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An Improved Artificial Immune Algorithm with a Dynamic Threshold 被引量:5
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作者 Zhang Qiao Xu Xu Liang Yan-chun 《Journal of Bionic Engineering》 SCIE EI CSCD 2006年第2期93-97,共5页
An improved artificial immune algorithm with a dynamic threshold is presented. The calculation for the affinity function in the real-valued coding artificial immune algorithm is modified through considering the antib... An improved artificial immune algorithm with a dynamic threshold is presented. The calculation for the affinity function in the real-valued coding artificial immune algorithm is modified through considering the antibody's fitness and setting the dynamic threshold value. Numerical experiments show that compared with the genetic algorithm and the originally real-valued coding artificial immune algorithm, the improved algorithm possesses high speed of convergence and good performance for preventing premature convergence. 展开更多
关键词 dynamic threshold artificial immune algorithm genetic algorithm ANTIBODY
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Learning Bayesian network structure with immune algorithm 被引量:4
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作者 Zhiqiang Cai Shubin Si +1 位作者 Shudong Sun Hongyan Dui 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2015年第2期282-291,共10页
Finding out reasonable structures from bulky data is one of the difficulties in modeling of Bayesian network (BN), which is also necessary in promoting the application of BN. This pa- per proposes an immune algorith... Finding out reasonable structures from bulky data is one of the difficulties in modeling of Bayesian network (BN), which is also necessary in promoting the application of BN. This pa- per proposes an immune algorithm based method (BN-IA) for the learning of the BN structure with the idea of vaccination. Further- more, the methods on how to extract the effective vaccines from local optimal structure and root nodes are also described in details. Finally, the simulation studies are implemented with the helicopter convertor BN model and the car start BN model. The comparison results show that the proposed vaccines and the BN-IA can learn the BN structure effectively and efficiently. 展开更多
关键词 structure learning Bayesian network immune algorithm local optimal structure VACCINATION
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Distance Concentration-Based Artificial Immune Algorithm 被引量:6
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作者 LIUTao WANGYao-cai +1 位作者 WANGZhi-jie MENGJiang 《Journal of China University of Mining and Technology》 EI 2005年第2期81-85,共5页
The diversity, adaptation and memory of biological immune system attract much attention of researchers. Several optimal algorithms based on immune system have also been proposed up to now. The distance concentra- tion... The diversity, adaptation and memory of biological immune system attract much attention of researchers. Several optimal algorithms based on immune system have also been proposed up to now. The distance concentra- tion-based artificial immune algorithm (DCAIA) is proposed to overcome defects of the classical artificial immune al- gorithm (CAIA) in this paper. Compared with genetic algorithm (GA) and CAIA, DCAIA is good for solving the prob- lem of precocity,holding the diversity of antibody, and enhancing convergence rate. 展开更多
关键词 artificial immune system distance concentration immune algorithm
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A new artificial immune algorithm and its application for optimization problems 被引量:1
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作者 于志刚 宋申民 段广仁 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2006年第2期129-133,共5页
A new artificial immune algorithm (AIA) simulating the biological immune network system with selfadjustment function is proposed in this paper. AIA is based on the modified immune network model in which two methods ... A new artificial immune algorithm (AIA) simulating the biological immune network system with selfadjustment function is proposed in this paper. AIA is based on the modified immune network model in which two methods of affinity measure evaluated are used, controlling the antibody diversity and the speed of convergence separately. The model proposed focuses on a systemic view of the immune system and takes into account cell-cell interactions denoted by antibody affinity. The antibody concentration defined in the immune network model is responsible directly for its activity in the immune system. The model introduces not only a term describing the network dynamics, but also proposes an independent term to simulate the dynamics of the antigen population. The antibodies' evolutionary processes are controlled in the algorithms by utilizing the basic properties of the immune network. Computational amount and effect is a pair of contradictions. In terms of this problem, the AIA regulating the parameters easily attains a compromise between them. At the same time, AIA can prevent premature convergence at the cost of a heavy computational amount (the iterative times). Simulation illustrates that AIA is adapted to solve optimization problems, emphasizing muhimodal optimization. 展开更多
关键词 artificial immune network optimization algorithm preventing premature convergence.
