Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bac...Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bacterial structures,facilitating precise measurement of morphological variations and population behaviors at single-cell resolution.This paper reviews advancements in bacterial image segmentation,emphasizing the shift from traditional thresholding and watershed methods to deep learning-driven approaches.Convolutional neural networks(CNNs),U-Net architectures,and three-dimensional(3D)frameworks excel at segmenting dense biofilms and resolving antibiotic-induced morphological changes.These methods combine automated feature extraction with physics-informed postprocessing.Despite progress,challenges persist in computational efficiency,cross-species generalizability,and integration with multimodal experimental workflows.Future progress will depend on improving model robustness across species and imaging modalities,integrating multimodal data for phenotype-function mapping,and developing standard pipelines that link computational tools with clinical diagnostics.These innovations will expand microbial phenotyping beyond structural analysis,enabling deeper insights into bacterial physiology and ecological interactions.展开更多
Satellite image segmentation plays a crucial role in remote sensing,supporting applications such as environmental monitoring,land use analysis,and disaster management.However,traditional segmentation methods often rel...Satellite image segmentation plays a crucial role in remote sensing,supporting applications such as environmental monitoring,land use analysis,and disaster management.However,traditional segmentation methods often rely on large amounts of labeled data,which are costly and time-consuming to obtain,especially in largescale or dynamic environments.To address this challenge,we propose the Semi-Supervised Multi-View Picture Fuzzy Clustering(SS-MPFC)algorithm,which improves segmentation accuracy and robustness,particularly in complex and uncertain remote sensing scenarios.SS-MPFC unifies three paradigms:semi-supervised learning,multi-view clustering,and picture fuzzy set theory.This integration allows the model to effectively utilize a small number of labeled samples,fuse complementary information from multiple data views,and handle the ambiguity and uncertainty inherent in satellite imagery.We design a novel objective function that jointly incorporates picture fuzzy membership functions across multiple views of the data,and embeds pairwise semi-supervised constraints(must-link and cannot-link)directly into the clustering process to enhance segmentation accuracy.Experiments conducted on several benchmark satellite datasets demonstrate that SS-MPFC significantly outperforms existing state-of-the-art methods in segmentation accuracy,noise robustness,and semantic interpretability.On the Augsburg dataset,SS-MPFC achieves a Purity of 0.8158 and an Accuracy of 0.6860,highlighting its outstanding robustness and efficiency.These results demonstrate that SSMPFC offers a scalable and effective solution for real-world satellite-based monitoring systems,particularly in scenarios where rapid annotation is infeasible,such as wildfire tracking,agricultural monitoring,and dynamic urban mapping.展开更多
Medical image segmentation is of critical importance in the domain of contemporary medical imaging.However,U-Net and its variants exhibit limitations in capturing complex nonlinear patterns and global contextual infor...Medical image segmentation is of critical importance in the domain of contemporary medical imaging.However,U-Net and its variants exhibit limitations in capturing complex nonlinear patterns and global contextual information.Although the subsequent U-KAN model enhances nonlinear representation capabilities,it still faces challenges such as gradient vanishing during deep network training and spatial detail loss during feature downsampling,resulting in insufficient segmentation accuracy for edge structures and minute lesions.To address these challenges,this paper proposes the RE-UKAN model,which innovatively improves upon U-KAN.Firstly,a residual network is introduced into the encoder to effectively mitigate gradient vanishing through cross-layer identity mappings,thus enhancing modelling capabilities for complex pathological structures.Secondly,Efficient Local Attention(ELA)is integrated to suppress spatial detail loss during downsampling,thereby improving the perception of edge structures and minute lesions.Experimental results on four public datasets demonstrate that RE-UKAN outperforms existing medical image segmentation methods across multiple evaluation metrics,with particularly outstanding performance on the TN-SCUI 2020 dataset,achieving IoU of 88.18%and Dice of 93.57%.Compared to the baseline model,it achieves improvements of 3.05%and 1.72%,respectively.These results fully demonstrate RE-UKAN’s superior detail retention capability and boundary recognition accuracy in complex medical image segmentation tasks,providing a reliable solution for clinical precision segmentation.展开更多
Image segmentation is attracting increasing attention in the field of medical image analysis.Since widespread utilization across various medical applications,ensuring and improving segmentation accuracy has become a c...Image segmentation is attracting increasing attention in the field of medical image analysis.Since widespread utilization across various medical applications,ensuring and improving segmentation accuracy has become a crucial topic of research.With advances in deep learning,researchers have developed numerous methods that combine Transformers and convolutional neural networks(CNNs)to create highly accurate models for medical image segmentation.However,efforts to further enhance accuracy by developing larger and more complex models or training with more extensive datasets,significantly increase computational resource consumption.To address this problem,we propose BiCLIP-nnFormer(the prefix"Bi"refers to the use of two distinct CLIP models),a virtual multimodal instrument that leverages CLIP models to enhance the segmentation performance of a medical segmentation model nnFormer.Since two CLIP models(PMC-CLIP and CoCa-CLIP)are pre-trained on large datasets,they do not require additional training,thus conserving computation resources.These models are used offline to extract image and text embeddings from medical images.These embeddings are then processed by the proposed 3D CLIP adapter,which adapts the CLIP knowledge for segmentation tasks by fine-tuning.Finally,the adapted embeddings are fused with feature maps extracted from the nnFormer encoder for generating predicted masks.This process enriches the representation capabilities of the feature maps by integrating global multimodal information,leading to more precise segmentation predictions.We demonstrate the superiority of BiCLIP-nnFormer and the effectiveness of using CLIP models to enhance nnFormer through experiments on two public datasets,namely the Synapse multi-organ segmentation dataset(Synapse)and the Automatic Cardiac Diagnosis Challenge dataset(ACDC),as well as a self-annotated lung multi-category segmentation dataset(LMCS).展开更多
Data augmentation plays an important role in training deep neural model by expanding the size and diversity of the dataset.Initially,data augmentation mainly involved some simple transformations of images.Later,in ord...Data augmentation plays an important role in training deep neural model by expanding the size and diversity of the dataset.Initially,data augmentation mainly involved some simple transformations of images.Later,in order to increase the diversity and complexity of data,more advanced methods appeared and evolved to sophisticated generative models.However,these methods required a mass of computation of training or searching.In this paper,a novel training-free method that utilises the Pre-Trained Segment Anything Model(SAM)model as a data augmentation tool(PTSAM-DA)is proposed to generate the augmented annotations for images.Without the need for training,it obtains prompt boxes from the original annotations and then feeds the boxes to the pre-trained SAM to generate diverse and improved annotations.In this way,annotations are augmented more ingenious than simple manipulations without incurring huge computation for training a data augmentation model.Multiple comparative experiments on three datasets are conducted,including an in-house dataset,ADE20K and COCO2017.On this in-house dataset,namely Agricultural Plot Segmentation Dataset,maximum improvements of 3.77%and 8.92%are gained in two mainstream metrics,mIoU and mAcc,respectively.Consequently,large vision models like SAM are proven to be promising not only in image segmentation but also in data augmentation.展开更多
