A new IL-supported diol, 1-（2,3-dihydroxypropyl）-3-methylimidazolium hexafluorophosphate has been synthesized and characterized by Fr-IR, ^1H NMR, ^13C NMR and MS （ESI）. Its physical properties such as freezing po...A new IL-supported diol, 1-（2,3-dihydroxypropyl）-3-methylimidazolium hexafluorophosphate has been synthesized and characterized by Fr-IR, ^1H NMR, ^13C NMR and MS （ESI）. Its physical properties such as freezing point, solubility and specific gravity and thermal stability were determined. Synthetic utilities of the resultant diol as a protecting group for aldehydes were also investigated.展开更多
The synthesis of polyurethanes(PUs)from the reaction of low molecular weight poly(ethylene carbonate)diol(PECD)is rarely investigated.This work reports a novel PU with excellent mechanical properties from the solution...The synthesis of polyurethanes(PUs)from the reaction of low molecular weight poly(ethylene carbonate)diol(PECD)is rarely investigated.This work reports a novel PU with excellent mechanical properties from the solution polymerization of 4,4-diphenylmethane diisocyanate(MDI)with PECD that was derived from the copolymerization of carbon dioxide(CO_(2))and ethylene oxide(EO).The tensile strength,the elongation at break and 300%constant tensile strength of the PECD-PU were up to 66±2 MPa,880%±50%and 13 MPa,respectively,higher than the control PUs from the reaction of MDI with commercial polyethers or polyesters.The PECD-PU with high CO_(2) carbonate content exhibited good solvent resistance and chemical stability.Of importance,the mechanical properties and chemical resistance of PECD-PU were significantly enhanced with the increasing content of CO_(2),i.e.,the carbonate unit in PECD.This work provides comprehensive properties of PECD-derived PUs,indicating that PECD is a competitive precursor for the preparation of PU and has broad application prospects.展开更多
To develop well defined in vitro cell system to test cytotoxicity of a number of model toxins, genetically engineered V79 Chinese hamster fibroblasts expressing isoenzymes of cytochrome P4501A1 XEM2 cells and V79 ce...To develop well defined in vitro cell system to test cytotoxicity of a number of model toxins, genetically engineered V79 Chinese hamster fibroblasts expressing isoenzymes of cytochrome P4501A1 XEM2 cells and V79 cells (parental), which lack cytochrome P450 enzyme activities, were used as controls. The cytotoxic effect of trans 7,8 dihydrbenzo(a)pyrene (BP 7,8 diol) on the parental cells V79 and V79 derived XEM2 cells were evaluated by two methods for cell viability. The data obtained expressed that BP 7,8 diol ranging from 1.0 μmol·L 1 to 5.0 μmol·L 1 in concentrations incubated for 24 h showed a strong cytotoxic effect in XEM2 cells (expressing rat cytochrome P4501A1) in a concentration dependent manner. Time dependent decrease for survival of XEM2 cells was also observed at 2.5 μmol·L 1 concentration. Likewise, BP 7,8 diol did not alter the survival of the parental cells V79 under the same condition. This study also showed that α naphthoflavone (αNF), a well known inhibitor of cytochrome P4501A1 might alter BP 7,8 diol induced cytotoxicity in the XEM2 cells. Our results suggested that cytochrome P4501A1 is responsible for BP 7, 8 diol induced cytotoxicity.展开更多
A novel and facile method toward a series of yellow water-borne polyurethane was developed by using an intrinsically colored diol in this paper.The yellow aqueous dispersion PCLD-HENA-PU was synthesized based on isoph...A novel and facile method toward a series of yellow water-borne polyurethane was developed by using an intrinsically colored diol in this paper.The yellow aqueous dispersion PCLD-HENA-PU was synthesized based on isophorone diisocyanate(IPDI), polycaprolactonediol(PCLD) and 2,2-dimethylol propionic acid(DMPA) using a yellow diol N,N-bis(2-hydroxyethyl)-4-nitroaniline (HENA) as a chain extender.Due to the complete reaction of OH group in colorant HENA with NCO group in diisocyanate,a series of stable yellow p...展开更多
Asymmetric reduction of ct-hydroxy aromatic ketones was carded out by using carrot enzymes system, yielding corresponding chiral vicinal diols with special functional groups. The optimum reaction conditions were obtai...Asymmetric reduction of ct-hydroxy aromatic ketones was carded out by using carrot enzymes system, yielding corresponding chiral vicinal diols with special functional groups. The optimum reaction conditions were obtained after investigation of various influencing factors. Chiral aryl vicinal diols were produced with good yields and excellent enantiomeric excesses under appropriate conditions. Meanwhile, the steric factors and electronic effects of the substituents on the aromatic ring were shown to have an interesting influence on both yield and enantioselectivity.展开更多
