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约恩·福瑟《另一个名字:七部曲I-II》的记忆与自我
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作者 武姨虹 孔瑞 《语言与文化研究》 2026年第1期208-211,共4页
2023年诺贝尔文学奖得主约恩·福瑟新近出版的小说《另一个名字:七部曲I-II》的记忆书写不仅是叙事手法,更揭示了自我身份建构主题。本文基于记忆理论,探析“既视”记忆中的自我危机,记忆之场的自我追寻,以及通过自传体记忆建构自... 2023年诺贝尔文学奖得主约恩·福瑟新近出版的小说《另一个名字:七部曲I-II》的记忆书写不仅是叙事手法,更揭示了自我身份建构主题。本文基于记忆理论,探析“既视”记忆中的自我危机,记忆之场的自我追寻,以及通过自传体记忆建构自我。记忆深入人类心灵深处,呈现了自我在非线性时间中的流动与重构,也揭示了人类对存在本质的永恒追问。 展开更多
关键词 约恩·福瑟 《另一个名字:七部曲I-ii 记忆 自我
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基于DNN-NSGA-II的高填方加筋边坡参数优化研究
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作者 查文华 谭雪剑 +3 位作者 许涛 徐源歆 赖斯祾 纪超 《水力发电》 2026年第1期45-51,共7页
以福建某典型高填方加筋边坡为研究对象,提出一种集成深度神经网络(DNN)与非支配排序遗传算法(NSGA-II)的智能化优化设计方法,用于实现高填方加筋边坡支护设计的多目标协同优化。首先,通过有限元模拟生成样本数据,构建以关键设计参数为... 以福建某典型高填方加筋边坡为研究对象,提出一种集成深度神经网络(DNN)与非支配排序遗传算法(NSGA-II)的智能化优化设计方法,用于实现高填方加筋边坡支护设计的多目标协同优化。首先,通过有限元模拟生成样本数据,构建以关键设计参数为输入、稳定性响应指标为输出的DNN代理模型;随后,将该代理模型嵌入NSGA-II框架,实现以最小化水平位移、加筋材料用量与最大化安全系数为目标的多目标寻优。通过对Pareto前沿解集的分析与典型方案提取,验证所提方法在兼顾边坡安全性与经济性方面的有效性,可为高填方边坡优化设计提供理论支撑与工程参考。 展开更多
关键词 高填方边坡 加筋设计 多目标优化 深度神经网络 非支配排序遗传算法
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基于Modified Page模型的玉米含水率预测及动力学分析
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作者 齐迹 李健 +4 位作者 窦雪峰 孙旸 胡雅婷 李伟 张芳靖 《吉林农业大学学报》 北大核心 2025年第2期373-378,共6页
为了研究玉米的干燥特性以提高干燥效率,分析了微波功率、装载量、籽粒的初始含水率及初始温度等指标,得到了玉米籽粒干燥特性的变化规律。结果表明:微波干燥功率和温度对玉米籽粒的干燥特性有着很大的影响。使用SPSS运用回归分析和数... 为了研究玉米的干燥特性以提高干燥效率,分析了微波功率、装载量、籽粒的初始含水率及初始温度等指标,得到了玉米籽粒干燥特性的变化规律。结果表明:微波干燥功率和温度对玉米籽粒的干燥特性有着很大的影响。使用SPSS运用回归分析和数值分析方法对玉米微波干燥试验数据与Modified Page模型进行拟合,得到其评价指标R^(2)>0.991 0,χ^(2)<0.053 4,RMES<0.087,并经过验证试验,实测值与模型的预测值具有良好的相关系数(R^(2)>0.99),这表明该模型有利于提高干燥效率,提升玉米含水率的预测精度,以期确保玉米品质和安全。 展开更多
关键词 玉米 modified Page模型 微波干燥 含水率 回归分析
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A^(*)与NSGA-II融合的船舶气象航线多目标规划方法 被引量:1
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作者 李元奎 索基源 +3 位作者 于东冶 张新宇 杨放 杨雪锋 《中国舰船研究》 北大核心 2025年第3期288-295,共8页
[目的]面向我国智能航运和气象导航国产化的发展要求,提出一种基于A^(*)与非支配排序遗传算法(NSGA-II)融合的船舶多目标航线规划方法,以适应复杂多样的远洋航行任务。[方法]通过将A^(*)算法引入至NSGA-II中引导搜索方向加快算法收敛速... [目的]面向我国智能航运和气象导航国产化的发展要求,提出一种基于A^(*)与非支配排序遗传算法(NSGA-II)融合的船舶多目标航线规划方法,以适应复杂多样的远洋航行任务。[方法]通过将A^(*)算法引入至NSGA-II中引导搜索方向加快算法收敛速度,然后通过构建环境数据模型和目标函数,采用跨太平洋航线对模型和算法进行仿真验证。[结果]仿真结果表明:设计的模型和算法可求解得到分布均匀、多样化的Pareto最优航线解集,所有航线均可以顺利躲避大风浪区域,且可根据决策者需求选择船舶最适航线。[结论]所提方法可用于多约束条件下的船舶远洋航线优化,求解符合航次目标的航线,从而降低营运成本、提高航运效率,对船舶气象导航和未来船舶智能航行具有一定的支撑作用。 展开更多
关键词 气象航线 多目标优化 A^(*)算法 NSGA-ii 智能航行 遗传算法
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Effects of Active Modified Atmosphere Packaging on Postharvest Quality of Shiitake Mushrooms (Lentinula edodes) Stored at Cold Storage 被引量:44
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作者 YE Jing-jun LI Jian-rong +3 位作者 HAN Xiao-xiang ZHANG Lei JIANG Tian-jia XIA Miao 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2012年第3期474-482,共9页
