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Two novel gastric cancer-associated genes identified by differential display 被引量:4
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作者 YOU Han, XIAO Bing, CUI DaXiang, SHI YongQuan and FAN DaiMingKeywords stomach neoplasms gene clone +3 位作者 nucleotides sequence analysis in situ hybridization polymerase chain reaction RNA, messenger 《World Journal of Gastroenterology》 SCIE CAS CSCD 1998年第4期62-64,共3页
AIM To clone novel gastric cancer-associated genes and investigate their roles in gastric cancer occurrence.METHODS A method called differential display was used which allows the identification of differentially expre... AIM To clone novel gastric cancer-associated genes and investigate their roles in gastric cancer occurrence.METHODS A method called differential display was used which allows the identification of differentially expressed genes by using PAGE to display PCR-amplified cDNA fragments between gastric cancer cells and normal gastric mucosa cells. These fragments were cloned into plasmid vector pUC18. Homology analysis was made after sequencing these fragments.RESULTS Two novel genes were identified compared with sequences from GenBank. One was registered with the AD number AF 051783. In situ hybridization showed that these two novel genes expressed specifically in gastric cancer tissues.CONCLUSION The two novel genes obtained by differential display were confirmed to be gastric cancer-associated genes using in situ hybridization. 展开更多
关键词 DIFFERENTIAL identified GENES DISPLAY TWO cancer-associated
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Two Novel QTLs for Heading Date Are Identified Using a Set of Chromosome Segment Substitution Lines in Rice(Oryza sativa L.) 被引量:5
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作者 Guojing Shen Yongzhong Xing 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2014年第12期659-662,共4页
Heading date in rice is a typical quantitative trait controlled by multiple quantitative trait loci (QTLs). It is mainly regulated by environmental factors such as photoperiod and temperature (Izawa, 2007). Many Q... Heading date in rice is a typical quantitative trait controlled by multiple quantitative trait loci (QTLs). It is mainly regulated by environmental factors such as photoperiod and temperature (Izawa, 2007). Many QTLs for heading date have been identified using different mapping populations and methods (http:// www.gramene.org/qtl). Up to date, several major heading date QTLs have been cloned by map-based cloning strategy (Yano et al., 2000; Takahashi et al., 2001; Kojima et al., 2002; Doi et al., 2004; Xue et al., 2008; Wei et al., 2010; Yan et al., 展开更多
关键词 QTLS Two Novel QTLs for Heading Date Are identified Using a Set of Chromosome Segment Substitution Lines in Rice CSSLs Oryza sativa L
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Epithelial cell adhesion efficacy of a novel peptide identified by panning on a smooth titanium surface 被引量:2
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作者 Hidemichi Kihara David M.Kim +7 位作者 Masazumi Nagai Toshiki Nojiri Shigemi Nagai Chia-Yu Chen Cliff Lee Wataru Hatakeyama Hisatomo Kondo John Da Silva 《International Journal of Oral Science》 SCIE CAS CSCD 2018年第3期174-181,共8页
Epithelial attachment via the basal lamina on the tooth surface provides an important structural defence mechanism against bacterial invasion in combating periodontal disease. However, when considering dental implants... Epithelial attachment via the basal lamina on the tooth surface provides an important structural defence mechanism against bacterial invasion in combating periodontal disease. However, when considering dental implants, strong epithelial attachment does not exist throughout the titanium-soft tissue interface, making soft tissues more susceptible to peri-implant disease. This study introduced a novel synthetic peptide(A10) to enhance epithelial attachment. A10 was identified from a bacterial peptide display library and synthesized. A10 and protease-activated receptor 4-activating peptide(PAR4-AP, positive control) were immobilized on commercially pure titanium. The peptide-treated titanium showed high epithelial cell migration ability during incubation in platelet-rich plasma. We confirmed the development of dense and expanded BL(stained by Ln5) with pericellular junctions(stained by ZO1) on the peptide-treated titanium surface. In an adhesion assay of epithelial cells on A10-treated titanium, PAR4-AP-treated titanium, bovine root and non-treated titanium, A10-treated titanium and PAR4-AP-treated titanium showed significantly stronger adhesion than non-treated titanium. PAR4-AP-treated titanium showed significantly higher inflammatory cytokine release than non-treated titanium. There was no significant difference in inflammatory cytokine release between A10-treated and non-treated titanium. These results indicated that A10 could induce the adhesion and migration of epithelial cells with low inflammatory cytokine release. This novel peptide has a potentially useful application that could improve clinical outcomes with titanium implants and abutments by reducing or preventing peri-implant disease. 展开更多
