The integration of the intelligent reflecting surface(IRS)with simultaneous wireless information and power transfer(SWIPT)has emerged as a cost-effective and efficient solution to enhance the performance of informatio...The integration of the intelligent reflecting surface(IRS)with simultaneous wireless information and power transfer(SWIPT)has emerged as a cost-effective and efficient solution to enhance the performance of information and energy transfer.In this research,a hybrid active/passive IRS-assisted SWIPT system is proposed.Specifically,an active IRS(AIRS)and a passive IRS(PIRS)are deployed in the SWIPT system to facilitate a multiantenna base station(BS)in simultaneously delivering information and energy to multiple information users(IUs)and energy users(EUs).The objective is to maximize the sum throughput by jointly optimizing the transmitter beamforming and the reflection coefficient matrices of the AIRS and the PIRS while satisfying the transmitter power constraints,the energy harvesting(EH)requirements of EUs,and the AIRS amplification power limitations.However,the optimization variables are highly coupled and cannot be solved directly.To tackle this complex problem,we propose an efficient algorithm based on alternating optimization(AO)and semi-definite relaxation(SDR)techniques to obtain high-quality solutions.Simulation results demonstrate that the hybrid active/passive IRSassisted SWIPT system significantly enhances throughput performance and outperforms benchmark systems.展开更多
This study aimed to investigate the effects of infant feces-derived Bifidobacterium breve CCFM1078 on rheumatoid cachexia(RC).Twenty-four female Wistar rats were assigned to 3 groups:CON group(normal saline by gavage)...This study aimed to investigate the effects of infant feces-derived Bifidobacterium breve CCFM1078 on rheumatoid cachexia(RC).Twenty-four female Wistar rats were assigned to 3 groups:CON group(normal saline by gavage),CIA group(collagen-induced arthritis(CIA),normal saline by gavage),and CCFM1078 group(CIA,3×10^(9)CFU/(rat·day)B.breve CCFM1078 gavage).The results demonstrated that B.breve CCFM1078 not only improved skeletal muscle function in CIA rats,but also modulated the gut microbiota,skeletal muscle metabolism and hormone levels,reduced inflammation in the knee joint and skeletal muscles,decreased activity of the nuclear factor κB(NF-κB)inflammatory signaling pathway,enhanced the insulin receptor substrate 1(IRS1)/phosphatidylinositol 3-kinase/protein kinase(PI3K/Akt)signaling pathway,promoted skeletal muscle differentiation,and maintained skeletal muscle fiber diameter,consequently slowing down the progression of RC.These findings suggested that B.breve CCFM1078 may have a beneficial role as part of a dietary intervention for RC,enhancing overall therapeutic effects.展开更多
高剂量率(High Dose Rate,HDR)近距离放射治疗在现代临床近距离放疗中得到广泛应用,临床实践依赖于^(192)Ir源的精确剂量学参数。由于不同放射源设计各异,各型号放射源需特定的剂量学参数。尽管国际上已针对^(192)Ir源进行了广泛研究,...高剂量率(High Dose Rate,HDR)近距离放射治疗在现代临床近距离放疗中得到广泛应用,临床实践依赖于^(192)Ir源的精确剂量学参数。由于不同放射源设计各异,各型号放射源需特定的剂量学参数。尽管国际上已针对^(192)Ir源进行了广泛研究,但针对原子高科股份有限公司生产的HDR ^(192)Ir源的国内研究较少。为了计算国产HDR ^(192)Ir源的剂量学参数,依据美国医学物理师协会(American Association of Physicists in Medicine,AAPM)TG43-U1推荐的剂量学参数计算方法,使用蒙特卡罗模拟软件建立^(192)Ir源的详细结构模型进行模拟计算。模拟结果显示:剂量率常数为1.105 cGy·h^(-1)·U^(-1),与文献值差异小于1.2%;单位活度空气比释动能率为9.788×10^(-8) U·Bq^(-1),差异为0.23%;径向剂量函数和各向异性函数结果与文献一致。结果表明,该模型对于国产HDR ^(192)Ir源的临床应用,具有一定的指导意义。展开更多
基金National Natural Science Foundation of China(No.62301141)。
文摘The integration of the intelligent reflecting surface(IRS)with simultaneous wireless information and power transfer(SWIPT)has emerged as a cost-effective and efficient solution to enhance the performance of information and energy transfer.In this research,a hybrid active/passive IRS-assisted SWIPT system is proposed.Specifically,an active IRS(AIRS)and a passive IRS(PIRS)are deployed in the SWIPT system to facilitate a multiantenna base station(BS)in simultaneously delivering information and energy to multiple information users(IUs)and energy users(EUs).The objective is to maximize the sum throughput by jointly optimizing the transmitter beamforming and the reflection coefficient matrices of the AIRS and the PIRS while satisfying the transmitter power constraints,the energy harvesting(EH)requirements of EUs,and the AIRS amplification power limitations.However,the optimization variables are highly coupled and cannot be solved directly.To tackle this complex problem,we propose an efficient algorithm based on alternating optimization(AO)and semi-definite relaxation(SDR)techniques to obtain high-quality solutions.Simulation results demonstrate that the hybrid active/passive IRSassisted SWIPT system significantly enhances throughput performance and outperforms benchmark systems.
基金supported by the National Natural Science Foundation of China(32021005)111 project(BP0719028)the Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province.
文摘This study aimed to investigate the effects of infant feces-derived Bifidobacterium breve CCFM1078 on rheumatoid cachexia(RC).Twenty-four female Wistar rats were assigned to 3 groups:CON group(normal saline by gavage),CIA group(collagen-induced arthritis(CIA),normal saline by gavage),and CCFM1078 group(CIA,3×10^(9)CFU/(rat·day)B.breve CCFM1078 gavage).The results demonstrated that B.breve CCFM1078 not only improved skeletal muscle function in CIA rats,but also modulated the gut microbiota,skeletal muscle metabolism and hormone levels,reduced inflammation in the knee joint and skeletal muscles,decreased activity of the nuclear factor κB(NF-κB)inflammatory signaling pathway,enhanced the insulin receptor substrate 1(IRS1)/phosphatidylinositol 3-kinase/protein kinase(PI3K/Akt)signaling pathway,promoted skeletal muscle differentiation,and maintained skeletal muscle fiber diameter,consequently slowing down the progression of RC.These findings suggested that B.breve CCFM1078 may have a beneficial role as part of a dietary intervention for RC,enhancing overall therapeutic effects.
文摘高剂量率(High Dose Rate,HDR)近距离放射治疗在现代临床近距离放疗中得到广泛应用,临床实践依赖于^(192)Ir源的精确剂量学参数。由于不同放射源设计各异,各型号放射源需特定的剂量学参数。尽管国际上已针对^(192)Ir源进行了广泛研究,但针对原子高科股份有限公司生产的HDR ^(192)Ir源的国内研究较少。为了计算国产HDR ^(192)Ir源的剂量学参数,依据美国医学物理师协会(American Association of Physicists in Medicine,AAPM)TG43-U1推荐的剂量学参数计算方法,使用蒙特卡罗模拟软件建立^(192)Ir源的详细结构模型进行模拟计算。模拟结果显示:剂量率常数为1.105 cGy·h^(-1)·U^(-1),与文献值差异小于1.2%;单位活度空气比释动能率为9.788×10^(-8) U·Bq^(-1),差异为0.23%;径向剂量函数和各向异性函数结果与文献一致。结果表明,该模型对于国产HDR ^(192)Ir源的临床应用,具有一定的指导意义。