Local culture resources were excavated and expressed in environmental landscape section of ‘Miaojiang ·Yujinyuan’ residential plot in Taijiang County of Guizhou Province, with lusheng, Bronze drum and national ...Local culture resources were excavated and expressed in environmental landscape section of ‘Miaojiang ·Yujinyuan’ residential plot in Taijiang County of Guizhou Province, with lusheng, Bronze drum and national architecture as design elements. Making environmental landscape of residential plot, where the minority nationality lived in, possess culture agreement and emotion arrangement.展开更多
As a basic color in human languages,the red color shares the common visual impression.Studying the color term can be traced to different social and cultural features.This article mainly discusses the universality and ...As a basic color in human languages,the red color shares the common visual impression.Studying the color term can be traced to different social and cultural features.This article mainly discusses the universality and individuality of red color in languages,aiming to help the second language learners and the multicultural interlocutors.展开更多
Integrity and disparity are two of the basic characteristics implied in the scientific connotation of the physical environment as a material system. From a dialectical materialistic point of view the physical characte...Integrity and disparity are two of the basic characteristics implied in the scientific connotation of the physical environment as a material system. From a dialectical materialistic point of view the physical character of geographical environment of the earth surface is the unity in diversity. It is on such grounds that the two basic characteristics were put forth by the author in his monograph 'Physical Structure of South American Geographical Environment' as the underlying theme. This holds true for the hierarchy of physical regions. For instance, the physical environment of the earth surface in unity behaves as a huge whole, yet, in differentiation into continents, it displays disparity; each continent differs from others and becomes an integrity in its own right. The same is true of regions of lower levels. In the case of generality and individuality of regional types and their constituent distributive areas in different continents, the same relationship exists among them. Owing to similar origin展开更多
Duetting,or the stereotypical,repeated and often coordinated vocalizations between 2 individuals arose independently multiple times in the Order Primates.Across primate species,there exists substantial variation in te...Duetting,or the stereotypical,repeated and often coordinated vocalizations between 2 individuals arose independently multiple times in the Order Primates.Across primate species,there exists substantial variation in terms of timing,degree of overlap,and sex-specificity of duet contributions.There is increasing evidence that primates can modify the timing of their duet contributions relative to their partner,and this vocal flexibility may have been an important precursor to the evolution of human language.Here,we present the results of a fine-scale analysis of Gursky’s spectral tarsier Tarsius spectrumgurskyae duet phrases recorded in North Sulawesi,Indonesia.Specifically,we aimed to investigate individual-level variation in the female and male contributions to the duet,quantify individual-and pair-level differences in duet timing,and measure temporal precision of duetting individuals relative to their partner.We were able to classify female duet phrases to the correct individual with an 80%accuracy using support vector machines,whereas our classification accuracy for males was lower at 64%.Females were more variable than males in terms of timing between notes.All tarsier phrases exhibited some degree of overlap between callers,and tarsiers exhibited high temporal precision in their note output relative to their partners.We provide evidence that duetting tarsier individuals can modify their note output relative to their duetting partner,and these results support the idea that flexibility in vocal exchanges—a precursor to human language—evolved early in the primate lineage and long before the emergence of modern humans.展开更多
Many species produce individually specific vocalizations and sociality is a hypothesized driver of such individuality. Previous studies of how social variation influenced individuality focused on colonial or non-colon...Many species produce individually specific vocalizations and sociality is a hypothesized driver of such individuality. Previous studies of how social variation influenced individuality focused on colonial or non-colonial avian species, and how so- cial group size influenced individuality in sciurid rodents. Since sociality is an important driver of individuality, we expected that bird species that defend nesting territories in higher density neighborhoods should have more individually-distinctive calls than those that defend nesting territories in lower-density neighborhoods. We used Beecher＇s information statistic to quantify individu- ality, and we examined the relationship between bird density （calculated with point-counts） and vocal individuality on seven spe- cies of passerines. We found non-significant relationships between breeding bird density and vocal individuality whether regres- sions were fitted on species values, or on phylogenetically-independent contrast values. From these results, we infer that while in- dividuality may be explained by social factors, breeding bird density is unlikely to be generally important in driving the evolution of individually-specific vocalizations [Current Zoology 58 （5）： 765-772, 2012].展开更多
Background: Individuality in vocalizations may provide an effective tool for surveying populations of the Common Cuckoo(Cuculus canorus) but there remains few data on which technique to use to identify individuality. ...Background: Individuality in vocalizations may provide an effective tool for surveying populations of the Common Cuckoo(Cuculus canorus) but there remains few data on which technique to use to identify individuality. In this research, we compared the within-and between-individual variation in cuckoo calls using two different analytical methods, and discuss the feasibility of using call individuality to count male cuckoos within a population.Methods: We recorded vocalization from 13 males, and measured 15 spectro-temporal variables for each call. The majority of these call variables(n = 12) have greater variation between individuals than within individual. We first calculated the similarity(Pearson's R) for each paired calls in order to find a threshold that could distinguish calls emitted from the same or different males, and then counted the number of males based on this distinction. Second, we used the more widely accepted technique of discriminant function analysis(DFA) to identify individual male cuckoos, and compared the correct rate of classifying individuals between the two analytical methods.Results: Similarity of paired calls from the same male was significantly higher than from different males. Under a relatively broad threshold interval, we achieved a high(>90%) correct rate to distinguish calls and an accurate estimate of male numbers. Based on banded males(n = 3), we found the similarity of paired calls from different days was lower when compared with paired calls from the same day, but this change did not obscure individual identification, as similarity values of paired calls from different days were still larger than the threshold used to distinguish calls from the same or different males. DFA also yielded a high rate(91.9%) of correct classification of individuals.Conclusions: Our study suggests that identifying individual vocalizations can form the basis of an appropriate survey method for counting male cuckoos within a population, provided the performance of different analytical techniques are compared.展开更多
