The atom-bond sum-connectivity(ABS)index,put forward by[J.Math.Chem.,2022,60(10):20812093],exhibits a strong link with the acentric factor of octane isomers.The experimental physico-chemical properties of octane isome...The atom-bond sum-connectivity(ABS)index,put forward by[J.Math.Chem.,2022,60(10):20812093],exhibits a strong link with the acentric factor of octane isomers.The experimental physico-chemical properties of octane isomers,such as boiling point,of formation are found to be better measured by the ABS index than by the Randi,atom-bond connectivity(ABC),and sum-connectivity(SC)indices.One important source of information for researching the molecular structure is the bounds for its topological indices.The extrema of the ABS index of the line,total,and Mycielski graphs are calculated in this work.Moreover,the pertinent extremal graphs were illustrated.展开更多
The Gabes aquifer system,located in southeastern Tunisia,is a crucial resource for supporting local socio-economic activities.Due to its dual porosity structure,is particularly vulnerable to pollution.This study aims ...The Gabes aquifer system,located in southeastern Tunisia,is a crucial resource for supporting local socio-economic activities.Due to its dual porosity structure,is particularly vulnerable to pollution.This study aims to develop a hybrid model that combines the Fracture Aquifer Index(FAI)with the conventional GOD(Groundwater occurrence,Overall lithology,Depth to water table)method,to assess groundwater vulnerability in fractured aquifer.To develop the hybrid model,the classical GOD method was integrated with FAI to produce a single composite index.Each parameter within both GOD and FAI was scored,and a final index was calculated to delineate vulnerable areas.The results show that the study area can be classified into four vulnerability levels:Very low,low,moderate,and high,indicating that approximately 8%of the area exhibits very low vulnerability,29%has low vulnerability,25%falls into the moderate category,and 38%is considered highly vulnerable.The FAI-GOD model further incorporates fracture network characteristics.This refinement reduces the classification to three vulnerability classes:Low,medium,and high.The outcomes demonstrate that 46%of the area is highly vulnerable due to a dense concentration of fractures,while 17%represents an intermediate zone characterized by either shallow or deeper fractures.In contrast,37%corresponds to areas with lightly fractured rock,where the impact on vulnerability is minimal.Multivariate statistical analysis was employed using Principal Components Analysis(PCA)and Hierarchical Cluster Analysis(HCA)on 24 samples across six variables.The first three components account for over 76%of the total variance,reinforcing the significance of fracture dynamics in classifying vulnerability levels.The FAI-GOD model removes the very-low-vulnerability class and expands the spatial extent of low-and high-vulnerability zones,reflecting the dominant influence of fracture networks on aquifer sensitivity.While both indices use a five-class system,FAI-GOD redistributes vulnerability by eliminating very-low-vulnerability areas and amplifying low/high categories,highlighting the critical role of fractures.A strong correlation(R2=0.94)between the GOD and FAI-GOD indices,demonstrated through second-order polynomial regression,confirms the robustness of the FAI-GOD model in accurately predicting vulnerability to pollution.This model provides a useful framework for assessing the vulnerability of complex aquifers and serves as a decision-making tool for groundwater managers in similar areas.展开更多
[Objectives]To analyze the current status of heavy metal contamination in soils of vegetable cultivation bases located in Huichuan District,Zunyi City.[Methods]Soil samples from various depths within the vegetable cul...[Objectives]To analyze the current status of heavy metal contamination in soils of vegetable cultivation bases located in Huichuan District,Zunyi City.[Methods]Soil samples from various depths within the vegetable cultivation bases of Guanba Village,Sidu Village,and Banqiao Village in Huichuan District,Zunyi City,were selected as the subjects of this study.The concentrations of five heavy metals,including lead(Pb),mercury(Hg),cadmium(Cd),arsenic(As),and chromium(Cr),were measured at different soil depths.The Nemerow comprehensive pollution index method was employed to assess heavy metal contamination,and the analysis was conducted in accordance with the farmland environmental quality evaluation standards for edible agricultural products.[Results]The concentrations of Cd and As at the sample collection sites were relatively elevated.The pollution level of Cd reached grade III or above,indicating moderate contamination in certain topsoil areas.Most As concentrations corresponded to grade II and grade III pollution levels.In contrast,Hg,Pb,and Cr concentrations remained within the safety standards established for agricultural products.However,Cd and As levels predominantly surpassed these safety thresholds.Notably,Guanba Village and Sidu Village exhibited significant pollution levels,warranting comprehensive investigations into the sources of contamination.[Conclusions]This study offers valuable insights for advancing the sustainable development of local agriculture and for the prevention and management of soil contamination.展开更多
This commentary critically appraises the study by Li et al which pioneered the exploration of the triglyceride-glucose(TyG)index as a prognostic marker in hepatitis B virus-related advanced hepatocellular carcinoma pa...This commentary critically appraises the study by Li et al which pioneered the exploration of the triglyceride-glucose(TyG)index as a prognostic marker in hepatitis B virus-related advanced hepatocellular carcinoma patients undergoing combined camrelizumab and lenvatinib therapy.While we acknowledge the study’s clinical relevance in proposing an easily accessible metabolic biomarker,we delve into the mechanistic plausibility linking insulin resistance to immunotherapy response and angiogenic inhibition.We further critically examine the methodological limitations,including the retrospective design,the populationspecific TyG cut-off value,and unaddressed metabolic confounders.We highlight the imperative for future research to validate its utility across diverse etiologies and treatment settings,and to unravel the underlying immunometabolic pathways.展开更多
AIM:To investigate the causal effect of obesity on cataract risk and explores the potential mediating roles of metabolites using Mendelian randomization(MR).METHODS:Summary-level data from large-scale genome-wide asso...AIM:To investigate the causal effect of obesity on cataract risk and explores the potential mediating roles of metabolites using Mendelian randomization(MR).METHODS:Summary-level data from large-scale genome-wide association studies to examine the relationship between obesity and cataract were utilized.Obesity-related traits,including body mass index(BMI),waist-to-hip ratio(WHR),and waist circumference(WC).A two-sample MR approach was employed to assess the causal effect of obesity on cataract risk,while potential mediators were identified from suitable genome-wide association studies(GWAS)datasets.Additionally,a metabolic pathway analysis was conducted.RESULTS:An increase of 1 standard deviation(SD)in BMI,WHR,and WC was associated with a significantly higher risk of cataract(BMI:odds ratio(OR)1.0017,95%confidence interval(CI):1.0001-1.0032,P=0.0320;WHR:OR 1.0029,95%CI:1.0006-1.0051,P=0.0129;WC:OR 1.0020,95%CI:1.0001-1.0038,P=0.0390].These associations remained robust after adjusting for confounding factors in multivariable MR analysis.Furthermore,a two-step MR analysis identified eight potential metabolic mediators,with one mediator showing a significant causal role in the relationship between obesity and cataract.CONCLUSION:This work highlights the importance of addressing obesity as a modifiable risk factor for cataracts,particularly through metabolic pathways.展开更多
