Background:Intrinsic capacity reflects the overall health status of older adults and decline in intrinsic abilities can lead to adverse health outcomes.However,empirical studies examining the association between digit...Background:Intrinsic capacity reflects the overall health status of older adults and decline in intrinsic abilities can lead to adverse health outcomes.However,empirical studies examining the association between digital health literacy,health-promoting lifestyles and intrinsic capacity are scarce.Methods:A cross-sectional study was conducted.Using convenience sampling method,371 older adults were recruited from communities.Multidimensional intrinsic capacity,digital health literacy,health promoting lifestyle and sociodemographic information were measured.Results:The intrinsic capacity of older adults scored 3.75±1.10.The prevalences of declined cognitive capacity,psychological capacity,sensory capacity,vitality,and locomotor capacity were 13.7%,24.3%,19.1%,14.8%,53.1%,respectively.The multiple regression analysis revealed that age(β=−0.253),only living with children and/or grandchildren(β=0.249),current working status(β=−0.132),number of chronic diseases(β=−0.149),frequency of Internet usage(β=0.193),the domain of ability to acquire and evaluate digital health information(β=0.197)in digital health literacy,and the domain of nutrition(β=0.171)in health-promoting lifestyle were the significant factors influencing intrinsic capacity,explaining 27.1%of the variance.Conclusion:Digital health literacy and health-promoting lifestyle have a significant impact on intrinsic capacity.Enhancing digital health literacy and advocating a health-promoting lifestyle are critical to promoting intrinsic capacity for community-dwelling older adults.展开更多
Polygonati Rhizoma,a functional food and a traditional Chinese medicine broadly used in China and several Southeast Asia countries,possesses effective health-promoting activities.Prepared from 3 plants in Polygonatum ...Polygonati Rhizoma,a functional food and a traditional Chinese medicine broadly used in China and several Southeast Asia countries,possesses effective health-promoting activities.Prepared from 3 plants in Polygonatum genus(Polygonatum kingianum,Polygonatum sibiricum,and Polygonatum cyrtonema),Polygonati Rhizoma has drawn increasing attention due to its remarkable immune-enhancing and metabolic regulatory activities in recent years.In this review,we summarized the updated research of chemical constituents and biological activities of Polygonati Rhizoma,especially the metabolic regulation,immunomodulatory effects,and anti-fatigue activities,aiming to provide a comprehensive understanding,broaden the usage and promote more in-depth exploration of Polygonati Rhizoma as a functional food.展开更多
The purpose of this study was to determine health-promoting behaviours of university nursing students in Jordan. This descriptive cross-sectional study used convenient sampling technique to recruit 167 undergraduate n...The purpose of this study was to determine health-promoting behaviours of university nursing students in Jordan. This descriptive cross-sectional study used convenient sampling technique to recruit 167 undergraduate nursing students in Jordan. Data were collected by using an Arabic version of Health-Promoting Lifestyle Profile II. The study results revealed that the mean item score for total Health-Promoting Lifestyle Profile II was (127.24 ± 21.03). The students obtained highest scores in spiritual growth (25.04 ± 4.70) and lowest in physical activity subscales (16.27 ± 5.21). Significant difference was found between Health-Promoting Lifestyle Profile II subscales (stress management, health responsibility, and interpersonal relations) and students’ age and gender.展开更多
Objectives: To determine health promoting behaviors of university students in Jordan and factors influencing them. Design and Methods: A cross-sectional descriptive design was used to recruit convenience sample (n = 5...Objectives: To determine health promoting behaviors of university students in Jordan and factors influencing them. Design and Methods: A cross-sectional descriptive design was used to recruit convenience sample (n = 525) of university students receiving education from two governmental and one private universities in Jordan. Data were collected between September 2013 and January 2014 by using Health Promoting Lifestyle Profile II. Pender Model provided conceptual framework to guide the study. Results: The mean score of Health Promoting Lifestyle Profile of the student was at (127.87 ± 19.91). Significant differences were found between Health Promoting Lifestyle Profile mean score and the mean score of its subscales and student’s age, gender, employment status, family income, university type, and faculty type. Conclusions: These findings suggest that interventions are needed to enhance the practice of health promoting behaviours. These interventions should focus on demographic variations among university students.展开更多
Introduction: The aim of this study was to determine Health-Promoting Behaviors among type 2 diabetic mellitus patients. Patients and Methods: A cross-sectional study was conducted on 440 diabetic patients referred to...Introduction: The aim of this study was to determine Health-Promoting Behaviors among type 2 diabetic mellitus patients. Patients and Methods: A cross-sectional study was conducted on 440 diabetic patients referred to selected teaching hospitals affiliated to Tehran University of Medical Sciences (TUMS) during six months in 2013. A two section 40-items self-report Questionnaire with demographic variables (12 items) and Health-Promoting Behaviors scale (28 items) included exercise (7 items), risk reducing (7 items), life enjoyment (3 items), stress management (5 items), responsibility (3 items) and healthy eating (3 items) domains. Data was analyzed using SPSS software version 11.5. Level of significance was set at p 0.05 level. Results: Mean scores of total health promoting behaviors in participants were (55.88 ± 18.09) and in domains of exercise, risk reducing, life?enjoyment, stress management, responsibility and healthy eating were (8.2 ± 6.5), (12.2 ± 6.1), (7.8 ± 2.6), (12.3 ± 3.8), (3.3 ± 3.1) and (6.9 ± 2.8) respectively. Life enjoyment was emphasized as the most significant domain in health promoting behaviors scale (65 percent). Study results revealed that there was a significant association among total health promoting behavior and age (p = 0.01), occupation (p = 0.01), family income (p p = 0.01) and HbA1C(p < 0.001). Conclusion: Study findings revealed the necessity of tailoring specific intervention programs to promote exercise and responsibility domains posit.展开更多
Background: The increasing prevalence of type 2 diabetes mellitus (T2DM) poses a major public health challenge throughout the world. It is a major healthcare issue among the elderly. This study was to identify the ass...Background: The increasing prevalence of type 2 diabetes mellitus (T2DM) poses a major public health challenge throughout the world. It is a major healthcare issue among the elderly. This study was to identify the association between the health promoting behaviors and the diabetic control of type 2 diabetes mellitus (T2DM) patients. Methods: Cross sectional and descriptive research designs were used in this study. Participants were enrolled from three medical centers in northern, central and southern Taiwan during August, 2010 and June, 2011. The instruments encompassed biochemical indicators, and the preliminary developed scale of diabetes mellitus and health promotion (DMHP). Results: A total of 323 participants with T2DM were included in this study. The results showed 1) a high percentage of the participants used cigarette smoking, alcohol drinking and betel nut chewing, which were not conducive to adopting health promoting behaviors;2) a high percentage of patients showed abnormal blood glucose, dyslipidemia, and elevated blood pressure;3) few of the participants practiced ideally health promoting behaviors;and 4) practicing health-promoting behavior was positively associated with fasting blood glucose (FBG) and HbA1c levels. Conclusions: Patients with higher health promotion scores had better diabetic control. Less physical activity was found among those addicted to cigarette, alcohol and betel nut consumption. The findings suggest that health care providers should assess health promoting behaviors first for each diabetic patient.展开更多
