Introduction The Caspian-Black Sea-Mediterranean Corridor["CORRIDOR"]encompasses the Eurasian intercontinental basins of the Caspian,Black,Marmara,Aegean,and Eastern Mediterranean(Levantine)seas with their c...Introduction The Caspian-Black Sea-Mediterranean Corridor["CORRIDOR"]encompasses the Eurasian intercontinental basins of the Caspian,Black,Marmara,Aegean,and Eastern Mediterranean(Levantine)seas with their connecting straits and coasts.Periodic connection/isolation of the basins during the Quaternary predetermined their specific environmental conditions and particular hydrologic regimes,and thus,the area,and especially the Ponto-Caspian,represents a“natural laboratory”to study the responses of semi-isolated and isolated basins to climate changes.展开更多
Using cytotoxicity and thymidine uptake assays, we investigated the effects of human recombinant in-terleukin-2 (rIL-2) on the induction of lympholine-activated killer (LAK) activity and cellular proliferation in sple...Using cytotoxicity and thymidine uptake assays, we investigated the effects of human recombinant in-terleukin-2 (rIL-2) on the induction of lympholine-activated killer (LAK) activity and cellular proliferation in splenocytes and thymocytes from human fetuses (18-22 weeks). We observed that fetal splenocytes and thymocytes incubated with low doses of rIL-2 (10-100 U ml) developed broad antitumor activity (LAK activity) although the kinetics and magnitudes of the responses were different. It indicated the LAK precursors are present in fetal spleen and thymus. Further, rIL-2 induced a strong proliferative response in splenocytes, but not in thymocytes. On the basis of the findings, we conclude that the responses of fetal splenocytes and thymocytes to IL-2 are different.展开更多
The 2030 Agenda for Sustainable Development provides a core framework and platform for global development,mainly characterized by the incorporation of human rights protection responsibilities and explicit acknowledgme...The 2030 Agenda for Sustainable Development provides a core framework and platform for global development,mainly characterized by the incorporation of human rights protection responsibilities and explicit acknowledgment of the shared role of development and human rights in safeguarding human dignity and well-being.Human rights responsibilities require states to prioritize human development within their development agenda,achieve human rights through development,and adhere to human rights principles and standards.Integrating human rights responsibilities into the development agenda not only makes development more comprehensive but also provides legal constraints and monitoring mechanisms for the implementation of development goals.The 2030 Agenda for Sustainable Development redefines the relationship between development and human rights and is thus closely aligned with China’s practice of advancing sustainable development and human rights protection simultaneously.Guided by the people-centered development philosophy and new development philosophy,China has accomplished the historic tasks of the fight against poverty and the building of a moderately prosperous society in all respects,while significantly enhancing human rights protection.These achievements have provided a unique country-specific experience of“promoting human rights through development”for the implementation of sustainable development goals.展开更多
To explore the thermal responses under the non-thermal equilibrium cold environmental conditions,a laboratory study was conducted in climate chamber.The local skin temperatures and thermal sensation of 20 subjects wer...To explore the thermal responses under the non-thermal equilibrium cold environmental conditions,a laboratory study was conducted in climate chamber.The local skin temperatures and thermal sensation of 20 subjects were recorded at 10 min intervals for 90 min under air temperatures of 7.4,9.1,11 and 15 °C.The results show that both local skin temperatures and mean skin temperature decrease not only with the drop of ambient air temperature but also with the exposure time.Local thermal sensation and overall the thermal sensation have the similar temperature-varying and time-varying characteristics.Predicted mean vote(PMV) model cannot correctly predict the thermal sensation under non-thermal equilibrium cold environment.The correlation between local thermal sensation and local skin temperatures shows that thermal sensation is closely related to skin temperature.Skin temperature is an effective indicator of thermal sensation.A linear relationship model between overall thermal sensation and mean skin temperature,considering both ambient temperature and exposure time,was established in the non-thermal equilibrium cold environment,which makes the evaluation of thermal sensation more objective.展开更多
