BACKGROUND Varicocele embolization,a minimally invasive treatment for symptomatic varicoceles,carries a rare risk of complications like ureteral obstruction and hydronephrosis.This case report documents such a case to...BACKGROUND Varicocele embolization,a minimally invasive treatment for symptomatic varicoceles,carries a rare risk of complications like ureteral obstruction and hydronephrosis.This case report documents such a case to raise awareness of these potential complications and showcase minimally invasive surgical management as a successful solution.CASE SUMMARY A 35-year-old male presented with flank pain and hematuria following varicocele embolization.Imaging confirmed left ureteral obstruction and hydronephrosis.Laparoscopic ureterolysis successfully removed the embolization coil and repaired the ureter,resolving the patient's symptoms.Follow-up at six months and two years showed sustained improvement.CONCLUSION Minimally invasive surgery offers an effective treatment option for rare complications like ureteral obstruction arising from varicocele embolization.展开更多
Hydronephrosis and ureteral obstruction are rare sequelae of Crohn’s disease. Chronic obstruction can ultimately lead to dysfunction of the affected kidney, and atypical presenting symptoms create pitfalls in diagnos...Hydronephrosis and ureteral obstruction are rare sequelae of Crohn’s disease. Chronic obstruction can ultimately lead to dysfunction of the affected kidney, and atypical presenting symptoms create pitfalls in diagnosis. Few reviews in the literature focus on this process and are limited to isolated case reports and case reviews. We performed a PubMed search using such terms as “Hydronephrosis” AND “Crohn’s disease” AND/OR “ureteral obstruction.” References from selected papers were reviewed for relevance and used for information-gathering as well. Ureteral obstruction most commonly occurs on the right side, due to ileal involvement. Clinical diagnosis is difficult, as symptoms are notably not genitourinary in origin;rather they are more musculoskeletal in nature. Treatment centers on disease control and temporary drainage of the affected kidney. Though rare, hydronephrosis and ureteral obstruction may develop as a result of inflammatory bowel disease. Due to atypical presenting symptoms, a high clinical suspicion is needed to affirm the diagnosis and ensure proper treatment.展开更多
Giant Hydronephrosis (GH) is a rare condition in urology literature and defined as a pelvicalyceal system of kidney containing more of 1000 ml of urine. This condition is not so rare in our setting. We herein, reporte...Giant Hydronephrosis (GH) is a rare condition in urology literature and defined as a pelvicalyceal system of kidney containing more of 1000 ml of urine. This condition is not so rare in our setting. We herein, reported two cases of giant hydronephrosis, seen in two young patients respectively with 5 and 9 years old and their collecting system containing 4000 ml and 5000 ml of urines respectively. Only simple nephrectomy was performed for the two cases with renal function impairment and the post operative course was uneventful. Our purpose through these cases reports is to discuss diagnosis features and management of such condition in our setting, a context of low income countries as Burkina-Faso where diagnosis tool and further investigation are not always available.展开更多
In their retrospective study of 298 diabetic patients with renal/ureteral calculi,Zhou et al identified critical predictors for urosepsis using multivariate logisticregression.Key findings revealed female gender(OR=2....In their retrospective study of 298 diabetic patients with renal/ureteral calculi,Zhou et al identified critical predictors for urosepsis using multivariate logisticregression.Key findings revealed female gender(OR=2.237,P=0.03),advancedage(OR=1.05/year,P=0.002),fever(OR=2.999,P=0.015),severe hydronephrosis(OR=6.129,P=0.011),and elevated urinary markers-particularly urineleukocytes(U-LEU+++:OR=66.0,P<0.001)and glucose(U-GLU+++:OR=7.248,P=0.005)as independent risk factors.These readily accessible clinicalparameters offer significant potential for early risk stratification in high-riskpopulations.While this STROBE-adherent study provides actionable insights,limitations include its single-center design and unaddressed antibiotic protocols.Future multicenter validation should assess residual stone impacts and optimizeintervention thresholds.This work establishes a foundation for targeted surveillanceprotocols in diabetic urolithiasis management.展开更多