The effects of active modified atmosphere packaging (MAP) on the postharvest quality of shiitake mushrooms stored at cold temperature (4°C) were investigated.The gas components were 2% O2 +7% CO2 (MAP1),2%... The effects of active modified atmosphere packaging (MAP) on the postharvest quality of shiitake mushrooms stored at cold temperature (4°C) were investigated.The gas components were 2% O2 +7% CO2 (MAP1),2% O2 +10% CO2 (MAP2) and 2% O2 +13% CO2 (MAP3),respectively.The results showed that active MAP could extend the shelf-life of shiitake mushrooms to 17 d and the concentration of carbon dioxide could influence the postharvest quality of shiitake mushrooms.MAP2 treatment inhibited the increase in respiration rate and malondinaldehyde (MDA) contents,delayed the decrease in firmness,soluble sugar and vitamin C,and obviously reduced the activity of polyphenol oxidase (PPO) and the degree of browning,therefore maintaining better quality. 展开更多
关键词 shiitake mushrooms modified atmosphere package (MAP) postharvest quality
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1例II型糖尿病患者合并血栓性血小板减少性紫癜的护理
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作者 林静 滕晓琼 +2 位作者 彭静 张晨馨 郭君怡 《护理学》 2025年第3期344-349,共6页
目的:总结一例64岁II型糖尿病合并血栓性血小板减少性紫癜患者在院治疗调控血糖期间针对在血浆置换治疗过程中出现感染、内分泌代谢紊乱、出血、气体交换障碍等主要护理问题的护理要点,以期为相似案例提供借鉴。方法:就患者治疗全周期... 目的:总结一例64岁II型糖尿病合并血栓性血小板减少性紫癜患者在院治疗调控血糖期间针对在血浆置换治疗过程中出现感染、内分泌代谢紊乱、出血、气体交换障碍等主要护理问题的护理要点,以期为相似案例提供借鉴。方法:就患者治疗全周期进行管理,以抢救生命、治疗疾病为重点,期间以控制管理基础疾病为基础,包括预防感染、血糖管理、症状护理、血浆置换护理、管道管理、心理护理等方面。结果:连续治疗10 d后患者生命体征暂时能够平稳,病情得到控制。结论:对患者生命治疗周期进行整体管控护理,针对基础慢性疾病合并疑难急症进行科学合理地护理,能迅速保障患者生命安全、提升治疗效率。Objective: To summarize the key points of nursing for a 64-year-old patient with type II diabetes mellitus complicated with thrombotic thrombocytopenic purpura during inpatient treatment for major nursing problems such as infection, endocrine and metabolic disorders, bleeding and gas exchange disorders during plasma exchange treatment, in order to provide reference for similar cases. Methods: The whole cycle of treatment was managed, focusing on life-saving and disease treatment, and the control and management of underlying diseases were the basis, including infection prevention, blood glucose management, symptom nursing, plasmapheresis nursing, pipeline management, and psychological nursing. Results: After 10 days of continuous treatment, the patient’s vital signs were temporarily stable and the condition was controlled. Conclusion: The overall control and nursing of the patient’s life cycle and the scientific and reasonable nursing for the underlying chronic diseases combined with intractable and urgent diseases can quickly ensure the life safety of patients and improve the treatment efficiency. 展开更多