Convolutional neural networks(CNNs)-based medical image segmentation technologies have been widely used in medical image segmentation because of their strong representation and generalization abilities.However,due to ...Convolutional neural networks(CNNs)-based medical image segmentation technologies have been widely used in medical image segmentation because of their strong representation and generalization abilities.However,due to the inability to effectively capture global information from images,CNNs can easily lead to loss of contours and textures in segmentation results.Notice that the transformer model can effectively capture the properties of long-range dependencies in the image,and furthermore,combining the CNN and the transformer can effectively extract local details and global contextual features of the image.Motivated by this,we propose a multi-branch and multi-scale attention network(M2ANet)for medical image segmentation,whose architecture consists of three components.Specifically,in the first component,we construct an adaptive multi-branch patch module for parallel extraction of image features to reduce information loss caused by downsampling.In the second component,we apply residual block to the well-known convolutional block attention module to enhance the network’s ability to recognize important features of images and alleviate the phenomenon of gradient vanishing.In the third component,we design a multi-scale feature fusion module,in which we adopt adaptive average pooling and position encoding to enhance contextual features,and then multi-head attention is introduced to further enrich feature representation.Finally,we validate the effectiveness and feasibility of the proposed M2ANet method through comparative experiments on four benchmark medical image segmentation datasets,particularly in the context of preserving contours and textures.展开更多
Convolutional neural network(CNN)with the encoder-decoder structure is popular in medical image segmentation due to its excellent local feature extraction ability but it faces limitations in capturing the global featu...Convolutional neural network(CNN)with the encoder-decoder structure is popular in medical image segmentation due to its excellent local feature extraction ability but it faces limitations in capturing the global feature.The transformer can extract the global information well but adapting it to small medical datasets is challenging and its computational complexity can be heavy.In this work,a serial and parallel network is proposed for the accurate 3D medical image segmentation by combining CNN and transformer and promoting feature interactions across various semantic levels.The core components of the proposed method include the cross window self-attention based transformer(CWST)and multi-scale local enhanced(MLE)modules.The CWST module enhances the global context understanding by partitioning 3D images into non-overlapping windows and calculating sparse global attention between windows.The MLE module selectively fuses features by computing the voxel attention between different branch features,and uses convolution to strengthen the dense local information.The experiments on the prostate,atrium,and pancreas MR/CT image datasets consistently demonstrate the advantage of the proposed method over six popular segmentation models in both qualitative evaluation and quantitative indexes such as dice similarity coefficient,Intersection over Union,95%Hausdorff distance and average symmetric surface distance.展开更多
Existing semi-supervisedmedical image segmentation algorithms use copy-paste data augmentation to correct the labeled-unlabeled data distribution mismatch.However,current copy-paste methods have three limitations:(1)t...Existing semi-supervisedmedical image segmentation algorithms use copy-paste data augmentation to correct the labeled-unlabeled data distribution mismatch.However,current copy-paste methods have three limitations:(1)training the model solely with copy-paste mixed pictures from labeled and unlabeled input loses a lot of labeled information;(2)low-quality pseudo-labels can cause confirmation bias in pseudo-supervised learning on unlabeled data;(3)the segmentation performance in low-contrast and local regions is less than optimal.We design a Stochastic Augmentation-Based Dual-Teaching Auxiliary Training Strategy(SADT),which enhances feature diversity and learns high-quality features to overcome these problems.To be more precise,SADT trains the Student Network by using pseudo-label-based training from Teacher Network 1 and supervised learning with labeled data,which prevents the loss of rare labeled data.We introduce a bi-directional copy-pastemask with progressive high-entropy filtering to reduce data distribution disparities and mitigate confirmation bias in pseudo-supervision.For the mixed images,Deep-Shallow Spatial Contrastive Learning(DSSCL)is proposed in the feature spaces of Teacher Network 2 and the Student Network to improve the segmentation capabilities in low-contrast and local areas.In this procedure,the features retrieved by the Student Network are subjected to a random feature perturbation technique.On two openly available datasets,extensive trials show that our proposed SADT performs much better than the state-ofthe-art semi-supervised medical segmentation techniques.Using only 10%of the labeled data for training,SADT was able to acquire a Dice score of 90.10%on the ACDC(Automatic Cardiac Diagnosis Challenge)dataset.展开更多
Traditional sheep identification is based on ear tags.However,the application of ear tags not only causes stress to the animals but also leads to loss of ear tags,which affects the correct recognition of sheep identit...Traditional sheep identification is based on ear tags.However,the application of ear tags not only causes stress to the animals but also leads to loss of ear tags,which affects the correct recognition of sheep identity.In contrast,the acquisition of sheep face images offers the advantages of being non-invasive and stress-free for the animals.Nevertheless,the extant convolutional neural network-based sheep face identification model is prone to the issue of inadequate refinement,which renders its implementation on farms challenging.To address this issue,this study presented a novel sheep face recognition model that employs advanced feature fusion techniques and precise image segmentation strategies.The images were preprocessed and accurately segmented using deep learning techniques,with a dataset constructed containing sheep face images from multiple viewpoints(left,front,and right faces).In particular,the model employs a segmentation algorithm to delineate the sheep face region accurately,utilizes the Improved Convolutional Block Attention Module(I-CBAM)to emphasize the salient features of the sheep face,and achieves multi-scale fusion of the features through a Feature Pyramid Network(FPN).This process guarantees that the features captured from disparate viewpoints can be efficiently integrated to enhance recognition accuracy.Furthermore,the model guarantees the precise delineation of sheep facial contours by streamlining the image segmentation procedure,thereby establishing a robust basis for the precise identification of sheep identity.The findings demonstrate that the recognition accuracy of the Sheep Face Mask Region-based Convolutional Neural Network(SFMask RCNN)model has been enhanced by 9.64%to 98.65%in comparison to the original model.The method offers a novel technological approach to the management of animal identity in the context of sheep husbandry.展开更多
Medical image segmentation has become a cornerstone for many healthcare applications,allowing for the automated extraction of critical information from images such as Computed Tomography(CT)scans,Magnetic Resonance Im...Medical image segmentation has become a cornerstone for many healthcare applications,allowing for the automated extraction of critical information from images such as Computed Tomography(CT)scans,Magnetic Resonance Imaging(MRIs),and X-rays.The introduction of U-Net in 2015 has significantly advanced segmentation capabilities,especially for small datasets commonly found in medical imaging.Since then,various modifications to the original U-Net architecture have been proposed to enhance segmentation accuracy and tackle challenges like class imbalance,data scarcity,and multi-modal image processing.This paper provides a detailed review and comparison of several U-Net-based architectures,focusing on their effectiveness in medical image segmentation tasks.We evaluate performance metrics such as Dice Similarity Coefficient(DSC)and Intersection over Union(IoU)across different U-Net variants including HmsU-Net,CrossU-Net,mResU-Net,and others.Our results indicate that architectural enhancements such as transformers,attention mechanisms,and residual connections improve segmentation performance across diverse medical imaging applications,including tumor detection,organ segmentation,and lesion identification.The study also identifies current challenges in the field,including data variability,limited dataset sizes,and issues with class imbalance.Based on these findings,the paper suggests potential future directions for improving the robustness and clinical applicability of U-Net-based models in medical image segmentation.展开更多
