies matched our inclusion criteria for comparison and were included in our study for statistical analysis. Three of these reported series using MRI and four with CT. Overall percentage of outliers > 3% in patients with CT-based PSI systems was 12.5% vs 16.9% for MRI-based systems. These results were not statistically significant. CONCLUSION: Although many studies have been undertaken to determine the ideal pre-operative imaging modality, conclusions remain speculative in the absence of long term data. Ultimately, information regarding accuracy of CT and MRI will be the main determining factor. Increased accuracy of pre-operative imaging could result in longer-term savings, and reduced accumulated dose of radiation by eliminating the need for post-operative imaging and revision surgery.展开更多
Patient specific instrumentation(PSI) in total knee arthroplasty(TKA) promises faster operation time(by using less instruments and individual cutting jigs), less blood loss, faster rehabilitation, better implant sizin...Patient specific instrumentation(PSI) in total knee arthroplasty(TKA) promises faster operation time(by using less instruments and individual cutting jigs), less blood loss, faster rehabilitation, better implant sizing and accuracy, superior overall outcome, and at the end- less costs. However, as evident for every new development, its superiority remains to be provenover the conventional systems. Whilst dissatisfaction is reported to be eminent in up to 30% of patients having undergone conventional TKA, it is unclear, whether PSI can address to these patients as a suitable option in the future. The author believes that the current evidence does not support superiority of PSI in TKA over conventional systems. However, future long-term level I and II studies might aid to show its cost-effectiveness stating same results, accuracy, and overall outcome with less operation time.展开更多
In this study,the behavior of Gavoshan dam was evaluated during construction and the first impounding.A two-dimensional（2D） numerical analysis was conducted based on a finite difference method on the largest cross-s...In this study,the behavior of Gavoshan dam was evaluated during construction and the first impounding.A two-dimensional（2D） numerical analysis was conducted based on a finite difference method on the largest cross-section of the dam using the results of instrument measurements and back analysis.These evaluations will be completed in the case that back analysis is carried out in order to control the degree of the accuracy and the level of confidence of the measured behavior since each of the measurements could be controlled by comparing it to the result obtained from the numerical model.Following that,by comparing the results of the numerical analysis with the measured values,it is indicated that there is a proper consistency between these two values.Moreover,it was observed that the dam performance was suitable regarding the induced pore water pressure,the pore water pressure ratio r;,settlement,induced stresses,arching degree,and hydraulic fracturing probability during the construction and initial impounding periods.The results demonstrated that the maximum settlement of the core was 238 cm at the end of construction.In the following 6 years after construction（initial impounding and exploitation period）,the accumulative settlement of the dam was 270 cm.It is clear that 88% of the total settlement of the dam took place during dam construction.The reason is that the clay core was smashed in the wet side,i.e.the optimum moisture content.Whereas the average curving ratio was 0.64 during dam construction; at the end of the initial impounding,the maximum amount of curving ratio in the upstream was 0.81,and the minimum（critical） amount in the downstream was 0.52.It was also concluded that this dam is safe in comparison with the behaviors of other similar dams in the world.展开更多
Ventilation fans are one of the most important pieces of equipment in coal mines. Their performance plays an important role in the safety of staff and production. Given the actual requirements of coal mine production,...Ventilation fans are one of the most important pieces of equipment in coal mines. Their performance plays an important role in the safety of staff and production. Given the actual requirements of coal mine production,we instituted a research project on the measurement methods of key performance parameters such as wind pressure,amount of ventilation and power. At the end a virtual instrument for mine ventilation fans performance evaluation was developed using a USB interface. The practical performance and analytical results of our experiments show that it is feasible,reliable and effective to use the proposed instrumentation for mine ventilation performance evaluation.展开更多
Capillary electrophoresis-mass spectrometry（CE-MS） is a powerful separation and analytical technique in the field of analytical chemistry. This review provides an update of instrumentation developments in the method...Capillary electrophoresis-mass spectrometry（CE-MS） is a powerful separation and analytical technique in the field of analytical chemistry. This review provides an update of instrumentation developments in the methodology of CE-MS systems. A selection of relevant articles covers the literatures published from Jan. 2013 to Feb. 2017. Special attentions were paid to the sample injection and ionization processes.Applications of these CE-MS systems were also introduced through representative examples. General conclusions and perspectives were given at the last.展开更多
Pelvic instrumentation for neuromuscular scoliosis has been part of neuromuscular scoliosis surgery since the era of the Luque Galveston construct. Unit Rod(Medtronic Sofamor-Danek, Nashville, TN) instrumentation brou...Pelvic instrumentation for neuromuscular scoliosis has been part of neuromuscular scoliosis surgery since the era of the Luque Galveston construct. Unit Rod(Medtronic Sofamor-Danek, Nashville, TN) instrumentation brought with it the concept of cantilever correction by placing the implants in the pelvis and then gradually bringing the rod to the spine by sequentially tightening the sublaminar wires, with the goal of creating a level pelvis over a straight spine. More recently surgeons have utilized pedicle screw constructs in which the corrective strategies have varied. Challenges with pelvic fixation using iliac screws linked to the spinal rod have led to the development of the S2-alariliac technique(S2 AI) in which the spinal rod connects to the pelvic screw. The screw is placed in the S2 ala, crosses the sacro-iliac joint and into the ilium through a large column of supra-acetabular bone. This column is the same area used for anterior inferior iliac spine external fixation frames used in trauma surgery. S2 AI screw placement can be technically difficult and can require experienced radiology technologists to provide the appropriate views. Additionally, although the technique was originally described being placed via freehand technique with intra-operative flouroscopy, the freehand technique suffers from the anatomic anomalies present in the pelvis in neuromuscular scoliosis. As such, we prefer to place them using intra-operative navigation for all pediatric spinal deformity cases. Below in detail we report our intra-operative technique and an illustrative case example.展开更多
