Pipe-routing for ship is formulated as searching for the near-optimal pipe paths while meeting certain objectives in an environment scattered with obstacles. Due to the complex construction in layout space, the great ...Pipe-routing for ship is formulated as searching for the near-optimal pipe paths while meeting certain objectives in an environment scattered with obstacles. Due to the complex construction in layout space, the great number of pipelines, numerous and diverse design constraints and large amount of obstacles, finding the optimum route of ship pipes is a complicated and time-consuming process. A modified NSGA-II algorithm based approach is proposed to find the near-optimal solution to solve the problem. By simplified equipment models, the layout space is firstly divided into three dimensional （3D） grids to build its mathematical model. In the modified NSGA-II algorithm, the concept of auxiliary point is introduced to improve the search range of maze algorithm （MA） as well as to guarantee the diversity of chromosomes in initial population. Then the fix-length coding mechanism is proposed, Fuzzy set theory is also adopted to select the optimal solution in Pareto solutions. Finally, the effectiveness and efficiency of the proposed approach is demonstrated by the contrast test and simulation. The merit of the proposed algorithm lies in that it can provide more appropriate solutions for the designers while subject certain constrains.展开更多
Side information （SI） is one of the key issues in distributed video coding （DVC） and affects the compression performance of DVC largely. This paper proposes an SI refinement algorithm, in which the Wyner-Ziv （WZ...Side information （SI） is one of the key issues in distributed video coding （DVC） and affects the compression performance of DVC largely. This paper proposes an SI refinement algorithm, in which the Wyner-Ziv （WZ） frame is split into two parts based on checkerboard pattern, and the two parts are encoded independently but decoded sequentially. In the decoding process, the part 1 is first decoded with the initial SI and partially decoded part （PDP） 1 is used to improve the motion vectors （MVs） and SI of both parts. At the next stage, the part 2 is decoded with the improved SI and PDP 2 is used to further refine MVs of the part 2. Then, SI of both parts are further refined. Simulation results show that the proposed algorithm can improve the peak signal to noise ratio （PSNR） by up to 1.43 dB when compared with traditional DVC codec.展开更多
Some specified chips in traditional Manchester-Ⅱencoding/decoding designs are used to guarantee strictly the stability of the input wave,otherwise the capacity of anti-interference and resilience are degraded serious...Some specified chips in traditional Manchester-Ⅱencoding/decoding designs are used to guarantee strictly the stability of the input wave,otherwise the capacity of anti-interference and resilience are degraded seriously.In this paper,a new Manchester-Ⅱencoding/ decoding system is used for nuclear logging by a 7 000 m armoring cable.A thorough hardware wave tracking decoding algorithm is proposed and realized in a FPGA hardware chip.An on-site measurements show that this transmission system can decode correctly in real time,with a bit error rate of better than 10^(-10).展开更多
目的研究中药复方桃红四物汤(Tao Hong Si Wu decoction,THSWD)治疗大脑中动脉闭塞(middle cerebral artery occlusion,MCAO)大鼠长链非编码RNA(long non-coding RNA,lncRNA)的表达,并确定THSWD治疗MCAO大鼠可能的分子机制。方法从对照...目的研究中药复方桃红四物汤(Tao Hong Si Wu decoction,THSWD)治疗大脑中动脉闭塞(middle cerebral artery occlusion,MCAO)大鼠长链非编码RNA(long non-coding RNA,lncRNA)的表达,并确定THSWD治疗MCAO大鼠可能的分子机制。方法从对照组、MCAO组和MCAO+THSWD组各获得3个大脑半球组织。采用RNA测序技术鉴定三组中的lncRNA基因表达。鉴定了THSWD调节的lncRNA基因,然后构建了THSWD调节的lncRNA-mRNA网络。通过MCODE插件鉴定lncRNA-mRNA网络的模块。基因本体(gene ontology,GO)和京都基因与基因组百科全书数据库(kyoto encyclopedia of genes and genomes,KEGG)用于分析富集的生物功能和信号通路。鉴定了THSWD调节的lncRNA的顺式和反式调控基因。采用逆转录实时定量聚合酶链式反应(RT-qPCR)验证lncRNA。分子对接用于验证lncRNA-mRNA网络靶点和通路相关蛋白结合能力。结果在MCAO大鼠中,THSWD共调节了302个lncRNA。生物信息学分析表明,一些核心lncRNA可能在THSWD治疗MCAO大鼠中发挥重要作用,此外,我们进一步发现THSWD可能也通过lncRNA-mRNA网络以及网络富集的补体和凝血级联反应等多通路治疗MCAO大鼠。分子对接结果表明,THSWD活性化合物没食子酸和苦杏仁苷与蛋白质靶点具有一定的结合能力。结论THSWD可以通过调节lncRNA保护MCAO大鼠脑损伤,为THSWD治疗缺血性中风提供了新见解。展开更多
基金Supported by National Nature Science Foundation of China(Grant No:51275340)
文摘Pipe-routing for ship is formulated as searching for the near-optimal pipe paths while meeting certain objectives in an environment scattered with obstacles. Due to the complex construction in layout space, the great number of pipelines, numerous and diverse design constraints and large amount of obstacles, finding the optimum route of ship pipes is a complicated and time-consuming process. A modified NSGA-II algorithm based approach is proposed to find the near-optimal solution to solve the problem. By simplified equipment models, the layout space is firstly divided into three dimensional （3D） grids to build its mathematical model. In the modified NSGA-II algorithm, the concept of auxiliary point is introduced to improve the search range of maze algorithm （MA） as well as to guarantee the diversity of chromosomes in initial population. Then the fix-length coding mechanism is proposed, Fuzzy set theory is also adopted to select the optimal solution in Pareto solutions. Finally, the effectiveness and efficiency of the proposed approach is demonstrated by the contrast test and simulation. The merit of the proposed algorithm lies in that it can provide more appropriate solutions for the designers while subject certain constrains.