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Adaptive immune-genetic algorithm for global optimization to multivariable function 被引量:9
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作者 Dai Yongshou Li Yuanyuan +2 位作者 Wei Lei Wang Junling Zheng Deling 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2007年第3期655-660,共6页
An adaptive immune-genetic algorithm (AIGA) is proposed to avoid premature convergence and guarantee the diversity of the population. Rapid immune response (secondary response), adaptive mutation and density opera... An adaptive immune-genetic algorithm (AIGA) is proposed to avoid premature convergence and guarantee the diversity of the population. Rapid immune response (secondary response), adaptive mutation and density operators in the AIGA are emphatically designed to improve the searching ability, greatly increase the converging speed, and decrease locating the local maxima due to the premature convergence. The simulation results obtained from the global optimization to four multivariable and multi-extreme functions show that AIGA converges rapidly, guarantees the diversity, stability and good searching ability. 展开更多
关键词 immune-genetic algorithm function optimization hyper-mutation density operator.
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Mongolian Similar Elements Clustering via Immune Clone Algorithm
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作者 Chunhua Chao ZHANG +1 位作者 Yan LIU Wei WU 《Journal of Mathematical Research with Applications》 CSCD 2019年第6期745-754,共10页
Text clustering is an important research issue of clustering technique. It aims to use the similar characteristics or similar expression to group the text so that the texts in the same clusters have the greatest simil... Text clustering is an important research issue of clustering technique. It aims to use the similar characteristics or similar expression to group the text so that the texts in the same clusters have the greatest similarity, and those in different clusters have the greatest dissimilarity.There are many characteristics in Mongolian structure and writing-mode compared with other kinds of characters. By combining K-means and clone immune algorithm, we propose a novel clustering technique called ICKM. Numerical experiments on four elements sets illustrate the validity of our method in the clustering task for Mongolian. 展开更多
关键词 immune CLONE algorithm MONGOLiaN similar ELEMENTS CLUSTERING K-MEANS
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ARTIFICIAL IMMUNE ALGORITHM OF MULTICELLULAR GROUP AND ITS CONVERGENCE
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作者 罗印升 李人厚 张维玺 《Journal of Pharmaceutical Analysis》 SCIE CAS 2005年第2期23-27,共5页
Objective To find out more extrema simultaneously including global optimum and multiple local optima existed in multi-modal functions. Methods Germinal center is the generator and selector of high-affinity B cells, a ... Objective To find out more extrema simultaneously including global optimum and multiple local optima existed in multi-modal functions. Methods Germinal center is the generator and selector of high-affinity B cells, a multicellular group's artificial immune algorithm was proposed based on the germinal center reaction mechanism of natural immune systems. Main steps of the algorithm were given, including hyper-mutation, selection, memory, similarity suppression and recruitment of B cells and the convergence of it was proved. Results The algorithm has been tested to optimize various multi-modal functions, and the simulation results show that the artificial immune algorithm proposed here can find multiple extremum of these functions with lower computational cost. Conclusion The algorithm is valid and can converge on the satisfactory solution set D with probability 1 and approach to global solution and many local optimal solutions existed. 展开更多
关键词 germinal center reaction B cell artificial immune algorithm multi-modal function
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维奈克拉联合IA方案对AML患者疗效、免疫功能、生活质量、不良反应及生存期的影响
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作者 李嘉 张明明 《牡丹江医科大学学报》 2025年第2期55-60,共6页
目的观察维奈克拉联合IA方案(去甲氧柔红霉素+阿糖胞苷)对急性髓系白血病(acute myeloidleukemia,AML)患者疗效、T淋巴细胞免疫变化、生活质量改善情况、不良反应及1年期生存期的影响,并查阅相关文献探讨其作用机制。方法选取安徽省宿... 目的观察维奈克拉联合IA方案(去甲氧柔红霉素+阿糖胞苷)对急性髓系白血病(acute myeloidleukemia,AML)患者疗效、T淋巴细胞免疫变化、生活质量改善情况、不良反应及1年期生存期的影响,并查阅相关文献探讨其作用机制。方法选取安徽省宿州市第一人民医院血液科于2021年06月至2023年06月期间收治的82例AML(非M3型)患者,依据用药方法分随机为IA组(n=41,接受去甲氧柔红霉素+阿糖胞苷治疗)和VIA组(n=41,接受维奈克拉+去甲氧柔红霉素+阿糖胞苷治疗),两组患者均治疗1个疗程(28 d/疗程)。比较两组患者治疗后客观缓解率及微小残留病(MRD)转阴率;治疗前后T淋巴细胞免疫变化、生活质量(KPS评分)改善情况及不良反应;随访1年后的无进展生存期(PFS)和总生存期(OS)。结果(1)VIA组客观缓解率为85.37%,MRD转阴率为58.54%,均高于IA组的73.17%、43.90%,组间比较均存有显著差异(P<0.05);(2)治疗前免疫功能指标组间无明显差异(P>0.05),治疗后两组CD3^(+)、CD4^(+)、CD8^(+)均上升,但VIA组上升幅度高于IA组,组间比较差异具有统计学意义(P<0.05);(3)治疗前两组KPS评分无统计学意义(P>0.05),治疗后VIA组KPS评分高达(86.08±10.93)分,而IA组低至(79.36±12.35)分,组间比较可见明显差异(P<0.05);(4)VIA组和IA组血液学相关不良反应分别为95.12%、85.37%,非血液学相关不良反应分别为92.68%、78.05%,VIA组虽略高,但组间比较并不存在显著差异(P>0.05);(5)1年后随访发现,两组患者PFS及OS比较均存在明显差异(log rank x^(2)=8.157,4.216,P<0.05)。结论VIA(维奈克拉联合IA方案)方案应用于AML(非M3型)总体疗效优于IA方案,可有效提升客观缓解率及MRD转阴率、改善机体免疫功能和生活质量、提高PFS和OS,而安全性则同IA方案无异,有较高的临床推广价值。 展开更多
