Dear Editor,Dorsal pontine lesions may cause a variety of complex neuro-ophthalmic deficits,including horizontal gaze palsy(HGP),internuclear ophthalmoplegia,one-and-ahalf syndrome,abducens nerve palsy,skew deviation,...Dear Editor,Dorsal pontine lesions may cause a variety of complex neuro-ophthalmic deficits,including horizontal gaze palsy(HGP),internuclear ophthalmoplegia,one-and-ahalf syndrome,abducens nerve palsy,skew deviation,or any combination of these.Here we present a rare case of an adult patient who developed multiple complicated clinical manifestations after surgical removal of a pontine cavernous hemangioma(PCH).Our case highlights a single pontine lesion may involve complicated neural pathways and result in complicated symptoms and signs,in which abducens nerve palsy or skew deviation is easily missed when combined with HGP.展开更多
Significant differences exist between deep and medium-shallow coalbed methane(CBM)reservoirs.The unclear understanding of flowback and production behavior severely constrains the development of deep CBM resources.To a...Significant differences exist between deep and medium-shallow coalbed methane(CBM)reservoirs.The unclear understanding of flowback and production behavior severely constrains the development of deep CBM resources.To address this challenge,guided by the gas-liquid two-phase flow theory in ultra-low permeability reservoirs,and integrating theoretical analysis,numerical simulation,and insights from production practices,this study classifies the flowback and production stages of deep CBM well considering the Daning-Jixian Block,Eastern Ordos Basin as a representative case.We summarize the flowback characteristics for each stage and establish a standard flowback production type curve,aiming to guide field operations.The results indicate that:(a)The production process of deep CBM horizontal wells can be divided into five distinct stages:initial single-phase water dewatering stage,initial gas appearance to peak water production stage,gas breakthrough to peak gas production stage,stable production and decline stage,and low-rate production stage.(b)Based on reservoir energy,two standard type curves for horizontal well flowback production are established:the‘Sufficient Reservoir Energy’type and the‘Insufficient Reservoir Energy’type.The former achieves a higher initial gas rate(up to 12×10^(4)m^(3)/d)but exhibits poorer stability,while the latter achieves a lower stable rate(up to 8×10^(4)m^(3)/d)but demonstrates stronger stability.Numerical simulation confirms these behavioral patterns and reveals the underlying mechanisms related to the effectively drained area where pressure is significantly depleted.The findings from this study have guided the flowback production operations in 53 deep CBM wells with positive results,demonstrating high potential for broad application.展开更多
Re-fracturing horizontal wells is a critical strategy for enhancing recovery from tight oil reservoirs,but its success depends on the evaluation of candidate wells and locations.This process is complicated by producti...Re-fracturing horizontal wells is a critical strategy for enhancing recovery from tight oil reservoirs,but its success depends on the evaluation of candidate wells and locations.This process is complicated by production-induced alterations in reservoir pressure and geomechanical responses.This study introduces a workflow to evaluate re-fracturing potential by integrating coupled fluid flow and geomechanical modeling for the production of initial hydraulic fractures.We developed a numerical model that simulates the poroelastic response of a tight oil reservoir to depletion from an initial set of hydraulic fractures.To quantify the re-fracturing potential along the horizontal wellbore,a novel composite re-fracturing potential index is proposed where fracture shape,stress,and pressure are considered.This index considers four key physical factors:current reservoir pressure,fracture initiation ease,fracture geometry favorability,and fracture propagation efficiency considering tortuosity.Numerical simulations were conducted for scenarios with both uniform and non-uniform initial hydraulic fractures.The results consistently demonstrate that the optimal locations for re-fracturing are the midpoints between existing fractures,where a favorable balance of high reservoir pressure and altered stress conditions exists.The analysis reveals that the overall re-fracturing potential tends to increase with production time,suggesting that a period of depletion can enhance the geomechanical conditions for subsequent stimulation.Furthermore,a sensitivity analysis on the index weighting factors shows that the optimum re-fracturing strategy is highly dependent on the primary field objective,whether it is maximizing resource contact,ensuring geomechanical feasibility,or avoiding operational complexity.The study concludes that heterogeneity in the initial fracture network creates complex and asymmetric potential profiles,which implies the necessity of case-specific and integrated analysis over simplified assumptions.The proposed methodology provides a framework for optimizing re-fracturing designs in tight oil reservoirs.展开更多
Identifying geohazards such as landslides and methane leakage is crucial during gas extraction from natural gas hydrate(NGH)reservoirs,and understanding reservoir settlement behavior is central to this assessment.Hori...Identifying geohazards such as landslides and methane leakage is crucial during gas extraction from natural gas hydrate(NGH)reservoirs,and understanding reservoir settlement behavior is central to this assessment.Horizontal wells can enlarge the pressure relief zone within the formation,improving single-well productivity,and are therefore considered a promising approach for NGH development.This study examines the settlement response of hydrate-bearing sediments during depressurization using horizontal wells.A fully coupled thermal,hydraulic,mechanical,and chemical(THMC)model with representative reservoir properties(Shenhu region in the South China Sea)is presented accordingly.The simulations show that lower production pressures,while increasing gas output,also intensify formation settlement.The maximum difference in settlement between the lowest and highest production pressures reaches 0.016 m,contributing to more pronounced differential subsidence.Optimal well placement,specifically targeting a low-saturation hydrate zone containing free gas and situated adjacent to a high-saturation hydrate layer,markedly improves both gas production rate and cumulative yield,while reducing overall settlement and limiting changes in effective stress.展开更多
With the continuous development of the offshore wind industry,the design concept of composite foundation has been given attention in the past decade.This paper presents an accurate method for investigating the horizon...With the continuous development of the offshore wind industry,the design concept of composite foundation has been given attention in the past decade.This paper presents an accurate method for investigating the horizontal vibration of monopile-friction wheel composite foundations in layered saturated soil.Firstly,the three-dimensional continuum mechanics theory with the range of linear elasticity is introduced to calculate the frictional resistance distributed on the upper soil surface.Then,the resistances of multilayered soils and inviscid seawater to the pile shaft under horizontal harmonic excitation are obtained using Novak's plane strain model,Biot's porous media theory and radiationwave theory.Thirdly,the expressions for the deformation,bending moment and internal force of the Euler-Bernoulli pile are derived using the boundary conditions with definitephysical meaning and transfer matrix method.By comparing with the results of 1g laboratory test and the idealized formula reported by the literature,the rationality and accuracy of the developed dynamical model can be verified.Finally,this paper conducts a series of worked examples to investigate the influencesof the elastic modulus and thickness of three-layer saturated soil and the location of interlayer soil on the horizontal dynamic vibration of composite foundation.The results show that an increase in elastic modulus of the surface soil is an effective way to improve the dynamic stability of the composite foundation in service conditions.The conclusions drawn from the numerical examples can develop some guidelines for the current foundation design of offshore wind turbines.展开更多
