A pregnant woman underwent fetal brain magnetic resonance imaging(MRI)following ultrasound detection of a posterior fossa cyst at 29 weeks'gestation.She presented with no relevant medical history and underwent a r...A pregnant woman underwent fetal brain magnetic resonance imaging(MRI)following ultrasound detection of a posterior fossa cyst at 29 weeks'gestation.She presented with no relevant medical history and underwent a routine obstetric examination during pregnancy.The fetal head position,fetal cranial development,and limb development remained normal until 29 weeks.展开更多
Objective:To present a rare case of glial heterotopia in the middle ear occurring in association with cholesteatoma.Patient and Intervention:A 56-year-old female presented with right-sided hearing loss and otorrhea.EN...Objective:To present a rare case of glial heterotopia in the middle ear occurring in association with cholesteatoma.Patient and Intervention:A 56-year-old female presented with right-sided hearing loss and otorrhea.ENT examination and CT imaging revealed middle ear cholesteatoma.Right canal wall down mastoidectomy with type Ⅲ tympanoplasty revealed a well-demarcated,soft,pinkish mass in the right middle ear without tegmen tympani dehiscence.Histopathological analysis confirmed glial heterotopia.Main Outcome Measures:Complete cholesteatoma resection,resolution of otorrhea,absence of neurological complications,and right-sided hearing improvement.Results:The patient demonstrated an uneventful postoperative recovery.At the five-month follow-up,tympanoplasty outcomes remained stable.Repeat imaging confirmed absence of skull base defects,with clinical resolution of otorrhea.No postoperative neurological complications(including cerebrospinal fluid leakage)were observed.Conclusions:Middle ear glial heterotopia is a rare entity that may be discovered incidentally or in association with infection/cholesteatoma.Definitive management requires surgical excision of the heterotopic tissue and concurrent repair of skull base bone defects when identified.Preoperative imaging evaluation with CT or MRI can be valuable to delineate anatomical relationships and exclude intracranial connections.展开更多
AIM:To evaluate magnetic resonance imaging(MRI) features of different types of gray matter heterotopia.METHODS:Between June 2005 and December 2009,the medical records and MRI studies of patients with gray matter heter...AIM:To evaluate magnetic resonance imaging(MRI) features of different types of gray matter heterotopia.METHODS:Between June 2005 and December 2009,the medical records and MRI studies of patients with gray matter heterotopia were reviewed.The MRI morphologic findings of heterotopia were recorded along with the presence and type of associated cranial malformations.Available clinical and electrophysiological data were also recorded.RESULTS:20 patients were included in the study.Their ages ranged from 9 mo to 39 years with a mean age of 15 years.All patients suffered from epileptic seizures.According to the location of heterotopia,patients were classified into three groups:subependymal(12),subcortical(5) and band(3) heterotopia.CONCLUSION:MRI was useful in diagnosing and differentiating between various types of gray matter heterotopia.The severity of clinical manifestations of heterotopia was related to the location and pattern of heterotopia.Determination of heterotopia type and its extent is useful for management planning and predicting prognosis.展开更多
The gallbladder is an unusual location of pancreatic heterotopia, defined as the presence of pancreatic tissue lacking anatomical and vascular continuity with the main body of the gland. A 28-year-old man presented wi...The gallbladder is an unusual location of pancreatic heterotopia, defined as the presence of pancreatic tissue lacking anatomical and vascular continuity with the main body of the gland. A 28-year-old man presented with anorexia, nausea and pain in the right upper abdomen. On physical examination, the abdomen was tender to palpation and Murphy sign was positive. The patient underwent a cholecystecomy. This case, in our opinion, is very interesting since it permits to consider a controversial issue in the pathology of the gallbladder. The histological appearance of ductal structure in pancreatic heterotopia resembles the histological picture of both Aschoff-Rokitansky （AR） sinuses and adenomyomas. This finding suggests that these lesions are linked by a common histogenetic origin. We suggest that the finding of an adenomyoma in the gallbladder should prompt an extensive sampling of the organ in order to verify the coexistence of pancreatic rests.展开更多
BACKGROUND Recently reported cases of pyogenic liver abscess associated with colonic cancer in the absence of underlying disease,have included a small number of cases of gastric heterotopia(GHT).GHT is a congenital an...BACKGROUND Recently reported cases of pyogenic liver abscess associated with colonic cancer in the absence of underlying disease,have included a small number of cases of gastric heterotopia(GHT).GHT is a congenital anomaly composed of ectopic gastric mucosa and can occur anywhere in the gastrointestinal tract but is more frequently encountered in the cervical esophagus.However,it is rarely observed in colon.Furthermore,most reported cases of GHT of the colon involved the rectum,and GHT involving the colon proximal to the rectum is rare.CASE SUMMARY An 83-year-old male patient presented with fever and a diagnosis of pyogenic liver abscess.Colonoscopy was performed for colon cancer workup and revealed a 1.0 cm sized polyp at the transverse colon.The polyp was removed by endoscopic mucosal resection by monopolar electrocauterization using a snare.Pathological examination revealed GHT.After administering intravenous antibiotics,the patient recovered well.CONCLUSION GHT in the colon could affect the development of pyogenic liver abscess by enabling hematogenous propagation of Klebsiella pneumoniae through mucosal damage.However,more study is needed due to the lack of cases.展开更多
