Introduction: Dental caries is the most prevalent chronic disease among schoolchildren. We aimed to investigate the association between dental caries index and socio-demographic status in schoolchildren by using a mul...Introduction: Dental caries is the most prevalent chronic disease among schoolchildren. We aimed to investigate the association between dental caries index and socio-demographic status in schoolchildren by using a multilevel hurdle model. Materials and Methods: A cross-sectional epidemiological study was carried out on 906 primary school pupils in Kerman, Iran in 2012. The subjects were selected through a stratified cluster random sampling. At first, the whole target area was stratified according to two geographic areas, the north and south area. Then each area was stratified according to gender. In the next step, several schools were considered as clusters, which were selected randomly in each geographic area and gender strata. All the schoolchildren in these schools were included in this study as samples. Twelve-year-old pupils were examined for dental caries. The dependent variable in this study was the dmft/DMFT index. Eight variables, including socio-demographic information, were collected. Multilevel negative binomial hurdle model was employed for data analysis. Results: The prevalence of caries-free pupils was 30.1% and the mean dmft/DMFT was 3.6 ± 2.2. Negative binomial part of the adjusted model showed that the dmft/DMFT adjusted rate for females was 1.36 (95% CI: 1.10-1.79) times higher than males. Also, the dmft/DMFT adjusted rate for overweight pupils was 0.86 (95% CI: 0.74-0.98) times lower than those with normal weight. Logistic part of the adjusted model showed that the posibility of caries-free state in overweight pupils was 1.95 (95% CI: 1.22-3.11) times higher than those with normal weight. In addition, pupils whose fathers and mothers were workers and housewives, respectively, and those with a high maternal age were at a greater risk for caries experience than others (p < 0.05). Conclusion: BMI, gender, parent’s job and mother’s age at delivery were factors effecting on dental caries in schoolchildren. These pupils need more attention to dental care.展开更多
The rise of non-marital fertility, which seems to defy the Bongaarts model by decoupling marriage from fertility, has become a subject of interest in both the developed and developing world. Consequences of non-marita...The rise of non-marital fertility, which seems to defy the Bongaarts model by decoupling marriage from fertility, has become a subject of interest in both the developed and developing world. Consequences of non-marital fertility are mostly negative particularly in developing countries. In Namibia, although premarital childbearing has been reported to be high and increasing, no studies have explicitly analyzed factors influencing non-marital fertility. This paper uses data from the 2006/7 Namibia DHS to establish the determinants of non-marital fertility among women by applying a two-part model, with one part to describe the presence of non-marital birth and the other part to explain its intensity （number of children born）. Using the number of children ever born as an outcome, we explored various count data models. Based on the Voung statistics model comparison, we settled for the Hurdle logit Negative Binomial regression to model the number of non-marital births. Non-marital fertility in Namibia is associated with the age, with young women likely to have lower fertility compared to older women. Women with secondary or higher education had lower fertility compared those with no formal education. Findings also show that rural women higher fertility propensity compared to their urban counterparts even though there was no significant difference in fertility intensity. With regard to socio-economic status, fertility intensity decreased as the women got richer. Intervention efforts should focus on promoting education among girls and women especially in rural areas to improve their socio-economic status, reduce teenage pregnancy and non-marital fertility.展开更多
Russia on November 10 cleared the last major obstacle in its 18-year effort to join the World Trade Organization in what the head of the institution called a milestone for global trade. "It’s a victory for Russi...Russia on November 10 cleared the last major obstacle in its 18-year effort to join the World Trade Organization in what the head of the institution called a milestone for global trade. "It’s a victory for Russia, a victory for W.T.O. members, and a victory展开更多
