By employing the singular value decomposition(SVD) analysis, we have investigated in the present paper the covariations between circulation changes in the Northern(NH) and Southern Hemispheres(SH) and their associatio...By employing the singular value decomposition(SVD) analysis, we have investigated in the present paper the covariations between circulation changes in the Northern(NH) and Southern Hemispheres(SH) and their associations with ENSO by using the NCEP/NCAR reanalysis, the reconstructed monthly NOAA SST, and CMAP precipitation along with NOAA Climate Prediction Center(CPC) ENSO indices. A bi-hemispheric covariation mode(hereafter BHCM) is explored, which is well represented by the first mode of the SVD analysis of sea surface pressure anomaly(SLPA-SVD1). This SVD mode can explain 57.36% of the total covariance of SLPA. BHCM varies in time with a long-term trend and periodicities of 3—5 years. The long term trend revealed by SVD1 shows that the SLP increases in the equatorial central and eastern Pacific but decreases in the western Pacific and tropical Indian Ocean, which facilitates easterlies in the lower troposphere to be intensified and El Ni觡o events to occur with lower frequency. The spatial pattern of the BHCM looks roughly symmetric about the equator in the tropics, whereas it is characterized by zonal disturbances in the mid-latitude of NH and is highly associated with AAO in the mid-latitude of SH. On inter-annual time scales, the BHCM is highly correlated with ENSO. The atmosphere in both the NH and SH responds to sea surface temperature anomalies in the equatorial region, while the contemporaneous circulation changes in the NH and SH in turn affect the occurrence of El Ni觡o/La Ni觡a. In boreal winter, significant temperature and precipitation anomalies associated with the BHCM are found worldwide. Specifically, in the positive phase of the BHCM,temperature and precipitation are anomalously low in eastern China and some other regions of East Asia. These results are helpful for us to better understand interactions between circulations in the NH and SH and the dynamical mechanisms behind these interactions.展开更多
The carrier transport layer with reflection reduction morphology has attracted extensive attention for improving the utilization of light.Herein,we introduced single-layer hollow ZnO hemisphere arrays(ZHAs)behaving li...The carrier transport layer with reflection reduction morphology has attracted extensive attention for improving the utilization of light.Herein,we introduced single-layer hollow ZnO hemisphere arrays(ZHAs)behaving light trapping effect as the electron transport layer in perovskite photodetectors(PDs).The singlelayer hollow ZHAs can not only reduce the reflection,but also widen the angle of the effective incident light and especially transfer the distribution of the optical field from the ZnO/FTO interface to the perovskite active layer confirmed by the 3D finitedifference time-domain simulation.These merits benefit for the generation,transport and separation of carriers,improving the light utilization efficiency.Finally,our optimized FTO/ZHA/CsPbBr3/carbon structure PDs showed high self-powered performance with a linear dynamic range of 120.3 dB,a detectivity of 4.2×10^(12) Jones,rise/fall time of 13/28μs and the f_(−3) dB of up to 28 kHz.Benefiting from the high device performance,the PD was demonstrated to the application in the directional transmission of encrypted files as the signal receiving port with super high accuracy.This work uniquely utilizes the features of high-performance self-powered perovskite PDs in optical communication,paving the path to wide applications of all-inorganic perovskite PDs.展开更多
Cerebral ischemia not only causes pathological changes in the ischemic areas but also induces a series of secondary changes in more distal brain regions（such as the contralateral cerebral hemisphere）. The impact of ...Cerebral ischemia not only causes pathological changes in the ischemic areas but also induces a series of secondary changes in more distal brain regions（such as the contralateral cerebral hemisphere）. The impact of supratentorial lesions, which are the most common type of lesion, on the contralateral cerebellum has been studied in patients by positron emission tomography, single photon emission computed tomography, magnetic resonance imaging and diffusion tensor imaging. In the present study, we investigated metabolite changes in the contralateral cerebral hemisphere after supratentorial unilateral ischemia using nuclear magnetic resonance spectroscopy-based metabonomics. The permanent middle cerebral artery occlusion model of ischemic stroke was established in rats. Rats were randomly divided into the middle cerebral artery occlusion 1-, 3-, 9-and 24-hour groups and the sham group. ~1H nuclear magnetic resonance spectroscopy was used to detect metabolites in the left and right cerebral hemispheres. Compared with the sham group, the concentrations of lactate, alanine, γ-aminobutyric acid, choline and glycine in the ischemic cerebral hemisphere were increased in the acute stage, while the concentrations of N-acetyl aspartate, creatinine, glutamate and aspartate were decreased. This demonstrates that there is an upregulation of anaerobic glycolysis（shown by the increase in lactate）, a perturbation of choline metabolism（suggested by the increase in choline）, neuronal cell damage（shown by the decrease in N-acetyl aspartate） and neurotransmitter imbalance（evidenced by the increase in γ-aminobutyric acid and glycine and by the decrease in glutamate and aspartate） in the acute stage of cerebral ischemia. In the contralateral hemisphere, the concentrations of lactate, alanine, glycine, choline and aspartate were increased, while the concentrations of γ-aminobutyric acid, glutamate and creatinine were decreased. This suggests that there is a difference in the metabolite changes induced by ischemic injury in the contralateral and ipsilateral cerebral hemispheres. Our findings demonstrate the presence of characteristic changes in metabolites in the contralateral hemisphere and suggest that they are most likely caused by metabolic changes in the ischemic hemisphere.展开更多
The emissions of biophotons have been considered a ubiquitous property of living systems and their components. We measured the “spontaneous” photon emissions from fixed whole and sectioned human brains within hyper-...The emissions of biophotons have been considered a ubiquitous property of living systems and their components. We measured the “spontaneous” photon emissions from fixed whole and sectioned human brains within hyper-dark settings. Significant differences in photon counts were measured from different spatial planes. The flux densities were in the order of 2 × 10<sup>-12</sup> W per m<sup>2</sup>. The right hemispheres but not the left hemispheres displayed more photon emissions whose spectral power density profiles exhibited a conspicuous amplitude peak between 7.9 and 8 Hz. Brains measured in the hyperdark (~10<sup>-12</sup> W·m<sup>2</sup>) after removal from the typical lighting of the laboratory emitted more photons than those that had been maintained in the hyperdark for one week. The significant correlation between the numbers of photons emitted from the left hemisphere (but not the right) and global geomagnetic activity also exhibited energy equivalence between the photon flux densities and the geomagnetic shift within the cerebral volumes. These results indicate that what has been assumed to be fixed unresponsive human brain tissue still emits small numbers of photons that may be residuals from ambient light and can potentially interact with global geomagnetic activity. The medical implications for post-mortem intrinsic photonic information based upon the anisotropic microstructures within the hemispheres of the human cerebrum are discussed.展开更多
Natural convection heat transfer in open or closed cavities takes place in different engineering areas. The hemispherical cavity is a part of basic geometries although it is not widely studied. The present paper repor...Natural convection heat transfer in open or closed cavities takes place in different engineering areas. The hemispherical cavity is a part of basic geometries although it is not widely studied. The present paper reports the numerical study of natural convection in a closed hemispherical annulus delimited by two vertically eccentric hemispheres filled with Newtonian fluid (air in this case with <em>Pr</em> = 0.7) is conducted. The inner hemisphere is heated by a heat flux of constant density and the outer one is maintained isothermal. Based on the Boussinesq assumptions, the governing equations are numerically studied using unsteady natural convection formulated with vorticity and stream-function variables. These equations are written by using bispherical coordinates system and solved by using a finite difference method. The effect of the control parameters such as the Rayleigh number (<span style="white-space:nowrap;">10<sup>3</sup> ≤ <em>Ra</em> ≤ 10<sup>6</sup></span>) or the eccentricity (<em>e</em> = ±0.2, ±0.5, 0) in the dynamic and thermal behaviours of the fluid is investigated.展开更多