The aim of this study is to create alternative approaches to predict human response to ground vibration.Site measurements were conducted in an urban quarry.The multiple discriminant analysis technique was used to deve...The aim of this study is to create alternative approaches to predict human response to ground vibration.Site measurements were conducted in an urban quarry.The multiple discriminant analysis technique was used to develop classification models.The measured ground vibration values were grouped based on the limit values appearing in the literature.Two classification models were created to predict human response to ground vibration.In addition,classical predictor equations were developed to compare to the classification models.The best equations were chosen considering several error measures.All the models were tested on the independent data.The prediction accuracy of the discriminant analysis models is quite promising.Nearly eighty-nine percent of the test data were correctly classified.The classification models have a combined structure.The results of the models can be directly presented to the neighbors of the studied quarry.The models are not complex.They do not require additional software or information to practice and can be easily used by site engineers.展开更多
The extraterritorial application of international human rights conventions is the legal basis for states to regulate the extraterritorial human rights obligations of transnational corporations.In recent years,it has b...The extraterritorial application of international human rights conventions is the legal basis for states to regulate the extraterritorial human rights obligations of transnational corporations.In recent years,it has been increasingly challenged by the new trend of the United Nations governing the human rights responsibilities of transnational corporations.A study of existing international rules and practices shows that the extraterritorial application of international human rights conventions depends on the extraterritorial jurisdiction of the States Parties,which mainly includes the actual control over extraterritorial territories and individuals as well as the execution of authority outside the territories.In view of the above,if human rights violations by individuals or transnational corporations occur in areas outside their home territories or are authorized and orchestrated by the home state,the home state shall bear the corresponding human rights responsibilities.Given the restrictive scope of the abovementioned extraterritorial application of international human rights conventions,the international cooperation obligation and the"do no harm"principle may become a new legal basis for states to fulfill their extraterritorial human rights obligations in the future,thereby expanding the basis for the extraterritorial application of international human rights conventions to deal with more serious issues of human rights violations by transnational corporations.However,on the whole,the current identification and codification of states regulating the extraterritorial human rights obligations of transnational corporations should respect the existing rules of international human rights law and should not add any new human rights obligations on states.展开更多
This paper deals with mathematical study of diffusive fluid transport and distri- bution in human dermal parts. It accounts the intracellular fluid which continuously flows through the skin shells in order to maintain...This paper deals with mathematical study of diffusive fluid transport and distri- bution in human dermal parts. It accounts the intracellular fluid which continuously flows through the skin shells in order to maintain fluid balance within the body. A mathematical model is envisaged for this process and the finite element method （FEM） is employed to calculate the concentration of the fluid at different skin layers. This estimation is analyzed in relation with other parameters of the tissue medium and the atmosphere.展开更多
A primary human renal cell carcinoma was developed as a xenograft (NT-25) and maintained by serial transplantation in nude mice. The effect of UFT on this neogrowth was tested and evaluated as well its distribution in...A primary human renal cell carcinoma was developed as a xenograft (NT-25) and maintained by serial transplantation in nude mice. The effect of UFT on this neogrowth was tested and evaluated as well its distribution in the animal tissues. The concentration of UFT was higher in tumor tissues than that in other tissues and in the animal experimentation UFT was found to be effective on human renal cell carcinoma.展开更多
As China’s overseas investment and business operations continue to expand,the issue of human rights risks faced by Chinese transnational corporations abroad has attracted sustained attention from society.In recent ye...As China’s overseas investment and business operations continue to expand,the issue of human rights risks faced by Chinese transnational corporations abroad has attracted sustained attention from society.In recent years,China has enacted a series of laws,regulations,and policies to better regulate the overseas business conduct of transnational corporations,urging them to respect the human rights of the people in host countries and fulfill their social responsibilities to achieve sustainable development.Meanwhile,China has actively participated in the formulation of the Legally Binding Instrument on Activities of Transnational Corporations and Other Business