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Reconsideration of the sediment characteristics of the second member of the Triassic Xujiahe Formation in Sanhuiba,Huaying Mountain 被引量:2
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作者 LIAO Taiping HU Jingjing +1 位作者 ZHANG Furong LIU Lijing 《Mining Science and Technology》 EI CAS 2010年第4期591-599,共9页
The second member of the Triassic Xujiahe Formation in the Sanhuiba area in Huaying Mountain is an important section of sedimentary delta facies in the Chongqing Tianfu Geological Survey and Training Base. In spite of... The second member of the Triassic Xujiahe Formation in the Sanhuiba area in Huaying Mountain is an important section of sedimentary delta facies in the Chongqing Tianfu Geological Survey and Training Base. In spite of some initial efforts on its lithology and lithofacies, the existing research is yet to be completed and suffers from contradictory conclusions and inadequate evidence. Starting from the sedimentary microfaeies types and cyclic features, we analyzed the vertical sequence of a sedimentary delta model and discovered that this section is a constructional delta deposit. Eight incomplete and asymmetric regressive cycles are marked off, given that frequent erosion surfaces appeared in the section. Based on the analysis of structural characteristics of every monocycle, we summarized the system of cycles, tracts and sequence characteristics of the overall section. In view of this systematic series of cycles, we discussed the features of the syndepositional tectonic movements in the area and conclude that, due to frequent erosion, migration and diversion of a sub-channel branch was brought about by oscillating movements of the crust. In a comparison with neighboring sections, we explored the cause of erosion and the relations between erosion and cycles. This study greatly strengthens existing research and theories, makes an important and comprehensive contribution to geological surveys and training in the area and provides essential suggestions for coal exploration, oil and gas evaluation and in general to exploration and development in the target stratum. 展开更多
关键词 huaying Mountain Sanhuiba Xujiahe Formation member 2 sandbodies sedimentary characteristics RECONSIDERATION
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Evolution and global correlation for strontium isotopic composition of marine Triassic from Huaying Mountains,eastern Sichuan,China 被引量:5
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作者 ZuoWei Hu SiJing Huang +3 位作者 HaiRuo Qing QingDong Wang ChunMei Wang XiaoYong Gao 《Science China Earth Sciences》 SCIE EI CAS 2008年第4期540-549,共10页
Strontium isotope stratigraphy (SIS) has progressively become an efficient chemostratigraphic tool in the research and correlation of global geological events, such as global sea level fluctuations, orogeny, and paleo... Strontium isotope stratigraphy (SIS) has progressively become an efficient chemostratigraphic tool in the research and correlation of global geological events, such as global sea level fluctuations, orogeny, and paleoclimatic and paleoenvironmental change 展开更多
关键词 TRIASSIC MARINE carbonate STRONTIUM isotope global correlation huaying MOUNTAINS EASTERN SICHUAN
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Paleoecological associations of middle Llandovery (Silurian) corals from Huaying Mountain, eastern Sichuan Province 被引量:3
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作者 WANG GuangXu ZHAN RenBin +1 位作者 DENG ZhanQiu LIU JianBo 《Science China Earth Sciences》 SCIE EI CAS 2013年第4期640-646,共7页
Corals are comparatively abundant in the upper member of the Baiyun'an Formation (upper Aeronian to lowerest Telychian, Llandovery, Silurian) of Huaying, eastern Sichuan Province, Southwest China. Three coral asso... Corals are comparatively abundant in the upper member of the Baiyun'an Formation (upper Aeronian to lowerest Telychian, Llandovery, Silurian) of Huaying, eastern Sichuan Province, Southwest China. Three coral associations have been recognized, i.e., in ascending order, the Mesofavosites Association, the Dentilasma Association, and the Paraceriaster Association. The Mesofavosites Association occurs at horizons indicating a shallow and high-energy environment. It is dominated by large favositids accompanied by a few broken pieces of halysitids and small solitary rugose corals. The Dentilasma Association has a pretty high coral diversity, dominated by the solitary rugose coral Dentilasma meitanense, together with some subordinative heliolitids and favositids. The sedimentary evidence shows that this association might live in a quiet and nutritive shallow water environment. The Paraceriaster Association yields in the grayish green calcareous mudstone indicating a comparatively deep water environment. Systematically it contains abundant fasciculate Paraceriaster micropora and a few favositids. The distinction among these three coral associations shows that corals could adopt different adaptive strategies under different environments, which provide some new data for the investigation on the ecology of Silurian corals and further study on the "Lower Red Beds". 展开更多