The theory of linguistic individuality and second language individuality,especially the three-level structure of Y.N.Karaulov,reveals the two most important factors influencing translation,which has great guiding sign...The theory of linguistic individuality and second language individuality,especially the three-level structure of Y.N.Karaulov,reveals the two most important factors influencing translation,which has great guiding significance to translation practice.展开更多
The objective of this study was to clarify the contents of “care that respects individuality” provided to elderly people with dementia living in group homes as perceived by dementia carers qualified. We interviewed ...The objective of this study was to clarify the contents of “care that respects individuality” provided to elderly people with dementia living in group homes as perceived by dementia carers qualified. We interviewed 21 dementia carers qualified working at group homes in Prefecture A about the practical contents of and their thoughts on “care that respects individuality”. The data obtained from the interviews were analyzed using the modified grounded theory approach (M-GTA). As a result, 14 concepts regarding the contents of “care that respects individuality” provided to elderly people with dementia living in group homes as perceived by dementia carers qualified were generated in the following 4 categories: “placing emphasis on the individual”, “respecting feelings”, “eliciting strengths”, and “close mutual relationship”.展开更多
Under the background of binary opposition of modern philosophy and aesthetics, Hegel takes ＂spirit＂ as the startingpoint and aims to achieve the reconciliation between binaries through the dialectical development of...Under the background of binary opposition of modern philosophy and aesthetics, Hegel takes ＂spirit＂ as the startingpoint and aims to achieve the reconciliation between binaries through the dialectical development of spirit. At thesame time, this process also makes spirit reach its own self-consciousness and self-realization. Among manyoppositions and contradictions, one of the key issues that Hegel attempts to deal with is the relationship betweenindividuality and universality in spirit. In Hegel＇s view, spirit is universal self-consciousness, a unity ofindividuality and universality. Consistent with his philosophy, the task of his aesthetics is also to reconcileuniversality and individuality in spirit. In Aesthetics, this settlement is mainly reflected in three aspects, namely theunity of content and form, the unity of the general world situation, and the character and finally the unity ofsubjective artistic creation and objective performance. In this way, Hegel＇s Aesthetics bridges the distance betweenindividuality and universality, achieving the goal of self-consciousness and self-realization in spirit, thus giving hisresponse to the problem of binary opposition caused by modern philosophy and aesthetics.展开更多
The individualized primary school Chinese composition teaching, in terms of its teaching process, teaching objectives, teaching contents, etc., should be based on the students' actual situation and composition per...The individualized primary school Chinese composition teaching, in terms of its teaching process, teaching objectives, teaching contents, etc., should be based on the students' actual situation and composition performance. In this process, teachers should fully reflect the students' subjectivity and teach students in accordance with their aptitude. Only in this way can students be more willing to express their feelings and enthusiasm for life, and thus can a good foundation be laid for the improvement of students' writing ability.展开更多
Quality education reform in China gives high importance to developing the individual's full potential.However,the education system is dominated by a kind of exclusive competitiveness in which high stakes examinati...Quality education reform in China gives high importance to developing the individual's full potential.However,the education system is dominated by a kind of exclusive competitiveness in which high stakes examinations shape the learning process.This paper seeks to bring a philosophical perspective regarding the disjunction between the intent of reform and the reality of an exam-oriented system by proposing a conception of inclusive individuality.I argue that the conception of inclusive individuality pays particular attention to the inner strength of every unique student and is crucial to realizing the individual's full potential.The ideas of three philosophers,John Dewey,Liang Shuming,and Albert Camus,are drawn upon in formulating this conception of inclusive individuality.At the practical level,the paper suggests the use of narrative approach as a way of developing students'inner strength to bring their lives into the classroom and empowering them to interact with the formal curriculum and develop their own inclusive individuality.展开更多
This article identifies the problem that an instrumentalist mode of thinking dominates China’s contemporary education practice and suggests that the dichotomy between the“small self and big self,”a notion that has ...This article identifies the problem that an instrumentalist mode of thinking dominates China’s contemporary education practice and suggests that the dichotomy between the“small self and big self,”a notion that has been present throughout modern Chinese history,exacerbates this instrumentalism.It parallels the loss of China’s tradition of self-cultivation in the modern education system.This paper proposes that cultivating the inner self by releasing talent unique to each individual as well as energy for creatively making meaningful connections with others may represent a new means of moving past the dichotomy of the“small self and big self.”The paper examines this issue through a comparative analysis of Hu Shi and Liang Shuming’s thoughts on individuality.展开更多
This paper explores,through the lens of childhood,the Chinese cultural dynamics that encourage harmonious human relationships at the price of individual development and yet support a deep appreciation of natural human...This paper explores,through the lens of childhood,the Chinese cultural dynamics that encourage harmonious human relationships at the price of individual development and yet support a deep appreciation of natural human experiences that allows room for the development of individuality.The purpose of such investigation is to reexamine our cultural heritage in regard to the ways we conceptualize human beings and treat them,retracing its promises,difficulties,pitfalls,and spiritual resources,and thus to help reconfigure a new individuality for education.展开更多
