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Research on Design Method of Dynamic Shop Floor Scheduling System Based on Human-computer Interaction
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作者 Songling TIAN Zhuke CAI +1 位作者 Xiaoqiang WU Xiaoqian QI 《Mechanical Engineering Science》 2025年第2期17-26,共10页
The shop floor dynamic scheduling system based on human-computer interaction is the use of computer-aided decision-making and human-computer interaction to solve the dynamic scheduling problem.A human-computer interac... The shop floor dynamic scheduling system based on human-computer interaction is the use of computer-aided decision-making and human-computer interaction to solve the dynamic scheduling problem.A human-computer interaction interface based on Gantt chart is designed,which can not only comprehensively and quantitatively represent the scheduling process and scheduling scheme,but also have friendly human-computer interaction performance.The data transmission and interaction architecture is constructed to realize the rapid response to shop floor disturbance events.A priority calculation algorithm integrating priority rules and dispatcher preference is proposed,which realizes the automatic calculation of priority for the dispatcher's reference and reduces theirburden.A man-machine interactive shop floor dynamic scheduling strategy is proposed.When solving the dynamic flexible job shop scheduling problem caused by machine tool breakdown and urgent order,the origin moments obtained by using this strategy are 0.4190 and 0.3703 respectively.As can be seen from the origin moment indicator,the dynamic shop floor scheduling system based on the human-computer interaction is efficient and reliable in solving dynamic scheduling problems,and related strategies of this system are also feasible and stable. 展开更多
关键词 human-computer interaction Dynamic scheduling Flexible shop floor scheduling Perturbation events
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A new human-computer interaction paradigm: Agent interaction model based on large models and its prospects
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作者 Yang LIU 《虚拟现实与智能硬件(中英文)》 2025年第3期237-266,共30页
This study examines the advent of agent interaction(AIx)as a transformative paradigm in humancomputer interaction(HCI),signifying a notable evolution beyond traditional graphical interfaces and touchscreen interaction... This study examines the advent of agent interaction(AIx)as a transformative paradigm in humancomputer interaction(HCI),signifying a notable evolution beyond traditional graphical interfaces and touchscreen interactions.Within the context of large models,AIx is characterized by its innovative interaction patterns and a plethora of application scenarios that hold great potential.The paper highlights the pivotal role of AIx in shaping the future landscape of the large model industry,emphasizing its adoption and necessity from a user's perspective.This study underscores the pivotal role of AIx in dictating the future trajectory of a large model industry by emphasizing the importance of its adoption and necessity from a user-centric perspective.The fundamental drivers of AIx include the introduction of novel capabilities,replication of capabilities(both anthropomorphic and superhuman),migration of capabilities,aggregation of intelligence,and multiplication of capabilities.These elements are essential for propelling innovation,expanding the frontiers of capability,and realizing the exponential superposition of capabilities,thereby mitigating labor redundancy and addressing a spectrum of human needs.Furthermore,this study provides an in-depth analysis of the structural components and operational mechanisms of agents supported by large models.Such advancements significantly enhance the capacity of agents to tackle complex problems and provide intelligent services,thereby facilitating a more intuitive,adaptive,and personalized engagement between humans and machines.The study further delineates four principal categories of interaction patterns that encompass eight distinct modalities of interaction,corresponding to twenty-one specific scenarios,including applications in smart home systems,health assistance,and elderly care.This emphasizes the significance of this new paradigm in advancing HCI,fostering technological advancements,and redefining user experiences.However,it also acknowledges the challenges and ethical considerations that accompany this paradigm shift,recognizing the need for a balanced approach to harness the full potential of AIx in modern society. 展开更多
关键词 interaction paradigm Agent interaction Large models
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Vision-Based Hand Gesture Recognition for Human-Computer Interaction——A Survey 被引量:2
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作者 GAO Yongqiang LU Xiong +4 位作者 SUN Junbin TAO Xianglin HUANG Xiaomei YAN Yuxing LIU Jia 《Wuhan University Journal of Natural Sciences》 CAS CSCD 2020年第2期169-184,共16页