Objective:The aim of this study was to evaluate health-promoting behaviors among hypertensive patients with and without comorbidities.Methods:A cross-sectional study using multistage cluster sampling in Indonesia was ...Objective:The aim of this study was to evaluate health-promoting behaviors among hypertensive patients with and without comorbidities.Methods:A cross-sectional study using multistage cluster sampling in Indonesia was applied.The health-promoting behaviors were assessed using Health-Promoting Lifestyle Profile 2 and analyzed using independent t-test,point-biserial correlation,and logistic regression.Results:A total of 116 participants joined this study.The score of health-promoting behaviors in adults with and without hypertension was 2.90 and 2.79,respectively.Hypertensive patients with comorbidities had significantly higher results than those without comorbidities,with the following results for the considered subscales:total score(t=-2.00,P=0.047);health responsibility(t=-3.46,P=0.001);and nutrition(t=-2.82,P=0.006).Positive correlations were found between health responsibility(r_(pb)=0.260,P<0.01),nutrition(r_(pb)=0.255,P<0.01),and health-promoting behaviors(r_(pb)=0.185,P<0.05)and the existing comorbidity.Only gender indicated a significant outcome for the existing comorbidity in hypertensive patients(odds ratio=4.314,P=0.027,95%confidence interval=1.185-15.706).Conclusions:Hypertensive patients with comorbidities showed higher engagement in health-promoting behaviors and the male gender was a significant predictor for existing comorbidity among patients with hypertension.展开更多
Studies have indicated that lack of regular physical exercise and not adhering to a health-promot- ing lifestyle among student nurses are barriers to their encouraging patients to exercise. On the other hand, nurses w...Studies have indicated that lack of regular physical exercise and not adhering to a health-promot- ing lifestyle among student nurses are barriers to their encouraging patients to exercise. On the other hand, nurses who personally embrace physical activity are more likely to encourage their patients to improve their health through physical activity or diet. As a result, promoting an active and healthy lifestyle among student nurses is important because this has a crucial role in their subsequently encouraging healthy lifestyles among their patients. The aims of this study were to determine the physical activity levels and health-promoting lifestyles among student nurses in Malaysia, and to investigate whether there was a correlation between the physical activity levels of student nurses and their lifestyle habits. Further investigation was also carried out to correlate lifestyle habits with physical activity during weekdays and at the weekends. This study involved 189 student nurses who were pursuing Diplomas and Bachelor Degrees in local government universities. The Yamax Digi-Walker pedometer was used to measure physical activity, while the Health-Promoting Lifestyle Profile (HPLP) II questionnaire was used to assess the health-pro- moting lifestyles of the participants. The HPLP II consisted of six sub-scales which included health responsibility, physical activity, nutrition, spiritual growth, interpersonal relations, and stress management. According to the results on physical activity, the student nurses had a mean of 8275.97 ± 2210.174 steps per day and were thus categorised as somewhat active. Additionally, the student nurses were found to be more active during weekends (M = 8389.75, SD = 2689.12) as compared to weekdays (M = 8230.46, SD = 2353.97). According to previous studies, both step counts are classified in the “somewhat active” category. Overall, the results for HPLP II showed that student nurses students in Malaysia had a positive health-promoting lifestyle with a score of 2.58 ± 0.34 on a 4-point Likert scale. The highest score was reported in spiritual growth, with a score of 2.92 ± 0.43. Meanwhile, physical activity was observed to be the lowest, with a score of 1.74 ± 0.39. The results found no correlation between physical activity and overall health-promoting lifestyle among student nurses in Malaysia (r = 0.06, n = 189, p < 0.37). However, there was a significant relationship between physical activity (measured by the pedometer) and physical activity habit (measured through the questionnaire) among the student nurses (r = 0.24, n = 189, p < 0.01). According to the findings, when the participants indicated in the questionnaire that they were active physically, the pedometer readings also showed a corresponding similarity in terms of their daily physical activities.展开更多
Background:In this study,we aimed to validate and test the reliability of the Yonsei lifestyle profile(YLP)in assessing multifaceted health lifestyle levels in a study population from the United States.Methods:The YLP...Background:In this study,we aimed to validate and test the reliability of the Yonsei lifestyle profile(YLP)in assessing multifaceted health lifestyle levels in a study population from the United States.Methods:The YLP-English version and health-promoting lifestyle profile II were administered to 100 individuals living in the United States.Concurrent validity was analyzed using Pearson's correlation coefficient,and discriminant validity was examined by comparing sex and age differences through t-tests and multiple variance analysis.Internal consistency was assessed using Cronbach'sαfor each sub-factor.Results:The YLP-English Version demonstrated concurrent validity with the Health-Promoting Lifestyle Profile II,showing consistent correlations for the total score(0.3,p<0.01)and frequency sub-factors(0.25-0.69,p<0.01).Among the satisfaction sub-factors,only nutrition showed a weak negative correlation(-0.19,p<0.01);all others were nonsignificant.Discriminant validity revealed no significant sex differences,but physical activity frequency varied across age groups.Internal consistency was high(Cronbach'sα=0.80-0.86).Conclusion:In this study,we validated the YLP-English version as a reliable instrument for assessing health-related lifestyle behaviors.The YLP uniquely captures both lifestyle frequency and satisfaction,offering a comprehensive perspective on health behaviors.Although this tool is currently most applicable in population-level studies,future research should establish clinical thresholds to enhance its utility in individualized health assessments and interventions.展开更多
Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12...Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12-80 years.The qi stagnation constitution was assessed using the Constitution in Chinese Medicine Questionnaire.Health status was evaluated through medical records and the Subhealth Measurement Scale V1.0(SHMS V1.0).Health-promoting lifestyles were measured using the Health-Promoting Lifestyle Profile Ⅱ(HPLP-Ⅱ).Results:Of the 24159 participants,16.1%and 15.2%were classified as“always”and“sometimes”having the qi stagnation constitution,respectively.Those classified as“rarely”having the qi stagnation constitution scored higher on both the HPLP-Ⅱ and SHMS V1.0.The participants classified as“always”having the qi stagnation constitution showed a significant association with SHS or disease compared to other imbalanced constitutions.Those in the“always”category were approximately 21 times more likely to be classified as having SHS(odds ratio[OR]:21.17,95%confidence interval[CI]:15.74-28.45),whereas those in the“sometimes”category were approximately six times more likely(OR:5.89,95%CI:5.04-6.90).Accordingly,the qi stagnation constitution score was significantly associated with the diagnosis of SHS,with an area under the curve of 0.77(P<.001).A score of 18.75 yielded the highest Youden Index(0.407),with a sensitivity of 60.5%and a specificity of 80.3%.Significant associations were observed between health-promoting lifestyles and qi stagnation constitution severity in an ordinal regression analysis(P<.001).Protective factors included stress management(OR:1.59),self-actualization(OR:1.57),and exercise(OR:1.36).In contrast,poorer interpersonal relationships(OR:0.79),greater health responsibilities(OR:0.86),and poorer nutrition(OR:0.91)were associated with increased severity.Conclusion:Modulating the qi stagnation constitution through lifestyle interventions may help prevent the progression of SHS to disease,which aligns with core preventive principles in traditional Chinese medicine.展开更多