Ni/Al_2O_3-SiO_2 catalysts were synthesized via one-step method employing SiO_2 as an additive for the selective hydrogenation of butyne-1,4-diol(B_3D) to butane-1,4-diol(B1D). The prepared catalysts were evaluated by...Ni/Al_2O_3-SiO_2 catalysts were synthesized via one-step method employing SiO_2 as an additive for the selective hydrogenation of butyne-1,4-diol(B_3D) to butane-1,4-diol(B1D). The prepared catalysts were evaluated by a series of characterization techniques including BET, XRD, SEM, EDX-mapping, TEM, H_2-TPR, XPS, NH_3-TPD and Py-FTIR. Compared to Ni/Al_2O_3 catalyst, the SiO_2-doped samples exhibited better B_3D conversion. SiO_2 could help to form a strong interaction between NiO with the support, which inhibited Ni agglomeration at high temperature, improved the Ni dispersion, and enhanced the hydrogenation activity. B_1D selectivity was mainly influenced by the quantity of Lewis acid sites in addition to the Ni dispersion. The catalyst with a silica loading of 6.4% demonstrated an excellent selectivity of 75.18%(by 13% higher than the contrastive Ni/Al_2O_3 catalyst), which was attributed to the larger amount of Lewis acid sites and the moderate interaction between NiO with the support, which could facilitate the nickel dispersion on a preferable surface area of 176.3 m^2/g of support.展开更多
The title compound (C29H50O2, Mr = 430.69) was isolated from the algae Halimeda xishaensis collected from the South China Sea. Its crystal structure was determined by single-crystal X-ray diffraction for the first tim...The title compound (C29H50O2, Mr = 430.69) was isolated from the algae Halimeda xishaensis collected from the South China Sea. Its crystal structure was determined by single-crystal X-ray diffraction for the first time. The crystal belongs to orthorhombic, space group P212121 with a = 8.1560(13), b = 10.7861(18), c = 29.973(5) ? V = 2636.8(8) 3, Z = 4, Dc = 1.085 g/cm3, F(000) = 960, (Mo-K? = 4.533 mm-1, ?= 0.71073 ? S = 1.061, (?max = 0.382 and (?min = 0.244 e/?. The structure was refined to R = 0.0561 and wR = 0.1553 for 2711 observed reflections with I > 2(I). X-ray diffraction analysis reveals that the title compound has two ?OH groups, and the side chain is saturated. There exist two intermolecular hydrogen bonds between three molecules.展开更多
The effect of 2-butyne-1, 4-diol （BD） on the deposition behavior of the Co-Ni alloy was investigated by linear sweep voltammetry. The results showed that BD could prevent the deposition of the Co-Ni alloy. The effec...The effect of 2-butyne-1, 4-diol （BD） on the deposition behavior of the Co-Ni alloy was investigated by linear sweep voltammetry. The results showed that BD could prevent the deposition of the Co-Ni alloy. The effect of BD concentration in the sulfate plating bath, on the structure of the Co-Ni deposit was studied by energy dispersive x-ray spectroscopy, scanning electron microscope, and X-ray diffraction, respectively. As a result, BD could smoothen the deposit surface and decrease the diameter of the grain, but too much of BD was not good for the size of the grain. In general, a hexagonal close-packed （hcp） phase of the Co-Ni alloy, with a preferentially oriented （110） plane, was prepared by electrodeposition in the presence of BD. The Co-Ni alloy as a catalyst for the electro-oxidation of ethanol in alkaline medium was investigated by cyclic voltammetry. The deposit plated from the bath containing BD possessed better electro-oxidation of ethanol performance compared with that of the deposit plated from only the sulfate plating bath, but too much of BD was not beneficial for catalytic activity. The Co-Ni film was suitable as a magnetic recording material.展开更多
A new 3-（3,4-methylenedioxyphenyl）-propane-1,2-diol glycoside,named cinnamomdiol A（1）,together with two known compounds,3-（3,4-methylenedioxyphenyl）-propane-1,2-diol（2） and taxifolin（3）,was isolated from the...A new 3-（3,4-methylenedioxyphenyl）-propane-1,2-diol glycoside,named cinnamomdiol A（1）,together with two known compounds,3-（3,4-methylenedioxyphenyl）-propane-1,2-diol（2） and taxifolin（3）,was isolated from the roots of Cinnamomum camphora.Their structures were determined on the basis of spectroscopic evidences.Compounds 2 and 3 were isolated from the title plant for the first time.展开更多
A series of novel enantiomerically pure diols were synthesized from D-erythorbic acid in three steps, and the absolute configuration of one of them 4a has been confirmed by X-ray analysis.
