非洲猪瘟(ASF)是猪的一种急性,热性,高度接触性传染病,致死率可达100%。非洲猪瘟病毒(ASFV)是引起该病的病原。ASFV主要感染原代猪单核巨噬细胞系统,仅低效感染少数细胞系,这极大地制约了相应疫苗的研发及对ASFV病原生物学及致病机制的...非洲猪瘟(ASF)是猪的一种急性,热性,高度接触性传染病,致死率可达100%。非洲猪瘟病毒(ASFV)是引起该病的病原。ASFV主要感染原代猪单核巨噬细胞系统,仅低效感染少数细胞系,这极大地制约了相应疫苗的研发及对ASFV病原生物学及致病机制的探索。近期,PLoS Pathogens杂志在线发表了题为“The I7L protein of African swine fever virus is involved in viral pathogenicity by antagonizing the IFN-γ-triggered JAK-STAT signaling pathway through inhibiting the phosphorylation of STAT1”的研究论文,中国农业科学院哈尔滨兽医研究所孙元研究员、李素研究员、仇华吉研究员和李连峰研究员为该论文的共同通讯作者。研究证实,ASFV基因组编码的I7L蛋白可结合STAT1,从而抑制STAT1的磷酸化并拮抗IFN-γ介导的JAK-STAT信号通路,进而调控病毒致病力。该研究为开发ASF弱毒活疫苗提供了新靶点。展开更多
尽管第14代酷睿处理器曾存在不稳定的问题,但由于英特尔后续推出了用于补救的BIOS,且把处理器质保时间延长至5年,并大幅降价,令产品性价比爆棚,就像酷睿i7-14700KF。这款处理器采用经过更新的Raptor Lake S Refresh架构,相对第13代酷睿i...尽管第14代酷睿处理器曾存在不稳定的问题,但由于英特尔后续推出了用于补救的BIOS,且把处理器质保时间延长至5年,并大幅降价,令产品性价比爆棚,就像酷睿i7-14700KF。这款处理器采用经过更新的Raptor Lake S Refresh架构,相对第13代酷睿i7的8P+8E配置,它采用8P+12E的配置,多了4颗能效核核心。展开更多
A bacteria strain for the degradation of hydrolyzed polyacrylamide （HPAM） was isolated from a curing pot in HPAM distribution station of Daqing Oilfield using Hungate anaerobic technique. The isolate was investigate...A bacteria strain for the degradation of hydrolyzed polyacrylamide （HPAM） was isolated from a curing pot in HPAM distribution station of Daqing Oilfield using Hungate anaerobic technique. The isolate was investigated from morphological, physiological, biochemical and molecular characterization. It is a Gram-negative, shortbacillus, non-spore-forming anaerobic bacteria with an optimum growth at 8.0 pH at 40℃. It can reduce sulfate to I-I2S. Alignment of 16S ribosomal DNA and 16S-23S ribosomal DNA intergenic spacer sequences suggests that this isolate is closely related to the Enterobacter cloacae. The isolate is identified as a new strain belonging to Enterobacter genus, temporarily named as Enterobacter cloacae 17. Analysis results of infrared spectroscopy （IR） show that the bacteria can use HPAM as the only carbon source, change the structure of HPAM polymer surface, and realize the hydrolysis of amide to carboxyl group by hydrolysis mechanism. It can degrade the side chain and change some functional groups, which obviously decreases the viscosity. GC-MS analysis indicates that the determined low-molecular weight degradation products of HPAM are polyacrylamide fragments with duplet bond, epoxy as well as carbonyl group, but most of them are acrylamide oligomer derivatives.展开更多
旗舰级的LGA2011平台三年来倒也升级了两代了,今年则会轮到Haswell-E架构登场了,还好这一次的升级力度还是挺大的,CPU要从6核升级到8核,主板要从X79升级到X99,就连主流的DDR3内存也要升级到全新的DDR4了,来了个三位一体的全方位换代。...旗舰级的LGA2011平台三年来倒也升级了两代了,今年则会轮到Haswell-E架构登场了,还好这一次的升级力度还是挺大的,CPU要从6核升级到8核,主板要从X79升级到X99,就连主流的DDR3内存也要升级到全新的DDR4了,来了个三位一体的全方位换代。这两年A M D无心恋战高性能处理器市场,Intel早已高处不胜寒,从Sandy Bridgge到Ivy Bridge再到Haswell,每代处理器升级最大的都是GPU性能。展开更多
GTX950M悍显燃爆勇士心华硕K550 JX采用NV I DI A Ge Force GTX950M悍显,能够展现出更精细的细节和锐利的图像品质,实现了性能上的跨越式提升。外观上,华硕K550JX延续了经典同心圆设计,同时,还配备了一块15.6英寸FHD全高清屏,拥有较普...GTX950M悍显燃爆勇士心华硕K550 JX采用NV I DI A Ge Force GTX950M悍显,能够展现出更精细的细节和锐利的图像品质,实现了性能上的跨越式提升。外观上,华硕K550JX延续了经典同心圆设计,同时,还配备了一块15.6英寸FHD全高清屏,拥有较普通HD屏幕多达2倍的可视范围。Splendid智能靓彩技术的无缝融入,也极大丰富了屏幕的显示色彩,展开更多
