The aim of this present study was to explore the expression and clinical significance of O-linked N-acetylglucosamine（O-GlcNAc） transferase（OGT） and enzymatic O-linked glycosylation（O-GlcNAcation） through the ad...The aim of this present study was to explore the expression and clinical significance of O-linked N-acetylglucosamine（O-GlcNAc） transferase（OGT） and enzymatic O-linked glycosylation（O-GlcNAcation） through the addition of O-linked-β-N-acetylglucosamine in esophageal squamous cell carcinoma.OGT expression and O-GlcNAcation in 40 samples from patients with esophageal squamous cell carcinoma was detected by immunohistochemical staining with anti-OGT antib ody and O-GlcNAc-specific antibody RL 2,respectively.The relationship between pathological and clinical factors of patients was analyzed.We found that the expression of OGT was higher in esophageal squamous cell carcinoma samples compared to the normal tissues.RL 2 antibody level was positively correlated with OGT expression,and the metastasis of lymph node,which means the level of O-GlcNAcation was high and related to the metastasis of lymph node in esophageal squamous cell carcinoma.In conclusion,OGT activation is the main reason for promoting the level of O-GlcNAcation in esophageal squamous cell carcinoma.O-GlcNAcylation may play an important role in esophageal squamous cell carcinoma.展开更多
Material structures and device structures of a 100-GHz InP based transferred-electron device are designed in this paper. In order to successfully fabricate the Gunn devices operating at 100 GHz, the InP substrate was ...Material structures and device structures of a 100-GHz InP based transferred-electron device are designed in this paper. In order to successfully fabricate the Gunn devices operating at 100 GHz, the InP substrate was entirely removed by mechanical thinning and wet etching. The Gunn device was connected to a tripler link and a high RF （radio frequency） output with power of 2 mW working at 300 GHz was obtained, which is high enough for applications in current military electronic systems.展开更多
The vibrational spectra of both pure DPPC liposomes and DPPC multilayers reconstituted with Ge-132 are reported as a function of temperature from 290 to 330K.The results show that the addition of Ge-132 results in sup...The vibrational spectra of both pure DPPC liposomes and DPPC multilayers reconstituted with Ge-132 are reported as a function of temperature from 290 to 330K.The results show that the addition of Ge-132 results in suppression of the pretransition behavior and reduction of temperature of the main transition for reconstituted system.The results also show that the degree of rigidity of the acyl chain in the presence of Ge-132 is lower than that in pure DPPC dispersion within the investigated temperature range.展开更多
A novel algorithm for active noise control systems based on frequency selective filters （FSFANC） is presented in the paper. The FSFANC aims at the multi-tonal noise attenuation problem. One FSFANC system copes with ...A novel algorithm for active noise control systems based on frequency selective filters （FSFANC） is presented in the paper. The FSFANC aims at the multi-tonal noise attenuation problem. One FSFANC system copes with one of the tonal components, and several FSFANC systems can run independently in paralld to cancel the selected multiple tones. The proposed algorithm adopts a simple structure with only two coefficients that can be explained as the real and imaginary parts of the structure to model the secondary path, and estimates the secondary path by injecting sinusoidal identification signals. Theoretical analysis and laboratory experiments show that the proposed algorithm possesses stone advantages, such as simpler structure, less computational burden, greater stability, and fast converging speed.展开更多
Objective: To observe the therapeutic effect of the integrated acupuncture-moxibustio n and herbal therapies for facial paralysis. Methods: A total of 68 cases of facial paralysis were treated by integration of acupun...Objective: To observe the therapeutic effect of the integrated acupuncture-moxibustio n and herbal therapies for facial paralysis. Methods: A total of 68 cases of facial paralysis were treated by integration of acupunct ure-moxibustion and herbal therapies. For acu-moxibustion, Yifeng (翳风 TE 17) , Dicang (地仓 ST 4), Jiache (颊车 ST 6), Yangbai (阳白 GB 14), Hegu (合谷 LI 4), etc. were used. In addition, for facial palsy patients with wind-phlegm blockin g meridian-collaterals and wind-stirring due to yin defi ciency types in the acute stage, Modified Qian Zheng San (牵正散 Powder for Treating Wry-mouth) and Modi f ied Zhen Gan Xi Feng Tang (镇肝熄风汤 Tranquilizing Liver-wind Decoction) were u sed respectively; and for those in convalescent stage and sequela stage, Modifie d Danggui Bu Xue Tang (当归补血汤 Ghinese Angelica Decoction for Replenishing Bl ood) + Qian Zheng San (Powder for Treating Wry-mouth) and Modified Bu Yang Hu an Wu Tang (补阳还五汤 Decoction Invigorating Yang for Recuperation) were employed. Results: After the treatment, the curative rate of the 68 cases a ccounted for 90 % of the total cases, the remarkably effective 6%, the improved 3% and the poor 1% respectively. Conclusion: The therapeutic effectiveness of the integrated tre atment of acupuncture-moxibustion and herbal therapies for facial paralysis is certain.展开更多
