期刊文献+
共找到730篇文章
< 1 2 37 >
每页显示 20 50 100
Multiple ionization of atoms and molecules impacted by very high-q fast projectiles in the strong coupling regime(q/v > 1)
1
作者 周满 邹贤容 +4 位作者 赵磊 陈熙萌 王诗尧 周旺 邵剑雄 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第10期252-256,共5页
In this paper, we present a simple theoretical approach to calculate the multiple ionization of big atoms and molecules induced by very high-q fast projectiles in a strong coupling regime (q/v 〉 1). The results obt... In this paper, we present a simple theoretical approach to calculate the multiple ionization of big atoms and molecules induced by very high-q fast projectiles in a strong coupling regime (q/v 〉 1). The results obtained from this approach are in excellent agreement with the available experimental data. A probable scenario of molecular multiple ionization by fast and very high-q projectiles is discussed. The very small computational time required here and the good agreement with the existing experimental data make it a good candidate for studying the multiple ionization of complex molecules under high linear energy transfers. 展开更多
关键词 multiple ionization high-q projectiles strong coupling regime model calculation
原文传递
High-Q cavity based on gradated one-dimensional photonic crystal
2
作者 高永浩 许兴胜 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第11期339-343,共5页
A high quality-factor (Q) cavity based on a one-dimensional (1D) photonic crystal with gradated elliptical holes was designed using FDTD simulation. Different gradient profiles of the mirror holes were found to co... A high quality-factor (Q) cavity based on a one-dimensional (1D) photonic crystal with gradated elliptical holes was designed using FDTD simulation. Different gradient profiles of the mirror holes were found to correspond to different Q- values of the cavities. A simple strategy is proposed to construct high-Q cavities by using an S-shaped gradient profile for the elliptical holes' minor axes, such as a cosine function or Gaussian function. Using such a strategy, a Q value exceeding two million is obtained with only ten mirror holes in a cavity. 展开更多
关键词 photonic crystal high-q cavity gradated cavities
原文传递
High-quality-factor space–time metasurface for free-space power isolation at near-infrared regime
3
作者 Raana Sabri Hossein Mosallaei 《Advanced Photonics Nexus》 2023年第6期83-95,共13页
Space–time metasurfaces are promising candidates for breaking Lorentz reciprocity,which constrains light propagation in numerous practical applications.There is a substantial difference between carrier and modulation... Space–time metasurfaces are promising candidates for breaking Lorentz reciprocity,which constrains light propagation in numerous practical applications.There is a substantial difference between carrier and modulation frequencies in space–time photonic metasurfaces that leads to negligible spatial pathway variation of light and weak nonreciprocal response.To surmount this obstacle,herein,the design principle of a high-quality-factor space–time gradient metasurface is demonstrated at the near-infrared regime that increases the lifetime of photons and allows for strong power isolation by lifting the adiabaticity of modulation.The all-dielectric metasurface consists of an array of silicon subwavelength gratings(SWGs)that are separated from distributed Bragg reflectors by a silica buffer.The resonant mode with ultrahigh quality-factor exceeding 10^(4)is excited within the SWG,which is characterized as magnetic octupole and features strong field localization.The SWGs are configured as multijunction p–n layers,whose multigate biasing with time-varying waveforms enables modulation of carriers in space and time.The proposed nonreciprocal metasurface is exploited for free-space optical power isolation by virtue of modulationinduced phase shift.It is shown that under time reversal and by interchanging the directions of incident and observation ports,power isolation of≈35 dB can be maintained between the two ports in free space. 展开更多
关键词 space-time metasurface high-q resonator optical nonreciprocity active photonic platform.