关键词 PAR OBA Epithelial cell adhesion efficacy of a novel peptide identified by panning on a smooth titanium surface AP
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MLSI-RT: memorize LOS range measurements identified residual test location algorithm and performance analysis
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作者 马兵 邢建平 张军 《Journal of Shanghai University(English Edition)》 CAS 2011年第3期190-193,共4页
The dominant error source of mobile terminal location in wireless sensor networks (WSNs) is the non-line-of-sight (NLOS) propagation error. Among the algorithms proposed to mitigate the influence of NLOS propagati... The dominant error source of mobile terminal location in wireless sensor networks (WSNs) is the non-line-of-sight (NLOS) propagation error. Among the algorithms proposed to mitigate the influence of NLOS propagation error, residual test (RT) is an efficient one, however with high computational complexity (CC). An improved algorithm that memorizes the light of sight (LOS) range measurements (RMs) identified memorize LOS range measurements identified residual test (MLSI-RT) is presented in this paper to address this problem. The MLSI-RT is based on the assumption that when all RMs are from LOS propagations, the normalized residual follows the central Chi-Square distribution while for NLOS cases it is non-central. This study can reduce the CC by more than 90%. 展开更多
关键词 memorize LOS range measurements identified residual test (MLSI-RT) computational complexity (CC) nonline-of-sight (NLOS) residual test (RT) algorithm simplified residual test (SRT)
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AI-identified peptides boost jasmonate-mediated natural resistance against citrus Huanglongbing
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作者 Zhibo Zhao Shufeng Du +2 位作者 Daowen Wang Yong Wang Zheng Qing Fu 《Science Bulletin》 2025年第22期3708-3710,共3页
Citrus Huanglongbing(HLB),often referred to as greening disease,is a devastating bacterial disease that infects citrus trees.This disease results in blotchy mottling of leaves,premature fruit drop,twig dieback,stunted... Citrus Huanglongbing(HLB),often referred to as greening disease,is a devastating bacterial disease that infects citrus trees.This disease results in blotchy mottling of leaves,premature fruit drop,twig dieback,stunted growth,lower fruit yield,and misshapen,bitter or sour fruits[1].HLB has been detected in more than 58 countries across continents including Asia,the Americas,Africa,Oceania,and the Caribbean[2].It is the leading cause of citrus decline worldwide,significantly impacting citrus production in major producing nations such as Brazil,China,and the USA[2,3]. 展开更多
关键词 natural resistance ai identified peptides jasmonate mediated greening disease bacterial disease citrus huanglongbing hlb often citrus huanglongbing blotchy mottling
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Molecular uniting set identified characteristic(MUSIC): a promising strategy for purely organic RTP luminogens 被引量:1
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作者 Xiangfeng Shao 《Science China Chemistry》 SCIE EI CAS CSCD 2018年第8期975-976,共2页
The room temperature phosphorescences(RTP)are of growing interest owing to their promising applications in material science and bioimaging.To date,the lumiogens showing persistent RTP effect mainly contain the noble... The room temperature phosphorescences(RTP)are of growing interest owing to their promising applications in material science and bioimaging.To date,the lumiogens showing persistent RTP effect mainly contain the noble metals which have the shortcomings such as high cost,potential toxicity.The exploration of metal free luminogens,i.e.,purely organic RTP luminogens,is thus of great importance for the community. 展开更多
关键词 RTP Molecular uniting set identified characteristic a promising strategy for purely organic RTP luminogens MUSIC
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QUALITY CONTROL MARKERS OF DU-HUO-JI-SHENG-TANG IDENTIFIED ACCORDING TO ANTI-INFLAMMATORY EFFECTS
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作者 Po-Wei Tsai Lih-Geeng Chen +2 位作者 Chao-Hsin Chen Sung-Hui Tseng Ching-Chiung Wang 《World Journal of Traditional Chinese Medicine》 2015年第4期105-105,共1页