This study aimed to restore the ultimate strength of dented stainless-steel hemispheres with a radius of 90 mm and a thickness of 0.86 mm.All of the hemispheres were subjected to external hydrostatic pressure.Small st...This study aimed to restore the ultimate strength of dented stainless-steel hemispheres with a radius of 90 mm and a thickness of 0.86 mm.All of the hemispheres were subjected to external hydrostatic pressure.Small stainless-steel stiffened caps were used to eliminate the effect of indention on the ultimate strength.These caps had a radius of 36 mm,a thickness of 0.76 mm,and a height of 10.44 mm.Six hemispherical samples,including two intact hemispheres,two dented hemispheres without stiffening,and two dented hemispheres with stiffening,were prepared.Each hemi-sphere was geometrically measured for shape and thickness,hydrostatically tested for destruction,and numerically evaluated for comparison.The experimental and numerical data agreed well with each other.As a result,a spherical cap can effectively restore the ultimate strength of dented hemispheres under external hydrostatic pressure.The proposed restoration approach can be used to strengthen underwater pressure hulls with large local geometric imperfections.展开更多
This paper focusses on steel-welded hemispherical shells subjected to external hydrostatic pressure.The experimental and numerical investigations were performed to study their failure behaviour.The model was fabricate...This paper focusses on steel-welded hemispherical shells subjected to external hydrostatic pressure.The experimental and numerical investigations were performed to study their failure behaviour.The model was fabricated from mild steel and made through press forming and welding.We therefore considered the effect of initial shape imperfection,variation of thickness and residual stress obtained from the actual structures.Four hemisphere models designed with R/t from 50 to 130 were tested until failure.Prior to the test,the actual geometric imperfection and shell thickness were carefully measured.The comparisons of available design codes(PD 5500,ABS,DNV-GL)in calculating the collapse pressure were also highlighted against the available published test data on steel-welded hemispheres.Furthermore,the nonlinear FE simulations were also conducted to substantiate the ultimate load capacity and plastic deformation of the models that were tested.Parametric dependence of the level of sphericity,varying thickness and residual welding stresses were also numerically considered in the benchmark studies.The structure behaviour from the experiments was used to verify the numerical analysis.In this work,both collapse pressure and failure mode in the numerical model were consistent with the experimental model.展开更多
BACKGROUND： Certain neural functions, such as peripheral reflexes, differ between genders, while higher brain functions, such as language, are asymmetrically distributed between the two hemispheres. The question rema...BACKGROUND： Certain neural functions, such as peripheral reflexes, differ between genders, while higher brain functions, such as language, are asymmetrically distributed between the two hemispheres. The question remains as to whether depth perception differs between hemispheric laterality and genders, and whether it is affected by eye dominance. OBJECTIVE： To determine whether depth perception is influenced by factors such as gender, eye dominance, and hemispheric lateralization by recording evoked potential associated with depth perception. DESIGN, TIME AND SETTING： A contrast observation based on neuroelectrophysiology was performed at the Department of Biophysics of Ege University Medical School between June 2006 and April 2007. PARTICIPANTS： A total of 34 subjects, 19 females and 15 males, were included in the study with a mean age of （31.0 ± 6.9） years. All subjects were free of neurological or psychological disorders, or problems such as strabismus or vision correction. METHODS： Random-dot stereograms were used to elicit brain activity. A specially designed signal acquisition system employing two computers was used to record evoked potentials from both hemispheres via two pairs of scalp electrodes placed over the occipitotemporal areas of both hemispheres at symmetrical locations. MAIN OUTCOME MEASURES： Negative potential with a mean latency of （211.21 ±25.55） ms and a mean amplitude of （6.05 ± 1.53） pV was recorded from both occipitotemporal areas in 30 out of 34 participants. This was termed ＂Nd＂ and represented the evoked potential associated with depth perception. RESULTS： There were no significant differences in Nd amplitude or latency between the two hemispheres, the two eyes, or genders （P 〉 0.05）. CONCLUSION： The evoked potential associated with depth perception was not influenced by gender, hemisphere, or eye dominance.展开更多
The subject of natural convection heat transfer is motivated by a wide range of applications in engineering technology. The hemispherical cavity is a part of basic geometries although it is not widely studied. The eff...The subject of natural convection heat transfer is motivated by a wide range of applications in engineering technology. The hemispherical cavity is a part of basic geometries although it is not widely studied. The effect of inclinaison on natural convection fluid motions in the gap between two eccentric hemispheres is numerically studied. The inner hemisphere is subjected to a heat flux of a constant density and the outer one is maintened isothermal. The walls separating the two hemispheres are thermally adiabatic. Equations are formulated with vorticity and stream-functions variables. It is also assumed the fluid incompressible and obeys the approximation of Boussinesq. These equations are written by using bispherical coordinates system and solved by using a finite difference method. The results show the topology of flow is strongly dependent on the inclinaison because the flow can change from a unicellular regime to a multicellular regime by varying the inclination from 0 to π. By increasing the Rayleigh number (10<sup>3</sup><<i>Ra</i><10<sup>7</sup>), the flow intensifies. T<span style="letter-spacing:-0.05pt;">he results are shown in terms of streamlines and isotherms during th</span>eir transient evolution.展开更多
In terms of the expansion by extended empirical orthogonal function (EEOF) with data of ECMWF WMO and of outgoing longwave radiation(OLR) furnished by the NOAA polar-orbiting satellite,a study is made of November 1981...In terms of the expansion by extended empirical orthogonal function (EEOF) with data of ECMWF WMO and of outgoing longwave radiation(OLR) furnished by the NOAA polar-orbiting satellite,a study is made of November 1981 to March 1982 low-frequency (30--60 day)summer monsoon activity in the Indone- sian-North Australian zone (INAZ) together with its relation to atmospheric circulations in the Northern and Southern Hemispheres. Results show that at 850 hPa the southward blowing low-frequency NE(SW)wind from the eastern Asian coast changes, after crossing the euqator, to summer NW (SE) monsoon in the INAZ, which, when converging with (diverging from) the western-Australian enforced low-frequency SW (NE) wind, brings about strengthened (weakened) convection in the summer monsoon area and its eastward advance, with corresponding low- frequency variation shown in 850 hPa geopotential height. These outcomes are similar to those from the study of non-filtered actual observations, leading to the conclusion that the component of low-frequency variation illustrates major features characteristic of the variation in the tropical circulation.展开更多
Using the NCEP/NCAR reanalysis and the ENSO indices from the Climate Prediction Center over the period 1978-2014,we have investigated the contemporaneous circulation variations in the Northern and Southern Hemispheres...Using the NCEP/NCAR reanalysis and the ENSO indices from the Climate Prediction Center over the period 1978-2014,we have investigated the contemporaneous circulation variations in the Northern and Southern Hemispheres by performing the singular value decomposition analysis of sea level pressure anomalies（SLPA） after the ENSO signal is regressed out.It is found that there exists a polar-tropical seesaw mode（PTSM） that characterizes with the out of phase fluctuations of SLPA between the polar and tropical regions in the Northern and Southern Hemispheres in boreal winter.This PTSM explains 47.74%of the total covariance of SLPA and is almost independent of ENSO.It demonstrates a long-term trend and oscillation cycles of 2-3 and 4-6 yr.The long-term trend in PTSM indicates that the sea level pressure gradually decreases in the tropics and increases in the polar region with time.This PTSM looks roughly symmetric about the equator besides the seesaw pattern of SLPA between the tropics and polar region in each hemisphere.The disturbances in the geopotential height field in association with the PTSM shows baroclinic features in the tropics whereas equivalent barotropic features in the mid and high latitudes in the troposphere.The anomalous thermal forcing in the tropical region is possibly one of the factors facilitating the formation of this PTSM.Significant global precipitation and temperature anomalies related to the PTSM are observed.In the positive PTSM phase,precipitation and temperature are higher than normal in southern Europe and the Mediterranean and surrounding areas,but lower than normal in northern Europe and Siberia.Precipitation is higher than normal while temperature is lower than normal in Northeast Asia.Significant temperature and precipitation anomalies possibly occur in the regions of western China,northern India,parts of North America,parts of subtropical Africa,Maritime Continent,and Antarctic.These results are helpful for better understanding of the circulation variations and the mechanisms behind the interactions between the Northern and Southern Hemispheres and the related winter climate anomalies over globe.展开更多