Enterprises in International Human Rights Law,providing a Chinese solution to promote global governance of transnational corporations.However,in practice,the lack of institutional mechanisms,systems,and industry rules to supervise and guide transnational enterprises in fulfilling their human rights responsibilities,as well as the limited awareness of human rights risks among these enterprises,have resulted in ongoing human rights risks in their overseas business operations,particularly regarding labor rights and environmental rights.In response,China should take its national conditions into consideration and focus on the development trends of human rights issues in the business sector at the international level.Drawing on the experiences of other countries,China should explore and establish institutional and practical measures to regulate the human rights responsibilities of transnational enterprises through legislation,administration,and judiciary actions,in order to address the risks and challenges faced by Chinese enterprises in foreign investments and contribute to the sustainable development of the world and global human rights governance.展开更多
Chromogenic windows enable both energy-saving and daylighting regulation.However,the human response to the luminous environment affected by them is difficult to test,since their features of dynamic change and tinting ...Chromogenic windows enable both energy-saving and daylighting regulation.However,the human response to the luminous environment affected by them is difficult to test,since their features of dynamic change and tinting automatically.This study explores the research methods,including experimental design and statistical analysis,by literature review and an experiment demonstration.The results show that a proper size of the test room is significant to obtain desired data,and the advanced VR technologies have the potential to be applied for testing these dynamic variables.Bayesian approaches are recommended to be tried and get more accurate interference about the experimental results.展开更多
With the adoption of the"Legally Binding Instrument to Regulate,in International Human Rights Law,the Activities of Transnational Corporations and other Business Enterprises"and its revised draft,the codific...With the adoption of the"Legally Binding Instrument to Regulate,in International Human Rights Law,the Activities of Transnational Corporations and other Business Enterprises"and its revised draft,the codification of the human rights responsibilities of transnational corporations has entered a new era The instrument aims to supplement the shortcomings of transnational corporations in fulfilling their human rights responsibilities by strengthening the obligations of states and to improve the host country’s inadequate remedies for human rights violations by establishing extraterritorial human rights jurisdiction of home countries But the instrument has encountered various challenges because the human rights obligations and legal responsibilities of states go beyond the current domestic human rights systems and impact the existing theories and practices of international human rights law In order to resolve the differences among countries,the future codification of the instrument should be based on existing domestic and international legal systems and practices striking a balance between the interests of developing and developed countries,taking into account the objectives of both the fair treatment of transnational corporations and human rights protection,to promote the regulatory effect of the human rights responsibilities of transnational corporations.展开更多
In this study, the immuno-response of recombinant hCG-β and natural hCGβ was comparatively investigated by using Freund's adjuvant. The results showed that, the properties and merits of the antibodies elicited b...In this study, the immuno-response of recombinant hCG-β and natural hCGβ was comparatively investigated by using Freund's adjuvant. The results showed that, the properties and merits of the antibodies elicited by both kinds of hCG-β were similar. The antisera had high affinity for binding with hCG (Kαγβ≈5.86×108/mol/L, Kαβ≈8.18×108/mol/L), and were found to be effective in inhibiting the binding of 125I-hCG to receptors in rat testes. Results also indicated that, similar to the antisera induced by natural hCG-β, the recombinant hCG-β induced antisera had capacity of neutralizing the biological activities of hCG. Recombinant hCG-β could be used as an immunogen for contraceptive vaccine.展开更多
On July 22, 2014, the second group of national human rights education and train- ing bases was announced,increasing the number of national bases from the previous three to a total of eight, which reflects the advancem...On July 22, 2014, the second group of national human rights education and train- ing bases was announced,increasing the number of national bases from the previous three to a total of eight, which reflects the advancement of human rights education and ~aining in China and has far-reaching significance.展开更多