To evaluate the supplementary blue light intensity on growth and health-promoting compounds in pak choi（Brassica campestris ssp.chinensis var.communis）,four blue light intensity treatments（T0,T50,T100 and T150 indi...To evaluate the supplementary blue light intensity on growth and health-promoting compounds in pak choi（Brassica campestris ssp.chinensis var.communis）,four blue light intensity treatments（T0,T50,T100 and T150 indicate 0,50,100,and 150μmol m^（-2） s^（-1）,respectively）were applied 10 days before harvest under greenhouse conditions.Both of cultivars（greenand red-leaf pak choi）under T50 had the highest yield,content of chlorophyll and sugars.With light intensity increasing,antioxidant compounds（vitamin C and carotenoids）significantly increased,while nitrate content showed an opposite trend.The health-promoting compounds（phenolics,flavonoids,anthocyanins,and glucosinolates）were significantly higher under supplementary light treatment than T0,so as the antioxidant capacity（2,2-diphenyl-1-picrylhydrazyl and ferric-reducing antioxidant power）.The species-specific differences in photosynthetic pigment and health-promoting compounds was found in green-and red-leaf pak choi.T50 treatment could be used for yield improvement,whereas T100 treatment could be applied for quality improvement.Results showed that blue light intensity can regulate the accumulation of biomass,morphology and health-promoting compounds in pak choi under greenhouse conditions.展开更多
Tai Chi,a traditional Chinese martial art and health exercise,has gained significant global attention and recognition.The clinical benefits of Tai Chi have been studied extensively in recent decades.We conducted a sys...Tai Chi,a traditional Chinese martial art and health exercise,has gained significant global attention and recognition.The clinical benefits of Tai Chi have been studied extensively in recent decades.We conducted a systematic search of PubMed,Web of Science,EMBASE databases,and the China National Knowledge Infrastructure,identifying and reviewing 241 clinical trials on the benefits of Tai Chi from their inception to June 1,2023.Most of these studies have consistently demonstrated the positive impact of Tai Chi on balance,cognitive function,mood regulation,sleep quality,pain relief,cardiorespiratory function,and overall health.In the future,the key to fostering the ongoing development of this field lies in comprehensive research on standardized study designs and reporting,the scope of Tai Chi applications,and the core factors influencing its efficacy.展开更多
Objectives: This descriptive study of 219 undergraduate medical students at Patan Academy of Health Sciences in Nepal was conducted to evaluate the relationships of their demographic variables with a health-promoting ...Objectives: This descriptive study of 219 undergraduate medical students at Patan Academy of Health Sciences in Nepal was conducted to evaluate the relationships of their demographic variables with a health-promoting lifestyle profile. Methods: The Health Promoting Lifestyle Profile (HPLP) questionnaire was used to study students’ lifestyles. We compared the HPLP scores according to gender, residence type, school background and year of study. One-way analysis of variance (ANOVA) and multiple comparison test were conducted to identify significant differences among university year (first, second, third and fourth) groups. Multiple regression analysis was used to analyze the effects of various demographics on the overall HPLP score and the six health-promoting lifestyle subscales. Results: The overall HPLP mean score of participants was 2.60 ± 0.29, with the highest mean scores being for spiritual growth (2.99 ± 0.42) and interpersonal relations (2.90 ± 0.35), and the lowest mean scores being for health responsibility (2.39 ± 0.39) and physical activity (2.25 ± 0.54), respectively. The overall HPLP score of the students was the highest for the first year students at 2.65 ± 0.26. The male students had a better overall HPLP score, although female students obtained better score in some subscales such as health responsibility, interpersonal relations and nutrition. The students from a public school background had significantly higher scores for health responsibility, physical activity and stress management than those who graduated school level education from a private school. Conclusions: The results of this study reveal that the status of health promoting behaviors among the students was acceptable with ample room for improvement. Implementation of health education and promotion programs with an emphasis on the different dimensions of health lifestyle behaviors is recommended.展开更多
The study is to explore the well-being of nurses in Eastern Taiwan,China and significant predictive factors.Clinical nurses are responsible for improving patient well-being;whereas nurse's perceived well-being and...The study is to explore the well-being of nurses in Eastern Taiwan,China and significant predictive factors.Clinical nurses are responsible for improving patient well-being;whereas nurse's perceived well-being and which factors affect the well-being of nurses has not explored.A cross-sectional related survey is on nurses at a teaching hospital in Eastern Taiwan,China.There were 375 nurses completed surveys.The instruments include Well-Being Scale,Work Environment Perception Scale,Health-Promoting Lifestyle Scale and Leisure Coping Strategy Scale.Data were analyzed using descriptive statistic,Spearman's correlation and stepwise regression.Joy and comfort were two major components of nurses'well-being;seven significant predictors explained 63.9%of the variance in the well-being distribution.The findings supported ways to promote the nurses'well-being with the seven significant predictors.These results from the clinical nurses'perspective and provide an evidence for policy development,improve nurses work environment and to promote nurse healthy life and well-being.展开更多
Wild species of the subgenus Amygdalus(genus Prunus and family Rosaceae)have been insufficiently studied with regard to their chemical components and their pharmacological potential.The present study aimed at the inve...Wild species of the subgenus Amygdalus(genus Prunus and family Rosaceae)have been insufficiently studied with regard to their chemical components and their pharmacological potential.The present study aimed at the investigation of the chemical composition of leaves and twigs of A.orientalis Mill.and A.zielinskii Browicz,thus assessing the antioxidant and enzyme inhibiting potential,as well as to define the safety profile.Our results showed that extracts were rich in phenolics,and liquid chromatography-diode array detector-tandem mass spectrometry(LC-DAD-MS)analysis allowed the identification of phenolic acids,flavonoids,coumarins,proanthocyanins,amino acids,fatty acids and derivatives.The assessment of the antioxidant potential demon-strated that the ethyl acetate extract of A.zielinskii twigs recorded the highest anti-ABTS(2,2′-Azino-bis(3-eth-ylbenzothiazoline-6-sulfonic acid))(1298.10 mg trolox equivalent(TE)/g),total antioxidant(4.98 mmol TE/g),Cu^(++)(1211.47 mg TE/g)and Fe^(+++)(907.86 mg TE/g)reducing properties.In addition,it also had the highest anti-DPPH(2,2-diphenyl-1-picrylhydrazyl)activity(560.17 mg TE/g),together with its methanolic extract and that of A.orientalis twigs,whereas the best chelation power was exerted by the ethyl acetate extract of A.orientalis leaves(31.10 mg EDTAE/g).Regarding enzyme inhibition,methanolic extracts of the leaves and twigs of both species displayed the highestα-glucosidase and tyrosinase inhibitory activity,while ethyl acetate extracts of A.orientalis twigs and leaves revealed the best butyrylcholinesterase(2.35 mg galantamine equivalent(GALAE)/g)inhibitory activity.Docking studies demonstrated strong binding affinities of compounds like rutin,kaempferol derivatives,and isorhamnetin-3-O-rutinoside with the abovementioned enzymes,supporting the consistent inhibitory potential.Moreover,we investigated the potential cytotoxicity of these extracts in different human cell lines,thus proving their safety.These results highlight the potential of the two Amygdalus species as a new source of bioactive molecules for the development of health-promoting applications.展开更多
