AIM:To analyze the changes in scientific output relating to Leber congenital amaurosis(LCA)and forecast the study trends in this field.METHODS:All of the publications in the field of LCA from 2002 to 2022 were collect...AIM:To analyze the changes in scientific output relating to Leber congenital amaurosis(LCA)and forecast the study trends in this field.METHODS:All of the publications in the field of LCA from 2002 to 2022 were collected from Web of Science(WOS)database.We analyzed the quantity(number of publications),quality(citation and H-index)and development trends(relative research interest,RRI)of published LCA research over the last two decades.Moreover,VOSviewer software was applied to define the co-occurrence network of keywords in this field.RESULTS:A total of 2158 publications were ultimately examined.We found that the focus on LCA kept rising and peaked in 2015 and 2018,which is consistent with the development trend of gene therapy.The USA has contributed most to this field with 1162 publications,56674 citations and the highest H-index value(116).The keywords analysis was divided into five clusters to show the hotspots in the field of LCA,namely mechanism-related,genotype-related,local phenotype-related,system phenotype-related,and therapy-related.We also identified gene therapy and antiretinal degeneration therapy as a major focus in recent years.CONCLUSION:Our study illustrates historical research process and future development trends in LCA field.This may help to guide the orientation for further clinical diagnosis,treatment and scientific research.展开更多
Zhou Ting,who works in a securities company in Beijing,has a special liking for hotpot When Haidilao,China's leading hotpot restaurant chain,unveiled its first smart hotpot restaurant in the country's capital ...Zhou Ting,who works in a securities company in Beijing,has a special liking for hotpot When Haidilao,China's leading hotpot restaurant chain,unveiled its first smart hotpot restaurant in the country's capital on October 28,2018,she decided to try it with her friends.展开更多
What began as an unexpected twist turned into a memorable celebra-tion for a couple in Taiyuan,Shanxi Province,who ended up holding their wedding at a hotpot restaurant-where diners cook raw ingre-dients in a simmerin...What began as an unexpected twist turned into a memorable celebra-tion for a couple in Taiyuan,Shanxi Province,who ended up holding their wedding at a hotpot restaurant-where diners cook raw ingre-dients in a simmering pot of broth.The bride,surnamed Zhao,told newspa-per Guangming Daily that they had originally booked another restaurant for their wedding.However,just five days before the big day,the restaurant abruptly informed them it was closing down,forcing the couple to scramble for a new venue.展开更多
When the temperature drops below zero in north China,a familiar winter ritual begins:a bubbling hotpot,an electric blanket on the bed,a steaming kettle on the table-and an entire afternoon spent in a warm,inviting bat...When the temperature drops below zero in north China,a familiar winter ritual begins:a bubbling hotpot,an electric blanket on the bed,a steaming kettle on the table-and an entire afternoon spent in a warm,inviting bathhouse.It is the northern way to embrace the season with warmth and ease,and just how Li Xinru,a 25-year-old Beijing resident,spent her last weekend,when the piercing cold wind finally put a pause on the"one mountain each weekend"plan she’d pursued since September.展开更多
Tunas are among the most economically important fish species and play critical roles in food composition and nutrition of humans.As apex predators,they also keep the marine ecosystem healthy and balanced.Both natural ...Tunas are among the most economically important fish species and play critical roles in food composition and nutrition of humans.As apex predators,they also keep the marine ecosystem healthy and balanced.Both natural and human factors influence the status of this important marine resource and their habitats.There is a large cadre of studies on how tunas are of great significance to the exploitation and management of their fisheries,yet there are few summaries of this research.We aimed to quantitatively and qualitatively synthesize the global knowledge structure and emerging trends in tuna research using bibliometric software.References with"Tuna","Katsuwonus",or"Thunnus"as the subject in the Web of Science Core Collection Database from 1995 to 2019 were visually analyzed using CiteSpace.Publication rate and output,active countries,institutions,authors,and co-cited references were performed.Results suggested that the number of international tuna research papers increased significantly between 2000 and 2010,as a considerable number of high-impact articles emerged during this period.Researchers paid more attention to 19 main topics during this period,notably"overfishing","bycatch","climate change","marine pollution",and"fish management",which all posed potential risks and challenges to tuna survival.Future research should emphasize resolving these challenges and building international cooperation for the proper management of tuna populations.展开更多
基金Supported by the National Natural Science Foundation of China (No.82171076,No.82101159)Science and Technology Commission of Shanghai Municipality (No.20Z11900400)+2 种基金Shanghai Hospital Development Center (No.SHDC2020CR2040B,No.SHDC2020CR5014)Shanghai Collaborative Innovation Center for Translational Medicine (No.TM202115PT)Shanghai Sailing Program (No.22YF1435500).