关键词 coral associations Baiyun'an Formation Llandovery (Silurian) huaying Mountain eastern Sichuan
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Philosophy of life in Huai Nan-zi:navigating the conscious map to a healthy life from ancient ideas
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作者 Pei-Jin Chen 《History and Philosophy of Medicine》 2026年第1期60-68,共9页
Background:Based on a profound awareness of crisis sense,Huai Nan-zi warns people of the importance of being prepared for danger in times of peace by using the principle that Heaven and Earth are ever-changing and nev... Background:Based on a profound awareness of crisis sense,Huai Nan-zi warns people of the importance of being prepared for danger in times of peace by using the principle that Heaven and Earth are ever-changing and never-ending.It also consciously constructs a cosmic life view of the organic,homologous,isomorphic,and harmonious unity of heaven,earth,and man based on human existence and destiny with a rational thinking attitude.The life philosophy of the Huai Nan-zi offers modern people a completely new holistic view of life and medicine.Not only in China,but also in Western countries,studying its medical philosophical ideas helps us better explore the theoretical roots of TCM in the era of globalized medicine.Methods:This paper mainly uses the analysis method of literature review and chinese philosophy intellectual concepts.It employs the I Ching’s image-number logic thinking method to compare images through analogy and the holistic thinking method of the three-talent view of heaven,earth,and human to understand life consciousness.Results:This article mainly interprets medical philosophy in Huai Nan-zi through three aspects:1)The body of Taoism:heaven,earth,and humanity constitute one unity within the body of the universe;2)The spirit of Taoism:keeping the spirit inward,preserving the essence and suppressing the superficial;and 3)The mind of Taoism:the principle of life governed by the dynamics of gain and loss,prosperity and decline.Conclusion:The philosophy of life presented in the Huai Nan-zi ultimately charts a course toward a state of profound theoretical integration.Its“conscious map”does not lead to a fixed destination,but to a continuous and dynamic mode of being–a life of flourishing known in Chinese as yang sheng,the nurturing of life.The destination,therefore,is the journey itself,undertaken with unwavering cosmic awareness and harmony.This ancient text reminds us that a truly healthy life is not a fragmented pursuit of physical fitness,mental peace,or spiritual insight in isolation.Instead,it is the symphony of all three(Taoist body,spirit,and mind),orchestrated by the fundamental principles of the cosmos.By aligning our inner nature with the outer Tao,we transform our existence from a series of reactive struggles into a graceful and spontaneous free flow.In a modern world characterized by fragmentation,overstimulation,and a relentless push against natural rhythms,the Huai Nan-zi’s life consciousness map is more relevant than ever.The philosophy of Huai Nan-zi not only plays a vital role in the construction of the theoretical system of TCM in ancient East life wisdom,but also is worthwhile for Western life sciences to conduct in-depth exploration and discovery in the age of AI. 展开更多
关键词 Huai Nan-zi embodied spirituality life consciousness theory of qi mind-body monism
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Soil and Water Conservation,Ecological Reconstruction,and Spatial Transformation of Tea Industry in Xinyang City(1952-2000)
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作者 Tengxiao PAN Qing LIU 《Asian Agricultural Research》 2025年第10期14-17,36,共5页
The water conservancy construction and soil and water conservation projects in New China have reshaped the tea industry landscape in Xinyang City of Henan Province from multiple dimensions.In terms of hydraulic techno... The water conservancy construction and soil and water conservation projects in New China have reshaped the tea industry landscape in Xinyang City of Henan Province from multiple dimensions.In terms of hydraulic technology,engineering systems represented by the Nanwan Irrigation District redefined the watershed irrigation pattern,while the application of modern agricultural technologies such as sprinkler and electric irrigation accelerated the shift from traditional experience to scientific management in tea garden practices.Ecologically,systematic soil and water management significantly improved growing conditions,making it possible for tea cultivation to break through the traditional geographical limitation of"tea does not grow north of the Huai River."This integrated governance model not only laid the foundation for the northward expansion of Xinyang's tea industry across the Huai River but also facilitated the transition toward scale and intensification through improved irrigation infrastructure and the breeding of cold-resistant tea varieties.Ultimately,driven by the tripartite interactive mechanism of"engineering governance-ecological improvement-spatial expansion,"the tea industry in Xinyang achieved a historic leap from traditional production to modern intensive development. 展开更多