Interaction between chiral diols BDPDD, DMBDPD and BINOL with prochiral compounds was examined and some new supramolecular complexes were prepared. It was found that these chiral hosts could include prochiral vips,...Interaction between chiral diols BDPDD, DMBDPD and BINOL with prochiral compounds was examined and some new supramolecular complexes were prepared. It was found that these chiral hosts could include prochiral vips, a, b-unsaturated compounds or piper- azinedione derivatives to give inclusion crystals in different molar ratio. Formations of these supramolecular complexes were characterized by the data of IR and 1H NMR spectra.展开更多
1,3-Propanediol, 1,4-butanediol or 1,5-pentanediol reacts with magnesium to form corresponding magnesium alkoxides, which elindnate water with the formation of cyclic ethers and, respectively, allyl alcohol, 3-buten-1...1,3-Propanediol, 1,4-butanediol or 1,5-pentanediol reacts with magnesium to form corresponding magnesium alkoxides, which elindnate water with the formation of cyclic ethers and, respectively, allyl alcohol, 3-buten-1-ol and 4-penten-1-ol.展开更多
Six new polyesters 7a-f were synthesized through the solution polycondensation reaction of diacid chloride 5 with six aromatic diols 6a-f in N,N-dimethyl acetamide(DMAc) as solvent in the presence of pyridine as base....Six new polyesters 7a-f were synthesized through the solution polycondensation reaction of diacid chloride 5 with six aromatic diols 6a-f in N,N-dimethyl acetamide(DMAc) as solvent in the presence of pyridine as base.The polycondensation reaction produced a series of novel polyester containing pyridyl moiety in the main chain in high yields with inherent viscosities between 0.35 and 0.54 dL/g.The resulted polymers were fully characterized by means of FT-IR spectroscopy,elemental analyses,inherent viscosity ...展开更多
基金the National Natural Science Foundation of China(No.20533010,20673039)the Science&Technology Commission of Shanghai Municipality(No.06JC14023)for financial support.
文摘A new IL-supported diol, 1-（2,3-dihydroxypropyl）-3-methylimidazolium hexafluorophosphate has been synthesized and characterized by Fr-IR, ^1H NMR, ^13C NMR and MS （ESI）. Its physical properties such as freezing point, solubility and specific gravity and thermal stability were determined. Synthetic utilities of the resultant diol as a protecting group for aldehydes were also investigated.
基金financially supported by the Maoming Science and Technology Bureau(No.2022DZXHT007)。
文摘The synthesis of polyurethanes(PUs)from the reaction of low molecular weight poly(ethylene carbonate)diol(PECD)is rarely investigated.This work reports a novel PU with excellent mechanical properties from the solution polymerization of 4,4-diphenylmethane diisocyanate(MDI)with PECD that was derived from the copolymerization of carbon dioxide(CO_(2))and ethylene oxide(EO).The tensile strength,the elongation at break and 300%constant tensile strength of the PECD-PU were up to 66±2 MPa,880%±50%and 13 MPa,respectively,higher than the control PUs from the reaction of MDI with commercial polyethers or polyesters.The PECD-PU with high CO_(2) carbonate content exhibited good solvent resistance and chemical stability.Of importance,the mechanical properties and chemical resistance of PECD-PU were significantly enhanced with the increasing content of CO_(2),i.e.,the carbonate unit in PECD.This work provides comprehensive properties of PECD-derived PUs,indicating that PECD is a competitive precursor for the preparation of PU and has broad application prospects.