The most common aspect of water conveyance tunnel construction is the use of horizontal and sub-horizontal exploration drilling of headings of a tunnel to predict geology and groundwater conditions.The instability of ...The most common aspect of water conveyance tunnel construction is the use of horizontal and sub-horizontal exploration drilling of headings of a tunnel to predict geology and groundwater conditions.The instability of boreholes,extreme loss of circulation,and high-head inflow are also common in fractured strata,which often inhibit completion of probe holes and the reliability of coring,packer testing,and grouting tests.Casing,consequently,is a significant enabling technology to stabilize fractured intervals and has a hydraulic isolation under coupled mechanical and hydrogeological disturbances.The review is a synthesis of research and engineering experience on methods of casing to be used in horizontal drilling of fractured rock masses used in the exploration of water conveyance tunnels.The geological and working environment is initially outlined with a focus on fracture-adaptable instability processes and the special goings on of underground drilling,such as the restricted workspace,cuttings difficult to move,and fast movement of the competent and crushed regions.Types of casing systems are then listed,including both standard threaded steel strings and telescopic programs,and more specialized casing system types,including expandable casing,swellable sealing elements,and external casing packers.Special focus is made on the sealing of annulus in horizontal holes,wherein slurry loss,gravity segregation,and non-uniform borehole geometry usually worsen isolation.Lastly,the article suggests adaptive choice of strategy according to real-time drilling reaction,and research priorities,such as tunnel-specific performance measurements,coupled hydro-mechanical modelling,and field trials of sophisticated sealing material and data-driven choice making.展开更多
The eddies in the southernmost southern Indian Ocean exert major dynamical and biogeochemical influences on the Earth system.Therefore,disentangling the relative contributions of vertical pumping and horizontal transp...The eddies in the southernmost southern Indian Ocean exert major dynamical and biogeochemical influences on the Earth system.Therefore,disentangling the relative contributions of vertical pumping and horizontal transport to water-property anomalies in the eddy cores is of fundamental importance.Here,the authors introduce a temperaturesalinity gradient-ratio approach(the"R-method")that compares vertical and meridional gradients to quantitatively separate the two processes.Application of the R-method to three-dimensional Argo observations reveals that horizontal transport,rather than vertical pumping,predominantly governs the observed temperature and salinity anomalies within eddy cores in the SIO.Independent theoretical estimations based on background meridional gradients,together with composites formed on isopycnal surfaces,further corroborate this conclusion.The results challenge the conventional assumption that vertical pumping invariably controls eddy-core property anomalies and demonstrate the utility of the R-method for diagnosing eddy impacts in climate and biogeochemical studies.展开更多
The current inertial measurement unit(IMU)and odometry fusion navigation algorithms often incorporate non-holonomic constraints(NHC)to obtain three-dimensional velocity in the navigation frame.However,due to the integ...The current inertial measurement unit(IMU)and odometry fusion navigation algorithms often incorporate non-holonomic constraints(NHC)to obtain three-dimensional velocity in the navigation frame.However,due to the integral nature of the dead reckoning algorithm,the attitude errors of the IMU accumulate over time,causing the velocity transformation results to fail to accurately reflect the threedimensional velocity in the navigation frame.Based on the fact that during a vehicle's horizontal and uniform motion,the vertical acceleration is consistent with gravitational acceleration,this paper proposes an IMU/odometry fusion navigation algorithm based on horizontal attitude constraints(HAC).Building on non-holonomic constraints,this algorithm determines the motion state of the vehicle through accelerometer output and zeroes out the pitch and roll angles during horizontal and uniform motion.Verified through two sets of real-world vehicle test data,this algorithm improves horizontal positioning accuracy by approximately 63%and 70%,and vertical positioning accuracy by 98%and 97%,compared with the traditional NHC IMU/odometer fusion algorithm.展开更多
AIM:To evaluate the clinical outcomes of a new minimally invasive technique using horizontal mattress sutures and Hoffman pockets for four-point refixation of dislocated fourhaptic intraocular lenses(IOLs).METHODS:Thi...AIM:To evaluate the clinical outcomes of a new minimally invasive technique using horizontal mattress sutures and Hoffman pockets for four-point refixation of dislocated fourhaptic intraocular lenses(IOLs).METHODS:This retrospective consecutive case series included eyes with dislocated Akreos AO60 IOLs underwent scleral refixation using a horizontal mattress doubleneedle suture technique with intralamellar knot burial via Hoffman pockets.Clinical outcomes assessed included pre-and postoperative best-corrected visual acuity(BCVA),intraocular pressure(IOP),spherical equivalent(SE),suture duration,IOL centration,and perioperative complications.RESULTS:A total of 10 eyes from 10 patients(6 males)were included.The mean age at the time of IOL refixation was 53.10±13.07y(range:28-68y).The mean interval between initial IOL implantation and dislocation was 8.44±3.54y.The mean postoperative follow-up duration was 11.45±10.30mo.Surgical time averaged 15.3±1.77min,with no intraoperative complications.The mean axial length was 27.16±4.35 mm,with high myopia(HM)as the leading comorbidity(4/10 eyes).Postoperative BCVA significantly improved compared to preoperative values(P=0.025).Postoperative SE was significantly improved compared with preoperative(P=0.01).All IOLs remained centered throughout follow-up.CONCLUSION:This minimally invasive four-point scleral fixation technique offers a safe and effective refixation strategy for dislocated four-haptic IOLs.The horizontal mattress suture configuration combined with Hoffman pockets facilitates durable centration,avoids conjunctival dissection,and could be adopted into routine surgical practice.展开更多
Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(...Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(2025)].In relation to seasonal forecasting and climate projection in the East Asian summer monsoon season,proper simulation of the seasonal migration of rain bands by models is a challenging and limiting factor[section 7.1 in Wang et al.(2025)].展开更多
With the rapid advancement of optoelectronic technology,high-performance photodetectors are increasingly in demand in fields such as environmental monitoring,optical communication,and defense systems,where ultraviolet...With the rapid advancement of optoelectronic technology,high-performance photodetectors are increasingly in demand in fields such as environmental monitoring,optical communication,and defense systems,where ultraviolet detection is critical.However,conventional semiconductor materials suffer from limited UV-visible detection capabilities owing to their narrow bandgaps and high dark currents.To address these challenges,wide-bandgap semiconductors have emerged as promising alternatives.Here,we fabricated a horizontally structured n–n heterojunction photodetector by growingβ-Ga_(2)O_(3) on Si–GaN via plasma-enhanced chemical vapor deposition.The device exhibits a self-powered photocurrent of 3.5 nA at zero bias,enabled by the photovoltaic effect of the space charge region.Under 254-nm and 365-nm illumination,it exhibits rectification behavior,achieving a responsivity of 0.475 m A/W(0 V,220??W/cm~2 at 254 nm)and 257.6 mA/W(-5 V),respectively.Notably,the photodetector demonstrates a high photocurrent-to-dark current ratio of 10~5 under-5-V bias,highlighting its potential for self-powered and high-performance UV detection applications.展开更多
The Michelson Interferometer for Global High-resolution Thermospheric Imaging(MIGHTI)onboard the Ionospheric Connection Explorer(ICON)satellite offers the opportunity to investigate the altitude profile of thermospher...The Michelson Interferometer for Global High-resolution Thermospheric Imaging(MIGHTI)onboard the Ionospheric Connection Explorer(ICON)satellite offers the opportunity to investigate the altitude profile of thermospheric winds.In this study,we used the red-line measurements of MIGHTI to compare with the results estimated by Horizontal Wind Model 14(HWM14).The data selected included both the geomagnetic quiet period(December 2019 to August 2022)and the geomagnetic storm on August 26-28,2021.During the geomagnetic quiet period,the estimations of neutral winds from HWM14 showed relatively good agreement with the observations from ICON.According to the ICON observations,near the equator,zonal winds reverse from westward to eastward at around 06:00 local time(LT)at higher altitudes,and the stronger westward winds appear at later LTs at lower altitudes.At around 16:00 LT,eastward winds at 300 km reverse to westward,and vertical gradients of zonal winds similar to those at sunrise hours can be observed.In the middle latitudes,zonal winds reverse about 2-4 h earlier.Meridional winds vary more significantly than zonal winds with seasonal and latitudinal variations.According to the ICON