The addition of high-content crumb rubber(HCCR)in asphalt can effectively address waste tire pollution and provide sustainable environmental and economic advantages.However,the practical application of conventional ru...The addition of high-content crumb rubber(HCCR)in asphalt can effectively address waste tire pollution and provide sustainable environmental and economic advantages.However,the practical application of conventional rubberized binders is significantly limited by high viscosity and poor storage stability.To address these issues,researchers have pretreated crumb rubber(CR)with oil,but high-temperature performance remains insufficient.Therefore,this study aimed to optimize the viscosity,storage stability,and rheological properties of high-content crumb rubber-modified asphalt(HCCRMA)by varying the pretreatment levels of CR and incorporating various additives,including styrene-butadiene-styrene(SBS),deoiled asphalt(DA),or recycled low-density polyethylene(RLDPE).In addition,CR was pretreated with waste cooking oil(WCO)at various ratios,pre-swelling temperatures,and times.The results show that DA exhibits excellent storage stability and lower viscosity compared with other modifiers in HCCRMA,and the 4%RLDPE with pretreated HCCR has the greatest high-temperature rutting resistance.The inclusion of RLDPE increases the stiffness and elasticity of the modified asphalt,which results in greater high-temperature performance.Additionally,the fluorescence microscopy(FM)test confirms that SBS exhibits better dispersion than other modifiers and forms a more homogeneous phase separation in the HCCRMA.All in all,this research achieved an optimal balance of storage stability and rheological properties in asphalt modified with pretreated HCCR and 6%SBS,which provides a valuable reference for performance improvement of HCCR-modified binders.展开更多
The rapid advent in artificial intelligence and big data has revolutionized the dynamic requirement in the demands of the computing resource for executing specific tasks in the cloud environment.The process of achievi...The rapid advent in artificial intelligence and big data has revolutionized the dynamic requirement in the demands of the computing resource for executing specific tasks in the cloud environment.The process of achieving autonomic resource management is identified to be a herculean task due to its huge distributed and heterogeneous environment.Moreover,the cloud network needs to provide autonomic resource management and deliver potential services to the clients by complying with the requirements of Quality-of-Service(QoS)without impacting the Service Level Agreements(SLAs).However,the existing autonomic cloud resource managing frameworks are not capable in handling the resources of the cloud with its dynamic requirements.In this paper,Coot Bird Behavior Model-based Workload Aware Autonomic Resource Management Scheme(CBBM-WARMS)is proposed for handling the dynamic requirements of cloud resources through the estimation of workload that need to be policed by the cloud environment.This CBBM-WARMS initially adopted the algorithm of adaptive density peak clustering for workloads clustering of the cloud.Then,it utilized the fuzzy logic during the process of workload scheduling for achieving the determining the availability of cloud resources.It further used CBBM for potential Virtual Machine(VM)deployment that attributes towards the provision of optimal resources.It is proposed with the capability of achieving optimal QoS with minimized time,energy consumption,SLA cost and SLA violation.The experimental validation of the proposed CBBMWARMS confirms minimized SLA cost of 19.21%and reduced SLA violation rate of 18.74%,better than the compared autonomic cloud resource managing frameworks.展开更多
An augmented flight dynamics model is developed to extend the existing flight dynamics model of tilt-rotor aircraft for optimal landing procedure analysis in the event of one engine failure.Compared with the existing ...An augmented flight dynamics model is developed to extend the existing flight dynamics model of tilt-rotor aircraft for optimal landing procedure analysis in the event of one engine failure.Compared with the existing flight dynamics model, the augmented model involves with more pilot control information in cockpit and is validated against the flight test data. Based on the augmented flight dynamics model, the optimal landing procedure of XV-15 tilt-rotor aircraft after one engine failure is formulated into a Nonlinear Optimal Control Problem(NOCP), solved by collocation and numerical optimization method. The time histories of pilot controls in cockpit during the optimal landing procedure are obtained for the evaluation of pilot workload. An evaluation method which can synthetically quantify the pilot workload in time and frequency domains is proposed with metrics of aggressiveness and cutoff frequencies of pilot controls. The scale of the pilot workload is compared with those of the shipboard landing procedures, bob-up/bob-down and dash/quickstop maneuvers of UH-60 helicopter. The results show that the aggressiveness of pilot collective and longitudinal controls for the tilt-rotor aircraft optimal landing procedure after one engine failure are higher than those for UH-60 helicopter shipboard landing procedures up to the condition of sea state 4, while the pilot cutoff frequency of collective control is lower than that of the bob-up/bob-down maneuver but the pilot cutoff frequency of longitudinal control is higher than that of the dash/quick-stop maneuver. The evaluated pilot workload level is between Cooper–Harper HQR Level 2 and Level 3.展开更多