BACKGROUND Perioperative anesthesia management of obese patients presents significant challenges as traditional total body weight-based dosing fails to achieve optimal anesthetic effects due to altered pharmacokinetic...BACKGROUND Perioperative anesthesia management of obese patients presents significant challenges as traditional total body weight-based dosing fails to achieve optimal anesthetic effects due to altered pharmacokinetic characteristics including abnormal drug distribution and clearance.Rocuronium exhibits markedly different distribution patterns in obese patients,with conventional weight correction methods inadequately addressing individual muscle mass variations that critically influence drug distribution.AIM To investigate the quantitative relationship between skeletal muscle index(SMI)and rocuronium distribution volume in obese colorectal cancer patients,establish a population pharmacokinetic model,and develop individualized dosing strategies based on muscle mass.METHODS A retrospective cohort study was conducted,including 100 obese patients(body mass index≥30 kg/m^(2))who underwent elective radical colorectal cancer surgery at our hospital from June 2023 to January 2025.Skeletal muscle mass was measured using InBody 260 body composition analyzer and SMI was calculated to assess muscle mass,with male SMI<7.0 kg/m^(2) and female SMI<5.7 kg/m^(2)as diagnostic criteria for sarcopenia.Plasma rocuronium concentrations were detected by liquid chromatography-tandem mass spectrometry/mass spectrometry,and nonlinear mixed-effect modeling was used to establish population pharmacokinetic modeling.Stepwise regression was used to screen covariates,and dosing regimens were optimized through Monte Carlo simulation.The primary endpoint was targeted plasma concentration achievement rate,and the secondary endpoint was postoperative residual muscle relaxation incidence.RESULTS Among 100 patients,35(35.0%)had sarcopenia and 65(65.0%)did not.Patients in the sarcopenia group were older(64.1±9.8 years vs 54.2±10.9 years,P<0.001)and had significantly lower SMI(6.2±0.8 kg/m^(2)vs 8.4±1.2 kg/m^(2),P<0.001).SMI showed strong positive correlation with rocuronium steady-state distribution volume(r=0.718,P<0.001)and moderate negative correlation with clearance(r=-0.502,P<0.001).A two-compartment population pharmacokinetic model was successfully established,with SMI being the most important covariate affecting central compartment distribution volume(△OFV=-41.2,P<0.001).Model validation showed bootstrap successful convergence rate of 92.3%,and 92.1%of observed values fell within prediction intervals in predicted concentration versus predicted concentration.The SMI-based individualized dosing regimen improved target exposure achievement rate from 82.0%in traditional regimen to 93.5%(P=0.009),and reduced postoperative residual muscle relaxation incidence from 13.0%to 3.5%(P=0.018).The sarcopenia group showed the most significant improvement in achievement rate,from 71.4%to 93.8%(P=0.017).CONCLUSION SMI shows strong correlation with rocuronium distribution volume in obese colorectal cancer patients and is a key factor affecting drug distribution.SMI-based individualized dosing strategies can significantly improve target exposure achievement rate and reduce postoperative residual muscle relaxation incidence,providing scientific evidence for precision anesthesia management in obese patients.展开更多
Gastrointestinal tumors require personalized treatment strategies due to their heterogeneity and complexity.Multimodal artificial intelligence(AI)addresses this challenge by integrating diverse data sources-including ...Gastrointestinal tumors require personalized treatment strategies due to their heterogeneity and complexity.Multimodal artificial intelligence(AI)addresses this challenge by integrating diverse data sources-including computed tomography(CT),magnetic resonance imaging(MRI),endoscopic imaging,and genomic profiles-to enable intelligent decision-making for individualized therapy.This approach leverages AI algorithms to fuse imaging,endoscopic,and omics data,facilitating comprehensive characterization of tumor biology,prediction of treatment response,and optimization of therapeutic strategies.By combining CT and MRI for structural assessment,endoscopic data for real-time visual inspection,and genomic information for molecular profiling,multimodal AI enhances the accuracy of patient stratification and treatment personalization.The clinical implementation of this technology demonstrates potential for improving patient outcomes,advancing precision oncology,and supporting individualized care in gastrointestinal cancers.Ultimately,multimodal AI serves as a transformative tool in oncology,bridging data integration with clinical application to effectively tailor therapies.展开更多
The inability to access brain tissue has greatly hindered our ability to study and care for individuals suffering from psychiatric and neurological conditions.Critics have questioned efforts to develop peripheral bloo...The inability to access brain tissue has greatly hindered our ability to study and care for individuals suffering from psychiatric and neurological conditions.Critics have questioned efforts to develop peripheral blood biomarkers in neurological and psychiatric disorders based on the assertion that disease pathology is limited to the brain.The discovery that all tissues,including the brain,release extracellular vesicles(Raposo and Stoorvogel,2013)and cell free DNAs(Chan et al.,2013)into various body fluids has provided a potential way to measure activity from inaccessible tissues like the central nervous system(CNS)and has given rise to the term“liquid biopsy.”The development of liquid biopsies that can diagnose and predict the course of psychiatric and neurological disorders would be transformative.The ability to predict episodic events such as mania,depression,and risk for suicide would be particularly useful for psychiatric care as it would enable the development of interventions that prevent mortality and improve outcomes.Additionally,biomarkers that are informative about drug response and aid in treatment decisions would be a significant advance in psychiatric care as it would prevent patients from having to endure multiple courses of ineffective treatments and side effects.展开更多
Vocal individuality is essential for social discrimination but has been poorly studied in animals that produce communal signals(duets or choruses).Song overlapping and temporal coordination make the assessment of indi...Vocal individuality is essential for social discrimination but has been poorly studied in animals that produce communal signals(duets or choruses).Song overlapping and temporal coordination make the assessment of individuality in communal signals more complex.In addition,selection may favor the accurate identifcation of pairs over individuals by receivers in year-round territorial species with duetting and long-term pair bonding.Here,we studied pair and individual vocal signatures in the polyphonal duets of rufous horneros Furnarius rufus,a Neotropical bird known for its long-term pair bonds.Hornero partners engage in duets to deter territorial intruders and protect their partnership year-round and can discern duets from neighbors versus strangers.Using a dataset of 471 duets from 43 pairs in 2 populations,we measured fne-scale acoustic features across different duet levels(e.g.,complete duets to non-overlapping syllable parts)and analysis levels(pair or individual).Permuted linear discriminant function analyses classifed pairs and individuals more accurately than expected by chance(means:45%and 47%vs.4 and 2%).Pair identity explained more variance in the multivariate acoustic features of duets than individual or population identities.The initial frequency of the duet showed strong potential for encoding pair identity.The acoustic traits contributing most to individual vocal signatures varied between sexes,which might facilitate the simultaneous assessment of duetters’identities by receivers.Our study indicates that vocal individuality may exist even in species with intricate and innate communal signals and elucidates the mechanisms employed by horneros in their social discrimination ability.展开更多