BACKGROUND Timely and accurate evaluation of mental disorders in adolescents using appropriate mental health literacy assessment tools is essential for improving their mental health literacy levels.AIM To develop an e...BACKGROUND Timely and accurate evaluation of mental disorders in adolescents using appropriate mental health literacy assessment tools is essential for improving their mental health literacy levels.AIM To develop an evaluation index system for the mental health literacy of adolescent patients with mental disorders,providing a scientific,comprehensive,and reliable tool for the monitoring and intervention of mental health literacy of such patients.METHODS From December 2022 to June 2023,the evaluation index system for mental health literacy of adolescents with mental disorders was developed through literature reviews,semi-structured interviews,expert letter consultations,and the analytic hierarchy process.Based on this index system,a self-assessment questionnaire was compiled and administered to 305 adolescents with mental disorders to test the reliability and validity of the index system.RESULTS The final evaluation index system for mental health literacy of adolescents with mental disorders included 4 first-level indicators,10 second-level indicators,and 52 third-level indicators.The overall Cronbach’sαcoefficient of the index system was 0.957,with a partial reliability of 0.826 and a content validity index of 0.975.The cumulative variance contribution rate of 10 common factors was 66.491%.The correlation coefficients between each dimension and the total questionnaire ranged from 0.672 to 0.724,while the correlation coefficients in each dimension ranged from 0.389 to 0.705.CONCLUSION The evaluation index system for mental health literacy of adolescents with mental disorders,developed in this study,demonstrated notable reliability and validity,making it a valuable tool for evaluating mental health literacy in this population.展开更多
BACKGROUND Perioperative anesthesia management of obese patients presents significant challenges as traditional total body weight-based dosing fails to achieve optimal anesthetic effects due to altered pharmacokinetic...BACKGROUND Perioperative anesthesia management of obese patients presents significant challenges as traditional total body weight-based dosing fails to achieve optimal anesthetic effects due to altered pharmacokinetic characteristics including abnormal drug distribution and clearance.Rocuronium exhibits markedly different distribution patterns in obese patients,with conventional weight correction methods inadequately addressing individual muscle mass variations that critically influence drug distribution.AIM To investigate the quantitative relationship between skeletal muscle index(SMI)and rocuronium distribution volume in obese colorectal cancer patients,establish a population pharmacokinetic model,and develop individualized dosing strategies based on muscle mass.METHODS A retrospective cohort study was conducted,including 100 obese patients(body mass index≥30 kg/m^(2))who underwent elective radical colorectal cancer surgery at our hospital from June 2023 to January 2025.Skeletal muscle mass was measured using InBody 260 body composition analyzer and SMI was calculated to assess muscle mass,with male SMI<7.0 kg/m^(2) and female SMI<5.7 kg/m^(2)as diagnostic criteria for sarcopenia.Plasma rocuronium concentrations were detected by liquid chromatography-tandem mass spectrometry/mass spectrometry,and nonlinear mixed-effect modeling was used to establish population pharmacokinetic modeling.Stepwise regression was used to screen covariates,and dosing regimens were optimized through Monte Carlo simulation.The primary endpoint was targeted plasma concentration achievement rate,and the secondary endpoint was postoperative residual muscle relaxation incidence.RESULTS Among 100 patients,35(35.0%)had sarcopenia and 65(65.0%)did not.Patients in the sarcopenia group were older(64.1±9.8 years vs 54.2±10.9 years,P<0.001)and had significantly lower SMI(6.2±0.8 kg/m^(2)vs 8.4±1.2 kg/m^(2),P<0.001).SMI showed strong positive correlation with rocuronium steady-state distribution volume(r=0.718,P<0.001)and moderate negative correlation with clearance(r=-0.502,P<0.001).A two-compartment population pharmacokinetic model was successfully established,with SMI being the most important covariate affecting central compartment distribution volume(△OFV=-41.2,P<0.001).Model validation showed bootstrap successful convergence rate of 92.3%,and 92.1%of observed values fell within prediction intervals in predicted concentration versus predicted concentration.The SMI-based individualized dosing regimen improved target exposure achievement rate from 82.0%in traditional regimen to 93.5%(P=0.009),and reduced postoperative residual muscle relaxation incidence from 13.0%to 3.5%(P=0.018).The sarcopenia group showed the most significant improvement in achievement rate,from 71.4%to 93.8%(P=0.017).CONCLUSION SMI shows strong correlation with rocuronium distribution volume in obese colorectal cancer patients and is a key factor affecting drug distribution.SMI-based individualized dosing strategies can significantly improve target exposure achievement rate and reduce postoperative residual muscle relaxation incidence,providing scientific evidence for precision anesthesia management in obese patients.展开更多
This paper proposes a threat assessment framework for non-cooperative satellites by analyzing their motion characteristics,developing a quantitative evaluation methodology,and demonstrating its effectiveness via repre...This paper proposes a threat assessment framework for non-cooperative satellites by analyzing their motion characteristics,developing a quantitative evaluation methodology,and demonstrating its effectiveness via representative scenarios with neural network acceleration.The framework first establishes a threat evaluation model that integrates three core parameters:capability,opportunity,and hidden values.Subsequently,this research systematically investigates the critical role of transfer windows in threat quantification and introduces a transfer window-based threat assessment approach.The proposed methodology is validated through multiple representative scenarios,with simulation results demonstrating superior performance compared to conventional methods relying solely on optimal transfer windows or minimum distance metrics,enabling more nuanced threat ranking in scenarios where traditional techniques prove inadequate.To address computational demands,a neural networkbased approximation system is implemented to achieve a 25,200×speedup(0.005 s vs.baseline 126 s per 1000-sample batch)through parallel processing,maintaining 99.3%accuracy.Finally,the study explores the framework's extensibility to diverse NCS objectives.It identifies discrepancies between intention inference models and threat evaluation paradigms,providing methodological insights for next-generation space domain awareness systems.展开更多
Let G be a finite group and H a subgroup of G.The normal index of H in G is defined as the order of K/H_(G),where K is a normal supplement of H in G such that|K|is minimal and H_(G)≤K■G.Let p be a prime which divide...Let G be a finite group and H a subgroup of G.The normal index of H in G is defined as the order of K/H_(G),where K is a normal supplement of H in G such that|K|is minimal and H_(G)≤K■G.Let p be a prime which divides the order of a group G.In this paper,some characterizations of G being p-solvable or p-supersolvable were obtained by analyzing the normal index of certain subgroups of G.These results can be viewed as local version of recent results in the literature.展开更多