Recently,vision-based gesture recognition(VGR)has become a hot research spot in human-computer interaction(HCI).Unlike other gesture recognition methods with data gloves or other wearable sensors,vision-based gesture ... Recently,vision-based gesture recognition(VGR)has become a hot research spot in human-computer interaction(HCI).Unlike other gesture recognition methods with data gloves or other wearable sensors,vision-based gesture recognition could lead to more natural and intuitive HCI interactions.This paper reviews the state-of-the-art vision-based gestures recognition methods,from different stages of gesture recognition process,i.e.,(1)image acquisition and pre-processing,(2)gesture segmentation,(3)gesture tracking,(4)feature extraction,and(5)gesture classification.This paper also analyzes the advantages and disadvantages of these various methods in detail.Finally,the challenges of vision-based gesture recognition in haptic rendering and future research directions are discussed. 展开更多
关键词 vision-based gesture recognition human-computer interaction STATE-OF-THE-ART feature extraction
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Risk identification and safety assessment of human-computer interaction in integrated avionics based on STAMP 被引量:1
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作者 ZHAO Changxiao LI Hao +2 位作者 ZHANG Wei DAI Jun DONG Lei 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第3期689-706,共18页
To solve the problem of risk identification and quantitative assessment for human-computer interaction(HCI)in complex avionics systems,an HCI safety analysis framework based on system-theoretical process analysis(STPA... To solve the problem of risk identification and quantitative assessment for human-computer interaction(HCI)in complex avionics systems,an HCI safety analysis framework based on system-theoretical process analysis(STPA)and cognitive reliability and error analysis method(CREAM)is proposed.STPACREAM can identify unsafe control actions and find the causal path during the interaction of avionics systems and pilot with the help of formal verification tools automatically.The common performance conditions(CPC)of avionics systems in the aviation environment is established and a quantitative analysis of human failure is carried out.Taking the head-up display(HUD)system interaction process as an example,a case analysis is carried out,the layered safety control structure and formal model of the HUD interaction process are established.For the interactive behavior“Pilots approaching with HUD”,four unsafe control actions and35 causal scenarios are identified and the impact of common performance conditions at different levels on the pilot decision model are analyzed.The results show that HUD's HCI level gradually improves as the scores of CPC increase,and the quality of crew member cooperation and time sufficiency of the task is the key to its HCI.Through case analysis,it is shown that STPACREAM can quantitatively assess the hazards in HCI and identify the key factors that impact safety. 展开更多
关键词 AVIONICS human-computer interaction(HCI) safety assessment system-theoretic accident model and process human reliability analysis
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Dynamic constraint and objective generation approach for real-time train rescheduling model under human-computer interaction 被引量:1
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作者 Kai Liu Jianrui Miao +2 位作者 Zhengwen Liao Xiaojie Luan Lingyun Meng 《High-Speed Railway》 2023年第4期248-257,共10页
Real-time train rescheduling plays a vital role in railway transportation as it is crucial for maintaining punctuality and reliability in rail operations.In this paper,we propose a rescheduling model that incorporates... Real-time train rescheduling plays a vital role in railway transportation as it is crucial for maintaining punctuality and reliability in rail operations.In this paper,we propose a rescheduling model that incorporates constraints and objectives generated through human-computer interaction.This approach ensures that the model is aligned with practical requirements and daily operational tasks while facilitating iterative train rescheduling.The dispatcher’s empirical knowledge is integrated into the train rescheduling process using a human-computer interaction framework.We introduce six interfaces to dynamically construct constraints and objectives that capture human intentions.By summarizing rescheduling rules,we devise a rule-based conflict detection-resolution heuristic algorithm to effectively solve the formulated model.A series of numerical experiments are presented,demonstrating strong performance across the entire system.Furthermore,theflexibility of rescheduling is enhanced through secondary analysis-driven solutions derived from the outcomes of humancomputer interactions in the previous step.This proposed interaction method complements existing literature on rescheduling methods involving human-computer interactions.It serves as a tool to aid dispatchers in identifying more feasible solutions in accordance with their empirical rescheduling strategies. 展开更多