The Du-Huo-Ji-Sheng-Tang(DHJST)is the top commercial concentrated aqueous extract used in clinics for treating osteoarthritis.However,choosing the quality control markers for DHJST is an important problem for herbal m... The Du-Huo-Ji-Sheng-Tang(DHJST)is the top commercial concentrated aqueous extract used in clinics for treating osteoarthritis.However,choosing the quality control markers for DHJST is an important problem for herbal medicine industry.In this study,DHJST was divided into three groups according to the medical philosophy of traditional Chinese medicine(TCM),such as Si-Wu-Tang(SWT),wind-dampness herbs(WDH)and tonifying 展开更多
关键词 SWT QUALITY CONTROL MARKERS OF DU-HUO-JI-SHENG-TANG identified ACCORDING TO ANTI-INFLAMMATORY EFFECTS
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China's Major Minerals in 2016 Are Identified,With Overal Resource Reserves Continuing to Grow
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《China Nonferrous Metals Monthly》 2017年第9期4-5,共2页
On August 22,the reporter learned from MLR’s Press Conference for Identified Reserves of Mineral Resources of China in2016 that,China’s investment in mining fixed assets and geological exploration had declined for f... On August 22,the reporter learned from MLR’s Press Conference for Identified Reserves of Mineral Resources of China in2016 that,China’s investment in mining fixed assets and geological exploration had declined for four consecutive years by 2016,and resource reserves growth rate had slowed down due to other reasons such as downturn 展开更多
关键词 In China’s Major Minerals in 2016 Are identified With Overal Resource Reserves Continuing to Grow
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Cloning of qHD8^(BAS),a Quantitative Trait Locus Regulating Heading Date in Rice
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作者 ZHANG Zhengjiu BIAN Ying +3 位作者 YANG Ruoju ZHANG Xiaobo GONG Junyi FAN Jiongjiong 《Rice science》 2025年第3期283-286,I0005-I0011,共11页
Heading date is one of the most important agronomic traits that directly affect rice yield and determines the regional adaptability in specific growing environments.As a short-day plant,rice can grow under long-day(LD... Heading date is one of the most important agronomic traits that directly affect rice yield and determines the regional adaptability in specific growing environments.As a short-day plant,rice can grow under long-day(LD)conditions due to the synergistic regulation of many photosensitive genes.Using a set of chromosome segment substitution lines(CSSLs)with the indica cultivar Huanghuazhan(HHZ)as the recipient parent and Basmati Surkh 89-15(BAS)as the donor parent,we identified a QTL locus. 展开更多
关键词 chromosome segment substitution lines cssls agronomic traits identified qtl locus indica cultivar quantitative trait locus synergistic regulation many photosensitive genesusing heading date CLONING
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Weak feedback self-mixing interference fringe slope discrimination method based on deep learning
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作者 ZHAO Yan LIN Maohua +3 位作者 DU Shengzhi TONG Jigang LIU Bin HAN Fangfang 《Optoelectronics Letters》 2025年第11期684-689,共6页
In order to identify the tilt direction of the self-mixing signals under weak feedback regime interfered by noise,a deep learning method is proposed.The one-dimensional U-Net(1D U-Net)neural network can identify the d... In order to identify the tilt direction of the self-mixing signals under weak feedback regime interfered by noise,a deep learning method is proposed.The one-dimensional U-Net(1D U-Net)neural network can identify the direction of the self-mixing fringes accurately and quickly.In the process of measurement,the measurement signal can be normalized and then the neural network can be used to discriminate the direction.Simulation and experimental results show that the proposed method is suitable for self-mixing interference signals with noise in the whole weak feedback regime,and can maintain a high discrimination accuracy for signals interfered by 5 dB large noise.Combined with fringe counting method,accurate and rapid displacement reconstruction can be realized. 展开更多
关键词 weak feedback identify direction measurement signal DISCRIMINATE self mixing interference weak feedback regime neural network identify tilt direction
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Unravelling the deception:identifying cheiro-oral syndrome in the emergency department——case reports
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作者 Yongyin Qiu Shu Fang Ho 《World Journal of Emergency Medicine》 2025年第2期192-194,共3页