关键词 Huai RIVER BASIN Xinyang region in HENAN PROVINCE Soil and water control TEA industry
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Well-facilitated farmland improves nitrogen use efficiency and reduces environmental impacts in the Huang-Huai-Hai Region,China
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作者 Xiaoqing Wang Wenjiao Shi +5 位作者 Qiangyi Yu Xiangzheng Deng Lijun Zuo Xiaoli Shi Minglei Wang Jun Li 《Journal of Integrative Agriculture》 2025年第8期3264-3281,共18页
The well-facilitated farmland projects(WFFPs)involve the typical sustainable intensification of farmland use and play a key role in raising food production in China.However,whether such WFFPs can enhance the nitrogen(... The well-facilitated farmland projects(WFFPs)involve the typical sustainable intensification of farmland use and play a key role in raising food production in China.However,whether such WFFPs can enhance the nitrogen(N)use efficiency and reduce environmental impacts is still unclear.Here,we examined the data from 502 valid questionnaires collected from WFFPs in the major grain-producing area,the Huang-Huai-Hai Region(HHHR)in China,with 429 samples for wheat,328 for maize,and 122 for rice.We identified gaps in N use efficiency(NUE)and N losses from the production of the three crops between the sampled WFFPs and counties based on the statistical data.The results showed that compared to the county-level(wheat,39.1%;maize,33.8%;rice,35.1%),the NUEs for wheat(55.2%),maize(52.1%),and rice(50.2%)in the WFFPs were significantly improved(P<0.05).In addition,the intensities of ammonia(NH3)volatilization(9.9-12.2 kg N ha–1),N leaching(6.5-16.9 kg N ha–1),and nitrous oxide(N2O)emissions(1.2-1.6 kg N ha–1)from crop production in the sampled WFFPs were significantly lower than the county averages(P<0.05).Simulations showed that if the N rates are reduced by 10.0,15.0,and 20.0%for the counties,the NUEs of wheat,maize,and rice in the HHHR will increase by 2.9-6.3,2.4-5.2,and 2.6-5.7%,respectively.If the N rate is reduced to the WFFP level in each county,the NUEs of the three crops will increase by 12.9-19.5%,and the N leaching,NH3,and N2O emissions will be reduced by 48.9-56.2,37.4-42.9,and 46.0-66.5%,respectively.Our findings highlight that efficient N management practices in sustainable intensive farmland have considerable potential for reducing environmental impacts. 展开更多
关键词 raising food production environmental impacts sustainable intensification nitrogen use efficiency well facilitated farmland Huang Huai Hai region China sustainable intensification farmland use
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Teochew Spirit Across Borders Teochew Poit Ip Huay Kuan is maintaining cultural roots and cultivating economic fruits for both China and Singapore
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作者 Li Xiaolin 《China Report ASEAN》 2025年第8期41-41,共1页
Founded in 1929 by a group of pioneering Teochew immigrants,Teochew Poit Ip Huay Kuan is now the largest Teochew clan association in Singapore,representing more than 6,000 members.What began as a traditional clan orga... Founded in 1929 by a group of pioneering Teochew immigrants,Teochew Poit Ip Huay Kuan is now the largest Teochew clan association in Singapore,representing more than 6,000 members.What began as a traditional clan organization has transformed into a dynamic international platform that promotes cultural preservation,strengthens business networks,and supports people-to-people diplomacy between Singapore and China.With seven dedicated divisions including cultural education,youth engagement,international affairs,commerce,and public welfare,the association’s mission is to unite Teochew people worldwide,safeguard their heritage,and foster cooperation between Singapore and China.It played a founding role in several major federations including the Malaysian Federation of Teochew Poit It Huay Kuan and the Singapore Federation of Chinese Clan Associations. 展开更多
关键词 SINGAPORE promotes cultural preservationstrengthens business networksand poit ip huay kuan People People Diplomacy Teochew Clan Association teochew clan association Business Networks clan organization
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Simulation and Analysis of Land System Structure Changes in Huang-Huai-Hai Plain Area 被引量:6
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作者 邓祥征 战金艳 +2 位作者 苏红波 姜群鸥 迟百余 《Agricultural Science & Technology》 CAS 2007年第3期45-52,共8页