Seismic networks have significantly improved in the last decade in terms of coverage density,data quality,and instrumental diversity.Moreover,revolutionary advances in ultra-dense seismic instruments,such as nodes and...Seismic networks have significantly improved in the last decade in terms of coverage density,data quality,and instrumental diversity.Moreover,revolutionary advances in ultra-dense seismic instruments,such as nodes and fiber-optic sensing technologies,have recently provided unprecedented high-resolution data for regional and local earthquake monitoring.Nodal arrays have characteristics such as easy installation and flexible apertures,but are limited in power efficiency and data storage and thus most suitable as temporary networks.Fiber-optic sensing techniques,including distributed acoustic sensing,can be operated in real time with an in-house power supply and connected data storage,thereby exhibiting the potential of becoming next-generation permanent networks.Fiber-optic sensing techniques offer a powerful way of filling the observation gap particularly in submarine environments.Despite these technological advancements,various challenges remain.First,the data characteristics of fiber-optic sensing are still unclear.Second,it is challenging to construct software infrastructures to store,transfer,visualize,and process large amount of seismic data.Finally,innovative detection methods are required to exploit the potential of numerous channels.With improved knowledge about data characteristics,enhanced software infrastructures,and suitable data processing techniques,these innovations in seismic instrumentation could profoundly impact observational seismology.展开更多
BACKGROUND Over the past years,patient specific instrumentation(PSI)for total knee arthroplasty(TKA)has been implemented and routinely used.No clear answer has been given on its associated cost and cost-effectiveness ...BACKGROUND Over the past years,patient specific instrumentation(PSI)for total knee arthroplasty(TKA)has been implemented and routinely used.No clear answer has been given on its associated cost and cost-effectiveness when compared to conventional instrumentation(CI)for TKA.AIM To compare the cost and cost-effectiveness of PSI TKA compared to CI TKA.METHODS A literature search was performed in healthcare,economical healthcare,and medical databases(MEDLINE,EMBASE,CINAHL,Web of Science,Cochrane Library,EconLit).It was conducted in April 2021 and again in January 2022.Relevant literature included randomised controlled trials,retrospective studies,prospective studies,observational studies,and case control studies.All studies were assessed on methodological quality.Relevant outcomes included incremental cost-effectiveness ratio,quality-adjusted life years,total costs,imaging costs,production costs,sterilization associated costs,surgery duration costs and readmission rate costs.All eligible studies were assessed for risk of bias.Meta-analysis was performed for outcomes with sufficient data.RESULTS Thirty-two studies were included into the systematic review.Two were included in the metaanalysis.3994 PSI TKAs and 13267 CI TKAs were included in the sample size.The methodological quality of the included studies,based on Consensus on Health Economic Criteria-scores and risk of bias,ranged from average to good.PSI TKA costs less than CI TKA when considering mean operating room time and its associated costs and tray sterilization per patient case.PSI TKA costs more compared to CI TKA when considering imaging and production costs.Considering total costs per patient case,PSI TKA is more expensive in comparison to CI TKA.Meta-analysis comparing total costs for PSI TKA,and CI TKA showed a significant higher cost for PSI TKA.CONCLUSION Cost for PSI and CI TKA can differ when considering distinct aspects of their implementation.Total costs per patient case are increased for PSI TKA when compared to CI TKA.展开更多
Objective. To introduce a new spinal internal fixation system, Texas Scottish Rite Hospital (TSRH), and to investigate its early clinical outcomes.Methods. The preliminary clinical outcomes of 15 patients with thoraco...Objective. To introduce a new spinal internal fixation system, Texas Scottish Rite Hospital (TSRH), and to investigate its early clinical outcomes.Methods. The preliminary clinical outcomes of 15 patients with thoracolumbar or lumbar scoliosis treated by anterior spinal fusion with TSRH instrumentation were studied retrospectively. Fourteen patients were diagnosed as idiopathic scoliosis and 1 as neuromuscular scoliosis.Results. Preoperatively, the Cobb's angle on the coronal plane was 55. 8° (range 35° - 78°), and 14° postoperatively, with an average correction of 74. 8 %. The average unfused thoracical curve was 35. 9 ° preoperatively (range 26° - 51°) and 21. 8° (10°-42° ) postoperatively, with 40% correction. The sagittal curve of lumbar was kept physiologically, preoperative 27. 9° and postoperative 25. 7° respectively. The trunk shift was 13.4 mm (5 - 28mm) preoperatively and 3. 5 mm (0-7 mm) postoperatively. The averaged apic vertebra derivation was 47. 8 mm (21 - 69 mm) before operation and 10. 8 mm (3-20 mm) after operation. The distance of C7 to center sacrum vertical line (CSVL) was 19. 5 mm(16 - 42)preoperatively and 11. 3 mm (0-32 mm) postoperatively. The apical vertebra rotation was 3 degree in 15 patients preoperatively, and were improved to normal in 10 patients, 1 degree in 4 patients, and 2 degree in 1 patients postoperatively. None had neurological injury and infection. Only 1 patient complained a cool feeling in the low extremity of concave side, and the symptom vanished at 3-month followed up.Conclusion. If used appropriately, TSRH anterior spinal system is a good treatment for low thoracic or thoracic lumbar scoliosis.展开更多
Objective. To evaluate the results of TSRH instrumentation in the correction of coronal, sagittal and rotational deformity of scoliosis. Methods. From January 1998 to December 1999, thirty- two consecutive patients (6...Objective. To evaluate the results of TSRH instrumentation in the correction of coronal, sagittal and rotational deformity of scoliosis. Methods. From January 1998 to December 1999, thirty- two consecutive patients (6 males, 26 females) with scoliosis underwent anterior or posterior spinal instrumentation and fusion using TSRH instrumentation. Of these cases, 21 were idiopathic scoliosis and 11 were congenital scoliosis. The average age at surgery was 16.4 years (range, 11～ 45 years). The mean Cobb angle at surgery was 71 .2 (range, 44～ 125 ) in the coronal plane, and 49.2 ( range, 16～ 67 ) in the sagittal plane. Rotational deformity (Nash- Moe) ranged from I to III degree. Preoperative apical translation averaged 4.8 cm (range, 3～ 9 cm). Results. The average follow- up duration was 13.3 months (range, 10～ 24 months).At the final follow- up, the mean Cobb angle in the coronal plane was 26. 6 (range, 10～ 73 ),with a 63.8％ of improvement. Sagittal alignment was well maintained with a mean Cobb angle of 28 ( range, 10～ 45 ). The average correction of rotation of the apical vertebra was I degree. The average apical translation was 1.6 cm (range, 0.5～ 5.0 cm) representing a correction rate of 66,7％ . Complication was noted in two cases with an incidence of 3.1％ , one case had superficial infection and the other one had lower hook dislocation.There was no neurologic deficit and pseudoarthrodesis in this series. Conclusion. TSRH instrumentation is an effective and convenient three- dimensional correction system with a lower rate of complication, which can not only correct the coronal and rotational deformity, but maintain the sagittal alignment as well.展开更多