observations,in the northern low latitudes,vertical reversals of meridional winds are found at 08:00-13:00 LT from 300 to 160 km and at around 18:00 LT from 300 to 200 km during the June solstice.Similar reversals of meridional winds are found at 04:00-07:00 LT from 300 to 160 km and at 22:00-02:00 LT from 270 to 200 km during the December solstice.In the southern low latitudes,meridional wind reversals occur at 08:00-11:00 LT from 200 to 160 km and at 21:00-02:00 LT from 300 to 200 km during the June solstice.During the December solstice,reversals of the meridional wind appear at 20:00-01:00 LT below 200 km and at 06:00-11:00 LT from 300 to 160 km.In the northern middle latitudes,the northward winds are dominant at 08:00-14:00 LT at 230 km during the June solstice.Northward winds persist until 16:00 LT at 160 and 300 km.During the December solstice,the northward winds are dominant from 06:00 to 21:00 LT.The vertical variations in neutral winds during the geomagnetic storm on August 26-28 were analyzed in detail.Both meridional and zonal winds during the active geomagnetic period observed by ICON show distinguishable vertical shear structures at different stages of the storm.On the dayside,during the main phase,the peak velocities of westward winds extend from a higher altitude to a lower altitude,whereas during the recovery phase,the peak velocities of the westward winds extend from lower altitudes to higher altitudes.The velocities of the southward winds are stronger at lower altitudes during the storm.These vertical structures of horizontal winds during the storm could not be reproduced by the HWM14 wind estimations,and the overall response to the storm of the horizontal winds in the low and middle latitudes is underestimated by HWM14.The ICON observations provide a good dataset for improving the HWM wind estimations in the middle and upper atmosphere,especially the vertical variations.展开更多
The effectiveness of horizontal well multi-stage and multi-cluster fracturing in the fractured soft coal seam roof for coalbed methane(CBM) extraction has been demonstrated.This study focuses on the geological charact...The effectiveness of horizontal well multi-stage and multi-cluster fracturing in the fractured soft coal seam roof for coalbed methane(CBM) extraction has been demonstrated.This study focuses on the geological characteristics of the No.5 and No.11 coal seams in the Hancheng Block,Ordos Basin,China.A multi-functional,variable-size rock sample mold capable of securing the wellbore was developed to simulate layered formations comprising strata of varying lithology and thicknesses.A novel segmented fracturing simulation method based on an expandable pipe plugging technique is proposed.Large-scale true triaxial experiments were conducted to investigate the effects of horizontal wellbore location,perforation strategy,roof lithology,and vertical stress difference on fracture propagation,hydraulic energy variation,and the stimulated reservoir volume in horizontal wells targeting the soft coal seam roof.The results indicate that bilateral downward perforation with a phase angle of 120° optimizes hydraulic energy conservation,reduces operational costs,enhances fracture formation,and prevents fracturing failure caused by coal powder generation and migration.This perforation mode is thus considered optimal for coal seam roof fracturing.When the roof consists of sandstone,each perforation cluster tends to initiate a single dominant fracture with a regular geometry.In contrast,hydraulic fractures formed in mudstone roofs display diverse morphology.Due to its high strength,the sandstone roof requires significantly higher pressure for crack initiation and propagation,whereas the mudstone roof,with its strong water sensitivity,exhibits lower fracturing pressures.To mitigate inter-cluster interference,cluster spacing in mudstone roofs should be greater than that in sandstone roofs.Horizontal wellbore placement critically influences fracturing effectiveness.For indirect fracturing in sandstone roofs,an optimal position is 25 mm away from the lithological interface.In contrast,the optimal location for indirect fracturing in mudstone roofs is directly at the lithological interface with the coal seam.Higher vertical stress coefficients lead to increased fractu ring pressures and promote vertical,layer-penetrating fractures.A coefficient of 0.5 is identified as optimal for achieving effective indirect fracturing.This study provides valuable insights for the design and optimization of staged fracturing in horizontal wells targeting crushed soft coal seam roofs.展开更多
Predicting the productivity of multistage fractured horizontal wells plays an important role in exploiting unconventional resources.In recent years,machine learning(ML)models have emerged as a new approach for such st...Predicting the productivity of multistage fractured horizontal wells plays an important role in exploiting unconventional resources.In recent years,machine learning(ML)models have emerged as a new approach for such studies.However,the scarcity of sufficient real data for model training often leads to imprecise predictions,even though the models trained with real data better characterize geological and engineering features.To tackle this issue,we propose an ML model that can obtain reliable results even with a small amount of data samples.Our model integrates the synthetic minority oversampling technique(SMOTE)to expand the data volume,the support vector machine(SVM)for model training,and the particle swarm optimization(PSO)algorithm for optimizing hyperparameters.To enhance the model performance,we conduct feature fusion and dimensionality reduction.Additionally,we examine the influences of different sample sizes and ML models for training.The proposed model demonstrates higher prediction accuracy and generalization ability,achieving a predicted R^(2)value of up to 0.9 for the test set,compared to the traditional ML techniques with an R^(2)of 0.13.This model accurately predicts the production of fractured horizontal wells even with limited samples,supplying an efficient tool for optimizing the production of unconventional resources.Importantly,the model holds the potential applicability to address similar challenges in other fields constrained by scarce data samples.展开更多
The horizontal ecological compensation plays an important role in balancing the interests of all parties and coordinating regional development in the basin.However,the mechanism of ecological compensation based on emb...The horizontal ecological compensation plays an important role in balancing the interests of all parties and coordinating regional development in the basin.However,the mechanism of ecological compensation based on embodied carbon emissions is still poorly understood.Here,taking the Yellow River Basin as the research area,we use the multi-regional input-output(MRIO)model to measure the embodied carbon transfers between its seven urban agglomerations in 2012 and 2017 from the viewpoint of value-added trade benefits.Further,for the first time,the green trade benefits and ecological compensation amounts are analyzed.The results indicate that:(1)The transfer of trade-embodied carbon among the urban agglomerations in the basin showed obvious spatial heterogeneity and geographic proximity effects,and trade-embodied carbon outflows(inflows)had a pattern of"highest in the midstream,second in the downstream,and lowest in the upstream".(2)The industry composition of the urban agglomerations in relation to embodied carbon outflows(inflows)was similar,mainly in the service and heavy manufacturing industries.(3)The spatial pattern of green trade benefits in the basin had shifted from"high in the north and low in the surrounding area"to"high in the east-central part and low in the west".(4)The pattern of ecological compensation in the basin had shifted from the upstream surplus,the middle and downstream deficit to the midstream deficit,and the upstream and downstream surplus.Therefore,we recommend improving energy structures in high-demand urban agglomerations by adopting clean energy,focusing on decarbonization and energy efficiency in resource-rich regions.Additionally,promoting low-carbon economies,especially in the service and heavy manufacturing industries,implementing differentiated emission reduction strategies,and optimizing carbon compensation mechanisms considering regional disparities and resource endowments are crucial.It is expected that the study can enrich the scientific basis of horizontal ecological compensation and increase the fairness of regional carbon emission rights allocation.展开更多