文摘To develop well defined in vitro cell system to test cytotoxicity of a number of model toxins, genetically engineered V79 Chinese hamster fibroblasts expressing isoenzymes of cytochrome P4501A1 XEM2 cells and V79 cells (parental), which lack cytochrome P450 enzyme activities, were used as controls. The cytotoxic effect of trans 7,8 dihydrbenzo(a)pyrene (BP 7,8 diol) on the parental cells V79 and V79 derived XEM2 cells were evaluated by two methods for cell viability. The data obtained expressed that BP 7,8 diol ranging from 1.0 μmol·L 1 to 5.0 μmol·L 1 in concentrations incubated for 24 h showed a strong cytotoxic effect in XEM2 cells (expressing rat cytochrome P4501A1) in a concentration dependent manner. Time dependent decrease for survival of XEM2 cells was also observed at 2.5 μmol·L 1 concentration. Likewise, BP 7,8 diol did not alter the survival of the parental cells V79 under the same condition. This study also showed that α naphthoflavone (αNF), a well known inhibitor of cytochrome P4501A1 might alter BP 7,8 diol induced cytotoxicity in the XEM2 cells. Our results suggested that cytochrome P4501A1 is responsible for BP 7, 8 diol induced cytotoxicity.
基金the National Natural Science Foundation of China(No.50273035)
文摘A novel and facile method toward a series of yellow water-borne polyurethane was developed by using an intrinsically colored diol in this paper.The yellow aqueous dispersion PCLD-HENA-PU was synthesized based on isophorone diisocyanate(IPDI), polycaprolactonediol(PCLD) and 2,2-dimethylol propionic acid(DMPA) using a yellow diol N,N-bis(2-hydroxyethyl)-4-nitroaniline (HENA) as a chain extender.Due to the complete reaction of OH group in colorant HENA with NCO group in diisocyanate,a series of stable yellow p...
基金supported by the National Natural Science Foundation of China(No.21176203)the National Special Fund for State Key Laboratory of Bioreactor Engineering(No.2060204)the Fundamental Research Funds for the Central Universities(No.JUSRP211A12)
文摘Asymmetric reduction of ct-hydroxy aromatic ketones was carded out by using carrot enzymes system, yielding corresponding chiral vicinal diols with special functional groups. The optimum reaction conditions were obtained after investigation of various influencing factors. Chiral aryl vicinal diols were produced with good yields and excellent enantiomeric excesses under appropriate conditions. Meanwhile, the steric factors and electronic effects of the substituents on the aromatic ring were shown to have an interesting influence on both yield and enantioselectivity.
基金Financial support from the National Natural Science Foundation of China (21163019) is gratefully acknowledged
文摘Ni/Al_2O_3-SiO_2 catalysts were synthesized via one-step method employing SiO_2 as an additive for the selective hydrogenation of butyne-1,4-diol(B_3D) to butane-1,4-diol(B1D). The prepared catalysts were evaluated by a series of characterization techniques including BET, XRD, SEM, EDX-mapping, TEM, H_2-TPR, XPS, NH_3-TPD and Py-FTIR. Compared to Ni/Al_2O_3 catalyst, the SiO_2-doped samples exhibited better B_3D conversion. SiO_2 could help to form a strong interaction between NiO with the support, which inhibited Ni agglomeration at high temperature, improved the Ni dispersion, and enhanced the hydrogenation activity. B_1D selectivity was mainly influenced by the quantity of Lewis acid sites in addition to the Ni dispersion. The catalyst with a silica loading of 6.4% demonstrated an excellent selectivity of 75.18%(by 13% higher than the contrastive Ni/Al_2O_3 catalyst), which was attributed to the larger amount of Lewis acid sites and the moderate interaction between NiO with the support, which could facilitate the nickel dispersion on a preferable surface area of 176.3 m^2/g of support.