Arteriovenous fistula(AVF)calcification is a common complication in hemodialysis patients that leads to AVF dysfunction and decreases the AVF survival,but the mechanisms of AVF calcification,especially the role of hem...Arteriovenous fistula(AVF)calcification is a common complication in hemodialysis patients that leads to AVF dysfunction and decreases the AVF survival,but the mechanisms of AVF calcification,especially the role of hemodynamic changes in AVF calcification have not been fully investigated.In this study,a computational fluid dynamics(CFD)model was carried out based on AVF,at the distal anastomosis of the cephalic vein and radial artery,generated from a patient-specific computed tomography(CT)angiography and Doppler ultrasound image.Hemodynamic factors were considered to explore the mechanisms responsible for the initiation and progression of AVF calcification.Five stages in one cardiac cycle were chosen to be studied for the velocity field,pressure,time-averaged wall shear stress(TAWSS),and oscillatory shear index(OSI).Blood pressure was higher in the arteriovenous anastomosis,and variations of great amplitude of pressure were examined during the cardiac cycle.Blood pressure,transient shear stress,TAWSS,and OSI were higher in the arteriovenous anastomosis and at the bottom of expanded outflow vein,and these sites were highly consistent with the calcified areas shown on CT angiography.On the contrary,no calcification was found in sites where streamline was stable,blood pressure did not change dramatically,as well as TAWSS and OSI were lower.It was shown that AVF calcification was correlated with hemodynamic changes,which may contribute to further understanding the mechanisms of AVF calcification and providing scientific evidence to inform the optimization of surgical strategies and the development of personalized interventional measures in clinical contexts.展开更多
Addressing the widespread issues of internal fragmentation within protected areas and the neglect of surrounding critical habitat networks,this study aims to develop an assessment framework for the precise identificat...Addressing the widespread issues of internal fragmentation within protected areas and the neglect of surrounding critical habitat networks,this study aims to develop an assessment framework for the precise identification and remediation of regional conservation gaps.To this end,we introduce the Framework for Conservation Priority Identification(FCPI).The framework integrates Morphological Spatial Pattern Analysis(MSPA),the Remote Sensing Ecological Index(RSEI),Circuit Theory,and the Minimum Cumulative Resistance(MCR)model to formulate a multidimensional conservation priority index.This index facilitates the identification of critical ecological network components and enables the dynamic prioritization of conservation efforts.A case study of Fuzhou City from 2014 to 2020 reveals that despite an overall improvement in regional environmental quality,the functionality of core ecological sources has markedly declined.Between 2014 and 2020,the number of ecological sources grew by 76.9%,yet their total area shrank by 13.9%.Concurrently,the number of ecological corridors rose from 27 to 53,extending their total length by 380.23 km,which indicates an intensifying trend of habitat fragmentation.Furthermore,a significant number of crucial ecological network nodes,particularly within Minhou County,lie explicitly outside the existing protected area system.This confirms the presence of conservation gaps and unveils the spatiotemporal dynamics of shifting conservation priorities.The research validates that the proposed FCPI can effectively diagnose the dynamic deficiencies within conservation systems.It offers scientific decisionsupport for local governments,facilitating a transition from isolated conservation efforts towards systematic and comprehensive ecological network governance.展开更多
Gastric ulcer(GU)represents a clinically significant manifestation of peptic ulcer disease,driven by a complex interplay of microbial,environmental,and immuneinflammatory factors.A recent cross-sectional study by Shen...Gastric ulcer(GU)represents a clinically significant manifestation of peptic ulcer disease,driven by a complex interplay of microbial,environmental,and immuneinflammatory factors.A recent cross-sectional study by Shen et al systematically evaluated six complete blood count-derived inflammatory indices:Neutrophil-tolymphocyte ratio,monocyte-to-lymphocyte ratio,platelet-to-lymphocyte ratio,systemic immune-inflammation index,systemic inflammatory response index(SIRI),and aggregate index of systemic inflammation and demonstrated their positive associations with GU prevalence,identifying SIRI as the strongest predictor.This editorial contextualizes these findings within the broader literature,clarifies that these indices reflect systemic rather than GU-specific inflammation,highlights methodological strengths and major limitations,and proposes a conceptual clinical algorithm for integrating SIRI into GU risk assessment.Future multicenter studies incorporating Helicobacter pylori infection,non-steroidal antiinflammatory drug exposure,and prospective design are essential to validate and translate these findings into clinical practice.展开更多
AIM:To investigate the association between anti-DFS70 antibody positivity and ocular parameters,specifically,the choroidal vascularity index(CVI)and other optical coherence tomography(OCT)metrics,in a healthy populati...AIM:To investigate the association between anti-DFS70 antibody positivity and ocular parameters,specifically,the choroidal vascularity index(CVI)and other optical coherence tomography(OCT)metrics,in a healthy population.METHODS:This age-and sex-matched case-control study enrolled 84 healthy individuals with positive anti-DFS70 antibody findings and 84 healthy negative controls.All participants underwent detailed ophthalmological examinations,including biometry and OCT imaging.Anti-DFS70 positivity was determined by indirect immunofluorescence and scored semi-quantitatively(1+to 3+).CVI was calculated from OCT images using a standardized protocol with Image J software.Statistical analyses,including Student’s t-test,Mann-Whitney U test,Spearman correlation,and logistic regression,were used to compare groups and identify predictive factors.RESULTS:The individuals who tested positive and negative for anti-DFS70 included in the study were matched for age(median age=47y)and sex(F:M=7:1).CVI was significantly lower in the anti-DFS70-positive group compared to the negative group.A higher anti-DFS70 antibody titer was significantly associated with decreased subfoveal and nasal choroidal thickness(P=0.016 and P=0.014,respectively).In univariate regression analysis,CVI was the only significant predictor of anti-DFS70 positivity[odds ratio(OR)=0.02,P=0.025].Multivariate analysis revealed a positive correlation between macular thinning outside the subfoveal area and anti-DFS70 status(P<0.05).CONCLUSION:Our study demonstrates a novel association between anti-DFS70 antibody positivity and reduced choroidal vascularity in healthy individuals.These findings suggest that anti-DFS70 antibodies may be associated with subtle choroidal vascular changes detectable by OCT,even in asymptomatic individuals.Further longitudinal research is warranted to clarify the underlying mechanisms and long-term clinical significance of these ocular changes.展开更多
Seasonal cycles are essential components of weather and climatic systems. This study utilized observational data from a meteorological station on an island in the South China Sea from 1961 to 2020, along with ERA5 rea...Seasonal cycles are essential components of weather and climatic systems. This study utilized observational data from a meteorological station on an island in the South China Sea from 1961 to 2020, along with ERA5 reanalysis data, to explore the variations in seasonal cycles and thermal comfort characteristics on the island. The observational data revealed that the onset of summer on the island occurred earlier each year, whereas the onset of autumn was gradually delayed,leading to an increase in the duration of summer. Urbanization had played an important role in elevating local temperatures and extending the duration of summer. The thermal comfort index exhibited a clear upward trend annually, reflecting a shift towards warmer and less comfortable conditions due to urbanization. From 1961 to 2020, the annual average thermal comfort index indicated that 36 years(60%) were characterized by hot discomfort, and 24 years(40%) were within the comfortable range. The number of comfortable days per year on the island exhibited a declining trend. Urbanization markedly influenced the thermal comfort levels on the island, contributing to an annual increase in the number of hot discomfort days. However, the reanalysis data did not reflect the actual observed changes in the comfort characteristics on the island.展开更多