文摘AIM:To analyze the changes in scientific output relating to Leber congenital amaurosis(LCA)and forecast the study trends in this field.METHODS:All of the publications in the field of LCA from 2002 to 2022 were collected from Web of Science(WOS)database.We analyzed the quantity(number of publications),quality(citation and H-index)and development trends(relative research interest,RRI)of published LCA research over the last two decades.Moreover,VOSviewer software was applied to define the co-occurrence network of keywords in this field.RESULTS:A total of 2158 publications were ultimately examined.We found that the focus on LCA kept rising and peaked in 2015 and 2018,which is consistent with the development trend of gene therapy.The USA has contributed most to this field with 1162 publications,56674 citations and the highest H-index value(116).The keywords analysis was divided into five clusters to show the hotspots in the field of LCA,namely mechanism-related,genotype-related,local phenotype-related,system phenotype-related,and therapy-related.We also identified gene therapy and antiretinal degeneration therapy as a major focus in recent years.CONCLUSION:Our study illustrates historical research process and future development trends in LCA field.This may help to guide the orientation for further clinical diagnosis,treatment and scientific research.
文摘Zhou Ting,who works in a securities company in Beijing,has a special liking for hotpot When Haidilao,China's leading hotpot restaurant chain,unveiled its first smart hotpot restaurant in the country's capital on October 28,2018,she decided to try it with her friends.
文摘What began as an unexpected twist turned into a memorable celebra-tion for a couple in Taiyuan,Shanxi Province,who ended up holding their wedding at a hotpot restaurant-where diners cook raw ingre-dients in a simmering pot of broth.The bride,surnamed Zhao,told newspa-per Guangming Daily that they had originally booked another restaurant for their wedding.However,just five days before the big day,the restaurant abruptly informed them it was closing down,forcing the couple to scramble for a new venue.
文摘When the temperature drops below zero in north China,a familiar winter ritual begins:a bubbling hotpot,an electric blanket on the bed,a steaming kettle on the table-and an entire afternoon spent in a warm,inviting bathhouse.It is the northern way to embrace the season with warmth and ease,and just how Li Xinru,a 25-year-old Beijing resident,spent her last weekend,when the piercing cold wind finally put a pause on the"one mountain each weekend"plan she’d pursued since September.
基金supported by National Natural Science Foundation of China(NSFC)(No.41806126)China Postdoctoral Science Foundation(No.2019M653101).
文摘Tunas are among the most economically important fish species and play critical roles in food composition and nutrition of humans.As apex predators,they also keep the marine ecosystem healthy and balanced.Both natural and human factors influence the status of this important marine resource and their habitats.There is a large cadre of studies on how tunas are of great significance to the exploitation and management of their fisheries,yet there are few summaries of this research.We aimed to quantitatively and qualitatively synthesize the global knowledge structure and emerging trends in tuna research using bibliometric software.References with"Tuna","Katsuwonus",or"Thunnus"as the subject in the Web of Science Core Collection Database from 1995 to 2019 were visually analyzed using CiteSpace.Publication rate and output,active countries,institutions,authors,and co-cited references were performed.Results suggested that the number of international tuna research papers increased significantly between 2000 and 2010,as a considerable number of high-impact articles emerged during this period.Researchers paid more attention to 19 main topics during this period,notably"overfishing","bycatch","climate change","marine pollution",and"fish management",which all posed potential risks and challenges to tuna survival.Future research should emphasize resolving these challenges and building international cooperation for the proper management of tuna populations.