Zika virus(ZIKV)is a mosquito-borne virus belonging to the genus Orthoflavivirus,and the family Flaviviridae.It commonly presents with febrile-like symptoms,neurological issues,and pregnancy complications in humans.Cu...Zika virus(ZIKV)is a mosquito-borne virus belonging to the genus Orthoflavivirus,and the family Flaviviridae.It commonly presents with febrile-like symptoms,neurological issues,and pregnancy complications in humans.Currently,there is no commercial vaccine or specific treatment available to prevent ZIKV infection.Therefore,controlling the epidemic's spread relies on preventing mosquitoes from transmitting the virus.Although various studies have explored the transmission of ZIKV between mosquitoes and vertebrate hosts,comprehensive research on potential mosquito-to-mosquito transmission of ZIKV remains limited.In this study,we conducted systematic laboratory investigations to assess the ability of ZIKV to spread among mosquitoes,and to evaluate the impact of ZIKV infection on mosquito development.Our findings revealed that ZIKV can be transmitted between Aedes aegypti mosquitoes both vertically and horizontally,through oviposition and contact between mosquitoes of the same or opposite sex.Additionally,we observed that ZIKV infection resulted in a reduction in the number of mosquito eggs but an increase in their size.The widespread distribution of ZIKV in infected mosquitoes and the altered levels of hormone related genes following viral infection were noted,which may contribute to viral transmission among mosquitoes and affect mosquito development.This research provides systematic experimental evidence of ZIKV transmission among mosquitoes,which is crucial for developing novel strategies to disrupt the spread of orthoflaviviruses and other mosquitoborne pathogens.展开更多
Understanding the mechanical properties of the lithologies is crucial to accurately determine the horizontal stress magnitude.To investigate the correlation between the rock mass properties and maximum horizontal stre...Understanding the mechanical properties of the lithologies is crucial to accurately determine the horizontal stress magnitude.To investigate the correlation between the rock mass properties and maximum horizontal stress,the three-dimensional(3D)stress tensors at 89 measuring points determined using an improved overcoring technique in nine mines in China were adopted,a newly defined characteristic parameter C_(ERP)was proposed as an indicator for evaluating the structural properties of rock masses,and a fuzzy relation matrix was established using the information distribution method.The results indicate that both the vertical stress and horizontal stress exhibit a good linear growth relationship with depth.There is no remarkable correlation between the elastic modulus,Poisson's ratio and depth,and the distribution of data points is scattered and messy.Moreover,there is no obvious relationship between the rock quality designation(RQD)and depth.The maximum horizontal stress σ_(H) is a function of rock properties,showing a certain linear relationship with the C_(ERP)at the same depth.In addition,the overall change trend of σ_(H) determined by the established fuzzy identification method is to increase with the increase of C_(ERP).The fuzzy identification method also demonstrates a relatively detailed local relationship betweenσ_H and C_(ERP),and the predicted curve rises in a fluctuating way,which is in accord well with the measured stress data.展开更多
Time-averaged thermal convection in a rotating horizontal annulus with a higher temperature at its inner boundary is studied.The centrifugal force plays a stabilizing role,while thermal convection is determined by the...Time-averaged thermal convection in a rotating horizontal annulus with a higher temperature at its inner boundary is studied.The centrifugal force plays a stabilizing role,while thermal convection is determined by the“thermovibrational mechanism”.Convective flow is excited due to oscillations of a non-isothermal rotating fluid.Thermal vibrational convectionmanifests in the form of two-dimensional vortices elongated along the axis of rotation,which develop in a threshold manner with an increase in the amplitude of fluid oscillations.The objective of the present study is to clarify the nature of another phenomenon,i.e.,three-dimensional convective vortices observed in the experiments both before the excitation of the convection described above and in the supercritical region.The experimental study of the oscillatory and the time-averaged flow fields by particle image velocimetry is accompanied by the theoretical research of inertial waves.It is found that three-dimensional fluid flows owe their origin to inertial waves.This is confirmed by a high degree of agreement between the experimental and theoretical results.Experiments with cavities of different lengths indicate that the vortices are clearly seen in cavities thatmeet the conditions of resonant excitation of inertial modes.Furthermore,the length of the cavity has no effect on heat transfer,which is explained by the comparatively low intensity of the wave-induced flows.The main contribution to heat transfer is due to vortices elongated along the axis of rotation.The novel results are of significant practical importance in various fields.展开更多
The escalating global dissemination of plasmid-mediated antibiotic resistance poses a formidable threat to global health.Conjugation stands as a pivotal mechanism for horizontal gene transfer among bacterial populatio...The escalating global dissemination of plasmid-mediated antibiotic resistance poses a formidable threat to global health.Conjugation stands as a pivotal mechanism for horizontal gene transfer among bacterial populations,facilitating the spread of antibiotic resistance genes(ARGs).Microelectrolysis has garnered attention as an efficacious strategy for mitigating antibiotic concentrations in wastewater,yet its potential impact on ARG horizontal transfer remain largely unexplored.This comprehensive investigation unveils that microelectrolysis not only influences but significantly accelerates the conjugative transfer of ARG-harboring plasmids.Remarkably,this phenomenon is corroborated at the microbial community scale,underscoring its ecological relevance.Alarmingly,the study highlights the vulnerability of intestinalmicroorganisms to acquire antibiotic resistance under electrolytic stimulation,posing heightened risks to both animal and human health.Delving deeper,the study elucidates the underlyingmechanisms responsible for this enhanced conjugative transfer.It reveals that microelectrolysis augments the abundance of mating-competent cells,triggers the generation of reactive oxygen species,inflicts modest membrane damage,and upregulates the expression of genes critical for conjugation.These findings collectively contribute to a more profound comprehension of the environmental dissemination dynamics and associated public health implications of ARGs in the context of wastewater treatment employing microelectrolytic technologies.展开更多
The China Spallation Neutron Source(CSNS)is the fourth pulsed accelerator-driven neutron source in the world,and it achieved its design target of 100 kW in 2020.The planned China Spallation Neutron Source Phase II(CSN...The China Spallation Neutron Source(CSNS)is the fourth pulsed accelerator-driven neutron source in the world,and it achieved its design target of 100 kW in 2020.The planned China Spallation Neutron Source Phase II(CSNS-II)commenced in 2024.The CSNS-II linac design primarily involves the addition of a radio-frequency ion source and a section of a superconducting linear accelerator composed of two types of superconducting cavities,namely double-spoke and six-cell elliptical cavities,after the drift tube linac(DTL).The development of the double-spoke superconducting cavity began in early 2021,and by January 2023,the welding,post-processing,and vertical tests of two 324 MHz double-spoke cavity prototypes were completed,with vertical test gradients of 11.6 and 15 MV/m,and Q_(0)≥3×10^(10)@E_(acc)≤10 MV/m.The R&D of the cryomodule began in January 2022.In October 2023,the clean assembly of the double-spoke cavity string and cold mass installation of the cryomodule commenced,with the installation of the cryomodule and valve box completing in two months.In January 2024,a horizontal test of the cryomodule was completed,making it the first double-spoke cavity cryomodule in China.The test results showed that the maximum gradients of the two superconducting cavities at a pulse width of 4 ms and repetition frequency of 25 Hz were 12.8 and 15.2 MV/m,respectively.This article provides a detailed introduction to the double-spoke superconducting cavity,tuner,coupler,and cryomodule,elaborates on the clean assembly of the cavity string and cold mass installation of the cryomodule,and provides a detailed analysis of the horizontal test results.展开更多
文摘Dear Editor,Dorsal pontine lesions may cause a variety of complex neuro-ophthalmic deficits,including horizontal gaze palsy(HGP),internuclear ophthalmoplegia,one-and-ahalf syndrome,abducens nerve palsy,skew deviation,or any combination of these.Here we present a rare case of an adult patient who developed multiple complicated clinical manifestations after surgical removal of a pontine cavernous hemangioma(PCH).Our case highlights a single pontine lesion may involve complicated neural pathways and result in complicated symptoms and signs,in which abducens nerve palsy or skew deviation is easily missed when combined with HGP.