The growing availability of horticultural by-products presents an opportunity for their sustainable use as sources of bioactive compounds with potential health benefits.In this study,the phytochemical composition(incl...The growing availability of horticultural by-products presents an opportunity for their sustainable use as sources of bioactive compounds with potential health benefits.In this study,the phytochemical composition(including polyphenols,terpenoids,and sulfur-containing compounds)and in vitro biological activities of 9 by-products from citrus,pomegranate,broccoli,tomato,and carrot were quantitatively assessed.Pomegranate peels-particularly from the’Wonderful’cultivar-showed the highest antioxidant capacity(ABTS^(+):1297.2 mmol Trolox/kg dw)and strongest inhibitory activity againstα-glucosidase(IC_(50):0.1 mg/mL),α-amylase(17.3 mg/mL),and pancreatic lipase(0.3 mg/mL),associated with high levels of punicalagins and ellagic acid derivatives.Broccoli by-products,notably florets and leaves,were richer in sulforaphane and glucosinolates and showed relevant inhibitory effects on acetylcholinesterase(AChE)and butyrylcholinesterase(BuChE),with IC_(50)values as low as 103.3 mg/mL and 54.1 mg/mL,respectively.Pearson correlation and regression analyses revealed enzyme-specific phytochemical signatures:α-glucosidase inhibition was strongly associated with punicalagins and ellagic acid(r>0.95),lipase inhibition with total polyphenols,and cholinesterase inhibition with sulforaphane and glucosinolates.These findings demonstrate the functional potential of selected horticultural byproducts for targeted nutraceutical applications,particularly in the prevention of metabolic and neurodegenerative disorders.展开更多
Coconut oil(CO)has recently gained increasing scientific and industrial attention owing to its rich profile of medium-chain fatty acids(MCFAs)and diverse bioactive constituents.These unique components confer promising...Coconut oil(CO)has recently gained increasing scientific and industrial attention owing to its rich profile of medium-chain fatty acids(MCFAs)and diverse bioactive constituents.These unique components confer promising nutraceutical and functional properties relevant to both human health and sustainable livestock production.This review aims to provide an updated and integrative overview of the biological roles and mechanisms of coconut oil,emphasizing its potential applications in animal nutrition and health promotion.Coconut oil exhibits a wide spectrum of biological activities,including antimicrobial,antioxidant,anti-inflammatory,hepatoprotective,neuroprotective,and metabolic regulatory effects.These functions are primarily mediated through modulation of oxidative stress,lipid metabolism,and inflammatory signaling pathways.In animal production,dietary inclusion of coconut oil has been shown to improve growth performance,immune responses,and product quality,although some findings remain inconsistent and context dependent.Despite the increasing interest in its health benefits,clinical validation of coconut oil's long-term effects in humans and animals remains limited.Therefore,understanding its mechanisms of action and standardizing dosages are crucial to ensure safe and effective utilization.In summary,coconut oil represents a promising natural ingredient that bridges human nutrition and sustainable livestock production.However,further mechanistic and clinical investigations are warranted to substantiate its long-term functional and health-promoting effects.展开更多
Camels,particularly dromedaries,are vital to arid and semi-arid regions like Northeast Africa and Asia,where they thrive and provide essential nutrition.Camel milk is rich in essential vitamins(A,B,C,E),minerals(iron,...Camels,particularly dromedaries,are vital to arid and semi-arid regions like Northeast Africa and Asia,where they thrive and provide essential nutrition.Camel milk is rich in essential vitamins(A,B,C,E),minerals(iron,zinc,magnesium),and bioactive compounds,making it a valuable dietary source in resource-limited environments.Camel milk contains protective proteins such as lactoferrin,immunoglobulins,and lactoperoxidases,and these proteins generate bioactive peptides upon digestion that exhibit auspicious antidiabetic,anticancer,antihypertensive,antioxidant,antimicrobial,and hypocholesterolemic activities.While,low cholesterol and sugar levels in camel milk,combined with its insulin-like and anti-inflammatory properties,confer the potential therapeutic attributes against some conditions such as diabetes,autism,and autoimmune diseases.These unique properties of camel milk especially camel milk proteins have significant potential in food applications while a few of its industrial applications in food products like cheese,ice cream,milk powders and ice cream have also been discussed.This review is aimed to comprehensively review camel milk by going through its particular composition,nutritional and bioactive profile,associated health benefits,and industrial applications.展开更多
Grifola frondosa is a highly valuable edible and medicinal fungus with significant health benefits.In traditional Chinese medicine,has been extensively utilized for its therapeutic properties,playing a vital role in t...Grifola frondosa is a highly valuable edible and medicinal fungus with significant health benefits.In traditional Chinese medicine,has been extensively utilized for its therapeutic properties,playing a vital role in treating various diseases related to immune modulation and inflammation.Polysaccharides are the main active com-pound in G.frondosa,and their biological activities are closely related to their composition.The Grifola frondosa polysaccharides(GFPs)interact with key immune receptors such as Toll-like receptors and Dectin-1,which activate macrophages,natural killer cells,and dendritic cells.This interaction enhances the immune system’s capacity to mount effective responses against infections and malignancies.These polysaccharides control glucose metabolism and regulate insulin sensitivity,indicating their potential for managing and preventing metabolic disorders like diabetes.Although the preclinical studies are promising,further research is essential to standardize extraction techniques,conform clinical efficacy,and clarify the mechanism of health benefits.This review provides a comprehensive overview of recent advances in the production,properties,structural characteristics,and biological activities of GFPs.It highlights their therapeutic potential and promotes further research to support their development and application in functional foods,nutraceuticals,and pharmaceutical formulation.展开更多
In the context of a global public health crisis,such as COVID-19,developing interventions to improve population health behav-iors has emerged as a pivotal element of health management strategies.The efficacy of variou...In the context of a global public health crisis,such as COVID-19,developing interventions to improve population health behav-iors has emerged as a pivotal element of health management strategies.The efficacy of various interventions implemented during this period has varied,and the impact of different variables on these intervention outcomes remains to be fully elucidated.This study screened 57 papers(n=47,264)by searching electronic databases and revealed the optimal intervention through pairwise meta-analysis and network meta-analysis,as well as the changes in intervention effectiveness under different conditions.Our research findings indicate that interventions for preventive health behaviors and health-promoting behaviors have significant effects.For preventive health behaviors,the intervention method of health education and low-risk information framework under information intervention was the optimal intervention.For health-promoting behaviors,the exercise intervention and the prosocial information framework with information intervention were the optimal interventions.Accordingly,future research should focus on the in-depth exploration of specific interventions to establish and improve the effectiveness of interventions.展开更多
基金funded by the College Students’Innovation and Entrepreneurship Program(X2024110650385).