在线阅读 下载PDF
Q/V频段卫通地面站天线技术研究进展与分析
4
作者 张强 张一凡 《通信技术》 2026年第1期9-15,共7页
随着卫星通信向高通量、低时延方向演进,Q/V频段由于具有带宽高、抗干扰性强和高波束定向性的优势,将成为高通量卫星通信系统的核心频段。研究了Q/V频段反射面天线系统的主要组成与技术特性,总结了该频段国内外卫星组网发射、天线结构... 随着卫星通信向高通量、低时延方向演进,Q/V频段由于具有带宽高、抗干扰性强和高波束定向性的优势,将成为高通量卫星通信系统的核心频段。研究了Q/V频段反射面天线系统的主要组成与技术特性,总结了该频段国内外卫星组网发射、天线结构、跟踪接收、功率放大等器件领域的研究及应用进展,重点分析了高频段天线设计面临的关键技术挑战,包括路径损耗和雨衰、制造精度、稳定性等。此外,还探讨了各项技术发展的趋势,提出了未来重点研究和应用方向,包括新型材料应用、高集成度制造工艺优化、与6G技术融合等。通过研究国内外技术进展与应用动态,为该领域的技术研究和应用提供参考。 展开更多
关键词 Q/V频段 天线 高通量卫星通信 雨衰 星座
在线阅读 下载PDF
Visible Kerr comb generation in a high-Q silica microdisk resonator with a large wedge angle 被引量:7
5
作者 Jiyang Ma Longfu Xiao +5 位作者 Jiaxin Gu Hao Li Xinyu Cheng Guangqiang He Xiaoshun Jiang Min Xiao 《Photonics Research》 SCIE EI CSCD 2019年第5期573-578,共6页
This paper describes the specially designed geometry of a dry-etched large-wedge-angle silica microdisk resonator that enables anomalous dispersion in the 780 nm wavelength regime. This anomalous dispersion occurs nat... This paper describes the specially designed geometry of a dry-etched large-wedge-angle silica microdisk resonator that enables anomalous dispersion in the 780 nm wavelength regime. This anomalous dispersion occurs naturally without the use of a mode-hybridization technique to control the geometrical dispersion. By fabricating a1-μm-thick silica microdisk with a wedge angle as large as 56° and an optical Q-factor larger than 107, we achieve a visible Kerr comb that covers the wavelength interval of 700–897 nm. The wide optical frequency range and the closeness to the clock transition at 698 nm of 87 Sr atoms make our visible comb a potentially useful tool in optical atomic clock applications. 展开更多
关键词 COMB generation high-q SILICA MICRODISK RESONATOR LARGE wedge angle
原文传递
Observation of high-Q optomechanical modes in the mounted silica microspheres 被引量:5
6
作者 Zhen Shen Zhong-Hao Zhou +4 位作者 Chang-Ling Zou Fang-Wen Sun Guo-Ping Guo Chun-Hua Dong Guang-Can Guo 《Photonics Research》 SCIE EI 2015年第5期243-247,共5页
An efficient method to mount a coupled silica microsphere and tapered fiber system is proposed and demonstrated experimentally. For the purpose of optomechanical studies, high-quality-factor optical(Q_o~ 10~8) and me... An efficient method to mount a coupled silica microsphere and tapered fiber system is proposed and demonstrated experimentally. For the purpose of optomechanical studies, high-quality-factor optical(Q_o~ 10~8) and mechanical modes(Q_m~ 0.87 × 10~4) are maintained after the mounting process. For the mounted microsphere, the coupling system is more stable and compact and, thus, is beneficial for future studies and applications based on optomechanical interactions. Especially, the packaged optomechanical system, which is tested in a vacuum chamber,paves the way toward quantum optomechanics research in cryostat. 展开更多
