A triaxial high-g accelerometer of microelectro mechanical systems （MEMS） has a struc- ture of multi-chips combination and will be used in aerospace field, civil and military fields. The ac- celerometer can measure ...A triaxial high-g accelerometer of microelectro mechanical systems （MEMS） has a struc- ture of multi-chips combination and will be used in aerospace field, civil and military fields. The ac- celerometer can measure the acceleration of the carrier. The chips with island-membrane structures on its back surfaces are made by MEMS dry processing. The chip is reasonable and can work well under high impact load; Titanium alloy base is also stronger in high shock environment, these are proved by finite element analysis. Finally, the MEMS combined triaxial high-g accelerometer is vali- dated by high impact calibration experiments in order to get a key performance index, including range, sensitivity and transverse sensitivity and so on. These data can satisfy the need of design but some problems remain, these will be eliminated by improvement of the processing technology and materials.展开更多
The behavior of resistance high-g impact of EMC （epoxy molding compound） with two package models, small outline package （POS） and Globtop, was evaluated by experimental method used Hopkinson bar. At 120,000 g （ge...The behavior of resistance high-g impact of EMC （epoxy molding compound） with two package models, small outline package （POS） and Globtop, was evaluated by experimental method used Hopkinson bar. At 120,000 g （generated in the Hopkinson bar with widths about 70 μs） no damage in either the POS devices or the Globtop devices was observed. In order to enhance the EMC＇s ability of resistance high-g impact, buffering effect of epoxy resin was also studied. The experimental results above all show that EMC has a better performance of impact resistance at about 120,000 g, and epoxy resin can absorb the stress wave to have the protected ability. The study of this paper could serve as a basis for selection packaging materials and enhance its reliability in high-g impact environment.展开更多
A high-g beam-mass structure accelerometer was designed.In this structure,by means of KOH back etching on the mass,V-groove structure was fabricated on the backside of the mass,so the weight of the mass and also the r...A high-g beam-mass structure accelerometer was designed.In this structure,by means of KOH back etching on the mass,V-groove structure was fabricated on the backside of the mass,so the weight of the mass and also the relative distance between the mass center and the neutral plane were all decreased.With the thin mass structure,we can take advantage of both beam-mass structure and flat film structure;the fabrication process is also simple.By means of Hopkinson shock test system,we did the accelerometer calibration.According to the test result,the sensitivity of the MEMS accelerometer is 0.71 μV/g,which keeps in accordance with the theoretical calculation.After a 200 000 g shocking test,the micro structure worked as usual,so this design can satisfy the requirements of high shock,seriously vibration test environment.展开更多
The wetting phenomenon of composite substrates in hypergravitational environment has a huge application in electronic devices and astronaut healthcare in aerospace missions.In the present contribution,the governing eq...The wetting phenomenon of composite substrates in hypergravitational environment has a huge application in electronic devices and astronaut healthcare in aerospace missions.In the present contribution,the governing equation of high-G droplets on the composite substrate is firstly established in the hypergravitational environment.Meanwhile,the apparent contact angles at the contact line between droplets and substrates with different stiffness gradients are achieved.Then,we analyze the effects of hypergravity factor and the substrate stiffness on the wetting profile of high-G droplets.By introducing the droplet volume and contact angle into the Bond number,the scaling law of the high-G droplet profile is established,and we find that the contact radius of the droplet R/S^(0.5)has a linear relationship withρω^(2)rl^(2)S/(γ_(LV)^(θ)),while the droplet height H/S^(0.5)has a power-law relationship withρω^(2)rl^(2)S/(γ_(LV)^(θ)).Finally,we explain the profiles of high-G droplets during the wetting process by illustrating energy components of the entire system and find that the substrate with positive triangular stiffness and inverted triangular stiffness show opposite evolution laws.On a substrate with inverted triangular stiffness,the gravitational potential energy is more dominant.展开更多