The self-attention mechanism of Transformers,which captures long-range contextual information,has demonstrated significant potential in image segmentation.However,their ability to learn local,contextual relationships ...The self-attention mechanism of Transformers,which captures long-range contextual information,has demonstrated significant potential in image segmentation.However,their ability to learn local,contextual relationships between pixels requires further improvement.Previous methods face challenges in efficiently managing multi-scale fea-tures of different granularities from the encoder backbone,leaving room for improvement in their global representation and feature extraction capabilities.To address these challenges,we propose a novel Decoder with Multi-Head Feature Receptors(DMHFR),which receives multi-scale features from the encoder backbone and organizes them into three feature groups with different granularities:coarse,fine-grained,and full set.These groups are subsequently processed by Multi-Head Feature Receptors(MHFRs)after feature capture and modeling operations.MHFRs include two Three-Head Feature Receptors(THFRs)and one Four-Head Feature Receptor(FHFR).Each group of features is passed through these MHFRs and then fed into axial transformers,which help the model capture long-range dependencies within the features.The three MHFRs produce three distinct feature outputs.The output from the FHFR serves as auxiliary auxiliary features in the prediction head,and the prediction output and their losses will eventually be aggregated.Experimental results show that the Transformer using DMHFR outperforms 15 state of the arts(SOTA)methods on five public datasets.Specifically,it achieved significant improvements in mean DICE scores over the classic Parallel Reverse Attention Network(PraNet)method,with gains of 4.1%,2.2%,1.4%,8.9%,and 16.3%on the CVC-ClinicDB,Kvasir-SEG,CVC-T,CVC-ColonDB,and ETIS-LaribPolypDB datasets,respectively.展开更多
Remote sensing image segmentation has a wide range of applications in land cover classification,urban building recognition,crop monitoring,and other fields.In recent years,with the booming development of deep learning...Remote sensing image segmentation has a wide range of applications in land cover classification,urban building recognition,crop monitoring,and other fields.In recent years,with the booming development of deep learning,remote sensing image segmentation models based on deep learning have gradually emerged and produced a large number of scientific research achievements.This article is based on deep learning and reviews the latest achievements in remote sensing image segmentation,exploring future development directions.Firstly,the basic concepts,characteristics,classification,tasks,and commonly used datasets of remote sensingimages are presented.Secondly,the segmentation models based on deep learning were classified and summarized,and the principles,characteristics,and applications of various models were presented.Then,the key technologies involved in deep learning remote sensing image segmentation were introduced.Finally,the future development direction and applicationprospects of remote sensing image segmentation were discussed.This article reviews the latest research achievements in remote sensing image segmentationfrom the perspective of deep learning,which can provide reference and inspiration for the research of remote sensing image segmentation.展开更多
Despite its remarkable performance on natural images,the segment anything model(SAM)lacks domain-specific information in medical imaging.and faces the challenge of losing local multi-scale information in the encoding ...Despite its remarkable performance on natural images,the segment anything model(SAM)lacks domain-specific information in medical imaging.and faces the challenge of losing local multi-scale information in the encoding phase.This paper presents a medical image segmentation model based on SAM with a local multi-scale feature encoder(LMSFE-SAM)to address the issues above.Firstly,based on the SAM,a local multi-scale feature encoder is introduced to improve the representation of features within local receptive field,thereby supplying the Vision Transformer(ViT)branch in SAM with enriched local multi-scale contextual information.At the same time,a multiaxial Hadamard product module(MHPM)is incorporated into the local multi-scale feature encoder in a lightweight manner to reduce the quadratic complexity and noise interference.Subsequently,a cross-branch balancing adapter is designed to balance the local and global information between the local multi-scale feature encoder and the ViT encoder in SAM.Finally,to obtain smaller input image size and to mitigate overlapping in patch embeddings,the size of the input image is reduced from 1024×1024 pixels to 256×256 pixels,and a multidimensional information adaptation component is developed,which includes feature adapters,position adapters,and channel-spatial adapters.This component effectively integrates the information from small-sized medical images into SAM,enhancing its suitability for clinical deployment.The proposed model demonstrates an average enhancement ranging from 0.0387 to 0.3191 across six objective evaluation metrics on BUSI,DDTI,and TN3K datasets compared to eight other representative image segmentation models.This significantly enhances the performance of the SAM on medical images,providing clinicians with a powerful tool in clinical diagnosis.展开更多
In the field of medical image processing,combining global and local relationship modeling constitutes an effective strategy for precise segmentation.Prior research has established the validity of Convolutional Neural ...In the field of medical image processing,combining global and local relationship modeling constitutes an effective strategy for precise segmentation.Prior research has established the validity of Convolutional Neural Networks(CNN)in modeling local relationships.Conversely,Transformers have demonstrated their capability to effectively capture global contextual information.However,when utilized to address CNNs’limitations in modeling global relationships,Transformers are hindered by substantial computational complexity.To address this issue,we introduce Mamba,a State-Space Model(SSM)that exhibits exceptional proficiency in modeling long-range dependencies in sequential data.Given Mamba’s demonstrated potential in 2D medical image segmentation in previous studies,we have designed a Dual-encoder Global-local Feature Extraction Network based on Mamba,termed DGFE-Mamba,to accurately capture and fuse long-range dependencies and local dependencies within multi-scale features.Compared to Transformer-based methods,the DGFE-Mamba model excels in comprehensive feature modeling and demonstrates significantly improved segmentation accuracy.To validate the effectiveness and practicality of DGFE-Mamba,we conducted tests on the Automatic Cardiac Diagnosis Challenge(ACDC)dataset,the Synapse multi-organ CT abdominal segmentation dataset,and the Colorectal Cancer Clinic(CVC-ClinicDB)dataset.The results showed that DGFE-Mamba achieved Dice coefficients of 92.20,83.67,and 94.13,respectively.These findings comprehensively validate the effectiveness and practicality of the proposed DGFE-Mamba architecture.展开更多
A growing number of skin laser treatments have rapidly evolved and increased their role in the field of dermatology,laser treatment is considered to be used for a variety of pigmentary dermatosis as well as aesthetic ...A growing number of skin laser treatments have rapidly evolved and increased their role in the field of dermatology,laser treatment is considered to be used for a variety of pigmentary dermatosis as well as aesthetic problems.The standardized assessment of laser treatment efficacy is crucial for the interpretation and comparison of studies related to laser treatment of skin disorders.In this study,we propose an evaluation method to quantitatively assess laser treatment efficacy based on the image segmentation technology.A tattoo model of Sprague Dawley(SD)rats was established and treated by picosecond laser treatments at varying energy levels.Images of the tattoo models were captured before and after laser treatment,and feature extraction was conducted to quantify the tattooed area and pigment gradation.Subsequently,the clearance rate,which has been a standardized parameter,was calculated.The results indicate that the clearance rates obtained through this quantitative algorithm are comparable and exhibit smaller standard deviations compared with scale scores(4.59%versus 7.93%in the low-energy group,4.01%versus 9.05%in the medium-energy group,and 4.29%versus 10.23%in the high-energy group).This underscores the greater accuracy,objectivity,and reproducibility in assessing treatment responses.The quantitative evaluation of pigment removal holds promise for facilitating faster and more robust assessments in research and development.Additionally,it may enable the optimization of treatments tailored to individual patients,thereby contributing to more effective and personalized dermatological care.展开更多