This paper is a statistical survey of Southern Hemisphere cold and hot polar cap patches,in relation to the interplanetary magnetic field(IMF)and ionospheric convection geometry.A total of 11,946 patch events were ide...This paper is a statistical survey of Southern Hemisphere cold and hot polar cap patches,in relation to the interplanetary magnetic field(IMF)and ionospheric convection geometry.A total of 11,946 patch events were identified by Defense Meteorological Satellite Program(DMSP)F16 during the years 2011 to 2022.A temperature ratio of ion/electron temperature(T_(i)/T_(e))<0.68 is recommended to define a hot patch in the Southern Hemisphere,otherwise it is defined as a cold patch.The cold and hot patches have different dependencies on IMF clock angle,while their dependencies on IMF cone angle are similar.Both cold and hot patches appear most often on the duskside,and the distribution of cold patches gradually decreases from the dayside to the nightside,while hot patches have a higher occurrence rate near 14 and 21 magnetic local time(MLT).Moreover,we compared the key plasma characteristics of polar cap cold and hot patches in the Southern and Northern Hemispheres.The intensity of the duskside upward field-aligned current of patches in the Southern Hemisphere(SH)is stronger than that in the Northern Hemisphere(SH),which may be due to the discrepancy in conductivities between the two hemispheres,caused by the tilted dipole.In both hemispheres,the downward soft-electron energy flux of the dawnside patches is significantly greater than that of the duskside patches.展开更多
The snow density is a fundamental variable of the snow physical evolution processes,which can reflect the snowpack condition due to the thermal and gravitational compaction.Snow density is a bridge to transfer snow de...The snow density is a fundamental variable of the snow physical evolution processes,which can reflect the snowpack condition due to the thermal and gravitational compaction.Snow density is a bridge to transfer snow depth to snow water equivalent(SWE)for the snow water resources research.Therefore,it is important to understand the spatiotemporal distribution of snow density for the appropriate estimation of SWE.In this study,in situ snow densities from more than 6,000 stations in the Northern Hemisphere were used to analyze the spatial and temporal variations in snow density.The results displayed that snow density varied spatially and temporally in the Northern Hemisphere,with range of below 0.1 to over 0.4 g/cm^(3).The average snow densities in the mountainous regions of western North America,southeastern Canada,and Europe range from approximately 0.24 to 0.26 g/cm^(3),which is significantly greater than the values of 0.16–0.17 g/cm^(3)observed in Siberia,central Canada,the Great Plains of the United States,and China.The seasonal growth rates also present large spatial heterogeneity.The rates are over 0.024 g/cm^(3)per month in Southeastern Canada,the west mountain of North America and Europe,approximately 0.017 g/cm^(3)per month in Siberia,much larger than approximately 0.004 g/cm^(3)per month in other regions.Snow cover duration is a critical factor to determine the snow density.This study endorses the small snow density in China based on meteorological station observations,which results from that the meteorological stations are dominantly distributed in plain areas with relative short snow cover duration and shallow snow.展开更多
Introduction: Stroke is a worldwide leading cause of mortality and disability, and there are substantial economic costs for post-stroke. A large hemispheric ischemic stroke is a severe form of stroke that may occur in...Introduction: Stroke is a worldwide leading cause of mortality and disability, and there are substantial economic costs for post-stroke. A large hemispheric ischemic stroke is a severe form of stroke that may occur in up to 10% of stroke cases. In these cases, decompressive craniectomy (DC) is an effective strategy to reduce early case fatality. In this study, the authors present their experience in the management of large hemispheric stroke in patients who underwent decompressive craniectomy. Patients and Methods: This study is a retrospective analysis of 9 patients who underwent decompressive craniotomy for large hemispheric stroke from February 2021 to January 2024. Demographic, clinical, and radiologic variables were collected from the hospital archives. All patients underwent head CT scan or MRI showing the involvement of the majority or complete middle cerebral artery distribution area. Hemicraniectomy with duraplasty was the main surgical procedure. The mortality and the outcome using Modified Rankin Scale (mRS) were reported. Results: A total of 9 patients with large hemispheric stroke who underwent DC were reviewed retrospectively. The mean age was 53 years with extremes of 39- and 67-year-old. There were 6 males and 3 females. The main risk factors of stroke were hypertension and diabetes in 5 and 3 cases, respectively. The large craniectomy was made and the dura was opened in the stellate fashion. Duraplasty was performed using epicrane in 7 patients and fascia lata aponeurosis in 2 patients. In the postoperative course, 4 (44%) patients died in 1 month and the mortality rate was 66.6% in 6 months. Conclusion: Decompressive craniectomy is a life-saving procedure used to manage cerebral edema after stroke onset. In our study, the high mortality rate could be explained by many factors, such as patient selection criteria and timing of surgery. Early surgery within the first 48 hours in patients less than 60 years old with large hemispheric stroke is recommended.展开更多
BACKGROUND Currently,adolescent depression is one of the most significant public health concerns,markedly influencing emotional,cognitive,and social maturation.Despite advancements in distinguish the neurobiological s...BACKGROUND Currently,adolescent depression is one of the most significant public health concerns,markedly influencing emotional,cognitive,and social maturation.Despite advancements in distinguish the neurobiological substrates underlying depression,the intricate patterns of disrupted brain network connectivity in adolescents warrant further exploration.AIM To elucidate the neural correlates of adolescent depression by examining brain network connectivity using resting-state functional magnetic resonance imaging(rs-fMRI).METHODS The study cohort comprised 74 depressed adolescents and 59 healthy controls aged 12 to 17 years.Participants underwent rs-fMRI to evaluate functional connectivity within and across critical brain networks,including the visual,default mode network(DMN),dorsal attention,salience,somatomotor,and frontoparietal control networks.RESULTS Analyses revealed pronounced functional disparities within key neural circuits among adolescents with depression.The results demonstrated existence of hemispheric asymmetries characterized by enhanced activity in the left visual network,which contrasted the diminished activity in the right hemisphere.The DMN facilitated increased activity within the left prefrontal cortex and reduced engagement in the right hemisphere,implicating disrupted self-referential and emotional processing mechanisms.Additionally,an overactive right dorsal attention network and a hypoactive salience network were identified,underscoring significant abnormalities in attentional and emotional regulation in adolescent depression.CONCLUSION The findings from this study underscore distinct neural connectivity disruptions in adolescent depression,underscoring the critical role of specific neurobiological markers for precise early diagnosis of adolescent depression.The observed functional asymmetries and network-specific deviations elucidate the complex neurobiological architecture of adolescent depression,supporting the development of targeted therapeutic strategies.展开更多