关键词 MODE RATE Observation of high-q optomechanical modes in the mounted silica microspheres HIGH
原文传递
Bound states in the continuum and high-Q resonances supported by a dielectric ridge on a slab waveguide 被引量:4
7
作者 EVGENI A.BEZUS DMITRY A.BYKOV LEONID L.DOSKOLOVICH 《Photonics Research》 SCIE EI 2018年第11期1084-1093,共10页
We investigate the diffraction of the guided modes of a dielectric slab waveguide on a simple integrated structure consisting of a single dielectric ridge on the surface of the waveguide. Numerical simulations based o... We investigate the diffraction of the guided modes of a dielectric slab waveguide on a simple integrated structure consisting of a single dielectric ridge on the surface of the waveguide. Numerical simulations based on aperiodic rigorous coupled-wave analysis demonstrate the existence of sharp resonant features and bound states in the continuum(BICs) in the reflectance and transmittance spectra occurring at the oblique incidence of a transverseelectric(TE)-polarized guided mode on the ridge. Using the effective index method, we explain the resonances by the excitation of cross-polarized modes of the ridge. Formation of the BICs are confirmed using a theoretical model based on coupled-wave theory. The model suggests that the BICs occur due to the coupling of quasi-TE and quasi-transverse-magnetic modes of the structure. Simple analytical expressions for the angle of incidence and the ridge width predicting the location of the BICs are obtained. The existence of high-Q resonances and BICs enables using the considered integrated structure for sensing, transformation of optical signals, and enhancing nonlinear light–matter interactions. Due to the Lorentzian line shape of the resonances near the BICs, the structure is also promising for filtering applications. 展开更多
关键词 Bound states high-q RESONANCES SLAB waveguide TE BIC
原文传递
Simulating robust far-field coupling to traveling waves in large three-dimensional nanostructured high-Q microresonators 被引量:2
8
作者 LEI CHEN CHENG LI +2 位作者 YU-MIN LIU JUDITH SU EUAN MCLEOD 《Photonics Research》 SCIE EI CSCD 2019年第9期967-976,共10页
Ultra-high quality(Q) whispering gallery mode(WGM) microtoroid optical resonators have demonstrated highly sensitive biomolecular detection down to the single molecule limit;however, the lack of a robust coupling meth... Ultra-high quality(Q) whispering gallery mode(WGM) microtoroid optical resonators have demonstrated highly sensitive biomolecular detection down to the single molecule limit;however, the lack of a robust coupling method has prevented