Male infertility has been regarded as a significant public health concern,with a cumulative total of 55 million men affected across the globe[1].A wide range of causes,including hormonal imbalance,physical abnormaliti...Male infertility has been regarded as a significant public health concern,with a cumulative total of 55 million men affected across the globe[1].A wide range of causes,including hormonal imbalance,physical abnormalities,lifestyle parameters,chromosomal defects,psychological concerns,etc.,cumulatively account for 30%of male infertility cases[1].These estimates emphasize the urgent need to raise awareness,conduct thorough evaluations,and implement targeted measures to address male infertility effectively[1].展开更多
The coronavirus disease 2019(COVID-19)pandemic is challenging the current public health emergency response systems(PHERSs)of many countries.Although environmental factors,such as those influencing the survival of viru...The coronavirus disease 2019(COVID-19)pandemic is challenging the current public health emergency response systems(PHERSs)of many countries.Although environmental factors,such as those influencing the survival of viruses and their transmission between species including humans,play important roles in PHERSs,little attention has been given to these factors.This study describes and elucidates the roles of environmental factors in future PHERSs.To improve countries’capability to respond to public health emergencies associated with viral infections such as the COVID-19 pandemic,a number of environmental factors should be considered before,during,and after the responses to such emergencies.More specifically,to prevent pandemic outbreaks,we should strengthen environmental and wildlife protection,conduct detailed viral surveillance in animals and hotspots,and improve early-warning systems.During the pandemic,we must study the impacts of environmental factors on viral behaviors,develop control measures to minimize secondary environmental risks,and conduct timely assessments of viral risks and secondary environmental effects with a view to reducing the impacts of the pandemic on human health and on ecosystems.After the pandemic,we should further strengthen surveillance for viruses and the prevention of viral spread,maintain control measures for minimizing secondary environmental risks,develop our capability to scientifically predict pandemics and resurgences,and prepare for the next unexpected resurgence.Meanwhile,we should restore the normal life and production of the public based on the“One Health”concept,that views global human and environmental health as inextricably linked.Our recommendations are essential for improving nations’capability to respond to global public health emergencies.展开更多
Facing the global pandemic of coronavirus disease 2019(CovID-19),countries and regions have implemented different policies and non-pharmacological interventions(NPIs)according to their circumstances.These policies and...Facing the global pandemic of coronavirus disease 2019(CovID-19),countries and regions have implemented different policies and non-pharmacological interventions(NPIs)according to their circumstances.These policies and intervention measures provide new insights into assessing local resilience from the perspective of response capacities in the public health system.This study aims to establish a multi-dimensional and dynamic resilience assessment model based on the index system method.The complete assessment model includes building a comprehensive system,executing the system in specific scenarios,and measuring resilience.The comprehensive system,like a guideline,is constructed from six key categories.The system involves the entire society,encompassing various levels,including country,state,province,city,local community,and individual.It considers not only policy formulation but also the actual implementation of the policy.The comprehensive system does not necessarily apply to all scenarios during the system's implementation.The actual case,the prevention&control in England,is introduced to assess the local resilience and verify the proposed assessment model.The results prove that our model can be used to assess local resilience for the public health system and seek capacity improvement when responding to epidemic situations.展开更多
Introduction:The National Emergency Response Team of Infectious Disease(NERID)constitutes the cornerstone of China’s public health emergency response infrastructure.This study systematically evaluates NERID’s curren...Introduction:The National Emergency Response Team of Infectious Disease(NERID)constitutes the cornerstone of China’s public health emergency response infrastructure.This study systematically evaluates NERID’s current management practices and capacity-building initiatives,examining regional variations to establish an evidence base for advancing team modernization and standardization.Methods:We conducted a comprehensive questionnaire survey of all 20 NERID teams in China during November 2023.Descriptive analyses examined four core domains:team construction,management systems,capacity building,and emergency response operations.Two novel metrics were developed to quantify preparedness activities:the Training Intensity Index and the Drill Intensity Index.Results:This investigation represents the first nationwide assessment of NERID development and management,encompassing 20 teams distributed across seven geographic regions.Critical findings demonstrated that full-time staff comprised only 21.1%of management personnel,while equipment standardization remained insufficient,with unified coding systems implemented in merely 45%of teams.Substantial regional disparities emerged in training and drill activities.Teams averaged two training sessions and three drills annually,with mean participation of 79 and 45 individuals per session,respectively.These metrics yielded a Training Intensity Index of 125 person-times per year and a Drill Intensity Index of 121 person-times per year.Conclusion:China has established a national-level health emergency response team network with nationwide coverage,achieving unified command and resource coordination.Beyond strengthening routine training and drills,implementing comprehensive multi-scenario and multi-mode exercises is essential to enhance operational readiness and response capabilities.展开更多