基金the 863 National Foundation of China (No. 2001AA628100) National Natural Science Foundation of China (No. 20002001) and Natural Science Foundation of Guangdong Province (No .000720)
文摘The title compound (C29H50O2, Mr = 430.69) was isolated from the algae Halimeda xishaensis collected from the South China Sea. Its crystal structure was determined by single-crystal X-ray diffraction for the first time. The crystal belongs to orthorhombic, space group P212121 with a = 8.1560(13), b = 10.7861(18), c = 29.973(5) ? V = 2636.8(8) 3, Z = 4, Dc = 1.085 g/cm3, F(000) = 960, (Mo-K? = 4.533 mm-1, ?= 0.71073 ? S = 1.061, (?max = 0.382 and (?min = 0.244 e/?. The structure was refined to R = 0.0561 and wR = 0.1553 for 2711 observed reflections with I > 2(I). X-ray diffraction analysis reveals that the title compound has two ?OH groups, and the side chain is saturated. There exist two intermolecular hydrogen bonds between three molecules.
基金supported by the Natural Science Foundation of Fujian Province,China(Grant No.2006J0440).
文摘The effect of 2-butyne-1, 4-diol （BD） on the deposition behavior of the Co-Ni alloy was investigated by linear sweep voltammetry. The results showed that BD could prevent the deposition of the Co-Ni alloy. The effect of BD concentration in the sulfate plating bath, on the structure of the Co-Ni deposit was studied by energy dispersive x-ray spectroscopy, scanning electron microscope, and X-ray diffraction, respectively. As a result, BD could smoothen the deposit surface and decrease the diameter of the grain, but too much of BD was not good for the size of the grain. In general, a hexagonal close-packed （hcp） phase of the Co-Ni alloy, with a preferentially oriented （110） plane, was prepared by electrodeposition in the presence of BD. The Co-Ni alloy as a catalyst for the electro-oxidation of ethanol in alkaline medium was investigated by cyclic voltammetry. The deposit plated from the bath containing BD possessed better electro-oxidation of ethanol performance compared with that of the deposit plated from only the sulfate plating bath, but too much of BD was not beneficial for catalytic activity. The Co-Ni film was suitable as a magnetic recording material.
文摘A new 3-（3,4-methylenedioxyphenyl）-propane-1,2-diol glycoside,named cinnamomdiol A（1）,together with two known compounds,3-（3,4-methylenedioxyphenyl）-propane-1,2-diol（2） and taxifolin（3）,was isolated from the roots of Cinnamomum camphora.Their structures were determined on the basis of spectroscopic evidences.Compounds 2 and 3 were isolated from the title plant for the first time.
基金the National Natural Science Foundation of China for the project support (No. 29972021 )
文摘A series of novel enantiomerically pure diols were synthesized from D-erythorbic acid in three steps, and the absolute configuration of one of them 4a has been confirmed by X-ray analysis.
基金This work was supported by the National Natural Science Foundation of China (Project 29972033) and the Key Science Research Foundation of Hubei Province of China (Project 98IP1305).
文摘Interaction between chiral diols BDPDD, DMBDPD and BINOL with prochiral compounds was examined and some new supramolecular complexes were prepared. It was found that these chiral hosts could include prochiral vips, a, b-unsaturated compounds or piper- azinedione derivatives to give inclusion crystals in different molar ratio. Formations of these supramolecular complexes were characterized by the data of IR and 1H NMR spectra.
文摘1,3-Propanediol, 1,4-butanediol or 1,5-pentanediol reacts with magnesium to form corresponding magnesium alkoxides, which elindnate water with the formation of cyclic ethers and, respectively, allyl alcohol, 3-buten-1-ol and 4-penten-1-ol.
文摘Six new polyesters 7a-f were synthesized through the solution polycondensation reaction of diacid chloride 5 with six aromatic diols 6a-f in N,N-dimethyl acetamide(DMAc) as solvent in the presence of pyridine as base.The polycondensation reaction produced a series of novel polyester containing pyridyl moiety in the main chain in high yields with inherent viscosities between 0.35 and 0.54 dL/g.The resulted polymers were fully characterized by means of FT-IR spectroscopy,elemental analyses,inherent viscosity ...