An analysis of nearly 250 years of flood records on the river Eden at Appleby-in-Westmorland has enabled a flood frequency relationship to be established. The most severe floods were in the late 18th and early 19th ce...An analysis of nearly 250 years of flood records on the river Eden at Appleby-in-Westmorland has enabled a flood frequency relationship to be established. The most severe floods were in the late 18th and early 19th century. With such a long history of flooding, some remedial measures would have been expected but the local people have, to some extent, adapted to the flood hazard by means of temporary and permanent flood proofing methods such as a cemented board across a doorway and removable flood boards. These measures were overwhelmed during the 2015 flood, as were the flood gates installed by the Environment Agency in 1998. A higher level of protection from floods at Appleby is called for.展开更多
The scientific environmental ethics plays a key role in the recognition of the human-environment interactions. Modern environmental ethics is the philosophical re-thinking of modern human race environmental behavior. ...The scientific environmental ethics plays a key role in the recognition of the human-environment interactions. Modern environmental ethics is the philosophical re-thinking of modern human race environmental behavior. The development of environmental ethics theory, as well as its application in reality, determines the viewpoints of environmental ethics. Sustainable development implies harmony on human-environment interactions and inter-generation responsibility, with emphasis on a harmonious relationship among population, resources, environment and development, so as to lay a sustainable and healthy foundation of resources and environment for future generations. The harmonious society construction in China that is raised by the Chinese central government should be covered by environmental ethics. The connotation of open environmental ethics includes a respect for nature, care for the individual human race, and respect for the development of future generations, which means giving consideration to natural values, individual and human race benefits and welfare across generations. The role of environmental ethics in regional development consists of cognition, criticism, education, inspiration, adjusting, legislation and promoting environmental regulations. The major problems in regional development are extensive resource exploration, fast population growth, irrational industrial structure, unfair welfare distribution and the twofold effects of science and technology development. The formulation of environmental ethics that aims at regional sustainable development, can not only harmonize the relationship of population, resource, environment and economic development, but also guide behavior selection, push social and political system transformation, strengthen the legal system, and raise environmental awareness of the public.展开更多
Location-aware big data from social media have been widely used to quantitatively characterize natural disasters and disaster-induced losses.It is not clear how human activities collectively respond to a disaster.In t...Location-aware big data from social media have been widely used to quantitatively characterize natural disasters and disaster-induced losses.It is not clear how human activities collectively respond to a disaster.In this study,we examined the collective human activities in response to Typhoon Hato at multi spatial scales using aggregated location request data.We proposed a Multilevel Abrupt Changes Detection(MACD)methodological framework to detect and characterize the abrupt changes in location requests in response to Typhoon Hato.Results show that,at the grid level,most anomaly grids were located within a radius of 53 km around the typhoon trajectory.At the city level,there are significant spatial difference in terms of the human activity recovery duration(230 h on average).At the subnational level,the absolute magnitude of abrupt location request changes is strongly correlated with the typhoon-induced economic losses and the population affected.展开更多
A regulatory framework is proposed to address the expanding role of artificial intelligence(Al)in financial advisory services,prioritizing accountability mechanisms for robo-advisors and defining human responsibility....A regulatory framework is proposed to address the expanding role of artificial intelligence(Al)in financial advisory services,prioritizing accountability mechanisms for robo-advisors and defining human responsibility.Central to the framework is resolving the Al‘black box'challenge-opaque algorithmic processes that risk generating unintended outcomes due to insufficient human oversight or interpretability.Current practices,efficacy,and risks within the fintech robo-advisory sector are systematically evaluated,followed by the design of a governance model to strengthen accountability for Al-driven tools.Hybrid advisory systems combining automation with human supervision are advocated to reduce algorithmic aversion,ensuring personalized,adaptable,and ethically governed financial services.展开更多
