本文根据目前OMA(Open Mobile Alliance,开放移动联盟)对群组,Presence及消息类业务的协议规范,介绍了OMA IMPS体系结构、CSP协议、以及消息封装格式。其中重点对SMS消息封装进行了介绍和研究,提出了基于OMA IMPS协议SMS消息封装的移动...本文根据目前OMA(Open Mobile Alliance,开放移动联盟)对群组,Presence及消息类业务的协议规范,介绍了OMA IMPS体系结构、CSP协议、以及消息封装格式。其中重点对SMS消息封装进行了介绍和研究,提出了基于OMA IMPS协议SMS消息封装的移动终端即时通讯设计方案,并对其可行性进行了评估。展开更多
The kinetics of interracial processes of CdSe thin film electrode before and after sur- face modification of 1,1'-di linolene ferrocenyl L-B films have been studied in K_4Fe(CN)_6 solution by Intensity Modulated P...The kinetics of interracial processes of CdSe thin film electrode before and after sur- face modification of 1,1'-di linolene ferrocenyl L-B films have been studied in K_4Fe(CN)_6 solution by Intensity Modulated Photocurrent Spectroscopy(IMPS).Potential dependence of surface state relaxation time(T_s),steady state photocurrent(I_s),collection coefficient of minority carriers(G_o), rate constant of photocorrosion(K_(cr)),and density of surface state(N_(ss))were determined in terms of frequency response analysis of IMPS plots.展开更多
IMPS（Instant Message and Presence Service）系统是独立于移动通信网络的一个业务处理系统．主要完成即时消息的发送、转寄／拒绝，Presence的订阅、获取、更改．联系人列表和属性列表的控制，组的创建、管理以及内容共享等功能。即...IMPS（Instant Message and Presence Service）系统是独立于移动通信网络的一个业务处理系统．主要完成即时消息的发送、转寄／拒绝，Presence的订阅、获取、更改．联系人列表和属性列表的控制，组的创建、管理以及内容共享等功能。即时消息的发送内容不但可以是文本，还可以是多媒体消息、电子名片、电子日历以及其他MIME类型的多种格式的内容。它涵盖了终端到终端、终端到增值应用、增值应用到终端的即时消息通信。展开更多
The photodegradation reaction rate of CHCl 3 in TiO 2 particulate suspension was improved significantly by HCl-treatment. The effect of HCl-treatment on the photocatalytic activity of TiO 2 was studied in a PEC cel...The photodegradation reaction rate of CHCl 3 in TiO 2 particulate suspension was improved significantly by HCl-treatment. The effect of HCl-treatment on the photocatalytic activity of TiO 2 was studied in a PEC cell by using Intensity-Modulated Photocurrent Spectroscopy (IMPS). The magnitude of photocurrent response and the characteristic frequencies of the upper and lower semicircles in the complex plane of IMPS response were analyzed, and the cathodic and anodic reaction processes of photogenerated holes and electrons were discussed. The increases in the cathodic and anodic photocurrent response and in the time constants of both cathodic and anodic reaction processes indicate that HCl-treatment leads to the improvement of the photocatalytic activity of TiO 2 and a change of the photocatalytic kinetic mechanism.展开更多
The development of deep reservoirs is an emerging topic in the energy industry.This paper analyzes the challenges in simulations of flow and transport in deep reservoirs and introduces models and algorithms aimed at r...The development of deep reservoirs is an emerging topic in the energy industry.This paper analyzes the challenges in simulations of flow and transport in deep reservoirs and introduces models and algorithms aimed at resolving these challenges.A fast,accurate,and robust phase equilibrium model is developed with the aid of deep learning algorithms to accelerate the thermodynamic analysis of deep reservoir fluids.A pixel-free search algorithm is developed to generate a pore-network model that describes pore connectivity and porous media fluidity.A fully conservative Implicit Pressure Explicit Saturation algorithm is developed to simulate the Darcy-scale two-phase flow while achieving a reliable result for production evaluation.Numerical examples are presented to validate the performance of the developed models and algorithms.This paper also presents suggestions for future studies on deep reservoirs to achieve both scientific and engineering progress.展开更多