Purpose:To explore the parental factors that impede early intervention for strabismus and thus identify strategies for improving access to specialized care.Methods:This hospital-based cross-sectional study included 11...Purpose:To explore the parental factors that impede early intervention for strabismus and thus identify strategies for improving access to specialized care.Methods:This hospital-based cross-sectional study included 110 parents of children under 19 years with strabismus receiving treatment at the squint clinic of a tertiary health care center in north India.A pre-validated survey questionnaire was administered to the participants,that had a section about the socio-demographics of the participants,another section addressed the parental knowledge about strabismus about diagnosis,and the need for an eye examination.It also sought information about referral source,the felt need for squint examination,and reasons for not seeking treatment.Results:A total of 110 parents/guardians of strabismus patients(59 exotropes and 51 esotropes)were interviewed using a survey questionnaire.Parents themselves identified 80%of cases,and a substantial link(P<0.0001)was found between the education status of parents and the age of identification of strabismus.Fear of surgical outcomes(41.79%)was a significant barrier to timely surgery with a higher percentage of parents expressing fear of surgical outcomes(P=0.025).The cost of surgery(34.33%)and the non-availability of facilities(23.88%)also delayed the intervention.Conclusions:It is essential to educate parents about the importance of strabismus therapy at an appropriate time,stressing its reconstructive rather than merely cosmetic nature,as there are notable gaps in their knowledge.Also,we need to do away with the fear of surgical outcomes of surgical interventions for strabismus.展开更多
Fresh fish is a highly perishable product due to the chemical composition of fish flesh and the high microbial load on fish surface.The natural microflora that is more adopted to low temperatures results also in lower...Fresh fish is a highly perishable product due to the chemical composition of fish flesh and the high microbial load on fish surface.The natural microflora that is more adopted to low temperatures results also in lower thermal bacterial shock from natural temperature to the preservation temperature range.The development of new fish processing(e.g.high hydrostatic pressure,osmotic dehydration,high-intensity pulsed light)and packaging(e.g.modified atmospheres,active and intelligent packaging)methods or novel combinations of existing technologies is sought by the industry in the pursuit of producing alternative products,achieving shelf life extension,and management and reducing food waste.In 2014,processed fish was among the most active new product categories.The lack of dissemination of validated laboratory results for the seafood industry is one of the major issues preventing the uptake of minimal and nonthermal processing for fresh fish.However,it has been reported that some bacteria become more resistant under stress(e.g.psychrotolerant lactobacilli).At the same time,the application of some processing methods(e.g.thermal processing)may affect significantly the nutritional and sensory profile of the target food product.The application of several“soft hurdles”may reduce the rate of fish deterioration and spoilage caused by microbial growth.The objective of this article is to review the preservative effect of alternative hurdles on fish quality and shelf life,focusing on recent,combined applications.展开更多
Fresh fish,and especially fatty species,are highly perishable due to oxidative deterioration of fish flesh and the elevated microbial load on fish surface.The implementation of a variety of“mild hurdles”may signific...Fresh fish,and especially fatty species,are highly perishable due to oxidative deterioration of fish flesh and the elevated microbial load on fish surface.The implementation of a variety of“mild hurdles”may significantly decrease the rates of fish chemical degradation and microbiological spoilage,by better retaining the initial quality,compared to more intense preservation techniques.The aim of this work is the comparative study of different,single or combined,treatments at 15℃on the quality and shelf life of chilled eel fillets.Fish fillets were treated using osmotic solutions consisting of glycerol(30%–40%–45%)and 5%NaCl with and without former antioxidant impregnation by using Rosemary Serum.In all cases,water activity decreased to approximately 0.90 after 420 min of osmotic treatment.Untreated and osmotically treated fish fillets were subsequently stored at 4℃and their stability under chill conditions was assessed based on microbial growth and oxidative deterioration.Microbial growth of treated samples was significantly delayed,especially due to the osmotic step(OS)and the derived water activity decrease.Lipid oxidation,a major cause of rejection for fatty fish such as eel,was greatly inhibited in treated fillets,owing to both‘hurdles’,aw lowering(OS)and antioxidant impregnation with rosemary serum(RS/OS),showing the synergistic effect of these successive procedures.Shelf life of treated eel fillets exhibited a more than 10-fold increase,as compared to the untreated samples,based on chemical composition and a 2 to 3-fold shelf life improvement,in terms of microbial growth.展开更多