Dear Colleagues,It is my distinct honor to serve as the Honorary Chief Editor of AMEM,an international open-access journal,dedicated to serve as a platform for international exchange,and the translation of research ou...Dear Colleagues,It is my distinct honor to serve as the Honorary Chief Editor of AMEM,an international open-access journal,dedicated to serve as a platform for international exchange,and the translation of research outcomes in the field of life sciences.AMEM strives to establish itself as a high-level international academic exchange platform that brings together scientific wisdom from around the world and offers a prestigious journal for presenting research findings,and disseminating state of the art knowledge in the vibrant fields of life sciences.展开更多
BACKGROUND Urosepsis is a life-threatening condition frequently associated with renal and ureteral calculi(RUC)and diabetes mellitus(DM),a combination that exacerbates susceptibility to infection due to urinary obstru...BACKGROUND Urosepsis is a life-threatening condition frequently associated with renal and ureteral calculi(RUC)and diabetes mellitus(DM),a combination that exacerbates susceptibility to infection due to urinary obstruction and impaired immune response.AIM To identify the risk factors for urosepsis in patients with RUC complicated by DM to enhance early detection and intervention strategies.METHODS This retrospective observational study included 298 patients with RUC and DM admitted between January 2020 and June 2024.Patients were divided into an observation group(n=32)with urosepsis and a control group(n=266)without urosepsis.Comprehensive clinical,laboratory,and imaging data were collected and analyzed using univariate and multivariate logistic regression models to identify factors associated with urosepsis.The study adhered to the STROBE guidelines and received ethical approval.RESULTS Multivariate analysis identified several independent risk factors for urosepsis.Female sex(OR=2.237,95%CI:1.086-4.605,P=0.03),advanced age(OR=1.05,95%CI:1.018-1.084,P=0.002),and fever(OR=2.999,95%CI:1.283-7.015,P=0.015)significantly increased the risk.Laboratory findings such as elevated urine leukocyte(U-LEU)(+++,OR=66.0,95%CI:7.031–580.125,P<0.001)and glucose(U-GLU)(+++,OR=7.248,95%CI:1.862-28.211,P=0.005)levels were strongly associated with urosepsis.Severe hydronephrosis also emerged as a significant predictor(OR=6.129,95%CI:3.027-9.623,P=0.011).Other factors,such as gross hematuria,stone laterality,and mild to moderate hydronephrosis,were not significantly associated with urosepsis.CONCLUSION This study identifies key demographic,clinical,laboratory,and imaging factors associated with urosepsis risk in patients with RUC and DM.Early identification of female patients,elderly individuals,those presenting with fever,severe hydronephrosis,and elevated U-LEU and U-GLU levels may facilitate timely intervention.These findings highlight the importance of comprehensive assessment and targeted management in the care of high-risk patients.展开更多
文摘BACKGROUND Varicocele embolization,a minimally invasive treatment for symptomatic varicoceles,carries a rare risk of complications like ureteral obstruction and hydronephrosis.This case report documents such a case to raise awareness of these potential complications and showcase minimally invasive surgical management as a successful solution.CASE SUMMARY A 35-year-old male presented with flank pain and hematuria following varicocele embolization.Imaging confirmed left ureteral obstruction and hydronephrosis.Laparoscopic ureterolysis successfully removed the embolization coil and repaired the ureter,resolving the patient's symptoms.Follow-up at six months and two years showed sustained improvement.CONCLUSION Minimally invasive surgery offers an effective treatment option for rare complications like ureteral obstruction arising from varicocele embolization.
文摘Hydronephrosis and ureteral obstruction are rare sequelae of Crohn’s disease. Chronic obstruction can ultimately lead to dysfunction of the affected kidney, and atypical presenting symptoms create pitfalls in diagnosis. Few reviews in the literature focus on this process and are limited to isolated case reports and case reviews. We performed a PubMed search using such terms as “Hydronephrosis” AND “Crohn’s disease” AND/OR “ureteral obstruction.” References from selected papers were reviewed for relevance and used for information-gathering as well. Ureteral obstruction most commonly occurs on the right side, due to ileal involvement. Clinical diagnosis is difficult, as symptoms are notably not genitourinary in origin;rather they are more musculoskeletal in nature. Treatment centers on disease control and temporary drainage of the affected kidney. Though rare, hydronephrosis and ureteral obstruction may develop as a result of inflammatory bowel disease. Due to atypical presenting symptoms, a high clinical suspicion is needed to affirm the diagnosis and ensure proper treatment.