基金supported by the National Science and Technology Major Project of China(No.2025ZD1405702)the Scientific Research and Technology Development Project of PetroChina Coalbed Methane Co.,Ltd.(Project No.25MQCTSG010)Applied Science and Technology Project of PetroChina Company Limited(2023ZZ18YJ04).
文摘Significant differences exist between deep and medium-shallow coalbed methane(CBM)reservoirs.The unclear understanding of flowback and production behavior severely constrains the development of deep CBM resources.To address this challenge,guided by the gas-liquid two-phase flow theory in ultra-low permeability reservoirs,and integrating theoretical analysis,numerical simulation,and insights from production practices,this study classifies the flowback and production stages of deep CBM well considering the Daning-Jixian Block,Eastern Ordos Basin as a representative case.We summarize the flowback characteristics for each stage and establish a standard flowback production type curve,aiming to guide field operations.The results indicate that:(a)The production process of deep CBM horizontal wells can be divided into five distinct stages:initial single-phase water dewatering stage,initial gas appearance to peak water production stage,gas breakthrough to peak gas production stage,stable production and decline stage,and low-rate production stage.(b)Based on reservoir energy,two standard type curves for horizontal well flowback production are established:the‘Sufficient Reservoir Energy’type and the‘Insufficient Reservoir Energy’type.The former achieves a higher initial gas rate(up to 12×10^(4)m^(3)/d)but exhibits poorer stability,while the latter achieves a lower stable rate(up to 8×10^(4)m^(3)/d)but demonstrates stronger stability.Numerical simulation confirms these behavioral patterns and reveals the underlying mechanisms related to the effectively drained area where pressure is significantly depleted.The findings from this study have guided the flowback production operations in 53 deep CBM wells with positive results,demonstrating high potential for broad application.
基金funding from the National Natural Science Foundation of China(No.U24B6001)the CNPC Innovation Fund(No.2021DQ02-0502).
文摘Re-fracturing horizontal wells is a critical strategy for enhancing recovery from tight oil reservoirs,but its success depends on the evaluation of candidate wells and locations.This process is complicated by production-induced alterations in reservoir pressure and geomechanical responses.This study introduces a workflow to evaluate re-fracturing potential by integrating coupled fluid flow and geomechanical modeling for the production of initial hydraulic fractures.We developed a numerical model that simulates the poroelastic response of a tight oil reservoir to depletion from an initial set of hydraulic fractures.To quantify the re-fracturing potential along the horizontal wellbore,a novel composite re-fracturing potential index is proposed where fracture shape,stress,and pressure are considered.This index considers four key physical factors:current reservoir pressure,fracture initiation ease,fracture geometry favorability,and fracture propagation efficiency considering tortuosity.Numerical simulations were conducted for scenarios with both uniform and non-uniform initial hydraulic fractures.The results consistently demonstrate that the optimal locations for re-fracturing are the midpoints between existing fractures,where a favorable balance of high reservoir pressure and altered stress conditions exists.The analysis reveals that the overall re-fracturing potential tends to increase with production time,suggesting that a period of depletion can enhance the geomechanical conditions for subsequent stimulation.Furthermore,a sensitivity analysis on the index weighting factors shows that the optimum re-fracturing strategy is highly dependent on the primary field objective,whether it is maximizing resource contact,ensuring geomechanical feasibility,or avoiding operational complexity.The study concludes that heterogeneity in the initial fracture network creates complex and asymmetric potential profiles,which implies the necessity of case-specific and integrated analysis over simplified assumptions.The proposed methodology provides a framework for optimizing re-fracturing designs in tight oil reservoirs.
基金supported by the State Key Research Development Program of China(Grant No.2021YFC2800905-02)the National Natural Science Foundation of China(Grant No.52304208)。
文摘Identifying geohazards such as landslides and methane leakage is crucial during gas extraction from natural gas hydrate(NGH)reservoirs,and understanding reservoir settlement behavior is central to this assessment.Horizontal wells can enlarge the pressure relief zone within the formation,improving single-well productivity,and are therefore considered a promising approach for NGH development.This study examines the settlement response of hydrate-bearing sediments during depressurization using horizontal wells.A fully coupled thermal,hydraulic,mechanical,and chemical(THMC)model with representative reservoir properties(Shenhu region in the South China Sea)is presented accordingly.The simulations show that lower production pressures,while increasing gas output,also intensify formation settlement.The maximum difference in settlement between the lowest and highest production pressures reaches 0.016 m,contributing to more pronounced differential subsidence.Optimal well placement,specifically targeting a low-saturation hydrate zone containing free gas and situated adjacent to a high-saturation hydrate layer,markedly improves both gas production rate and cumulative yield,while reducing overall settlement and limiting changes in effective stress.
基金supported by the National Natural Science Foundation of China(Grant No.52178329),the China Scholarship Council(Grant No.202306130155)the Postgraduate Scientific Research Innovation Project of Hunan Province,China(Grant No.CX20230442).
文摘With the continuous development of the offshore wind industry,the design concept of composite foundation has been given attention in the past decade.This paper presents an accurate method for investigating the horizontal vibration of monopile-friction wheel composite foundations in layered saturated soil.Firstly,the three-dimensional continuum mechanics theory with the range of linear elasticity is introduced to calculate the frictional resistance distributed on the upper soil surface.Then,the resistances of multilayered soils and inviscid seawater to the pile shaft under horizontal harmonic excitation are obtained using Novak's plane strain model,Biot's porous media theory and radiationwave theory.Thirdly,the expressions for the deformation,bending moment and internal force of the Euler-Bernoulli pile are derived using the boundary conditions with definitephysical meaning and transfer matrix method.By comparing with the results of 1g laboratory test and the idealized formula reported by the literature,the rationality and accuracy of the developed dynamical model can be verified.Finally,this paper conducts a series of worked examples to investigate the influencesof the elastic modulus and thickness of three-layer saturated soil and the location of interlayer soil on the horizontal dynamic vibration of composite foundation.The results show that an increase in elastic modulus of the surface soil is an effective way to improve the dynamic stability of the composite foundation in service conditions.The conclusions drawn from the numerical examples can develop some guidelines for the current foundation design of offshore wind turbines.
