Murine cytomegalovirus（MCMV） IE3 protein is a multifunctional viral protein that inter-acts with several target proteins of both viral and host cellular origin.To investigate the biological func-tion of IE3 in the p...Murine cytomegalovirus（MCMV） IE3 protein is a multifunctional viral protein that inter-acts with several target proteins of both viral and host cellular origin.To investigate the biological func-tion of IE3 in the pathogenesis of the brain disorders caused by CMV,a screening for host cellular pro-teins that could interact with IE3 was performed.By yeast two-hybrid screening,ankyrin repeats do-main 17（Ankrd17,also known as Gtar） was identified as a host factor that could interact with IE3.This interaction was verified by yeast two-hybrid assay and chemiluminescent co-immunoprecipitaion.Map-ping analysis suggested that the 1-148 residues of IE3 were responsible for the interaction.These results suggested that the interaction between Ankrd17 and IE3 may play a key role in the pathogenesis of MCMV-associated disease.展开更多
This paper presents a compact microstrip patch antenna at operating frequency of 2.5 GHz. The radiating element of the proposed antenna consists of Swastika symbol patch using dielectric substrate 4.2, loss tangent 0....This paper presents a compact microstrip patch antenna at operating frequency of 2.5 GHz. The radiating element of the proposed antenna consists of Swastika symbol patch using dielectric substrate 4.2, loss tangent 0.0012 and having the same substrate height 1.6 mm. The antenna size is very compact (28.8 mm × 37.2 mm × 1.6 mm) and covers 1.696 GHz to 2.646 GHz and can be used for GSM and WLAN applications. Using IE3D software package of Zealand, the designed antenna is simulated. The computer simulation results show that the antenna can realize wideband characteristics having good impedance bandwidth of 43.758% (VSWR ≤ 2) for all resonant frequencies. Our aim is to reduce the size of the antenna as well as increase the impedance bandwidth.展开更多
基金supported by a grant from National Natural Sciences Foundation of China (No. 30671859)
文摘Murine cytomegalovirus（MCMV） IE3 protein is a multifunctional viral protein that inter-acts with several target proteins of both viral and host cellular origin.To investigate the biological func-tion of IE3 in the pathogenesis of the brain disorders caused by CMV,a screening for host cellular pro-teins that could interact with IE3 was performed.By yeast two-hybrid screening,ankyrin repeats do-main 17（Ankrd17,also known as Gtar） was identified as a host factor that could interact with IE3.This interaction was verified by yeast two-hybrid assay and chemiluminescent co-immunoprecipitaion.Map-ping analysis suggested that the 1-148 residues of IE3 were responsible for the interaction.These results suggested that the interaction between Ankrd17 and IE3 may play a key role in the pathogenesis of MCMV-associated disease.
文摘This paper presents a compact microstrip patch antenna at operating frequency of 2.5 GHz. The radiating element of the proposed antenna consists of Swastika symbol patch using dielectric substrate 4.2, loss tangent 0.0012 and having the same substrate height 1.6 mm. The antenna size is very compact (28.8 mm × 37.2 mm × 1.6 mm) and covers 1.696 GHz to 2.646 GHz and can be used for GSM and WLAN applications. Using IE3D software package of Zealand, the designed antenna is simulated. The computer simulation results show that the antenna can realize wideband characteristics having good impedance bandwidth of 43.758% (VSWR ≤ 2) for all resonant frequencies. Our aim is to reduce the size of the antenna as well as increase the impedance bandwidth.