Animals can differ in their individual movement behaviors during their daily displacements.Studies of animal movement patterns often disregard the need to understand individual variation in these patterns and the role...Animals can differ in their individual movement behaviors during their daily displacements.Studies of animal movement patterns often disregard the need to understand individual variation in these patterns and the role of this variation in shaping population distributions of movements.To assess the link between individual movements and population distributions,we radio-tracked 13 Fowler's Toads Anaxyrus fowleri in Long Point,Ontario,Canada,after their breeding season.We recorded individual coordinates every 30 min,from the moment they emerged from their burrows around dusk until they burrowed in the morning,and obtained a total of 157 movements.We used the resulting series of step lengths and turning angles in a Hidden Markov Model to estimate movement type as"directed"or"non-directed"We also assigned to each encounter one of 3 space-dependent movement states:"foraging""in transit'or"searching"and found that movement type and state switched within individuals irrespective of time during a single night.We find that switching between movement types varied throughout the night,leading to stochastic within-individual variation in movements,and the distribution of movement distances differed significantly among individuals.Movement states,however,were time-dependent,suggesting displacement routines were similar across individuals.Variation in movement behavior within individuals scales up to result in variation among individuals which,in turn,was found to shape the distribution of the sampled population.Our findings therefore underline the importance of a multi-scale approach in the study of movement.展开更多
BACKGROUND Hepatocellular carcinoma ranks among the most prevalent malignant neoplasms.Surgical intervention constitutes a critical therapeutic approach for this condition.Nonetheless,postoperative recovery is frequen...BACKGROUND Hepatocellular carcinoma ranks among the most prevalent malignant neoplasms.Surgical intervention constitutes a critical therapeutic approach for this condition.Nonetheless,postoperative recovery is frequently influenced by the patient's nutritional status and the quality of nursing care provided.AIM To examine the comprehensive impact of personalized nutritional support and nursing strategies on the postoperative rehabilitation of patients with liver cancer.METHODS In this study,a retrospective comparative analysis was conducted involving 60 post-operative liver cancer patients.The subjects were selected as subjects and divided into two groups based on differing nursing interventions,with each group comprising 30 patients.The control group received standard nutritional support and care,whereas the experimental group received individualized nutritional support and nursing strategies.The study aimed to evaluate the impact of individualized nutrition by comparing the rehabilitation indices,nutritional status,quality of life(QoL),and complication rates between the two groups.RESULTS The results showed that the recovery index of the experimental group was significantly better than that of the control group 2 weeks after surgery,and the average liver function recovery index of the experimental group was 85.significantly higher than that of the control group(73.67±7.19).In terms of nutritional status,the serum albumin level and body weight stabilization rate of the experimental group were also significantly higher than those of the control group,which were 42.33±2.4 g/L and 93.3%,respectively,compared with 36.01±3.85 g/L and 76.7%of the control group.In addition,the average QoL score of the experimental group was 84.66±3.7 points,which was significantly higher than that of the control group(70.92±4.28 points).At the psychological level,the average anxiety score of the experimental group was 1.17±0.29,and the average depression score was 1.47±0.4,which were significantly lower than the 2.26±0.42 and 2.57±0.45 of the control group.This showed that patients in the experimental group were better relieved of anxiety and depression under the individualized nutrition support and nursing strategy.More importantly,the complication rate in the experimental group was only 10%,much lower than the 33.3%in the control group.CONCLUSION Personalized nutritional support and tailored nursing strategies significantly enhance the postoperative rehabilitation of liver cancer patients.Consequently,it is recommended to implement and advocate for these individualized approaches to improve both the recovery outcomes and QoL for these patients.展开更多
We identify an S-shaped main-jet axis in the Vela core-collapse supernova remnant(CCSNR)that we attribute to a pair of precessing jets,one of the tens of pairs of jets that exploded the progenitor of Vela according to...We identify an S-shaped main-jet axis in the Vela core-collapse supernova remnant(CCSNR)that we attribute to a pair of precessing jets,one of the tens of pairs of jets that exploded the progenitor of Vela according to the jittering jets explosion mechanism(JJEM).A main-jet axis is a symmetry axis across the CCSNR and through the center.We identify the S-shaped main-jet axis by the high abundance of ejecta elements,oxygen,neon,and magnesium.We bring the number of identified pairs of clumps and ears in Vela to seven,two pairs shaped by the pair of precessing jets that formed the main-jet axis.The pairs and the main-jet axis form the point-symmetric wind-rose structure of Vela.The other five pairs of clumps/ears do not have signatures near the center,only on two opposite sides of the CCSNR.We discuss different possible jet-less shaping mechanisms to form such a point-symmetric morphology and dismiss these processes because they cannot explain the point-symmetric morphology of Vela,the S-shaped high ejecta abundance pattern,and the enormous energy required to shape the S-shaped structure.Our findings strongly support the JJEM and further severely challenge the neutrino-driven explosion mechanism.展开更多
文摘Local culture resources were excavated and expressed in environmental landscape section of ‘Miaojiang ·Yujinyuan’ residential plot in Taijiang County of Guizhou Province, with lusheng, Bronze drum and national architecture as design elements. Making environmental landscape of residential plot, where the minority nationality lived in, possess culture agreement and emotion arrangement.
