Objective:To determine the delta-9-tetrahydrocannabinol(THC)content of cannabis seizures in Egypt.Methods:Unheated and heated extracts of cannabis seizures were prepared from the dried flowering tops and leaves(mariju...Objective:To determine the delta-9-tetrahydrocannabinol(THC)content of cannabis seizures in Egypt.Methods:Unheated and heated extracts of cannabis seizures were prepared from the dried flowering tops and leaves(marijuana)or from the resin(hashish)and subjected to analysis using high performance liquid chromatography(HPLC).Results:The heated resin extract had the peak of THC in a relative ratio of 31.34%,while extracting the resin directly without heating contained only 18.34%of THC.On the other hand,marijuana showed minimum percentage of THC at 11.188% on heating and 9.55% without heating.Conclusions:These results indicate the high potency of the abused cannabis plant in the illicit Egyptian market.展开更多
Abundant literature suggests the hypothesis that cannabis use leads to the onset of psychotic symptoms. However, the nature of the association and the causal link remain controversial. This review aims to identify the...Abundant literature suggests the hypothesis that cannabis use leads to the onset of psychotic symptoms. However, the nature of the association and the causal link remain controversial. This review aims to identify the risk factors involved in the etiopathogenesis of psychosis or psychotic features. Our electronic search found 1653 studies published until March 1<sup><span style="font-family:Verdana;">st</span></sup><span style="font-family:Verdana;"> 2020. Longitudinal studies and literature reviews were selected if they addressed specifically the issues of the cannabis/psychosis relationship and the eventual risk factors involved. Our systematic review identified six potential risk factors involved in the association. They are, in decreasing importance, the dose-response relationship (quantity, frequency and duration of cannabis use), the early age of cannabis consumption, genetic susceptibility, childhood trauma, cigarette smoking and urban environment. In contrast, a significant inverse relationship exists between cannabidiol (CBD) and psychosis: cannabidiol is associated with less psychotic symptoms and manifests antipsychotic properties. Further studies are needed to establish a clear causal relationship between cannabis and psychosis and to identify the qualitative and quantitative contribution of specific risk factors on its onset and sustainability.</span>展开更多
文摘Objective:To determine the delta-9-tetrahydrocannabinol(THC)content of cannabis seizures in Egypt.Methods:Unheated and heated extracts of cannabis seizures were prepared from the dried flowering tops and leaves(marijuana)or from the resin(hashish)and subjected to analysis using high performance liquid chromatography(HPLC).Results:The heated resin extract had the peak of THC in a relative ratio of 31.34%,while extracting the resin directly without heating contained only 18.34%of THC.On the other hand,marijuana showed minimum percentage of THC at 11.188% on heating and 9.55% without heating.Conclusions:These results indicate the high potency of the abused cannabis plant in the illicit Egyptian market.
文摘Abundant literature suggests the hypothesis that cannabis use leads to the onset of psychotic symptoms. However, the nature of the association and the causal link remain controversial. This review aims to identify the risk factors involved in the etiopathogenesis of psychosis or psychotic features. Our electronic search found 1653 studies published until March 1<sup><span style="font-family:Verdana;">st</span></sup><span style="font-family:Verdana;"> 2020. Longitudinal studies and literature reviews were selected if they addressed specifically the issues of the cannabis/psychosis relationship and the eventual risk factors involved. Our systematic review identified six potential risk factors involved in the association. They are, in decreasing importance, the dose-response relationship (quantity, frequency and duration of cannabis use), the early age of cannabis consumption, genetic susceptibility, childhood trauma, cigarette smoking and urban environment. In contrast, a significant inverse relationship exists between cannabidiol (CBD) and psychosis: cannabidiol is associated with less psychotic symptoms and manifests antipsychotic properties. Further studies are needed to establish a clear causal relationship between cannabis and psychosis and to identify the qualitative and quantitative contribution of specific risk factors on its onset and sustainability.</span>