关键词 血栓性血小板减少性紫癜 ii型糖尿病 血浆置换 护理
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Systematic Synthesis on Pathological Models of CCCII and Modified CCCII 被引量:4
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作者 Yong-An Li Yan-Hua Xi +2 位作者 Zhan-Ting Fan Yu-Ye Zhang Ji-Xia Wu 《Journal of Electronic Science and Technology》 CAS CSCD 2018年第2期163-168,共6页
According to the equivalent view for the terminal current-voltage constraint relationship between pathological elements and the various second-generation current-controlled convegors (CCCIIs), four patholo- gical mo... According to the equivalent view for the terminal current-voltage constraint relationship between pathological elements and the various second-generation current-controlled convegors (CCCIIs), four patholo- gical models for the CCCII are first derived by means of the nodal admittance matrix expansion in this paper. Moreover, 48 new pathological models for the modified CCCII are also synthesized. The derived pathological models for the various CCCIIs are expected to be useful in circuit analysis and synthesis. 展开更多
关键词 modified second-generation currentcontrolled conveyor pathological elements secondgeneration current-controlled conveyor systematic synthesis
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Nonlocal symmetry and exact solutions of the(2+1)-dimensional modified Bogoyavlenskii–Schiff equation 被引量:3
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作者 黄丽丽 陈勇 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第6期63-70,共8页
In this paper,the truncated Painlev′e analysis,nonlocal symmetry,Bcklund transformation of the(2+1)-dimensional modified Bogoyavlenskii–Schiff equation are presented.Then the nonlocal symmetry is localized to the... In this paper,the truncated Painlev′e analysis,nonlocal symmetry,Bcklund transformation of the(2+1)-dimensional modified Bogoyavlenskii–Schiff equation are presented.Then the nonlocal symmetry is localized to the corresponding nonlocal group by the prolonged system.In addition,the(2+1)-dimensional modified Bogoyavlenskii–Schiff is proved consistent Riccati expansion(CRE) solvable.As a result,the soliton–cnoidal wave interaction solutions of the equation are explicitly given,which are difficult to find by other traditional methods.Moreover figures are given out to show the properties of the explicit analytic interaction solutions. 展开更多
关键词 (2+1)-dimensional modified Bogoyavlenskii–Schiff equation nonlocal symmetry consistent Riccati expansion soliton–cnoidal wave solution
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Study on the Effect of A Magnetic Field on Pb(II) Removal Using Modified Chitosan 被引量:2