关键词 Real-time train rescheduling human-computer interaction Rule-based heuristic algorithm Secondary rescheduling
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Identification and distribution of 13003 landslides in the northwest margin of Qinghai-Tibet Plateau based on human-computer interaction remote sensing interpretation
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作者 Wei Wang Yuan-dong Huang +8 位作者 Chong Xu Xiao-yi Shao Lei Li Li-ye Feng Hui-ran Gao Yu-long Cui Shuai Wu Zhi-qiang Yang Kai Ma 《China Geology》 CAS CSCD 2024年第2期171-187,共17页
The periphery of the Qinghai-Tibet Plateau is renowned for its susceptibility to landslides.However,the northwestern margin of this region,characterised by limited human activities and challenging transportation,remai... The periphery of the Qinghai-Tibet Plateau is renowned for its susceptibility to landslides.However,the northwestern margin of this region,characterised by limited human activities and challenging transportation,remains insufficiently explored concerning landslide occurrence and dispersion.With the planning and construction of the Xinjiang-Xizang Railway,a comprehensive investigation into disastrous landslides in this area is essential for effective disaster preparedness and mitigation strategies.By using the human-computer interaction interpretation approach,the authors established a landslide database encompassing 13003 landslides,collectively spanning an area of 3351.24 km^(2)(36°N-40°N,73°E-78°E).The database incorporates diverse topographical and environmental parameters,including regional elevation,slope angle,slope aspect,distance to faults,distance to roads,distance to rivers,annual precipitation,and stratum.The statistical characteristics of number and area of landslides,landslide number density(LND),and landslide area percentage(LAP)are analyzed.The authors found that a predominant concentration of landslide origins within high slope angle regions,with the highest incidence observed in intervals characterised by average slopes of 20°to 30°,maximum slope angle above 80°,along with orientations towards the north(N),northeast(NE),and southwest(SW).Additionally,elevations above 4.5 km,distance to rivers below 1 km,rainfall between 20-30 mm and 30-40 mm emerge as particularly susceptible to landslide development.The study area’s geological composition primarily comprises Mesozoic and Upper Paleozoic outcrops.Both fault and human engineering activities have different degrees of influence on landslide development.Furthermore,the significance of the landslide database,the relationship between landslide distribution and environmental factors,and the geometric and morphological characteristics of landslides are discussed.The landslide H/L ratios in the study area are mainly concentrated between 0.4 and 0.64.It means the landslides mobility in the region is relatively low,and the authors speculate that landslides in this region more possibly triggered by earthquakes or located in meizoseismal area. 展开更多
关键词 LANDSLIDES human-computer interaction interpretation Landslide database Spatial distribution Earthquake RAINFALL Human engineering activity Qinghai-Tibet Plateau Geological hazards survey engineering
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Reform of Human-Computer Interaction Course based on Mobile Application Interaction Design
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作者 Siyang Lu Xiang Wei 《计算机教育》 2020年第12期122-125,共4页
With the popularity of new intelligent mobile devices in people’s lives,the development of mobile applications has paid increasing attention to the interactive experience of users.As the content of traditional Human-... With the popularity of new intelligent mobile devices in people’s lives,the development of mobile applications has paid increasing attention to the interactive experience of users.As the content of traditional Human-Computer Interaction(HCI)course and teaching material is out of date,it cannot meet the needs of mobile application interaction design and enterprises for students.Therefore,we need a new generation HCI course based on intelligent mobile devices to study the relationship between users and systems.The HCI course not only teaches students HCI theory and model,but also needs to cultivate students’interaction-oriented design practical ability.This paper proposes a set of HCI teaching material design and teaching methods for improving HCI class quality on mobile application interaction design,so as to make students more suitable for the employment requirements of enterprises. 展开更多
关键词 human-computer interaction software engineering mobile application interaction design
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An Architecture Supporting Intelligent Mobile Healthcare Using Human-Computer Interaction HCI Principles 被引量:1
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作者 Mesfer Alrizq Shauban Ali Solangi +3 位作者 Abdullah Alghamdi Muhammad Ali Nizamani Muhammad Ali Memon Mohammed Hamdi 《Computer Systems Science & Engineering》 SCIE EI 2022年第2期557-569,共13页