Climate change is having an increasing impact on coastal infrastructure,leading to more frequent and intensified wave activity,including higher waves driven by typhoons and abnormal sea conditions.Consequently,issues ...Climate change is having an increasing impact on coastal infrastructure,leading to more frequent and intensified wave activity,including higher waves driven by typhoons and abnormal sea conditions.Consequently,issues related to the stability of existing port structures,such as caissons,have become a significant concern.In particular,gravity-type caisson on the land side of coastal port structures require enhanced stability and safety.Gravity-type caissons,which resist external forces through their own weight,are highly vulnerable to functional failures,such as sliding displacement,triggered by abnormal waves shifting specific caissons.The destruction of caisson and quay walls can lead to substantial recovery costs,necessitating improvements in caisson stability to address the challenges posed by increased wave forces and changes in port logistics due to larger vessels.One approach to enhancing caisson stability is the use of long caissons.Long caisson is commonly used where a breakwater is needed to withstand wave action and distribute forces evenly along a length of breakwater.The construction of caissons faces challenges due to limitations on the size of individual units imposed by construction conditions,launching methods,and marine crane requirements.Therefore,connecting multiple caissons to form long caissons presents a viable alternative.This study suggested two connection methods for long caissons.The first method was a hemisphere caisson,which allows the connection parts to seat against each other under self-weight during construction.The second method was a displacement-allowing connection utilizing rubble(embedded rebar connection within riprap connection).This approach allows some displacement while employing rebar to resist excessive deformation,thereby dispersing the resulting wave forces to adjacent caissons.Performance comparisons between the developed connections and conventional gravity-type caissons were conducted using a finite element analysis model.The results indicate that the proposed connections demonstrate improved resistance to wave forces compared to traditional caissons without such connections.Further studies should include field applications and performance evaluations of various caisson sizes under different environmental and geological conditions.展开更多
Based on the elastoplastic mechanical properties of the weld and heat affected zone metals obtained by a nanoindentation test, a theoretical calculation model was established for the forming limit diagram（FLD） of ta...Based on the elastoplastic mechanical properties of the weld and heat affected zone metals obtained by a nanoindentation test, a theoretical calculation model was established for the forming limit diagram（FLD） of tailor-welded blanks（TWBs） on the basis of plastic constitutive relations and Hosford yield criteria. Hemispherical punch bulging tests were performed to verify the FLD theoretical calculation results. The results demonstrated that not only the FLD theoretical calculation of base materials but also that of TWBs had a good agreement with their experiments. Besides, poorer formability of TWBs caused its FLD significantly lower than that of base materials. The theoretical calculation model offers a reliable approach to obtain the specific FLD of TWBs.展开更多
BACKGROUND Wernicke's encephalopathy is a disease caused by thiamine deficiency.The lesions usually involve the periphery of the aqueduct,midbrain,tectum,third ventricle,papillary body,and thalamus.It is very rare...BACKGROUND Wernicke's encephalopathy is a disease caused by thiamine deficiency.The lesions usually involve the periphery of the aqueduct,midbrain,tectum,third ventricle,papillary body,and thalamus.It is very rare to affect the vermis and cerebellar hemispheres.CASE SUMMARY We report a 77-year-old female patient admitted to the emergency department of our hospital for 2 d of unconsciousness.Brain magnetic resonance imaging showed increased diffusion weighted imaging signals in the bilateral thalamus,periventricular regions of the third ventricle,corpora quadrigemina,vermis,and cerebellar hemispheres.Wernicke's encephalopathy was considered.She was given thiamine therapy and became conscious after the treatment.CONCLUSION Wernicke's encephalopathy may have various imaging manifestations.Clinicians should keep in mind that Wernicke’s encephalopathy may occur in patients who experience prolonged periods of malnutrition.展开更多
A scheme of hemispherical hot cavity solid ion source with electron impact is brought up. Sample evaporation and ionization is accomplished in the quasi-tight hemispherical cavity. The two axial designed holes are use...A scheme of hemispherical hot cavity solid ion source with electron impact is brought up. Sample evaporation and ionization is accomplished in the quasi-tight hemispherical cavity. The two axial designed holes are used to lead electrons into the cavity and to draw ions out of it. The area of two holes takes up only 1/150 of whole cavity's surface area. Sample atoms after evaporation will go through many times of sticking, desorption, release and finally diffuse out of the cavity and be partly ionized. The flying direction of atoms and ions in cavity points to the cavity center. Electrons from ring cathode are focused into the cavity by electrostatic field without magnet. The hemispherical cavity was heated by axis current which forms a centripetal field to drift ions in cavity. In the area close to the cavity center, ions will be drawn out and focused to a point. The atom's ionization efficiency, the ion's extracting performance, the fractionation and chemistry selectivity, and the applicable scope about this ion source are discussed.展开更多
The enrichment by highly information load of the school educational process, which leads in severe environment to psycho-emotional stress, confirms the necessity of studying the psycho-emotional and physiological stab...The enrichment by highly information load of the school educational process, which leads in severe environment to psycho-emotional stress, confirms the necessity of studying the psycho-emotional and physiological stability of the senior schoolboys to information educational stress in rugged climate/geographic regions of Siberia. Observed were the 110 teenagers, the inhabitants of Novosibirsk, the students of 9th-10th classes of the special lycée. Clinical, psychological, psychophysiological, biochemical and hormonal methods of observation were used. It was shown that efficiency of the modern information-enriched educational process defines a complex of individual adaptive characteristics of an organism, including lateral phenotype of the prevalence of cerebral hemispheres, the stability of psychophysiological response, minimization of painful reaction to sharp changes of the factors of nature—meteosensitivity, and also the belonging to chronotypes (morning or evening). These features form the basis of stability of the young organism to the educational information stress and to the action of rugged climate-meteorological and biorhytmological factors, aggravating this stress.展开更多
基金National Natural Science Foundation of China(4133042541175062)
文摘By employing the singular value decomposition(SVD) analysis, we have investigated in the present paper the covariations between circulation changes in the Northern(NH) and Southern Hemispheres(SH) and their associations with ENSO by using the NCEP/NCAR reanalysis, the reconstructed monthly NOAA SST, and CMAP precipitation along with NOAA Climate Prediction Center(CPC) ENSO indices. A bi-hemispheric covariation mode(hereafter BHCM) is explored, which is well represented by the first mode of the SVD analysis of sea surface pressure anomaly(SLPA-SVD1). This SVD mode can explain 57.36% of the total covariance of SLPA. BHCM varies in time with a long-term trend and periodicities of 3—5 years. The long term trend revealed by SVD1 shows that the SLP increases in the equatorial central and eastern Pacific but decreases in the western Pacific and tropical Indian Ocean, which facilitates easterlies in the lower troposphere to be intensified and El Ni觡o events to occur with lower frequency. The spatial pattern of the BHCM looks roughly symmetric about the equator in the tropics, whereas it is characterized by zonal disturbances in the mid-latitude of NH and is highly associated with AAO in the mid-latitude of SH. On inter-annual time scales, the BHCM is highly correlated with ENSO. The atmosphere in both the NH and SH responds to sea surface temperature anomalies in the equatorial region, while the contemporaneous circulation changes in the NH and SH in turn affect the occurrence of El Ni觡o/La Ni觡a. In boreal winter, significant temperature and precipitation anomalies associated with the BHCM are found worldwide. Specifically, in the positive phase of the BHCM,temperature and precipitation are anomalously low in eastern China and some other regions of East Asia. These results are helpful for us to better understand interactions between circulations in the NH and SH and the dynamical mechanisms behind these interactions.