AIM:To evaluate the predictive value of pan-immuneinflammation value(PIV)in the diagnosis of proliferative diabetic retinopathy(PDR)and its association with the stage of PDR.METHODS:This observational case-control stu...AIM:To evaluate the predictive value of pan-immuneinflammation value(PIV)in the diagnosis of proliferative diabetic retinopathy(PDR)and its association with the stage of PDR.METHODS:This observational case-control study included participants who underwent routine complete blood count testing.Inflammation-related indices,including neutrophil-to-lymphocyte ratio,systemic immune-inflammation index(SII),and PIV,were derived and analyzed.Receiver operating characteristic curve(ROC)analysis was applied to assess the diagnostic performance of these indices in distinguishing patients with PDR,with sensitivity,specificity,area under ROC,and optimal threshold values calculated.In addition,binary logistic regression analysis was performed to evaluate the association between inflammatory indices and PDR stage.RESULTS:This study included 205 patients:60 with diabetes without retinopathy(mean age:61.81±10.76y),80 with PDR(mean age:61.63±10.03y)and 65 healthy controls(mean age:59.52±5.88y).The PDR group had significantly higher white blood cell(WBC,P<0.001),monocyte(MONO,P=0.009)and neutrophil(NEU)counts(P<0.001).SII and PIV had the highest sensitivity and area under ROC for predicting patients with PDR(0.822,0.846,respectively).The optimal cut-off values for discriminating patients with PDR were determined to be>527.12 and>299.08 for SII and PIV,respectively.The logistic regression analysis demonstrated that a decrease in lymphocyte(LYM)count and an increase in platelet count(PLT),glycated haemoglobin(HbA1c),SII,and PIV were all significantly associated with the development of high-risk PDR(all P<0.05).PIV was more stable than independent MONO,LYM,PLT and NEU levels in predicting both the diagnosis and stage of PDR.The optimal cut-off value for PIV to discriminate patients with high-risk PDR was found to be>345.87 area under ROC=0.871,with sensitivity of 0.827 and specificity of 0.812.CONCLUSION:PIV is a reliable,valuable,and inexpensive blood index that can be used for early detection and staging of PDR.PIV may therefore be essential to be used for the follow-up of diabetic patients.展开更多
The Journal of Acupuncture and Tuina Science,a peerreview journal with an international scope(ISSN 1672-3597,CN 31-1908/R,Bimonthly),is indexed in Emerging Sources Citation Index(ESCI),Western Pacific Region Index Med...The Journal of Acupuncture and Tuina Science,a peerreview journal with an international scope(ISSN 1672-3597,CN 31-1908/R,Bimonthly),is indexed in Emerging Sources Citation Index(ESCI),Western Pacific Region Index Medicus(WPRIM),Springer-Verlag GmbH Database,Index of Copernicus(IC),Chemical Abstracts(CA),Chinese Science Citation Database(CSCD),and Chinese Scientific and Technical Papers and Citations Database(CSTPCD).You can search the text on https://link.springer.com/journal/11726.展开更多
AIM:To explore the repeatability,reproducibility,and agreement in the measurement of the choroidal vascularity index(CVI)for different swept-source optical coherence tomography(OCT)devices and between OCT and OCT angi...AIM:To explore the repeatability,reproducibility,and agreement in the measurement of the choroidal vascularity index(CVI)for different swept-source optical coherence tomography(OCT)devices and between OCT and OCT angiography(OCTA)images.METHODS:Two swept-source OCT imaging systems,VG200I and Topcon DRI OCT Triton,were used to capture OCT and OCTA images in triplicate.The first and third images were taken by one operator,and the second image was taken by another operator.The built-in software was used to calculate the CVI from the OCTA images(CVI-OCTA),and a custom-designed algorithm was used to calculate the CVI from the OCT images(CVI-OCT).Repeatability and reproducibility were assessed with the intraclass correlation coefficient(ICC),and agreement between devices and between OCT and OCTA were evaluated with Bland-Altman analysis.RESULTS:Sixty-eight eyes from 35 adults(17 females)were included in the analysis.The average age of the participants was 23.6±2.3y,with an average spherical equivalent refraction of-3.08±2.47 D and an average AL of 25.21±1.20 mm.Both OCT devices demonstrated high repeatability and reproducibility in measuring the CVI-OCTA(all ICCs>0.894 across five choroidal regions)and CVI-OCT(all ICCs>0.838).Furthermore,the between-device agreement in measuring the CVI-OCT was good[mean difference(MD)ranging from-2.32%to-3.07%],but that in measuring the CVI-OCTA was poor(MD,1.48%to-7.43%).Additionally,the between-imaging agreement(CVI-OCTA versus CVI-OCT)was poor for both devices(Triton,MD,6.05%to 12.68%;VG200I,MD,6.67%to 12.09%).CONCLUSION:Both OCT devices and the two analytical methods demonstrate good stability.The inter-device consistency of CVI-OCT is good,while the inter-device consistency of CVI-OCTA and the consistency between the two analytical methods in the same device are both poor.展开更多
The Chinese Journal of Natural Medicines(CJNM,ISSN 2095-6975),founded in 2003 and sponsored by China Pharmaceutical University,is a peer-reviewed journal published monthly in print by Science Press and online by Elsev...The Chinese Journal of Natural Medicines(CJNM,ISSN 2095-6975),founded in 2003 and sponsored by China Pharmaceutical University,is a peer-reviewed journal published monthly in print by Science Press and online by Elsevier.CJNM is currently indexed in Science Citation Index Expanded(SCIE),MEDLINE,BIOSIS Previews,BIOSIS Toxicology,CAB Abstracts.展开更多
The growing demand for renewable energy has increased the use of wood pellets as a clean and efficient biomass fuel.This study aims to evaluate the physical properties of wood pellets produced from Acacia hybrid(AC)ve...The growing demand for renewable energy has increased the use of wood pellets as a clean and efficient biomass fuel.This study aims to evaluate the physical properties of wood pellets produced from Acacia hybrid(AC)veneer waste and Pine wood(PW)waste mixed with varying ratios.The objectives are to investigate the effect of different blend ratios ofAcacia hybrid veneer waste and pine wood waste on the physical properties,specificallymoisture content,density,and pellet durability index(PDI)of wood pellets,and to identify the optimal ratio that yields the most desirable pellet quality.The wood pellets were produced by blending Acacia hybrid veneer waste and Pine wood waste(AC:PW)in weight ratios of 100:0,75:25,50:50,25:75,and 0:100.The materials were dried to 10%–12%moisture before pelletizing using a pellet mill under consistent pressure and temperature.Moisture content(MC),density(ρ)and pellet durability index(PDI)were measured following the International Organization for Standardization(ISO).The study found that blending Acacia hybrid veneer waste with Pine wood waste significantly improved pellet density and durability compared to the control.The moisture was lowest in pellets with 50:50 and 25:75 blends,indicating better drying and stability.The blend 50:50 achieves the highest density,and for pellet durability index,the best blend is 25:75,suggesting improved resistance to breakage.Overall,the 50:50 and 25:75 ratios produced pellet with the most desirable combination of low moisture,high density,high durability and the blend meets key ISO 17225 and ENplus quality standards for industrial wood pellet.展开更多
基金Supported by Ningbo NSF(No.2021J234)Zhejiang Provincial Philosophy and Social Sciences Planning Project(No.24NDJC057YB)。
文摘The atom-bond sum-connectivity(ABS)index,put forward by[J.Math.Chem.,2022,60(10):20812093],exhibits a strong link with the acentric factor of octane isomers.The experimental physico-chemical properties of octane isomers,such as boiling point,of formation are found to be better measured by the ABS index than by the Randi,atom-bond connectivity(ABC),and sum-connectivity(SC)indices.One important source of information for researching the molecular structure is the bounds for its topological indices.The extrema of the ABS index of the line,total,and Mycielski graphs are calculated in this work.Moreover,the pertinent extremal graphs were illustrated.