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作者 Lihong Duan Siyuan Guo Jinqing Yang 《Advances in Chemical Engineering and Science》 2012年第1期101-107,共7页
This work examined the removal of Pb(II) using a chitosan derivative (SB, synthesized from benzaldehyde) assisted by a magnetic field. The adsorption capacity for Pb(II) was investigated. It was found that 1) the pH a... This work examined the removal of Pb(II) using a chitosan derivative (SB, synthesized from benzaldehyde) assisted by a magnetic field. The adsorption capacity for Pb(II) was investigated. It was found that 1) the pH and concentration of the ion solution, as well as exposure time and strength of magnetic field, affected the degree of adsorption;and 2) studies of the adsorption isotherms and kinetics of ions onto SB revealed that SB showed enhanced adsorption capacity towards Pb(II) ions in a magnetic field compared with magnetically untreated samples. The Langmuir and Freundlich isotherm were applied to describe the experimental adsorption, and the maximum adsorption capacity of SB for Pb(II) was 2.5040 mg/g, when assisted by a magnetic field of 480 kA/m. 展开更多
关键词 MAGNETIC FIELD CHITOSAN PB(ii) REMOVAL
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Adsorptive Removal of Antimony (III) Using Modified Montmorillonite: A Study on Sorption Kinetics 被引量:2
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作者 Ansar Anjum Monika Datta 《Journal of Analytical Sciences, Methods and Instrumentation》 2012年第3期167-175,共9页
The adsorptive removal of antimony (III) has been successfully obtained on montmorillonite (MMT) and modified MMT from synthetic solution. The adsorption behavior of the modified and unmodified MMT has been investigat... The adsorptive removal of antimony (III) has been successfully obtained on montmorillonite (MMT) and modified MMT from synthetic solution. The adsorption behavior of the modified and unmodified MMT has been investigated as a function of initial concentration of metal ion in the solution, pH of the solution and contact time using a batch extraction process. The optimized process can be applied for the adsorption, detection and estimation of antimony from 0.006 μg/ml (6.0 ppb) to 100.00 μg/ml (100.0 ppm) in aqueous solution. It has been observed that almost 99% of antimony (III) can be successfully extracted from a solution containing 100 μg/ml of the metal ion at pH 6.0 at 25?C ± 2?C. The investigation of the kinetics of sorption of antimony (III) on MMT/modified MMTshows intraparticle diffusion to be the rate limiting step during the initial stages of adsorption followed by chemisorption. 展开更多
关键词 Adsorption ANTIMONY (iiI) MONTMORILLONITE modified MMT
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Synthesis of Magnetically Modified Fe-Al Pillared Bentonite and Heterogeneous Fenton-like Degradation of Orange II 被引量:2