文摘The most common aspect of water conveyance tunnel construction is the use of horizontal and sub-horizontal exploration drilling of headings of a tunnel to predict geology and groundwater conditions.The instability of boreholes,extreme loss of circulation,and high-head inflow are also common in fractured strata,which often inhibit completion of probe holes and the reliability of coring,packer testing,and grouting tests.Casing,consequently,is a significant enabling technology to stabilize fractured intervals and has a hydraulic isolation under coupled mechanical and hydrogeological disturbances.The review is a synthesis of research and engineering experience on methods of casing to be used in horizontal drilling of fractured rock masses used in the exploration of water conveyance tunnels.The geological and working environment is initially outlined with a focus on fracture-adaptable instability processes and the special goings on of underground drilling,such as the restricted workspace,cuttings difficult to move,and fast movement of the competent and crushed regions.Types of casing systems are then listed,including both standard threaded steel strings and telescopic programs,and more specialized casing system types,including expandable casing,swellable sealing elements,and external casing packers.Special focus is made on the sealing of annulus in horizontal holes,wherein slurry loss,gravity segregation,and non-uniform borehole geometry usually worsen isolation.Lastly,the article suggests adaptive choice of strategy according to real-time drilling reaction,and research priorities,such as tunnel-specific performance measurements,coupled hydro-mechanical modelling,and field trials of sophisticated sealing material and data-driven choice making.
基金supported by the National Natural Science Foundation of China [grant number 42176001]the State Key Laboratory of Tropical Oceanography,South China Sea Institute of Oceanology,Chinese Academy of Sciences [grant number LTO2106]the STU Scientific Research Foundation for Talents [grant number NTF21009]。
文摘The eddies in the southernmost southern Indian Ocean exert major dynamical and biogeochemical influences on the Earth system.Therefore,disentangling the relative contributions of vertical pumping and horizontal transport to water-property anomalies in the eddy cores is of fundamental importance.Here,the authors introduce a temperaturesalinity gradient-ratio approach(the"R-method")that compares vertical and meridional gradients to quantitatively separate the two processes.Application of the R-method to three-dimensional Argo observations reveals that horizontal transport,rather than vertical pumping,predominantly governs the observed temperature and salinity anomalies within eddy cores in the SIO.Independent theoretical estimations based on background meridional gradients,together with composites formed on isopycnal surfaces,further corroborate this conclusion.The results challenge the conventional assumption that vertical pumping invariably controls eddy-core property anomalies and demonstrate the utility of the R-method for diagnosing eddy impacts in climate and biogeochemical studies.
基金from the National Key Research and Development Program project"Adaptive Navigation Software and Hardware Technology(2018YFB0505200)."。
文摘The current inertial measurement unit(IMU)and odometry fusion navigation algorithms often incorporate non-holonomic constraints(NHC)to obtain three-dimensional velocity in the navigation frame.However,due to the integral nature of the dead reckoning algorithm,the attitude errors of the IMU accumulate over time,causing the velocity transformation results to fail to accurately reflect the threedimensional velocity in the navigation frame.Based on the fact that during a vehicle's horizontal and uniform motion,the vertical acceleration is consistent with gravitational acceleration,this paper proposes an IMU/odometry fusion navigation algorithm based on horizontal attitude constraints(HAC).Building on non-holonomic constraints,this algorithm determines the motion state of the vehicle through accelerometer output and zeroes out the pitch and roll angles during horizontal and uniform motion.Verified through two sets of real-world vehicle test data,this algorithm improves horizontal positioning accuracy by approximately 63%and 70%,and vertical positioning accuracy by 98%and 97%,compared with the traditional NHC IMU/odometer fusion algorithm.
文摘AIM:To evaluate the clinical outcomes of a new minimally invasive technique using horizontal mattress sutures and Hoffman pockets for four-point refixation of dislocated fourhaptic intraocular lenses(IOLs).METHODS:This retrospective consecutive case series included eyes with dislocated Akreos AO60 IOLs underwent scleral refixation using a horizontal mattress doubleneedle suture technique with intralamellar knot burial via Hoffman pockets.Clinical outcomes assessed included pre-and postoperative best-corrected visual acuity(BCVA),intraocular pressure(IOP),spherical equivalent(SE),suture duration,IOL centration,and perioperative complications.RESULTS:A total of 10 eyes from 10 patients(6 males)were included.The mean age at the time of IOL refixation was 53.10±13.07y(range:28-68y).The mean interval between initial IOL implantation and dislocation was 8.44±3.54y.The mean postoperative follow-up duration was 11.45±10.30mo.Surgical time averaged 15.3±1.77min,with no intraoperative complications.The mean axial length was 27.16±4.35 mm,with high myopia(HM)as the leading comorbidity(4/10 eyes).Postoperative BCVA significantly improved compared to preoperative values(P=0.025).Postoperative SE was significantly improved compared with preoperative(P=0.01).All IOLs remained centered throughout follow-up.CONCLUSION:This minimally invasive four-point scleral fixation technique offers a safe and effective refixation strategy for dislocated four-haptic IOLs.The horizontal mattress suture configuration combined with Hoffman pockets facilitates durable centration,avoids conjunctival dissection,and could be adopted into routine surgical practice.
文摘Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(2025)].In relation to seasonal forecasting and climate projection in the East Asian summer monsoon season,proper simulation of the seasonal migration of rain bands by models is a challenging and limiting factor[section 7.1 in Wang et al.(2025)].
基金Project supported by the Joints Fund of the National Natural Science Foundation of China(Grant No.U23A20349)the Young Scientists Fund of the National Natural Science Foundation of China(Grant Nos.62204126,62305171,62304113)。
文摘With the rapid advancement of optoelectronic technology,high-performance photodetectors are increasingly in demand in fields such as environmental monitoring,optical communication,and defense systems,where ultraviolet detection is critical.However,conventional semiconductor materials suffer from limited UV-visible detection capabilities owing to their narrow bandgaps and high dark currents.To address these challenges,wide-bandgap semiconductors have emerged as promising alternatives.Here,we fabricated a horizontally structured n–n heterojunction photodetector by growingβ-Ga_(2)O_(3) on Si–GaN via plasma-enhanced chemical vapor deposition.The device exhibits a self-powered photocurrent of 3.5 nA at zero bias,enabled by the photovoltaic effect of the space charge region.Under 254-nm and 365-nm illumination,it exhibits rectification behavior,achieving a responsivity of 0.475 m A/W(0 V,220??W/cm~2 at 254 nm)and 257.6 mA/W(-5 V),respectively.Notably,the photodetector demonstrates a high photocurrent-to-dark current ratio of 10~5 under-5-V bias,highlighting its potential for self-powered and high-performance UV detection applications.
基金supported by the National Key R&D Program of China (Grant No.2022YFF0503700)the special funds of Hubei Luojia Laboratory (Grant No.220100011)+1 种基金supported by the International Space Science Institute–Beijing(ISSI-BJ) project“The Electromagnetic Data Validation and Scientific Application Research based on CSES Satellite”and ISSI/ISSI-BJ project,“Multi-Scale Magnetosphere–Ionosphere–Thermosphere Interaction.”