关键词 维奈克拉 ia方案 AML 疗效 免疫功能 生活质量 不良反应
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Lake Eutrophic Evaluation Based on Bee Immune Evolutionary Algorithm 被引量:1
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作者 党媛 李祚泳 邹艳玲 《Agricultural Science & Technology》 CAS 2010年第4期156-158,188,共4页
In order to establish the lake eutrophic evaluation model for multiple indices,based on the gauge transformation,an index formula in the form of a logarithmic power function was proposed to design an eutrophic evaluat... In order to establish the lake eutrophic evaluation model for multiple indices,based on the gauge transformation,an index formula in the form of a logarithmic power function was proposed to design an eutrophic evaluation model for the " normalized values" of multi-indexes.The parameters in the formula were also optimized by bee immune evolutionary algorithm(BEIEA).The universal index formula was suitable to multiindices items for eutrophic evaluation.At the same time,the formula was applied to practical eutrophic evaluations in 10 regions of Dong Lake.The evaluation results were coincident with those obtained from the power function of weighted sums and also with actual conditions.It was shown that the bee immune evolutionary algorithm was suitable to the parameter optimization in the eutrophic evaluation model. 展开更多
关键词 LAKE Eutrophic evaluation Bee algorithm Bee immune evolutionary algorithm Parameter optimization
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OPTIMIZATION OF AIRPORT TAXIING PLANNING DURING CONGESTED HOURS BASED ON IMMUNE CLONAL SELECTION ALGORITHM 被引量:1
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作者 柳青 吴桐水 宋祥波 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2012年第3期294-301,共8页
In order to ease congestion and ground delays in major hub airports, an aircraft taxiing scheduling optimization model is proposed with schedule time as the object function. In the new model, the idea of a classical j... In order to ease congestion and ground delays in major hub airports, an aircraft taxiing scheduling optimization model is proposed with schedule time as the object function. In the new model, the idea of a classical job shop-schedule problem is adopted and three types of special aircraft-taxi conflicts are considered in the constraints. To solve such nondeterministic polynomial time-complex problems, the immune clonal selection algorithm(ICSA) is introduced. The simulation results in a congested hour of Beijing Capital International Airport show that, compared with the first-come-first-served(FCFS) strategy, the optimization-planning strategy reduces the total scheduling time by 13.6 min and the taxiing time per aircraft by 45.3 s, which improves the capacity of the runway and the efficiency of airport operations. 展开更多
关键词 aircraft taxiing schedule airport operation control hub airport congested hours immune clonal selection algorithm(ICSA)
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Application of an immune algorithm to settlement prediction 被引量:5
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作者 Jia GUO Jun-jie ZHENG Yong LIU 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2009年第1期93-100,共8页
The settlement curve of the foundation endured the ramp load is an S-type curve,which is usually simulated via Poisson curve.Aimed at the difficulty of preferences in Poisson curve,an immune algorithm (IA) is used.IA ... The settlement curve of the foundation endured the ramp load is an S-type curve,which is usually simulated via Poisson curve.Aimed at the difficulty of preferences in Poisson curve,an immune algorithm (IA) is used.IA is able to obtain a multiple quasi-optimum solution while maintaining the population diversity.In this paper,IA is used in an attempt to obtain accurate settlement prediction.The predicted settlements obtained by IA are compared with those predicted by the least squares fitting method (LSM),the Asaoka method and the genetic algorithm (GA).The results show that IA is a useful technique for predicting the settlement of foundations with an acceptable degree of accuracy and has much better performance than GA and the Asaoka methods. 展开更多
关键词 SETTLEMENT PREDICTION FOUNDATION immune algorithm ia