一杯热牛奶，一部温情的电影，一个完美的冬日的午后。《当哈里遇上莎莉》讲述了一段跨越时空的爱，一个嵌入在矛盾和挫折中的寻觅，一种“right person right time”的偶然。那么，当英特尔酷睿i7——目前最强大的桌面处理器，遇上玩...一杯热牛奶，一部温情的电影，一个完美的冬日的午后。《当哈里遇上莎莉》讲述了一段跨越时空的爱，一个嵌入在矛盾和挫折中的寻觅，一种“right person right time”的偶然。那么，当英特尔酷睿i7——目前最强大的桌面处理器，遇上玩家国度——业界公认的高端超频首选主板时，是否也会擦出激动人心的火花呢？展开更多
文摘非洲猪瘟(ASF)是猪的一种急性,热性,高度接触性传染病,致死率可达100%。非洲猪瘟病毒(ASFV)是引起该病的病原。ASFV主要感染原代猪单核巨噬细胞系统,仅低效感染少数细胞系,这极大地制约了相应疫苗的研发及对ASFV病原生物学及致病机制的探索。近期,PLoS Pathogens杂志在线发表了题为“The I7L protein of African swine fever virus is involved in viral pathogenicity by antagonizing the IFN-γ-triggered JAK-STAT signaling pathway through inhibiting the phosphorylation of STAT1”的研究论文,中国农业科学院哈尔滨兽医研究所孙元研究员、李素研究员、仇华吉研究员和李连峰研究员为该论文的共同通讯作者。研究证实,ASFV基因组编码的I7L蛋白可结合STAT1,从而抑制STAT1的磷酸化并拮抗IFN-γ介导的JAK-STAT信号通路,进而调控病毒致病力。该研究为开发ASF弱毒活疫苗提供了新靶点。
文摘尽管第14代酷睿处理器曾存在不稳定的问题,但由于英特尔后续推出了用于补救的BIOS,且把处理器质保时间延长至5年,并大幅降价,令产品性价比爆棚,就像酷睿i7-14700KF。这款处理器采用经过更新的Raptor Lake S Refresh架构,相对第13代酷睿i7的8P+8E配置,它采用8P+12E的配置,多了4颗能效核核心。
基金Sponsored by the Country from Branch Fund Significant International Cooperation Item(Grant No.50521140075)
文摘A bacteria strain for the degradation of hydrolyzed polyacrylamide （HPAM） was isolated from a curing pot in HPAM distribution station of Daqing Oilfield using Hungate anaerobic technique. The isolate was investigated from morphological, physiological, biochemical and molecular characterization. It is a Gram-negative, shortbacillus, non-spore-forming anaerobic bacteria with an optimum growth at 8.0 pH at 40℃. It can reduce sulfate to I-I2S. Alignment of 16S ribosomal DNA and 16S-23S ribosomal DNA intergenic spacer sequences suggests that this isolate is closely related to the Enterobacter cloacae. The isolate is identified as a new strain belonging to Enterobacter genus, temporarily named as Enterobacter cloacae 17. Analysis results of infrared spectroscopy （IR） show that the bacteria can use HPAM as the only carbon source, change the structure of HPAM polymer surface, and realize the hydrolysis of amide to carboxyl group by hydrolysis mechanism. It can degrade the side chain and change some functional groups, which obviously decreases the viscosity. GC-MS analysis indicates that the determined low-molecular weight degradation products of HPAM are polyacrylamide fragments with duplet bond, epoxy as well as carbonyl group, but most of them are acrylamide oligomer derivatives.
文摘旗舰级的LGA2011平台三年来倒也升级了两代了,今年则会轮到Haswell-E架构登场了,还好这一次的升级力度还是挺大的,CPU要从6核升级到8核,主板要从X79升级到X99,就连主流的DDR3内存也要升级到全新的DDR4了,来了个三位一体的全方位换代。这两年A M D无心恋战高性能处理器市场,Intel早已高处不胜寒,从Sandy Bridgge到Ivy Bridge再到Haswell,每代处理器升级最大的都是GPU性能。
文摘GTX950M悍显燃爆勇士心华硕K550 JX采用NV I DI A Ge Force GTX950M悍显,能够展现出更精细的细节和锐利的图像品质,实现了性能上的跨越式提升。外观上,华硕K550JX延续了经典同心圆设计,同时,还配备了一块15.6英寸FHD全高清屏,拥有较普通HD屏幕多达2倍的可视范围。Splendid智能靓彩技术的无缝融入,也极大丰富了屏幕的显示色彩,
文摘一杯热牛奶，一部温情的电影，一个完美的冬日的午后。《当哈里遇上莎莉》讲述了一段跨越时空的爱，一个嵌入在矛盾和挫折中的寻觅，一种“right person right time”的偶然。那么，当英特尔酷睿i7——目前最强大的桌面处理器，遇上玩家国度——业界公认的高端超频首选主板时，是否也会擦出激动人心的火花呢？