文摘As a basic color in human languages,the red color shares the common visual impression.Studying the color term can be traced to different social and cultural features.This article mainly discusses the universality and individuality of red color in languages,aiming to help the second language learners and the multicultural interlocutors.
文摘Integrity and disparity are two of the basic characteristics implied in the scientific connotation of the physical environment as a material system. From a dialectical materialistic point of view the physical character of geographical environment of the earth surface is the unity in diversity. It is on such grounds that the two basic characteristics were put forth by the author in his monograph 'Physical Structure of South American Geographical Environment' as the underlying theme. This holds true for the hierarchy of physical regions. For instance, the physical environment of the earth surface in unity behaves as a huge whole, yet, in differentiation into continents, it displays disparity; each continent differs from others and becomes an integrity in its own right. The same is true of regions of lower levels. In the case of generality and individuality of regional types and their constituent distributive areas in different continents, the same relationship exists among them. Owing to similar origin
基金Funding for this research was provided by a Fulbright ASEAN Research Award for U.S.Scholars(no award number given).
文摘Duetting,or the stereotypical,repeated and often coordinated vocalizations between 2 individuals arose independently multiple times in the Order Primates.Across primate species,there exists substantial variation in terms of timing,degree of overlap,and sex-specificity of duet contributions.There is increasing evidence that primates can modify the timing of their duet contributions relative to their partner,and this vocal flexibility may have been an important precursor to the evolution of human language.Here,we present the results of a fine-scale analysis of Gursky’s spectral tarsier Tarsius spectrumgurskyae duet phrases recorded in North Sulawesi,Indonesia.Specifically,we aimed to investigate individual-level variation in the female and male contributions to the duet,quantify individual-and pair-level differences in duet timing,and measure temporal precision of duetting individuals relative to their partner.We were able to classify female duet phrases to the correct individual with an 80%accuracy using support vector machines,whereas our classification accuracy for males was lower at 64%.Females were more variable than males in terms of timing between notes.All tarsier phrases exhibited some degree of overlap between callers,and tarsiers exhibited high temporal precision in their note output relative to their partners.We provide evidence that duetting tarsier individuals can modify their note output relative to their duetting partner,and these results support the idea that flexibility in vocal exchanges—a precursor to human language—evolved early in the primate lineage and long before the emergence of modern humans.
文摘Many species produce individually specific vocalizations and sociality is a hypothesized driver of such individuality. Previous studies of how social variation influenced individuality focused on colonial or non-colonial avian species, and how so- cial group size influenced individuality in sciurid rodents. Since sociality is an important driver of individuality, we expected that bird species that defend nesting territories in higher density neighborhoods should have more individually-distinctive calls than those that defend nesting territories in lower-density neighborhoods. We used Beecher＇s information statistic to quantify individu- ality, and we examined the relationship between bird density （calculated with point-counts） and vocal individuality on seven spe- cies of passerines. We found non-significant relationships between breeding bird density and vocal individuality whether regres- sions were fitted on species values, or on phylogenetically-independent contrast values. From these results, we infer that while in- dividuality may be explained by social factors, breeding bird density is unlikely to be generally important in driving the evolution of individually-specific vocalizations [Current Zoology 58 （5）： 765-772, 2012].
基金supported by the Youth Scholars Program of Beijing Normal University (No. 31601868 to CX)National Natural Science Foundation of China (No. 31301888 to DL)+1 种基金General scientific research project of Education Department of Liaoning Province (L2015196 to DL)Open Fund of Ministry of Education Key Laboratory for Biodiversity Sciences and Ecological Engineering, Beijing Normal University (K1401 to DL)
文摘Background: Individuality in vocalizations may provide an effective tool for surveying populations of the Common Cuckoo(Cuculus canorus) but there remains few data on which technique to use to identify individuality. In this research, we compared the within-and between-individual variation in cuckoo calls using two different analytical methods, and discuss the feasibility of using call individuality to count male cuckoos within a population.Methods: We recorded vocalization from 13 males, and measured 15 spectro-temporal variables for each call. The majority of these call variables(n = 12) have greater variation between individuals than within individual. We first calculated the similarity(Pearson's R) for each paired calls in order to find a threshold that could distinguish calls emitted from the same or different males, and then counted the number of males based on this distinction. Second, we used the more widely accepted technique of discriminant function analysis(DFA) to identify individual male cuckoos, and compared the correct rate of classifying individuals between the two analytical methods.Results: Similarity of paired calls from the same male was significantly higher than from different males. Under a relatively broad threshold interval, we achieved a high(>90%) correct rate to distinguish calls and an accurate estimate of male numbers. Based on banded males(n = 3), we found the similarity of paired calls from different days was lower when compared with paired calls from the same day, but this change did not obscure individual identification, as similarity values of paired calls from different days were still larger than the threshold used to distinguish calls from the same or different males. DFA also yielded a high rate(91.9%) of correct classification of individuals.Conclusions: Our study suggests that identifying individual vocalizations can form the basis of an appropriate survey method for counting male cuckoos within a population, provided the performance of different analytical techniques are compared.