基金the National Natural Science Foundation of China(Nos.51972101,11874143)the Natural Science Foundation of Hubei Province(No.2019CFB508)the Application Fundamental Research Project of Wuhan Science and Technology Bureau(No.2019010701011396).
文摘The carrier transport layer with reflection reduction morphology has attracted extensive attention for improving the utilization of light.Herein,we introduced single-layer hollow ZnO hemisphere arrays(ZHAs)behaving light trapping effect as the electron transport layer in perovskite photodetectors(PDs).The singlelayer hollow ZHAs can not only reduce the reflection,but also widen the angle of the effective incident light and especially transfer the distribution of the optical field from the ZnO/FTO interface to the perovskite active layer confirmed by the 3D finitedifference time-domain simulation.These merits benefit for the generation,transport and separation of carriers,improving the light utilization efficiency.Finally,our optimized FTO/ZHA/CsPbBr3/carbon structure PDs showed high self-powered performance with a linear dynamic range of 120.3 dB,a detectivity of 4.2×10^(12) Jones,rise/fall time of 13/28μs and the f_(−3) dB of up to 28 kHz.Benefiting from the high device performance,the PD was demonstrated to the application in the directional transmission of encrypted files as the signal receiving port with super high accuracy.This work uniquely utilizes the features of high-performance self-powered perovskite PDs in optical communication,paving the path to wide applications of all-inorganic perovskite PDs.
基金supported by grants from the Health Innovation Talents Project of Zhejiang Province of China,No.2016the National Natural Science Foundation of China,No.81571626,U1404823+2 种基金the Natural Science Foundation of Zhejiang Province of China,No.LY15H220001the Medical and Health Research Project of Zhejiang Province of China,No.2014KYA134the Wenzhou Bureau of Science and Technology of China,No.Y20140731,Y20150087
文摘Cerebral ischemia not only causes pathological changes in the ischemic areas but also induces a series of secondary changes in more distal brain regions（such as the contralateral cerebral hemisphere）. The impact of supratentorial lesions, which are the most common type of lesion, on the contralateral cerebellum has been studied in patients by positron emission tomography, single photon emission computed tomography, magnetic resonance imaging and diffusion tensor imaging. In the present study, we investigated metabolite changes in the contralateral cerebral hemisphere after supratentorial unilateral ischemia using nuclear magnetic resonance spectroscopy-based metabonomics. The permanent middle cerebral artery occlusion model of ischemic stroke was established in rats. Rats were randomly divided into the middle cerebral artery occlusion 1-, 3-, 9-and 24-hour groups and the sham group. ~1H nuclear magnetic resonance spectroscopy was used to detect metabolites in the left and right cerebral hemispheres. Compared with the sham group, the concentrations of lactate, alanine, γ-aminobutyric acid, choline and glycine in the ischemic cerebral hemisphere were increased in the acute stage, while the concentrations of N-acetyl aspartate, creatinine, glutamate and aspartate were decreased. This demonstrates that there is an upregulation of anaerobic glycolysis（shown by the increase in lactate）, a perturbation of choline metabolism（suggested by the increase in choline）, neuronal cell damage（shown by the decrease in N-acetyl aspartate） and neurotransmitter imbalance（evidenced by the increase in γ-aminobutyric acid and glycine and by the decrease in glutamate and aspartate） in the acute stage of cerebral ischemia. In the contralateral hemisphere, the concentrations of lactate, alanine, glycine, choline and aspartate were increased, while the concentrations of γ-aminobutyric acid, glutamate and creatinine were decreased. This suggests that there is a difference in the metabolite changes induced by ischemic injury in the contralateral and ipsilateral cerebral hemispheres. Our findings demonstrate the presence of characteristic changes in metabolites in the contralateral hemisphere and suggest that they are most likely caused by metabolic changes in the ischemic hemisphere.
文摘The emissions of biophotons have been considered a ubiquitous property of living systems and their components. We measured the “spontaneous” photon emissions from fixed whole and sectioned human brains within hyper-dark settings. Significant differences in photon counts were measured from different spatial planes. The flux densities were in the order of 2 × 10<sup>-12</sup> W per m<sup>2</sup>. The right hemispheres but not the left hemispheres displayed more photon emissions whose spectral power density profiles exhibited a conspicuous amplitude peak between 7.9 and 8 Hz. Brains measured in the hyperdark (~10<sup>-12</sup> W·m<sup>2</sup>) after removal from the typical lighting of the laboratory emitted more photons than those that had been maintained in the hyperdark for one week. The significant correlation between the numbers of photons emitted from the left hemisphere (but not the right) and global geomagnetic activity also exhibited energy equivalence between the photon flux densities and the geomagnetic shift within the cerebral volumes. These results indicate that what has been assumed to be fixed unresponsive human brain tissue still emits small numbers of photons that may be residuals from ambient light and can potentially interact with global geomagnetic activity. The medical implications for post-mortem intrinsic photonic information based upon the anisotropic microstructures within the hemispheres of the human cerebrum are discussed.
