The Bayan Har block,one of China's most seismically active regions,has experienced multiple major earthquakes(≥M 7.0)in recent years.It is a key area for investigating the interactions between the Qinghai-Xizang(...The Bayan Har block,one of China's most seismically active regions,has experienced multiple major earthquakes(≥M 7.0)in recent years.It is a key area for investigating the interactions between the Qinghai-Xizang(Qingzang)Plateau and adjacent blocks,plateau uplift,and strong earthquake mechanisms.P-wave velocity and crustal composition provide key constraints on the properties of distinct tectonic units and their evolutionary modification processes.Based on the results of 8 Deep Seismic Sounding(DSS)profiles completed in the Bayan Har block and surrounding areas over the past 20 years,We constructed one-dimensional P-wave velocity models for the crust of Bayan Har block,Qilian fold belt,Qinling fold belt,Alxa block,Ordos block and Sichuan basin.Furthermore,crustal composition models for different tectonic units were established based on these results.The results reveal that the crustal thickness of the Bayan Har block gradually decreases towards the NNE,NE,and SE directions,while the average crustal velocity increases correspondingly.The felsic layer in the crust accounts for more than half of the total crustal thickness.The mafic content within the crust of different tectonic units exhibits notable variations,which may reflect that the Bayan Har block,Qilian fold belt,and Qinling fold belt have experienced more intensive lithospheric evolution processes compared to Ordos basin and Sichuan basin.The seismicity distribution in this region is significantly controlled by crustal velocity and composition heterogeneity across the Bayan Har block and adjacent areas,which demonstrates that earthquakes within and around the Bayan Har block exhibit both high frequency and larger magnitudes.These seismic characteristics primarily result from intense crustal stress accumulation and release during the outward expansion of the Qingzang Plateau.展开更多
Analyzing physical activities through wearable devices is a promising research area for improving health assessment.This research focuses on the development of an affordable and real-time Human Activity Recognition(HA...Analyzing physical activities through wearable devices is a promising research area for improving health assessment.This research focuses on the development of an affordable and real-time Human Activity Recognition(HAR)system designed to operate on low-performance microcontrollers.The system utilizes data from a bodyworn accelerometer to recognize and classify human activities,providing a cost-effective,easy-to-use,and highly accurate solution.A key challenge addressed in this study is the execution of efficient motion recognition within a resource-constrained environment.The system employs a Random Forest(RF)classifier,which outperforms Gradient Boosting Decision Trees(GBDT),Support Vector Machines(SVM),and K-Nearest Neighbors(KNN)in terms of accuracy and computational efficiency.The proposed features Average absolute deviation(AAD),Standard deviation(STD),Interquartile range(IQR),Range,and Root mean square(RMS).The research has conducted numerous experiments and comparisons to establish optimal parameters for ensuring system effectiveness,including setting a sampling frequency of 50 Hz and selecting an 8-s window size with a 40%overlap between windows.Validation was conducted on both the WISDM public dataset and a self-collected dataset,focusing on five fundamental daily activities:Standing,Sitting,Jogging,Walking,and Walking the stairs.The results demonstrated high recognition accuracy,with the system achieving 96.7%on the WISDM dataset and 97.13%on the collected dataset.This research confirms the feasibility of deploying HAR systems on low-performance microcontrollers and highlights the system’s potential applications in patient support,rehabilitation,and elderly care.展开更多
Autophagy,a conserved cellular degradation process,is crucial for various cellular processes such as immune responses,inflammation,metabolic and oxidative stress adaptation,cell proliferation,development,and tissue re...Autophagy,a conserved cellular degradation process,is crucial for various cellular processes such as immune responses,inflammation,metabolic and oxidative stress adaptation,cell proliferation,development,and tissue repair and remodeling.Dysregulation of autophagy is suspected in numerous diseases,including cancer,neurodegenerative diseases,digestive disorders,metabolic syndromes,and infectious and inflammatory diseases.If autophagy is disrupted,for example,this can have serious consequences and lead to chronic inflammation and tissue damage,as occurs in diseases such as Chron's disease and ulcerative colitis.On the other hand,the influence of autophagy on the development and progression of cancer is not clear.Autophagy can both suppress and promote the progression and metastasis of cancer at various stages.From inflammatory bowel diseases to gastrointestinal cancer,researchers are discovering the intricate role of autophagy in maintaining gut health and its potential as a therapeutic target.Researchers should carefully consider the nature and progression of diseases such as cancer when trying to determine whether inhibiting or stimulating autophagy is likely to be beneficial.Multidisciplinary approaches that combine cutting-edge research with clinical expertise are key to unlocking the full therapeutic potential of autophagy in digestive diseases.展开更多