The recent increase in the adoption of total ankle arthroplasty(TAA)reflects the improvements in implant designs and surgical techniques,including the use of preoperative navigation system and patient-specific instrum...The recent increase in the adoption of total ankle arthroplasty(TAA)reflects the improvements in implant designs and surgical techniques,including the use of preoperative navigation system and patient-specific instrumentation(PSI),such as custom-made cutting guides.Cutting guides are customized with respect to each patient's anatomy based on preoperative ankle computed tomography scans,and they drive the saw intra-operatively to improve the accuracy of bone resection and implant positioning.Despite some promising results,the main queries in the literature are whether PSI improves the reliability of achieving neutral ankle alignment and more accurate implant sizing,whether it is actually superior over standard techniques,and whether it is cost effective.Moreover,the advantages of PSI in clinical outcomes are still theoretical because the current literature does not allow to confirm its superiority.The purpose of this review article is therefore to assess the current literature on PSI in TAA with regard to current implants with PSI,templating and preoperative planning strategies,alignment and sizing,clinical outcomes,cost analysis,and comparison with standard techniques.展开更多
-A Portable gas chromatograPhy (GC) instrument is presented in this paper. In this GC instrument a new gaseous sampling device was used in place of conventional sampling valves.It has no quantitative tube or movable c...-A Portable gas chromatograPhy (GC) instrument is presented in this paper. In this GC instrument a new gaseous sampling device was used in place of conventional sampling valves.It has no quantitative tube or movable components in the sample Path. The sampling size si determined by time with a high precision,which is not sensitive to the sample temperature and pressure.Especially,the sample can not only inject into the column head,but also the carrier gas blow the column reversely and clean it.The portable GC instrument based on the sampling device can be used in enviromental and biomedical monitoring.展开更多
This paper deals with instrumenting a mechatronic system,through the incorporation of suitable sensors,actuators,and other required hardware.Sensors(e.g.,semiconductor strain gauges,tachometers,RTD temperature sensors...This paper deals with instrumenting a mechatronic system,through the incorporation of suitable sensors,actuators,and other required hardware.Sensors(e.g.,semiconductor strain gauges,tachometers,RTD temperature sensors,cameras,piezoelectric accelerometers)are needed to measure(sense)unknown signals and parameters of a system and its environment.The information acquired in this manner is useful in operating or controlling the system,and also in process monitoring;experimental modeling(i.e.,model identification);product testing and qualification;product quality assessment;fault prediction,detection and diagnosis;warning generation;surveillance,and so on.Actuators(e.g.,stepper motors,solenoids,dc motors,hydraulic rams,pumps,heaters/coolers)are needed to"drive"a plant.Control actuators(e.g.,control valves)perform control actions,and in particular they drive control devices.Micro-electromechanical systems(MEMS)use microminiature sensors and actuators.MEMS sensors commonly use piezoelectric,capacitive,electromagnetic and piezoresistive principles.MEMS devices provide the benefits of small size and light weight(negligible loading errors),high speed(high bandwidth),and convenient mass-production(low cost).The process of instrumentation involves the identification of proper sensors,actuators,controllers,signal modification/interface hardware,and software with respect to their functions,operation,parameters,ratings,interaction with each other,so as to achieve the performance requirements of the overall system,and interfacing/integration/tuning of the selected devices into the system,for a given application.This paper presents the key steps of instrumenting a mechatronic system,in a somewhat general and systematic manner.Examples are described to illustrate several key procedures of instrumentation.展开更多
In 2015,the U.S National Institute of Standards and Technology(NIST)funded the Center of Excellence for Risk-Based Community Resilience Planning(CoE),a fourteen university-based consortium of almost 100 col-laborators...In 2015,the U.S National Institute of Standards and Technology(NIST)funded the Center of Excellence for Risk-Based Community Resilience Planning(CoE),a fourteen university-based consortium of almost 100 col-laborators,including faculty,students,post-doctoral scholars,and NIST researchers.This paper highlights the scientific theory behind the state-of-the-art cloud platform being developed by the CoE-the Interdisciplinary Networked Community Resilience Modeling Environment(IN-CORE).IN-CORE enables communities,consul-tants,and researchers to set up complex interdependent models of an entire community consisting of people,businesses,social institutions,buildings,transportation networks,water networks,and electric power networks and to predict their performance and recovery to hazard scenario events,including uncertainty propagation through the chained models.The modeling environment includes a detailed building inventory,hazard scenario models,building and infrastructure damage(fragility)and recovery functions,social science data-driven house-hold and business models,and computable general equilibrium(CGE)models of local economies.An important aspect of IN-CORE is the characterization of uncertainty and its propagation throughout the chained models of the platform.Three illustrative examples of community testbeds are presented that look at hazard impacts and recovery on population,economics,physical services,and social services.An overview of the IN-CORE technology and scientific implementation is described with a focus on four key community stability areas(CSA)that encompass an array of community resilience metrics(CRM)and support community resilience informed decision-making.Each testbed within IN-CORE has been developed by a team of engineers,social scientists,urban planners,and economists.Community models,begin with a community description,i.e.,people,businesses,buildings,infras-tructure,and progresses to the damage and loss of functions caused by a hazard scenario,i.e.,a flood,tornado,hurricane,or earthquake.This process is accomplished through chaining of modular algorithms,as described.The baseline community characteristics and the hazard-induced damage sets are the initial conditions for the recovery models,which have been the least studied area of community resilience but arguably one of the most important.Communities can then test the effect of mitigation and/or policies and compare the effects of“what if”scenarios on physical,social,and economic metrics with the only requirement being that the change much be able to be numerically modeled in IN-CORE.展开更多