文摘Natural convection heat transfer in open or closed cavities takes place in different engineering areas. The hemispherical cavity is a part of basic geometries although it is not widely studied. The present paper reports the numerical study of natural convection in a closed hemispherical annulus delimited by two vertically eccentric hemispheres filled with Newtonian fluid (air in this case with <em>Pr</em> = 0.7) is conducted. The inner hemisphere is heated by a heat flux of constant density and the outer one is maintained isothermal. Based on the Boussinesq assumptions, the governing equations are numerically studied using unsteady natural convection formulated with vorticity and stream-function variables. These equations are written by using bispherical coordinates system and solved by using a finite difference method. The effect of the control parameters such as the Rayleigh number (<span style="white-space:nowrap;">10<sup>3</sup> ≤ <em>Ra</em> ≤ 10<sup>6</sup></span>) or the eccentricity (<em>e</em> = ±0.2, ±0.5, 0) in the dynamic and thermal behaviours of the fluid is investigated.
基金This work was financially supported by the National Natural Science Foundation of China(Grant Nos.52071160 and 52071203)the National Natural Science Foundation of Jiangsu Province(Grant Nos.BK20190103 and BK20190964)the Six Talent Peaks Project of Jiangsu Province(Grant No.KTHY-068).
文摘This study aimed to restore the ultimate strength of dented stainless-steel hemispheres with a radius of 90 mm and a thickness of 0.86 mm.All of the hemispheres were subjected to external hydrostatic pressure.Small stainless-steel stiffened caps were used to eliminate the effect of indention on the ultimate strength.These caps had a radius of 36 mm,a thickness of 0.76 mm,and a height of 10.44 mm.Six hemispherical samples,including two intact hemispheres,two dented hemispheres without stiffening,and two dented hemispheres with stiffening,were prepared.Each hemi-sphere was geometrically measured for shape and thickness,hydrostatically tested for destruction,and numerically evaluated for comparison.The experimental and numerical data agreed well with each other.As a result,a spherical cap can effectively restore the ultimate strength of dented hemispheres under external hydrostatic pressure.The proposed restoration approach can be used to strengthen underwater pressure hulls with large local geometric imperfections.
基金The corresponding author would like to acknowledge the Research Grant of Pukyong National University(2019).
文摘This paper focusses on steel-welded hemispherical shells subjected to external hydrostatic pressure.The experimental and numerical investigations were performed to study their failure behaviour.The model was fabricated from mild steel and made through press forming and welding.We therefore considered the effect of initial shape imperfection,variation of thickness and residual stress obtained from the actual structures.Four hemisphere models designed with R/t from 50 to 130 were tested until failure.Prior to the test,the actual geometric imperfection and shell thickness were carefully measured.The comparisons of available design codes(PD 5500,ABS,DNV-GL)in calculating the collapse pressure were also highlighted against the available published test data on steel-welded hemispheres.Furthermore,the nonlinear FE simulations were also conducted to substantiate the ultimate load capacity and plastic deformation of the models that were tested.Parametric dependence of the level of sphericity,varying thickness and residual welding stresses were also numerically considered in the benchmark studies.The structure behaviour from the experiments was used to verify the numerical analysis.In this work,both collapse pressure and failure mode in the numerical model were consistent with the experimental model.
文摘BACKGROUND： Certain neural functions, such as peripheral reflexes, differ between genders, while higher brain functions, such as language, are asymmetrically distributed between the two hemispheres. The question remains as to whether depth perception differs between hemispheric laterality and genders, and whether it is affected by eye dominance. OBJECTIVE： To determine whether depth perception is influenced by factors such as gender, eye dominance, and hemispheric lateralization by recording evoked potential associated with depth perception. DESIGN, TIME AND SETTING： A contrast observation based on neuroelectrophysiology was performed at the Department of Biophysics of Ege University Medical School between June 2006 and April 2007. PARTICIPANTS： A total of 34 subjects, 19 females and 15 males, were included in the study with a mean age of （31.0 ± 6.9） years. All subjects were free of neurological or psychological disorders, or problems such as strabismus or vision correction. METHODS： Random-dot stereograms were used to elicit brain activity. A specially designed signal acquisition system employing two computers was used to record evoked potentials from both hemispheres via two pairs of scalp electrodes placed over the occipitotemporal areas of both hemispheres at symmetrical locations. MAIN OUTCOME MEASURES： Negative potential with a mean latency of （211.21 ±25.55） ms and a mean amplitude of （6.05 ± 1.53） pV was recorded from both occipitotemporal areas in 30 out of 34 participants. This was termed ＂Nd＂ and represented the evoked potential associated with depth perception. RESULTS： There were no significant differences in Nd amplitude or latency between the two hemispheres, the two eyes, or genders （P 〉 0.05）. CONCLUSION： The evoked potential associated with depth perception was not influenced by gender, hemisphere, or eye dominance.
文摘The subject of natural convection heat transfer is motivated by a wide range of applications in engineering technology. The hemispherical cavity is a part of basic geometries although it is not widely studied. The effect of inclinaison on natural convection fluid motions in the gap between two eccentric hemispheres is numerically studied. The inner hemisphere is subjected to a heat flux of a constant density and the outer one is maintened isothermal. The walls separating the two hemispheres are thermally adiabatic. Equations are formulated with vorticity and stream-functions variables. It is also assumed the fluid incompressible and obeys the approximation of Boussinesq. These equations are written by using bispherical coordinates system and solved by using a finite difference method. The results show the topology of flow is strongly dependent on the inclinaison because the flow can change from a unicellular regime to a multicellular regime by varying the inclination from 0 to π. By increasing the Rayleigh number (10<sup>3</sup><<i>Ra</i><10<sup>7</sup>), the flow intensifies. T<span style="letter-spacing:-0.05pt;">he results are shown in terms of streamlines and isotherms during th</span>eir transient evolution.
基金The study is jointly supported by National Natural Science Foundation of Chinathe State Meteorological Administration Monsoon Research Funds.
文摘In terms of the expansion by extended empirical orthogonal function (EEOF) with data of ECMWF WMO and of outgoing longwave radiation(OLR) furnished by the NOAA polar-orbiting satellite,a study is made of November 1981 to March 1982 low-frequency (30--60 day)summer monsoon activity in the Indone- sian-North Australian zone (INAZ) together with its relation to atmospheric circulations in the Northern and Southern Hemispheres. Results show that at 850 hPa the southward blowing low-frequency NE(SW)wind from the eastern Asian coast changes, after crossing the euqator, to summer NW (SE) monsoon in the INAZ, which, when converging with (diverging from) the western-Australian enforced low-frequency SW (NE) wind, brings about strengthened (weakened) convection in the summer monsoon area and its eastward advance, with corresponding low- frequency variation shown in 850 hPa geopotential height. These outcomes are similar to those from the study of non-filtered actual observations, leading to the conclusion that the component of low-frequency variation illustrates major features characteristic of the variation in the tropical circulation.