During epidemic outbreaks,human behavior is highly influential on the disease transmission and hence affects the course,duration and outcome of the epidemics.In order to examine the feedback effect between the dynamic...During epidemic outbreaks,human behavior is highly influential on the disease transmission and hence affects the course,duration and outcome of the epidemics.In order to examine the feedback effect between the dynamics of the behavioral response and disease outbreak,a simple SIR-βtype model is established by introducing the independent variableβof effective contact rate,characterizing how human behavior interacts with disease transmission dynamics and allowing for the feedback changing over time along the progress of epidemic and population's perception of risk.By a particle swarm optimization algorithm in the solution procedures and time series of COVID-19 data with different shapes of infection peaks,we show that the proposed model,together with such behavioral change mechanism,is capable of capturing the trend of the selected data and can give rise to oscillatory prevalence of different magnitude over time,revealing how different levels of behavioral response affect the waves of infection as well as the evolution of the disease.展开更多
文摘Introduction The Caspian-Black Sea-Mediterranean Corridor["CORRIDOR"]encompasses the Eurasian intercontinental basins of the Caspian,Black,Marmara,Aegean,and Eastern Mediterranean(Levantine)seas with their connecting straits and coasts.Periodic connection/isolation of the basins during the Quaternary predetermined their specific environmental conditions and particular hydrologic regimes,and thus,the area,and especially the Ponto-Caspian,represents a“natural laboratory”to study the responses of semi-isolated and isolated basins to climate changes.
文摘Using cytotoxicity and thymidine uptake assays, we investigated the effects of human recombinant in-terleukin-2 (rIL-2) on the induction of lympholine-activated killer (LAK) activity and cellular proliferation in splenocytes and thymocytes from human fetuses (18-22 weeks). We observed that fetal splenocytes and thymocytes incubated with low doses of rIL-2 (10-100 U ml) developed broad antitumor activity (LAK activity) although the kinetics and magnitudes of the responses were different. It indicated the LAK precursors are present in fetal spleen and thymus. Further, rIL-2 induced a strong proliferative response in splenocytes, but not in thymocytes. On the basis of the findings, we conclude that the responses of fetal splenocytes and thymocytes to IL-2 are different.
文摘The 2030 Agenda for Sustainable Development provides a core framework and platform for global development,mainly characterized by the incorporation of human rights protection responsibilities and explicit acknowledgment of the shared role of development and human rights in safeguarding human dignity and well-being.Human rights responsibilities require states to prioritize human development within their development agenda,achieve human rights through development,and adhere to human rights principles and standards.Integrating human rights responsibilities into the development agenda not only makes development more comprehensive but also provides legal constraints and monitoring mechanisms for the implementation of development goals.The 2030 Agenda for Sustainable Development redefines the relationship between development and human rights and is thus closely aligned with China’s practice of advancing sustainable development and human rights protection simultaneously.Guided by the people-centered development philosophy and new development philosophy,China has accomplished the historic tasks of the fight against poverty and the building of a moderately prosperous society in all respects,while significantly enhancing human rights protection.These achievements have provided a unique country-specific experience of“promoting human rights through development”for the implementation of sustainable development goals.
基金Project(50838009) supported by the National Natural Science Foundation of China
文摘To explore the thermal responses under the non-thermal equilibrium cold environmental conditions,a laboratory study was conducted in climate chamber.The local skin temperatures and thermal sensation of 20 subjects were recorded at 10 min intervals for 90 min under air temperatures of 7.4,9.1,11 and 15 °C.The results show that both local skin temperatures and mean skin temperature decrease not only with the drop of ambient air temperature but also with the exposure time.Local thermal sensation and overall the thermal sensation have the similar temperature-varying and time-varying characteristics.Predicted mean vote(PMV) model cannot correctly predict the thermal sensation under non-thermal equilibrium cold environment.The correlation between local thermal sensation and local skin temperatures shows that thermal sensation is closely related to skin temperature.Skin temperature is an effective indicator of thermal sensation.A linear relationship model between overall thermal sensation and mean skin temperature,considering both ambient temperature and exposure time,was established in the non-thermal equilibrium cold environment,which makes the evaluation of thermal sensation more objective.