Objective: This paper reports a rare case of nasal glial heterotopia presenting as sphenochoanal polyp. So far, literature has revealed only few cases. Case Report: A 55-year-old woman presented with a 2-month history...Objective: This paper reports a rare case of nasal glial heterotopia presenting as sphenochoanal polyp. So far, literature has revealed only few cases. Case Report: A 55-year-old woman presented with a 2-month history of left sided nasal obstruction. Rigid endoscopy showed greyish left nasal polyp and anterior discharge. Subsequently, CT scan of the sinuses revealed sphenochoanal polyp filling the left nasal cavity, without signs of expansion, or destruction and no obvious connection with intracranial tissue. Mass was removed endoscopically and histology confirmed glial nature of the mass. Conclusion: Any mass arising from sphenoid sinus should be carefully evaluated on CT scan for existence of fibrous stalk, or connection with brain tissue and needs to be considered in the differential diagnosis of the sphenochoanal mass. Complete surgical excision is the treatment of choice, which is curative.展开更多
Thyroid heterotopia is an abnormal localization of normal thyroid tissue coexisting with a normal organ and of normal localization. It is distinguished from ectopic thyroid and thyroid cancer metastasis. Lingual or su...Thyroid heterotopia is an abnormal localization of normal thyroid tissue coexisting with a normal organ and of normal localization. It is distinguished from ectopic thyroid and thyroid cancer metastasis. Lingual or sublingual thyroid is defined as the presence of thyroid tissue in the midline at the base of the tongue anywhere between the circumvallate papillae and the epiglottis. The prevalence of lingual thyroid is 1 in 100,000, and it is more common in women, with a female to male ratio ranging from 3:1 to 7:1. Embryologically, the thyroid originates at the foramen cecum, which is located at the junction of the anterior two thirds with the posterior one-third of the tongue, report a case of a goiter on a heterotopic basilingual thyroid tissue causing dysphagia in a 58-year-old woman operated in the ENT department of the CHN in Nouakchott, Mauritania, the thyroid origin of the mass was confirmed by histology.展开更多
Objective: To describe the radiological and pathological presentation of a salivary heterotopia in clivus. The lesion was detected incidentally in a 57-year-old woman. Material and Methods: Radiologic imaging (CT scan...Objective: To describe the radiological and pathological presentation of a salivary heterotopia in clivus. The lesion was detected incidentally in a 57-year-old woman. Material and Methods: Radiologic imaging (CT scan and MRI) and histological picture obtained from a clival lesion. Results: Radiologically the lesion presented as a well-limited lytic lesion with a diameter of 1.5 cm and accompanied by a cerebrospinal fluid secondary fistula. Histological examination revealed non-pathological salivary gland tissue. Conclusion: The differential diagnosis of this rare entity mandates a histological examination of the lesion.展开更多
Tess of D'Urbervilles is one of the Wessex novels of the late 19 thcentury naturalist writer, Thomas Hardy. The environment description has always been the focus of previous studies and critiques in that it plays ...Tess of D'Urbervilles is one of the Wessex novels of the late 19 thcentury naturalist writer, Thomas Hardy. The environment description has always been the focus of previous studies and critiques in that it plays a fundamental role in the characterization and the development of plot. While most of the studies consider the environment as an indicator and catalyst for the protagonists' tragedy, Foucault's philosophical theory concerning the Heterotopia actually provides us with a novel insight into the significance of the environment description in this story. In this perspective, the surroundings are not merely a physical existence entirely separated from human perceptive, but rather a synchronic space network where different spaces are intertwined and interlocked together.展开更多
Introduction:Nasal glial heterotopia is a rare congenital developmental disorder characterized by meningeal epithelium and/or glial components.Case presentation:A 2-month-old boy presented for treatment of a congenita...Introduction:Nasal glial heterotopia is a rare congenital developmental disorder characterized by meningeal epithelium and/or glial components.Case presentation:A 2-month-old boy presented for treatment of a congenital mass in the right nasal cavity near the pharynx.The preoperative diagnosis was congenital intranasal neoplasm.Nasal endoscopic resection of the nasopharyngeal mass was performed under general anesthesia.Histological findings in the resected tissue supported a diagnosis of intranasal glial heterotopia.The surgical outcome was good and no surgical site infection occurred.During 1 year of follow-up,the patient did not exhibit recurrence of heterotopia or related symptoms.Conclusion:Transnasal endoscopic surgery is recommended for patients with intranasal glial heterotopia.Thorough preoperative imaging should be performed before glioma resection.The mass should be differentiated from encephalocele to prevent cerebrospinal fluid leakage and meningitis.展开更多
基金supported by China Society for Maternal and Child Health Research(Grant/Award Number:2023CAMCHS003A17).