BACKGROUND We report a case of Intracardiac,pulmonary,and intravenous cement embolism after cement-augmented pedicle screw instrumentation in treating spondylolisthesis underlying osteoporotic bone,which was successfu...BACKGROUND We report a case of Intracardiac,pulmonary,and intravenous cement embolism after cement-augmented pedicle screw instrumentation in treating spondylolisthesis underlying osteoporotic bone,which was successfully managed by conservative treatment.We describe the treatment and outcome of the patient,hoping to shed light on the management of bone cement embolism.CASE SUMMARY A 67-year-old female suffered from progressive low back pain and numbness in lower extremities for 30 years.She was diagnosed with L4 and L5 spondylolisthesis,spinal stenosis,and osteoporosis.The patient underwent spinal canal decompression,an interbody fusion of L4/5 and L5/S1,cement-augmented pedicle screw instrumentation in L4-L5 segments,and regular pedicle screw in S1 segments.Three days postoperatively,a sudden drop in oxygen saturation occurred.Computerized tomography scan confirmed Intracardiac,pulmonary,and intravenous embolism.The patient was treated conservatively by continuous low-flow oxygen inhalation,anti-coagulation,and antibiotic therapy for 1 mo and continued anticoagulation treatment for 6 mo.The patient showed no further symptoms in a 30-mo follow-up.CONCLUSION Intracardiac,pulmonary cement embolism after cement-augmented pedicle screw instrumentation is extremely rare.Careful clinical and radiographic evaluation is required in multiple sites of bone cement embolism.Conservative treatment may be a primary consideration in scattered emboli without life-threatening conditions,but a clinical decision should be made on an individualized basis.展开更多
BACKGROUND Magnetically controlled growing rods(MCGR) are a novel treatment option for early onset scoliosis(EOS). Although the complication profile with MCGR use has been reviewed, these reviews do not take into acco...BACKGROUND Magnetically controlled growing rods(MCGR) are a novel treatment option for early onset scoliosis(EOS). Although the complication profile with MCGR use has been reviewed, these reviews do not take into account important implants modifications, termed iterations, that were made due to early on postoperative complications is not well reported or understood.AIM To assess the effect of MCGR implant iterations on post-operative complications in EOS.METHODS A systematic review was performed to identify studies investigating MCGR specifically for the treatment of EOS, refined to those reporting the implant iteration, specifically the incorporation of the keeper plate to the implant design.Articles with mixed implant iteration usage were excluded. Complications following surgery were recorded as well as potential risk factors and compared between implant cohorts.RESULTS Although 20 articles were identified for inclusion, 5 included mixed implant iteration leaving a total of 271 patients identified through 15 clinical studies thatmet inclusion criteria. The average follow-up was 25.4-mo. Pre-keeper plate implants were utilized in 3 studies with a total of 49 patients. Overall, 115(42.4%)post-operative complications were identified, with 87% defined as major. The addition of the keeper plate significantly decreased the rate of post-operative complications per study(35.7% vs 80.6%, P = 0.036), and the rate of distraction failure(8.1% vs 40.8%, P = 0.02). Unplanned reoperation occurred in 69(26.7%)patients but was not different between implant iteration cohorts(25.5% without keeper plate vs 27.1% with keeper plate, P = 0.92).CONCLUSION MCGR for EOS has a cumulative complication rate of 42.4% but this is significantly reduced to 35.7% when reviewing only keeper-plate enabled implants. However, 25% of published articles included mixed implant iterations.Future studies should discern between implants iterations when reporting on the usage of MCGR for EOS.展开更多
基金Supported by AI For Spinal Surgery Planning and Results Assessment Project under the“Priority 2030”Academic Leadership Initiative,No.6.18-01/240724-15.
文摘BACKGROUND Pedicle screw fixation is frequently used to treat unstable thoracolumbar injuries;however,the rate of instrumentation failure remains considerable.The primary contributing factor leading to instrumentation failure is poor bone quality.On the other hand,some evidence suggests that surgical tactics can influence long-term instrumentation stability.AIM To assess factors that influence the stability of spinal instrumentation in patients with thoracolumbar injuries.METHODS This study is a non-randomized single center ambispective evaluation of 204 consecutive patients(117 men;87 women)with unstable thoracolumbar injuries.All patients underwent either stand-alone or combined with anterior column reconstruction instrumentation.In cases with spinal cord and nerve root injuries,either posterior or anterior decompression were performed.Patients with pedicle screw loosening were identified via computed tomography imaging.Out of those,cases with clinically significant instrumentation failure were registered.RESULTS The rate of pedicle screw loosening detected by computed tomography was inversely correlated with bone radiodensity figures and an increased association with the number of instrumented levels,residual kyphotic deformity,laminectomy,and lumbosacral fixation.Intermediate screws and anterior reconstruction were associated with a clinically relevant decreased risk of pedicle screw loosening development.Either complete or partial posterior fusion within instrumented levels was capable of decreasing instrumentation failure risk,while extensive decompression with laminectomy and at least one-level total facetectomy were associated with an increased risk of instrumentation failure.Anterior decompression does not have a negative impact on instrumentation stability.CONCLUSION Intermediate screws,anterior reconstruction and posterior tension band preservation are associated with decreased rates of instrumentation instability development.Posterior fusion is beneficial in terms of instrumentation failure prevention.
基金supported by the Central Government Guidance Funds for Local Science and Technology Development Program(grant no.ZYYD2025ZY21)the Science and Technology Plan Project of the Xinjiang Production and Construction Corps(2023AB036)+1 种基金the Xinjiang Meteorological Bureau High-Level Key Talent Programthe Natural Science Foundation of the Xinjiang Uygur Autonomous Region(2023D01A17 and 2025D01A109).