文摘The theory of linguistic individuality and second language individuality,especially the three-level structure of Y.N.Karaulov,reveals the two most important factors influencing translation,which has great guiding significance to translation practice.
文摘The objective of this study was to clarify the contents of “care that respects individuality” provided to elderly people with dementia living in group homes as perceived by dementia carers qualified. We interviewed 21 dementia carers qualified working at group homes in Prefecture A about the practical contents of and their thoughts on “care that respects individuality”. The data obtained from the interviews were analyzed using the modified grounded theory approach (M-GTA). As a result, 14 concepts regarding the contents of “care that respects individuality” provided to elderly people with dementia living in group homes as perceived by dementia carers qualified were generated in the following 4 categories: “placing emphasis on the individual”, “respecting feelings”, “eliciting strengths”, and “close mutual relationship”.
文摘Under the background of binary opposition of modern philosophy and aesthetics, Hegel takes ＂spirit＂ as the startingpoint and aims to achieve the reconciliation between binaries through the dialectical development of spirit. At thesame time, this process also makes spirit reach its own self-consciousness and self-realization. Among manyoppositions and contradictions, one of the key issues that Hegel attempts to deal with is the relationship betweenindividuality and universality in spirit. In Hegel＇s view, spirit is universal self-consciousness, a unity ofindividuality and universality. Consistent with his philosophy, the task of his aesthetics is also to reconcileuniversality and individuality in spirit. In Aesthetics, this settlement is mainly reflected in three aspects, namely theunity of content and form, the unity of the general world situation, and the character and finally the unity ofsubjective artistic creation and objective performance. In this way, Hegel＇s Aesthetics bridges the distance betweenindividuality and universality, achieving the goal of self-consciousness and self-realization in spirit, thus giving hisresponse to the problem of binary opposition caused by modern philosophy and aesthetics.
文摘The individualized primary school Chinese composition teaching, in terms of its teaching process, teaching objectives, teaching contents, etc., should be based on the students' actual situation and composition performance. In this process, teachers should fully reflect the students' subjectivity and teach students in accordance with their aptitude. Only in this way can students be more willing to express their feelings and enthusiasm for life, and thus can a good foundation be laid for the improvement of students' writing ability.
文摘Quality education reform in China gives high importance to developing the individual's full potential.However,the education system is dominated by a kind of exclusive competitiveness in which high stakes examinations shape the learning process.This paper seeks to bring a philosophical perspective regarding the disjunction between the intent of reform and the reality of an exam-oriented system by proposing a conception of inclusive individuality.I argue that the conception of inclusive individuality pays particular attention to the inner strength of every unique student and is crucial to realizing the individual's full potential.The ideas of three philosophers,John Dewey,Liang Shuming,and Albert Camus,are drawn upon in formulating this conception of inclusive individuality.At the practical level,the paper suggests the use of narrative approach as a way of developing students'inner strength to bring their lives into the classroom and empowering them to interact with the formal curriculum and develop their own inclusive individuality.
文摘This article identifies the problem that an instrumentalist mode of thinking dominates China’s contemporary education practice and suggests that the dichotomy between the“small self and big self,”a notion that has been present throughout modern Chinese history,exacerbates this instrumentalism.It parallels the loss of China’s tradition of self-cultivation in the modern education system.This paper proposes that cultivating the inner self by releasing talent unique to each individual as well as energy for creatively making meaningful connections with others may represent a new means of moving past the dichotomy of the“small self and big self.”The paper examines this issue through a comparative analysis of Hu Shi and Liang Shuming’s thoughts on individuality.
文摘This paper explores,through the lens of childhood,the Chinese cultural dynamics that encourage harmonious human relationships at the price of individual development and yet support a deep appreciation of natural human experiences that allows room for the development of individuality.The purpose of such investigation is to reexamine our cultural heritage in regard to the ways we conceptualize human beings and treat them,retracing its promises,difficulties,pitfalls,and spiritual resources,and thus to help reconfigure a new individuality for education.