基金Research Fund of the Istanbul Technical University under Grant No.MGA-2017-40581the Scientific and Technological Research Council of Turkey-TUBITAK-under Grant No.217M071。
文摘The aim of this study is to create alternative approaches to predict human response to ground vibration.Site measurements were conducted in an urban quarry.The multiple discriminant analysis technique was used to develop classification models.The measured ground vibration values were grouped based on the limit values appearing in the literature.Two classification models were created to predict human response to ground vibration.In addition,classical predictor equations were developed to compare to the classification models.The best equations were chosen considering several error measures.All the models were tested on the independent data.The prediction accuracy of the discriminant analysis models is quite promising.Nearly eighty-nine percent of the test data were correctly classified.The classification models have a combined structure.The results of the models can be directly presented to the neighbors of the studied quarry.The models are not complex.They do not require additional software or information to practice and can be easily used by site engineers.
基金the phased achievement of the CSHRS(China Society for Human Rights Studies)project“Human Rights Obligations of States Regulating the Extraterritorial Human Rights Obligations of Transnational Corporations”(CSHRS2020-25YB)
文摘The extraterritorial application of international human rights conventions is the legal basis for states to regulate the extraterritorial human rights obligations of transnational corporations.In recent years,it has been increasingly challenged by the new trend of the United Nations governing the human rights responsibilities of transnational corporations.A study of existing international rules and practices shows that the extraterritorial application of international human rights conventions depends on the extraterritorial jurisdiction of the States Parties,which mainly includes the actual control over extraterritorial territories and individuals as well as the execution of authority outside the territories.In view of the above,if human rights violations by individuals or transnational corporations occur in areas outside their home territories or are authorized and orchestrated by the home state,the home state shall bear the corresponding human rights responsibilities.Given the restrictive scope of the abovementioned extraterritorial application of international human rights conventions,the international cooperation obligation and the"do no harm"principle may become a new legal basis for states to fulfill their extraterritorial human rights obligations in the future,thereby expanding the basis for the extraterritorial application of international human rights conventions to deal with more serious issues of human rights violations by transnational corporations.However,on the whole,the current identification and codification of states regulating the extraterritorial human rights obligations of transnational corporations should respect the existing rules of international human rights law and should not add any new human rights obligations on states.
文摘This paper deals with mathematical study of diffusive fluid transport and distri- bution in human dermal parts. It accounts the intracellular fluid which continuously flows through the skin shells in order to maintain fluid balance within the body. A mathematical model is envisaged for this process and the finite element method （FEM） is employed to calculate the concentration of the fluid at different skin layers. This estimation is analyzed in relation with other parameters of the tissue medium and the atmosphere.
文摘A primary human renal cell carcinoma was developed as a xenograft (NT-25) and maintained by serial transplantation in nude mice. The effect of UFT on this neogrowth was tested and evaluated as well its distribution in the animal tissues. The concentration of UFT was higher in tumor tissues than that in other tissues and in the animal experimentation UFT was found to be effective on human renal cell carcinoma.
基金a phased result of the Project“China’s Regulation on the Extraterritorial Human Rights Responsibilities of Transnational Corporations”undertaken by China Society for Human Rights Studies(Project No.CSHRS2020-25YB)。
文摘As China’s overseas investment and business operations continue to expand,the issue of human rights risks faced by Chinese transnational corporations abroad has attracted sustained attention from society.In recent years,China has enacted a series of laws,regulations,and policies to better regulate the overseas business conduct of transnational corporations,urging them to respect the human rights of the people in host countries and fulfill their social responsibilities to achieve sustainable development.Meanwhile,China has actively participated in the formulation of the Legally Binding Instrument on Activities of Transnational Corporations and Other Business Enterprises in International Human Rights Law,providing a Chinese solution to promote global governance of transnational corporations.However,in practice,the lack of institutional mechanisms,systems,and industry rules to supervise and guide transnational enterprises in fulfilling their human rights responsibilities,as well as the limited awareness of human rights risks among these enterprises,have resulted in ongoing human rights risks in their overseas business operations,particularly regarding labor rights and environmental rights.In response,China should take its national conditions into consideration and focus on the development trends of human rights issues in the business sector at the international level.Drawing on the experiences of other countries,China should explore and establish institutional and practical measures to regulate the human rights responsibilities of transnational enterprises through legislation,administration,and judiciary actions,in order to address the risks and challenges faced by Chinese enterprises in foreign investments and contribute to the sustainable development of the world and global human rights governance.