Deep learning(DL),derived from the domain of Artificial Neural Networks(ANN),forms one of the most essential components of modern deep learning algorithms.DL segmentation models rely on layer-by-layer convolution-base...Deep learning(DL),derived from the domain of Artificial Neural Networks(ANN),forms one of the most essential components of modern deep learning algorithms.DL segmentation models rely on layer-by-layer convolution-based feature representation,guided by forward and backward propagation.Acritical aspect of this process is the selection of an appropriate activation function(AF)to ensure robustmodel learning.However,existing activation functions often fail to effectively address the vanishing gradient problem or are complicated by the need for manual parameter tuning.Most current research on activation function design focuses on classification tasks using natural image datasets such asMNIST,CIFAR-10,and CIFAR-100.To address this gap,this study proposesMed-ReLU,a novel activation function specifically designed for medical image segmentation.Med-ReLU prevents deep learning models fromsuffering dead neurons or vanishing gradient issues.It is a hybrid activation function that combines the properties of ReLU and Softsign.For positive inputs,Med-ReLU adopts the linear behavior of ReLU to avoid vanishing gradients,while for negative inputs,it exhibits the Softsign’s polynomial convergence,ensuring robust training and avoiding inactive neurons across the training set.The training performance and segmentation accuracy ofMed-ReLU have been thoroughly evaluated,demonstrating stable learning behavior and resistance to overfitting.It consistently outperforms state-of-the-art activation functions inmedical image segmentation tasks.Designed as a parameter-free function,Med-ReLU is simple to implement in complex deep learning architectures,and its effectiveness spans various neural network models and anomaly detection scenarios.展开更多
Multi-threshold image segmentation techniques based on intelligent optimization algorithms show great potential in low-cost,real-time applications.These methods are efficient even with limited computational resources....Multi-threshold image segmentation techniques based on intelligent optimization algorithms show great potential in low-cost,real-time applications.These methods are efficient even with limited computational resources.This paper proposes a multi-strategy improved red-billed blue magpie optimizer(MIRBMO)for Kapur multi-threshold image segmentation,aiming to enhance segmentation quality.First,Sobol sequences with elite reverse learning are used to optimize the distribution of the initial population,accelerating the optimization process.Second,lens imaging reverse learning is introduced to help the algorithm escape local optima.Finally,the golden sine strategy is adopted to increase the search space diversity and explore potential optimal solutions.The algorithm’s performance is evaluated using the 8 classic benchmark test functions,and results show that MIRBMO outperforms red-billed blue magpie optimizer(RBMO)in optimization capability and demonstrates clear advantages over other intelligent optimization algorithms.When applied to Kapur multi-threshold segmentation,MIRBMO yields a threshold combination with higher entropy values and produces segmented images with superior peak signal-to-noise ratio(PSNR),structural similarity index measure(SSIM),and feature similarity index measure(FSIM)values,indicating its strong application potential.展开更多
In the realm of medical image segmentation,particularly in cardiac magnetic resonance imaging(MRI),achieving robust performance with limited annotated data is a significant challenge.Performance often degrades when fa...In the realm of medical image segmentation,particularly in cardiac magnetic resonance imaging(MRI),achieving robust performance with limited annotated data is a significant challenge.Performance often degrades when faced with testing scenarios from unknown domains.To address this problem,this paper proposes a novel semi-supervised approach for cardiac magnetic resonance image segmentation,aiming to enhance predictive capabilities and domain generalization(DG).This paper establishes an MT-like model utilizing pseudo-labeling and consistency regularization from semi-supervised learning,and integrates uncertainty estimation to improve the accuracy of pseudo-labels.Additionally,to tackle the challenge of domain generalization,a data manipulation strategy is introduced,extracting spatial and content-related information from images across different domains,enriching the dataset with a multi-domain perspective.This papers method is meticulously evaluated on the publicly available cardiac magnetic resonance imaging dataset M&Ms,validating its effectiveness.Comparative analyses against various methods highlight the out-standing performance of this papers approach,demonstrating its capability to segment cardiac magnetic resonance images in previously unseen domains even with limited annotated data.展开更多
Medical image segmentation,i.e.,labeling structures of interest in medical images,is crucial for disease diagnosis and treatment in radiology.In reversible data hiding in medical images(RDHMI),segmentation consists of...Medical image segmentation,i.e.,labeling structures of interest in medical images,is crucial for disease diagnosis and treatment in radiology.In reversible data hiding in medical images(RDHMI),segmentation consists of only two regions:the focal and nonfocal regions.The focal region mainly contains information for diagnosis,while the nonfocal region serves as the monochrome background.The current traditional segmentation methods utilized in RDHMI are inaccurate for complex medical images,and manual segmentation is time-consuming,poorly reproducible,and operator-dependent.Implementing state-of-the-art deep learning(DL)models will facilitate key benefits,but the lack of domain-specific labels for existing medical datasets makes it impossible.To address this problem,this study provides labels of existing medical datasets based on a hybrid segmentation approach to facilitate the implementation of DL segmentation models in this domain.First,an initial segmentation based on a 33 kernel is performed to analyze×identified contour pixels before classifying pixels into focal and nonfocal regions.Then,several human expert raters evaluate and classify the generated labels into accurate and inaccurate labels.The inaccurate labels undergo manual segmentation by medical practitioners and are scored based on a hierarchical voting scheme before being assigned to the proposed dataset.To ensure reliability and integrity in the proposed dataset,we evaluate the accurate automated labels with manually segmented labels by medical practitioners using five assessment metrics:dice coefficient,Jaccard index,precision,recall,and accuracy.The experimental results show labels in the proposed dataset are consistent with the subjective judgment of human experts,with an average accuracy score of 94%and dice coefficient scores between 90%-99%.The study further proposes a ResNet-UNet with concatenated spatial and channel squeeze and excitation(scSE)architecture for semantic segmentation to validate and illustrate the usefulness of the proposed dataset.The results demonstrate the superior performance of the proposed architecture in accurately separating the focal and nonfocal regions compared to state-of-the-art architectures.Dataset information is released under the following URL:https://www.kaggle.com/lordamoah/datasets(accessed on 31 March 2025).展开更多
Medical image segmentation is a crucial task in clinical applications.However,obtaining labeled data for medical images is often challenging.This has led to the appeal of semi-supervised learning(SSL),a technique adep...Medical image segmentation is a crucial task in clinical applications.However,obtaining labeled data for medical images is often challenging.This has led to the appeal of semi-supervised learning(SSL),a technique adept at leveraging a modest amount of labeled data.Nonetheless,most prevailing SSL segmentation methods for medical images either rely on the single consistency training method or directly fine-tune SSL methods designed for natural images.In this paper,we propose an innovative semi-supervised method called multi-consistency training(MCT)for medical image segmentation.Our approach transcends the constraints of prior methodologies by considering consistency from a dual perspective:output consistency across different up-sampling methods and output consistency of the same data within the same network under various perturbations to the intermediate features.We design distinct semi-supervised loss regression methods for these two types of consistencies.To enhance the application of our MCT model,we also develop a dedicated decoder as the core of our neural network.Thorough experiments were conducted on the polyp dataset and the dental dataset,rigorously compared against other SSL methods.Experimental results demonstrate the superiority of our approach,achieving higher segmentation accuracy.Moreover,comprehensive ablation studies and insightful discussion substantiate the efficacy of our approach in navigating the intricacies of medical image segmentation.展开更多
基金financially supported by the Open Project Program of Wuhan National Laboratory for Optoelectronics(No.2022WNLOKF009)the National Natural Science Foundation of China(No.62475216)+2 种基金the Key Research and Development Program of Shaanxi(No.2024GH-ZDXM-37)the Fujian Provincial Natural Science Foundation of China(No.2024J01060)the Startup Program of XMU,and the Fundamental Research Funds for the Central Universities.