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作者 陈坤 WANG Guanghua +5 位作者 李文兵 WAN Dong HU Qin LU Lulu WEI Xiaobi CHENG Zhengzai 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2015年第2期302-306,共5页
Magnetically modified Fe-Al pillared bentonite(Fe3O4/ Fe-Al-Bent) was prepared via chemical co-precipitation method and characterized by powder X-ray diffraction(XRD), Brunauer-EmmettTeller(BET), Fourier transfo... Magnetically modified Fe-Al pillared bentonite(Fe3O4/ Fe-Al-Bent) was prepared via chemical co-precipitation method and characterized by powder X-ray diffraction(XRD), Brunauer-EmmettTeller(BET), Fourier transform infrared spectroscopy(FTIR) and scanning electron microscopy(SEM). A series of experiments were carried out to investigate the degradation of Orange II by the obtained heterogeneous catalysts in the presence of H2O2. The experimental result indicated that the synthetic materials had a high catalytic activity and good reusability. 展开更多
关键词 Fe3O4 nanoparticles pillared bentonite heterogeneous Fenton-like Orange ii
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基于NSGA-II目标优化的BIM建筑节能效果分析
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作者 潘伟 《建设科技》 2025年第12期56-58,共3页
为客观评价建筑节能效果,确定科学可行的建筑节能优化方法,本文提出集非支配排序遗传算法第二代与BIM技术于一体的建筑节能优化策略。通过对NSGA-II算法的了解,建立建筑节能效果优化模型,阐述模型求解方法。在了解研究方法的基本理论后... 为客观评价建筑节能效果,确定科学可行的建筑节能优化方法,本文提出集非支配排序遗传算法第二代与BIM技术于一体的建筑节能优化策略。通过对NSGA-II算法的了解,建立建筑节能效果优化模型,阐述模型求解方法。在了解研究方法的基本理论后,以某高层住宅建筑为例进行实例研究,构建BIM模型,评价建筑节能优化方法的实施效果。研究表明,建筑节能效果良好,通过节能优化措施的落实,有效降低建筑能源消耗。本文方法为建筑节能优化提供理论参考,根据建筑建设条件和使用条件采取针对性的节能优化策略,促进建筑行业朝着节能环保的方向发展。 展开更多
关键词 NSGA-ii BIM 建筑 节能 效果
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EASTMAN-AQ/Ni(II)MODIFIED ELECTRODE DETECTION OF CARBOHYDRATES AND AMINO ACIDS
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作者 An Hua LIU Er Kang WANG LAboratory of Electroanalytical Chemistry,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun,Jilin 130022 《Chinese Chemical Letters》 SCIE CAS CSCD 1993年第4期347-350,共4页
An Eastman-AQ/Ni(II)chemically modified electrode(CME) produced by“double coating steps”deposition of Eastman-AQ/Ni(II) film and Ni(II)-coating crystalline species onto glassy carbon instead of metallic nickel elect... An Eastman-AQ/Ni(II)chemically modified electrode(CME) produced by“double coating steps”deposition of Eastman-AQ/Ni(II) film and Ni(II)-coating crystalline species onto glassy carbon instead of metallic nickel electrode exhibited stable electrocatalytic oxidation of numerous ∝-hydrogen compounds including carbohydrates, amines and amino acids.Determination of glucose in FIA on the CME, the linear response concentration range was bstween 1.0×10^(-5) and 5.0×10^(-2) mol/L and the detection limit was 5.0×10^(-6)mol/L.The stability of the CME was adequate for routine quantitative application. 展开更多