文摘Background:Intrinsic capacity reflects the overall health status of older adults and decline in intrinsic abilities can lead to adverse health outcomes.However,empirical studies examining the association between digital health literacy,health-promoting lifestyles and intrinsic capacity are scarce.Methods:A cross-sectional study was conducted.Using convenience sampling method,371 older adults were recruited from communities.Multidimensional intrinsic capacity,digital health literacy,health promoting lifestyle and sociodemographic information were measured.Results:The intrinsic capacity of older adults scored 3.75±1.10.The prevalences of declined cognitive capacity,psychological capacity,sensory capacity,vitality,and locomotor capacity were 13.7%,24.3%,19.1%,14.8%,53.1%,respectively.The multiple regression analysis revealed that age(β=−0.253),only living with children and/or grandchildren(β=0.249),current working status(β=−0.132),number of chronic diseases(β=−0.149),frequency of Internet usage(β=0.193),the domain of ability to acquire and evaluate digital health information(β=0.197)in digital health literacy,and the domain of nutrition(β=0.171)in health-promoting lifestyle were the significant factors influencing intrinsic capacity,explaining 27.1%of the variance.Conclusion:Digital health literacy and health-promoting lifestyle have a significant impact on intrinsic capacity.Enhancing digital health literacy and advocating a health-promoting lifestyle are critical to promoting intrinsic capacity for community-dwelling older adults.
基金funded by Scientific and Technological Research Project and Technology Innovation Platform Project of Huibei Provincial Department of Science and Technology(2025AFD345 and 2024CSA071)grant from Huanggang Science and Technology Bureau(ZDZX20240008)。
文摘Polygonati Rhizoma,a functional food and a traditional Chinese medicine broadly used in China and several Southeast Asia countries,possesses effective health-promoting activities.Prepared from 3 plants in Polygonatum genus(Polygonatum kingianum,Polygonatum sibiricum,and Polygonatum cyrtonema),Polygonati Rhizoma has drawn increasing attention due to its remarkable immune-enhancing and metabolic regulatory activities in recent years.In this review,we summarized the updated research of chemical constituents and biological activities of Polygonati Rhizoma,especially the metabolic regulation,immunomodulatory effects,and anti-fatigue activities,aiming to provide a comprehensive understanding,broaden the usage and promote more in-depth exploration of Polygonati Rhizoma as a functional food.
文摘The purpose of this study was to determine health-promoting behaviours of university nursing students in Jordan. This descriptive cross-sectional study used convenient sampling technique to recruit 167 undergraduate nursing students in Jordan. Data were collected by using an Arabic version of Health-Promoting Lifestyle Profile II. The study results revealed that the mean item score for total Health-Promoting Lifestyle Profile II was (127.24 ± 21.03). The students obtained highest scores in spiritual growth (25.04 ± 4.70) and lowest in physical activity subscales (16.27 ± 5.21). Significant difference was found between Health-Promoting Lifestyle Profile II subscales (stress management, health responsibility, and interpersonal relations) and students’ age and gender.
文摘Objectives: To determine health promoting behaviors of university students in Jordan and factors influencing them. Design and Methods: A cross-sectional descriptive design was used to recruit convenience sample (n = 525) of university students receiving education from two governmental and one private universities in Jordan. Data were collected between September 2013 and January 2014 by using Health Promoting Lifestyle Profile II. Pender Model provided conceptual framework to guide the study. Results: The mean score of Health Promoting Lifestyle Profile of the student was at (127.87 ± 19.91). Significant differences were found between Health Promoting Lifestyle Profile mean score and the mean score of its subscales and student’s age, gender, employment status, family income, university type, and faculty type. Conclusions: These findings suggest that interventions are needed to enhance the practice of health promoting behaviours. These interventions should focus on demographic variations among university students.
文摘Introduction: The aim of this study was to determine Health-Promoting Behaviors among type 2 diabetic mellitus patients. Patients and Methods: A cross-sectional study was conducted on 440 diabetic patients referred to selected teaching hospitals affiliated to Tehran University of Medical Sciences (TUMS) during six months in 2013. A two section 40-items self-report Questionnaire with demographic variables (12 items) and Health-Promoting Behaviors scale (28 items) included exercise (7 items), risk reducing (7 items), life enjoyment (3 items), stress management (5 items), responsibility (3 items) and healthy eating (3 items) domains. Data was analyzed using SPSS software version 11.5. Level of significance was set at p 0.05 level. Results: Mean scores of total health promoting behaviors in participants were (55.88 ± 18.09) and in domains of exercise, risk reducing, life?enjoyment, stress management, responsibility and healthy eating were (8.2 ± 6.5), (12.2 ± 6.1), (7.8 ± 2.6), (12.3 ± 3.8), (3.3 ± 3.1) and (6.9 ± 2.8) respectively. Life enjoyment was emphasized as the most significant domain in health promoting behaviors scale (65 percent). Study results revealed that there was a significant association among total health promoting behavior and age (p = 0.01), occupation (p = 0.01), family income (p p = 0.01) and HbA1C(p < 0.001). Conclusion: Study findings revealed the necessity of tailoring specific intervention programs to promote exercise and responsibility domains posit.
文摘Background: The increasing prevalence of type 2 diabetes mellitus (T2DM) poses a major public health challenge throughout the world. It is a major healthcare issue among the elderly. This study was to identify the association between the health promoting behaviors and the diabetic control of type 2 diabetes mellitus (T2DM) patients. Methods: Cross sectional and descriptive research designs were used in this study. Participants were enrolled from three medical centers in northern, central and southern Taiwan during August, 2010 and June, 2011. The instruments encompassed biochemical indicators, and the preliminary developed scale of diabetes mellitus and health promotion (DMHP). Results: A total of 323 participants with T2DM were included in this study. The results showed 1) a high percentage of the participants used cigarette smoking, alcohol drinking and betel nut chewing, which were not conducive to adopting health promoting behaviors;2) a high percentage of patients showed abnormal blood glucose, dyslipidemia, and elevated blood pressure;3) few of the participants practiced ideally health promoting behaviors;and 4) practicing health-promoting behavior was positively associated with fasting blood glucose (FBG) and HbA1c levels. Conclusions: Patients with higher health promotion scores had better diabetic control. Less physical activity was found among those addicted to cigarette, alcohol and betel nut consumption. The findings suggest that health care providers should assess health promoting behaviors first for each diabetic patient.