文摘A pregnant woman underwent fetal brain magnetic resonance imaging(MRI)following ultrasound detection of a posterior fossa cyst at 29 weeks'gestation.She presented with no relevant medical history and underwent a routine obstetric examination during pregnancy.The fetal head position,fetal cranial development,and limb development remained normal until 29 weeks.
基金supported by grants from National Natural Science Foundation of China(grant number.82301295)。
文摘Objective:To present a rare case of glial heterotopia in the middle ear occurring in association with cholesteatoma.Patient and Intervention:A 56-year-old female presented with right-sided hearing loss and otorrhea.ENT examination and CT imaging revealed middle ear cholesteatoma.Right canal wall down mastoidectomy with type Ⅲ tympanoplasty revealed a well-demarcated,soft,pinkish mass in the right middle ear without tegmen tympani dehiscence.Histopathological analysis confirmed glial heterotopia.Main Outcome Measures:Complete cholesteatoma resection,resolution of otorrhea,absence of neurological complications,and right-sided hearing improvement.Results:The patient demonstrated an uneventful postoperative recovery.At the five-month follow-up,tympanoplasty outcomes remained stable.Repeat imaging confirmed absence of skull base defects,with clinical resolution of otorrhea.No postoperative neurological complications(including cerebrospinal fluid leakage)were observed.Conclusions:Middle ear glial heterotopia is a rare entity that may be discovered incidentally or in association with infection/cholesteatoma.Definitive management requires surgical excision of the heterotopic tissue and concurrent repair of skull base bone defects when identified.Preoperative imaging evaluation with CT or MRI can be valuable to delineate anatomical relationships and exclude intracranial connections.
文摘AIM:To evaluate magnetic resonance imaging(MRI) features of different types of gray matter heterotopia.METHODS:Between June 2005 and December 2009,the medical records and MRI studies of patients with gray matter heterotopia were reviewed.The MRI morphologic findings of heterotopia were recorded along with the presence and type of associated cranial malformations.Available clinical and electrophysiological data were also recorded.RESULTS:20 patients were included in the study.Their ages ranged from 9 mo to 39 years with a mean age of 15 years.All patients suffered from epileptic seizures.According to the location of heterotopia,patients were classified into three groups:subependymal(12),subcortical(5) and band(3) heterotopia.CONCLUSION:MRI was useful in diagnosing and differentiating between various types of gray matter heterotopia.The severity of clinical manifestations of heterotopia was related to the location and pattern of heterotopia.Determination of heterotopia type and its extent is useful for management planning and predicting prognosis.
文摘The gallbladder is an unusual location of pancreatic heterotopia, defined as the presence of pancreatic tissue lacking anatomical and vascular continuity with the main body of the gland. A 28-year-old man presented with anorexia, nausea and pain in the right upper abdomen. On physical examination, the abdomen was tender to palpation and Murphy sign was positive. The patient underwent a cholecystecomy. This case, in our opinion, is very interesting since it permits to consider a controversial issue in the pathology of the gallbladder. The histological appearance of ductal structure in pancreatic heterotopia resembles the histological picture of both Aschoff-Rokitansky （AR） sinuses and adenomyomas. This finding suggests that these lesions are linked by a common histogenetic origin. We suggest that the finding of an adenomyoma in the gallbladder should prompt an extensive sampling of the organ in order to verify the coexistence of pancreatic rests.