文摘Giant Hydronephrosis (GH) is a rare condition in urology literature and defined as a pelvicalyceal system of kidney containing more of 1000 ml of urine. This condition is not so rare in our setting. We herein, reported two cases of giant hydronephrosis, seen in two young patients respectively with 5 and 9 years old and their collecting system containing 4000 ml and 5000 ml of urines respectively. Only simple nephrectomy was performed for the two cases with renal function impairment and the post operative course was uneventful. Our purpose through these cases reports is to discuss diagnosis features and management of such condition in our setting, a context of low income countries as Burkina-Faso where diagnosis tool and further investigation are not always available.
基金Supported by National Natural Science Foundation of China,No.82300780Natural Science Foundation of Jiangsu Province,No.BK20220306Yancheng Key Research and Development Plan(Social Development)Project,No.YCBE202214.
文摘In their retrospective study of 298 diabetic patients with renal/ureteral calculi,Zhou et al identified critical predictors for urosepsis using multivariate logisticregression.Key findings revealed female gender(OR=2.237,P=0.03),advancedage(OR=1.05/year,P=0.002),fever(OR=2.999,P=0.015),severe hydronephrosis(OR=6.129,P=0.011),and elevated urinary markers-particularly urineleukocytes(U-LEU+++:OR=66.0,P<0.001)and glucose(U-GLU+++:OR=7.248,P=0.005)as independent risk factors.These readily accessible clinicalparameters offer significant potential for early risk stratification in high-riskpopulations.While this STROBE-adherent study provides actionable insights,limitations include its single-center design and unaddressed antibiotic protocols.Future multicenter validation should assess residual stone impacts and optimizeintervention thresholds.This work establishes a foundation for targeted surveillanceprotocols in diabetic urolithiasis management.
文摘Dear Colleagues,It is my distinct honor to serve as the Honorary Chief Editor of AMEM,an international open-access journal,dedicated to serve as a platform for international exchange,and the translation of research outcomes in the field of life sciences.AMEM strives to establish itself as a high-level international academic exchange platform that brings together scientific wisdom from around the world and offers a prestigious journal for presenting research findings,and disseminating state of the art knowledge in the vibrant fields of life sciences.
文摘BACKGROUND Urosepsis is a life-threatening condition frequently associated with renal and ureteral calculi(RUC)and diabetes mellitus(DM),a combination that exacerbates susceptibility to infection due to urinary obstruction and impaired immune response.AIM To identify the risk factors for urosepsis in patients with RUC complicated by DM to enhance early detection and intervention strategies.METHODS This retrospective observational study included 298 patients with RUC and DM admitted between January 2020 and June 2024.Patients were divided into an observation group(n=32)with urosepsis and a control group(n=266)without urosepsis.Comprehensive clinical,laboratory,and imaging data were collected and analyzed using univariate and multivariate logistic regression models to identify factors associated with urosepsis.The study adhered to the STROBE guidelines and received ethical approval.RESULTS Multivariate analysis identified several independent risk factors for urosepsis.Female sex(OR=2.237,95%CI:1.086-4.605,P=0.03),advanced age(OR=1.05,95%CI:1.018-1.084,P=0.002),and fever(OR=2.999,95%CI:1.283-7.015,P=0.015)significantly increased the risk.Laboratory findings such as elevated urine leukocyte(U-LEU)(+++,OR=66.0,95%CI:7.031–580.125,P<0.001)and glucose(U-GLU)(+++,OR=7.248,95%CI:1.862-28.211,P=0.005)levels were strongly associated with urosepsis.Severe hydronephrosis also emerged as a significant predictor(OR=6.129,95%CI:3.027-9.623,P=0.011).Other factors,such as gross hematuria,stone laterality,and mild to moderate hydronephrosis,were not significantly associated with urosepsis.CONCLUSION This study identifies key demographic,clinical,laboratory,and imaging factors associated with urosepsis risk in patients with RUC and DM.Early identification of female patients,elderly individuals,those presenting with fever,severe hydronephrosis,and elevated U-LEU and U-GLU levels may facilitate timely intervention.These findings highlight the importance of comprehensive assessment and targeted management in the care of high-risk patients.