基金Supported by the National Natural Science Foundation of China(41175062 and 41330425)Science Innovation Program of the State Key Laboratory of Severe Weather,Chinese Academy of Meteorological Sciences(2015LASW-A03)
文摘Using the NCEP/NCAR reanalysis and the ENSO indices from the Climate Prediction Center over the period 1978-2014,we have investigated the contemporaneous circulation variations in the Northern and Southern Hemispheres by performing the singular value decomposition analysis of sea level pressure anomalies（SLPA） after the ENSO signal is regressed out.It is found that there exists a polar-tropical seesaw mode（PTSM） that characterizes with the out of phase fluctuations of SLPA between the polar and tropical regions in the Northern and Southern Hemispheres in boreal winter.This PTSM explains 47.74%of the total covariance of SLPA and is almost independent of ENSO.It demonstrates a long-term trend and oscillation cycles of 2-3 and 4-6 yr.The long-term trend in PTSM indicates that the sea level pressure gradually decreases in the tropics and increases in the polar region with time.This PTSM looks roughly symmetric about the equator besides the seesaw pattern of SLPA between the tropics and polar region in each hemisphere.The disturbances in the geopotential height field in association with the PTSM shows baroclinic features in the tropics whereas equivalent barotropic features in the mid and high latitudes in the troposphere.The anomalous thermal forcing in the tropical region is possibly one of the factors facilitating the formation of this PTSM.Significant global precipitation and temperature anomalies related to the PTSM are observed.In the positive PTSM phase,precipitation and temperature are higher than normal in southern Europe and the Mediterranean and surrounding areas,but lower than normal in northern Europe and Siberia.Precipitation is higher than normal while temperature is lower than normal in Northeast Asia.Significant temperature and precipitation anomalies possibly occur in the regions of western China,northern India,parts of North America,parts of subtropical Africa,Maritime Continent,and Antarctic.These results are helpful for better understanding of the circulation variations and the mechanisms behind the interactions between the Northern and Southern Hemispheres and the related winter climate anomalies over globe.
基金supported by the National Natural Science Foundation of China(Grants 42325404,42120104003,42204164,42474219 and U22A2006)the Chinese Meridian Project,the International Partnership Program of Chinese Academy of Sciences(Grant 183311KYSB20200003)+7 种基金Shandong Provincial Natural Science Foundation(Grants ZR2022QD077,ZR2022MD034)the Stable-Support Scientific Project of China Research Institute of Radiowave Propagation(Grant A132312191)the foundation of the National Key Laboratory of Electromagnetic Environment(Grant 6142403180204)the Chongqing Natural Science Foundation(Grants cstc2021ycjh-bgzxm0072,CSTB2023NSCQ-LZX0082)National Program on Key Basic Research Project(Grant 2022173-SD-1)The work in Norway is supported by the Research Council of Norway Grant 326039Work at UCLA has been supported by NSF grant AGS-2055192This research was supported by the International Space Science Institute(ISSI)in Bern and Beijing,through ISSI International Team project#511(Multi-Scale Magnetosphere-Ionosphere-Thermosphere Interaction).
文摘This paper is a statistical survey of Southern Hemisphere cold and hot polar cap patches,in relation to the interplanetary magnetic field(IMF)and ionospheric convection geometry.A total of 11,946 patch events were identified by Defense Meteorological Satellite Program(DMSP)F16 during the years 2011 to 2022.A temperature ratio of ion/electron temperature(T_(i)/T_(e))<0.68 is recommended to define a hot patch in the Southern Hemisphere,otherwise it is defined as a cold patch.The cold and hot patches have different dependencies on IMF clock angle,while their dependencies on IMF cone angle are similar.Both cold and hot patches appear most often on the duskside,and the distribution of cold patches gradually decreases from the dayside to the nightside,while hot patches have a higher occurrence rate near 14 and 21 magnetic local time(MLT).Moreover,we compared the key plasma characteristics of polar cap cold and hot patches in the Southern and Northern Hemispheres.The intensity of the duskside upward field-aligned current of patches in the Southern Hemisphere(SH)is stronger than that in the Northern Hemisphere(SH),which may be due to the discrepancy in conductivities between the two hemispheres,caused by the tilted dipole.In both hemispheres,the downward soft-electron energy flux of the dawnside patches is significantly greater than that of the duskside patches.
基金funded by the National Natural Science Foundation of China(Grant Nos:42125604&42171143)the Second Tibetan Plateau Scientific Expedition and Research Program(STEP)(Grant No.2019QZKK0201)。
文摘The snow density is a fundamental variable of the snow physical evolution processes,which can reflect the snowpack condition due to the thermal and gravitational compaction.Snow density is a bridge to transfer snow depth to snow water equivalent(SWE)for the snow water resources research.Therefore,it is important to understand the spatiotemporal distribution of snow density for the appropriate estimation of SWE.In this study,in situ snow densities from more than 6,000 stations in the Northern Hemisphere were used to analyze the spatial and temporal variations in snow density.The results displayed that snow density varied spatially and temporally in the Northern Hemisphere,with range of below 0.1 to over 0.4 g/cm^(3).The average snow densities in the mountainous regions of western North America,southeastern Canada,and Europe range from approximately 0.24 to 0.26 g/cm^(3),which is significantly greater than the values of 0.16–0.17 g/cm^(3)observed in Siberia,central Canada,the Great Plains of the United States,and China.The seasonal growth rates also present large spatial heterogeneity.The rates are over 0.024 g/cm^(3)per month in Southeastern Canada,the west mountain of North America and Europe,approximately 0.017 g/cm^(3)per month in Siberia,much larger than approximately 0.004 g/cm^(3)per month in other regions.Snow cover duration is a critical factor to determine the snow density.This study endorses the small snow density in China based on meteorological station observations,which results from that the meteorological stations are dominantly distributed in plain areas with relative short snow cover duration and shallow snow.
文摘Introduction: Stroke is a worldwide leading cause of mortality and disability, and there are substantial economic costs for post-stroke. A large hemispheric ischemic stroke is a severe form of stroke that may occur in up to 10% of stroke cases. In these cases, decompressive craniectomy (DC) is an effective strategy to reduce early case fatality. In this study, the authors present their experience in the management of large hemispheric stroke in patients who underwent decompressive craniectomy. Patients and Methods: This study is a retrospective analysis of 9 patients who underwent decompressive craniotomy for large hemispheric stroke from February 2021 to January 2024. Demographic, clinical, and radiologic variables were collected from the hospital archives. All patients underwent head CT scan or MRI showing the involvement of the majority or complete middle cerebral artery distribution area. Hemicraniectomy with duraplasty was the main surgical procedure. The mortality and the outcome using Modified Rankin Scale (mRS) were reported. Results: A total of 9 patients with large hemispheric stroke who underwent DC were reviewed retrospectively. The mean age was 53 years with extremes of 39- and 67-year-old. There were 6 males and 3 females. The main risk factors of stroke were hypertension and diabetes in 5 and 3 cases, respectively. The large craniectomy was made and the dura was opened in the stellate fashion. Duraplasty was performed using epicrane in 7 patients and fascia lata aponeurosis in 2 patients. In the postoperative course, 4 (44%) patients died in 1 month and the mortality rate was 66.6% in 6 months. Conclusion: Decompressive craniectomy is a life-saving procedure used to manage cerebral edema after stroke onset. In our study, the high mortality rate could be explained by many factors, such as patient selection criteria and timing of surgery. Early surgery within the first 48 hours in patients less than 60 years old with large hemispheric stroke is recommended.