文摘The Michelson Interferometer for Global High-resolution Thermospheric Imaging(MIGHTI)onboard the Ionospheric Connection Explorer(ICON)satellite offers the opportunity to investigate the altitude profile of thermospheric winds.In this study,we used the red-line measurements of MIGHTI to compare with the results estimated by Horizontal Wind Model 14(HWM14).The data selected included both the geomagnetic quiet period(December 2019 to August 2022)and the geomagnetic storm on August 26-28,2021.During the geomagnetic quiet period,the estimations of neutral winds from HWM14 showed relatively good agreement with the observations from ICON.According to the ICON observations,near the equator,zonal winds reverse from westward to eastward at around 06:00 local time(LT)at higher altitudes,and the stronger westward winds appear at later LTs at lower altitudes.At around 16:00 LT,eastward winds at 300 km reverse to westward,and vertical gradients of zonal winds similar to those at sunrise hours can be observed.In the middle latitudes,zonal winds reverse about 2-4 h earlier.Meridional winds vary more significantly than zonal winds with seasonal and latitudinal variations.According to the ICON observations,in the northern low latitudes,vertical reversals of meridional winds are found at 08:00-13:00 LT from 300 to 160 km and at around 18:00 LT from 300 to 200 km during the June solstice.Similar reversals of meridional winds are found at 04:00-07:00 LT from 300 to 160 km and at 22:00-02:00 LT from 270 to 200 km during the December solstice.In the southern low latitudes,meridional wind reversals occur at 08:00-11:00 LT from 200 to 160 km and at 21:00-02:00 LT from 300 to 200 km during the June solstice.During the December solstice,reversals of the meridional wind appear at 20:00-01:00 LT below 200 km and at 06:00-11:00 LT from 300 to 160 km.In the northern middle latitudes,the northward winds are dominant at 08:00-14:00 LT at 230 km during the June solstice.Northward winds persist until 16:00 LT at 160 and 300 km.During the December solstice,the northward winds are dominant from 06:00 to 21:00 LT.The vertical variations in neutral winds during the geomagnetic storm on August 26-28 were analyzed in detail.Both meridional and zonal winds during the active geomagnetic period observed by ICON show distinguishable vertical shear structures at different stages of the storm.On the dayside,during the main phase,the peak velocities of westward winds extend from a higher altitude to a lower altitude,whereas during the recovery phase,the peak velocities of the westward winds extend from lower altitudes to higher altitudes.The velocities of the southward winds are stronger at lower altitudes during the storm.These vertical structures of horizontal winds during the storm could not be reproduced by the HWM14 wind estimations,and the overall response to the storm of the horizontal winds in the low and middle latitudes is underestimated by HWM14.The ICON observations provide a good dataset for improving the HWM wind estimations in the middle and upper atmosphere,especially the vertical variations.
基金support from China National Natural Science Foundation (11672333)。
文摘The effectiveness of horizontal well multi-stage and multi-cluster fracturing in the fractured soft coal seam roof for coalbed methane(CBM) extraction has been demonstrated.This study focuses on the geological characteristics of the No.5 and No.11 coal seams in the Hancheng Block,Ordos Basin,China.A multi-functional,variable-size rock sample mold capable of securing the wellbore was developed to simulate layered formations comprising strata of varying lithology and thicknesses.A novel segmented fracturing simulation method based on an expandable pipe plugging technique is proposed.Large-scale true triaxial experiments were conducted to investigate the effects of horizontal wellbore location,perforation strategy,roof lithology,and vertical stress difference on fracture propagation,hydraulic energy variation,and the stimulated reservoir volume in horizontal wells targeting the soft coal seam roof.The results indicate that bilateral downward perforation with a phase angle of 120° optimizes hydraulic energy conservation,reduces operational costs,enhances fracture formation,and prevents fracturing failure caused by coal powder generation and migration.This perforation mode is thus considered optimal for coal seam roof fracturing.When the roof consists of sandstone,each perforation cluster tends to initiate a single dominant fracture with a regular geometry.In contrast,hydraulic fractures formed in mudstone roofs display diverse morphology.Due to its high strength,the sandstone roof requires significantly higher pressure for crack initiation and propagation,whereas the mudstone roof,with its strong water sensitivity,exhibits lower fracturing pressures.To mitigate inter-cluster interference,cluster spacing in mudstone roofs should be greater than that in sandstone roofs.Horizontal wellbore placement critically influences fracturing effectiveness.For indirect fracturing in sandstone roofs,an optimal position is 25 mm away from the lithological interface.In contrast,the optimal location for indirect fracturing in mudstone roofs is directly at the lithological interface with the coal seam.Higher vertical stress coefficients lead to increased fractu ring pressures and promote vertical,layer-penetrating fractures.A coefficient of 0.5 is identified as optimal for achieving effective indirect fracturing.This study provides valuable insights for the design and optimization of staged fracturing in horizontal wells targeting crushed soft coal seam roofs.
基金supported by the National Natural Science Foundation of China(52274055)the Shandong Provincial Natural Science Foundation(ZR2022YQ50)the Taishan Scholar Program of Shandong Province(tsqn202408088)。
文摘Predicting the productivity of multistage fractured horizontal wells plays an important role in exploiting unconventional resources.In recent years,machine learning(ML)models have emerged as a new approach for such studies.However,the scarcity of sufficient real data for model training often leads to imprecise predictions,even though the models trained with real data better characterize geological and engineering features.To tackle this issue,we propose an ML model that can obtain reliable results even with a small amount of data samples.Our model integrates the synthetic minority oversampling technique(SMOTE)to expand the data volume,the support vector machine(SVM)for model training,and the particle swarm optimization(PSO)algorithm for optimizing hyperparameters.To enhance the model performance,we conduct feature fusion and dimensionality reduction.Additionally,we examine the influences of different sample sizes and ML models for training.The proposed model demonstrates higher prediction accuracy and generalization ability,achieving a predicted R^(2)value of up to 0.9 for the test set,compared to the traditional ML techniques with an R^(2)of 0.13.This model accurately predicts the production of fractured horizontal wells even with limited samples,supplying an efficient tool for optimizing the production of unconventional resources.Importantly,the model holds the potential applicability to address similar challenges in other fields constrained by scarce data samples.
基金supported by the National Natural Science Foundation of China(Grant number 42201302)the"Double First-Class"University Construction Project of Lanzhou University(Grant number:561120213)。
文摘The horizontal ecological compensation plays an important role in balancing the interests of all parties and coordinating regional development in the basin.However,the mechanism of ecological compensation based on embodied carbon emissions is still poorly understood.Here,taking the Yellow River Basin as the research area,we use the multi-regional input-output(MRIO)model to measure the embodied carbon transfers between its seven urban agglomerations in 2012 and 2017 from the viewpoint of value-added trade benefits.Further,for the first time,the green trade benefits and ecological compensation amounts are analyzed.The results indicate that:(1)The transfer of trade-embodied carbon among the urban agglomerations in the basin showed obvious spatial heterogeneity and geographic proximity effects,and trade-embodied carbon outflows(inflows)had a pattern of"highest in the midstream,second in the downstream,and lowest in the upstream".(2)The industry composition of the urban agglomerations in relation to embodied carbon outflows(inflows)was similar,mainly in the service and heavy manufacturing industries.(3)The spatial pattern of green trade benefits in the basin had shifted from"high in the north and low in the surrounding area"to"high in the east-central part and low in the west".(4)The pattern of ecological compensation in the basin had shifted from the upstream surplus,the middle and downstream deficit to the midstream deficit,and the upstream and downstream surplus.Therefore,we recommend improving energy structures in high-demand urban agglomerations by adopting clean energy,focusing on decarbonization and energy efficiency in resource-rich regions.Additionally,promoting low-carbon economies,especially in the service and heavy manufacturing industries,implementing differentiated emission reduction strategies,and optimizing carbon compensation mechanisms considering regional disparities and resource endowments are crucial.It is expected that the study can enrich the scientific basis of horizontal ecological compensation and increase the fairness of regional carbon emission rights allocation.
基金supported by National Key Research and Development Program of China,China(2024YFD1800102,2022YFD1800105 and 2022YFD1801500)National Natural Science Foundation of China,China(32372993 and 32030107)Fundamental Research Funds for the Central Universities,China(2662023PY005).