Normally, cellular responses to modified siRNAs or new siRNA delivery systems have been studied in group cell behavior by PCR, western blotting and fluorescence microscopy. In this study, we present a novel high-conte...Normally, cellular responses to modified siRNAs or new siRNA delivery systems have been studied in group cell behavior by PCR, western blotting and fluorescence microscopy. In this study, we present a novel high-content screening （HCS） strategy to evaluate a novel delivery system （named CLD） of siRNA therapeutics, with which both the content of intracellular siRNAs and changes in protein expressing levels have been quantified in group cells and cellular population. We also observed that with the better cell uptake, CLD provided siRNA therapeutics （siBraf） better antitumor capability. This novel strategy was proved to be with efficiency, accuracy and high competency to adherent cell lines, thus making siRNA research more simplified.展开更多
With respect to the ergonomic evaluation and optimization in the mental task design of the aircraft cockpit display interface, the experimental measurement and theoretical modeling of mental workload were carried out ...With respect to the ergonomic evaluation and optimization in the mental task design of the aircraft cockpit display interface, the experimental measurement and theoretical modeling of mental workload were carried out under flight simulation task conditions using the performance evaluation, subjective evaluation and physiological measurement methods. The experimental results show that with an increased mental workload, the detection accuracy of flight operation significantly reduced and the reaction time was significantly prolonged; the standard deviation of R-R intervals（SDNN） significantly decreased, while the mean heart rate exhibited little change; the score of NASA_TLX scale significantly increased. On this basis, the indexes sensitive to mental workload were screened, and an integrated model for the discrimination and prediction of mental workload of aircraft cockpit display interface was established based on the Bayesian Fisher discrimination and classification method. The original validation and cross-validation methods were employed to test the accuracy of the results of discrimination and prediction of the integrated model, and the average prediction accuracies determined by these two methods are both higher than 85%. Meanwhile, the integrated model shows a higher accuracy in discrimination and prediction of mental workload compared with single indexes. The model proposed in this paper exhibits a satisfactory coincidence with the measured data and could accurately reflect the variation characteristics of the mental workload of aircraft cockpit display interface, thus providing a basis for the ergonomic evaluation and optimization design of the aircraft cockpit display interface in the future.展开更多
基金supported by the Transportation Science and Technology Program of Henan Province(grant number:2023-4-2)the Key Research and Development Program of Ningxia Science and Technology Department(grant number:2022BEG02008)+2 种基金China Communications Construction Group Co.,Ltd.Science and Technology R&D Project(grant number:2021KJW02)the Research and Development Program of Henan Transportation Investment Group Co.,Ltd.(grant number:HNJT2025-1-9)the Postdoctoral Fellowship Program of CPSF(grand number:GZC20251139).
文摘The addition of high-content crumb rubber(HCCR)in asphalt can effectively address waste tire pollution and provide sustainable environmental and economic advantages.However,the practical application of conventional rubberized binders is significantly limited by high viscosity and poor storage stability.To address these issues,researchers have pretreated crumb rubber(CR)with oil,but high-temperature performance remains insufficient.Therefore,this study aimed to optimize the viscosity,storage stability,and rheological properties of high-content crumb rubber-modified asphalt(HCCRMA)by varying the pretreatment levels of CR and incorporating various additives,including styrene-butadiene-styrene(SBS),deoiled asphalt(DA),or recycled low-density polyethylene(RLDPE).In addition,CR was pretreated with waste cooking oil(WCO)at various ratios,pre-swelling temperatures,and times.The results show that DA exhibits excellent storage stability and lower viscosity compared with other modifiers in HCCRMA,and the 4%RLDPE with pretreated HCCR has the greatest high-temperature rutting resistance.The inclusion of RLDPE increases the stiffness and elasticity of the modified asphalt,which results in greater high-temperature performance.Additionally,the fluorescence microscopy(FM)test confirms that SBS exhibits better dispersion than other modifiers and forms a more homogeneous phase separation in the HCCRMA.All in all,this research achieved an optimal balance of storage stability and rheological properties in asphalt modified with pretreated HCCR and 6%SBS,which provides a valuable reference for performance improvement of HCCR-modified binders.