基金supported under the project “Health promoting behaviors among patients with cardiovascular diseases”(No. 20170032)
文摘Objective:The aim of this study was to evaluate health-promoting behaviors among hypertensive patients with and without comorbidities.Methods:A cross-sectional study using multistage cluster sampling in Indonesia was applied.The health-promoting behaviors were assessed using Health-Promoting Lifestyle Profile 2 and analyzed using independent t-test,point-biserial correlation,and logistic regression.Results:A total of 116 participants joined this study.The score of health-promoting behaviors in adults with and without hypertension was 2.90 and 2.79,respectively.Hypertensive patients with comorbidities had significantly higher results than those without comorbidities,with the following results for the considered subscales:total score(t=-2.00,P=0.047);health responsibility(t=-3.46,P=0.001);and nutrition(t=-2.82,P=0.006).Positive correlations were found between health responsibility(r_(pb)=0.260,P<0.01),nutrition(r_(pb)=0.255,P<0.01),and health-promoting behaviors(r_(pb)=0.185,P<0.05)and the existing comorbidity.Only gender indicated a significant outcome for the existing comorbidity in hypertensive patients(odds ratio=4.314,P=0.027,95%confidence interval=1.185-15.706).Conclusions:Hypertensive patients with comorbidities showed higher engagement in health-promoting behaviors and the male gender was a significant predictor for existing comorbidity among patients with hypertension.
文摘Studies have indicated that lack of regular physical exercise and not adhering to a health-promot- ing lifestyle among student nurses are barriers to their encouraging patients to exercise. On the other hand, nurses who personally embrace physical activity are more likely to encourage their patients to improve their health through physical activity or diet. As a result, promoting an active and healthy lifestyle among student nurses is important because this has a crucial role in their subsequently encouraging healthy lifestyles among their patients. The aims of this study were to determine the physical activity levels and health-promoting lifestyles among student nurses in Malaysia, and to investigate whether there was a correlation between the physical activity levels of student nurses and their lifestyle habits. Further investigation was also carried out to correlate lifestyle habits with physical activity during weekdays and at the weekends. This study involved 189 student nurses who were pursuing Diplomas and Bachelor Degrees in local government universities. The Yamax Digi-Walker pedometer was used to measure physical activity, while the Health-Promoting Lifestyle Profile (HPLP) II questionnaire was used to assess the health-pro- moting lifestyles of the participants. The HPLP II consisted of six sub-scales which included health responsibility, physical activity, nutrition, spiritual growth, interpersonal relations, and stress management. According to the results on physical activity, the student nurses had a mean of 8275.97 ± 2210.174 steps per day and were thus categorised as somewhat active. Additionally, the student nurses were found to be more active during weekends (M = 8389.75, SD = 2689.12) as compared to weekdays (M = 8230.46, SD = 2353.97). According to previous studies, both step counts are classified in the “somewhat active” category. Overall, the results for HPLP II showed that student nurses students in Malaysia had a positive health-promoting lifestyle with a score of 2.58 ± 0.34 on a 4-point Likert scale. The highest score was reported in spiritual growth, with a score of 2.92 ± 0.43. Meanwhile, physical activity was observed to be the lowest, with a score of 1.74 ± 0.39. The results found no correlation between physical activity and overall health-promoting lifestyle among student nurses in Malaysia (r = 0.06, n = 189, p < 0.37). However, there was a significant relationship between physical activity (measured by the pedometer) and physical activity habit (measured through the questionnaire) among the student nurses (r = 0.24, n = 189, p < 0.01). According to the findings, when the participants indicated in the questionnaire that they were active physically, the pedometer readings also showed a corresponding similarity in terms of their daily physical activities.
基金supported by the Ministry of Education of the Republic of Korea and the National Research Foundation of Republic of Korea(NRF-2021S1A3A2A02096338).
文摘Background:In this study,we aimed to validate and test the reliability of the Yonsei lifestyle profile(YLP)in assessing multifaceted health lifestyle levels in a study population from the United States.Methods:The YLP-English version and health-promoting lifestyle profile II were administered to 100 individuals living in the United States.Concurrent validity was analyzed using Pearson's correlation coefficient,and discriminant validity was examined by comparing sex and age differences through t-tests and multiple variance analysis.Internal consistency was assessed using Cronbach'sαfor each sub-factor.Results:The YLP-English Version demonstrated concurrent validity with the Health-Promoting Lifestyle Profile II,showing consistent correlations for the total score(0.3,p<0.01)and frequency sub-factors(0.25-0.69,p<0.01).Among the satisfaction sub-factors,only nutrition showed a weak negative correlation(-0.19,p<0.01);all others were nonsignificant.Discriminant validity revealed no significant sex differences,but physical activity frequency varied across age groups.Internal consistency was high(Cronbach'sα=0.80-0.86).Conclusion:In this study,we validated the YLP-English version as a reliable instrument for assessing health-related lifestyle behaviors.The YLP uniquely captures both lifestyle frequency and satisfaction,offering a comprehensive perspective on health behaviors.Although this tool is currently most applicable in population-level studies,future research should establish clinical thresholds to enhance its utility in individualized health assessments and interventions.
基金supported by the National Natural Science Foundation of China(T2341019)NSFC-Guangdong Joint Fund(U1132001)+9 种基金General Program of the National Natural Science Foundation of China(82174243 and 82204948)Natural Science Foundation of Guangdong Province,China(2023A1515110757)Guangzhou Science and Technology Plan Project(2024B03J1343)Major Scientific and Technological Project of Guangzhou Municipal Health Commission(20252D003)Research Project of Traditional Chinese Medicine Bureau of Guangdong Province(20241208)General project of Beijing Natural Science Foundation(7242227)Fundamental Research Funds for the Central Universities(BZY-JMZY-2022-001 and 2023-JYB-JBZD-009)High-level Key Discipline of the National Administration of Traditional Chinese Medicine-Traditional Chinese Constitutional Medicine(zyyzdxk-2023251)Major Science and Technology Special Projects in Hubei Province(2023BCA005)the Chief Scientist Research Project of Hubei Shizhen Laboratory(HSL2024SX0002).
文摘Objective:To study the relationship between qi stagnation constitution and suboptimal health status(SHS)or lifestyle.Methods:From 2012 to 2013,we conducted a cross-sectional survey of 24159 Chinese individuals aged 12-80 years.The qi stagnation constitution was assessed using the Constitution in Chinese Medicine Questionnaire.Health status was evaluated through medical records and the Subhealth Measurement Scale V1.0(SHMS V1.0).Health-promoting lifestyles were measured using the Health-Promoting Lifestyle Profile Ⅱ(HPLP-Ⅱ).Results:Of the 24159 participants,16.1%and 15.2%were classified as“always”and“sometimes”having the qi stagnation constitution,respectively.Those classified as“rarely”having the qi stagnation constitution scored higher on both the HPLP-Ⅱ and SHMS V1.0.The participants classified as“always”having the qi stagnation constitution showed a significant association with SHS or disease compared to other imbalanced constitutions.Those in the“always”category were approximately 21 times more likely to be classified as having SHS(odds ratio[OR]:21.17,95%confidence interval[CI]:15.74-28.45),whereas those in the“sometimes”category were approximately six times more likely(OR:5.89,95%CI:5.04-6.90).Accordingly,the qi stagnation constitution score was significantly associated with the diagnosis of SHS,with an area under the curve of 0.77(P<.001).A score of 18.75 yielded the highest Youden Index(0.407),with a sensitivity of 60.5%and a specificity of 80.3%.Significant associations were observed between health-promoting lifestyles and qi stagnation constitution severity in an ordinal regression analysis(P<.001).Protective factors included stress management(OR:1.59),self-actualization(OR:1.57),and exercise(OR:1.36).In contrast,poorer interpersonal relationships(OR:0.79),greater health responsibilities(OR:0.86),and poorer nutrition(OR:0.91)were associated with increased severity.Conclusion:Modulating the qi stagnation constitution through lifestyle interventions may help prevent the progression of SHS to disease,which aligns with core preventive principles in traditional Chinese medicine.