通过强度调制光电流谱(IMPS)和强度调制光电压谱(IMVS)技术研究在光电分解水制氢体系中碳点光阳极与KOH电解液界面的动力学行为。结果表明,光强在30–90 m W·cm^(-2)范围内,界面的电子传输时间(τ_d)、电子寿命(τ_n)、电子扩散系...通过强度调制光电流谱(IMPS)和强度调制光电压谱(IMVS)技术研究在光电分解水制氢体系中碳点光阳极与KOH电解液界面的动力学行为。结果表明,光强在30–90 m W·cm^(-2)范围内,界面的电子传输时间(τ_d)、电子寿命(τ_n)、电子扩散系数(D_n)、电子扩散长度(L_n)均没有变化;当光强增加到110和130 m W·cm^(-2)时,τ_d和τ_n延长,而D_n减小。实验表明,不同于Ti O_2/电解液等界面,碳点光电极/电解液界面中碳点电极存在的缺陷少,因此电子主要以无陷阱限制扩散方式传输为主。且在30–130 m W·cm^(-2)的光强范围内,与τ_d和τ_n相关的载流子收集效率(η_(cc))相近。展开更多
BACKGROUND Differential diagnosis among atypical hyperplasia(AH)(including reparative hyperplasia and intestinal metaplasia),low-grade dysplasia(LGD),high-grade dysplasia(HGD),and adenocarcinoma(AC)in gastric mucosal ...BACKGROUND Differential diagnosis among atypical hyperplasia(AH)(including reparative hyperplasia and intestinal metaplasia),low-grade dysplasia(LGD),high-grade dysplasia(HGD),and adenocarcinoma(AC)in gastric mucosal biopsies is challenging due to histomorphological overlaps,variability in pathological diagnosis consistency,and limited reproducibility.AIM To evaluate the diagnostic utility of P53,Ki67,P504S,and IMP3 in gastric cancer and its precancerous lesions,focusing on their effectiveness in distinguishing AH,LGD,HGD,and AC.METHODS From January 2018 to September 2020,a total of 185 gastric mucosal biopsy specimens were analyzed according to the pathological diagnostic criteria outlined in the World Health Organization Classification of Digestive System Tumors(2019).The specimens were categorized into four groups:AH,LGD,HGD,and AC.Immunohistochemistry was employed to assess the expression status of P53,Ki67,P504S,and IMP3.Intergroup comparisons were performed using theχ^(2)test or Fisher's exact probability test to compare the differences in immunohistochemical markers across the distinct lesion groups.RESULTS The expression rate of P504S was highest in the LGD group(53.3%,16/30),while IMP3 expression was highest in the AC group(41.9%,26/62),followed by the HGD group(33.3%).Significant differences in P504S and IMP3 expression levels were observed among the four lesion groups(P<0.001).Pairwise comparisons revealed statistically significant differences in P504S expression between the AH group and the LGD,HGD,and AC groups(P<0.001),as well as significant variations in IMP3 expression between the AH group and the HGD and AC groups,and between the LGD group and the HGD and AC groups(P<0.001).Additionally,significant correlations were found between P504S and the polarity expression pattern of Ki67,and between IMP3 and the mutation expression pattern of P53(P<0.001).The combined detection of P504S with Ki67 and IMP3 with P53 increased the diagnostic sensitivity for LGD and HGD/AC,respectively.CONCLUSION P504S is highly expressed in LGD and is associated with the Ki67“polarity”expression pattern.IMP3 is highly expressed in HGD/AC and is correlated with the P53 mutation expression pattern.The combined detection of P504S with Ki67 and IMP3 with P53 increased the diagnostic sensitivity for LGD and HGD/AC,respectively.The rational use of P504S,Ki67,IMP3,and p53 can help distinguish gastric cancer and precancerous lesions,improving the early cancer diagnosis rate.展开更多