文摘The rapid advent in artificial intelligence and big data has revolutionized the dynamic requirement in the demands of the computing resource for executing specific tasks in the cloud environment.The process of achieving autonomic resource management is identified to be a herculean task due to its huge distributed and heterogeneous environment.Moreover,the cloud network needs to provide autonomic resource management and deliver potential services to the clients by complying with the requirements of Quality-of-Service(QoS)without impacting the Service Level Agreements(SLAs).However,the existing autonomic cloud resource managing frameworks are not capable in handling the resources of the cloud with its dynamic requirements.In this paper,Coot Bird Behavior Model-based Workload Aware Autonomic Resource Management Scheme(CBBM-WARMS)is proposed for handling the dynamic requirements of cloud resources through the estimation of workload that need to be policed by the cloud environment.This CBBM-WARMS initially adopted the algorithm of adaptive density peak clustering for workloads clustering of the cloud.Then,it utilized the fuzzy logic during the process of workload scheduling for achieving the determining the availability of cloud resources.It further used CBBM for potential Virtual Machine(VM)deployment that attributes towards the provision of optimal resources.It is proposed with the capability of achieving optimal QoS with minimized time,energy consumption,SLA cost and SLA violation.The experimental validation of the proposed CBBMWARMS confirms minimized SLA cost of 19.21%and reduced SLA violation rate of 18.74%,better than the compared autonomic cloud resource managing frameworks.
基金supported by the National Natural Science Foundation of China (No. 11672128)
文摘An augmented flight dynamics model is developed to extend the existing flight dynamics model of tilt-rotor aircraft for optimal landing procedure analysis in the event of one engine failure.Compared with the existing flight dynamics model, the augmented model involves with more pilot control information in cockpit and is validated against the flight test data. Based on the augmented flight dynamics model, the optimal landing procedure of XV-15 tilt-rotor aircraft after one engine failure is formulated into a Nonlinear Optimal Control Problem(NOCP), solved by collocation and numerical optimization method. The time histories of pilot controls in cockpit during the optimal landing procedure are obtained for the evaluation of pilot workload. An evaluation method which can synthetically quantify the pilot workload in time and frequency domains is proposed with metrics of aggressiveness and cutoff frequencies of pilot controls. The scale of the pilot workload is compared with those of the shipboard landing procedures, bob-up/bob-down and dash/quickstop maneuvers of UH-60 helicopter. The results show that the aggressiveness of pilot collective and longitudinal controls for the tilt-rotor aircraft optimal landing procedure after one engine failure are higher than those for UH-60 helicopter shipboard landing procedures up to the condition of sea state 4, while the pilot cutoff frequency of collective control is lower than that of the bob-up/bob-down maneuver but the pilot cutoff frequency of longitudinal control is higher than that of the dash/quick-stop maneuver. The evaluated pilot workload level is between Cooper–Harper HQR Level 2 and Level 3.
基金Ministry of Science and Technology of China(Grant No.2012CB720604)NSFC(Grant No.20932001)
文摘Normally, cellular responses to modified siRNAs or new siRNA delivery systems have been studied in group cell behavior by PCR, western blotting and fluorescence microscopy. In this study, we present a novel high-content screening （HCS） strategy to evaluate a novel delivery system （named CLD） of siRNA therapeutics, with which both the content of intracellular siRNAs and changes in protein expressing levels have been quantified in group cells and cellular population. We also observed that with the better cell uptake, CLD provided siRNA therapeutics （siBraf） better antitumor capability. This novel strategy was proved to be with efficiency, accuracy and high competency to adherent cell lines, thus making siRNA research more simplified.
基金supported by the National Basic Research Program of China (No. 2010CB734104)
文摘With respect to the ergonomic evaluation and optimization in the mental task design of the aircraft cockpit display interface, the experimental measurement and theoretical modeling of mental workload were carried out under flight simulation task conditions using the performance evaluation, subjective evaluation and physiological measurement methods. The experimental results show that with an increased mental workload, the detection accuracy of flight operation significantly reduced and the reaction time was significantly prolonged; the standard deviation of R-R intervals（SDNN） significantly decreased, while the mean heart rate exhibited little change; the score of NASA_TLX scale significantly increased. On this basis, the indexes sensitive to mental workload were screened, and an integrated model for the discrimination and prediction of mental workload of aircraft cockpit display interface was established based on the Bayesian Fisher discrimination and classification method. The original validation and cross-validation methods were employed to test the accuracy of the results of discrimination and prediction of the integrated model, and the average prediction accuracies determined by these two methods are both higher than 85%. Meanwhile, the integrated model shows a higher accuracy in discrimination and prediction of mental workload compared with single indexes. The model proposed in this paper exhibits a satisfactory coincidence with the measured data and could accurately reflect the variation characteristics of the mental workload of aircraft cockpit display interface, thus providing a basis for the ergonomic evaluation and optimization design of the aircraft cockpit display interface in the future.
