Since the discovery of oceanic manganese nodules during the expedition of the British ocean-going ship Challenger from 1872 to 1876, research and development for seabed manganese nodules have never ceased owing to the...Since the discovery of oceanic manganese nodules during the expedition of the British ocean-going ship Challenger from 1872 to 1876, research and development for seabed manganese nodules have never ceased owing to the huge economic inducements. Manganese nodules are the black or dark brown, spherical or massive Mn-bearing ores, deposits of which are found on the sea bottom. The nodules are a mixture of silicate and insoluble potassium permanganates （also with sub-Ti, Fe and Na permanganates） that contain more than 30 kinds of metallic elements, among which those of greatest economic interest are Mn （27-30%）, Ni（1.25-1.5%）, Cu（1- 1.4%）, Co（0.2- 0.25 %）, Fe, Si, and AI, with minor amounts of Ca, Na, K, Ti, B, H and O.展开更多
The Bayan Har block,one of China's most seismically active regions,has experienced multiple major earthquakes(≥M 7.0)in recent years.It is a key area for investigating the interactions between the Qinghai-Xizang(...The Bayan Har block,one of China's most seismically active regions,has experienced multiple major earthquakes(≥M 7.0)in recent years.It is a key area for investigating the interactions between the Qinghai-Xizang(Qingzang)Plateau and adjacent blocks,plateau uplift,and strong earthquake mechanisms.P-wave velocity and crustal composition provide key constraints on the properties of distinct tectonic units and their evolutionary modification processes.Based on the results of 8 Deep Seismic Sounding(DSS)profiles completed in the Bayan Har block and surrounding areas over the past 20 years,We constructed one-dimensional P-wave velocity models for the crust of Bayan Har block,Qilian fold belt,Qinling fold belt,Alxa block,Ordos block and Sichuan basin.Furthermore,crustal composition models for different tectonic units were established based on these results.The results reveal that the crustal thickness of the Bayan Har block gradually decreases towards the NNE,NE,and SE directions,while the average crustal velocity increases correspondingly.The felsic layer in the crust accounts for more than half of the total crustal thickness.The mafic content within the crust of different tectonic units exhibits notable variations,which may reflect that the Bayan Har block,Qilian fold belt,and Qinling fold belt have experienced more intensive lithospheric evolution processes compared to Ordos basin and Sichuan basin.The seismicity distribution in this region is significantly controlled by crustal velocity and composition heterogeneity across the Bayan Har block and adjacent areas,which demonstrates that earthquakes within and around the Bayan Har block exhibit both high frequency and larger magnitudes.These seismic characteristics primarily result from intense crustal stress accumulation and release during the outward expansion of the Qingzang Plateau.展开更多
The ISO Annual Meeting is the world’s premier event for the international standards community.This year’s event is hosted by RSB,the national standards body of Rwanda.The theme“United for impact”calls us to harnes...The ISO Annual Meeting is the world’s premier event for the international standards community.This year’s event is hosted by RSB,the national standards body of Rwanda.The theme“United for impact”calls us to harness our collective strength in a world that needs bold,lasting change.The ISO Annual Meeting convenes global leaders and change-makers to explore how international standards can unlock progress,foster trust and drive lasting solutions to our shared challenges.展开更多
The increase in wood and wood-based products in the construction and furniture sectors has grown exponentially,generating severe environmental and socioeconomic impacts.Particleboard panels have been the main cost-ben...The increase in wood and wood-based products in the construction and furniture sectors has grown exponentially,generating severe environmental and socioeconomic impacts.Particleboard panels have been the main cost-benefit option on the market due to their lightness and lower cost compared to solid wood.However,the synthetic adhesives used in producing traditional particleboard panels cause serious harm to human health.Developing particleboard panels with fibrous waste and natural adhesives could be a sustainable alternative for these sectors.The work aimed to create particleboards with fibrous wastes from the pseudostem of the banana tree(Musa paradisiaca)and different proportions of the natural adhesive cassava starch-CS in replacement of synthetic adhesive urea-formaldehyde-UF.Five experimental groups were manufactured with banana trees and different percentages of UF and CS adhesives,namely(100UF–0%CS),(50%UF–50%CS),(30%UF–70%CS),(10%UF–90%CS)and(0%UF–100%CS).The particleboards had their physical-mechanical properties determined.The apparent density values did not show significant variation between the assessed treatments.Regarding the water absorption and thickness swelling,the best performances were observed for the panels made without the addition of CS(100%UF).For the mechanical properties of static bending strength and Janka hardness,it was identified that adding up to 50%CS did not interfere with the quality of the panels.These analyses show that the particleboard panels produced with wastes of the banana tree bonded with natural CS adhesivemay be an economically viable and environmentally correct alternative,positively strengthening the development of sustainable strategies.展开更多