文摘The Gabes aquifer system,located in southeastern Tunisia,is a crucial resource for supporting local socio-economic activities.Due to its dual porosity structure,is particularly vulnerable to pollution.This study aims to develop a hybrid model that combines the Fracture Aquifer Index(FAI)with the conventional GOD(Groundwater occurrence,Overall lithology,Depth to water table)method,to assess groundwater vulnerability in fractured aquifer.To develop the hybrid model,the classical GOD method was integrated with FAI to produce a single composite index.Each parameter within both GOD and FAI was scored,and a final index was calculated to delineate vulnerable areas.The results show that the study area can be classified into four vulnerability levels:Very low,low,moderate,and high,indicating that approximately 8%of the area exhibits very low vulnerability,29%has low vulnerability,25%falls into the moderate category,and 38%is considered highly vulnerable.The FAI-GOD model further incorporates fracture network characteristics.This refinement reduces the classification to three vulnerability classes:Low,medium,and high.The outcomes demonstrate that 46%of the area is highly vulnerable due to a dense concentration of fractures,while 17%represents an intermediate zone characterized by either shallow or deeper fractures.In contrast,37%corresponds to areas with lightly fractured rock,where the impact on vulnerability is minimal.Multivariate statistical analysis was employed using Principal Components Analysis(PCA)and Hierarchical Cluster Analysis(HCA)on 24 samples across six variables.The first three components account for over 76%of the total variance,reinforcing the significance of fracture dynamics in classifying vulnerability levels.The FAI-GOD model removes the very-low-vulnerability class and expands the spatial extent of low-and high-vulnerability zones,reflecting the dominant influence of fracture networks on aquifer sensitivity.While both indices use a five-class system,FAI-GOD redistributes vulnerability by eliminating very-low-vulnerability areas and amplifying low/high categories,highlighting the critical role of fractures.A strong correlation(R2=0.94)between the GOD and FAI-GOD indices,demonstrated through second-order polynomial regression,confirms the robustness of the FAI-GOD model in accurately predicting vulnerability to pollution.This model provides a useful framework for assessing the vulnerability of complex aquifers and serves as a decision-making tool for groundwater managers in similar areas.
基金Supported by Undergraduate Innovation and Entrepreneurship Training Program of Guizhou Province(2024106640823)Natural Science Research Project of Guizhou Provincial Department of Education(QJJ[2023]043)Zunyi Science and Technology Innovation Team Project(ZKCTD008).
文摘[Objectives]To analyze the current status of heavy metal contamination in soils of vegetable cultivation bases located in Huichuan District,Zunyi City.[Methods]Soil samples from various depths within the vegetable cultivation bases of Guanba Village,Sidu Village,and Banqiao Village in Huichuan District,Zunyi City,were selected as the subjects of this study.The concentrations of five heavy metals,including lead(Pb),mercury(Hg),cadmium(Cd),arsenic(As),and chromium(Cr),were measured at different soil depths.The Nemerow comprehensive pollution index method was employed to assess heavy metal contamination,and the analysis was conducted in accordance with the farmland environmental quality evaluation standards for edible agricultural products.[Results]The concentrations of Cd and As at the sample collection sites were relatively elevated.The pollution level of Cd reached grade III or above,indicating moderate contamination in certain topsoil areas.Most As concentrations corresponded to grade II and grade III pollution levels.In contrast,Hg,Pb,and Cr concentrations remained within the safety standards established for agricultural products.However,Cd and As levels predominantly surpassed these safety thresholds.Notably,Guanba Village and Sidu Village exhibited significant pollution levels,warranting comprehensive investigations into the sources of contamination.[Conclusions]This study offers valuable insights for advancing the sustainable development of local agriculture and for the prevention and management of soil contamination.
文摘This commentary critically appraises the study by Li et al which pioneered the exploration of the triglyceride-glucose(TyG)index as a prognostic marker in hepatitis B virus-related advanced hepatocellular carcinoma patients undergoing combined camrelizumab and lenvatinib therapy.While we acknowledge the study’s clinical relevance in proposing an easily accessible metabolic biomarker,we delve into the mechanistic plausibility linking insulin resistance to immunotherapy response and angiogenic inhibition.We further critically examine the methodological limitations,including the retrospective design,the populationspecific TyG cut-off value,and unaddressed metabolic confounders.We highlight the imperative for future research to validate its utility across diverse etiologies and treatment settings,and to unravel the underlying immunometabolic pathways.
基金Supported by the National Natural Science Foundation of China(No.82501261)Medical Research Projects of the Jiangsu Provincial Health Commission(No.M2024041).
文摘AIM:To investigate the causal effect of obesity on cataract risk and explores the potential mediating roles of metabolites using Mendelian randomization(MR).METHODS:Summary-level data from large-scale genome-wide association studies to examine the relationship between obesity and cataract were utilized.Obesity-related traits,including body mass index(BMI),waist-to-hip ratio(WHR),and waist circumference(WC).A two-sample MR approach was employed to assess the causal effect of obesity on cataract risk,while potential mediators were identified from suitable genome-wide association studies(GWAS)datasets.Additionally,a metabolic pathway analysis was conducted.RESULTS:An increase of 1 standard deviation(SD)in BMI,WHR,and WC was associated with a significantly higher risk of cataract(BMI:odds ratio(OR)1.0017,95%confidence interval(CI):1.0001-1.0032,P=0.0320;WHR:OR 1.0029,95%CI:1.0006-1.0051,P=0.0129;WC:OR 1.0020,95%CI:1.0001-1.0038,P=0.0390].These associations remained robust after adjusting for confounding factors in multivariable MR analysis.Furthermore,a two-step MR analysis identified eight potential metabolic mediators,with one mediator showing a significant causal role in the relationship between obesity and cataract.CONCLUSION:This work highlights the importance of addressing obesity as a modifiable risk factor for cataracts,particularly through metabolic pathways.