The dynamic changes of land system in Huang - Huai - Hai Plain between 1988 and 2000 were researched in this paper. Spatial dominance econometric model was estabilished on 1 km cell to quantificafionally analyze the d... The dynamic changes of land system in Huang - Huai - Hai Plain between 1988 and 2000 were researched in this paper. Spatial dominance econometric model was estabilished on 1 km cell to quantificafionally analyze the driving-force for the dynamic change mechanism of land system, such as natural, social and economic factors. The future dynamic changes of land system in Huang - Huai - Hai Plain on each 1 km cell during 2000 to 2020 were stimulated by combining the dynamic changes of land system on each 1 km cell with different situations. The research indicated that the dynamic changes of land system structure changed mainly from the cultivated areas to building areas and industrial areas, and forest areas increased during this period. Although the revolutions of land system structure were different during 2000 to 2020 with the different referrence standard, ecological protection and economic development, the primary dynamic changes of land system structure were that the increase of building land areas with the decline cuhivaled land areas and the increase of woodlands. 展开更多
关键词 LAND Land system Land system structure Land system structure change Land use Dynamic simulation Huang- Huai -Hai Plain
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如何发展社区生态旅游?——泰国Huay Hee村社区生态旅游(CBET)的经验 被引量:30
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作者 何艺玲 《旅游学刊》 CSSCI 北大核心 2002年第6期57-60,共4页
本文介绍了泰国HuayHee村社区生态旅游CBET(Community basedEco tourism)发展的过程和现状 ,认为要成功地发展CBET应该具备以下条件 :初期需要外界支持 ;逐步建立和完善村民的相关旅游组织 ;成立相应的旅游基金会 ,用于资源保护 ;各利... 本文介绍了泰国HuayHee村社区生态旅游CBET(Community basedEco tourism)发展的过程和现状 ,认为要成功地发展CBET应该具备以下条件 :初期需要外界支持 ;逐步建立和完善村民的相关旅游组织 ;成立相应的旅游基金会 ,用于资源保护 ;各利益方要建立良好的合作关系 ,共同制定CBET产品发展计划 ;在CBET计划实施过程中要进行监测和评估。 展开更多
关键词 社区生态旅游 Huay Hee村 PRLC 发展 泰国 旅游活动 旅游产品 CBET
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文学豫军论 被引量:22
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作者 孙荪 《河南大学学报(社会科学版)》 2002年第4期1-6,共6页
文学豫军的形成与发展可分为三个时期 :一、新文学发端到新中国成立 (1 91 5 -1 949)。这一时期 ,河南的文学英才在全国文坛崭露头角 ,但没有形成带有河南地域特色的文学团体和流派。二、新中国建立至 2 0世纪 70年代末。这一时期 ,尽... 文学豫军的形成与发展可分为三个时期 :一、新文学发端到新中国成立 (1 91 5 -1 949)。这一时期 ,河南的文学英才在全国文坛崭露头角 ,但没有形成带有河南地域特色的文学团体和流派。二、新中国建立至 2 0世纪 70年代末。这一时期 ,尽管有李这样有相当影响的作家 ,但河南作家的群体形象尚未树立。三、2 0世纪 80、90年代。这一时期 ,河南文坛老中青几代作家共展辉煌 ,各种文学样式长足进步 ,文学豫军真正形成并健康发展。本文追溯文学发展的历史 ,结合各时期的时代背景 ,重要作家、作品 ,分析、探讨了其特点及形成原因 。 展开更多
关键词 河南 文学研究 小说 李Huai 作家 散文 诗歌 周同宾 文学批评
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Effect of Purple Yam(Dioscorea alata L.) on Nutritional and Physiological Functions of Growing Rats 被引量:1
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作者 宋曙辉 刘庞源 +3 位作者 赵霖 丛涛 李珍 王文琪 《Agricultural Science & Technology》 CAS 2012年第10期2159-2162,2201,共5页
[Objective] This study was to explore the effect of purple yam on the nutritional and physiological functions of rats.[Method] Forty SD rats were randomly divided into four groups with ten rats in each group which wer... [Objective] This study was to explore the effect of purple yam on the nutritional and physiological functions of rats.[Method] Forty SD rats were randomly divided into four groups with ten rats in each group which were reared with artificial semisynthetic feed added with 10% steamed yam powder.The four groups,the casein(CK) group which was used as the control,the purple yam(PY) group,the Tiegun yam(TY) group and common Huai yam(HY) group,were supplied with feed of equal content of energy,protein and fat.The rats were pair-fed for 56 days to observe changes of relevant nutritional and physiological indices.[Result] There were no significant differences of body weight,food conversion rate and organ indices between rats in PY group and CK group.Mean corpuscular hemoglobin in PY group was significantly lower than that in CK group;hemoglobin showed no significant difference with that in CK group;eosnophils was lower than that in CK group.Low density lipoprotein-cholesterol,total cholesterol and atherogenic index in PY group were lower than that in the other three groups;anti-atherogenic index was the highest among the four groups,while showing no significant difference;triglyceride content was lower than that in CK group.Among the antioxidant indices,the activity of catalase and superoxide dismutase were higher than that in CK group,while malondialdehyde content was lower than that in CK group.[Conclusion] Purple yam showed the trend of reducing the content of blood glucose,total cholesterol,low density lipoprotein-cholesterol,triglyceride,malondialdehyde,and raising the activity of glutathione peroxidase,superoxide dismutase and catalase,thus having certain antioxidative function. 展开更多
关键词 Purple yam(Dioscorea alata L.) Huai yam(Dioscorea opposite) Nutritional and physiological functions
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Problems in Landscaping of Residential Areas in Huai'an City and Countermeasures
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作者 罗英 唐亮 朱国春 《Journal of Landscape Research》 2009年第12期15-18,23,共5页
The present landscaping in residential areas of Huai'an City was introduced in this study, problems emerging from the landscaping were analyzed, and corresponding measures were proposed.