文摘BACKGROUND Perioperative anesthesia management of obese patients presents significant challenges as traditional total body weight-based dosing fails to achieve optimal anesthetic effects due to altered pharmacokinetic characteristics including abnormal drug distribution and clearance.Rocuronium exhibits markedly different distribution patterns in obese patients,with conventional weight correction methods inadequately addressing individual muscle mass variations that critically influence drug distribution.AIM To investigate the quantitative relationship between skeletal muscle index(SMI)and rocuronium distribution volume in obese colorectal cancer patients,establish a population pharmacokinetic model,and develop individualized dosing strategies based on muscle mass.METHODS A retrospective cohort study was conducted,including 100 obese patients(body mass index≥30 kg/m^(2))who underwent elective radical colorectal cancer surgery at our hospital from June 2023 to January 2025.Skeletal muscle mass was measured using InBody 260 body composition analyzer and SMI was calculated to assess muscle mass,with male SMI<7.0 kg/m^(2) and female SMI<5.7 kg/m^(2)as diagnostic criteria for sarcopenia.Plasma rocuronium concentrations were detected by liquid chromatography-tandem mass spectrometry/mass spectrometry,and nonlinear mixed-effect modeling was used to establish population pharmacokinetic modeling.Stepwise regression was used to screen covariates,and dosing regimens were optimized through Monte Carlo simulation.The primary endpoint was targeted plasma concentration achievement rate,and the secondary endpoint was postoperative residual muscle relaxation incidence.RESULTS Among 100 patients,35(35.0%)had sarcopenia and 65(65.0%)did not.Patients in the sarcopenia group were older(64.1±9.8 years vs 54.2±10.9 years,P<0.001)and had significantly lower SMI(6.2±0.8 kg/m^(2)vs 8.4±1.2 kg/m^(2),P<0.001).SMI showed strong positive correlation with rocuronium steady-state distribution volume(r=0.718,P<0.001)and moderate negative correlation with clearance(r=-0.502,P<0.001).A two-compartment population pharmacokinetic model was successfully established,with SMI being the most important covariate affecting central compartment distribution volume(△OFV=-41.2,P<0.001).Model validation showed bootstrap successful convergence rate of 92.3%,and 92.1%of observed values fell within prediction intervals in predicted concentration versus predicted concentration.The SMI-based individualized dosing regimen improved target exposure achievement rate from 82.0%in traditional regimen to 93.5%(P=0.009),and reduced postoperative residual muscle relaxation incidence from 13.0%to 3.5%(P=0.018).The sarcopenia group showed the most significant improvement in achievement rate,from 71.4%to 93.8%(P=0.017).CONCLUSION SMI shows strong correlation with rocuronium distribution volume in obese colorectal cancer patients and is a key factor affecting drug distribution.SMI-based individualized dosing strategies can significantly improve target exposure achievement rate and reduce postoperative residual muscle relaxation incidence,providing scientific evidence for precision anesthesia management in obese patients.
基金Supported by Xuhui District Health Commission,No.SHXH202214.
文摘Gastrointestinal tumors require personalized treatment strategies due to their heterogeneity and complexity.Multimodal artificial intelligence(AI)addresses this challenge by integrating diverse data sources-including computed tomography(CT),magnetic resonance imaging(MRI),endoscopic imaging,and genomic profiles-to enable intelligent decision-making for individualized therapy.This approach leverages AI algorithms to fuse imaging,endoscopic,and omics data,facilitating comprehensive characterization of tumor biology,prediction of treatment response,and optimization of therapeutic strategies.By combining CT and MRI for structural assessment,endoscopic data for real-time visual inspection,and genomic information for molecular profiling,multimodal AI enhances the accuracy of patient stratification and treatment personalization.The clinical implementation of this technology demonstrates potential for improving patient outcomes,advancing precision oncology,and supporting individualized care in gastrointestinal cancers.Ultimately,multimodal AI serves as a transformative tool in oncology,bridging data integration with clinical application to effectively tailor therapies.
基金supported by Department of Defense grant HT9425-24-1-0030 a grant from the Stanley Medical Research Institute(to SS).
文摘The inability to access brain tissue has greatly hindered our ability to study and care for individuals suffering from psychiatric and neurological conditions.Critics have questioned efforts to develop peripheral blood biomarkers in neurological and psychiatric disorders based on the assertion that disease pathology is limited to the brain.The discovery that all tissues,including the brain,release extracellular vesicles(Raposo and Stoorvogel,2013)and cell free DNAs(Chan et al.,2013)into various body fluids has provided a potential way to measure activity from inaccessible tissues like the central nervous system(CNS)and has given rise to the term“liquid biopsy.”The development of liquid biopsies that can diagnose and predict the course of psychiatric and neurological disorders would be transformative.The ability to predict episodic events such as mania,depression,and risk for suicide would be particularly useful for psychiatric care as it would enable the development of interventions that prevent mortality and improve outcomes.Additionally,biomarkers that are informative about drug response and aid in treatment decisions would be a significant advance in psychiatric care as it would prevent patients from having to endure multiple courses of ineffective treatments and side effects.
基金P.D.and P.S.A.received Ph.D.scholarships from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior(CAPES)(Finance Code 001)P.D.received a Postdoctoral fellowship from CAPES(grant number:88887.469218/2019-00)+4 种基金R.H.M.received a fellowship from Conselho Nacional de Desenvolvimento Científco e Tecnológico(CNPq)for the duration of the study.Funding was also provided by Animal Behavior Society[ABS Student Research Grant to P.S.A.]Association of Field Ornithologists[E.Alexander Bergstrom Memorial Research Award to P.S.A.]American Ornithological Society[Postdoctoral Research Award to P.D.]the logistic and fnancial support provided by Programa de Pós-Graduação em Ecologia from Universidade de Brasília in association with Programa de Excelência Acadêmica PROEX/CAPES(1789/2015)the fnancial support provided by CNPq(471945/2013-7).