文摘Zika virus(ZIKV)is a mosquito-borne virus belonging to the genus Orthoflavivirus,and the family Flaviviridae.It commonly presents with febrile-like symptoms,neurological issues,and pregnancy complications in humans.Currently,there is no commercial vaccine or specific treatment available to prevent ZIKV infection.Therefore,controlling the epidemic's spread relies on preventing mosquitoes from transmitting the virus.Although various studies have explored the transmission of ZIKV between mosquitoes and vertebrate hosts,comprehensive research on potential mosquito-to-mosquito transmission of ZIKV remains limited.In this study,we conducted systematic laboratory investigations to assess the ability of ZIKV to spread among mosquitoes,and to evaluate the impact of ZIKV infection on mosquito development.Our findings revealed that ZIKV can be transmitted between Aedes aegypti mosquitoes both vertically and horizontally,through oviposition and contact between mosquitoes of the same or opposite sex.Additionally,we observed that ZIKV infection resulted in a reduction in the number of mosquito eggs but an increase in their size.The widespread distribution of ZIKV in infected mosquitoes and the altered levels of hormone related genes following viral infection were noted,which may contribute to viral transmission among mosquitoes and affect mosquito development.This research provides systematic experimental evidence of ZIKV transmission among mosquitoes,which is crucial for developing novel strategies to disrupt the spread of orthoflaviviruses and other mosquitoborne pathogens.
基金financially supported by the National Natural Science Foundation of China(No.52204084)the Open Research Fund of the State Key Laboratory of Coal Resources and safe Mining,CUMT,China(No.SKLCRSM 23KF004)+3 种基金the Interdisciplinary Research Project for Young Teachers of USTB(Fundamental Research Funds for the Central Universities),China(No.FRF-IDRY-GD22-002)the Fundamental Research Funds for the Central Universities and the Youth Teacher International Exchange and Growth Program,China(No.QNXM20220009)the National Key R&D Program of China(Nos.2022YFC2905600 and 2022 YFC3004601)the Science,Technology&Innovation Project of Xiongan New Area,China(No.2023XAGG0061)。
文摘Understanding the mechanical properties of the lithologies is crucial to accurately determine the horizontal stress magnitude.To investigate the correlation between the rock mass properties and maximum horizontal stress,the three-dimensional(3D)stress tensors at 89 measuring points determined using an improved overcoring technique in nine mines in China were adopted,a newly defined characteristic parameter C_(ERP)was proposed as an indicator for evaluating the structural properties of rock masses,and a fuzzy relation matrix was established using the information distribution method.The results indicate that both the vertical stress and horizontal stress exhibit a good linear growth relationship with depth.There is no remarkable correlation between the elastic modulus,Poisson's ratio and depth,and the distribution of data points is scattered and messy.Moreover,there is no obvious relationship between the rock quality designation(RQD)and depth.The maximum horizontal stress σ_(H) is a function of rock properties,showing a certain linear relationship with the C_(ERP)at the same depth.In addition,the overall change trend of σ_(H) determined by the established fuzzy identification method is to increase with the increase of C_(ERP).The fuzzy identification method also demonstrates a relatively detailed local relationship betweenσ_H and C_(ERP),and the predicted curve rises in a fluctuating way,which is in accord well with the measured stress data.
基金funded by the Ministry of Education of the Russian Federation within the framework of a state assignment,number 1023032300071-6-2.3.1.
文摘Time-averaged thermal convection in a rotating horizontal annulus with a higher temperature at its inner boundary is studied.The centrifugal force plays a stabilizing role,while thermal convection is determined by the“thermovibrational mechanism”.Convective flow is excited due to oscillations of a non-isothermal rotating fluid.Thermal vibrational convectionmanifests in the form of two-dimensional vortices elongated along the axis of rotation,which develop in a threshold manner with an increase in the amplitude of fluid oscillations.The objective of the present study is to clarify the nature of another phenomenon,i.e.,three-dimensional convective vortices observed in the experiments both before the excitation of the convection described above and in the supercritical region.The experimental study of the oscillatory and the time-averaged flow fields by particle image velocimetry is accompanied by the theoretical research of inertial waves.It is found that three-dimensional fluid flows owe their origin to inertial waves.This is confirmed by a high degree of agreement between the experimental and theoretical results.Experiments with cavities of different lengths indicate that the vortices are clearly seen in cavities thatmeet the conditions of resonant excitation of inertial modes.Furthermore,the length of the cavity has no effect on heat transfer,which is explained by the comparatively low intensity of the wave-induced flows.The main contribution to heat transfer is due to vortices elongated along the axis of rotation.The novel results are of significant practical importance in various fields.
基金supported by Jiangsu Agriculture Science and Technology Innovation Fund(No.CX(22)3001)。
文摘The escalating global dissemination of plasmid-mediated antibiotic resistance poses a formidable threat to global health.Conjugation stands as a pivotal mechanism for horizontal gene transfer among bacterial populations,facilitating the spread of antibiotic resistance genes(ARGs).Microelectrolysis has garnered attention as an efficacious strategy for mitigating antibiotic concentrations in wastewater,yet its potential impact on ARG horizontal transfer remain largely unexplored.This comprehensive investigation unveils that microelectrolysis not only influences but significantly accelerates the conjugative transfer of ARG-harboring plasmids.Remarkably,this phenomenon is corroborated at the microbial community scale,underscoring its ecological relevance.Alarmingly,the study highlights the vulnerability of intestinalmicroorganisms to acquire antibiotic resistance under electrolytic stimulation,posing heightened risks to both animal and human health.Delving deeper,the study elucidates the underlyingmechanisms responsible for this enhanced conjugative transfer.It reveals that microelectrolysis augments the abundance of mating-competent cells,triggers the generation of reactive oxygen species,inflicts modest membrane damage,and upregulates the expression of genes critical for conjugation.These findings collectively contribute to a more profound comprehension of the environmental dissemination dynamics and associated public health implications of ARGs in the context of wastewater treatment employing microelectrolytic technologies.
文摘The China Spallation Neutron Source(CSNS)is the fourth pulsed accelerator-driven neutron source in the world,and it achieved its design target of 100 kW in 2020.The planned China Spallation Neutron Source Phase II(CSNS-II)commenced in 2024.The CSNS-II linac design primarily involves the addition of a radio-frequency ion source and a section of a superconducting linear accelerator composed of two types of superconducting cavities,namely double-spoke and six-cell elliptical cavities,after the drift tube linac(DTL).The development of the double-spoke superconducting cavity began in early 2021,and by January 2023,the welding,post-processing,and vertical tests of two 324 MHz double-spoke cavity prototypes were completed,with vertical test gradients of 11.6 and 15 MV/m,and Q_(0)≥3×10^(10)@E_(acc)≤10 MV/m.The R&D of the cryomodule began in January 2022.In October 2023,the clean assembly of the double-spoke cavity string and cold mass installation of the cryomodule commenced,with the installation of the cryomodule and valve box completing in two months.In January 2024,a horizontal test of the cryomodule was completed,making it the first double-spoke cavity cryomodule in China.The test results showed that the maximum gradients of the two superconducting cavities at a pulse width of 4 ms and repetition frequency of 25 Hz were 12.8 and 15.2 MV/m,respectively.This article provides a detailed introduction to the double-spoke superconducting cavity,tuner,coupler,and cryomodule,elaborates on the clean assembly of the cavity string and cold mass installation of the cryomodule,and provides a detailed analysis of the horizontal test results.