Analyzing physical activities through wearable devices is a promising research area for improving health assessment.This research focuses on the development of an affordable and real-time Human Activity Recognition(HA...Analyzing physical activities through wearable devices is a promising research area for improving health assessment.This research focuses on the development of an affordable and real-time Human Activity Recognition(HAR)system designed to operate on low-performance microcontrollers.The system utilizes data from a bodyworn accelerometer to recognize and classify human activities,providing a cost-effective,easy-to-use,and highly accurate solution.A key challenge addressed in this study is the execution of efficient motion recognition within a resource-constrained environment.The system employs a Random Forest(RF)classifier,which outperforms Gradient Boosting Decision Trees(GBDT),Support Vector Machines(SVM),and K-Nearest Neighbors(KNN)in terms of accuracy and computational efficiency.The proposed features Average absolute deviation(AAD),Standard deviation(STD),Interquartile range(IQR),Range,and Root mean square(RMS).The research has conducted numerous experiments and comparisons to establish optimal parameters for ensuring system effectiveness,including setting a sampling frequency of 50 Hz and selecting an 8-s window size with a 40%overlap between windows.Validation was conducted on both the WISDM public dataset and a self-collected dataset,focusing on five fundamental daily activities:Standing,Sitting,Jogging,Walking,and Walking the stairs.The results demonstrated high recognition accuracy,with the system achieving 96.7%on the WISDM dataset and 97.13%on the collected dataset.This research confirms the feasibility of deploying HAR systems on low-performance microcontrollers and highlights the system’s potential applications in patient support,rehabilitation,and elderly care.展开更多
Autophagy,a conserved cellular degradation process,is crucial for various cellular processes such as immune responses,inflammation,metabolic and oxidative stress adaptation,cell proliferation,development,and tissue re...Autophagy,a conserved cellular degradation process,is crucial for various cellular processes such as immune responses,inflammation,metabolic and oxidative stress adaptation,cell proliferation,development,and tissue repair and remodeling.Dysregulation of autophagy is suspected in numerous diseases,including cancer,neurodegenerative diseases,digestive disorders,metabolic syndromes,and infectious and inflammatory diseases.If autophagy is disrupted,for example,this can have serious consequences and lead to chronic inflammation and tissue damage,as occurs in diseases such as Chron's disease and ulcerative colitis.On the other hand,the influence of autophagy on the development and progression of cancer is not clear.Autophagy can both suppress and promote the progression and metastasis of cancer at various stages.From inflammatory bowel diseases to gastrointestinal cancer,researchers are discovering the intricate role of autophagy in maintaining gut health and its potential as a therapeutic target.Researchers should carefully consider the nature and progression of diseases such as cancer when trying to determine whether inhibiting or stimulating autophagy is likely to be beneficial.Multidisciplinary approaches that combine cutting-edge research with clinical expertise are key to unlocking the full therapeutic potential of autophagy in digestive diseases.展开更多
文摘Since the discovery of oceanic manganese nodules during the expedition of the British ocean-going ship Challenger from 1872 to 1876, research and development for seabed manganese nodules have never ceased owing to the huge economic inducements. Manganese nodules are the black or dark brown, spherical or massive Mn-bearing ores, deposits of which are found on the sea bottom. The nodules are a mixture of silicate and insoluble potassium permanganates （also with sub-Ti, Fe and Na permanganates） that contain more than 30 kinds of metallic elements, among which those of greatest economic interest are Mn （27-30%）, Ni（1.25-1.5%）, Cu（1- 1.4%）, Co（0.2- 0.25 %）, Fe, Si, and AI, with minor amounts of Ca, Na, K, Ti, B, H and O.
基金supported by the National Key R&D Program of China(No.2023YFC3012002)the National Natural Science Foundation of China(42374073)。
文摘The Bayan Har block,one of China's most seismically active regions,has experienced multiple major earthquakes(≥M 7.0)in recent years.It is a key area for investigating the interactions between the Qinghai-Xizang(Qingzang)Plateau and adjacent blocks,plateau uplift,and strong earthquake mechanisms.P-wave velocity and crustal composition provide key constraints on the properties of distinct tectonic units and their evolutionary modification processes.Based on the results of 8 Deep Seismic Sounding(DSS)profiles completed in the Bayan Har block and surrounding areas over the past 20 years,We constructed one-dimensional P-wave velocity models for the crust of Bayan Har block,Qilian fold belt,Qinling fold belt,Alxa block,Ordos block and Sichuan basin.Furthermore,crustal composition models for different tectonic units were established based on these results.The results reveal that the crustal thickness of the Bayan Har block gradually decreases towards the NNE,NE,and SE directions,while the average crustal velocity increases correspondingly.The felsic layer in the crust accounts for more than half of the total crustal thickness.The mafic content within the crust of different tectonic units exhibits notable variations,which may reflect that the Bayan Har block,Qilian fold belt,and Qinling fold belt have experienced more intensive lithospheric evolution processes compared to Ordos basin and Sichuan basin.The seismicity distribution in this region is significantly controlled by crustal velocity and composition heterogeneity across the Bayan Har block and adjacent areas,which demonstrates that earthquakes within and around the Bayan Har block exhibit both high frequency and larger magnitudes.These seismic characteristics primarily result from intense crustal stress accumulation and release during the outward expansion of the Qingzang Plateau.