文摘Low-visibility phenomena strongly impact the environment,as well as transportation,aviation and other fields that are closely related to people's livelihoods;thus,they represent important ecological issues of social concern.Based on observation data concerning low-visibility phenomena derived from 105 national meteorological stations in Xinjiang,China over the past 20 years,we systematically analyzed the differences between manual and instrument observations for six types of low-visibility phenomena,with a focus on exploring their spatiotemporal distribution characteristics using instrument data.The results revealed that low-visibility phenomena were dominated by fog-and haze-related events(mist,fog,and haze)in northern Xinjiang and dust-related events(dust storms,blowing sand,and floating dust)in southern Xinjiang,with transitional characteristics observed in eastern Xinjiang.Compared with manual observations,the instrument measurements significantly improved the fine-scale low-visibility phenomenon identification process.On the basis of the instrument observation data,spatial-dimension analysis results indicated that low-visibility phenomena in Xinjiang were significantly influenced by terrain factors.Constrained by the Tianshan Mountains,haze-like phenomena formed a core agglomeration area in northern Xinjiang,whereas dust-and sand-related phenomena radiated outward,with the Taklimakan Desert at the center.Moreover,the gripping effect of the terrain promoted dust transmission along low-altitude channels.Temporally,fog-and haze-related phenomena occurred mainly during autumn and winter,and the proportion of these events decreased from 76.7%to 55.1%.The fog-and haze-related phenomena demonstrated a U-shaped rebound trend,while the proportion of mist phenomena decreased by 34.2%.Dust storms occurred during spring,accounting for 23.3%to 44.9%of all storms.Instrument measurement technology has the advantages of high spatial and temporal resolutions and multiparameter coordination but provides a limited dust-haze mixed-pollution identification capacity.This study provides crucial reference data for enhancing the understanding of low-visibility events in Xinjiang and the potential responses while improving the accuracy of pollution source tracking and meteorological process diagnosis tasks.
基金Management Research Project on the Transformation of Scientific and Technological Achievements at Peking University Health Science Center(Grant No.KT202501)Peking University Health Science Center 2025 Party Building Research Project(General Category,No.2)。
文摘Scientific instruments serve as foundational pillars for both scientific progress and industrial innovation,enabling deep exploration and driving technological breakthroughs.Their independent controllability and continuous innovation are indispensable for sustaining a competitive advantage in technological development,thereby securing national scientific capacity and long-term strategic growth.At present,however,China faces substantial risks of technological"stranglehold"in the high-end scientific instrument domain.The underlying causes are multifaceted,arising not only from insufficient accumulation of core technologies but also from entrenched systemic and ecosystem-level barriers that impede the application,scaling,and promotion of domestic instruments.This paper provides a systematic analysis of the challenges hindering the widespread adoption of domestically developed scientific instruments and proposes practical pathways to build a new,integrated"R&D-application-promotion"ecosystem.This ecosystem is anchored in trust,driven by user demand,and shaped through collaborative innovation.Key initiatives include organizing user visits to instrument manufacturers,convening seminars on domestic alternatives to imported equipment,establishing demonstration centers for application and promotion,and involving end-users directly in the R&D and iterative upgrading of domestic instruments.Together,these efforts aim to close the final critical gap,advancing domestic instruments from merely"functional"to genuinely"user-friendly",and ultimately to"widely implemented".By doing so,this framework offers both theoretical grounding and practical guidance for achieving high-level scientific and technological self-reliance and sustained innovation capacity.
文摘Chinese video game Black Myth:Wukong has been a h it among gaming enthusiasts worldwide since its release in 2024, its breakout success demonstrating the potential global appeal of traditional Chinese culture. Based on the 16th-century classic novel Journey to the West, the game not only introduces international audiences to Chinese literature but has also become a far-reaching platform for traditional Chinese music.
文摘AIM: To summarise and compare currently available evidence regarding accuracy of pre-operative imaging, which is one of the key choices for surgeons contemplating patient-specific instrumentation(PSI) surgery.METHODS: The MEDLINE and EMBASE medical literature databases were searched, from January 1990 to December 2013, to identify relevant studies. The data from several clinical studies was assimilated to allow appreciation and comparison of the accuracy of each modality. The overall accuracy of each modality was calculated as proportion of outliers > 3% in the coronal plane of both computerised tomography(CT) or magnetic resonance imaging(MRI). RESULTS: Seven clinical studies matched our inclusion criteria for comparison and were included in our study for statistical analysis. Three of these reported series using MRI and four with CT. Overall percentage of outliers > 3% in patients with CT-based PSI systems was 12.5% vs 16.9% for MRI-based systems. These results were not statistically significant. CONCLUSION: Although many studies have been undertaken to determine the ideal pre-operative imaging modality, conclusions remain speculative in the absence of long term data. Ultimately, information regarding accuracy of CT and MRI will be the main determining factor. Increased accuracy of pre-operative imaging could result in longer-term savings, and reduced accumulated dose of radiation by eliminating the need for post-operative imaging and revision surgery.
文摘Patient specific instrumentation(PSI) in total knee arthroplasty(TKA) promises faster operation time(by using less instruments and individual cutting jigs), less blood loss, faster rehabilitation, better implant sizing and accuracy, superior overall outcome, and at the end- less costs. However, as evident for every new development, its superiority remains to be provenover the conventional systems. Whilst dissatisfaction is reported to be eminent in up to 30% of patients having undergone conventional TKA, it is unclear, whether PSI can address to these patients as a suitable option in the future. The author believes that the current evidence does not support superiority of PSI in TKA over conventional systems. However, future long-term level I and II studies might aid to show its cost-effectiveness stating same results, accuracy, and overall outcome with less operation time.
文摘In this study,the behavior of Gavoshan dam was evaluated during construction and the first impounding.A two-dimensional（2D） numerical analysis was conducted based on a finite difference method on the largest cross-section of the dam using the results of instrument measurements and back analysis.These evaluations will be completed in the case that back analysis is carried out in order to control the degree of the accuracy and the level of confidence of the measured behavior since each of the measurements could be controlled by comparing it to the result obtained from the numerical model.Following that,by comparing the results of the numerical analysis with the measured values,it is indicated that there is a proper consistency between these two values.Moreover,it was observed that the dam performance was suitable regarding the induced pore water pressure,the pore water pressure ratio r;,settlement,induced stresses,arching degree,and hydraulic fracturing probability during the construction and initial impounding periods.The results demonstrated that the maximum settlement of the core was 238 cm at the end of construction.In the following 6 years after construction（initial impounding and exploitation period）,the accumulative settlement of the dam was 270 cm.It is clear that 88% of the total settlement of the dam took place during dam construction.The reason is that the clay core was smashed in the wet side,i.e.the optimum moisture content.Whereas the average curving ratio was 0.64 during dam construction; at the end of the initial impounding,the maximum amount of curving ratio in the upstream was 0.81,and the minimum（critical） amount in the downstream was 0.52.It was also concluded that this dam is safe in comparison with the behaviors of other similar dams in the world.