Recent advancements in the Internet of Things IoT and cloud computing have paved the way for mobile Healthcare(mHealthcare)services.A patient within the hospital is monitored by several devices.Moreover,upon leaving t... Recent advancements in the Internet of Things IoT and cloud computing have paved the way for mobile Healthcare(mHealthcare)services.A patient within the hospital is monitored by several devices.Moreover,upon leaving the hospital,the patient can be remotely monitored whether directly using body wearable sensors or using a smartphone equipped with sensors to monitor different user-health parameters.This raises potential challenges for intelligent monitoring of patient's health.In this paper,an improved architecture for smart mHealthcare is proposed that is supported by HCI design principles.The HCI also provides the support for the User-Centric Design(UCD)for smart mHealthcare models.Furthermore,the HCI along with IoT's(Internet of Things)5-layered architecture has the potential of improving User Experience(UX)in mHealthcare design and help saving lives.The intelligent mHealthcare system is supported by the IoT sensing and communication layers and health care providers are supported by the application layer for the medical,behavioral,and health-related information.Health care providers and users are further supported by an intelligent layer performing critical situation assessment and performing a multi-modal communication using an intelligent assistant.The HCI design focuses on the ease-of-use,including user experience and safety,alarms,and error-resistant displays of the end-user,and improves user's experience and user satisfaction. 展开更多
关键词 Human computer interaction mhealthcare user-centric design sensor network nternet-of-things
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Design and Implementation of the Image Interactive System Based on Human-Computer Interaction
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作者 Shanwei Song Yuting Wu Fang Zhang 《Intelligent Information Management》 2010年第5期334-337,共4页
Based on the traditional Human-Computer Interaction method which is mainly touch input system, the way of capturing the movement of people by using cameras is proposed. This is a convenient technique which can provide... Based on the traditional Human-Computer Interaction method which is mainly touch input system, the way of capturing the movement of people by using cameras is proposed. This is a convenient technique which can provide users more experience. In the article, a new way of detecting moving things is given on the basis of development of the image processing technique. The system architecture decides that the communication should be used between two different applications. After considered, named pipe is selected from many ways of communication to make sure that video is keeping in step with the movement from the analysis of the people moving. According to a large amount of data and principal knowledge, thinking of the need of actual project, a detailed system design and realization is finished. The system consists of three important modules: detecting of the people's movement, information transition between applications and video showing in step with people's movement. The article introduces the idea of each module and technique. 展开更多
关键词 human-computer interaction IMAGE Processing MOVING OBJECT Detection COMMUNICATION Response
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Design of hybrid variable stiff ness human-computer interaction contact unit module based on granular jamming
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作者 Chao Gao Chang Wang +4 位作者 Jianhua Zhang Hui Li Yufei Hao Kexiang Li Jianjun Zhang 《Chinese Journal of Mechanical Engineering》 2026年第1期423-431,共9页
Existing rehabilitation exoskeleton robots suffer from poor compatibility with the human limb coupling method,large internal power loss,and poor wearable performance,which seriously affect the rehabilitation ability o... Existing rehabilitation exoskeleton robots suffer from poor compatibility with the human limb coupling method,large internal power loss,and poor wearable performance,which seriously affect the rehabilitation ability of these robots.Therefore,this study proposes a variable stiffness humancomputer interaction contact unit module(VSHCUM)based on the granular jamming mechanism.It is characterized by a double-layer chamber structure:the inner layer is a granular chamber,and the outer layer is an air chamber.The interaction force is transmitted by embedding a rigid support in the inner layer.Unlike the common flexible-belt interactive contact unit,when the exoskeleton is bound to the patient's limb,vSHCUM can realize adaptive fitting of the patient's limb shape using the pressure change in the double-chamber structure.Simultaneously,by adjusting the vacuum level of the granular chamber,the stiffness of the interactive contact unit can be adjusted by a factor of more than five,and the internal work loss caused by self-pulling deformation during the auxiliary force transfer process can be reduced. 展开更多