基金Supported by the National Natural Science Foundation of China （ No. 60736043, 60672088） and the National Basic Research Program of China （No. 2009CB32005）.
文摘Side information （SI） is one of the key issues in distributed video coding （DVC） and affects the compression performance of DVC largely. This paper proposes an SI refinement algorithm, in which the Wyner-Ziv （WZ） frame is split into two parts based on checkerboard pattern, and the two parts are encoded independently but decoded sequentially. In the decoding process, the part 1 is first decoded with the initial SI and partially decoded part （PDP） 1 is used to improve the motion vectors （MVs） and SI of both parts. At the next stage, the part 2 is decoded with the improved SI and PDP 2 is used to further refine MVs of the part 2. Then, SI of both parts are further refined. Simulation results show that the proposed algorithm can improve the peak signal to noise ratio （PSNR） by up to 1.43 dB when compared with traditional DVC codec.
基金Supported by the China National High Technology Research and Development Program(863 Plans) funding for this project(No,2006AA09A102-02)
文摘Some specified chips in traditional Manchester-Ⅱencoding/decoding designs are used to guarantee strictly the stability of the input wave,otherwise the capacity of anti-interference and resilience are degraded seriously.In this paper,a new Manchester-Ⅱencoding/ decoding system is used for nuclear logging by a 7 000 m armoring cable.A thorough hardware wave tracking decoding algorithm is proposed and realized in a FPGA hardware chip.An on-site measurements show that this transmission system can decode correctly in real time,with a bit error rate of better than 10^(-10).
文摘目的研究中药复方桃红四物汤(Tao Hong Si Wu decoction,THSWD)治疗大脑中动脉闭塞(middle cerebral artery occlusion,MCAO)大鼠长链非编码RNA(long non-coding RNA,lncRNA)的表达,并确定THSWD治疗MCAO大鼠可能的分子机制。方法从对照组、MCAO组和MCAO+THSWD组各获得3个大脑半球组织。采用RNA测序技术鉴定三组中的lncRNA基因表达。鉴定了THSWD调节的lncRNA基因,然后构建了THSWD调节的lncRNA-mRNA网络。通过MCODE插件鉴定lncRNA-mRNA网络的模块。基因本体(gene ontology,GO)和京都基因与基因组百科全书数据库(kyoto encyclopedia of genes and genomes,KEGG)用于分析富集的生物功能和信号通路。鉴定了THSWD调节的lncRNA的顺式和反式调控基因。采用逆转录实时定量聚合酶链式反应(RT-qPCR)验证lncRNA。分子对接用于验证lncRNA-mRNA网络靶点和通路相关蛋白结合能力。结果在MCAO大鼠中,THSWD共调节了302个lncRNA。生物信息学分析表明,一些核心lncRNA可能在THSWD治疗MCAO大鼠中发挥重要作用,此外,我们进一步发现THSWD可能也通过lncRNA-mRNA网络以及网络富集的补体和凝血级联反应等多通路治疗MCAO大鼠。分子对接结果表明,THSWD活性化合物没食子酸和苦杏仁苷与蛋白质靶点具有一定的结合能力。结论THSWD可以通过调节lncRNA保护MCAO大鼠脑损伤,为THSWD治疗缺血性中风提供了新见解。