文摘Microscopy imaging is fundamental in analyzing bacterial morphology and dynamics,offering critical insights into bacterial physiology and pathogenicity.Image segmentation techniques enable quantitative analysis of bacterial structures,facilitating precise measurement of morphological variations and population behaviors at single-cell resolution.This paper reviews advancements in bacterial image segmentation,emphasizing the shift from traditional thresholding and watershed methods to deep learning-driven approaches.Convolutional neural networks(CNNs),U-Net architectures,and three-dimensional(3D)frameworks excel at segmenting dense biofilms and resolving antibiotic-induced morphological changes.These methods combine automated feature extraction with physics-informed postprocessing.Despite progress,challenges persist in computational efficiency,cross-species generalizability,and integration with multimodal experimental workflows.Future progress will depend on improving model robustness across species and imaging modalities,integrating multimodal data for phenotype-function mapping,and developing standard pipelines that link computational tools with clinical diagnostics.These innovations will expand microbial phenotyping beyond structural analysis,enabling deeper insights into bacterial physiology and ecological interactions.
基金funded by the Research Project:THTETN.05/24-25,VietnamAcademy of Science and Technology.
文摘Satellite image segmentation plays a crucial role in remote sensing,supporting applications such as environmental monitoring,land use analysis,and disaster management.However,traditional segmentation methods often rely on large amounts of labeled data,which are costly and time-consuming to obtain,especially in largescale or dynamic environments.To address this challenge,we propose the Semi-Supervised Multi-View Picture Fuzzy Clustering(SS-MPFC)algorithm,which improves segmentation accuracy and robustness,particularly in complex and uncertain remote sensing scenarios.SS-MPFC unifies three paradigms:semi-supervised learning,multi-view clustering,and picture fuzzy set theory.This integration allows the model to effectively utilize a small number of labeled samples,fuse complementary information from multiple data views,and handle the ambiguity and uncertainty inherent in satellite imagery.We design a novel objective function that jointly incorporates picture fuzzy membership functions across multiple views of the data,and embeds pairwise semi-supervised constraints(must-link and cannot-link)directly into the clustering process to enhance segmentation accuracy.Experiments conducted on several benchmark satellite datasets demonstrate that SS-MPFC significantly outperforms existing state-of-the-art methods in segmentation accuracy,noise robustness,and semantic interpretability.On the Augsburg dataset,SS-MPFC achieves a Purity of 0.8158 and an Accuracy of 0.6860,highlighting its outstanding robustness and efficiency.These results demonstrate that SSMPFC offers a scalable and effective solution for real-world satellite-based monitoring systems,particularly in scenarios where rapid annotation is infeasible,such as wildfire tracking,agricultural monitoring,and dynamic urban mapping.
文摘Medical image segmentation is of critical importance in the domain of contemporary medical imaging.However,U-Net and its variants exhibit limitations in capturing complex nonlinear patterns and global contextual information.Although the subsequent U-KAN model enhances nonlinear representation capabilities,it still faces challenges such as gradient vanishing during deep network training and spatial detail loss during feature downsampling,resulting in insufficient segmentation accuracy for edge structures and minute lesions.To address these challenges,this paper proposes the RE-UKAN model,which innovatively improves upon U-KAN.Firstly,a residual network is introduced into the encoder to effectively mitigate gradient vanishing through cross-layer identity mappings,thus enhancing modelling capabilities for complex pathological structures.Secondly,Efficient Local Attention(ELA)is integrated to suppress spatial detail loss during downsampling,thereby improving the perception of edge structures and minute lesions.Experimental results on four public datasets demonstrate that RE-UKAN outperforms existing medical image segmentation methods across multiple evaluation metrics,with particularly outstanding performance on the TN-SCUI 2020 dataset,achieving IoU of 88.18%and Dice of 93.57%.Compared to the baseline model,it achieves improvements of 3.05%and 1.72%,respectively.These results fully demonstrate RE-UKAN’s superior detail retention capability and boundary recognition accuracy in complex medical image segmentation tasks,providing a reliable solution for clinical precision segmentation.
基金funded by the National Natural Science Foundation of China(Grant No.6240072655)the Hubei Provincial Key Research and Development Program(Grant No.2023BCB151)+1 种基金the Wuhan Natural Science Foundation Exploration Program(Chenguang Program,Grant No.2024040801020202)the Natural Science Foundation of Hubei Province of China(Grant No.2025AFB148).
文摘Image segmentation is attracting increasing attention in the field of medical image analysis.Since widespread utilization across various medical applications,ensuring and improving segmentation accuracy has become a crucial topic of research.With advances in deep learning,researchers have developed numerous methods that combine Transformers and convolutional neural networks(CNNs)to create highly accurate models for medical image segmentation.However,efforts to further enhance accuracy by developing larger and more complex models or training with more extensive datasets,significantly increase computational resource consumption.To address this problem,we propose BiCLIP-nnFormer(the prefix"Bi"refers to the use of two distinct CLIP models),a virtual multimodal instrument that leverages CLIP models to enhance the segmentation performance of a medical segmentation model nnFormer.Since two CLIP models(PMC-CLIP and CoCa-CLIP)are pre-trained on large datasets,they do not require additional training,thus conserving computation resources.These models are used offline to extract image and text embeddings from medical images.These embeddings are then processed by the proposed 3D CLIP adapter,which adapts the CLIP knowledge for segmentation tasks by fine-tuning.Finally,the adapted embeddings are fused with feature maps extracted from the nnFormer encoder for generating predicted masks.This process enriches the representation capabilities of the feature maps by integrating global multimodal information,leading to more precise segmentation predictions.We demonstrate the superiority of BiCLIP-nnFormer and the effectiveness of using CLIP models to enhance nnFormer through experiments on two public datasets,namely the Synapse multi-organ segmentation dataset(Synapse)and the Automatic Cardiac Diagnosis Challenge dataset(ACDC),as well as a self-annotated lung multi-category segmentation dataset(LMCS).
基金Natural Science Foundation of Zhejiang Province,Grant/Award Number:LY23F020025Science and Technology Commissioner Program of Huzhou,Grant/Award Number:2023GZ42Sichuan Provincial Science and Technology Support Program,Grant/Award Numbers:2023ZHCG0005,2023ZHCG0008。
文摘Data augmentation plays an important role in training deep neural model by expanding the size and diversity of the dataset.Initially,data augmentation mainly involved some simple transformations of images.Later,in order to increase the diversity and complexity of data,more advanced methods appeared and evolved to sophisticated generative models.However,these methods required a mass of computation of training or searching.In this paper,a novel training-free method that utilises the Pre-Trained Segment Anything Model(SAM)model as a data augmentation tool(PTSAM-DA)is proposed to generate the augmented annotations for images.Without the need for training,it obtains prompt boxes from the original annotations and then feeds the boxes to the pre-trained SAM to generate diverse and improved annotations.In this way,annotations are augmented more ingenious than simple manipulations without incurring huge computation for training a data augmentation model.Multiple comparative experiments on three datasets are conducted,including an in-house dataset,ADE20K and COCO2017.On this in-house dataset,namely Agricultural Plot Segmentation Dataset,maximum improvements of 3.77%and 8.92%are gained in two mainstream metrics,mIoU and mAcc,respectively.Consequently,large vision models like SAM are proven to be promising not only in image segmentation but also in data augmentation.
基金supported by the Natural Science Foundation of the Anhui Higher Education Institutions of China(Grant Nos.2023AH040149 and 2024AH051915)the Anhui Provincial Natural Science Foundation(Grant No.2208085MF168)+1 种基金the Science and Technology Innovation Tackle Plan Project of Maanshan(Grant No.2024RGZN001)the Scientific Research Fund Project of Anhui Medical University(Grant No.2023xkj122).