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Reconstruction of Gene Regulatory Networks Based on Two-Stage Bayesian Network Structure Learning Algorithm 被引量:4
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作者 Gui-xia Liu, Wei Feng, Han Wang, Lei Liu, Chun-guang ZhouCollege of Computer Science and Technology, Jilin University, Changchun 130012,P.R. China 《Journal of Bionic Engineering》 SCIE EI CSCD 2009年第1期86-92,共7页
In the post-genomic biology era,the reconstruction of gene regulatory networks from microarray gene expression data is very important to understand the underlying biological system,and it has been a challenging task i... In the post-genomic biology era,the reconstruction of gene regulatory networks from microarray gene expression data is very important to understand the underlying biological system,and it has been a challenging task in bioinformatics.The Bayesian network model has been used in reconstructing the gene regulatory network for its advantages,but how to determine the network structure and parameters is still important to be explored.This paper proposes a two-stage structure learning algorithm which integrates immune evolution algorithm to build a Bayesian network.The new algorithm is evaluated with the use of both simulated and yeast cell cycle data.The experimental results indicate that the proposed algorithm can find many of the known real regulatory relationships from literature and predict the others unknown with high validity and accuracy. 展开更多
关键词 gene regulatory networks two-stage learning algorithm Bayesian network immune evolutionary algorithm
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Fuzzy least squares support vector machine soft measurement model based on adaptive mutative scale chaos immune algorithm 被引量:8
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作者 王涛生 左红艳 《Journal of Central South University》 SCIE EI CAS 2014年第2期593-599,共7页
In order to enhance measuring precision of the real complex electromechanical system,complex industrial system and complex ecological & management system with characteristics of multi-variable,non-liner,strong cou... In order to enhance measuring precision of the real complex electromechanical system,complex industrial system and complex ecological & management system with characteristics of multi-variable,non-liner,strong coupling and large time-delay,in terms of the fuzzy character of this real complex system,a fuzzy least squares support vector machine(FLS-SVM) soft measurement model was established and its parameters were optimized by using adaptive mutative scale chaos immune algorithm.The simulation results reveal that fuzzy least squares support vector machines soft measurement model is of better approximation accuracy and robustness.And application results show that the relative errors of the soft measurement model are less than 3.34%. 展开更多
关键词 CHAOS immune algorithm FUZZY support vector machine
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Immune Algorithm for Selecting Optimum Services in Web Services Composition 被引量:4
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作者 GAO Yan NA Jun ZHANG Bin YANG Lei GONG Qiang DAI Yu 《Wuhan University Journal of Natural Sciences》 EI CAS 2006年第1期221-225,共5页
For the problem of dynamic optimization in Web services composition, this paper presents a novel approach for selecting optimum Web services, which is based on the longest path method of weighted multistage graph. We ... For the problem of dynamic optimization in Web services composition, this paper presents a novel approach for selecting optimum Web services, which is based on the longest path method of weighted multistage graph. We propose and implement an Immune Algorithm for global optimization to construct composed Web services. Results of the experimentation illustrates that the algorithm in this paper has a powerful capability and can greatly improve the efficiency and veracity in service selection. 展开更多
关键词 Web services composition optimum selection immune algorithm
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Application of Particle Swarm Algorithm in the Optimal Allocation of Regional Water Resources Based on Immune Evolutionary Algorithm 被引量:5
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作者 屈国栋 楼章华 《Journal of Shanghai Jiaotong university(Science)》 EI 2013年第5期634-640,共7页