their widespread adoption outside the laboratory. We demonstrate through simulation that a phased array of nanorods can enable free-space coupling of light both into and out of a microtoroid while maintaining a high Q. To simulate large nanostructured WGM resonators, we developed a new approach known as FloWBEM,which is an efficient and compact 3D wedge model with custom boundary conditions that accurately simulate the resonant Fano interference between the traveling WGM waves and a nanorod array. Depending on the excitation conditions, we find loaded Q factors of the driven system as high as 2.1 × 10~7 and signal-to-background ratios as high as 3.86%, greater than the noise levels of many commercial detectors. These results can drive future experimental implementation. 展开更多
关键词 domain SIMULATING robust FAR-FIELD coupling to traveling waves in large THREE-DIMENSIONAL NANOSTRUCTURED high-q MICRORESONATORS WGM
原文传递
High-Q ring resonators directly written in As2S3 chalcogenide glass films 被引量:4
9
作者 Shahar Levy Matvei Klebanov Avi Zadok 《Photonics Research》 SCIE EI 2015年第3期63-67,共5页
Planar ring resonator waveguides are fabricated in thin films of As2S3 chalcogenide glass,deposited on silicaon-silicon substrates.Waveguide cores are directly written by scanning the focused illumination of a femtose... Planar ring resonator waveguides are fabricated in thin films of As2S3 chalcogenide glass,deposited on silicaon-silicon substrates.Waveguide cores are directly written by scanning the focused illumination of a femtosecond Ti:sapphire laser at a central wavelength of 810 nm,through a two-photon photo-darkening process.A large photoinduced index change of 0.3–0.4 refractive index units is obtained.The radius of the ring resonator is 1.9 mm,corresponding to a transmission free spectral range of 9.1 GHz.A high loaded(intrinsic) Q value of 110,000(180,000) is achieved.The thermal dependence of the resonator transfer function is characterized.The results provide the first report,to the best of our knowledge,of directly written high-Q ring resonators in chalcogenide glass films,and demonstrate the potential of this simple technique towards the fabrication of planar lightguide circuits in these materials. 展开更多
关键词 RING AS high-q ring resonators directly written in As2S3 chalcogenide glass films
原文传递
High-Q silica microdisk optical resonators with large wedge angles on a silicon chip 被引量:3
10
作者 Guanyu Li Pei Liu +4 位作者 Xiaoshun Jiang Chao Yang Jiyang Ma Hongya Wu Min Xiao 《Photonics Research》 SCIE EI 2015年第5期279-282,共4页