文摘Convolutional neural networks(CNNs)-based medical image segmentation technologies have been widely used in medical image segmentation because of their strong representation and generalization abilities.However,due to the inability to effectively capture global information from images,CNNs can easily lead to loss of contours and textures in segmentation results.Notice that the transformer model can effectively capture the properties of long-range dependencies in the image,and furthermore,combining the CNN and the transformer can effectively extract local details and global contextual features of the image.Motivated by this,we propose a multi-branch and multi-scale attention network(M2ANet)for medical image segmentation,whose architecture consists of three components.Specifically,in the first component,we construct an adaptive multi-branch patch module for parallel extraction of image features to reduce information loss caused by downsampling.In the second component,we apply residual block to the well-known convolutional block attention module to enhance the network’s ability to recognize important features of images and alleviate the phenomenon of gradient vanishing.In the third component,we design a multi-scale feature fusion module,in which we adopt adaptive average pooling and position encoding to enhance contextual features,and then multi-head attention is introduced to further enrich feature representation.Finally,we validate the effectiveness and feasibility of the proposed M2ANet method through comparative experiments on four benchmark medical image segmentation datasets,particularly in the context of preserving contours and textures.
基金National Key Research and Development Program of China,Grant/Award Number:2018YFE0206900China Postdoctoral Science Foundation,Grant/Award Number:2023M731204+2 种基金The Open Project of Key Laboratory for Quality Evaluation of Ultrasound Surgical Equipment of National Medical Products Administration,Grant/Award Number:SMDTKL-2023-1-01The Hubei Province Key Research and Development Project,Grant/Award Number:2023BCB007CAAI-Huawei MindSpore Open Fund。
文摘Convolutional neural network(CNN)with the encoder-decoder structure is popular in medical image segmentation due to its excellent local feature extraction ability but it faces limitations in capturing the global feature.The transformer can extract the global information well but adapting it to small medical datasets is challenging and its computational complexity can be heavy.In this work,a serial and parallel network is proposed for the accurate 3D medical image segmentation by combining CNN and transformer and promoting feature interactions across various semantic levels.The core components of the proposed method include the cross window self-attention based transformer(CWST)and multi-scale local enhanced(MLE)modules.The CWST module enhances the global context understanding by partitioning 3D images into non-overlapping windows and calculating sparse global attention between windows.The MLE module selectively fuses features by computing the voxel attention between different branch features,and uses convolution to strengthen the dense local information.The experiments on the prostate,atrium,and pancreas MR/CT image datasets consistently demonstrate the advantage of the proposed method over six popular segmentation models in both qualitative evaluation and quantitative indexes such as dice similarity coefficient,Intersection over Union,95%Hausdorff distance and average symmetric surface distance.
基金supported by the Natural Science Foundation of China(No.41804112,author:Chengyun Song).
文摘Existing semi-supervisedmedical image segmentation algorithms use copy-paste data augmentation to correct the labeled-unlabeled data distribution mismatch.However,current copy-paste methods have three limitations:(1)training the model solely with copy-paste mixed pictures from labeled and unlabeled input loses a lot of labeled information;(2)low-quality pseudo-labels can cause confirmation bias in pseudo-supervised learning on unlabeled data;(3)the segmentation performance in low-contrast and local regions is less than optimal.We design a Stochastic Augmentation-Based Dual-Teaching Auxiliary Training Strategy(SADT),which enhances feature diversity and learns high-quality features to overcome these problems.To be more precise,SADT trains the Student Network by using pseudo-label-based training from Teacher Network 1 and supervised learning with labeled data,which prevents the loss of rare labeled data.We introduce a bi-directional copy-pastemask with progressive high-entropy filtering to reduce data distribution disparities and mitigate confirmation bias in pseudo-supervision.For the mixed images,Deep-Shallow Spatial Contrastive Learning(DSSCL)is proposed in the feature spaces of Teacher Network 2 and the Student Network to improve the segmentation capabilities in low-contrast and local areas.In this procedure,the features retrieved by the Student Network are subjected to a random feature perturbation technique.On two openly available datasets,extensive trials show that our proposed SADT performs much better than the state-ofthe-art semi-supervised medical segmentation techniques.Using only 10%of the labeled data for training,SADT was able to acquire a Dice score of 90.10%on the ACDC(Automatic Cardiac Diagnosis Challenge)dataset.
基金Fundamental Research Funds for Inner Mongolia Directly Affiliated Universities(Grant No.BR221032)the First Class Disciplines Research Special Project(Grant No.YLXKZX-NND-009)。
文摘Traditional sheep identification is based on ear tags.However,the application of ear tags not only causes stress to the animals but also leads to loss of ear tags,which affects the correct recognition of sheep identity.In contrast,the acquisition of sheep face images offers the advantages of being non-invasive and stress-free for the animals.Nevertheless,the extant convolutional neural network-based sheep face identification model is prone to the issue of inadequate refinement,which renders its implementation on farms challenging.To address this issue,this study presented a novel sheep face recognition model that employs advanced feature fusion techniques and precise image segmentation strategies.The images were preprocessed and accurately segmented using deep learning techniques,with a dataset constructed containing sheep face images from multiple viewpoints(left,front,and right faces).In particular,the model employs a segmentation algorithm to delineate the sheep face region accurately,utilizes the Improved Convolutional Block Attention Module(I-CBAM)to emphasize the salient features of the sheep face,and achieves multi-scale fusion of the features through a Feature Pyramid Network(FPN).This process guarantees that the features captured from disparate viewpoints can be efficiently integrated to enhance recognition accuracy.Furthermore,the model guarantees the precise delineation of sheep facial contours by streamlining the image segmentation procedure,thereby establishing a robust basis for the precise identification of sheep identity.The findings demonstrate that the recognition accuracy of the Sheep Face Mask Region-based Convolutional Neural Network(SFMask RCNN)model has been enhanced by 9.64%to 98.65%in comparison to the original model.The method offers a novel technological approach to the management of animal identity in the context of sheep husbandry.
文摘Medical image segmentation has become a cornerstone for many healthcare applications,allowing for the automated extraction of critical information from images such as Computed Tomography(CT)scans,Magnetic Resonance Imaging(MRIs),and X-rays.The introduction of U-Net in 2015 has significantly advanced segmentation capabilities,especially for small datasets commonly found in medical imaging.Since then,various modifications to the original U-Net architecture have been proposed to enhance segmentation accuracy and tackle challenges like class imbalance,data scarcity,and multi-modal image processing.This paper provides a detailed review and comparison of several U-Net-based architectures,focusing on their effectiveness in medical image segmentation tasks.We evaluate performance metrics such as Dice Similarity Coefficient(DSC)and Intersection over Union(IoU)across different U-Net variants including HmsU-Net,CrossU-Net,mResU-Net,and others.Our results indicate that architectural enhancements such as transformers,attention mechanisms,and residual connections improve segmentation performance across diverse medical imaging applications,including tumor detection,organ segmentation,and lesion identification.The study also identifies current challenges in the field,including data variability,limited dataset sizes,and issues with class imbalance.Based on these findings,the paper suggests potential future directions for improving the robustness and clinical applicability of U-Net-based models in medical image segmentation.
基金supported by Xiamen Medical and Health Guidance Project in 2021(No.3502Z20214ZD1070)supported by a grant from Guangxi Key Laboratory of Machine Vision and Intelligent Control,China(No.2023B02).