基金supported by the National Key Research and Development Program of China (2017YFD0701500)the Teamwork Projects Funded by Guangdong Natural Science Foundation, China (S2013030012842)+1 种基金the Guangdong Provincial Science & Technology Project, China (2015A020209146, 2015B090903074)the Guangzhou Science & Technology Project, China (201605030005, 201704020058)
文摘To evaluate the supplementary blue light intensity on growth and health-promoting compounds in pak choi（Brassica campestris ssp.chinensis var.communis）,four blue light intensity treatments（T0,T50,T100 and T150 indicate 0,50,100,and 150μmol m^（-2） s^（-1）,respectively）were applied 10 days before harvest under greenhouse conditions.Both of cultivars（greenand red-leaf pak choi）under T50 had the highest yield,content of chlorophyll and sugars.With light intensity increasing,antioxidant compounds（vitamin C and carotenoids）significantly increased,while nitrate content showed an opposite trend.The health-promoting compounds（phenolics,flavonoids,anthocyanins,and glucosinolates）were significantly higher under supplementary light treatment than T0,so as the antioxidant capacity（2,2-diphenyl-1-picrylhydrazyl and ferric-reducing antioxidant power）.The species-specific differences in photosynthetic pigment and health-promoting compounds was found in green-and red-leaf pak choi.T50 treatment could be used for yield improvement,whereas T100 treatment could be applied for quality improvement.Results showed that blue light intensity can regulate the accumulation of biomass,morphology and health-promoting compounds in pak choi under greenhouse conditions.
基金The National Natural Science Foundation of China(82474657,82305362,82305360)the Sichuan Philosophy and Social Science Foundation(SCJJ24ZD101)+1 种基金the Science popularization project of Sichuan Science and Technology Department(2024JDKP0051)the Xinglin Promotion Program of Chengdu University of Traditional Chinese Medicine(QJJJ2022019,MPRC2022022,KPZX2022022).
文摘Tai Chi,a traditional Chinese martial art and health exercise,has gained significant global attention and recognition.The clinical benefits of Tai Chi have been studied extensively in recent decades.We conducted a systematic search of PubMed,Web of Science,EMBASE databases,and the China National Knowledge Infrastructure,identifying and reviewing 241 clinical trials on the benefits of Tai Chi from their inception to June 1,2023.Most of these studies have consistently demonstrated the positive impact of Tai Chi on balance,cognitive function,mood regulation,sleep quality,pain relief,cardiorespiratory function,and overall health.In the future,the key to fostering the ongoing development of this field lies in comprehensive research on standardized study designs and reporting,the scope of Tai Chi applications,and the core factors influencing its efficacy.
文摘Objectives: This descriptive study of 219 undergraduate medical students at Patan Academy of Health Sciences in Nepal was conducted to evaluate the relationships of their demographic variables with a health-promoting lifestyle profile. Methods: The Health Promoting Lifestyle Profile (HPLP) questionnaire was used to study students’ lifestyles. We compared the HPLP scores according to gender, residence type, school background and year of study. One-way analysis of variance (ANOVA) and multiple comparison test were conducted to identify significant differences among university year (first, second, third and fourth) groups. Multiple regression analysis was used to analyze the effects of various demographics on the overall HPLP score and the six health-promoting lifestyle subscales. Results: The overall HPLP mean score of participants was 2.60 ± 0.29, with the highest mean scores being for spiritual growth (2.99 ± 0.42) and interpersonal relations (2.90 ± 0.35), and the lowest mean scores being for health responsibility (2.39 ± 0.39) and physical activity (2.25 ± 0.54), respectively. The overall HPLP score of the students was the highest for the first year students at 2.65 ± 0.26. The male students had a better overall HPLP score, although female students obtained better score in some subscales such as health responsibility, interpersonal relations and nutrition. The students from a public school background had significantly higher scores for health responsibility, physical activity and stress management than those who graduated school level education from a private school. Conclusions: The results of this study reveal that the status of health promoting behaviors among the students was acceptable with ample room for improvement. Implementation of health education and promotion programs with an emphasis on the different dimensions of health lifestyle behaviors is recommended.
文摘The study is to explore the well-being of nurses in Eastern Taiwan,China and significant predictive factors.Clinical nurses are responsible for improving patient well-being;whereas nurse's perceived well-being and which factors affect the well-being of nurses has not explored.A cross-sectional related survey is on nurses at a teaching hospital in Eastern Taiwan,China.There were 375 nurses completed surveys.The instruments include Well-Being Scale,Work Environment Perception Scale,Health-Promoting Lifestyle Scale and Leisure Coping Strategy Scale.Data were analyzed using descriptive statistic,Spearman's correlation and stepwise regression.Joy and comfort were two major components of nurses'well-being;seven significant predictors explained 63.9%of the variance in the well-being distribution.The findings supported ways to promote the nurses'well-being with the seven significant predictors.These results from the clinical nurses'perspective and provide an evidence for policy development,improve nurses work environment and to promote nurse healthy life and well-being.
文摘Wild species of the subgenus Amygdalus(genus Prunus and family Rosaceae)have been insufficiently studied with regard to their chemical components and their pharmacological potential.The present study aimed at the investigation of the chemical composition of leaves and twigs of A.orientalis Mill.and A.zielinskii Browicz,thus assessing the antioxidant and enzyme inhibiting potential,as well as to define the safety profile.Our results showed that extracts were rich in phenolics,and liquid chromatography-diode array detector-tandem mass spectrometry(LC-DAD-MS)analysis allowed the identification of phenolic acids,flavonoids,coumarins,proanthocyanins,amino acids,fatty acids and derivatives.The assessment of the antioxidant potential demon-strated that the ethyl acetate extract of A.zielinskii twigs recorded the highest anti-ABTS(2,2′-Azino-bis(3-eth-ylbenzothiazoline-6-sulfonic acid))(1298.10 mg trolox equivalent(TE)/g),total antioxidant(4.98 mmol TE/g),Cu^(++)(1211.47 mg TE/g)and Fe^(+++)(907.86 mg TE/g)reducing properties.In addition,it also had the highest anti-DPPH(2,2-diphenyl-1-picrylhydrazyl)activity(560.17 mg TE/g),together with its methanolic extract and that of A.orientalis twigs,whereas the best chelation power was exerted by the ethyl acetate extract of A.orientalis leaves(31.10 mg EDTAE/g).Regarding enzyme inhibition,methanolic extracts of the leaves and twigs of both species displayed the highestα-glucosidase and tyrosinase inhibitory activity,while ethyl acetate extracts of A.orientalis twigs and leaves revealed the best butyrylcholinesterase(2.35 mg galantamine equivalent(GALAE)/g)inhibitory activity.Docking studies demonstrated strong binding affinities of compounds like rutin,kaempferol derivatives,and isorhamnetin-3-O-rutinoside with the abovementioned enzymes,supporting the consistent inhibitory potential.Moreover,we investigated the potential cytotoxicity of these extracts in different human cell lines,thus proving their safety.These results highlight the potential of the two Amygdalus species as a new source of bioactive molecules for the development of health-promoting applications.