关键词 Granular jamming Variable stiffness human-computer interaction Human-machine compatibility
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Virtual Reality Integrated Human-Computer InteractionSystem Based on Ultraleap 3Di Hand Gestures Recognition
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作者 Chujie He Xiangyu Zhou +5 位作者 Jiarui Zhang Jing Luo Yahong Chen Xiaoli Liu Shifeng Ma Junjie Sun 《IET Cyber-Systems and Robotics》 2025年第4期65-79,共15页
Gesture recognition is a key task in the field of human-computer interaction(HCI).To solve the problems of low accuracy andpoor real-time performance in the recognition process,this paper designs a HCI system based on... Gesture recognition is a key task in the field of human-computer interaction(HCI).To solve the problems of low accuracy andpoor real-time performance in the recognition process,this paper designs a HCI system based on gesture recognition.This paperutilises the Ultraleap 3Di to collect the dynamic gesture dataset for the defined interaction gestures,and the high-precisiondevice guarantees data collection.This paper constructs a framework incorporating the advantages of convolutional neuralnetworks(CNNs)and long short-term memory networks(LSTM)using noncontact gesture interaction as the medium ofhuman-computer collaboration.The framework utilises CNN to perform feature extraction on the input frame information.Then,the extracted feature sequences are fed into LSTM to process the timing information,which is very effective in classifyingand recognising the defined dynamic gestures.Finally,a HCI system based on gesture recognition is designed.Based on theUnity3D platform,the UR5 robotic arm was modelled and the cyclic coordinate descent(CCD)algorithm was applied to solvethe inverse kinematics,successfully realising the semantic control of gestures on the UR5 robotic arm.The experiment verifiesthat the CNN-LSTM network can ensure the real-time performance of the whole system and the effectiveness and reliability ofthe gesture interaction system based on Ultraleap 3Di. 展开更多
关键词 convolutional neural network dynamic model human robot interaction neural network-based
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Woven fabric triboelectric nanogenerators for human-computer interaction and physical health monitoring 被引量:1
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作者 Yu Miao Mengjuan Zhou +7 位作者 Jia Yi Yanyan Wang Guangjin Tian Hongxia Zhang Wenlong Huang Wenhao Wang Ronghui Wu Liyun Ma 《Nano Research》 SCIE EI CSCD 2024年第6期5540-5548,共9页
Triboelectric nanogenerator(TENG)converts mechanical energy into valuable electrical energy,offering a solution for future energy needs.As an indispensable part of TENG,textile TENG(T-TENG)has incredible advantages in... Triboelectric nanogenerator(TENG)converts mechanical energy into valuable electrical energy,offering a solution for future energy needs.As an indispensable part of TENG,textile TENG(T-TENG)has incredible advantages in harvesting biomechanical energy and physiological signal monitoring.However,the application of T-TENG is restricted,partly because the fabric structure parameter and structure on T-TENG performance have not been fully exploited.This study comprehensively investigates the effect of weaving structure on fabric TENGs(F-TENGs)for direct-weaving yarn TENGs and post-coating fabric TENGs.For direct-weaving F-TENGs,a single-yarn TENG(Y-TENG)with a core-sheath structure is fabricated using conductive yarn as the core layer yarn and polytetrafluoroethylene(PTFE)filaments as the sheath yarn.Twelve fabrics with five different sets of parameters were designed and investigated.For post-coating F-TENGs,fabrics with weaving structures of plain,twill,satin,and reinforced twill were fabricated and coated with conductive silver paint.Overall,the twill F-TENGs have the best electrical outputs,followed by the satin F-TENGs and plain weave F-TENGs.Besides,the increase of the Y-TENG gap spacing was demonstrated to improve the electrical output performance.Moreover,T-TENGs are demonstrated for human-computer interaction and self-powered real-time monitoring.This systematic work provides guidance for the future T-TENG’s design. 展开更多
关键词 single-yarn triboelectric nanogenerators woven fabric triboelectric nanogenerators fabric weaving structures and parameters human-computer interaction physical health monitoring
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Intelligent human-computer interactive training assistant system for rail systems 被引量:1
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作者 Yuexuan Li Junhua Chen +1 位作者 Xiangyong Luo Han Zheng 《High-Speed Railway》 2025年第1期64-77,共14页