In the engineering practice, merging statistical analysis into structural evaluation and assessment is a tendency in the future. As a combination of mathematical and statistical techniques, response surface (RS) met...In the engineering practice, merging statistical analysis into structural evaluation and assessment is a tendency in the future. As a combination of mathematical and statistical techniques, response surface (RS) methodology has been successfully applied to design optimization, response prediction and model validation. With the aid of RS methodology, these two serial papers present a finite element (FE) model updating and validation method for bridge structures based on structural health monitoring. The key issues to implement such a model updating are discussed in this paper, such as design of experiment, parameter screening, construction of high-order polynomial response surface model, optimization methods and precision inspection of RS model. The proposed procedure is illustrated by a prestressed concrete continuous rigid-frame bridge monitored under operational conditions. The results from the updated FE model have been compared with those obtained from online health monitoring system. The real application to a full-size bridge has demonstrated that the FE model updating process is efficient and convenient. The updated FE model can relatively reflect the actual condition of Xiabaishi Bridge in the design space of parameters and can be further applied to FE model validation and damage identification.展开更多
The current study discusses the social and psychological studies conducted on the concept of the social responsibility, as well as the symbolic interactive trend as a theoretical basis for interpretation; moreover, di...The current study discusses the social and psychological studies conducted on the concept of the social responsibility, as well as the symbolic interactive trend as a theoretical basis for interpretation; moreover, discussing the social responsibility in the light of family variables. The aim of this study is to investigate the family variables, including domicile, parents' education, their age, the type of work they do, family size, and family income. As to the social responsibility's dimensions for sample selected for this study; hence, it includes personal, ethical, national, environmental, health, and social responsibility. The current study adopted the descriptive approach along with a demographic data form and the social responsibility's scale. The sample selected consisted of 330 female students from various colleges within King Abdulaziz University. The results indicated that there was an impact on all the variables, thus such impact was in favor of those living in rural areas as to the ethical dimension and in favor of urban people as to the dimensions of accountability, parents' level of education, parents' seniority, working mothers, greater family size, and higher income.展开更多
The world must act fast to contain wider international spread of the epidemic of COVID-19 now.The unprecedented public health efforts in China have contained the spread of this new virus.Measures taken in China are cu...The world must act fast to contain wider international spread of the epidemic of COVID-19 now.The unprecedented public health efforts in China have contained the spread of this new virus.Measures taken in China are currently proven to reduce human-to-human transmission successfully.We summarized the effective intervention and prevention measures in the fields of public health response,clinical management,and research development in China,which may provide vital lessons for the global response.It is really important to take collaborative actions now to save more lives from the pandemic of COVID-19.展开更多
文摘Male infertility has been regarded as a significant public health concern,with a cumulative total of 55 million men affected across the globe[1].A wide range of causes,including hormonal imbalance,physical abnormalities,lifestyle parameters,chromosomal defects,psychological concerns,etc.,cumulatively account for 30%of male infertility cases[1].These estimates emphasize the urgent need to raise awareness,conduct thorough evaluations,and implement targeted measures to address male infertility effectively[1].
基金the National Science Foundation of China(41925031,41991315,and 41521003).
文摘The coronavirus disease 2019(COVID-19)pandemic is challenging the current public health emergency response systems(PHERSs)of many countries.Although environmental factors,such as those influencing the survival of viruses and their transmission between species including humans,play important roles in PHERSs,little attention has been given to these factors.This study describes and elucidates the roles of environmental factors in future PHERSs.To improve countries’capability to respond to public health emergencies associated with viral infections such as the COVID-19 pandemic,a number of environmental factors should be considered before,during,and after the responses to such emergencies.More specifically,to prevent pandemic outbreaks,we should strengthen environmental and wildlife protection,conduct detailed viral surveillance in animals and hotspots,and improve early-warning systems.During the pandemic,we must study the impacts of environmental factors on viral behaviors,develop control measures to minimize secondary environmental risks,and conduct timely assessments of viral risks and secondary environmental effects with a view to reducing the impacts of the pandemic on human health and on ecosystems.After the pandemic,we should further strengthen surveillance for viruses and the prevention of viral spread,maintain control measures for minimizing secondary environmental risks,develop our capability to scientifically predict pandemics and resurgences,and prepare for the next unexpected resurgence.Meanwhile,we should restore the normal life and production of the public based on the“One Health”concept,that views global human and environmental health as inextricably linked.Our recommendations are essential for improving nations’capability to respond to global public health emergencies.
基金supported by the National Key R&D Program of China(2021ZD0111203)the National Science Foundation of China(Grant Nos.72004113,72274123,72174099)+2 种基金the Bill&Melinda Gates Foundation:COVID-19 Emergency and Pandemic Response Program(INV-005832)the Key Soft Science Project of Shanghai(21692104800)the High-tech Discipline Construction Fundings for Universities in Beijing(Safety Science and Engineering).