Background:Wildfires play a key role in shaping Mediterranean landscapes and ecosystems and in impacting species dynamics.Numerous studies have investigated the wildfire occurrences and the influence of their drivers ...Background:Wildfires play a key role in shaping Mediterranean landscapes and ecosystems and in impacting species dynamics.Numerous studies have investigated the wildfire occurrences and the influence of their drivers in many countries of the Mediterranean Basin.However,in this regard,no studies have attempted to compare different Mediterranean regions,which may appear similar under many aspects.In response to this gap,climatic,topographic,anthropic,and landscape drivers were analyzed and compared to assess the patterns of fire ignition points in terms of fire occurrence and frequency in Catalonia(Spain),Sardinia,and Apulia(Italy).Therefore,the objectives of the study were to(1)assess fire ignition occurrence in terms of probability and frequency,(2)compare the main drivers affecting fire occurrence,and(3)produce fire probability and frequency maps for each region.Results:In pursuit of the above,the probability of fire ignition occurrence and frequency was mapped using Negative Binomial Hurdle models,while the models’performances were evaluated using several metrics(AUC,prediction accuracy,RMSE,and the Pearson correlation coefficient).The results showed an inverse correlation between distance from infrastructures(i.e.,urban roads and areas)and the occurrence of fires in all three study regions.This relationship became more significant when the frequency of fire ignition points was assessed.Moreover,a positive correlation was found between fire occurrence and landscape drivers according to region.The land cover classes more significantly affected were forest,agriculture,and grassland for Catalonia,Sardinia,and Apulia,respectively.Conclusions:Compared to the climatic,topographic,and landscape drivers,anthropic activity significantly influences fire ignition and frequency in all three regions.When the distance from urban roads and areas decreases,the probability of fire ignition occurrence and frequency increases.Consequently,it is essential to implement long-to medium-term intervention plans to reduce the proximity between potential ignition points and fuels.In this perspective,the present study provides an applicable decision-making tool to improve wildfire prevention strategies at the European level in an area like the Mediterranean Basin where a profuse number of wildfires take place.展开更多
Slightly acidic electrolyzed water(SAEW)has proven to be an efficient and novel sanitizer in food and agriculture field.This study assessed the efficacy of SAEW(30 mg/L)at 40℃on the inactivation of foodbome pathogens...Slightly acidic electrolyzed water(SAEW)has proven to be an efficient and novel sanitizer in food and agriculture field.This study assessed the efficacy of SAEW(30 mg/L)at 40℃on the inactivation of foodbome pathogens and detachment of multi-resistant Staphylococcus aureus(MRSA)biofilm.Furthermore.the underlying mechanism of MRS A biofilm under heated SAEW at 40℃treatment on metabolic profiles was investigated.The results showed that the heated SAEW at 40℃significantly effectively against foodbome pathogens of 1.96-7.56(lg(CFU/g))reduction in pork,chicken,spinach,and lettuce.The heated SAEW at 40℃treatment significantly reduced MRS A biofilm cells by 2.41(lg(CFU/cm^(2))).The synergistic effect of SAEW treatment showed intense anti-biofilm activity in decreasing cell density and impairing biofilm cell membranes.Global metabolic response of MRSA biofilms,treated by SAEW at 40℃,revealed the alterations of intracellular metabolites,including amino acids,organic acid,fatty acid,and lipid.Moreover,signaling pathways involved in amino acid metabolism,energy metabolism,nucleotide synthesis,carbohydrate metabolites,and lipid biosynthesis were functionally disrupted by the SAEW at 40℃treatment.As per our knowledge,this is the first research to uncover the potential mechanism of heated SAEW treatment against MRSA biofilm on food contact surface.展开更多
文摘Introduction: Dental caries is the most prevalent chronic disease among schoolchildren. We aimed to investigate the association between dental caries index and socio-demographic status in schoolchildren by using a multilevel hurdle model. Materials and Methods: A cross-sectional epidemiological study was carried out on 906 primary school pupils in Kerman, Iran in 2012. The subjects were selected through a stratified cluster random sampling. At first, the whole target area was stratified according to two geographic areas, the north and south area. Then each area was stratified according to gender. In the next step, several schools were considered as clusters, which were selected randomly in each geographic area and gender strata. All the schoolchildren in these schools were included in this study as samples. Twelve-year-old pupils were examined for dental caries. The dependent variable in this study was the dmft/DMFT index. Eight variables, including socio-demographic information, were collected. Multilevel negative binomial hurdle model was employed for data analysis. Results: The prevalence of caries-free pupils was 30.1% and the mean dmft/DMFT was 3.6 ± 2.2. Negative binomial part of the adjusted model showed that the dmft/DMFT adjusted rate for females was 1.36 (95% CI: 1.10-1.79) times higher than males. Also, the dmft/DMFT adjusted rate for overweight pupils was 0.86 (95% CI: 0.74-0.98) times lower than those with normal weight. Logistic part of the adjusted model showed that the posibility of caries-free state in overweight pupils was 1.95 (95% CI: 1.22-3.11) times higher than those with normal weight. In addition, pupils whose fathers and mothers were workers and housewives, respectively, and those with a high maternal age were at a greater risk for caries experience than others (p < 0.05). Conclusion: BMI, gender, parent’s job and mother’s age at delivery were factors effecting on dental caries in schoolchildren. These pupils need more attention to dental care.