文摘The aim of this present study was to explore the expression and clinical significance of O-linked N-acetylglucosamine（O-GlcNAc） transferase（OGT） and enzymatic O-linked glycosylation（O-GlcNAcation） through the addition of O-linked-β-N-acetylglucosamine in esophageal squamous cell carcinoma.OGT expression and O-GlcNAcation in 40 samples from patients with esophageal squamous cell carcinoma was detected by immunohistochemical staining with anti-OGT antib ody and O-GlcNAc-specific antibody RL 2,respectively.The relationship between pathological and clinical factors of patients was analyzed.We found that the expression of OGT was higher in esophageal squamous cell carcinoma samples compared to the normal tissues.RL 2 antibody level was positively correlated with OGT expression,and the metastasis of lymph node,which means the level of O-GlcNAcation was high and related to the metastasis of lymph node in esophageal squamous cell carcinoma.In conclusion,OGT activation is the main reason for promoting the level of O-GlcNAcation in esophageal squamous cell carcinoma.O-GlcNAcylation may play an important role in esophageal squamous cell carcinoma.
基金Project supported by the Main Direction Program of Knowledge Innovation of the Chinese Academy of Sciences(Grant No.2A2011YYYJ-1123)
文摘Material structures and device structures of a 100-GHz InP based transferred-electron device are designed in this paper. In order to successfully fabricate the Gunn devices operating at 100 GHz, the InP substrate was entirely removed by mechanical thinning and wet etching. The Gunn device was connected to a tripler link and a high RF （radio frequency） output with power of 2 mW working at 300 GHz was obtained, which is high enough for applications in current military electronic systems.
文摘The vibrational spectra of both pure DPPC liposomes and DPPC multilayers reconstituted with Ge-132 are reported as a function of temperature from 290 to 330K.The results show that the addition of Ge-132 results in suppression of the pretransition behavior and reduction of temperature of the main transition for reconstituted system.The results also show that the degree of rigidity of the acyl chain in the presence of Ge-132 is lower than that in pure DPPC dispersion within the investigated temperature range.
基金supported by the Independent Innovation Foundation of Shandong University(No.2009JC004)the Natural Science Foundation of Shandong Province(No.Y2007G31)
文摘A novel algorithm for active noise control systems based on frequency selective filters （FSFANC） is presented in the paper. The FSFANC aims at the multi-tonal noise attenuation problem. One FSFANC system copes with one of the tonal components, and several FSFANC systems can run independently in paralld to cancel the selected multiple tones. The proposed algorithm adopts a simple structure with only two coefficients that can be explained as the real and imaginary parts of the structure to model the secondary path, and estimates the secondary path by injecting sinusoidal identification signals. Theoretical analysis and laboratory experiments show that the proposed algorithm possesses stone advantages, such as simpler structure, less computational burden, greater stability, and fast converging speed.
文摘Objective: To observe the therapeutic effect of the integrated acupuncture-moxibustio n and herbal therapies for facial paralysis. Methods: A total of 68 cases of facial paralysis were treated by integration of acupunct ure-moxibustion and herbal therapies. For acu-moxibustion, Yifeng (翳风 TE 17) , Dicang (地仓 ST 4), Jiache (颊车 ST 6), Yangbai (阳白 GB 14), Hegu (合谷 LI 4), etc. were used. In addition, for facial palsy patients with wind-phlegm blockin g meridian-collaterals and wind-stirring due to yin defi ciency types in the acute stage, Modified Qian Zheng San (牵正散 Powder for Treating Wry-mouth) and Modi f ied Zhen Gan Xi Feng Tang (镇肝熄风汤 Tranquilizing Liver-wind Decoction) were u sed respectively; and for those in convalescent stage and sequela stage, Modifie d Danggui Bu Xue Tang (当归补血汤 Ghinese Angelica Decoction for Replenishing Bl ood) + Qian Zheng San (Powder for Treating Wry-mouth) and Modified Bu Yang Hu an Wu Tang (补阳还五汤 Decoction Invigorating Yang for Recuperation) were employed. Results: After the treatment, the curative rate of the 68 cases a ccounted for 90 % of the total cases, the remarkably effective 6%, the improved 3% and the poor 1% respectively. Conclusion: The therapeutic effectiveness of the integrated tre atment of acupuncture-moxibustion and herbal therapies for facial paralysis is certain.
