The intersection between obesity-related metabolic inflammation and hypothalamic–pituitary–gonadal(HPG)axis dysfunction in adolescents has emerged as one of the most significant paradigm shifts in contemporary repro...The intersection between obesity-related metabolic inflammation and hypothalamic–pituitary–gonadal(HPG)axis dysfunction in adolescents has emerged as one of the most significant paradigm shifts in contemporary reproductive endocrinology[1].Mounting evidence indicates that chronic low-grade inflammation induces both functional and structural changes in the hypothalamus.展开更多
文摘The intersection between obesity-related metabolic inflammation and hypothalamic–pituitary–gonadal(HPG)axis dysfunction in adolescents has emerged as one of the most significant paradigm shifts in contemporary reproductive endocrinology[1].Mounting evidence indicates that chronic low-grade inflammation induces both functional and structural changes in the hypothalamus.