Patients with cheiro-oral syndrome(COS) often present with minor perioral and upper extremity sensory disturbances,which can be easily overlooked in busy emergency departments(EDs).^([1]) COS,a rare spectrum of stroke... Patients with cheiro-oral syndrome(COS) often present with minor perioral and upper extremity sensory disturbances,which can be easily overlooked in busy emergency departments(EDs).^([1]) COS,a rare spectrum of stroke syndromes,necessitates expeditious and aggressive modification of risk factors. 展开更多
关键词 ORAL identifying DEPARTMENT
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Sharing gray academic literature with ResearchGate DOIs:Increased discoverability but inaccurate metadata
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作者 Enrique Orduña-Malea 《Journal of Data and Information Science》 2025年第4期44-65,共22页
Purpose:To describe the characteristics of research outputs using persistent identifiers generated by ResearchGate to gain insight into what publications are shared and disseminated through this functionality,revealin... Purpose:To describe the characteristics of research outputs using persistent identifiers generated by ResearchGate to gain insight into what publications are shared and disseminated through this functionality,revealing their academic and non-academic impact.Design/methodology/approach:A total of 1,092,934 RG-DOIs were collected,using the DataCite API,along with bibliographic metadata for the associated registered output(RG-DOI publications).The subsequent analysis evaluated the publication date,document type,and language.These values were crossreferenced against the full text of a random sample of 666 records to verify accuracy.Findings:RG-DOIs have served primarily to identify and make accessible scholarly gray literature,including posters,presentations,conference papers,and theses,with notable emphasis on publications in Spanish and Portuguese.Around 41,000 citations from Web of Science indexed publications to RG publications are evidence of their infrequent but perceptible use in scholarly discourse.The declining number of registrations of RG-DOIs observed may indicate a shift in researcher preferences to alternative platforms for DOI generation.Research limitations:The study uncovered substantial inconsistencies in DataCite metadata,which can be attributed to the automated DOI registration process and internal changes in the available document types on ResearchGate.Practical implications:The study encountered challenges in conducting a quantitative analysis due to inconsistencies in the metadata.These have potential implications for researchers,practitioners,and librarians relying on RG-DOIs to conduct bibliometric or bibliographic analysis.Originality/value:This study is the first comprehensive analysis of RG-DOIs and,as such,provides a unique perspective into academic gray literature.It also sheds light on the quality of ResearchGate data transmitted to DataCite when registering DOIs. 展开更多
关键词 Article-level metrics Permanent identifiers ResearchGate Social academic networking sites Social media metrics
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TGI-FPR: An Improved Multi-Label Password Guessing Model
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作者 Wei Ou Shuai Liu +3 位作者 Mengxue Pang Jianqiang Ma Qiuling Yue Wenbao Han 《Computers, Materials & Continua》 2025年第7期463-490,共28页
TarGuess-I is a leading model utilizing Personally Identifiable Information for online targeted password guessing.Due to its remarkable guessing performance,the model has drawn considerable attention in password secur... TarGuess-I is a leading model utilizing Personally Identifiable Information for online targeted password guessing.Due to its remarkable guessing performance,the model has drawn considerable attention in password security research.However,through an analysis of the vulnerable behavior of users when constructing passwords by combining popular passwords with their Personally Identifiable Information,we identified that the model fails to consider popular passwords and frequent substrings,and it uses overly broad personal information categories,with extensive duplicate statistics.To address these issues,we propose an improved password guessing model,TGI-FPR,which incorporates three semantic methods:(1)identification of popular passwords by generating top 300 lists from similar websites,(2)use of frequent substrings as new grammatical labels to capture finer-grained password structures,and(3)further subdivision of the six major categories of personal information.To evaluate the performance of the proposed model,we conducted experiments on six large-scale real-world password leak datasets and compared its accuracy within the first 100 guesses to that of TarGuess-I.The results indicate a 2.65%improvement in guessing accuracy. 展开更多