Driven by“More than Moore”,miniaturization and multifunctional integration of micro-energy devices are emerging as critical pathways for next-generation compact microsystems.This study proposes a sensing-in-Energy(S...Driven by“More than Moore”,miniaturization and multifunctional integration of micro-energy devices are emerging as critical pathways for next-generation compact microsystems.This study proposes a sensing-in-Energy(SiE)microdevice that immerses an inertial switch in a parallel-connected supercapacitor’s electrolyte,enabling simultaneous impact sensing and stable energy supply under extremely high gravitational acceleration(high-g)shocks(over 10,000 g).The SiE microdevice can be viewed as a high-amplitude shock sensor(raw signal peak>50 mV)under high-frequency perspective,and a shock-resistant electrochemical power source(voltage fluctuation<2%)under low-frequency perspective,while energy consumption reduces over 99.9%compared with conventional high-g sensor due to its event-driven mechanism.Sensing performance is boosted>50%using multiphysics model combined with machine learning algorithm.Furthermore,a fuze microsystem was built based on SiE microdevice,achieving 150μs-level ultrafast response.Three-layer penetration experiments have verified the engineering application of SiE microdevice and its fuze microsystem in smart munitions domains,providing a novel paradigm for heterogeneous microsystem in high-dynamic environments.展开更多
In this study, the discharge voltage behavior of electric double-layer capacitors （EDLCs） during high-g impact is studied both theoretically and experimentally. A micro-scale dynamic mechanism is proposed to describ...In this study, the discharge voltage behavior of electric double-layer capacitors （EDLCs） during high-g impact is studied both theoretically and experimentally. A micro-scale dynamic mechanism is proposed to describe the physical basis of the increase in the discharge voltage during a high-g impact. Based on this dynamic mechanism, a multi-field model is established, and the simulation and experimental studies of the discharge voltage increase phenomenon are conducted. From the simulation and experimental data, the relationship between the increased voltage and the high-g acceleration is revealed. An acceleration detection range of up to 10,000g is verified. The design of the device is optimized by studying the influences of the parameters, such as the electrode thickness and discharge current, on the outputs. This work opens up new avenues for the development of autonomous sensor systems based on energy storage devices and is significant for many practical applications such as in collision testing and automobile safety.展开更多
目的探究宫颈癌及癌前病变患者高危型人乳头瘤病毒(high-risk human papillomavirus,HR-HPV)感染现状及与血清人白细胞抗原-G(human leukocyte antigen-G,HLA-G)、高迁移率族蛋白A1(high mobility group protein A1,HMGA1)及转化生长因...目的探究宫颈癌及癌前病变患者高危型人乳头瘤病毒(high-risk human papillomavirus,HR-HPV)感染现状及与血清人白细胞抗原-G(human leukocyte antigen-G,HLA-G)、高迁移率族蛋白A1(high mobility group protein A1,HMGA1)及转化生长因子-β1(transforming growth factor-β1,TGF-β1)表达水平的相关性。方法选取2023年3月至2024年3月于重庆市开州区中医院接受治疗的148例宫颈癌患者,将其设为宫颈癌组,另选取同时期于医院接受治疗的92例宫颈上皮内瘤变(cervical intraepithelial neoplasias,CIN)患者,以及行健康体检的80例正常女性,分别将其设为癌前病变组和对照组。观察两组患者HR-HPV感染情况,以及三组受试者血清HLA-G、HMGA1、TGF-β1水平,同时分析血清HLA-G、HMGA1、TGF-β1水平与宫颈癌患者HR-HPV感染的相关性。结果癌前病变组中CINⅢ级HR-HPV感染率较CINⅠ级更高(χ^(2)=11.642,P=0.001),宫颈癌组子宫内膜癌的国际妇产科联盟(international federation of gynecology and obstetrics,FIGO)ⅠB期和FIGOⅡA期HR-HPV感染率均高于CINⅠ级、CINⅡ级和CINⅢ级(Z=22.045,Z=51.391,均P<0.001);宫颈癌组HR-HPV感染患者血清HLA-G、HMGA1、TGF-β1水平较非HR-HPV感染患者明显增高,癌前病变组HR-HPV感染患者血清HLA-G、HMGA1、TGF-β1水平高于非HR-HPV感染患者,差异均具有统计学意义(P<0.05)。宫颈癌组患者血清HLA-G、HMGA1、TGF-β1水平显著高于癌前病变组与对照组,癌前病变组患者血清HLA-G、HMGA1、TGF-β1水平高于对照组(P<0.05);通过Pearson相关系数分析得出,血清HLA-G、HMGA1、TGF-β1水平与宫颈癌患者HR-HPV感染均呈正相关(r=0.385,P<0.001;r=0.376,P<0.001;r=0.431,P<0.001)。结论宫颈癌与癌前病变患者HR-HPV感染率随病情进展升高,血清HLA-G、HMGA1、TGF-β1水平显著上调,且与HR-HPV感染密切相关,为宫颈癌的早期诊断等提供了新的生物标志物。展开更多
基金Supported by the National Natural Science Foundation of China(61273346)the National Defense Major Fundamental Research Program of China(20110003)+3 种基金the National Defense Key Fundamental Research Program of China(20132010)Specialized Research Fund for the Doctoral Program of Higher Education(20121101120009)Excellent Young Scholars Research Fund of Beijing Institute of Technology(2012YG0203)the Program for the Fundamental Research of Beijing Institute of Technology(2015CX02034)
文摘A triaxial high-g accelerometer of microelectro mechanical systems （MEMS） has a struc- ture of multi-chips combination and will be used in aerospace field, civil and military fields. The ac- celerometer can measure the acceleration of the carrier. The chips with island-membrane structures on its back surfaces are made by MEMS dry processing. The chip is reasonable and can work well under high impact load; Titanium alloy base is also stronger in high shock environment, these are proved by finite element analysis. Finally, the MEMS combined triaxial high-g accelerometer is vali- dated by high impact calibration experiments in order to get a key performance index, including range, sensitivity and transverse sensitivity and so on. These data can satisfy the need of design but some problems remain, these will be eliminated by improvement of the processing technology and materials.