文摘The rise of non-marital fertility, which seems to defy the Bongaarts model by decoupling marriage from fertility, has become a subject of interest in both the developed and developing world. Consequences of non-marital fertility are mostly negative particularly in developing countries. In Namibia, although premarital childbearing has been reported to be high and increasing, no studies have explicitly analyzed factors influencing non-marital fertility. This paper uses data from the 2006/7 Namibia DHS to establish the determinants of non-marital fertility among women by applying a two-part model, with one part to describe the presence of non-marital birth and the other part to explain its intensity （number of children born）. Using the number of children ever born as an outcome, we explored various count data models. Based on the Voung statistics model comparison, we settled for the Hurdle logit Negative Binomial regression to model the number of non-marital births. Non-marital fertility in Namibia is associated with the age, with young women likely to have lower fertility compared to older women. Women with secondary or higher education had lower fertility compared those with no formal education. Findings also show that rural women higher fertility propensity compared to their urban counterparts even though there was no significant difference in fertility intensity. With regard to socio-economic status, fertility intensity decreased as the women got richer. Intervention efforts should focus on promoting education among girls and women especially in rural areas to improve their socio-economic status, reduce teenage pregnancy and non-marital fertility.
文摘Russia on November 10 cleared the last major obstacle in its 18-year effort to join the World Trade Organization in what the head of the institution called a milestone for global trade. "It’s a victory for Russia, a victory for W.T.O. members, and a victory
文摘Purpose:To explore the parental factors that impede early intervention for strabismus and thus identify strategies for improving access to specialized care.Methods:This hospital-based cross-sectional study included 110 parents of children under 19 years with strabismus receiving treatment at the squint clinic of a tertiary health care center in north India.A pre-validated survey questionnaire was administered to the participants,that had a section about the socio-demographics of the participants,another section addressed the parental knowledge about strabismus about diagnosis,and the need for an eye examination.It also sought information about referral source,the felt need for squint examination,and reasons for not seeking treatment.Results:A total of 110 parents/guardians of strabismus patients(59 exotropes and 51 esotropes)were interviewed using a survey questionnaire.Parents themselves identified 80%of cases,and a substantial link(P<0.0001)was found between the education status of parents and the age of identification of strabismus.Fear of surgical outcomes(41.79%)was a significant barrier to timely surgery with a higher percentage of parents expressing fear of surgical outcomes(P=0.025).The cost of surgery(34.33%)and the non-availability of facilities(23.88%)also delayed the intervention.Conclusions:It is essential to educate parents about the importance of strabismus therapy at an appropriate time,stressing its reconstructive rather than merely cosmetic nature,as there are notable gaps in their knowledge.Also,we need to do away with the fear of surgical outcomes of surgical interventions for strabismus.
基金the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant agreement 872217.
文摘Fresh fish is a highly perishable product due to the chemical composition of fish flesh and the high microbial load on fish surface.The natural microflora that is more adopted to low temperatures results also in lower thermal bacterial shock from natural temperature to the preservation temperature range.The development of new fish processing(e.g.high hydrostatic pressure,osmotic dehydration,high-intensity pulsed light)and packaging(e.g.modified atmospheres,active and intelligent packaging)methods or novel combinations of existing technologies is sought by the industry in the pursuit of producing alternative products,achieving shelf life extension,and management and reducing food waste.In 2014,processed fish was among the most active new product categories.The lack of dissemination of validated laboratory results for the seafood industry is one of the major issues preventing the uptake of minimal and nonthermal processing for fresh fish.However,it has been reported that some bacteria become more resistant under stress(e.g.psychrotolerant lactobacilli).At the same time,the application of some processing methods(e.g.thermal processing)may affect significantly the nutritional and sensory profile of the target food product.The application of several“soft hurdles”may reduce the rate of fish deterioration and spoilage caused by microbial growth.The objective of this article is to review the preservative effect of alternative hurdles on fish quality and shelf life,focusing on recent,combined applications.