The optimal allocation model of regional water resources is built with the purpose of maximizing the comprehensive economic,social and environmental benefits of regional water consumption.In order to solve the problem... The optimal allocation model of regional water resources is built with the purpose of maximizing the comprehensive economic,social and environmental benefits of regional water consumption.In order to solve the problems that easily appear during the model solution of regional water resource optimal allocation with multiple water sources,multiple users and multiple objectives like"curse of dimensionality"or sinking into local optimum,this paper proposes a particle swarm optimization(PSO)algorithm based on immune evolutionary algorithm(IEA).This algorithm introduces immunology principle into particle swarm algorithm.Its immune memorizing and self-adjusting mechanism is utilized to keep the particles in the fitness level at a certain concentration and guarantee the diversity of population.Also,the global search characteristics of IEA and the local search capacity of particle swarm algorithm have been fully utilized to overcome the dependence of PSO on initial swarm and the deficiency of vulnerability to local optimum.After applying this model to the allocation of water resources in Zhoukou,we obtain the scheme for optimization allocation of water resources in the planning level years,i.e.2015and 2025 under the guarantee rate of 50%.The calculation results indicate that the application of this algorithm to solve the issue of optimal allocation of regional water resources is reliable and reasonable.Thus it ofers a new idea for solving the issue of optimal allocation of water resources. 展开更多
关键词 immune evolutionary algorithm(IEA) particle swarm optimization(PSO) water resources optimal allocation
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Feature selection for chemical process fault diagnosis by artificial immune systems 被引量:6
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作者 Liang Ming Jinsong Zhao 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2018年第8期1599-1604,共6页
With the Industry 4.0 era coming, modern chemical plants will be gradually transformed into smart factories, which sets higher requirements for fault detection and diagnosis(FDD) to enhance operation safety intelligen... With the Industry 4.0 era coming, modern chemical plants will be gradually transformed into smart factories, which sets higher requirements for fault detection and diagnosis(FDD) to enhance operation safety intelligence. In a typical chemical process, there are hundreds of process variables. Feature selection is a key to the efficiency and effectiveness of FDD. Even though artificial immune system has advantages in adaptation and independency on a large number of fault samples, antibody library construction used to be based on experience. It is not only time consuming, but also lack of scientific foundation in fault feature selection, which may deteriorate the FDD performance of the AIS. In this paper, a fault antibody feature selection optimization(FAFSO) algorithm is proposed based on genetic algorithm to optimize the fault antibody features and the antibody libraries' thresholds simultaneously. The performance of the proposed FAFSO algorithms is illustrated through the Tennessee Eastman benchmark problem. 展开更多
关键词 Artificial immune system Genetic algorithm Feature selection
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Immune algorithm for discretization of decision systems in rough set theory 被引量:4
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作者 JIA Ping DAI Jian-hua CHEN Wei-dong PAN Yun-he ZHU Miao-liang 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2006年第4期602-606,共5页
Rough set theory plays an important role in knowledge discovery, but cannot deal with continuous attributes, thus discretization is a problem which we cannot neglect. And discretization of decision systems in rough se... Rough set theory plays an important role in knowledge discovery, but cannot deal with continuous attributes, thus discretization is a problem which we cannot neglect. And discretization of decision systems in rough set theory has some particular characteristics. Consistency must be satisfied and cuts for discretization is expected to be as small as possible. Consistent and minimal discretization problem is NP-complete. In this paper, an immune algorithm for the problem is proposed. The correctness and effectiveness were shown in experiments. The discretization method presented in this paper can also be used as a data pre- treating step for other symbolic knowledge discovery or machine learning methods other than rough set theory. 展开更多
关键词 Rough sets DISCRETIZATION immune algorithm Decision system
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A bi-population immune algorithm for weapon transportation support scheduling problem with pickup and delivery on aircraft carrier deck 被引量:8
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作者 Fang Guo Wei Han +2 位作者 Xi-chao Su Yu-jie Liu Rong-wei Cui 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第4期119-134,共16页