关键词 AQ EASTMAN-AQ/Ni CHE ii)modified ELECTRODE DETECTION OF CARBOHYDRATES AND AMINO ACIDS CME SCE
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Sound Scattering From Rough Bubbly Ocean Surface Based on Modified Sea Surface Acoustic Simulator and Consideration of Various Incident Angles and Sub-surface Bubbles' Radii 被引量:1
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作者 Alireza Bolghasi Parviz Ghadimi Mohammad A. Feizi Chekab 《Journal of Marine Science and Application》 CSCD 2016年第3期275-287,共13页
The aim of the present study is to improve the capabilities and precision of a recently introduced Sea Surface Acoustic Simulator(SSAS) developed based on optimization of the Helmholtz–Kirchhoff–Fresnel(HKF) method.... The aim of the present study is to improve the capabilities and precision of a recently introduced Sea Surface Acoustic Simulator(SSAS) developed based on optimization of the Helmholtz–Kirchhoff–Fresnel(HKF) method. The improved acoustic simulator, hereby known as the Modified SSAS(MSSAS), is capable of determining sound scattering from the sea surface and includes an extended Hall–Novarini model and optimized HKF method. The extended Hall–Novarini model is used for considering the effects of sub-surface bubbles over a wider range of radii of sub-surface bubbles compared to the previous SSAS version. Furthermore, MSSAS has the capability of making a three-dimensional simulation of scattered sound from the rough bubbly sea surface with less error than that of the Critical Sea Tests(CST) experiments. Also, it presents scattered pressure levels from the rough bubbly sea surface based on various incident angles of sound. Wind speed, frequency, incident angle, and pressure level of the sound source are considered as input data, and scattered pressure levels and scattering coefficients are provided. Finally, different parametric studies were conducted on wind speeds, frequencies, and incident angles to indicate that MSSAS is quite capable of simulating sound scattering from the rough bubbly sea surface, according to the scattering mechanisms determined by Ogden and Erskine. Therefore, it is concluded that MSSAS is valid for both scattering mechanisms and the transition region between them that are defined by Ogden and Erskine. 展开更多
关键词 modified SSAS method scattering strength rough bubbly sea surface wind speed sub-surface bubble plume surface scattering mechanisms
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氨基改性埃洛石对Cu(II)和Cd(II)的吸附研究
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作者 肖雪 于文彬 +3 位作者 谭道永 吴兴福 覃宗华 万泉 《矿物学报》 北大核心 2025年第1期169-180,共12页