基金Supported by Inter Disciplinary Direction Cultivation Project of Hunan University of Chinese Medicine,No.2025JC01032025 Hunan Province Science and Technology Innovation Plan Project,No.2025RC9012+2 种基金2022"Unveiling and Leading"Project of Discipline Construction at Hunan University of Chinese Medicine,No.22JBZ044Changsha Municipal Natural Science Foundation,No.kq2402174Hunan Provincial Science Popularization Fund Project,No.2025ZK4223.
文摘BACKGROUND Timely and accurate evaluation of mental disorders in adolescents using appropriate mental health literacy assessment tools is essential for improving their mental health literacy levels.AIM To develop an evaluation index system for the mental health literacy of adolescent patients with mental disorders,providing a scientific,comprehensive,and reliable tool for the monitoring and intervention of mental health literacy of such patients.METHODS From December 2022 to June 2023,the evaluation index system for mental health literacy of adolescents with mental disorders was developed through literature reviews,semi-structured interviews,expert letter consultations,and the analytic hierarchy process.Based on this index system,a self-assessment questionnaire was compiled and administered to 305 adolescents with mental disorders to test the reliability and validity of the index system.RESULTS The final evaluation index system for mental health literacy of adolescents with mental disorders included 4 first-level indicators,10 second-level indicators,and 52 third-level indicators.The overall Cronbach’sαcoefficient of the index system was 0.957,with a partial reliability of 0.826 and a content validity index of 0.975.The cumulative variance contribution rate of 10 common factors was 66.491%.The correlation coefficients between each dimension and the total questionnaire ranged from 0.672 to 0.724,while the correlation coefficients in each dimension ranged from 0.389 to 0.705.CONCLUSION The evaluation index system for mental health literacy of adolescents with mental disorders,developed in this study,demonstrated notable reliability and validity,making it a valuable tool for evaluating mental health literacy in this population.
文摘BACKGROUND Perioperative anesthesia management of obese patients presents significant challenges as traditional total body weight-based dosing fails to achieve optimal anesthetic effects due to altered pharmacokinetic characteristics including abnormal drug distribution and clearance.Rocuronium exhibits markedly different distribution patterns in obese patients,with conventional weight correction methods inadequately addressing individual muscle mass variations that critically influence drug distribution.AIM To investigate the quantitative relationship between skeletal muscle index(SMI)and rocuronium distribution volume in obese colorectal cancer patients,establish a population pharmacokinetic model,and develop individualized dosing strategies based on muscle mass.METHODS A retrospective cohort study was conducted,including 100 obese patients(body mass index≥30 kg/m^(2))who underwent elective radical colorectal cancer surgery at our hospital from June 2023 to January 2025.Skeletal muscle mass was measured using InBody 260 body composition analyzer and SMI was calculated to assess muscle mass,with male SMI<7.0 kg/m^(2) and female SMI<5.7 kg/m^(2)as diagnostic criteria for sarcopenia.Plasma rocuronium concentrations were detected by liquid chromatography-tandem mass spectrometry/mass spectrometry,and nonlinear mixed-effect modeling was used to establish population pharmacokinetic modeling.Stepwise regression was used to screen covariates,and dosing regimens were optimized through Monte Carlo simulation.The primary endpoint was targeted plasma concentration achievement rate,and the secondary endpoint was postoperative residual muscle relaxation incidence.RESULTS Among 100 patients,35(35.0%)had sarcopenia and 65(65.0%)did not.Patients in the sarcopenia group were older(64.1±9.8 years vs 54.2±10.9 years,P<0.001)and had significantly lower SMI(6.2±0.8 kg/m^(2)vs 8.4±1.2 kg/m^(2),P<0.001).SMI showed strong positive correlation with rocuronium steady-state distribution volume(r=0.718,P<0.001)and moderate negative correlation with clearance(r=-0.502,P<0.001).A two-compartment population pharmacokinetic model was successfully established,with SMI being the most important covariate affecting central compartment distribution volume(△OFV=-41.2,P<0.001).Model validation showed bootstrap successful convergence rate of 92.3%,and 92.1%of observed values fell within prediction intervals in predicted concentration versus predicted concentration.The SMI-based individualized dosing regimen improved target exposure achievement rate from 82.0%in traditional regimen to 93.5%(P=0.009),and reduced postoperative residual muscle relaxation incidence from 13.0%to 3.5%(P=0.018).The sarcopenia group showed the most significant improvement in achievement rate,from 71.4%to 93.8%(P=0.017).CONCLUSION SMI shows strong correlation with rocuronium distribution volume in obese colorectal cancer patients and is a key factor affecting drug distribution.SMI-based individualized dosing strategies can significantly improve target exposure achievement rate and reduce postoperative residual muscle relaxation incidence,providing scientific evidence for precision anesthesia management in obese patients.
基金supported by the National Key R&D Programof China:Gravitational Wave Detection Project(Grant Nos.2021YFC2026,2021YFC2202601,2021YFC2202603)the Na-tional Natural Science Foundation of China(Grant Nos.12172288and 12472046)。
文摘This paper proposes a threat assessment framework for non-cooperative satellites by analyzing their motion characteristics,developing a quantitative evaluation methodology,and demonstrating its effectiveness via representative scenarios with neural network acceleration.The framework first establishes a threat evaluation model that integrates three core parameters:capability,opportunity,and hidden values.Subsequently,this research systematically investigates the critical role of transfer windows in threat quantification and introduces a transfer window-based threat assessment approach.The proposed methodology is validated through multiple representative scenarios,with simulation results demonstrating superior performance compared to conventional methods relying solely on optimal transfer windows or minimum distance metrics,enabling more nuanced threat ranking in scenarios where traditional techniques prove inadequate.To address computational demands,a neural networkbased approximation system is implemented to achieve a 25,200×speedup(0.005 s vs.baseline 126 s per 1000-sample batch)through parallel processing,maintaining 99.3%accuracy.Finally,the study explores the framework's extensibility to diverse NCS objectives.It identifies discrepancies between intention inference models and threat evaluation paradigms,providing methodological insights for next-generation space domain awareness systems.
基金Supported by the National Natural Science Foundation of China(Grant No.12071092)Guangdong Basic and Applied Basic Research Foundation(Grant No.2025A1515012072)+1 种基金the Natural Science Research Project of Anhui Educational Committee(Grant No.2024AH051298)the Scientific Research Foundation of Bozhou University(Grant No.BYKQ202419).
文摘Let G be a finite group and H a subgroup of G.The normal index of H in G is defined as the order of K/H_(G),where K is a normal supplement of H in G such that|K|is minimal and H_(G)≤K■G.Let p be a prime which divides the order of a group G.In this paper,some characterizations of G being p-solvable or p-supersolvable were obtained by analyzing the normal index of certain subgroups of G.These results can be viewed as local version of recent results in the literature.