基金Project 2007E237 supported by the Science Fund Program of Shaanxi Province of China
文摘Ventilation fans are one of the most important pieces of equipment in coal mines. Their performance plays an important role in the safety of staff and production. Given the actual requirements of coal mine production,we instituted a research project on the measurement methods of key performance parameters such as wind pressure,amount of ventilation and power. At the end a virtual instrument for mine ventilation fans performance evaluation was developed using a USB interface. The practical performance and analytical results of our experiments show that it is feasible,reliable and effective to use the proposed instrumentation for mine ventilation performance evaluation.
基金supported by Ministry of Science and Technology(MOST)instrumentation program of China(No.2012YQ04014007)National Natural Science Foundation of China(NSF)(No.21475010)+1 种基金Beijing Natural Science Foundation(BNSF)(No.16L00065)State Key Laboratory Explosion Science and Technology(No.YBKT16-17)
文摘Capillary electrophoresis-mass spectrometry（CE-MS） is a powerful separation and analytical technique in the field of analytical chemistry. This review provides an update of instrumentation developments in the methodology of CE-MS systems. A selection of relevant articles covers the literatures published from Jan. 2013 to Feb. 2017. Special attentions were paid to the sample injection and ionization processes.Applications of these CE-MS systems were also introduced through representative examples. General conclusions and perspectives were given at the last.
文摘Pelvic instrumentation for neuromuscular scoliosis has been part of neuromuscular scoliosis surgery since the era of the Luque Galveston construct. Unit Rod(Medtronic Sofamor-Danek, Nashville, TN) instrumentation brought with it the concept of cantilever correction by placing the implants in the pelvis and then gradually bringing the rod to the spine by sequentially tightening the sublaminar wires, with the goal of creating a level pelvis over a straight spine. More recently surgeons have utilized pedicle screw constructs in which the corrective strategies have varied. Challenges with pelvic fixation using iliac screws linked to the spinal rod have led to the development of the S2-alariliac technique(S2 AI) in which the spinal rod connects to the pelvic screw. The screw is placed in the S2 ala, crosses the sacro-iliac joint and into the ilium through a large column of supra-acetabular bone. This column is the same area used for anterior inferior iliac spine external fixation frames used in trauma surgery. S2 AI screw placement can be technically difficult and can require experienced radiology technologists to provide the appropriate views. Additionally, although the technique was originally described being placed via freehand technique with intra-operative flouroscopy, the freehand technique suffers from the anatomic anomalies present in the pelvis in neuromuscular scoliosis. As such, we prefer to place them using intra-operative navigation for all pediatric spinal deformity cases. Below in detail we report our intra-operative technique and an illustrative case example.
基金the USTC Research Funds of the Double First-Class Initiative(No.YD2080002006)。
文摘Seismic networks have significantly improved in the last decade in terms of coverage density,data quality,and instrumental diversity.Moreover,revolutionary advances in ultra-dense seismic instruments,such as nodes and fiber-optic sensing technologies,have recently provided unprecedented high-resolution data for regional and local earthquake monitoring.Nodal arrays have characteristics such as easy installation and flexible apertures,but are limited in power efficiency and data storage and thus most suitable as temporary networks.Fiber-optic sensing techniques,including distributed acoustic sensing,can be operated in real time with an in-house power supply and connected data storage,thereby exhibiting the potential of becoming next-generation permanent networks.Fiber-optic sensing techniques offer a powerful way of filling the observation gap particularly in submarine environments.Despite these technological advancements,various challenges remain.First,the data characteristics of fiber-optic sensing are still unclear.Second,it is challenging to construct software infrastructures to store,transfer,visualize,and process large amount of seismic data.Finally,innovative detection methods are required to exploit the potential of numerous channels.With improved knowledge about data characteristics,enhanced software infrastructures,and suitable data processing techniques,these innovations in seismic instrumentation could profoundly impact observational seismology.
文摘BACKGROUND Over the past years,patient specific instrumentation(PSI)for total knee arthroplasty(TKA)has been implemented and routinely used.No clear answer has been given on its associated cost and cost-effectiveness when compared to conventional instrumentation(CI)for TKA.AIM To compare the cost and cost-effectiveness of PSI TKA compared to CI TKA.METHODS A literature search was performed in healthcare,economical healthcare,and medical databases(MEDLINE,EMBASE,CINAHL,Web of Science,Cochrane Library,EconLit).It was conducted in April 2021 and again in January 2022.Relevant literature included randomised controlled trials,retrospective studies,prospective studies,observational studies,and case control studies.All studies were assessed on methodological quality.Relevant outcomes included incremental cost-effectiveness ratio,quality-adjusted life years,total costs,imaging costs,production costs,sterilization associated costs,surgery duration costs and readmission rate costs.All eligible studies were assessed for risk of bias.Meta-analysis was performed for outcomes with sufficient data.RESULTS Thirty-two studies were included into the systematic review.Two were included in the metaanalysis.3994 PSI TKAs and 13267 CI TKAs were included in the sample size.The methodological quality of the included studies,based on Consensus on Health Economic Criteria-scores and risk of bias,ranged from average to good.PSI TKA costs less than CI TKA when considering mean operating room time and its associated costs and tray sterilization per patient case.PSI TKA costs more compared to CI TKA when considering imaging and production costs.Considering total costs per patient case,PSI TKA is more expensive in comparison to CI TKA.Meta-analysis comparing total costs for PSI TKA,and CI TKA showed a significant higher cost for PSI TKA.CONCLUSION Cost for PSI and CI TKA can differ when considering distinct aspects of their implementation.Total costs per patient case are increased for PSI TKA when compared to CI TKA.