关键词 Huai’an CITY Structure of green SPACE Green SPACE in RESIDENTIAL areas
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Tillage and straw mulching impacts on grain yield and water use efficiency of spring maize in Northern Huang–Huai–Hai Valley 被引量:28
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作者 Zhiqiang Tao Congfeng Li +5 位作者 Jingjing Li Zaisong Ding Jie Xu Xuefang Sun Peilu Zhou Ming Zhao 《The Crop Journal》 SCIE CAS CSCD 2015年第5期445-450,共6页
A two-year field experiment(2012–2013) was conducted to investigate the effects of two tillage methods and five maize straw mulching patterns on the yield, water consumption,and water use efficiency(WUE) of spring ma... A two-year field experiment(2012–2013) was conducted to investigate the effects of two tillage methods and five maize straw mulching patterns on the yield, water consumption,and water use efficiency(WUE) of spring maize(Zea mays L.) in the northern Huang–Huai–Hai valley of China. Compared to rotary tillage, subsoil tillage resulted in decreases in water consumption by 6.3–7.8% and increases in maize yield by 644.5–673.9 kg ha-1, soil water content by 2.9–3.0%, and WUE by 12.7–15.2%. Chopped straw mulching led to higher yield,soil water content, and WUE as well as lower water consumption than prostrate whole straw mulching. Mulching with 50% chopped straw had the largest positive effects on maize yield, soil water content, and WUE among the five mulching treatments. Tillage had greater influence on maize yield than straw mulching, whereas straw mulching had greater influence on soil water content, water consumption, and WUE than tillage. These results suggest that 50% chopped straw mulching with subsoil tillage is beneficial in spring maize production aiming at high yield and high WUE in the Huang–Huai–Hai valley. 展开更多
关键词 NORTHERN Huang–Huai–Hai VALLEY Spring maize croppi
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Effectiveness of Huai Qi Huang Granules on Juvenile Collagen-induced Arthritis and Its Influence on Pyroptosis Pathway in Synovial Tissue 被引量:5
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作者 Ting HE Xie XU +6 位作者 Xin-yan ZHANG Pan SHEN Jia-yun LING Yan-xin-li HAN Yu WEN Xiu-fen HU Hui-ling LU 《Current Medical Science》 SCIE CAS 2019年第5期784-793,共10页
Summary:Huai Qi Huang(HQH)exerts great effects in clinic,such as anti-inflammation,immune-regulation,anti-cancer,and so on.However,the mechanism by which HQH protects juvenile idiopathic arthritis(JIA)is obscure.Thus,... Summary:Huai Qi Huang(HQH)exerts great effects in clinic,such as anti-inflammation,immune-regulation,anti-cancer,and so on.However,the mechanism by which HQH protects juvenile idiopathic arthritis(JIA)is obscure.Thus,we explored deeply the protective mechanisms in juvenile collagen-induced arthritis(CIA)rat model.Pyroptosis is Gasdermin D(GSDMD)-dependent programmed cell death,involved in many diseases,such as sepsis.We investigated whether GSDMD-induced pyroptosis take part in mechanisms of juvenile CIA arthritis.Juvenile Wistar rats(3-4 weeks)were injected intradermally with fully emulsified bovine typeⅡcollagen and complete Freund's adjuvant to establish CIA rat models.Later,the CIA rats received oral administration of HQH(4.16 g/kg)once a day from the day 21 of modeling,with the treatment lasting for 28 days.Varieties of indicators were measured for evaluation of anti-inflammation effect of HQH,including hind paw swelling,arthritis scores,micro CT,and histopathological changes and the level of pro-inflammatory cytokines in the serum,including tumor necrosis factor alpha(TNF-α)and interleukin-18(IL-18).The expression of GSDMD and caspasein the joint synovial tissues was detected.The results demonstrated that the expression of the pyroptotic protein GSDMD and its upstream caspase-1 was significantly increased in the synovial tissues of CIA rats.The treatment of HQH ameliorated the symptoms in CIA rats,reduced levels of pro-inflammatory cytokines and hind paw swelling,down-regulated the expression of GDSMD and caspase-1.GSDMDinduced pyroptosis participated in the pathogenesis of CIA rats.The study supported that HQH can effectively improve joints inflammation of juvenile collagen-induced arthritis rats by inhibiting pyroptosis pathway in the joint synovial tissues. 展开更多
关键词 Huai QI HUANG JUVENILE collagen-induced arthritis Gasdermin D PYROPTOSIS
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Sirolimus increases the anti-cancer effect of Huai Er by regulating hypoxia inducible factor-1α-mediated glycolysis in hepatocellular carcinoma 被引量:8
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作者 Lin Zhou Yang Zhao +4 位作者 Li-Chao Pan Jing Wang Xian-Jie Shi Guo-Sheng Du Qiang He 《World Journal of Gastroenterology》 SCIE CAS 2022年第32期4600-4619,共20页