基金supported by the Scientific Program of Tianjin Municipal Education Commission(Natural Science,Grant No.2022KJ254)Science Foundation of the Second Hospital of Tianjin Medical University(Grant No.2021ydey05)Tianjin Municipal Health Commission Integrated Traditional Chinese and Western Medicine Project(Grant No.2021173).
文摘Arteriovenous fistula(AVF)calcification is a common complication in hemodialysis patients that leads to AVF dysfunction and decreases the AVF survival,but the mechanisms of AVF calcification,especially the role of hemodynamic changes in AVF calcification have not been fully investigated.In this study,a computational fluid dynamics(CFD)model was carried out based on AVF,at the distal anastomosis of the cephalic vein and radial artery,generated from a patient-specific computed tomography(CT)angiography and Doppler ultrasound image.Hemodynamic factors were considered to explore the mechanisms responsible for the initiation and progression of AVF calcification.Five stages in one cardiac cycle were chosen to be studied for the velocity field,pressure,time-averaged wall shear stress(TAWSS),and oscillatory shear index(OSI).Blood pressure was higher in the arteriovenous anastomosis,and variations of great amplitude of pressure were examined during the cardiac cycle.Blood pressure,transient shear stress,TAWSS,and OSI were higher in the arteriovenous anastomosis and at the bottom of expanded outflow vein,and these sites were highly consistent with the calcified areas shown on CT angiography.On the contrary,no calcification was found in sites where streamline was stable,blood pressure did not change dramatically,as well as TAWSS and OSI were lower.It was shown that AVF calcification was correlated with hemodynamic changes,which may contribute to further understanding the mechanisms of AVF calcification and providing scientific evidence to inform the optimization of surgical strategies and the development of personalized interventional measures in clinical contexts.
基金supported by the Natural Science Foundation of Fujian Province(2023J01434)the Science and Technology Innovation Special Fund Project of Fujian Agriculture and Forestry University(KFb22028XA)。
文摘Addressing the widespread issues of internal fragmentation within protected areas and the neglect of surrounding critical habitat networks,this study aims to develop an assessment framework for the precise identification and remediation of regional conservation gaps.To this end,we introduce the Framework for Conservation Priority Identification(FCPI).The framework integrates Morphological Spatial Pattern Analysis(MSPA),the Remote Sensing Ecological Index(RSEI),Circuit Theory,and the Minimum Cumulative Resistance(MCR)model to formulate a multidimensional conservation priority index.This index facilitates the identification of critical ecological network components and enables the dynamic prioritization of conservation efforts.A case study of Fuzhou City from 2014 to 2020 reveals that despite an overall improvement in regional environmental quality,the functionality of core ecological sources has markedly declined.Between 2014 and 2020,the number of ecological sources grew by 76.9%,yet their total area shrank by 13.9%.Concurrently,the number of ecological corridors rose from 27 to 53,extending their total length by 380.23 km,which indicates an intensifying trend of habitat fragmentation.Furthermore,a significant number of crucial ecological network nodes,particularly within Minhou County,lie explicitly outside the existing protected area system.This confirms the presence of conservation gaps and unveils the spatiotemporal dynamics of shifting conservation priorities.The research validates that the proposed FCPI can effectively diagnose the dynamic deficiencies within conservation systems.It offers scientific decisionsupport for local governments,facilitating a transition from isolated conservation efforts towards systematic and comprehensive ecological network governance.
基金Supported by the National Natural Science Foundation of China,No.82170406 and No.81970238.
文摘Gastric ulcer(GU)represents a clinically significant manifestation of peptic ulcer disease,driven by a complex interplay of microbial,environmental,and immuneinflammatory factors.A recent cross-sectional study by Shen et al systematically evaluated six complete blood count-derived inflammatory indices:Neutrophil-tolymphocyte ratio,monocyte-to-lymphocyte ratio,platelet-to-lymphocyte ratio,systemic immune-inflammation index,systemic inflammatory response index(SIRI),and aggregate index of systemic inflammation and demonstrated their positive associations with GU prevalence,identifying SIRI as the strongest predictor.This editorial contextualizes these findings within the broader literature,clarifies that these indices reflect systemic rather than GU-specific inflammation,highlights methodological strengths and major limitations,and proposes a conceptual clinical algorithm for integrating SIRI into GU risk assessment.Future multicenter studies incorporating Helicobacter pylori infection,non-steroidal antiinflammatory drug exposure,and prospective design are essential to validate and translate these findings into clinical practice.
文摘AIM:To investigate the association between anti-DFS70 antibody positivity and ocular parameters,specifically,the choroidal vascularity index(CVI)and other optical coherence tomography(OCT)metrics,in a healthy population.METHODS:This age-and sex-matched case-control study enrolled 84 healthy individuals with positive anti-DFS70 antibody findings and 84 healthy negative controls.All participants underwent detailed ophthalmological examinations,including biometry and OCT imaging.Anti-DFS70 positivity was determined by indirect immunofluorescence and scored semi-quantitatively(1+to 3+).CVI was calculated from OCT images using a standardized protocol with Image J software.Statistical analyses,including Student’s t-test,Mann-Whitney U test,Spearman correlation,and logistic regression,were used to compare groups and identify predictive factors.RESULTS:The individuals who tested positive and negative for anti-DFS70 included in the study were matched for age(median age=47y)and sex(F:M=7:1).CVI was significantly lower in the anti-DFS70-positive group compared to the negative group.A higher anti-DFS70 antibody titer was significantly associated with decreased subfoveal and nasal choroidal thickness(P=0.016 and P=0.014,respectively).In univariate regression analysis,CVI was the only significant predictor of anti-DFS70 positivity[odds ratio(OR)=0.02,P=0.025].Multivariate analysis revealed a positive correlation between macular thinning outside the subfoveal area and anti-DFS70 status(P<0.05).CONCLUSION:Our study demonstrates a novel association between anti-DFS70 antibody positivity and reduced choroidal vascularity in healthy individuals.These findings suggest that anti-DFS70 antibodies may be associated with subtle choroidal vascular changes detectable by OCT,even in asymptomatic individuals.Further longitudinal research is warranted to clarify the underlying mechanisms and long-term clinical significance of these ocular changes.
基金National Natural Science Foundation of China(U21A6001,42475077)Innovation Platform for Academicians of Hainan Province。
文摘Seasonal cycles are essential components of weather and climatic systems. This study utilized observational data from a meteorological station on an island in the South China Sea from 1961 to 2020, along with ERA5 reanalysis data, to explore the variations in seasonal cycles and thermal comfort characteristics on the island. The observational data revealed that the onset of summer on the island occurred earlier each year, whereas the onset of autumn was gradually delayed,leading to an increase in the duration of summer. Urbanization had played an important role in elevating local temperatures and extending the duration of summer. The thermal comfort index exhibited a clear upward trend annually, reflecting a shift towards warmer and less comfortable conditions due to urbanization. From 1961 to 2020, the annual average thermal comfort index indicated that 36 years(60%) were characterized by hot discomfort, and 24 years(40%) were within the comfortable range. The number of comfortable days per year on the island exhibited a declining trend. Urbanization markedly influenced the thermal comfort levels on the island, contributing to an annual increase in the number of hot discomfort days. However, the reanalysis data did not reflect the actual observed changes in the comfort characteristics on the island.