In recent years,railway construction in China has developed vigorously.With continuous improvements in the highspeed railway network,the focus is gradually shifting from large-scale construction to large-scale operati... In recent years,railway construction in China has developed vigorously.With continuous improvements in the highspeed railway network,the focus is gradually shifting from large-scale construction to large-scale operations.However,several challenges have emerged within the high-speed railway dispatching and command system,including the heavy workload faced by dispatchers,the difficulty of quantifying subjective expertise,and the need for effective training of professionals.Amid the growing application of artificial intelligence technologies in railway systems,this study leverages Large Language Model(LLM)technology.LLMs bring enhanced intelligence,predictive capabilities,robust memory,and adaptability to diverse real-world scenarios.This study proposes a human-computer interactive intelligent scheduling auxiliary training system built on LLM technology.The system offers capabilities including natural dialogue,knowledge reasoning,and human feedback learning.With broad applicability,the system is suitable for vocational education,guided inquiry,knowledge-based Q&A,and other training scenarios.Validation results demonstrate its effectiveness in auxiliary training,providing substantial support for educators,students,and dispatching personnel in colleges and professional settings. 展开更多
关键词 High-speed railway Dispatch training assistance Large language model human-computer interactive training assistant system Reinforcement learning
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A survey of panel aeroelasticity in shock-dominated flow:Perspectives from fluid-structure interactions and shock wave-boundary layer interactions
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作者 Aiming SHI Yiwen HE 《Chinese Journal of Aeronautics》 2026年第1期210-229,共20页
As a multidisciplinary phenomenon,panel aeroelasticity in shock-dominated flow is featured by two primary interactions:Fluid-Structure Interactions(FSIs)and Shock-Boundary Layer Interactions(SBLIs).The former raises s... As a multidisciplinary phenomenon,panel aeroelasticity in shock-dominated flow is featured by two primary interactions:Fluid-Structure Interactions(FSIs)and Shock-Boundary Layer Interactions(SBLIs).The former raises structural concerns,and the latter is of aerodynamic interest.Thus,panel aeroelasticity in shock-dominated flow represents a vital topic for the development and optimization of supersonic vehicles and propulsion systems.This review systematically summarizes recent advances in the methodologies applied to capture structural and fluid dynamics,including theoretical models,numerical simulations,and wind tunnel experiments.The application of data-driven modal decomposition,an advanced technique to extract physically crucial features,on the topic is introduced.From the perspective of FSIs,the distinctive aeroelastic behaviors in shock-dominated flow,including hysteresis phenomena and nonlinear responses,are highlighted.From the perspective of SBLIs,the modifications in their spatial and temporal characteristics imposed by the aeroelastic responses are emphasized.Motivated by the interaction between the shock waves and structural response,different strategies have been proposed to implement aeroelastic suppression and shock control,which have the potential to enhance structural safety and aerodynamic performance in the next generation of high-speed flight vehicles. 展开更多
关键词 Aeroelasticity Fluid structure interaction Modal decomposition Shock boundary layer interactions Shock waves
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Host-vip interaction mediated low-shrinkage photosensitive positioning adhesive
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作者 Zhao Liu Junjian Xie +3 位作者 Xiaoming Ren Muhammad Tahir Shixin Fa Qiuyu Zhang 《Chinese Chemical Letters》 2026年第2期501-504,共4页
As a common electronic adhesive,ultraviolet(UV)curing polyurethane acrylate adhesive has both flexibility and wear resistance of polyurethane,excellent weather resistance and optical properties of acrylate.Despite the... As a common electronic adhesive,ultraviolet(UV)curing polyurethane acrylate adhesive has both flexibility and wear resistance of polyurethane,excellent weather resistance and optical properties of acrylate.Despite the extensive applications,it is still difficult to solve the problems caused by the shrinkage of adhesive.Here,a new type of photosensitive adhesive for bonding electronic components based on supramolecular interaction was designed and synthesized.The supramolecular interaction of cyclodextrin and adamantane moieties introduced into the adhesive polymer entitles the viscosity of the adhesive to rise rapidly during use,thereby preventing adhesive loss and dislocation of electronic components.UV light could further cure the adhesive and position the electronic components.The adhesive shrunk<2%when cured by UV light,so it can be used for electronic packaging and high-resolution,defect-free lithography. 展开更多
关键词 ADHESIVE Host-vip interaction UV-CURING Low-shrinkage LITHOGRAPHY