We experimentally demonstrate high optical quality factor silica microdisk resonators on a silicon chip with large wedge angles by reactive ion etching. For 2-μm-thick microresonators, we have achieved wedge angles o... We experimentally demonstrate high optical quality factor silica microdisk resonators on a silicon chip with large wedge angles by reactive ion etching. For 2-μm-thick microresonators, we have achieved wedge angles of 59°, 63°,70°, and 79° with optical quality factors of 2.4 × 10~7, 8.1 × 10~6, 5.9 × 10~6, and 7.4 × 10~6, respectively, from ~80 μm diameter microresonators in the 1550 nm wavelength band. Also, for 1-μm-thick microresonators, we have obtained an optical quality factor of 7.3 × 10~6 with a wedge angle of 74°. 展开更多
关键词 TE high high-q silica microdisk optical resonators with large wedge angles on a silicon chip mode
原文传递
All-dielectric terahertz metasurface governed by bound states in the continuum with high-Q factor 被引量:1
11
作者 Li Kun Zhao Xu +3 位作者 Wang Meng Jia Xingning Zhao Ruiqi Lu Guizhen 《The Journal of China Universities of Posts and Telecommunications》 EI CSCD 2024年第2期44-54,共11页
The method of terahertz(THz)resonance with a high-quality(high-Q)factor offers a vital physical mechanism for metasurface sensors and other high-Q factor applications.However,it is challenging to excite the resonance ... The method of terahertz(THz)resonance with a high-quality(high-Q)factor offers a vital physical mechanism for metasurface sensors and other high-Q factor applications.However,it is challenging to excite the resonance with a high-Q factor in metasurfaces with proper sensitivity as well as figure of merit(FOM)values.Here,an all-dielectric metasurface composed of two asymmetrical rectangular blocks is suggested.Quartz and silicon are the materials applied for the substrate and cuboids respectively.The distinct resonance governed by bound states in the continuum(BIC)is excited by forming an asymmetric cluster by a novel hybrid method of cutting and moving the cuboids.The investigation focuses on analyzing the transmission spectra of the metasurface under different variations in structural parameters and the loss of silicon refractive index.When the proposed defective metasurface serves as a transmittance sensor,it shows a Q factor of 1.08×10^(4)and achieves an FOM up to 4.8×10^(6),which is obtained under the asymmetric parameter equalling 1μm.Simultaneously,the proposed defective metasurface is sensitive to small changes in refractive index.When the thickness of the analyte is 180μm,the sensitivity reaches a maximum value of 578 GHz/RIU.Hence,the proposed defective metasurface exhibits an extensive number of possible applications in the filters,biomedical diagnosis,security screening,and so on. 展开更多
关键词 terahertz(THz)metasurface high-quality(high-q)factor bound states in the continuum figure of merit(FOM)