文摘BACKGROUND Recently reported cases of pyogenic liver abscess associated with colonic cancer in the absence of underlying disease,have included a small number of cases of gastric heterotopia(GHT).GHT is a congenital anomaly composed of ectopic gastric mucosa and can occur anywhere in the gastrointestinal tract but is more frequently encountered in the cervical esophagus.However,it is rarely observed in colon.Furthermore,most reported cases of GHT of the colon involved the rectum,and GHT involving the colon proximal to the rectum is rare.CASE SUMMARY An 83-year-old male patient presented with fever and a diagnosis of pyogenic liver abscess.Colonoscopy was performed for colon cancer workup and revealed a 1.0 cm sized polyp at the transverse colon.The polyp was removed by endoscopic mucosal resection by monopolar electrocauterization using a snare.Pathological examination revealed GHT.After administering intravenous antibiotics,the patient recovered well.CONCLUSION GHT in the colon could affect the development of pyogenic liver abscess by enabling hematogenous propagation of Klebsiella pneumoniae through mucosal damage.However,more study is needed due to the lack of cases.
文摘Objective: This paper reports a rare case of nasal glial heterotopia presenting as sphenochoanal polyp. So far, literature has revealed only few cases. Case Report: A 55-year-old woman presented with a 2-month history of left sided nasal obstruction. Rigid endoscopy showed greyish left nasal polyp and anterior discharge. Subsequently, CT scan of the sinuses revealed sphenochoanal polyp filling the left nasal cavity, without signs of expansion, or destruction and no obvious connection with intracranial tissue. Mass was removed endoscopically and histology confirmed glial nature of the mass. Conclusion: Any mass arising from sphenoid sinus should be carefully evaluated on CT scan for existence of fibrous stalk, or connection with brain tissue and needs to be considered in the differential diagnosis of the sphenochoanal mass. Complete surgical excision is the treatment of choice, which is curative.
文摘Thyroid heterotopia is an abnormal localization of normal thyroid tissue coexisting with a normal organ and of normal localization. It is distinguished from ectopic thyroid and thyroid cancer metastasis. Lingual or sublingual thyroid is defined as the presence of thyroid tissue in the midline at the base of the tongue anywhere between the circumvallate papillae and the epiglottis. The prevalence of lingual thyroid is 1 in 100,000, and it is more common in women, with a female to male ratio ranging from 3:1 to 7:1. Embryologically, the thyroid originates at the foramen cecum, which is located at the junction of the anterior two thirds with the posterior one-third of the tongue, report a case of a goiter on a heterotopic basilingual thyroid tissue causing dysphagia in a 58-year-old woman operated in the ENT department of the CHN in Nouakchott, Mauritania, the thyroid origin of the mass was confirmed by histology.
文摘Objective: To describe the radiological and pathological presentation of a salivary heterotopia in clivus. The lesion was detected incidentally in a 57-year-old woman. Material and Methods: Radiologic imaging (CT scan and MRI) and histological picture obtained from a clival lesion. Results: Radiologically the lesion presented as a well-limited lytic lesion with a diameter of 1.5 cm and accompanied by a cerebrospinal fluid secondary fistula. Histological examination revealed non-pathological salivary gland tissue. Conclusion: The differential diagnosis of this rare entity mandates a histological examination of the lesion.
文摘Tess of D'Urbervilles is one of the Wessex novels of the late 19 thcentury naturalist writer, Thomas Hardy. The environment description has always been the focus of previous studies and critiques in that it plays a fundamental role in the characterization and the development of plot. While most of the studies consider the environment as an indicator and catalyst for the protagonists' tragedy, Foucault's philosophical theory concerning the Heterotopia actually provides us with a novel insight into the significance of the environment description in this story. In this perspective, the surroundings are not merely a physical existence entirely separated from human perceptive, but rather a synchronic space network where different spaces are intertwined and interlocked together.
文摘Introduction:Nasal glial heterotopia is a rare congenital developmental disorder characterized by meningeal epithelium and/or glial components.Case presentation:A 2-month-old boy presented for treatment of a congenital mass in the right nasal cavity near the pharynx.The preoperative diagnosis was congenital intranasal neoplasm.Nasal endoscopic resection of the nasopharyngeal mass was performed under general anesthesia.Histological findings in the resected tissue supported a diagnosis of intranasal glial heterotopia.The surgical outcome was good and no surgical site infection occurred.During 1 year of follow-up,the patient did not exhibit recurrence of heterotopia or related symptoms.Conclusion:Transnasal endoscopic surgery is recommended for patients with intranasal glial heterotopia.Thorough preoperative imaging should be performed before glioma resection.The mass should be differentiated from encephalocele to prevent cerebrospinal fluid leakage and meningitis.