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Characterization of the interaction between human cytochrome c and transfer RNAphe
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作者 Guangqing Zhang Jianhua Zhan +4 位作者 Xin Chai Bin Jiang Maili Liu Xu Zhang Danyun Zeng 《Magnetic Resonance Letters》 2026年第1期1-12,共12页
Cytochrome c(cyt c)is released from mitochondria into the cytosol upon apoptotic stimulation,ultimately triggering programmed cell death.Recent studies have revealed that transfer RNA(tRNA)interacts with cyt c,impedin... Cytochrome c(cyt c)is released from mitochondria into the cytosol upon apoptotic stimulation,ultimately triggering programmed cell death.Recent studies have revealed that transfer RNA(tRNA)interacts with cyt c,impeding the formation of the apoptosome complex and thereby suppressing apoptosis.To elucidate the molecular mechanism underlying the interaction between cyt c and tRNA,nuclear magnetic resonance(NMR)-based chemical shift perturbation and intensity analysis were employed to characterize the binding interface between cyt c and tRNAphe.The findings demonstrate that cyt c primarily engages with tRNAphe through its 70–85Ω-loop and N-terminalα-helix.This interaction sterically hinders the accessibility of small molecules,such as H_(2)O_(2),to the hydrophobic pocket of cyt c,consequently attenuating its peroxidase activity.Furthermore,oxidative modification of cyt c,particularly the carbonylation of positively charged lysine residues,weakens this interaction. 展开更多
关键词 interaction NMR Cytochrome c TRNA Oxidative modification
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Fluid-structure interaction mechanism and theoretical models to predict lift and deformation for a flexible dynamic plate
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作者 Yutian CAO Lihao FENG +1 位作者 Yan LIANG Peijun CHENG 《Science China(Technological Sciences)》 2026年第2期127-144,共18页
In bio-inspired flapping-wing flight,lift generation and flexible deformation are intrinsically coupled.Thus,an experimental study is conducted to reveal the fluid-structure interaction mechanism for a flexible plate ... In bio-inspired flapping-wing flight,lift generation and flexible deformation are intrinsically coupled.Thus,an experimental study is conducted to reveal the fluid-structure interaction mechanism for a flexible plate undergoing pitching and plunging motion,and theoretical models are proposed to predict either lift or deformation based on a series of simplifying assumptions.It is indicated that flexible plates can effectively reduce the amplitude of lift and pitching moment coefficients during dynamic stall,with increased flexibility leading to higher load reduction.To investigate the effect of plate flexibility on lift,a definition of effective angle of attack is proposed,incorporating the pitching and plunging motion and chordwise deformation of the flexible plate,which can reduce the hysteresis effect of the lift coefficient during dynamic stall.As a consequence,a theoretical model is developed to predict lift based on observed motion and deformation.On the other hand,another theoretical model is developed to predict flexible-plate deformation utilizing aerodynamic forces,revealing the effect of leading-edge vortex evolution on passive deformation.The influence of kinematic parameters,including the maximum effective angle of attack,reduced frequency,and Strouhal number,on the aerodynamic forces is further studied.Compared with the rigid plate,flexible plates exhibit lower sensitivity of aerodynamic forces to changes in kinematic parameters due to their inherent compliance and resulting deformation.The proposed theoretical models can serve as a reference for aerodynamic and deformation prediction in bio-inspired flexible structures. 展开更多
关键词 fluid-structure interaction vortex dynamics flexible wing
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Interactions between selenium-containing peptide Ser-Phe-Gln-SeM and intestinal microbiota:implications for antioxidant mechanism and host metabolism
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作者 Xing Zhang Yucheng Xiang +2 位作者 Tao Hou Chenyang Lu Shaohua Huang 《Food Science and Human Wellness》 2026年第1期110-124,共15页
The antioxidant activity of selenium-containing soybean peptides(SePPs)has been previously demonstrated,despite their limited absorption in the small intestine.This study investigates the antioxidant mechanism of a se... The antioxidant activity of selenium-containing soybean peptides(SePPs)has been previously demonstrated,despite their limited absorption in the small intestine.This study investigates the antioxidant mechanism of a selenium-containing tetrapeptide,Ser-Phe-Gln-SeM(SFQSeM),identified from SePPs,with particular emphasis on its interaction with the intestinal microbiota and its role in modulating host antioxidant defenses.The effects of SFQSeM were evaluated in a D-galactose-induced oxidative stress model and an antibiotictreated mouse model.SFQSeM