关键词 Password analysis personally identifiable information frequent substring password guessing model
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Commentary on“Delayed covering causes the accumulation of motile sperm,leading to overestimation of sperm concentration and motility with a Makler counting chamber”
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作者 Elisabetta Tosti 《Asian Journal of Andrology》 2025年第1期135-136,共2页
The analysis of the ejaculate,better known as spermiogram,represents the first and main step to identify whether a series of sperm quality parameters are within the norm and therefore are consistent with normal sperm ... The analysis of the ejaculate,better known as spermiogram,represents the first and main step to identify whether a series of sperm quality parameters are within the norm and therefore are consistent with normal sperm fertilizing capacity.Among these,sperm concentration and motility are the first parameters to be evaluated through an estimation carried out by expert examiners. 展开更多
关键词 identify whether series sperm quality parameters within delayed covering accumulation MOTILITY OVERESTIMATION makler counting chamber motile sperm sperm concentration
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Topology-driven directed synthesis of metal-organic frameworks
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作者 Guoying Han Qazi Mohammad Junaid Xiao Feng 《Chinese Journal of Structural Chemistry》 2025年第3期10-11,共2页
Metal-organic frameworks(MOFs)have garnered widespread attention due to their designability and diversity[1].Customization has always been a pursuit of chemists and materials scientists[2].Topology provides a means of... Metal-organic frameworks(MOFs)have garnered widespread attention due to their designability and diversity[1].Customization has always been a pursuit of chemists and materials scientists[2].Topology provides a means of abstracting the complex structures of MOFs by identifying and classifying the fundamental building units and connection patterns,simplifying the understanding of MOF structures[3]. 展开更多
关键词 directed synthesis TOPOLOGY metal organic frameworks identifying classifying fundamental building units
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Dual-branch spatial-temporal decoupled fusion transformer for safety action recognition in smart grid substation
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作者 HAO Yu ZHENG Hao +3 位作者 WANG Tongwen WANG Yu SUN Wei ZHANG Shujuan 《Optoelectronics Letters》 2025年第8期507-512,共6页
Smart grid substation operations often take place in hazardous environments and pose significant threats to the safety of power personnel.Relying solely on manual supervision can lead to inadequate oversight.In respon... Smart grid substation operations often take place in hazardous environments and pose significant threats to the safety of power personnel.Relying solely on manual supervision can lead to inadequate oversight.In response to the demand for technology to identify improper operations in substation work scenarios,this paper proposes a substation safety action recognition technology to avoid the misoperation and enhance the safety management.In general,this paper utilizes a dual-branch transformer network to extract spatial and temporal information from the video dataset of operational behaviors in complex substation environments.Firstly,in order to capture the spatial-temporal correlation of people's behaviors in smart grid substation,we devise a sparse attention module and a segmented linear attention module that are embedded into spatial branch transformer and temporal branch transformer respectively.To avoid the redundancy of spatial and temporal information,we fuse the temporal and spatial features using a tensor decomposition fusion module by a decoupled manner.Experimental results indicate that our proposed method accurately detects improper operational behaviors in substation work scenarios,outperforming other existing methods in terms of detection and recognition accuracy. 展开更多
关键词 identify improper operations manual supervision avoid misoperation spatial temporal substation safety action recognition technology dual branch decoupled fusion enhance safety managementin
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区分物理变化和化学变化
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作者 朱利香 《疯狂英语(双语世界)》 2025年第2期56-58,80,共4页
Can you identify physical and chemical changes?Have a try!