基金Funded by the State Key Laboratory Foundation of China (No.9140C120704060C12)the Science and Technology Development Project of Universiti-esin of Shanxi Province
文摘The behavior of resistance high-g impact of EMC （epoxy molding compound） with two package models, small outline package （POS） and Globtop, was evaluated by experimental method used Hopkinson bar. At 120,000 g （generated in the Hopkinson bar with widths about 70 μs） no damage in either the POS devices or the Globtop devices was observed. In order to enhance the EMC＇s ability of resistance high-g impact, buffering effect of epoxy resin was also studied. The experimental results above all show that EMC has a better performance of impact resistance at about 120,000 g, and epoxy resin can absorb the stress wave to have the protected ability. The study of this paper could serve as a basis for selection packaging materials and enhance its reliability in high-g impact environment.
基金Shanxi province young leaders on science and by program for New Century Excellent Talents in University(NCET)
文摘A high-g beam-mass structure accelerometer was designed.In this structure,by means of KOH back etching on the mass,V-groove structure was fabricated on the backside of the mass,so the weight of the mass and also the relative distance between the mass center and the neutral plane were all decreased.With the thin mass structure,we can take advantage of both beam-mass structure and flat film structure;the fabrication process is also simple.By means of Hopkinson shock test system,we did the accelerometer calibration.According to the test result,the sensitivity of the MEMS accelerometer is 0.71 μV/g,which keeps in accordance with the theoretical calculation.After a 200 000 g shocking test,the micro structure worked as usual,so this design can satisfy the requirements of high shock,seriously vibration test environment.
基金supported by the National Natural Science Foundation of China(Grant Nos.12322206,12272340,and 11925206)Basic Science Center Program for Multiphase Media Evolution in Hypergravity of the National Natural Science Foundation of China(Grant No.51988101)the Zhejiang Provincial Natural Science Foundation of China(Grant No.LD21A020002).
文摘The wetting phenomenon of composite substrates in hypergravitational environment has a huge application in electronic devices and astronaut healthcare in aerospace missions.In the present contribution,the governing equation of high-G droplets on the composite substrate is firstly established in the hypergravitational environment.Meanwhile,the apparent contact angles at the contact line between droplets and substrates with different stiffness gradients are achieved.Then,we analyze the effects of hypergravity factor and the substrate stiffness on the wetting profile of high-G droplets.By introducing the droplet volume and contact angle into the Bond number,the scaling law of the high-G droplet profile is established,and we find that the contact radius of the droplet R/S^(0.5)has a linear relationship withρω^(2)rl^(2)S/(γ_(LV)^(θ)),while the droplet height H/S^(0.5)has a power-law relationship withρω^(2)rl^(2)S/(γ_(LV)^(θ)).Finally,we explain the profiles of high-G droplets during the wetting process by illustrating energy components of the entire system and find that the substrate with positive triangular stiffness and inverted triangular stiffness show opposite evolution laws.On a substrate with inverted triangular stiffness,the gravitational potential energy is more dominant.
基金granted by the Young Elite Scientists Sponsorship Program of CAST(No.2023QNRC001)the National Key Research and Development Program of China(No.2023YFB3211205).