文摘Fresh fish,and especially fatty species,are highly perishable due to oxidative deterioration of fish flesh and the elevated microbial load on fish surface.The implementation of a variety of“mild hurdles”may significantly decrease the rates of fish chemical degradation and microbiological spoilage,by better retaining the initial quality,compared to more intense preservation techniques.The aim of this work is the comparative study of different,single or combined,treatments at 15℃on the quality and shelf life of chilled eel fillets.Fish fillets were treated using osmotic solutions consisting of glycerol(30%–40%–45%)and 5%NaCl with and without former antioxidant impregnation by using Rosemary Serum.In all cases,water activity decreased to approximately 0.90 after 420 min of osmotic treatment.Untreated and osmotically treated fish fillets were subsequently stored at 4℃and their stability under chill conditions was assessed based on microbial growth and oxidative deterioration.Microbial growth of treated samples was significantly delayed,especially due to the osmotic step(OS)and the derived water activity decrease.Lipid oxidation,a major cause of rejection for fatty fish such as eel,was greatly inhibited in treated fillets,owing to both‘hurdles’,aw lowering(OS)and antioxidant impregnation with rosemary serum(RS/OS),showing the synergistic effect of these successive procedures.Shelf life of treated eel fillets exhibited a more than 10-fold increase,as compared to the untreated samples,based on chemical composition and a 2 to 3-fold shelf life improvement,in terms of microbial growth.
文摘Background:Wildfires play a key role in shaping Mediterranean landscapes and ecosystems and in impacting species dynamics.Numerous studies have investigated the wildfire occurrences and the influence of their drivers in many countries of the Mediterranean Basin.However,in this regard,no studies have attempted to compare different Mediterranean regions,which may appear similar under many aspects.In response to this gap,climatic,topographic,anthropic,and landscape drivers were analyzed and compared to assess the patterns of fire ignition points in terms of fire occurrence and frequency in Catalonia(Spain),Sardinia,and Apulia(Italy).Therefore,the objectives of the study were to(1)assess fire ignition occurrence in terms of probability and frequency,(2)compare the main drivers affecting fire occurrence,and(3)produce fire probability and frequency maps for each region.Results:In pursuit of the above,the probability of fire ignition occurrence and frequency was mapped using Negative Binomial Hurdle models,while the models’performances were evaluated using several metrics(AUC,prediction accuracy,RMSE,and the Pearson correlation coefficient).The results showed an inverse correlation between distance from infrastructures(i.e.,urban roads and areas)and the occurrence of fires in all three study regions.This relationship became more significant when the frequency of fire ignition points was assessed.Moreover,a positive correlation was found between fire occurrence and landscape drivers according to region.The land cover classes more significantly affected were forest,agriculture,and grassland for Catalonia,Sardinia,and Apulia,respectively.Conclusions:Compared to the climatic,topographic,and landscape drivers,anthropic activity significantly influences fire ignition and frequency in all three regions.When the distance from urban roads and areas decreases,the probability of fire ignition occurrence and frequency increases.Consequently,it is essential to implement long-to medium-term intervention plans to reduce the proximity between potential ignition points and fuels.In this perspective,the present study provides an applicable decision-making tool to improve wildfire prevention strategies at the European level in an area like the Mediterranean Basin where a profuse number of wildfires take place.
基金supported by Brain Korea (BK)21 Plus Project (4299990913942)funded by the Korean Government,Koreathe Collabo Project funded by the Ministry of SMEs and Startups (C1016120-01-02)the National Research Foundation of Korea (NRF) (2018007551)。
文摘Slightly acidic electrolyzed water(SAEW)has proven to be an efficient and novel sanitizer in food and agriculture field.This study assessed the efficacy of SAEW(30 mg/L)at 40℃on the inactivation of foodbome pathogens and detachment of multi-resistant Staphylococcus aureus(MRSA)biofilm.Furthermore.the underlying mechanism of MRS A biofilm under heated SAEW at 40℃treatment on metabolic profiles was investigated.The results showed that the heated SAEW at 40℃significantly effectively against foodbome pathogens of 1.96-7.56(lg(CFU/g))reduction in pork,chicken,spinach,and lettuce.The heated SAEW at 40℃treatment significantly reduced MRS A biofilm cells by 2.41(lg(CFU/cm^(2))).The synergistic effect of SAEW treatment showed intense anti-biofilm activity in decreasing cell density and impairing biofilm cell membranes.Global metabolic response of MRSA biofilms,treated by SAEW at 40℃,revealed the alterations of intracellular metabolites,including amino acids,organic acid,fatty acid,and lipid.Moreover,signaling pathways involved in amino acid metabolism,energy metabolism,nucleotide synthesis,carbohydrate metabolites,and lipid biosynthesis were functionally disrupted by the SAEW at 40℃treatment.As per our knowledge,this is the first research to uncover the potential mechanism of heated SAEW treatment against MRSA biofilm on food contact surface.