基金supported by the project funded by the China Postdoctoral Science Foundation project(2019M661617)the Faculty of Engineering at the University of Nottingham through a PhD studentship awarded to Runqi Liang.
文摘Chromogenic windows enable both energy-saving and daylighting regulation.However,the human response to the luminous environment affected by them is difficult to test,since their features of dynamic change and tinting automatically.This study explores the research methods,including experimental design and statistical analysis,by literature review and an experiment demonstration.The results show that a proper size of the test room is significant to obtain desired data,and the advanced VR technologies have the potential to be applied for testing these dynamic variables.Bayesian approaches are recommended to be tried and get more accurate interference about the experimental results.
基金a phasic research result of the project“Human Rights Obligations of States to Regulate Extraterritorial Acts of Domestic Transnational Corporations(CSHIRS2020-25YB)”of the China Society for Human Rights Studies.
文摘With the adoption of the"Legally Binding Instrument to Regulate,in International Human Rights Law,the Activities of Transnational Corporations and other Business Enterprises"and its revised draft,the codification of the human rights responsibilities of transnational corporations has entered a new era The instrument aims to supplement the shortcomings of transnational corporations in fulfilling their human rights responsibilities by strengthening the obligations of states and to improve the host country’s inadequate remedies for human rights violations by establishing extraterritorial human rights jurisdiction of home countries But the instrument has encountered various challenges because the human rights obligations and legal responsibilities of states go beyond the current domestic human rights systems and impact the existing theories and practices of international human rights law In order to resolve the differences among countries,the future codification of the instrument should be based on existing domestic and international legal systems and practices striking a balance between the interests of developing and developed countries,taking into account the objectives of both the fair treatment of transnational corporations and human rights protection,to promote the regulatory effect of the human rights responsibilities of transnational corporations.
文摘In this study, the immuno-response of recombinant hCG-β and natural hCGβ was comparatively investigated by using Freund's adjuvant. The results showed that, the properties and merits of the antibodies elicited by both kinds of hCG-β were similar. The antisera had high affinity for binding with hCG (Kαγβ≈5.86×108/mol/L, Kαβ≈8.18×108/mol/L), and were found to be effective in inhibiting the binding of 125I-hCG to receptors in rat testes. Results also indicated that, similar to the antisera induced by natural hCG-β, the recombinant hCG-β induced antisera had capacity of neutralizing the biological activities of hCG. Recombinant hCG-β could be used as an immunogen for contraceptive vaccine.
文摘On July 22, 2014, the second group of national human rights education and train- ing bases was announced,increasing the number of national bases from the previous three to a total of eight, which reflects the advancement of human rights education and ~aining in China and has far-reaching significance.
文摘An analysis of nearly 250 years of flood records on the river Eden at Appleby-in-Westmorland has enabled a flood frequency relationship to be established. The most severe floods were in the late 18th and early 19th century. With such a long history of flooding, some remedial measures would have been expected but the local people have, to some extent, adapted to the flood hazard by means of temporary and permanent flood proofing methods such as a cemented board across a doorway and removable flood boards. These measures were overwhelmed during the 2015 flood, as were the flood gates installed by the Environment Agency in 1998. A higher level of protection from floods at Appleby is called for.