文摘Objective. To introduce a new spinal internal fixation system, Texas Scottish Rite Hospital (TSRH), and to investigate its early clinical outcomes.Methods. The preliminary clinical outcomes of 15 patients with thoracolumbar or lumbar scoliosis treated by anterior spinal fusion with TSRH instrumentation were studied retrospectively. Fourteen patients were diagnosed as idiopathic scoliosis and 1 as neuromuscular scoliosis.Results. Preoperatively, the Cobb's angle on the coronal plane was 55. 8° (range 35° - 78°), and 14° postoperatively, with an average correction of 74. 8 %. The average unfused thoracical curve was 35. 9 ° preoperatively (range 26° - 51°) and 21. 8° (10°-42° ) postoperatively, with 40% correction. The sagittal curve of lumbar was kept physiologically, preoperative 27. 9° and postoperative 25. 7° respectively. The trunk shift was 13.4 mm (5 - 28mm) preoperatively and 3. 5 mm (0-7 mm) postoperatively. The averaged apic vertebra derivation was 47. 8 mm (21 - 69 mm) before operation and 10. 8 mm (3-20 mm) after operation. The distance of C7 to center sacrum vertical line (CSVL) was 19. 5 mm(16 - 42)preoperatively and 11. 3 mm (0-32 mm) postoperatively. The apical vertebra rotation was 3 degree in 15 patients preoperatively, and were improved to normal in 10 patients, 1 degree in 4 patients, and 2 degree in 1 patients postoperatively. None had neurological injury and infection. Only 1 patient complained a cool feeling in the low extremity of concave side, and the symptom vanished at 3-month followed up.Conclusion. If used appropriately, TSRH anterior spinal system is a good treatment for low thoracic or thoracic lumbar scoliosis.
文摘Objective. To evaluate the results of TSRH instrumentation in the correction of coronal, sagittal and rotational deformity of scoliosis. Methods. From January 1998 to December 1999, thirty- two consecutive patients (6 males, 26 females) with scoliosis underwent anterior or posterior spinal instrumentation and fusion using TSRH instrumentation. Of these cases, 21 were idiopathic scoliosis and 11 were congenital scoliosis. The average age at surgery was 16.4 years (range, 11～ 45 years). The mean Cobb angle at surgery was 71 .2 (range, 44～ 125 ) in the coronal plane, and 49.2 ( range, 16～ 67 ) in the sagittal plane. Rotational deformity (Nash- Moe) ranged from I to III degree. Preoperative apical translation averaged 4.8 cm (range, 3～ 9 cm). Results. The average follow- up duration was 13.3 months (range, 10～ 24 months).At the final follow- up, the mean Cobb angle in the coronal plane was 26. 6 (range, 10～ 73 ),with a 63.8％ of improvement. Sagittal alignment was well maintained with a mean Cobb angle of 28 ( range, 10～ 45 ). The average correction of rotation of the apical vertebra was I degree. The average apical translation was 1.6 cm (range, 0.5～ 5.0 cm) representing a correction rate of 66,7％ . Complication was noted in two cases with an incidence of 3.1％ , one case had superficial infection and the other one had lower hook dislocation.There was no neurologic deficit and pseudoarthrodesis in this series. Conclusion. TSRH instrumentation is an effective and convenient three- dimensional correction system with a lower rate of complication, which can not only correct the coronal and rotational deformity, but maintain the sagittal alignment as well.
文摘The recent increase in the adoption of total ankle arthroplasty(TAA)reflects the improvements in implant designs and surgical techniques,including the use of preoperative navigation system and patient-specific instrumentation(PSI),such as custom-made cutting guides.Cutting guides are customized with respect to each patient's anatomy based on preoperative ankle computed tomography scans,and they drive the saw intra-operatively to improve the accuracy of bone resection and implant positioning.Despite some promising results,the main queries in the literature are whether PSI improves the reliability of achieving neutral ankle alignment and more accurate implant sizing,whether it is actually superior over standard techniques,and whether it is cost effective.Moreover,the advantages of PSI in clinical outcomes are still theoretical because the current literature does not allow to confirm its superiority.The purpose of this review article is therefore to assess the current literature on PSI in TAA with regard to current implants with PSI,templating and preoperative planning strategies,alignment and sizing,clinical outcomes,cost analysis,and comparison with standard techniques.
文摘-A Portable gas chromatograPhy (GC) instrument is presented in this paper. In this GC instrument a new gaseous sampling device was used in place of conventional sampling valves.It has no quantitative tube or movable components in the sample Path. The sampling size si determined by time with a high precision,which is not sensitive to the sample temperature and pressure.Especially,the sample can not only inject into the column head,but also the carrier gas blow the column reversely and clean it.The portable GC instrument based on the sampling device can be used in enviromental and biomedical monitoring.
基金supported by the Natural Sciences and Engineering Research Council of Canadathe India-Canada Centre of Excellence for Innovative Multidisciplinary Partnership to Accelerate Community Transformation and Sustainability(IC-IMPACTS)research grantsary D.Eng.degree from University of Waterloo,Canada(2008).He has been a Professor of Mechanical Engineering and Senior Canada Research Chair and NSERC-BC Packers Chair in Industrial Automation,at the University of British Columbia,Vancouver,Canada since 1988.He has authored 24 books and about 540 papers,approximately half of which are in joumals.His recent books published by Taylor&Francis/CRC are:Modeling of Dynamic Systems-with Engineering Applications(2018),Sensor Systems(2017),Sensors and Actuators-Engineering System Instrumentation,2nd edition(2016),Mechanics of Materials(2014),Mechatronics-A Foundation Course(2010),Modeling and Control of Engineering Systems(2009),VIBRATION-Fundamentals and Practice,2nd Ed.(2007),and by Addison Wesley:Soft Computing and Intelligent Systems Design-Theory,Tools,and Applications(with F.Karray,2004).Email:desilva@mech.ubc.ca.
文摘This paper deals with instrumenting a mechatronic system,through the incorporation of suitable sensors,actuators,and other required hardware.Sensors(e.g.,semiconductor strain gauges,tachometers,RTD temperature sensors,cameras,piezoelectric accelerometers)are needed to measure(sense)unknown signals and parameters of a system and its environment.The information acquired in this manner is useful in operating or controlling the system,and also in process monitoring;experimental modeling(i.e.,model identification);product testing and qualification;product quality assessment;fault prediction,detection and diagnosis;warning generation;surveillance,and so on.Actuators(e.g.,stepper motors,solenoids,dc motors,hydraulic rams,pumps,heaters/coolers)are needed to"drive"a plant.Control actuators(e.g.,control valves)perform control actions,and in particular they drive control devices.Micro-electromechanical systems(MEMS)use microminiature sensors and actuators.MEMS sensors commonly use piezoelectric,capacitive,electromagnetic and piezoresistive principles.MEMS devices provide the benefits of small size and light weight(negligible loading errors),high speed(high bandwidth),and convenient mass-production(low cost).The process of instrumentation involves the identification of proper sensors,actuators,controllers,signal modification/interface hardware,and software with respect to their functions,operation,parameters,ratings,interaction with each other,so as to achieve the performance requirements of the overall system,and interfacing/integration/tuning of the selected devices into the system,for a given application.This paper presents the key steps of instrumenting a mechatronic system,in a somewhat general and systematic manner.Examples are described to illustrate several key procedures of instrumentation.