基金funded with Grant PID2021-123857OB-I00 by the Spanish Ministry of Science,Innovation and Universities(MICIU),the Spanish State Research Agency(AEI)/10.13039/501100011033 and by FEDER“ERDF/EU”.
文摘The growing availability of horticultural by-products presents an opportunity for their sustainable use as sources of bioactive compounds with potential health benefits.In this study,the phytochemical composition(including polyphenols,terpenoids,and sulfur-containing compounds)and in vitro biological activities of 9 by-products from citrus,pomegranate,broccoli,tomato,and carrot were quantitatively assessed.Pomegranate peels-particularly from the’Wonderful’cultivar-showed the highest antioxidant capacity(ABTS^(+):1297.2 mmol Trolox/kg dw)and strongest inhibitory activity againstα-glucosidase(IC_(50):0.1 mg/mL),α-amylase(17.3 mg/mL),and pancreatic lipase(0.3 mg/mL),associated with high levels of punicalagins and ellagic acid derivatives.Broccoli by-products,notably florets and leaves,were richer in sulforaphane and glucosinolates and showed relevant inhibitory effects on acetylcholinesterase(AChE)and butyrylcholinesterase(BuChE),with IC_(50)values as low as 103.3 mg/mL and 54.1 mg/mL,respectively.Pearson correlation and regression analyses revealed enzyme-specific phytochemical signatures:α-glucosidase inhibition was strongly associated with punicalagins and ellagic acid(r>0.95),lipase inhibition with total polyphenols,and cholinesterase inhibition with sulforaphane and glucosinolates.These findings demonstrate the functional potential of selected horticultural byproducts for targeted nutraceutical applications,particularly in the prevention of metabolic and neurodegenerative disorders.
基金supported and funded by the Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University(IMSIU)(grant number IMSIU-DDRSP2601).
文摘Coconut oil(CO)has recently gained increasing scientific and industrial attention owing to its rich profile of medium-chain fatty acids(MCFAs)and diverse bioactive constituents.These unique components confer promising nutraceutical and functional properties relevant to both human health and sustainable livestock production.This review aims to provide an updated and integrative overview of the biological roles and mechanisms of coconut oil,emphasizing its potential applications in animal nutrition and health promotion.Coconut oil exhibits a wide spectrum of biological activities,including antimicrobial,antioxidant,anti-inflammatory,hepatoprotective,neuroprotective,and metabolic regulatory effects.These functions are primarily mediated through modulation of oxidative stress,lipid metabolism,and inflammatory signaling pathways.In animal production,dietary inclusion of coconut oil has been shown to improve growth performance,immune responses,and product quality,although some findings remain inconsistent and context dependent.Despite the increasing interest in its health benefits,clinical validation of coconut oil's long-term effects in humans and animals remains limited.Therefore,understanding its mechanisms of action and standardizing dosages are crucial to ensure safe and effective utilization.In summary,coconut oil represents a promising natural ingredient that bridges human nutrition and sustainable livestock production.However,further mechanistic and clinical investigations are warranted to substantiate its long-term functional and health-promoting effects.
文摘Camels,particularly dromedaries,are vital to arid and semi-arid regions like Northeast Africa and Asia,where they thrive and provide essential nutrition.Camel milk is rich in essential vitamins(A,B,C,E),minerals(iron,zinc,magnesium),and bioactive compounds,making it a valuable dietary source in resource-limited environments.Camel milk contains protective proteins such as lactoferrin,immunoglobulins,and lactoperoxidases,and these proteins generate bioactive peptides upon digestion that exhibit auspicious antidiabetic,anticancer,antihypertensive,antioxidant,antimicrobial,and hypocholesterolemic activities.While,low cholesterol and sugar levels in camel milk,combined with its insulin-like and anti-inflammatory properties,confer the potential therapeutic attributes against some conditions such as diabetes,autism,and autoimmune diseases.These unique properties of camel milk especially camel milk proteins have significant potential in food applications while a few of its industrial applications in food products like cheese,ice cream,milk powders and ice cream have also been discussed.This review is aimed to comprehensively review camel milk by going through its particular composition,nutritional and bioactive profile,associated health benefits,and industrial applications.
基金supported by funding from Natural Science Founda-tion of China(32172187,31771961)Chinese Postdoctoral Science Foundation(2023M731377,2023M661761)Science&Technology Platform Construction Program of Jiangxi Province.
文摘Grifola frondosa is a highly valuable edible and medicinal fungus with significant health benefits.In traditional Chinese medicine,has been extensively utilized for its therapeutic properties,playing a vital role in treating various diseases related to immune modulation and inflammation.Polysaccharides are the main active com-pound in G.frondosa,and their biological activities are closely related to their composition.The Grifola frondosa polysaccharides(GFPs)interact with key immune receptors such as Toll-like receptors and Dectin-1,which activate macrophages,natural killer cells,and dendritic cells.This interaction enhances the immune system’s capacity to mount effective responses against infections and malignancies.These polysaccharides control glucose metabolism and regulate insulin sensitivity,indicating their potential for managing and preventing metabolic disorders like diabetes.Although the preclinical studies are promising,further research is essential to standardize extraction techniques,conform clinical efficacy,and clarify the mechanism of health benefits.This review provides a comprehensive overview of recent advances in the production,properties,structural characteristics,and biological activities of GFPs.It highlights their therapeutic potential and promotes further research to support their development and application in functional foods,nutraceuticals,and pharmaceutical formulation.
基金supported by Zhejiang Province Philosophy and Social Sciences Emerging(Cross disciplinary)Major Project“Research on Public Risk Perception,Behavior Rules and Countermeasures under Major Public Health Emergencies”,an emerging(crossover)major project of Philosophy and Social Sciences in Zhejiang Province in 2021(21XXJC04ZD).
文摘In the context of a global public health crisis,such as COVID-19,developing interventions to improve population health behav-iors has emerged as a pivotal element of health management strategies.The efficacy of various interventions implemented during this period has varied,and the impact of different variables on these intervention outcomes remains to be fully elucidated.This study screened 57 papers(n=47,264)by searching electronic databases and revealed the optimal intervention through pairwise meta-analysis and network meta-analysis,as well as the changes in intervention effectiveness under different conditions.Our research findings indicate that interventions for preventive health behaviors and health-promoting behaviors have significant effects.For preventive health behaviors,the intervention method of health education and low-risk information framework under information intervention was the optimal intervention.For health-promoting behaviors,the exercise intervention and the prosocial information framework with information intervention were the optimal interventions.Accordingly,future research should focus on the in-depth exploration of specific interventions to establish and improve the effectiveness of interventions.