基金National Natural Science Foundation of China,No.41071060 No.40701009+2 种基金 No.40830741 National Key Technology R＆D Program,No.2008BAH31B01 Key Project of Knowledge Innovation Program of the Chinese Academy of Sciences,No.KZCX2-YW-322-5
文摘The scientific environmental ethics plays a key role in the recognition of the human-environment interactions. Modern environmental ethics is the philosophical re-thinking of modern human race environmental behavior. The development of environmental ethics theory, as well as its application in reality, determines the viewpoints of environmental ethics. Sustainable development implies harmony on human-environment interactions and inter-generation responsibility, with emphasis on a harmonious relationship among population, resources, environment and development, so as to lay a sustainable and healthy foundation of resources and environment for future generations. The harmonious society construction in China that is raised by the Chinese central government should be covered by environmental ethics. The connotation of open environmental ethics includes a respect for nature, care for the individual human race, and respect for the development of future generations, which means giving consideration to natural values, individual and human race benefits and welfare across generations. The role of environmental ethics in regional development consists of cognition, criticism, education, inspiration, adjusting, legislation and promoting environmental regulations. The major problems in regional development are extensive resource exploration, fast population growth, irrational industrial structure, unfair welfare distribution and the twofold effects of science and technology development. The formulation of environmental ethics that aims at regional sustainable development, can not only harmonize the relationship of population, resource, environment and economic development, but also guide behavior selection, push social and political system transformation, strengthen the legal system, and raise environmental awareness of the public.
基金the National Key R&D Program of China(grant number 2017YFC1503003)the National Key Research and Development Program(grant number 2017YFB0503605)the National Mountain Flood Disaster Investigation Project(SHZH-IWHR-57).
文摘Location-aware big data from social media have been widely used to quantitatively characterize natural disasters and disaster-induced losses.It is not clear how human activities collectively respond to a disaster.In this study,we examined the collective human activities in response to Typhoon Hato at multi spatial scales using aggregated location request data.We proposed a Multilevel Abrupt Changes Detection(MACD)methodological framework to detect and characterize the abrupt changes in location requests in response to Typhoon Hato.Results show that,at the grid level,most anomaly grids were located within a radius of 53 km around the typhoon trajectory.At the city level,there are significant spatial difference in terms of the human activity recovery duration(230 h on average).At the subnational level,the absolute magnitude of abrupt location request changes is strongly correlated with the typhoon-induced economic losses and the population affected.
文摘A regulatory framework is proposed to address the expanding role of artificial intelligence(Al)in financial advisory services,prioritizing accountability mechanisms for robo-advisors and defining human responsibility.Central to the framework is resolving the Al‘black box'challenge-opaque algorithmic processes that risk generating unintended outcomes due to insufficient human oversight or interpretability.Current practices,efficacy,and risks within the fintech robo-advisory sector are systematically evaluated,followed by the design of a governance model to strengthen accountability for Al-driven tools.Hybrid advisory systems combining automation with human supervision are advocated to reduce algorithmic aversion,ensuring personalized,adaptable,and ethically governed financial services.
基金supported by National Natural Science Foundation of China(#62376212)Scientific Research Program Project of Education Department of Shaanxi Province(#23JP114).
文摘During epidemic outbreaks,human behavior is highly influential on the disease transmission and hence affects the course,duration and outcome of the epidemics.In order to examine the feedback effect between the dynamics of the behavioral response and disease outbreak,a simple SIR-βtype model is established by introducing the independent variableβof effective contact rate,characterizing how human behavior interacts with disease transmission dynamics and allowing for the feedback changing over time along the progress of epidemic and population's perception of risk.By a particle swarm optimization algorithm in the solution procedures and time series of COVID-19 data with different shapes of infection peaks,we show that the proposed model,together with such behavioral change mechanism,is capable of capturing the trend of the selected data and can give rise to oscillatory prevalence of different magnitude over time,revealing how different levels of behavioral response affect the waves of infection as well as the evolution of the disease.