文摘Vocal individuality is essential for social discrimination but has been poorly studied in animals that produce communal signals(duets or choruses).Song overlapping and temporal coordination make the assessment of individuality in communal signals more complex.In addition,selection may favor the accurate identifcation of pairs over individuals by receivers in year-round territorial species with duetting and long-term pair bonding.Here,we studied pair and individual vocal signatures in the polyphonal duets of rufous horneros Furnarius rufus,a Neotropical bird known for its long-term pair bonds.Hornero partners engage in duets to deter territorial intruders and protect their partnership year-round and can discern duets from neighbors versus strangers.Using a dataset of 471 duets from 43 pairs in 2 populations,we measured fne-scale acoustic features across different duet levels(e.g.,complete duets to non-overlapping syllable parts)and analysis levels(pair or individual).Permuted linear discriminant function analyses classifed pairs and individuals more accurately than expected by chance(means:45%and 47%vs.4 and 2%).Pair identity explained more variance in the multivariate acoustic features of duets than individual or population identities.The initial frequency of the duet showed strong potential for encoding pair identity.The acoustic traits contributing most to individual vocal signatures varied between sexes,which might facilitate the simultaneous assessment of duetters’identities by receivers.Our study indicates that vocal individuality may exist even in species with intricate and innate communal signals and elucidates the mechanisms employed by horneros in their social discrimination ability.
基金funded by grants from the Fonds de Recherche du Quebec-Nature et Technologies(FRQNT)to NJthe Ontario Ministry of Natural Resources and Forestrythe Ontario Ministry of Environment,Conservation and Parks,and the Natural Sciences and Engineering Research Council(NSERC)of Canada to DMG.
文摘Animals can differ in their individual movement behaviors during their daily displacements.Studies of animal movement patterns often disregard the need to understand individual variation in these patterns and the role of this variation in shaping population distributions of movements.To assess the link between individual movements and population distributions,we radio-tracked 13 Fowler's Toads Anaxyrus fowleri in Long Point,Ontario,Canada,after their breeding season.We recorded individual coordinates every 30 min,from the moment they emerged from their burrows around dusk until they burrowed in the morning,and obtained a total of 157 movements.We used the resulting series of step lengths and turning angles in a Hidden Markov Model to estimate movement type as"directed"or"non-directed"We also assigned to each encounter one of 3 space-dependent movement states:"foraging""in transit'or"searching"and found that movement type and state switched within individuals irrespective of time during a single night.We find that switching between movement types varied throughout the night,leading to stochastic within-individual variation in movements,and the distribution of movement distances differed significantly among individuals.Movement states,however,were time-dependent,suggesting displacement routines were similar across individuals.Variation in movement behavior within individuals scales up to result in variation among individuals which,in turn,was found to shape the distribution of the sampled population.Our findings therefore underline the importance of a multi-scale approach in the study of movement.
文摘BACKGROUND Hepatocellular carcinoma ranks among the most prevalent malignant neoplasms.Surgical intervention constitutes a critical therapeutic approach for this condition.Nonetheless,postoperative recovery is frequently influenced by the patient's nutritional status and the quality of nursing care provided.AIM To examine the comprehensive impact of personalized nutritional support and nursing strategies on the postoperative rehabilitation of patients with liver cancer.METHODS In this study,a retrospective comparative analysis was conducted involving 60 post-operative liver cancer patients.The subjects were selected as subjects and divided into two groups based on differing nursing interventions,with each group comprising 30 patients.The control group received standard nutritional support and care,whereas the experimental group received individualized nutritional support and nursing strategies.The study aimed to evaluate the impact of individualized nutrition by comparing the rehabilitation indices,nutritional status,quality of life(QoL),and complication rates between the two groups.RESULTS The results showed that the recovery index of the experimental group was significantly better than that of the control group 2 weeks after surgery,and the average liver function recovery index of the experimental group was 85.significantly higher than that of the control group(73.67±7.19).In terms of nutritional status,the serum albumin level and body weight stabilization rate of the experimental group were also significantly higher than those of the control group,which were 42.33±2.4 g/L and 93.3%,respectively,compared with 36.01±3.85 g/L and 76.7%of the control group.In addition,the average QoL score of the experimental group was 84.66±3.7 points,which was significantly higher than that of the control group(70.92±4.28 points).At the psychological level,the average anxiety score of the experimental group was 1.17±0.29,and the average depression score was 1.47±0.4,which were significantly lower than the 2.26±0.42 and 2.57±0.45 of the control group.This showed that patients in the experimental group were better relieved of anxiety and depression under the individualized nutrition support and nursing strategy.More importantly,the complication rate in the experimental group was only 10%,much lower than the 33.3%in the control group.CONCLUSION Personalized nutritional support and tailored nursing strategies significantly enhance the postoperative rehabilitation of liver cancer patients.Consequently,it is recommended to implement and advocate for these individualized approaches to improve both the recovery outcomes and QoL for these patients.
基金A grant from the Pazy Foundation supported this research
文摘We identify an S-shaped main-jet axis in the Vela core-collapse supernova remnant(CCSNR)that we attribute to a pair of precessing jets,one of the tens of pairs of jets that exploded the progenitor of Vela according to the jittering jets explosion mechanism(JJEM).A main-jet axis is a symmetry axis across the CCSNR and through the center.We identify the S-shaped main-jet axis by the high abundance of ejecta elements,oxygen,neon,and magnesium.We bring the number of identified pairs of clumps and ears in Vela to seven,two pairs shaped by the pair of precessing jets that formed the main-jet axis.The pairs and the main-jet axis form the point-symmetric wind-rose structure of Vela.The other five pairs of clumps/ears do not have signatures near the center,only on two opposite sides of the CCSNR.We discuss different possible jet-less shaping mechanisms to form such a point-symmetric morphology and dismiss these processes because they cannot explain the point-symmetric morphology of Vela,the S-shaped high ejecta abundance pattern,and the enormous energy required to shape the S-shaped structure.Our findings strongly support the JJEM and further severely challenge the neutrino-driven explosion mechanism.