文摘Facing the global pandemic of coronavirus disease 2019(CovID-19),countries and regions have implemented different policies and non-pharmacological interventions(NPIs)according to their circumstances.These policies and intervention measures provide new insights into assessing local resilience from the perspective of response capacities in the public health system.This study aims to establish a multi-dimensional and dynamic resilience assessment model based on the index system method.The complete assessment model includes building a comprehensive system,executing the system in specific scenarios,and measuring resilience.The comprehensive system,like a guideline,is constructed from six key categories.The system involves the entire society,encompassing various levels,including country,state,province,city,local community,and individual.It considers not only policy formulation but also the actual implementation of the policy.The comprehensive system does not necessarily apply to all scenarios during the system's implementation.The actual case,the prevention&control in England,is introduced to assess the local resilience and verify the proposed assessment model.The results prove that our model can be used to assess local resilience for the public health system and seek capacity improvement when responding to epidemic situations.
基金Supported by the Commissioned Project of the National Disease Control and Prevention Administration(01124).
文摘Introduction:The National Emergency Response Team of Infectious Disease(NERID)constitutes the cornerstone of China’s public health emergency response infrastructure.This study systematically evaluates NERID’s current management practices and capacity-building initiatives,examining regional variations to establish an evidence base for advancing team modernization and standardization.Methods:We conducted a comprehensive questionnaire survey of all 20 NERID teams in China during November 2023.Descriptive analyses examined four core domains:team construction,management systems,capacity building,and emergency response operations.Two novel metrics were developed to quantify preparedness activities:the Training Intensity Index and the Drill Intensity Index.Results:This investigation represents the first nationwide assessment of NERID development and management,encompassing 20 teams distributed across seven geographic regions.Critical findings demonstrated that full-time staff comprised only 21.1%of management personnel,while equipment standardization remained insufficient,with unified coding systems implemented in merely 45%of teams.Substantial regional disparities emerged in training and drill activities.Teams averaged two training sessions and three drills annually,with mean participation of 79 and 45 individuals per session,respectively.These metrics yielded a Training Intensity Index of 125 person-times per year and a Drill Intensity Index of 121 person-times per year.Conclusion:China has established a national-level health emergency response team network with nationwide coverage,achieving unified command and resource coordination.Beyond strengthening routine training and drills,implementing comprehensive multi-scenario and multi-mode exercises is essential to enhance operational readiness and response capabilities.
基金supported by the National Natural Science Foundation of China(No.51178101,51378112)National Scientific and Technological Supporting Plan(No.2011BAK02B03)Scientific Research and Development Foundation of Fujian University of Technology(No.GY-Z10085)
文摘In the engineering practice, merging statistical analysis into structural evaluation and assessment is a tendency in the future. As a combination of mathematical and statistical techniques, response surface (RS) methodology has been successfully applied to design optimization, response prediction and model validation. With the aid of RS methodology, these two serial papers present a finite element (FE) model updating and validation method for bridge structures based on structural health monitoring. The key issues to implement such a model updating are discussed in this paper, such as design of experiment, parameter screening, construction of high-order polynomial response surface model, optimization methods and precision inspection of RS model. The proposed procedure is illustrated by a prestressed concrete continuous rigid-frame bridge monitored under operational conditions. The results from the updated FE model have been compared with those obtained from online health monitoring system. The real application to a full-size bridge has demonstrated that the FE model updating process is efficient and convenient. The updated FE model can relatively reflect the actual condition of Xiabaishi Bridge in the design space of parameters and can be further applied to FE model validation and damage identification.
文摘The current study discusses the social and psychological studies conducted on the concept of the social responsibility, as well as the symbolic interactive trend as a theoretical basis for interpretation; moreover, discussing the social responsibility in the light of family variables. The aim of this study is to investigate the family variables, including domicile, parents' education, their age, the type of work they do, family size, and family income. As to the social responsibility's dimensions for sample selected for this study; hence, it includes personal, ethical, national, environmental, health, and social responsibility. The current study adopted the descriptive approach along with a demographic data form and the social responsibility's scale. The sample selected consisted of 330 female students from various colleges within King Abdulaziz University. The results indicated that there was an impact on all the variables, thus such impact was in favor of those living in rural areas as to the ethical dimension and in favor of urban people as to the dimensions of accountability, parents' level of education, parents' seniority, working mothers, greater family size, and higher income.
基金This work is funded by Medicine and Engineering Interdisciplinary Research Fund of Shanghai Jiao Tong University(No.YG2020YQ06)the National Key Research and Development Project(Nos.2018YFC1705100 and 2018YFC1705103)the National Natural Science Foundation of China(No.71673187)。
文摘The world must act fast to contain wider international spread of the epidemic of COVID-19 now.The unprecedented public health efforts in China have contained the spread of this new virus.Measures taken in China are currently proven to reduce human-to-human transmission successfully.We summarized the effective intervention and prevention measures in the fields of public health response,clinical management,and research development in China,which may provide vital lessons for the global response.It is really important to take collaborative actions now to save more lives from the pandemic of COVID-19.