文摘Driven by“More than Moore”,miniaturization and multifunctional integration of micro-energy devices are emerging as critical pathways for next-generation compact microsystems.This study proposes a sensing-in-Energy(SiE)microdevice that immerses an inertial switch in a parallel-connected supercapacitor’s electrolyte,enabling simultaneous impact sensing and stable energy supply under extremely high gravitational acceleration(high-g)shocks(over 10,000 g).The SiE microdevice can be viewed as a high-amplitude shock sensor(raw signal peak>50 mV)under high-frequency perspective,and a shock-resistant electrochemical power source(voltage fluctuation<2%)under low-frequency perspective,while energy consumption reduces over 99.9%compared with conventional high-g sensor due to its event-driven mechanism.Sensing performance is boosted>50%using multiphysics model combined with machine learning algorithm.Furthermore,a fuze microsystem was built based on SiE microdevice,achieving 150μs-level ultrafast response.Three-layer penetration experiments have verified the engineering application of SiE microdevice and its fuze microsystem in smart munitions domains,providing a novel paradigm for heterogeneous microsystem in high-dynamic environments.
文摘In this study, the discharge voltage behavior of electric double-layer capacitors （EDLCs） during high-g impact is studied both theoretically and experimentally. A micro-scale dynamic mechanism is proposed to describe the physical basis of the increase in the discharge voltage during a high-g impact. Based on this dynamic mechanism, a multi-field model is established, and the simulation and experimental studies of the discharge voltage increase phenomenon are conducted. From the simulation and experimental data, the relationship between the increased voltage and the high-g acceleration is revealed. An acceleration detection range of up to 10,000g is verified. The design of the device is optimized by studying the influences of the parameters, such as the electrode thickness and discharge current, on the outputs. This work opens up new avenues for the development of autonomous sensor systems based on energy storage devices and is significant for many practical applications such as in collision testing and automobile safety.
文摘目的探究宫颈癌及癌前病变患者高危型人乳头瘤病毒(high-risk human papillomavirus,HR-HPV)感染现状及与血清人白细胞抗原-G(human leukocyte antigen-G,HLA-G)、高迁移率族蛋白A1(high mobility group protein A1,HMGA1)及转化生长因子-β1(transforming growth factor-β1,TGF-β1)表达水平的相关性。方法选取2023年3月至2024年3月于重庆市开州区中医院接受治疗的148例宫颈癌患者,将其设为宫颈癌组,另选取同时期于医院接受治疗的92例宫颈上皮内瘤变(cervical intraepithelial neoplasias,CIN)患者,以及行健康体检的80例正常女性,分别将其设为癌前病变组和对照组。观察两组患者HR-HPV感染情况,以及三组受试者血清HLA-G、HMGA1、TGF-β1水平,同时分析血清HLA-G、HMGA1、TGF-β1水平与宫颈癌患者HR-HPV感染的相关性。结果癌前病变组中CINⅢ级HR-HPV感染率较CINⅠ级更高(χ^(2)=11.642,P=0.001),宫颈癌组子宫内膜癌的国际妇产科联盟(international federation of gynecology and obstetrics,FIGO)ⅠB期和FIGOⅡA期HR-HPV感染率均高于CINⅠ级、CINⅡ级和CINⅢ级(Z=22.045,Z=51.391,均P<0.001);宫颈癌组HR-HPV感染患者血清HLA-G、HMGA1、TGF-β1水平较非HR-HPV感染患者明显增高,癌前病变组HR-HPV感染患者血清HLA-G、HMGA1、TGF-β1水平高于非HR-HPV感染患者,差异均具有统计学意义(P<0.05)。宫颈癌组患者血清HLA-G、HMGA1、TGF-β1水平显著高于癌前病变组与对照组,癌前病变组患者血清HLA-G、HMGA1、TGF-β1水平高于对照组(P<0.05);通过Pearson相关系数分析得出,血清HLA-G、HMGA1、TGF-β1水平与宫颈癌患者HR-HPV感染均呈正相关(r=0.385,P<0.001;r=0.376,P<0.001;r=0.431,P<0.001)。结论宫颈癌与癌前病变患者HR-HPV感染率随病情进展升高,血清HLA-G、HMGA1、TGF-β1水平显著上调,且与HR-HPV感染密切相关,为宫颈癌的早期诊断等提供了新的生物标志物。