文摘The self-attention mechanism of Transformers,which captures long-range contextual information,has demonstrated significant potential in image segmentation.However,their ability to learn local,contextual relationships between pixels requires further improvement.Previous methods face challenges in efficiently managing multi-scale fea-tures of different granularities from the encoder backbone,leaving room for improvement in their global representation and feature extraction capabilities.To address these challenges,we propose a novel Decoder with Multi-Head Feature Receptors(DMHFR),which receives multi-scale features from the encoder backbone and organizes them into three feature groups with different granularities:coarse,fine-grained,and full set.These groups are subsequently processed by Multi-Head Feature Receptors(MHFRs)after feature capture and modeling operations.MHFRs include two Three-Head Feature Receptors(THFRs)and one Four-Head Feature Receptor(FHFR).Each group of features is passed through these MHFRs and then fed into axial transformers,which help the model capture long-range dependencies within the features.The three MHFRs produce three distinct feature outputs.The output from the FHFR serves as auxiliary auxiliary features in the prediction head,and the prediction output and their losses will eventually be aggregated.Experimental results show that the Transformer using DMHFR outperforms 15 state of the arts(SOTA)methods on five public datasets.Specifically,it achieved significant improvements in mean DICE scores over the classic Parallel Reverse Attention Network(PraNet)method,with gains of 4.1%,2.2%,1.4%,8.9%,and 16.3%on the CVC-ClinicDB,Kvasir-SEG,CVC-T,CVC-ColonDB,and ETIS-LaribPolypDB datasets,respectively.
文摘Remote sensing image segmentation has a wide range of applications in land cover classification,urban building recognition,crop monitoring,and other fields.In recent years,with the booming development of deep learning,remote sensing image segmentation models based on deep learning have gradually emerged and produced a large number of scientific research achievements.This article is based on deep learning and reviews the latest achievements in remote sensing image segmentation,exploring future development directions.Firstly,the basic concepts,characteristics,classification,tasks,and commonly used datasets of remote sensingimages are presented.Secondly,the segmentation models based on deep learning were classified and summarized,and the principles,characteristics,and applications of various models were presented.Then,the key technologies involved in deep learning remote sensing image segmentation were introduced.Finally,the future development direction and applicationprospects of remote sensing image segmentation were discussed.This article reviews the latest research achievements in remote sensing image segmentationfrom the perspective of deep learning,which can provide reference and inspiration for the research of remote sensing image segmentation.
基金supported by Natural Science Foundation Programme of Gansu Province(No.24JRRA231)National Natural Science Foundation of China(No.62061023)Gansu Provincial Science and Technology Plan Key Research and Development Program Project(No.24YFFA024).
文摘Despite its remarkable performance on natural images,the segment anything model(SAM)lacks domain-specific information in medical imaging.and faces the challenge of losing local multi-scale information in the encoding phase.This paper presents a medical image segmentation model based on SAM with a local multi-scale feature encoder(LMSFE-SAM)to address the issues above.Firstly,based on the SAM,a local multi-scale feature encoder is introduced to improve the representation of features within local receptive field,thereby supplying the Vision Transformer(ViT)branch in SAM with enriched local multi-scale contextual information.At the same time,a multiaxial Hadamard product module(MHPM)is incorporated into the local multi-scale feature encoder in a lightweight manner to reduce the quadratic complexity and noise interference.Subsequently,a cross-branch balancing adapter is designed to balance the local and global information between the local multi-scale feature encoder and the ViT encoder in SAM.Finally,to obtain smaller input image size and to mitigate overlapping in patch embeddings,the size of the input image is reduced from 1024×1024 pixels to 256×256 pixels,and a multidimensional information adaptation component is developed,which includes feature adapters,position adapters,and channel-spatial adapters.This component effectively integrates the information from small-sized medical images into SAM,enhancing its suitability for clinical deployment.The proposed model demonstrates an average enhancement ranging from 0.0387 to 0.3191 across six objective evaluation metrics on BUSI,DDTI,and TN3K datasets compared to eight other representative image segmentation models.This significantly enhances the performance of the SAM on medical images,providing clinicians with a powerful tool in clinical diagnosis.
基金supported by the National Natural Science Foundation of China(62276092,62303167)the Postdoctoral Fellowship Program(Grade C)of China Postdoctoral Science Foundation(GZC20230707)+3 种基金the Key Science and Technology Program of Henan Province,China(242102211051)MRC(MC_PC_17171)Royal Society(RP202G0230)BHF(AA/18/3/34220)。
文摘In the field of medical image processing,combining global and local relationship modeling constitutes an effective strategy for precise segmentation.Prior research has established the validity of Convolutional Neural Networks(CNN)in modeling local relationships.Conversely,Transformers have demonstrated their capability to effectively capture global contextual information.However,when utilized to address CNNs’limitations in modeling global relationships,Transformers are hindered by substantial computational complexity.To address this issue,we introduce Mamba,a State-Space Model(SSM)that exhibits exceptional proficiency in modeling long-range dependencies in sequential data.Given Mamba’s demonstrated potential in 2D medical image segmentation in previous studies,we have designed a Dual-encoder Global-local Feature Extraction Network based on Mamba,termed DGFE-Mamba,to accurately capture and fuse long-range dependencies and local dependencies within multi-scale features.Compared to Transformer-based methods,the DGFE-Mamba model excels in comprehensive feature modeling and demonstrates significantly improved segmentation accuracy.To validate the effectiveness and practicality of DGFE-Mamba,we conducted tests on the Automatic Cardiac Diagnosis Challenge(ACDC)dataset,the Synapse multi-organ CT abdominal segmentation dataset,and the Colorectal Cancer Clinic(CVC-ClinicDB)dataset.The results showed that DGFE-Mamba achieved Dice coefficients of 92.20,83.67,and 94.13,respectively.These findings comprehensively validate the effectiveness and practicality of the proposed DGFE-Mamba architecture.
基金supported by The Shanghai Science and Technology Commission(21S31902700)。
文摘A growing number of skin laser treatments have rapidly evolved and increased their role in the field of dermatology,laser treatment is considered to be used for a variety of pigmentary dermatosis as well as aesthetic problems.The standardized assessment of laser treatment efficacy is crucial for the interpretation and comparison of studies related to laser treatment of skin disorders.In this study,we propose an evaluation method to quantitatively assess laser treatment efficacy based on the image segmentation technology.A tattoo model of Sprague Dawley(SD)rats was established and treated by picosecond laser treatments at varying energy levels.Images of the tattoo models were captured before and after laser treatment,and feature extraction was conducted to quantify the tattooed area and pigment gradation.Subsequently,the clearance rate,which has been a standardized parameter,was calculated.The results indicate that the clearance rates obtained through this quantitative algorithm are comparable and exhibit smaller standard deviations compared with scale scores(4.59%versus 7.93%in the low-energy group,4.01%versus 9.05%in the medium-energy group,and 4.29%versus 10.23%in the high-energy group).This underscores the greater accuracy,objectivity,and reproducibility in assessing treatment responses.The quantitative evaluation of pigment removal holds promise for facilitating faster and more robust assessments in research and development.Additionally,it may enable the optimization of treatments tailored to individual patients,thereby contributing to more effective and personalized dermatological care.
基金The researchers would like to thank the Deanship of Graduate Studies and Scientific Research at Qassim University for financial support(QU-APC-2025).