本研究采用3-氨丙基三乙氧基硅烷对管状埃洛石(Hal)进行共价接枝制备了氨基改性埃洛石(Hal-NH_(2)),通过XRD、TEM、SEM、氮气吸脱附等手段表征了Hal-NH_(2)的结构特征,并通过批次吸附实验、谱学技术研究了Hal-NH_(2)对Cu(II)和Cd(II)的... 本研究采用3-氨丙基三乙氧基硅烷对管状埃洛石(Hal)进行共价接枝制备了氨基改性埃洛石(Hal-NH_(2)),通过XRD、TEM、SEM、氮气吸脱附等手段表征了Hal-NH_(2)的结构特征,并通过批次吸附实验、谱学技术研究了Hal-NH_(2)对Cu(II)和Cd(II)的吸附性能及机理。Hal-NH_(2)中氨基主要存在于Hal的内腔,其氨基嫁接量为0.83 mmol/L,由于硅烷嫁接占据了部分内腔孔道,Hal-NH_(2)的比表面积和总孔体积较Hal明显降低。Hal-NH_(2)对Cu^(2+)和Cd^(2+)的吸附随溶液初始p H值的增大而增加,吸附时间为2160 min时达到吸附平衡,298 K时,Hal-NH_(2)对Cu^(2+)和Cd^(2+)的Langmuir吸附量分别为50.29和68.70 mg/g,是Hal的3.11和1.97倍。Hal-NH_(2)吸附Cu^(2+)和Cd^(2+)为自发的吸热反应,吸附后体系的混乱度增大,其吸附机制主要是氨基与重金属离子之间发生配位反应,且Hal-NH_(2)对Cu^(2+)的作用力强于Cd^(2+);Cu^(2+)和Cd^(2+)共存时,Hal-NH_(2)对Cu^(2+)的吸附基本不受影响,其对Cd^(2+)的吸附显著降低。由于其较高的吸附能力,Hal-NH_(2)可作为Cu(II)和Cd(II)吸附材料用于水体中重金属离子的去除,本研究为Hal在重金属污染治理领域的应用提供了实验和理论依据。 展开更多
关键词 埃洛石 氨基改性 吸附 重金属 CU(ii) CD(ii)
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The Removal of Cr(III) from Aqueous Solution Using Modified Wool 被引量:1
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作者 Ganchimeg Yunden Naoki Kano Hee-Joon Kim 《Journal of Chemistry and Chemical Engineering》 2019年第2期55-61,共7页
Mongolian sheep wool was modified by maleic anhydride at different temperatures to obtain new adsorbent for the removal of Cr(III). Adsorption of Cr(III) from aqueous solution onto the modified wool was investigated i... Mongolian sheep wool was modified by maleic anhydride at different temperatures to obtain new adsorbent for the removal of Cr(III). Adsorption of Cr(III) from aqueous solution onto the modified wool was investigated in batch system. In this work, the effect of various parameters such as pH, contact time, temperature and initial concentration on the adsorption capacity was determined by ICP-OES (Inductively Coupled Plasma-Optical Emission Spectrometry). Modified wool was characterized by SEM (scanning electron microscopy) and FT-IR (Fourier transform infrared spectrometer). The thermodynamic and kinetic studies were carried out and the results confirmed that the adsorption process was spontaneous in nature, thermodynamically favourable and endothermic. Kinetically, the adsorption process obeys the pseudo-second order model. The modified wool can be an effective adsorbent for the removal of Cr(III) from aqueous solution. 展开更多
关键词 Adsorption CHROMIUM modified WOOL kinetics THERMODYNAMICS
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膝痹宁II通过AMPK/PGC1α信号通路调控糖酵解而减轻膝骨关节炎大鼠软骨损伤
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作者 魏义保 马振源 +5 位作者 刘德仁 胡恩睿 李晓辰 王培民 廖太阳 梅伟 《中国病理生理杂志》 北大核心 2025年第8期1569-1577,共9页