关键词 identify physical chemical changeshave chemical change physical change
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Predictors of Short-term Relapse after Successful Smoking Cessation among Patients Attending Smoking Cessation Clinics in China,2019–2021:A Retrospective Cohort Study
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作者 Li Xie Shiwei Liu +1 位作者 Xinying Zeng Lin Xiao 《Biomedical and Environmental Sciences》 2025年第12期1544-1549,共6页
The Chinese government promotes smoking cessation through smoking cessation clinics(SCCs).This study aimed to identify factors associated with relapse and provide evidence to inform interventions that reduce relapse r... The Chinese government promotes smoking cessation through smoking cessation clinics(SCCs).This study aimed to identify factors associated with relapse and provide evidence to inform interventions that reduce relapse risk.Participants were SCC patients aged≥18 years who enrolled between June 2019 and December 2021,completed follow-up assessments at one and three months,and reported abstinence at one month.Short-term relapse was defined as self-reported smoking at the three-month follow-up.Treatments included counseling,first-line cessation medications,and traditional Chinese medicine(TCM).Logistic regression was used to identify factors associated with short-term relapse.Among 10,724 eligible SCC patients,11.6%experienced short-term relapse.Factors positively associated with relapse included the number of previous quit attempts(1–5 attempts:OR=1.422,95%CI:1.254–1.613,>5 attempts:OR=1.382,95%CI:1.057–1.808),high perceived difficulty in quitting(OR=1.297,95%CI:1.061–1.586),and moderate(OR=1.383,95%CI:1.174–1.629)or weak(OR=1.517,95%CI:1.251–1.841)willingness to quit.Factors negatively associated with relapse included having a college degree or higher(OR=0.796;95%CI:0.650–0.973),high confidence in quitting(OR=0.786;95%CI:0.629–0.983),and use of TCM(OR=0.276;95%CI:0.158–0.482).Enhancing self-efficacy in quitting appears crucial for preventing short-term relapse.The use of TCM may reduce relapse risk and warrants further investigation. 展开更多
关键词 identify factors associated relapse Chinese patients smoking cessation logistic regression smoking cessation clinics smoking cessation clinics sccs PREDICTORS RELAPSE
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System Structure Analysis of the Factors Influencing the“Energy Trilemma”in China’s Natural Gas Industry
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作者 Li Qiaochu Luo Pingya Zhang Peng 《China Oil & Gas》 2025年第3期34-40,共7页
Clarifying the system structure of various influencing factors is a crucial prerequisite for identifying the key action point to address the“Energy Trilemma”in China’s natural gas industry.Based on the three-dimens... Clarifying the system structure of various influencing factors is a crucial prerequisite for identifying the key action point to address the“Energy Trilemma”in China’s natural gas industry.Based on the three-dimensional system of“safety and stability-economic feasibility-low-carbon and environmental protection,”an influencing factor system for the“Energy Trilemma”in the natural gas industry is constructed. 展开更多
关键词 natural gas safety stability natural gas industry influencing factor system energy trilemma identifying key action point low carbon environmental protection economic feasibility
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Late Ediacaran Subduction Initiation in the Southern Altaids
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作者 Bo Liu Baofu Han 《Journal of Earth Science》 2025年第6期2803-2806,共4页
0 INTRODUCTION Initial subduction involves the complex process of oceanic lithosphere first inserting beneath oceanic or continental lithosphere(Chen et al.,2024;Yang et al.,2022;Stern and Gerya,2018).The modern Izu-B... 0 INTRODUCTION Initial subduction involves the complex process of oceanic lithosphere first inserting beneath oceanic or continental lithosphere(Chen et al.,2024;Yang et al.,2022;Stern and Gerya,2018).The modern Izu-Bonin-Mariana(IBM)initial subduction system suggests that identifying the earliest ophiolites,arc igneous and metamorphic complexes(e.g.,blueschist,eclogites)can reconstruct ancient initial subduction systems(Yao et al.,2021;Ishizuka et al.,2011).However,knowledge of ancient subduction initiation is often limited due to poor exposures of rocks formed during the earliest stages of subduction(Chen et al.,2024;Cawood et al.,2009). 展开更多
关键词 oceanic continental lithosphere chen identifying earliest ophiolitesarc igneous metamorphic complexes egblueschisteclogites can subduction initiation arc igneous metamorphic complexes oceanic lithosphere first inserting OPHIOLITES initial subduction BLUESCHIST
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