supplementation significantly reduced the oxidative stress in D-galactosetreated mice.It also promoted the growth of beneficial bacteria and increased the levels of acetate,butyrate and lactate in the intestine(P<0.05).In the antibiotic-treated mouse model,depletion of the intestinal microbiota significantly reduced hepatic glutathione peroxidase(GSH-Px)activity(26.6%)and glutathione peroxidase 1(GPx-1)expression(48.77%)compared to normal mice supplemented with SFQSeM(P<0.05).In contrast to Na_(2)SeO_(3)and selenomethionine,SFQSeM effectively restored the diversity of the intestinal microbiota disrupted by antibiotics.Lactobacillus,Lachnospiraceae_NK4A136_group,and Muribaculaceae were identified as predominant bacteria in the SFQSeM group,and were strongly associated with increased hepatic GSH-Px activity and GPx-1 mRNA expression(P<0.05).In conclusion,intestinal microbiota enhances the antioxidant efficacy of SFQSeM by modulating microbial composition,producing active metabolites,and converting SFQSeM into a bioactive form of selenium. 展开更多
关键词 Selenium-containing peptides Antioxidant mechanism Intestinal microbiota Host interaction
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Mechanical behavior and damage constitutive model of silty mudstone under thermo-hydro-mechanical interactions
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作者 ZENG Ling CHENG Hui +6 位作者 SONG Jianping XIONG Jianping ZHANG Hongri CHEN Jingcheng WANG Wenguang LI Youjun LIU Jie 《Journal of Mountain Science》 2026年第1期434-452,共19页
Understanding the deterioration behaviors and mechanisms of rocks under thermo-hydromechanical(THM)interactions is crucial for mitigating slope instability.In this study,the physicomechanical properties of silty mudst... Understanding the deterioration behaviors and mechanisms of rocks under thermo-hydromechanical(THM)interactions is crucial for mitigating slope instability.In this study,the physicomechanical properties of silty mudstone subjected to THM interactions were investigated by triaxial tests.The underlying micro-mechanisms were revealed using microscopic tests.The triaxial test results indicate that the strength parameters of silty mudstone decrease by 89.50%(deformation modulus),78.15%(peak strength),70.58%(cohesion),and 48.65%(friction angle)under 16 THM cycles,a load of 300 kPa,and alternating between 0℃water immersion and 60℃drying.The SEM test results indicate that the deterioration of silty mudstone strength primarily results from hydrothermal-expansion softening and cracking driven by the TLHM interactions.The specimens manifest shear failure under confining pressure exceeding 140 kPa.Furthermore,a new constitutive model considering hydrothermalexpansion strain and non-linear deformation characteristics was developed.The discrepancy between the experimentally measured peak strength and the damage constitutive model prediction remains below 5%.The proposed model is verified to be in satisfactory agreement with the experimental results.The self-designed THM apparatus overcomes the limitations of traditional investigations,enabling simultaneous consideration of thermal,hydraulic,and mechanical interactions. 展开更多
关键词 Silty mudstone THM interactions Mechanical properties Damage constitutive model
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Toughening Recycled Waste Rubbers by Dynamic Interactions for Stress Deconcentration
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作者 Hao-Jia Guo Zhou-Liang Wu +1 位作者 Shuang-Quan Liao Ming-Chao Luo 《Chinese Journal of Polymer Science》 2026年第1期234-241,I0017,共9页
Recycling of waste rubber(WR)is crucial for the sustainable development of the rubber industry.The enhancement of interfacial interactions is the main strategy for waste polymer recycling.However,there is a lack of me... Recycling of waste rubber(WR)is crucial for the sustainable development of the rubber industry.The enhancement of interfacial interactions is the main strategy for waste polymer recycling.However,there is a lack of methods for enhancing the interfacial interactions for WR recycling because WR contains abundant inert C―H bonds.Herein,we designed thioctic acid inverse vulcanization copolymers to endow recycled WR with dynamic disulfide interfacial interactions,significantly improving the mechanical properties of recycled WR.These disulfide interfacial interactions among the recycled WR tend to exchange,which dramatically increases the fractocohesive length and prevents stress concentration near the crack tips.When recycled WR is subjected to external stress,the loads are redistributed across a broad region of adjacent regions instead of being concentrated on a limited length scale,which resists crack propagation.This work effectively recycled WR,providing a strategy for solvent-free reaction-derived inverse vulcanization copolymers to improve the toughness of WR recycling. 展开更多
关键词 Waste rubbers RECYCLING Inverse vulcanization copolymers Dynamic interactions Stress deconcentration
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