Background:In response to the need for research clearly demonstrating the net effect of smoking cessation on mental health status,considering the causal relationship between smoking cessation and changes in mental hea...Background:In response to the need for research clearly demonstrating the net effect of smoking cessation on mental health status,considering the causal relationship between smoking cessation and changes in mental health status,this study was undertaken.Thus,this study aimed to examine the net effect of short-term smoking cessation on five specific mental health metrics and the overall mental health status score.Methods:We used data from the first wave of the Korean Health Panel(KHP)Survey(2011–2013,2016–2018)and focused on men aged 19 years and older,to explore the effects of smoking cessation.We compared mental health status before and after cessation among current non-smokers who had quit smoking and continuous smokers.We ensured homogeneity between the two groups via inverse probability of treatment weighting(IPTW)and employed a difference-in-differences(DID)analysis to assess changes in mental health status.This study controlled for factors that could influence mental health and explored the net effect of short-term smoking cessation through difference-in-differences model using multiple regression analysis.Results:The results showed that short-term smoking cessation significantly alleviated mental and physical stress(p<0.1),reduced experiences of frustration(p<0.01),and improved the overall mental health status score(p<0.1).Conclusion:Thus,these results highlight a meaningful link between positive health behavior changes,such as smoking cessation,and enhanced mental health.Moreover,the application of temporal variables further improved the understanding of the causal relationship between health behaviors and mental health.展开更多
Background:Laparoscopic resection(LR)of perihilar cholangiocarcinoma(pCCA)is still in the exploratory stage due to its exacting technical requirements,and its feasibility remains controversial.The objective of this st...Background:Laparoscopic resection(LR)of perihilar cholangiocarcinoma(pCCA)is still in the exploratory stage due to its exacting technical requirements,and its feasibility remains controversial.The objective of this study was to compare the short-and long-term outcomes of LR and open resection(OR)of pCCA.Methods:This study analyzed the data of pCCA patients who underwent LR or OR from January 2012 to January 2020 at Southwest Hospital.Inverse probability of treatment weighting(IPTW)and propensity score matching(PSM)were used to balance the baseline characteristics between the LR and OR groups.The short-and long-term outcomes were compared between the LR and OR groups.Results:Forty-five patients in the LR group and 243 in the OR group were analyzed.After IPTW and PSM,the amount of intraoperative blood loss,incidence of surgical site infections(SSIs),length of stay(LOS),and number of perioperative blood transfusions(PBTs)were significantly lower in the LR group than in the OR group(after IPTW:P<0.001,P=0.009,P=0.01,P<0.001 respectively;after PSM:P<0.001,P=0.003,P=0.03,P=0.04 respectively).Only after IPTW was the 30-day mortality rate significantly lower in the LR group than in the OR group(P=0.005).There was no significant difference in overall survival(OS)or recurrence-free survival(RFS)between the two groups after IPTW or PSM.Conclusions:LR of pCCA is an achievable procedure whose long-term outcomes are similar to those of OR,and LR outperforms OR in short-term outcomes such as intraoperative blood loss,SSI,LOS,30-day mortality,and PBTs.It is believed that it is safe and feasible to treat pCCA with LR after rigorous patient selection.展开更多
文摘Background:In response to the need for research clearly demonstrating the net effect of smoking cessation on mental health status,considering the causal relationship between smoking cessation and changes in mental health status,this study was undertaken.Thus,this study aimed to examine the net effect of short-term smoking cessation on five specific mental health metrics and the overall mental health status score.Methods:We used data from the first wave of the Korean Health Panel(KHP)Survey(2011–2013,2016–2018)and focused on men aged 19 years and older,to explore the effects of smoking cessation.We compared mental health status before and after cessation among current non-smokers who had quit smoking and continuous smokers.We ensured homogeneity between the two groups via inverse probability of treatment weighting(IPTW)and employed a difference-in-differences(DID)analysis to assess changes in mental health status.This study controlled for factors that could influence mental health and explored the net effect of short-term smoking cessation through difference-in-differences model using multiple regression analysis.Results:The results showed that short-term smoking cessation significantly alleviated mental and physical stress(p<0.1),reduced experiences of frustration(p<0.01),and improved the overall mental health status score(p<0.1).Conclusion:Thus,these results highlight a meaningful link between positive health behavior changes,such as smoking cessation,and enhanced mental health.Moreover,the application of temporal variables further improved the understanding of the causal relationship between health behaviors and mental health.
基金supported by Chongqing‘Direct Ph.D.Express’Research Project(CSTB2022BSXM-JCX0017)Chongqing Natural Science Foundation General Project(CSTB2022NSCQ-MSX0204).
文摘Background:Laparoscopic resection(LR)of perihilar cholangiocarcinoma(pCCA)is still in the exploratory stage due to its exacting technical requirements,and its feasibility remains controversial.The objective of this study was to compare the short-and long-term outcomes of LR and open resection(OR)of pCCA.Methods:This study analyzed the data of pCCA patients who underwent LR or OR from January 2012 to January 2020 at Southwest Hospital.Inverse probability of treatment weighting(IPTW)and propensity score matching(PSM)were used to balance the baseline characteristics between the LR and OR groups.The short-and long-term outcomes were compared between the LR and OR groups.Results:Forty-five patients in the LR group and 243 in the OR group were analyzed.After IPTW and PSM,the amount of intraoperative blood loss,incidence of surgical site infections(SSIs),length of stay(LOS),and number of perioperative blood transfusions(PBTs)were significantly lower in the LR group than in the OR group(after IPTW:P<0.001,P=0.009,P=0.01,P<0.001 respectively;after PSM:P<0.001,P=0.003,P=0.03,P=0.04 respectively).Only after IPTW was the 30-day mortality rate significantly lower in the LR group than in the OR group(P=0.005).There was no significant difference in overall survival(OS)or recurrence-free survival(RFS)between the two groups after IPTW or PSM.Conclusions:LR of pCCA is an achievable procedure whose long-term outcomes are similar to those of OR,and LR outperforms OR in short-term outcomes such as intraoperative blood loss,SSI,LOS,30-day mortality,and PBTs.It is believed that it is safe and feasible to treat pCCA with LR after rigorous patient selection.