BACKGROUND Glycolysis caused by hypoxia-induced abnormal activation of hypoxia inducible factor-1α(HIF-1α)in the immune microenvironment promotes the progression of hepatocellular carcinoma(HCC),leading to enhanced ... BACKGROUND Glycolysis caused by hypoxia-induced abnormal activation of hypoxia inducible factor-1α(HIF-1α)in the immune microenvironment promotes the progression of hepatocellular carcinoma(HCC),leading to enhanced drug resistance in cancer cells.Therefore,altering the immunosuppressive microenvironment by improving the hypoxic state is a new goal in improving cancer treatment.AIM To analyse the role of HIF-1α,which is closely related to tumour proliferation,invasion,metastasis,and angiogenesis,in the proliferation and invasion of liver cancer,and to explore the HIF-1αpathway-mediated anti-cancer mechanism of sirolimus(SRL)combined with Huai Er.METHODS Previous studies on HCC tissues identified the importance of HIF-1α,glucose transporter 1(GLUT1),and lactate dehydrogenase A(LDHA)expression.In this study,HepG2 and Huh7 cell lines were treated,under hypoxic and normoxic conditions,with a combination of SRL and Huai Er.The effects on proliferation,invasion,cell cycle,and apoptosis were analysed.Proteomics and genomics techniques were used to analyze the HIF-1α-related signalling pathway during SRL combined with Huai Er treatment and its inhibition of the proliferation of HCC cells.RESULTS High levels of HIF-1α,LDHA,and GLUT-1 were found in poorly differentiated HCC,with lower patient survival rates.Hypoxia promoted the proliferation of HepG2 and Huh7 cells and weakened the apoptosis and cell cycle blocking effects of the SRL/Huai Er treatment.This was achieved by activation of HIF-1αand glycolysis in HCC,leading to the upregulation of LDHA,GLUT-1,Akt/mammalian target of rapamycin(mTOR),vascular endothelial growth factor(VEGF),and Forkhead box P3 and downregulation of phosphatase and tensin homolog deleted on chromosome ten(PTEN)and p27.The hypoxia-induced activation of HIF-1αshowed the greatest attenuation in the SRL/Huai Er(S50+H8)group compared to the drug treatments alone(P<0.001).The S50+H8 treatment significantly downregulated the expression of mTOR and HIF-1α,and significantly reduced the expression of VEGF mRNA.Meanwhile,the combined blocking of mTOR and HIF-1αenhanced the downregulation of Akt/mTOR,HIF-1α,LDHA,and GLUT-1 mRNA and resulted in the downregulation of PTEN,p27,and VEGF mRNA(P<0.001).CONCLUSION SRL increases the anti-cancer effect of Huai Er,which reduces the promotion of hypoxia-induced HIF-1αon the Warburg effect by inhibition of the PI3K/Akt/mTOR-HIF-1αand HIF-1α-PTEN signalling pathways in HCC. 展开更多
关键词 Hepatocellular carcinoma SIROLIMUS Huai Er Warburg effect Hypoxia inducible factor-1α
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Real-time flood forecasting of Huai River with flood diversion and retarding areas 被引量:6
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作者 Li Zhijia Bao Hongjun +2 位作者 Xue Cangsheng Hu Yuzhong Fang Hong 《Water Science and Engineering》 EI CAS 2008年第2期10-24,共15页
A combination of the rainfall-runoff module of the Xin’anjiang model, the Muskingum routing method, the water stage simulating hydrologic method, the diffusion wave nonlinear water stage method, and the real-time err... A combination of the rainfall-runoff module of the Xin’anjiang model, the Muskingum routing method, the water stage simulating hydrologic method, the diffusion wave nonlinear water stage method, and the real-time error correction method is applied to the real-time flood forecasting and regulation of the Huai River with flood diversion and retarding areas. The Xin’anjiang model is used to forecast the flood discharge hydrograph of the upstream and tributary. The flood routing of the main channel and flood diversion areas is based on the Muskingum method. The water stage of the downstream boundary condition is calculated with the water stage simulating hydrologic method and the water stages of each cross section are calculated from downstream to upstream with the diffusion wave nonlinear water stage method. The input flood discharge hydrograph from the main channel to the flood diversion area is estimated with the fixed split ratio of the main channel discharge. The flood flow inside the flood retarding area is calculated as a reservoir with the water balance method. The faded-memory forgetting factor least square of error series is used as the real-time error correction method for forecasting discharge and water stage. As an example, the combined models were applied to flood forecasting and regulation of the upper reaches of the Huai River above Lutaizi during the 2007 flood season. The forecast achieves a high accuracy and the results show that the combined models provide a scientific way of flood forecasting and regulation for a complex watershed with flood diversion and retarding areas. 展开更多