目的:基于AMP活化蛋白激酶(AMPK)/过氧化物酶体增殖物激活受体γ辅激活因子1α(PGC1α)信号通路探讨膝痹宁II(XBN II)调控糖酵解并减轻膝骨关节炎(KOA)大鼠软骨损伤的作用机制。方法:将32只SD大鼠随机分为假手术(sham)组、KOA组、XBN I... 目的:基于AMP活化蛋白激酶(AMPK)/过氧化物酶体增殖物激活受体γ辅激活因子1α(PGC1α)信号通路探讨膝痹宁II(XBN II)调控糖酵解并减轻膝骨关节炎(KOA)大鼠软骨损伤的作用机制。方法:将32只SD大鼠随机分为假手术(sham)组、KOA组、XBN II组和二甲双胍(Met)组,每组8只。通过前交叉韧带切断术建立KOA模型。造模后第14天开始,XBN II组大鼠每日予XBN II灌胃1次,Met组隔天予Met腹腔注射1次,共给药4周。采用HE和番红固绿染色评估软骨组织病理并进行Mankin和OARSI评分;乳酸检测试剂盒检测各组大鼠软骨组织和血清中乳酸含量;免疫组化检测软骨组织中磷酸化AMPK和PGC1α蛋白水平;RT-qPCR和Western blot检测糖酵解相关因子(葡萄糖转运蛋白1、己糖激酶2和乳酸脱氢酶A)、软骨合成和分解代谢相关因子(II型胶原、聚集蛋白聚糖、基质金属蛋白酶13和含血小板应答蛋白基序的解整联蛋白及金属蛋白酶5)及AMPK/PGC1α信号通路相关因子的mRNA和蛋白表达水平。结果:与sham组比较,KOA组大鼠软骨组织和血清中乳酸水平显著升高(P<0.05),软骨组织表面磨损,软骨层结构紊乱,基质淡染,Mankin和OARSI评分显著升高(P<0.05);软骨合成代谢因子及AMPK/PGC1α信号通路相关因子的mRNA和蛋白表达水平显著降低(P<0.05),软骨分解代谢相关因子及糖酵解相关因子的mRNA和蛋白表达水平显著升高(P<0.05)。与KOA组比较,XBN II组和Met组大鼠软骨组织形态有明显改善,Mankin和OARSI评分显著降低,且上述因子的mRNA和蛋白表达水平均显著逆转(P<0.05)。结论:XBN II可通过抑制糖酵解有效减轻KOA大鼠软骨损伤,其作用机制可能与AMPK/PGC1α信号通路的激活有关。 展开更多
关键词 膝痹宁ii 膝骨关节炎 软骨损伤 糖酵解 AMPK/PGC1α信号通路
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TOPAZ-II反应堆控制系统设计验证方案的研究
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作者 张媛媛 贾玉文 张玮瑛 《自动化仪表》 2025年第6期92-96,102,共6页
TOPAZ-II是空间核动力反应堆的代表。针对TOPAZ-II型号自动调节系统的功能要求、架构设计、控制策略及指标要求,研究了反应堆控制系统设计验证方案。自动调节系统设计过程包括需求分析、方案设计、软硬件集成等多个阶段。分析了各阶段... TOPAZ-II是空间核动力反应堆的代表。针对TOPAZ-II型号自动调节系统的功能要求、架构设计、控制策略及指标要求,研究了反应堆控制系统设计验证方案。自动调节系统设计过程包括需求分析、方案设计、软硬件集成等多个阶段。分析了各阶段的验证范围、验证目标、参试设备、指标要求等影响因素。明确了包括高精度仿真、实时数据采集与分析等在内的设计验证平台的功能需求,并确定了主要参试设备的性能指标。通过构建虚拟验证环境,可实现对控制系统性能的早期评估与优化,为后续开展空间核动力反应堆控制系统设计验证提供了技术手段。该研究可有效提高系统设计的可靠性、加速研发进程、降低研发成本。 展开更多
关键词 空间核动力反应堆 TOPAZ-ii 控制系统 全数字仿真 半实物仿真 快速控制原型 设计验证平台
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基于NSGA-II和响应面法的交错内肋微通道热沉的多目标优化 被引量:4
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作者 吕进 彭毅 +1 位作者 关小雅 杨冲 《工程热物理学报》 北大核心 2025年第2期627-637,共11页
微通道热沉因其优越的散热性能,在高性能电子器件散热领域备受青睐。为有效提高交错内肋微通道热沉的散热性能,本文面向交错内肋微通道的多目标优化问题,将非支配排序遗传算法II(NSGA-II)与响应面法相结合,在满足微通道进出口压降最小... 微通道热沉因其优越的散热性能,在高性能电子器件散热领域备受青睐。为有效提高交错内肋微通道热沉的散热性能,本文面向交错内肋微通道的多目标优化问题,将非支配排序遗传算法II(NSGA-II)与响应面法相结合,在满足微通道进出口压降最小和换热面最大温差最小的条件下进行优化。采用Box-Behnken实验设计方法,以肋片迎流角、肋片间距和肋片高度为设计变量,进出口压降和换热面最大温差为目标函数,对热沉的流动和传热性能进行数值模拟研究。为降低进出口压降和提高温度均匀性,采用NSGA-II对微通道热沉的几何参数进行优化,与原设计相比,采用NSGA-II得到的Pareto最优解在进出口压降几乎不变的情况下,换热面最大温差降低了34.922%,在相同泵功下,综合传热性能提高了9.415%。 展开更多
关键词 微通道 数值模拟 多目标优化 NSGA-ii 响应面法
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羧基改性纤维素气凝胶对Ni(II)的去除研究
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作者 陈梁心铭 张丽芳 +1 位作者 宋颖韬 许代兵 《沈阳理工大学学报》 2025年第5期67-73,共7页
为提高纤维素对Ni(II)的吸附效果,通过环氧氯丙烷交联和苹果酸羧基化改性,制备具有良好吸附性能的羧基改性纤维素气凝胶。采用扫描电子显微镜、傅里叶变换红外光谱仪和X射线衍射仪系统表征材料羧基化前后的变化,结果表明,改性过程实现... 为提高纤维素对Ni(II)的吸附效果,通过环氧氯丙烷交联和苹果酸羧基化改性,制备具有良好吸附性能的羧基改性纤维素气凝胶。采用扫描电子显微镜、傅里叶变换红外光谱仪和X射线衍射仪系统表征材料羧基化前后的变化,结果表明,改性过程实现了纤维素表面羟基与苹果酸中羧基的有效酯化,所得气凝胶呈现典型的三维蜂窝状多孔结构。通过条件优化实验发现,当苹果酸与纤维素质量比为1.75∶1、磷酸二氢钠用量为0.5 g/g、130℃反应210 min时,制备的改性纤维素气凝胶在pH为7.0、吸附时间为120 min条件下,对Ni(II)的去除率可达92.61%。动力学及热力学分析结果表明,苹果酸改性纤维素气凝胶对Ni(II)的吸附过程可由准二级动力学模型描述,符合Langmuir等温吸附模型,且为自发进行的吸热过程。 展开更多
关键词 改性纤维素 苹果酸 环氧氯丙烷 吸附 NI(ii)
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