原文传递
c切Nd:YVO_(4)/Cr^(4+):YAG被动调Q 1064nm激光器实验研究
12
作者 胡千廷 付鑫鹏 +4 位作者 阮迪 潘禹轩 俞航航 孟诗涵 付喜宏 《发光学报》 北大核心 2026年第2期330-339,共10页
在第二阈值条件理论指导下,构建LD端面泵浦凹-平谐振腔,以1%(at.)c切Nd:YVO4为增益介质、初始透过率95.09%的Cr^(4+):YAG为可饱和吸收体(SA),系统优化输出镜透过率、腔长、准直聚焦镜焦距比与聚焦镜轴向位置等关键参数。实验结果表明,... 在第二阈值条件理论指导下,构建LD端面泵浦凹-平谐振腔,以1%(at.)c切Nd:YVO4为增益介质、初始透过率95.09%的Cr^(4+):YAG为可饱和吸收体(SA),系统优化输出镜透过率、腔长、准直聚焦镜焦距比与聚焦镜轴向位置等关键参数。实验结果表明,谐振腔的增益-损耗平衡主要由输出耦合透过率与腔长共同决定。腔长增大使重复频率下降、脉宽展宽,缩短聚焦镜焦距虽可提升重复频率但平均功率略降,聚焦位置存在单峰最优。在T_(OC)=14.2%、腔长12 mm、f_(1):f_(2)=10:6.43并精调聚焦位置条件下,在泵浦功率为1.9 W时获得平均功率501 mW、重复频率217 kHz、脉宽14.4 ns且时域抖动≤700 ns的稳定被动调Q输出。结论表明,第二阈值条件为Nd:YVO_(4)/Cr^(4+):YAG被动调Q激光器提供了清晰的设计与调参路径,通过匹配输出耦合、腔几何与模场尺寸、位置,可在确保SA快速漂白的同时高效提取能量,从而实现高重复频率、窄脉宽与低抖动的稳定输出。c切Nd:YVO4因受激发射截面较小、各向同性等特性,更易满足第二阈值并支撑高重复频率运转,相关结果可为精密加工、激光测距与非线性频率变换等应用提供依据。 展开更多
关键词 第二阈值条件 c切Nd:YVO_(4) 被动调Q 高重复频率
在线阅读 下载PDF
超高效液相色谱-高分辨质谱法测定聚合物稳定的垂直排列液晶中反应性单体的含量
13
作者 邸玉静 王伟 +9 位作者 张芳苗 牛晓珍 安险峰 龙志会 张军波 员国良 亢艳艳 王亚婷 王胜路 张莉 《分析试验室》 北大核心 2026年第1期106-110,共5页
建立了超高效液相色谱-四极杆/静电场轨道阱高分辨质谱法检验聚合物稳定的垂直排列液晶中的反应性单体。以Thermo Syncronis C18色谱柱为分析柱,乙腈及含有0.05%甲酸的水为流动相,梯度洗脱,在正离子模式下以全扫描模式采集分析,外标法... 建立了超高效液相色谱-四极杆/静电场轨道阱高分辨质谱法检验聚合物稳定的垂直排列液晶中的反应性单体。以Thermo Syncronis C18色谱柱为分析柱,乙腈及含有0.05%甲酸的水为流动相,梯度洗脱,在正离子模式下以全扫描模式采集分析,外标法定量。结果表明,反应性单体在3000~3600 mg/kg范围内线性关系良好,检出限为10 mg/kg,定量限为40 mg/kg。在低、高加标浓度下,聚合物稳定的垂直排列液晶中的反应性单体的回收率为99.6%~100.8%。日内相对标准偏差(RSD)为1%,日间RSD为5%。单因子试验分析结果表明,反应性单体含量显著影响峰面积响应信号。该方法可用于聚合物稳定的垂直排列液晶产品研发或品质控制各环节中的反应性单体的准确检测。 展开更多
关键词 聚合物稳定的垂直排列液晶 反应性单体 超高效液相色谱-四极杆/静电场轨道阱高分辨质谱
原文传递
基于UPLC-Q-Exactive Orbitrap MS分析泻白散在正常和慢性支气管炎小鼠体内的入血成分及其代谢差异
14
作者 彭鹏 李佳欣 +4 位作者 杨新月 刘方乐 祝晨蔯 林朝展 姚宇峰 《中国实验方剂学杂志》 北大核心 2026年第1期219-227,共9页
目的:利用超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-Q-Exactive Orbitrap MS),系统分析泻白散在正常状态和慢性支气管炎(CB)模型小鼠中的入血成分及其代谢轮廓,并比较两者之间的差异。方法30只雌性BABL/c小鼠随机分为正常... 目的:利用超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-Q-Exactive Orbitrap MS),系统分析泻白散在正常状态和慢性支气管炎(CB)模型小鼠中的入血成分及其代谢轮廓,并比较两者之间的差异。方法30只雌性BABL/c小鼠随机分为正常组、正常给药组、CB组、CB给药组和地塞米松组,每组6只。采用卵清蛋白(OVA)诱导建立CB小鼠模型。正常给药组和CB给药组小鼠于第21天开始灌胃泻白散(生药量13.2 g·kg^(-1)),地塞米松组小鼠同时灌胃地塞米松(0.5 mg·kg^(-1))直至第35天实验结束,随后采集血清样本经药效评价指标确定泻白散干预CB的药效作用。采用UPLC-Q-Exactive Orbitrap MS对泻白散的化学成分、入血成分及其代谢产物进行鉴定和分析,并结合化学计量法揭示泻白散在正常及CB状态下的代谢轮廓差异。同时,利用实时荧光定量聚合酶链式反应(Real-time PCR)检测肝脏关键代谢酶细胞色素P4502E1(CYP2E1)、细胞色素P4503A1(CYP3A1)、尿苷二磷酸葡萄糖醛酸基转移酶1A1(UGT1A1)和尿苷二磷酸葡萄糖醛酸基转移酶1A6(UGT1A6)酶的表达水平。结果在正常小鼠血清中,初步鉴定出泻白散的原型成分28个,代谢产物158个(包括Ⅰ相代谢产物48个和Ⅱ相代谢产物110个);在CB模型小鼠血清中,鉴定出原型成分32个,代谢产物178个(包括Ⅰ相代谢产物50个和Ⅱ相代谢产物128个)。其中,27个原型成分在2种状态下均被检出,主要包括12个黄酮类、2个生物碱类、3个三萜类、4个有机酸类、3个酰胺类、1个二苯乙烯类化合物和2个其他类化合物。化学计量分析表明,泻白散在正常和CB小鼠中的入血成分及其代谢产物的种类无明显差异,但其在CB小鼠体内的暴露量明显增加。与正常小鼠比较,CB小鼠体内泻白散的氧化、还原、甲基化等Ⅰ相代谢产物及葡萄糖醛酸化等Ⅱ相代谢产物的含量变化尤为显著。Real-time PCR结果显示,与正常组比较,CB小鼠肝脏中CYP2E1(P<0.05)、CYP3A1(P>0.05)、UGT1A1(P<0.01)和UGT1A6(P<0.01)的mRNA表达水平升高,这可能是导致代谢产物含量变化的主要原因。结论泻白散在正常和CB小鼠中的入血成分及其代谢轮廓存在明显差异,尤其Ⅰ相代谢中的氧化、还原、甲基化及Ⅱ相代谢中的葡萄糖醛酸化,且与肝脏中Ⅰ相和Ⅱ相代谢酶CYP2E1、CYP3A1、UGT1A1和UGT1A6表达水平升高密切相关。 展开更多