基金Supported by the Medical Research Project of the Chongqing Municipal Health Commission,No.2024WSJK110.
文摘BACKGROUND Currently,adolescent depression is one of the most significant public health concerns,markedly influencing emotional,cognitive,and social maturation.Despite advancements in distinguish the neurobiological substrates underlying depression,the intricate patterns of disrupted brain network connectivity in adolescents warrant further exploration.AIM To elucidate the neural correlates of adolescent depression by examining brain network connectivity using resting-state functional magnetic resonance imaging(rs-fMRI).METHODS The study cohort comprised 74 depressed adolescents and 59 healthy controls aged 12 to 17 years.Participants underwent rs-fMRI to evaluate functional connectivity within and across critical brain networks,including the visual,default mode network(DMN),dorsal attention,salience,somatomotor,and frontoparietal control networks.RESULTS Analyses revealed pronounced functional disparities within key neural circuits among adolescents with depression.The results demonstrated existence of hemispheric asymmetries characterized by enhanced activity in the left visual network,which contrasted the diminished activity in the right hemisphere.The DMN facilitated increased activity within the left prefrontal cortex and reduced engagement in the right hemisphere,implicating disrupted self-referential and emotional processing mechanisms.Additionally,an overactive right dorsal attention network and a hypoactive salience network were identified,underscoring significant abnormalities in attentional and emotional regulation in adolescent depression.CONCLUSION The findings from this study underscore distinct neural connectivity disruptions in adolescent depression,underscoring the critical role of specific neurobiological markers for precise early diagnosis of adolescent depression.The observed functional asymmetries and network-specific deviations elucidate the complex neurobiological architecture of adolescent depression,supporting the development of targeted therapeutic strategies.
基金supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(Nos.RS-2023-00212586 and RS-2024-00348557)the Korea Maritime&Ocean University Research Fund in 2024.
文摘Climate change is having an increasing impact on coastal infrastructure,leading to more frequent and intensified wave activity,including higher waves driven by typhoons and abnormal sea conditions.Consequently,issues related to the stability of existing port structures,such as caissons,have become a significant concern.In particular,gravity-type caisson on the land side of coastal port structures require enhanced stability and safety.Gravity-type caissons,which resist external forces through their own weight,are highly vulnerable to functional failures,such as sliding displacement,triggered by abnormal waves shifting specific caissons.The destruction of caisson and quay walls can lead to substantial recovery costs,necessitating improvements in caisson stability to address the challenges posed by increased wave forces and changes in port logistics due to larger vessels.One approach to enhancing caisson stability is the use of long caissons.Long caisson is commonly used where a breakwater is needed to withstand wave action and distribute forces evenly along a length of breakwater.The construction of caissons faces challenges due to limitations on the size of individual units imposed by construction conditions,launching methods,and marine crane requirements.Therefore,connecting multiple caissons to form long caissons presents a viable alternative.This study suggested two connection methods for long caissons.The first method was a hemisphere caisson,which allows the connection parts to seat against each other under self-weight during construction.The second method was a displacement-allowing connection utilizing rubble(embedded rebar connection within riprap connection).This approach allows some displacement while employing rebar to resist excessive deformation,thereby dispersing the resulting wave forces to adjacent caissons.Performance comparisons between the developed connections and conventional gravity-type caissons were conducted using a finite element analysis model.The results indicate that the proposed connections demonstrate improved resistance to wave forces compared to traditional caissons without such connections.Further studies should include field applications and performance evaluations of various caisson sizes under different environmental and geological conditions.
基金Project(51275444) supported by the National Natural Science Foundation of ChinaProject(20121333110003) supported by the Specialized Research Fund for the Doctoral Program of Higher Education,China+1 种基金Project(E2014203271) supported by the Natural Science Foundation–Steel and Iron Foundation of Hebei ProvinceChina
文摘Based on the elastoplastic mechanical properties of the weld and heat affected zone metals obtained by a nanoindentation test, a theoretical calculation model was established for the forming limit diagram（FLD） of tailor-welded blanks（TWBs） on the basis of plastic constitutive relations and Hosford yield criteria. Hemispherical punch bulging tests were performed to verify the FLD theoretical calculation results. The results demonstrated that not only the FLD theoretical calculation of base materials but also that of TWBs had a good agreement with their experiments. Besides, poorer formability of TWBs caused its FLD significantly lower than that of base materials. The theoretical calculation model offers a reliable approach to obtain the specific FLD of TWBs.
基金the Hangzhou Science and Technology Bureau,No.20191203B84.
文摘BACKGROUND Wernicke's encephalopathy is a disease caused by thiamine deficiency.The lesions usually involve the periphery of the aqueduct,midbrain,tectum,third ventricle,papillary body,and thalamus.It is very rare to affect the vermis and cerebellar hemispheres.CASE SUMMARY We report a 77-year-old female patient admitted to the emergency department of our hospital for 2 d of unconsciousness.Brain magnetic resonance imaging showed increased diffusion weighted imaging signals in the bilateral thalamus,periventricular regions of the third ventricle,corpora quadrigemina,vermis,and cerebellar hemispheres.Wernicke's encephalopathy was considered.She was given thiamine therapy and became conscious after the treatment.CONCLUSION Wernicke's encephalopathy may have various imaging manifestations.Clinicians should keep in mind that Wernicke’s encephalopathy may occur in patients who experience prolonged periods of malnutrition.
文摘A scheme of hemispherical hot cavity solid ion source with electron impact is brought up. Sample evaporation and ionization is accomplished in the quasi-tight hemispherical cavity. The two axial designed holes are used to lead electrons into the cavity and to draw ions out of it. The area of two holes takes up only 1/150 of whole cavity's surface area. Sample atoms after evaporation will go through many times of sticking, desorption, release and finally diffuse out of the cavity and be partly ionized. The flying direction of atoms and ions in cavity points to the cavity center. Electrons from ring cathode are focused into the cavity by electrostatic field without magnet. The hemispherical cavity was heated by axis current which forms a centripetal field to drift ions in cavity. In the area close to the cavity center, ions will be drawn out and focused to a point. The atom's ionization efficiency, the ion's extracting performance, the fractionation and chemistry selectivity, and the applicable scope about this ion source are discussed.
文摘The enrichment by highly information load of the school educational process, which leads in severe environment to psycho-emotional stress, confirms the necessity of studying the psycho-emotional and physiological stability of the senior schoolboys to information educational stress in rugged climate/geographic regions of Siberia. Observed were the 110 teenagers, the inhabitants of Novosibirsk, the students of 9th-10th classes of the special lycée. Clinical, psychological, psychophysiological, biochemical and hormonal methods of observation were used. It was shown that efficiency of the modern information-enriched educational process defines a complex of individual adaptive characteristics of an organism, including lateral phenotype of the prevalence of cerebral hemispheres, the stability of psychophysiological response, minimization of painful reaction to sharp changes of the factors of nature—meteosensitivity, and also the belonging to chronotypes (morning or evening). These features form the basis of stability of the young organism to the educational information stress and to the action of rugged climate-meteorological and biorhytmological factors, aggravating this stress.