关键词 flood forecasting and regulation Xin’anjiang model Muskingum method water stage simulating hydrologic method diffusion wave nonlinear water stage method flood diversion and retarding area Huai River
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Analyses on cancer incidence and mortality in Huai’an area,China,from 2009 to 2011 被引量:3
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作者 Guangjin Yuan Qianwen Li +5 位作者 Yunxiang Du Shunlin Shan Zhimin Wang Enchun Pan Yuan He Ting Wang 《The Chinese-German Journal of Clinical Oncology》 CAS 2012年第9期497-503,共7页
Objective: The aim of the study was to investigate the cancer incidence and mortality in Huai'an area, China, from 2009 to 2011. Methods: The data about cancer incidence and mortality were provided by Huai'an Canc... Objective: The aim of the study was to investigate the cancer incidence and mortality in Huai'an area, China, from 2009 to 2011. Methods: The data about cancer incidence and mortality were provided by Huai'an Cancer Registry, China. Incidence and mortality rates, and standardized rates were calculated by age, gender, areas (urban and rural areas of Huai'an) and cancer sites. Results: The crude incidence rate for all cancer sites was 205.60/105 and the standardized incidence rate was 166.22/10. Both the crude and standardized rates were higher in urban area than in rural area for both sexes. The inci- dence rates increased in people aged 40 and over, and the peak ages of incidence were between 70-75 in both males and females. The crude mortality rate for all cancer sites was 153.88/105 and the standardized mortality rate was 122.14/105. Both the crude and standardized rates were similar in urban and rural areas for both men and women. The mortality rates were at low level under the age 50 in both sexes, but increased after the age 50, reaching the peak at the ages of 80-85 in both males and females. The top 10 most common cancer sites in rank were esophagus, stomach, lung, liver, colon-rectum, breast, pancreas, cervix uteri, brain and central nervous system, and leukemia, accounting for 87.56% of all cancers. The top 10 most leading causes of cancer death in order were cancers of esophagus, lung, liver, stomach, colon-rectum, pancreas, brain and central nervous system, leukemia, breast and lymphoma, accounting for 90.53% of all cancer deaths. Conclusion: Cancer is one kind of major diseases threatening people's health in Huai'an area, China. Cancer prevention and control should be enhanced, especially for esophageal cancer. 展开更多
关键词 CANCER INCIDENCE MORTALITY Huai'an area
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Estimating daily actual evapotranspiration of a rice–wheat rotation system in typical farmland in the Huai River Basin using a two-step model and two one-step models 被引量:2
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作者 LI Meng CHU Rong-hao +2 位作者 Abu Reza Md.Towfiqul ISLAM JIANG Yue-lin SHEN Shuang-he 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2021年第1期274-288,共15页
The objective of this study is to evaluate the performance of three models for estimating daily evapotranspiration(ET) by employing flux observation data from three years(2007, 2008 and 2009) during the growing season... The objective of this study is to evaluate the performance of three models for estimating daily evapotranspiration(ET) by employing flux observation data from three years(2007, 2008 and 2009) during the growing seasons of winter wheat and rice crops cultivated in a farmland ecosystem(Shouxian County) located in the Huai River Basin(HRB), China. The first model is a two-step model(PM-Kc);the other two are one-step models(e.g., Rana-Katerji(R-K) and advection-aridity(AA)). The results showed that the energy closure degrees of eddy covariance(EC) data during winter wheat and rice-growing seasons were reasonable in the HRB, with values ranging from 0.84 to 0.91 and R2 of approximately 0.80. Daily ET of winter wheat showed a slow decreasing trend followed by a rapid increase, while that of rice presented a decreasing trend after an increase. After calibrating the crop coefficient(Kc), the PM–Kc model performed better than the model using the Kc recommended by the Food and Agricultural Organization(FAO). The calibrated key parameters of the R-K model and AA model showed better universality. After calibration, the simulation performance of the PM-Kc model was satisfactory. Both the R-K model and AA model underestimated the daily ET of winter wheat and rice. Compared with that of the R-K model, the simulation result of the AA model was better, especially in the simulation of daily ET of rice. Overall, this research highlighted the consistency of the PM-Kc model to estimate the water demand for rice and wheat crops in the HRB and in similar climatic regions in the world. 展开更多