文摘The ISO Annual Meeting is the world’s premier event for the international standards community.This year’s event is hosted by RSB,the national standards body of Rwanda.The theme“United for impact”calls us to harness our collective strength in a world that needs bold,lasting change.The ISO Annual Meeting convenes global leaders and change-makers to explore how international standards can unlock progress,foster trust and drive lasting solutions to our shared challenges.
基金financed by“Conselho Nacional de Desenvolvimento Cientifico e Tecnologico”(CNPq)and“Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior”(CAPES)-Finance Code 001.
文摘The increase in wood and wood-based products in the construction and furniture sectors has grown exponentially,generating severe environmental and socioeconomic impacts.Particleboard panels have been the main cost-benefit option on the market due to their lightness and lower cost compared to solid wood.However,the synthetic adhesives used in producing traditional particleboard panels cause serious harm to human health.Developing particleboard panels with fibrous waste and natural adhesives could be a sustainable alternative for these sectors.The work aimed to create particleboards with fibrous wastes from the pseudostem of the banana tree(Musa paradisiaca)and different proportions of the natural adhesive cassava starch-CS in replacement of synthetic adhesive urea-formaldehyde-UF.Five experimental groups were manufactured with banana trees and different percentages of UF and CS adhesives,namely(100UF–0%CS),(50%UF–50%CS),(30%UF–70%CS),(10%UF–90%CS)and(0%UF–100%CS).The particleboards had their physical-mechanical properties determined.The apparent density values did not show significant variation between the assessed treatments.Regarding the water absorption and thickness swelling,the best performances were observed for the panels made without the addition of CS(100%UF).For the mechanical properties of static bending strength and Janka hardness,it was identified that adding up to 50%CS did not interfere with the quality of the panels.These analyses show that the particleboard panels produced with wastes of the banana tree bonded with natural CS adhesivemay be an economically viable and environmentally correct alternative,positively strengthening the development of sustainable strategies.
基金Human activity data for the experiments were sourced from the Ethics Council for Grassroots Biomedical Research at Phenikaa University.The data collection adhered to Decision No.476/QD-DHP-HÐÐÐthe Ethics Council for Grassroots Biomedical Research at Phenikaa University(No.023.07.01/DHP-HÐÐÐ,2023 Dec).
文摘Analyzing physical activities through wearable devices is a promising research area for improving health assessment.This research focuses on the development of an affordable and real-time Human Activity Recognition(HAR)system designed to operate on low-performance microcontrollers.The system utilizes data from a bodyworn accelerometer to recognize and classify human activities,providing a cost-effective,easy-to-use,and highly accurate solution.A key challenge addressed in this study is the execution of efficient motion recognition within a resource-constrained environment.The system employs a Random Forest(RF)classifier,which outperforms Gradient Boosting Decision Trees(GBDT),Support Vector Machines(SVM),and K-Nearest Neighbors(KNN)in terms of accuracy and computational efficiency.The proposed features Average absolute deviation(AAD),Standard deviation(STD),Interquartile range(IQR),Range,and Root mean square(RMS).The research has conducted numerous experiments and comparisons to establish optimal parameters for ensuring system effectiveness,including setting a sampling frequency of 50 Hz and selecting an 8-s window size with a 40%overlap between windows.Validation was conducted on both the WISDM public dataset and a self-collected dataset,focusing on five fundamental daily activities:Standing,Sitting,Jogging,Walking,and Walking the stairs.The results demonstrated high recognition accuracy,with the system achieving 96.7%on the WISDM dataset and 97.13%on the collected dataset.This research confirms the feasibility of deploying HAR systems on low-performance microcontrollers and highlights the system’s potential applications in patient support,rehabilitation,and elderly care.
文摘Autophagy,a conserved cellular degradation process,is crucial for various cellular processes such as immune responses,inflammation,metabolic and oxidative stress adaptation,cell proliferation,development,and tissue repair and remodeling.Dysregulation of autophagy is suspected in numerous diseases,including cancer,neurodegenerative diseases,digestive disorders,metabolic syndromes,and infectious and inflammatory diseases.If autophagy is disrupted,for example,this can have serious consequences and lead to chronic inflammation and tissue damage,as occurs in diseases such as Chron's disease and ulcerative colitis.On the other hand,the influence of autophagy on the development and progression of cancer is not clear.Autophagy can both suppress and promote the progression and metastasis of cancer at various stages.From inflammatory bowel diseases to gastrointestinal cancer,researchers are discovering the intricate role of autophagy in maintaining gut health and its potential as a therapeutic target.Researchers should carefully consider the nature and progression of diseases such as cancer when trying to determine whether inhibiting or stimulating autophagy is likely to be beneficial.Multidisciplinary approaches that combine cutting-edge research with clinical expertise are key to unlocking the full therapeutic potential of autophagy in digestive diseases.
基金National Natural Science Foundation of China(Nos.62371118,6210020445 and 61901104)Natural Science Foundation of Shanghai,China(Nos.21ZR1446900 and 21511100102)Science and Technology Research Project of Shanghai Songjiang District,China(No.20SJKJGG4C)。