文摘Deep learning(DL),derived from the domain of Artificial Neural Networks(ANN),forms one of the most essential components of modern deep learning algorithms.DL segmentation models rely on layer-by-layer convolution-based feature representation,guided by forward and backward propagation.Acritical aspect of this process is the selection of an appropriate activation function(AF)to ensure robustmodel learning.However,existing activation functions often fail to effectively address the vanishing gradient problem or are complicated by the need for manual parameter tuning.Most current research on activation function design focuses on classification tasks using natural image datasets such asMNIST,CIFAR-10,and CIFAR-100.To address this gap,this study proposesMed-ReLU,a novel activation function specifically designed for medical image segmentation.Med-ReLU prevents deep learning models fromsuffering dead neurons or vanishing gradient issues.It is a hybrid activation function that combines the properties of ReLU and Softsign.For positive inputs,Med-ReLU adopts the linear behavior of ReLU to avoid vanishing gradients,while for negative inputs,it exhibits the Softsign’s polynomial convergence,ensuring robust training and avoiding inactive neurons across the training set.The training performance and segmentation accuracy ofMed-ReLU have been thoroughly evaluated,demonstrating stable learning behavior and resistance to overfitting.It consistently outperforms state-of-the-art activation functions inmedical image segmentation tasks.Designed as a parameter-free function,Med-ReLU is simple to implement in complex deep learning architectures,and its effectiveness spans various neural network models and anomaly detection scenarios.
基金Supported by the National Key R&D Program of China:Science and Technology Innovation 2030-‘New Generation Artificial Intelligence’Major Project(2022ZD0119000)the Natural Science Foundation of Shaanxi Province(2025JC-YBMS-736,2025JC-YBMS-343)the Shaanxi Province Key Research and Development Project(2025CY-YBXM-061).
文摘Multi-threshold image segmentation techniques based on intelligent optimization algorithms show great potential in low-cost,real-time applications.These methods are efficient even with limited computational resources.This paper proposes a multi-strategy improved red-billed blue magpie optimizer(MIRBMO)for Kapur multi-threshold image segmentation,aiming to enhance segmentation quality.First,Sobol sequences with elite reverse learning are used to optimize the distribution of the initial population,accelerating the optimization process.Second,lens imaging reverse learning is introduced to help the algorithm escape local optima.Finally,the golden sine strategy is adopted to increase the search space diversity and explore potential optimal solutions.The algorithm’s performance is evaluated using the 8 classic benchmark test functions,and results show that MIRBMO outperforms red-billed blue magpie optimizer(RBMO)in optimization capability and demonstrates clear advantages over other intelligent optimization algorithms.When applied to Kapur multi-threshold segmentation,MIRBMO yields a threshold combination with higher entropy values and produces segmented images with superior peak signal-to-noise ratio(PSNR),structural similarity index measure(SSIM),and feature similarity index measure(FSIM)values,indicating its strong application potential.
基金Supported by the National Natural Science Foundation of China(No.62001313)the Key Project of Liaoning Provincial Department of Science and Technology(No.2021JH2/10300134,2022JH1/10500004)。
文摘In the realm of medical image segmentation,particularly in cardiac magnetic resonance imaging(MRI),achieving robust performance with limited annotated data is a significant challenge.Performance often degrades when faced with testing scenarios from unknown domains.To address this problem,this paper proposes a novel semi-supervised approach for cardiac magnetic resonance image segmentation,aiming to enhance predictive capabilities and domain generalization(DG).This paper establishes an MT-like model utilizing pseudo-labeling and consistency regularization from semi-supervised learning,and integrates uncertainty estimation to improve the accuracy of pseudo-labels.Additionally,to tackle the challenge of domain generalization,a data manipulation strategy is introduced,extracting spatial and content-related information from images across different domains,enriching the dataset with a multi-domain perspective.This papers method is meticulously evaluated on the publicly available cardiac magnetic resonance imaging dataset M&Ms,validating its effectiveness.Comparative analyses against various methods highlight the out-standing performance of this papers approach,demonstrating its capability to segment cardiac magnetic resonance images in previously unseen domains even with limited annotated data.
基金supported by the National Natural Science Foundation of China(Grant Nos.62072250,61772281,61702235,U1636117,U1804263,62172435,61872203 and 61802212)the Zhongyuan Science and Technology Innovation Leading Talent Project of China(Grant No.214200510019)+3 种基金the Suqian Municipal Science and Technology Plan Project in 2020(S202015)the Plan for Scientific Talent of Henan Province(Grant No.2018JR0018)the Opening Project of Guangdong Provincial Key Laboratory of Information Security Technology(Grant No.2020B1212060078)the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)Fund.
文摘Medical image segmentation,i.e.,labeling structures of interest in medical images,is crucial for disease diagnosis and treatment in radiology.In reversible data hiding in medical images(RDHMI),segmentation consists of only two regions:the focal and nonfocal regions.The focal region mainly contains information for diagnosis,while the nonfocal region serves as the monochrome background.The current traditional segmentation methods utilized in RDHMI are inaccurate for complex medical images,and manual segmentation is time-consuming,poorly reproducible,and operator-dependent.Implementing state-of-the-art deep learning(DL)models will facilitate key benefits,but the lack of domain-specific labels for existing medical datasets makes it impossible.To address this problem,this study provides labels of existing medical datasets based on a hybrid segmentation approach to facilitate the implementation of DL segmentation models in this domain.First,an initial segmentation based on a 33 kernel is performed to analyze×identified contour pixels before classifying pixels into focal and nonfocal regions.Then,several human expert raters evaluate and classify the generated labels into accurate and inaccurate labels.The inaccurate labels undergo manual segmentation by medical practitioners and are scored based on a hierarchical voting scheme before being assigned to the proposed dataset.To ensure reliability and integrity in the proposed dataset,we evaluate the accurate automated labels with manually segmented labels by medical practitioners using five assessment metrics:dice coefficient,Jaccard index,precision,recall,and accuracy.The experimental results show labels in the proposed dataset are consistent with the subjective judgment of human experts,with an average accuracy score of 94%and dice coefficient scores between 90%-99%.The study further proposes a ResNet-UNet with concatenated spatial and channel squeeze and excitation(scSE)architecture for semantic segmentation to validate and illustrate the usefulness of the proposed dataset.The results demonstrate the superior performance of the proposed architecture in accurately separating the focal and nonfocal regions compared to state-of-the-art architectures.Dataset information is released under the following URL:https://www.kaggle.com/lordamoah/datasets(accessed on 31 March 2025).
基金the Innovation Program of Shanghai Industrial Synergy(No.XTCX-KJ-2023-2-12)。
文摘Medical image segmentation is a crucial task in clinical applications.However,obtaining labeled data for medical images is often challenging.This has led to the appeal of semi-supervised learning(SSL),a technique adept at leveraging a modest amount of labeled data.Nonetheless,most prevailing SSL segmentation methods for medical images either rely on the single consistency training method or directly fine-tune SSL methods designed for natural images.In this paper,we propose an innovative semi-supervised method called multi-consistency training(MCT)for medical image segmentation.Our approach transcends the constraints of prior methodologies by considering consistency from a dual perspective:output consistency across different up-sampling methods and output consistency of the same data within the same network under various perturbations to the intermediate features.We design distinct semi-supervised loss regression methods for these two types of consistencies.To enhance the application of our MCT model,we also develop a dedicated decoder as the core of our neural network.Thorough experiments were conducted on the polyp dataset and the dental dataset,rigorously compared against other SSL methods.Experimental results demonstrate the superiority of our approach,achieving higher segmentation accuracy.Moreover,comprehensive ablation studies and insightful discussion substantiate the efficacy of our approach in navigating the intricacies of medical image segmentation.