关键词 daily evapotranspiration crop coefficient crop water demand rice–wheat rotation system Huai River Basin
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Study on Relationship Between Polymorphisms in FSHβ,ESR,PRLR Genes of A Novel Huai Pig Line II and Its Litter Size 被引量:2
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作者 LI Qing-gang LIU Lin-qing +1 位作者 XU Jin-gen TAO Li 《Animal Husbandry and Feed Science》 CAS 2009年第6期5-9,共5页
tract By employing PCR-RFLP technique, we detected the polymorphisms in FSHβ, ESR, PRLR genes of a novel Huai pig line II (generation 1 ) and their effects on initial litter size, and analyzed the aggregation effec... tract By employing PCR-RFLP technique, we detected the polymorphisms in FSHβ, ESR, PRLR genes of a novel Huai pig line II (generation 1 ) and their effects on initial litter size, and analyzed the aggregation effect of multi-gene combined genotype on initial litter size. The results showed that the genotype frequencies of ESR and PRLR genes were in Hardy-Weinberg equilibrium other than the genotype frequency of FSHβ gene. Allele A of FSHβ, ESR and PRLR gene had a positive additive effect on reproductive traits. The favorable genotypes of FSHβ and ESR genes was AA- type, while in PRLR gene was AB-type in the 112 pig individuals detected. With regard to FSHβ and ESR genes, AA-type individuals' TNB of were respectively 1.54 (P 〈0.05) and 2.13 (P 〈 0.01 ) higher than the BB-type individuals'; AA-type individuals' AN B of the two genes were respectively 1.55 ( P 〈 0.05) and 1.82 ( P 〈 0.01 ) higher than the BB-type individuals'. Concerning PRLR gene, AB-type individuals' TNB was 0.77 ( P 〉 0.05 ) and 1.59(P〈0.05) higher than that of AA and BB-type individuals respectively, and ANB was 0.65(P〉0.05) and 1.8( P〈0.01 ) higher than AA and BB-type individuals' respectively. Moreover, our results also showed that the AAAABB combination genotype of FSHβ , ESR, PRLR genes bore more than all other combination genotypes, but only 2 individuals were proved to be AAAABB genotype. Consequently, pyramiding FSHβ and ESR genes could to a large extent enhance TNB and NBA of individuals. Therefore, we advise, in next generation that those individuals with AAAA combination genotype of FSHβ and ESR should be selected to increase frequency of allele A, whether PRLR gene is proper for pyramiding with the other genes or not is still to be studied further. 展开更多
关键词 FSHΒ ESR PRLRI Novel Huai pig line II Utter size
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Assessment of dam impacts on river flow regimes and water quality:a case study of the Huai River Basin in P.R.China 被引量:2
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作者 夏军 张永勇 《Journal of Chongqing University》 CAS 2008年第4期261-276,共16页
The Huai River Basin is a unique area in P.R.China with the highest densities of population and water projects.It is also subject to the most serious water pollution.We proposed a distributional SWAT(Soil and Water As... The Huai River Basin is a unique area in P.R.China with the highest densities of population and water projects.It is also subject to the most serious water pollution.We proposed a distributional SWAT(Soil and Water Assessment Tool) model coupled with a water quality-quantity balance model to evaluate dam impacts on river flow regimes and water quality in the middle and upper reaches of the Huai River Basin.We calibrated and validated the SWAT model with data from 29 selected cross-sections in four typical years(1971,1981,1991 and 1999) and used scenario analysis to compensate for the unavailability of historical data regarding uninterrupted river flows before dam and floodgate construction,a problem of prediction for ungauged basins.The results indicate that dam and floodgate operations tended to reduce runoff,decrease peak value and shift peaking time.The contribution of water projects to river water quality deterioration in the concerned river system was between 0 to 40%,while pollutant discharge contributed to 60% to 100% of the water pollution.Pollution control should therefore be the key to the water quality rehabilitation in the Huai River Basin. 展开更多
关键词 DAMS river control river basin projects prediction in ungauged basins flow regime water environment Huai River Basin
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