RNA contains diverse post-transcriptional modifications,and its catabolic breakdown yields numerous modified nucleosides requiring correct processing,but the mechanisms remain unknown.Here,we demonstrate that three RN...RNA contains diverse post-transcriptional modifications,and its catabolic breakdown yields numerous modified nucleosides requiring correct processing,but the mechanisms remain unknown.Here,we demonstrate that three RNA-derived modified adenosines,N6-methyladenosine(m6A),N6,N6-dimethyladenosine(m6,6A),and N6-isopentenyladenosine(i6A),are sequentially metabolized into inosine monophosphate(IMP)to mitigate their intrinsic cytotoxicity.展开更多
文摘本文根据目前OMA(Open Mobile Alliance,开放移动联盟)对群组,Presence及消息类业务的协议规范,介绍了OMA IMPS体系结构、CSP协议、以及消息封装格式。其中重点对SMS消息封装进行了介绍和研究,提出了基于OMA IMPS协议SMS消息封装的移动终端即时通讯设计方案,并对其可行性进行了评估。
基金This work was supported by the National Natural Science Foundation of China
文摘The kinetics of interracial processes of CdSe thin film electrode before and after sur- face modification of 1,1'-di linolene ferrocenyl L-B films have been studied in K_4Fe(CN)_6 solution by Intensity Modulated Photocurrent Spectroscopy(IMPS).Potential dependence of surface state relaxation time(T_s),steady state photocurrent(I_s),collection coefficient of minority carriers(G_o), rate constant of photocorrosion(K_(cr)),and density of surface state(N_(ss))were determined in terms of frequency response analysis of IMPS plots.
文摘IMPS（Instant Message and Presence Service）系统是独立于移动通信网络的一个业务处理系统．主要完成即时消息的发送、转寄／拒绝，Presence的订阅、获取、更改．联系人列表和属性列表的控制，组的创建、管理以及内容共享等功能。即时消息的发送内容不但可以是文本，还可以是多媒体消息、电子名片、电子日历以及其他MIME类型的多种格式的内容。它涵盖了终端到终端、终端到增值应用、增值应用到终端的即时消息通信。
基金ProjectsupportedbytheNationalNaturalScienceFoundationofChina (No .2 98730 5 7) ,NationalResearchFundforFoundamentalKeyProject (No .G2 0 0 0 0 2 82 0 5 )andtheInnovativeFoundationofChineseAcademyofSciences (No .KGCX2 30 3 0 2)
文摘The photodegradation reaction rate of CHCl 3 in TiO 2 particulate suspension was improved significantly by HCl-treatment. The effect of HCl-treatment on the photocatalytic activity of TiO 2 was studied in a PEC cell by using Intensity-Modulated Photocurrent Spectroscopy (IMPS). The magnitude of photocurrent response and the characteristic frequencies of the upper and lower semicircles in the complex plane of IMPS response were analyzed, and the cathodic and anodic reaction processes of photogenerated holes and electrons were discussed. The increases in the cathodic and anodic photocurrent response and in the time constants of both cathodic and anodic reaction processes indicate that HCl-treatment leads to the improvement of the photocatalytic activity of TiO 2 and a change of the photocatalytic kinetic mechanism.
基金King Abdullah University of Science and Technology,Grant/Award Numbers:BAS/1/1351-01,URF/1/5028-01National Natural Science Foundation of China,Grant/Award Number:51936001。
文摘The development of deep reservoirs is an emerging topic in the energy industry.This paper analyzes the challenges in simulations of flow and transport in deep reservoirs and introduces models and algorithms aimed at resolving these challenges.A fast,accurate,and robust phase equilibrium model is developed with the aid of deep learning algorithms to accelerate the thermodynamic analysis of deep reservoir fluids.A pixel-free search algorithm is developed to generate a pore-network model that describes pore connectivity and porous media fluidity.A fully conservative Implicit Pressure Explicit Saturation algorithm is developed to simulate the Darcy-scale two-phase flow while achieving a reliable result for production evaluation.Numerical examples are presented to validate the performance of the developed models and algorithms.This paper also presents suggestions for future studies on deep reservoirs to achieve both scientific and engineering progress.