关键词 泻白散 入血成分 代谢轮廓 超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-Q-Exactive Orbitrap MS) 化学计量学 慢性支气管炎
原文传递
基于UPLC-Q-Orbitrap MS/MS分析栀子炒炭前后化学成分变化
15
作者 李兰 洪杰 +3 位作者 宋亚南 李一岚 王云 张村 《中国实验方剂学杂志》 北大核心 2026年第4期175-182,共8页
目的:探究栀子炒炭前后化学成分的变化规律,为栀子炒炭的物质基础研究提供数据支撑。方法:采用超高效液相色谱-四极杆-静电场轨道阱高分辨质谱(UPLC-Q-Orbitrap MS/MS)分别在正、负离子模式下采集数据,结合Compound Discoverer 3.3软件... 目的:探究栀子炒炭前后化学成分的变化规律,为栀子炒炭的物质基础研究提供数据支撑。方法:采用超高效液相色谱-四极杆-静电场轨道阱高分辨质谱(UPLC-Q-Orbitrap MS/MS)分别在正、负离子模式下采集数据,结合Compound Discoverer 3.3软件、在线数据库对生栀子和栀子炭中的化学成分进行全面分析,采用SIMCA14.1软件进行主成分分析及偏最小二乘法-判别分析,通过变量重要性投影(VIP)值>1筛选炒炭前后的差异次级代谢产物及初级代谢产物,并使用MetaboAnalyst网站分别进行京都基因与基因组百科全书(KEGG)通路富集,为阐明炮制机制提供参考。结果:共鉴定出185个成分,包括次级代谢产物成分96个,初级代谢产物成分89个;按类型分为以环烯醚萜苷类、黄酮类、萜类成分为主的九类成分,并对其裂解规律进行解析。同时,分别对次级代谢产物及初级代谢产物进行多元统计分析,鉴定出其差异代谢产物分别为70、59个,次级代谢产物共富集C5支链二元酸代谢及黄酮和黄酮醇生物合成途径等2条代谢通路,初级差异代谢产物共富集到亚油酸代谢、酪氨酸代谢等7条通路。结论:栀子炒炭后化学成分发生了明显变化,其中羟异栀子苷、西红花苷Ⅱ、藏红花酸、jasminoside B等环烯醚萜苷及萜类成分含量显著降低,4-羟基香豆素、京尼平苷酸、龙胆苦苷和山栀苷甲酯含量显著升高。推测该变化与炮制品增强的凉血止血功效相关。所辨识的关键成分为阐明栀子炒炭前后功效变化的物质基础提供了依据。 展开更多
关键词 栀子 栀子炭 化学成分 超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-Q-Orbitrap MS/MS) 初级代谢产物 次级代谢产物
原文传递
低频保护下的近地表Q补偿技术在川中叠前地震资料处理中的应用
16
作者 韩嵩 刘延利 +3 位作者 彭浩天 陈虹帆 曾鸣 张菽芮 《CT理论与应用研究(中英文)》 2026年第1期143-153,共11页
四川盆地川中须家河组近源成藏具有较大勘探潜力,但其储层类型多为薄层组合的孔隙裂缝性储层,储层纵横向非均质性强,河道砂体及小断层刻画不清晰,需要进行地震高分辨率处理;此外,须五段对于低频响应比较敏感,这就要求在保证全频处理的... 四川盆地川中须家河组近源成藏具有较大勘探潜力,但其储层类型多为薄层组合的孔隙裂缝性储层,储层纵横向非均质性强,河道砂体及小断层刻画不清晰,需要进行地震高分辨率处理;此外,须五段对于低频响应比较敏感,这就要求在保证全频处理的前提下,着重加强对低频信息的保护与拓展。针对该地质需求,开展低频保护下的近地表Q补偿技术的应用研究,以改善近地表的吸收衰减作用,增强子波的横向一致性,从而提升地震资料品质。首先,基于四川盆地近地表结构特征以及地震波衰减理论,利用表层旅行时,联合地震初至波主频等信息建立近地表Q场;然后,在传统稳定Q补偿的基础上,引入低频保护系数,提出低频保护下的稳定Q补偿流程。最后,对比分析理想主频、截止频率以及低频保护系数等参数对补偿效果的影响,确立该工区近地表补偿的最优参数组合。基于优选的参数组合对工区内的实际地震资料进行叠前道集补偿,补偿结果表明:基于该流程进行近地表Q补偿,可以有效地提高地震资料的分辨率,恢复砂体的振幅特征,改善同相轴的横向连续性;并且在拓展高频的同时,能够保持低频信息不被压制。使用处理后的资料提取的属性与工区内的实钻结果相吻合,显著提升了对砂体的刻画精度,为后续的油气勘探提供了坚实的数据支撑和技术保障。 展开更多
关键词 低频保护 近地表 Q补偿 高分辨率 一致性
原文传递
UPLC-Q-Orbitrap-MS法同时测定夏枯草配方颗粒中16种成分的含量
17
作者 华杰凯 张灿 +5 位作者 沈杰 庄俊嵘 王琴 常昕楠 刘伟 张建伟 《中成药》 北大核心 2026年第1期9-17,共9页
目的建立超高效液相色谱-四极杆-静电场轨道阱高分辨质谱(UPLC-Q-Orbitrap-MS)法同时测定夏枯草配方颗粒中奎宁酸、丹参素、原儿茶酸、原儿茶醛、咖啡酸、异迷迭香酸苷、迷迭香酸、新绿原酸、秦皮乙素、绿原酸、隐绿原酸、阿魏酸、水杨... 目的建立超高效液相色谱-四极杆-静电场轨道阱高分辨质谱(UPLC-Q-Orbitrap-MS)法同时测定夏枯草配方颗粒中奎宁酸、丹参素、原儿茶酸、原儿茶醛、咖啡酸、异迷迭香酸苷、迷迭香酸、新绿原酸、秦皮乙素、绿原酸、隐绿原酸、阿魏酸、水杨酸、异槲皮苷、金丝桃苷、芦丁的含量。方法分析采用ACQUITY UPLC BEH C_(18)色谱柱(2.1 mm×100 mm,1.7μm);流动相0.1%甲酸-甲醇,梯度洗脱;体积流量0.3 mL/min;柱温40℃;电喷雾离子源;正负离子扫描。再进行主成分分析、正交偏最小二乘判别分析。结果16种成分在各自范围内线性关系良好(R^(2)≥0.9977),平均加样回收率87.72%~111.52%,RSD 0.61%~11.99%。16批样品聚为4类,4个主成分累积方差贡献率为87.74%,丹参素、咖啡酸、异迷迭香酸苷、迷迭香酸、奎宁酸、金丝桃苷、芦丁、异槲皮苷、原儿茶醛、原儿茶酸为潜在质量标志物。结论该方法简便准确,稳定性好,可用于夏枯草饮片、配方颗粒的质量控制。 展开更多