基金The Center for Risk-Based Community Resilience Planning is a NIST-funded Center of Excellencethe Center is funded through a cooperative agreement between the U.S.National Institute of Standards and Tech-nology and Colorado State University(NIST Financial Assistance Award Numbers:70NANB15H044 and 70NANB20H008)。
文摘In 2015,the U.S National Institute of Standards and Technology(NIST)funded the Center of Excellence for Risk-Based Community Resilience Planning(CoE),a fourteen university-based consortium of almost 100 col-laborators,including faculty,students,post-doctoral scholars,and NIST researchers.This paper highlights the scientific theory behind the state-of-the-art cloud platform being developed by the CoE-the Interdisciplinary Networked Community Resilience Modeling Environment(IN-CORE).IN-CORE enables communities,consul-tants,and researchers to set up complex interdependent models of an entire community consisting of people,businesses,social institutions,buildings,transportation networks,water networks,and electric power networks and to predict their performance and recovery to hazard scenario events,including uncertainty propagation through the chained models.The modeling environment includes a detailed building inventory,hazard scenario models,building and infrastructure damage(fragility)and recovery functions,social science data-driven house-hold and business models,and computable general equilibrium(CGE)models of local economies.An important aspect of IN-CORE is the characterization of uncertainty and its propagation throughout the chained models of the platform.Three illustrative examples of community testbeds are presented that look at hazard impacts and recovery on population,economics,physical services,and social services.An overview of the IN-CORE technology and scientific implementation is described with a focus on four key community stability areas(CSA)that encompass an array of community resilience metrics(CRM)and support community resilience informed decision-making.Each testbed within IN-CORE has been developed by a team of engineers,social scientists,urban planners,and economists.Community models,begin with a community description,i.e.,people,businesses,buildings,infras-tructure,and progresses to the damage and loss of functions caused by a hazard scenario,i.e.,a flood,tornado,hurricane,or earthquake.This process is accomplished through chaining of modular algorithms,as described.The baseline community characteristics and the hazard-induced damage sets are the initial conditions for the recovery models,which have been the least studied area of community resilience but arguably one of the most important.Communities can then test the effect of mitigation and/or policies and compare the effects of“what if”scenarios on physical,social,and economic metrics with the only requirement being that the change much be able to be numerically modeled in IN-CORE.
基金Fundamental Research Funds for the Central Universities,No.20ykpy94.
文摘BACKGROUND We report a case of Intracardiac,pulmonary,and intravenous cement embolism after cement-augmented pedicle screw instrumentation in treating spondylolisthesis underlying osteoporotic bone,which was successfully managed by conservative treatment.We describe the treatment and outcome of the patient,hoping to shed light on the management of bone cement embolism.CASE SUMMARY A 67-year-old female suffered from progressive low back pain and numbness in lower extremities for 30 years.She was diagnosed with L4 and L5 spondylolisthesis,spinal stenosis,and osteoporosis.The patient underwent spinal canal decompression,an interbody fusion of L4/5 and L5/S1,cement-augmented pedicle screw instrumentation in L4-L5 segments,and regular pedicle screw in S1 segments.Three days postoperatively,a sudden drop in oxygen saturation occurred.Computerized tomography scan confirmed Intracardiac,pulmonary,and intravenous embolism.The patient was treated conservatively by continuous low-flow oxygen inhalation,anti-coagulation,and antibiotic therapy for 1 mo and continued anticoagulation treatment for 6 mo.The patient showed no further symptoms in a 30-mo follow-up.CONCLUSION Intracardiac,pulmonary cement embolism after cement-augmented pedicle screw instrumentation is extremely rare.Careful clinical and radiographic evaluation is required in multiple sites of bone cement embolism.Conservative treatment may be a primary consideration in scattered emboli without life-threatening conditions,but a clinical decision should be made on an individualized basis.
文摘BACKGROUND Magnetically controlled growing rods(MCGR) are a novel treatment option for early onset scoliosis(EOS). Although the complication profile with MCGR use has been reviewed, these reviews do not take into account important implants modifications, termed iterations, that were made due to early on postoperative complications is not well reported or understood.AIM To assess the effect of MCGR implant iterations on post-operative complications in EOS.METHODS A systematic review was performed to identify studies investigating MCGR specifically for the treatment of EOS, refined to those reporting the implant iteration, specifically the incorporation of the keeper plate to the implant design.Articles with mixed implant iteration usage were excluded. Complications following surgery were recorded as well as potential risk factors and compared between implant cohorts.RESULTS Although 20 articles were identified for inclusion, 5 included mixed implant iteration leaving a total of 271 patients identified through 15 clinical studies thatmet inclusion criteria. The average follow-up was 25.4-mo. Pre-keeper plate implants were utilized in 3 studies with a total of 49 patients. Overall, 115(42.4%)post-operative complications were identified, with 87% defined as major. The addition of the keeper plate significantly decreased the rate of post-operative complications per study(35.7% vs 80.6%, P = 0.036), and the rate of distraction failure(8.1% vs 40.8%, P = 0.02). Unplanned reoperation occurred in 69(26.7%)patients but was not different between implant iteration cohorts(25.5% without keeper plate vs 27.1% with keeper plate, P = 0.92).CONCLUSION MCGR for EOS has a cumulative complication rate of 42.4% but this is significantly reduced to 35.7% when reviewing only keeper-plate enabled implants. However, 25% of published articles included mixed implant iterations.Future studies should discern between implants iterations when reporting on the usage of MCGR for EOS.