文摘通过强度调制光电流谱(IMPS)和强度调制光电压谱(IMVS)技术研究在光电分解水制氢体系中碳点光阳极与KOH电解液界面的动力学行为。结果表明,光强在30–90 m W·cm^(-2)范围内,界面的电子传输时间(τ_d)、电子寿命(τ_n)、电子扩散系数(D_n)、电子扩散长度(L_n)均没有变化;当光强增加到110和130 m W·cm^(-2)时,τ_d和τ_n延长,而D_n减小。实验表明,不同于Ti O_2/电解液等界面,碳点光电极/电解液界面中碳点电极存在的缺陷少,因此电子主要以无陷阱限制扩散方式传输为主。且在30–130 m W·cm^(-2)的光强范围内,与τ_d和τ_n相关的载流子收集效率(η_(cc))相近。
基金Supported by The Science and Technology Research Project of Anyang,No.2022C01SF074。
文摘BACKGROUND Differential diagnosis among atypical hyperplasia(AH)(including reparative hyperplasia and intestinal metaplasia),low-grade dysplasia(LGD),high-grade dysplasia(HGD),and adenocarcinoma(AC)in gastric mucosal biopsies is challenging due to histomorphological overlaps,variability in pathological diagnosis consistency,and limited reproducibility.AIM To evaluate the diagnostic utility of P53,Ki67,P504S,and IMP3 in gastric cancer and its precancerous lesions,focusing on their effectiveness in distinguishing AH,LGD,HGD,and AC.METHODS From January 2018 to September 2020,a total of 185 gastric mucosal biopsy specimens were analyzed according to the pathological diagnostic criteria outlined in the World Health Organization Classification of Digestive System Tumors(2019).The specimens were categorized into four groups:AH,LGD,HGD,and AC.Immunohistochemistry was employed to assess the expression status of P53,Ki67,P504S,and IMP3.Intergroup comparisons were performed using theχ^(2)test or Fisher's exact probability test to compare the differences in immunohistochemical markers across the distinct lesion groups.RESULTS The expression rate of P504S was highest in the LGD group(53.3%,16/30),while IMP3 expression was highest in the AC group(41.9%,26/62),followed by the HGD group(33.3%).Significant differences in P504S and IMP3 expression levels were observed among the four lesion groups(P<0.001).Pairwise comparisons revealed statistically significant differences in P504S expression between the AH group and the LGD,HGD,and AC groups(P<0.001),as well as significant variations in IMP3 expression between the AH group and the HGD and AC groups,and between the LGD group and the HGD and AC groups(P<0.001).Additionally,significant correlations were found between P504S and the polarity expression pattern of Ki67,and between IMP3 and the mutation expression pattern of P53(P<0.001).The combined detection of P504S with Ki67 and IMP3 with P53 increased the diagnostic sensitivity for LGD and HGD/AC,respectively.CONCLUSION P504S is highly expressed in LGD and is associated with the Ki67“polarity”expression pattern.IMP3 is highly expressed in HGD/AC and is correlated with the P53 mutation expression pattern.The combined detection of P504S with Ki67 and IMP3 with P53 increased the diagnostic sensitivity for LGD and HGD/AC,respectively.The rational use of P504S,Ki67,IMP3,and p53 can help distinguish gastric cancer and precancerous lesions,improving the early cancer diagnosis rate.
文摘RNA contains diverse post-transcriptional modifications,and its catabolic breakdown yields numerous modified nucleosides requiring correct processing,but the mechanisms remain unknown.Here,we demonstrate that three RNA-derived modified adenosines,N6-methyladenosine(m6A),N6,N6-dimethyladenosine(m6,6A),and N6-isopentenyladenosine(i6A),are sequentially metabolized into inosine monophosphate(IMP)to mitigate their intrinsic cytotoxicity.