The weapon transportation support scheduling problem on aircraft carrier deck is the key to restricting the sortie rate and combat capability of carrier-based aircraft.This paper studies the problem and presents a nov... The weapon transportation support scheduling problem on aircraft carrier deck is the key to restricting the sortie rate and combat capability of carrier-based aircraft.This paper studies the problem and presents a novel solution architecture.Taking the interference of the carrier-based aircraft deck layout on the weapon transportation route and precedence constraint into consideration,a mixed integer formulation is established to minimize the total objective,which is constituted of makespan,load variance and accumulative transfer time of support unit.Solution approach is developed for the model.Firstly,based on modeling the carrier aircraft parked on deck as convex obstacles,the path library of weapon transportation is constructed through visibility graph and Warshall-Floyd methods.We then propose a bi-population immune algorithm in which a population-based forward/backward scheduling technique,local search schemes and a chaotic catastrophe operator are embedded.Besides,the randomkey solution representation and serial scheduling generation scheme are adopted to conveniently obtain a better solution.The Taguchi method is additionally employed to determine key parameters of the algorithm.Finally,on a set of generated realistic instances,we demonstrate that the proposed algorithm outperforms all compared algorithms designed for similar optimization problems and can significantly improve the efficiency,and that the established model and the bi-population immune algorithm can effectively respond to the weapon support requirements of carrier-based aircraft under different sortie missions. 展开更多
关键词 Carrier-based aircraft Weapon transportation support scheduling Pickup and delivery Bi-population immune algorithm
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Immune Genetic Algorithm for Optimal Design 被引量:2
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作者 杨建国 李蓓智 项前 《Journal of Donghua University(English Edition)》 EI CAS 2002年第4期16-19,共4页
A computing model employing the immune and genetic algorithm (IGA) for the optimization of part design is presented. This model operates on a population of points in search space simultaneously, not on just one point.... A computing model employing the immune and genetic algorithm (IGA) for the optimization of part design is presented. This model operates on a population of points in search space simultaneously, not on just one point. It uses the objective function itself, not derivative or any other additional information and guarantees the fast convergence toward the global optimum. This method avoids some weak points in genetic algorithm, such as inefficient to some local searching problems and its convergence is too early. Based on this model, an optimal design support system (IGBODS) is developed.IGBODS has been used in practice and the result shows that this model has great advantage than traditional one and promises good application in optimal design. 展开更多
关键词 automation artificial immune system (AIS) Optimal design EVOLUTIONARY algorithm GENETIC algorithm
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Application of Immune Algorithm to Evaluation of Soil Resource Quality 被引量:3
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作者 YANG Hai-Dong HU Yue-Ming +2 位作者 DENG Fei-Qi CHEN Fei-Xiang WANG Fei 《Pedosphere》 SCIE CAS CSCD 2005年第5期660-668,共9页
Based on the geographic information system (GIS) technology, ArcInfo software was adopted to collect, process andanalyze spatial data of Guangdong Province for an evaluation of soil resource quality. The overlay analy... Based on the geographic information system (GIS) technology, ArcInfo software was adopted to collect, process andanalyze spatial data of Guangdong Province for an evaluation of soil resource quality. The overlay analysis method wasused in combining evaluation factors of Guangdong soil resource quality to determine the evaluation units. Because ofits favorable convergent speed and its ability to search solutions, the immune algorithm was applied to the soil resourcequality evaluation model. At the same time, the evaluation results of this newly proposed method were compared to twoother methods: sum of index and fuzzy synthetic. The results indicated that the immune algorithm reflected the actualcondition of soil resource quality more exactly. 展开更多
关键词 EVALUATION GIS immune algorithm soil resources
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