文摘AIM:To evaluate the predictive value of pan-immuneinflammation value(PIV)in the diagnosis of proliferative diabetic retinopathy(PDR)and its association with the stage of PDR.METHODS:This observational case-control study included participants who underwent routine complete blood count testing.Inflammation-related indices,including neutrophil-to-lymphocyte ratio,systemic immune-inflammation index(SII),and PIV,were derived and analyzed.Receiver operating characteristic curve(ROC)analysis was applied to assess the diagnostic performance of these indices in distinguishing patients with PDR,with sensitivity,specificity,area under ROC,and optimal threshold values calculated.In addition,binary logistic regression analysis was performed to evaluate the association between inflammatory indices and PDR stage.RESULTS:This study included 205 patients:60 with diabetes without retinopathy(mean age:61.81±10.76y),80 with PDR(mean age:61.63±10.03y)and 65 healthy controls(mean age:59.52±5.88y).The PDR group had significantly higher white blood cell(WBC,P<0.001),monocyte(MONO,P=0.009)and neutrophil(NEU)counts(P<0.001).SII and PIV had the highest sensitivity and area under ROC for predicting patients with PDR(0.822,0.846,respectively).The optimal cut-off values for discriminating patients with PDR were determined to be>527.12 and>299.08 for SII and PIV,respectively.The logistic regression analysis demonstrated that a decrease in lymphocyte(LYM)count and an increase in platelet count(PLT),glycated haemoglobin(HbA1c),SII,and PIV were all significantly associated with the development of high-risk PDR(all P<0.05).PIV was more stable than independent MONO,LYM,PLT and NEU levels in predicting both the diagnosis and stage of PDR.The optimal cut-off value for PIV to discriminate patients with high-risk PDR was found to be>345.87 area under ROC=0.871,with sensitivity of 0.827 and specificity of 0.812.CONCLUSION:PIV is a reliable,valuable,and inexpensive blood index that can be used for early detection and staging of PDR.PIV may therefore be essential to be used for the follow-up of diabetic patients.
文摘The Journal of Acupuncture and Tuina Science,a peerreview journal with an international scope(ISSN 1672-3597,CN 31-1908/R,Bimonthly),is indexed in Emerging Sources Citation Index(ESCI),Western Pacific Region Index Medicus(WPRIM),Springer-Verlag GmbH Database,Index of Copernicus(IC),Chemical Abstracts(CA),Chinese Science Citation Database(CSCD),and Chinese Scientific and Technical Papers and Citations Database(CSTPCD).You can search the text on https://link.springer.com/journal/11726.
基金Supported by the National Key Research and Development Program of China(No.2022YFC3502503)the Medical and Health Science and Technology Project of the Zhejiang Provincial Health Commission of China(No.2022PY072).
文摘AIM:To explore the repeatability,reproducibility,and agreement in the measurement of the choroidal vascularity index(CVI)for different swept-source optical coherence tomography(OCT)devices and between OCT and OCT angiography(OCTA)images.METHODS:Two swept-source OCT imaging systems,VG200I and Topcon DRI OCT Triton,were used to capture OCT and OCTA images in triplicate.The first and third images were taken by one operator,and the second image was taken by another operator.The built-in software was used to calculate the CVI from the OCTA images(CVI-OCTA),and a custom-designed algorithm was used to calculate the CVI from the OCT images(CVI-OCT).Repeatability and reproducibility were assessed with the intraclass correlation coefficient(ICC),and agreement between devices and between OCT and OCTA were evaluated with Bland-Altman analysis.RESULTS:Sixty-eight eyes from 35 adults(17 females)were included in the analysis.The average age of the participants was 23.6±2.3y,with an average spherical equivalent refraction of-3.08±2.47 D and an average AL of 25.21±1.20 mm.Both OCT devices demonstrated high repeatability and reproducibility in measuring the CVI-OCTA(all ICCs>0.894 across five choroidal regions)and CVI-OCT(all ICCs>0.838).Furthermore,the between-device agreement in measuring the CVI-OCT was good[mean difference(MD)ranging from-2.32%to-3.07%],but that in measuring the CVI-OCTA was poor(MD,1.48%to-7.43%).Additionally,the between-imaging agreement(CVI-OCTA versus CVI-OCT)was poor for both devices(Triton,MD,6.05%to 12.68%;VG200I,MD,6.67%to 12.09%).CONCLUSION:Both OCT devices and the two analytical methods demonstrate good stability.The inter-device consistency of CVI-OCT is good,while the inter-device consistency of CVI-OCTA and the consistency between the two analytical methods in the same device are both poor.
文摘The Chinese Journal of Natural Medicines(CJNM,ISSN 2095-6975),founded in 2003 and sponsored by China Pharmaceutical University,is a peer-reviewed journal published monthly in print by Science Press and online by Elsevier.CJNM is currently indexed in Science Citation Index Expanded(SCIE),MEDLINE,BIOSIS Previews,BIOSIS Toxicology,CAB Abstracts.
基金the financial support provided by UMS Great(GUG0670-1/2024),which played a crucial role in the completion of this studyAdditionally,we would like to express our sincere appreciation for the financial assistance and scholarships generously offered by the University of Malaysia Sabah(UMS)throughout the Ministry of Higher Education Malaysia(KPT)throughout the research period.These contributions were invaluable in facilitating our research endeavors.
文摘The growing demand for renewable energy has increased the use of wood pellets as a clean and efficient biomass fuel.This study aims to evaluate the physical properties of wood pellets produced from Acacia hybrid(AC)veneer waste and Pine wood(PW)waste mixed with varying ratios.The objectives are to investigate the effect of different blend ratios ofAcacia hybrid veneer waste and pine wood waste on the physical properties,specificallymoisture content,density,and pellet durability index(PDI)of wood pellets,and to identify the optimal ratio that yields the most desirable pellet quality.The wood pellets were produced by blending Acacia hybrid veneer waste and Pine wood waste(AC:PW)in weight ratios of 100:0,75:25,50:50,25:75,and 0:100.The materials were dried to 10%–12%moisture before pelletizing using a pellet mill under consistent pressure and temperature.Moisture content(MC),density(ρ)and pellet durability index(PDI)were measured following the International Organization for Standardization(ISO).The study found that blending Acacia hybrid veneer waste with Pine wood waste significantly improved pellet density and durability compared to the control.The moisture was lowest in pellets with 50:50 and 25:75 blends,indicating better drying and stability.The blend 50:50 achieves the highest density,and for pellet durability index,the best blend is 25:75,suggesting improved resistance to breakage.Overall,the 50:50 and 25:75 ratios produced pellet with the most desirable combination of low moisture,high density,high durability and the blend meets key ISO 17225 and ENplus quality standards for industrial wood pellet.