关键词 夏枯草配方颗粒 化学成分 含量测定 超高效液相色谱-四极杆-静电场轨道阱高分辨质谱(UPLC-Q-Orbitrap-MS) 主成分分析 正交偏最小二乘判别分析
暂未订购
橡胶草化学成分鉴定及质谱裂解规律研究
18
作者 曾钰龙 董益阳 马强 《质谱学报》 北大核心 2026年第1期67-79,I0006,共14页
本研究采用超高效液相色谱-四极杆/静电场轨道阱高分辨质谱(UHPLC-Q/Orbitrap HRMS)法鉴定蒲公英属中草药橡胶草的化学成分。采用超声/微波辅助萃取技术提取橡胶草样品成分,通过ACQUITY UHPLC BEH C18色谱柱(150 mm×2.1 mm,1.7μm... 本研究采用超高效液相色谱-四极杆/静电场轨道阱高分辨质谱(UHPLC-Q/Orbitrap HRMS)法鉴定蒲公英属中草药橡胶草的化学成分。采用超声/微波辅助萃取技术提取橡胶草样品成分,通过ACQUITY UHPLC BEH C18色谱柱(150 mm×2.1 mm,1.7μm)进行液相色谱分离。采用电喷雾电离源正、负离子模式电离,四极杆/静电场轨道阱高分辨质谱仪检测数据,基于全扫描-数据依赖型二级质谱扫描(Full MS/dd-MS^(2))模式采集样品数据。原始数据采用Xcalibur 4.1软件进行色谱峰对齐和提取,将获得的前体离子和碎片离子的精确质量数信息与赛默飞中药成分高分辨质谱数据库(OTCML)、自建数据库和GNPS(Global Natural Products Social Molecular Networking)在线网站的数据库信息进行匹配,共鉴定出黄酮类、生物碱类、萜类、酚类、氨基酸类、苯丙素类、有机酸类、核苷酸类及其他类共94种化合物,并对部分典型化合物的质谱裂解规律进行解析,为阐明橡胶草非橡胶化学成分的药理作用提供科学依据。 展开更多
关键词 蒲公英橡胶草 超声/微波辅助萃取(UMAE) 超高效液相色谱-四极杆/静电场轨道阱高分辨质谱(UHPLC-Q/Orbitrap HRMS) 裂解规律
在线阅读 下载PDF
空天通信中动态资源分配算法
19
作者 施建锋 陆晨 李宝龙 《电讯技术》 北大核心 2026年第2期163-172,共10页
为满足空天网络中超可靠低时延通信需求,构建了低轨(Low Earth Orbit,LEO)卫星移动性模型和空天网络中舱内与舱外下行通信模型,在带宽敏感用户的容量约束和飞机的数据积压约束下,研究了最小化时延敏感用户平均传输时延的功率与信道资源... 为满足空天网络中超可靠低时延通信需求,构建了低轨(Low Earth Orbit,LEO)卫星移动性模型和空天网络中舱内与舱外下行通信模型,在带宽敏感用户的容量约束和飞机的数据积压约束下,研究了最小化时延敏感用户平均传输时延的功率与信道资源联合分配问题。针对该动态资源分配问题,提出了一种基于深度Q网络(Deep Q-network,DQN)的算法。该方法将强化学习与神经网络相结合,把LEO卫星子信道状态和舱内接入点的信道状态等网络状态作为状态空间,LEO卫星子信道的连接关系、LEO卫星的子信道功率分配和舱载用户的功率分配方案作为动作空间,时延敏感用户的平均传输时延作为奖励函数,根据动态环境自适应调整最优分配方案。仿真结果表明,在空天通信动态环境中,与传统算法相比,所提算法可降低15.4%的传输时延。 展开更多
关键词 低轨卫星通信 空天通信 高动态网络 动态资源分配 深度Q网络
在线阅读 下载PDF
基于谱效关系分析牡丹皮炭止血活性成分
20
作者 梁清光 林希光 孟江 《中国实验方剂学杂志》 北大核心 2026年第4期183-190,共8页
目的:基于牡丹皮炭指纹图谱与止血药效之间的谱效关系,寻找牡丹皮炭的主要止血活性成分,为明确牡丹皮炭止血活性成分提供依据。方法:采用超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-Q-Orbitrap MS/MS)建立16批牡丹皮炭水提... 目的:基于牡丹皮炭指纹图谱与止血药效之间的谱效关系,寻找牡丹皮炭的主要止血活性成分,为明确牡丹皮炭止血活性成分提供依据。方法:采用超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-Q-Orbitrap MS/MS)建立16批牡丹皮炭水提液的指纹图谱,确定共有峰。采用半自动凝血分析仪测定16批样品的体外凝血活性指标活化部分凝血活酶时间(APTT)。综合运用灰色关联度分析(GRA)、Pearson相关性分析及偏最小二乘回归分析(PLSR)筛选潜在的止血活性成分。对筛选出的活性成分,进一步通过体外凝血三项实验检测APTT、凝血酶原时间(PT)、凝血酶时间(TT),斑马鱼脑出血模型评价止血率及实时荧光定量聚合酶链式反应(Real-time PCR)检测凝血因子Ⅹ(FⅩ)mRNA表达水平,进行多维度药效验证。结果:成功建立了牡丹皮炭水提液的UPLC指纹图谱,标定12个共有峰,并通过UPLC-Q-Orbitrap MS/MS鉴定出其中9个化学成分。经GRA、Pearson相关性分析和PLSR筛选出5-羟甲基糠醛(5-HMF)、没食子酸、1-O-没食子酰葡萄糖和对羟基苯甲酸为牡丹皮炭的关键止血活性成分。体外凝血三项实验证实,该4种活性成分均能明显缩短APTT和PT(P<0.05,P<0.01)。斑马鱼脑出血模型进一步验证了其体内止血效果,各活性成分均能降低脑出血面积(P<0.05,P<0.01),5-HMF、没食子酸、1-O-没食子酰葡萄糖和对羟基苯甲酸止血率分别为31.20%、68.85%、45.45%和45.60%,且止血效果总体呈现浓度依赖性。Real-time PCR测表明,活性成分均可上调FⅩmRNA的表达水平(P<0.05,P<0.01),协同促进止血。结论:该研究通过整合谱效关系分析与多维度药效验证,从牡丹皮炭中筛选出4个止血活性成分,为阐明牡丹皮炭止血活物质基础提供科学依据。 展开更多
关键词 牡丹皮 炭药 谱效关系 止血活性成分 超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-QOrbitrap MS/MS)
原文传递
上一页 1 2 37 下一页 到第
使用帮助 返回顶部