At present,there are unharmonious factors existing in Chinese family education,which particular manifest in the means of family education.The Three Character Primer,as an epitome of the essence of Chinese traditional ...At present,there are unharmonious factors existing in Chinese family education,which particular manifest in the means of family education.The Three Character Primer,as an epitome of the essence of Chinese traditional culture,can provide enlightenment on building a democratic and harmonious family education means.展开更多
为探究中国铜期货市场价格波动的变化规律并以此预测其风险值,以沪铜期货高频价格数据为样本,综合考虑其收益率波动的聚集性、偏峰厚尾性与长记忆性,将广义已实现测度引入偏t分布假设下的Realized GARCH模型与拓展的Realized HAR GARCH...为探究中国铜期货市场价格波动的变化规律并以此预测其风险值,以沪铜期货高频价格数据为样本,综合考虑其收益率波动的聚集性、偏峰厚尾性与长记忆性,将广义已实现测度引入偏t分布假设下的Realized GARCH模型与拓展的Realized HAR GARCH模型中,并通过样本内拟合与样本外滚动预测,结合似然函数、VaR后验测试与损失函数MCS检验法综合比较了采用不同已实现测度的Realized GARCH以及Realized HAR GARCH模型在沪铜期货收益波动率估计和VaR预测上的效果。实证结果显示:对于沪铜期货市场而言,无论是波动率估计还是风险预测,广义已实现测度的引入显著地提升了Realized GARCH与Realized HAR GARCH模型的拟合效果与预测能力,其中基于日内损失RMAD与RES测度下的Realized HAR GARCH模型分别拥有最优的估计与预测表现。展开更多
基金supported by the National Key R&D Program of China(No.2023YFC3012002)the National Natural Science Foundation of China(42374073)。
文摘The Bayan Har block,one of China's most seismically active regions,has experienced multiple major earthquakes(≥M 7.0)in recent years.It is a key area for investigating the interactions between the Qinghai-Xizang(Qingzang)Plateau and adjacent blocks,plateau uplift,and strong earthquake mechanisms.P-wave velocity and crustal composition provide key constraints on the properties of distinct tectonic units and their evolutionary modification processes.Based on the results of 8 Deep Seismic Sounding(DSS)profiles completed in the Bayan Har block and surrounding areas over the past 20 years,We constructed one-dimensional P-wave velocity models for the crust of Bayan Har block,Qilian fold belt,Qinling fold belt,Alxa block,Ordos block and Sichuan basin.Furthermore,crustal composition models for different tectonic units were established based on these results.The results reveal that the crustal thickness of the Bayan Har block gradually decreases towards the NNE,NE,and SE directions,while the average crustal velocity increases correspondingly.The felsic layer in the crust accounts for more than half of the total crustal thickness.The mafic content within the crust of different tectonic units exhibits notable variations,which may reflect that the Bayan Har block,Qilian fold belt,and Qinling fold belt have experienced more intensive lithospheric evolution processes compared to Ordos basin and Sichuan basin.The seismicity distribution in this region is significantly controlled by crustal velocity and composition heterogeneity across the Bayan Har block and adjacent areas,which demonstrates that earthquakes within and around the Bayan Har block exhibit both high frequency and larger magnitudes.These seismic characteristics primarily result from intense crustal stress accumulation and release during the outward expansion of the Qingzang Plateau.
基金Human activity data for the experiments were sourced from the Ethics Council for Grassroots Biomedical Research at Phenikaa University.The data collection adhered to Decision No.476/QD-DHP-HÐÐÐthe Ethics Council for Grassroots Biomedical Research at Phenikaa University(No.023.07.01/DHP-HÐÐÐ,2023 Dec).
文摘Analyzing physical activities through wearable devices is a promising research area for improving health assessment.This research focuses on the development of an affordable and real-time Human Activity Recognition(HAR)system designed to operate on low-performance microcontrollers.The system utilizes data from a bodyworn accelerometer to recognize and classify human activities,providing a cost-effective,easy-to-use,and highly accurate solution.A key challenge addressed in this study is the execution of efficient motion recognition within a resource-constrained environment.The system employs a Random Forest(RF)classifier,which outperforms Gradient Boosting Decision Trees(GBDT),Support Vector Machines(SVM),and K-Nearest Neighbors(KNN)in terms of accuracy and computational efficiency.The proposed features Average absolute deviation(AAD),Standard deviation(STD),Interquartile range(IQR),Range,and Root mean square(RMS).The research has conducted numerous experiments and comparisons to establish optimal parameters for ensuring system effectiveness,including setting a sampling frequency of 50 Hz and selecting an 8-s window size with a 40%overlap between windows.Validation was conducted on both the WISDM public dataset and a self-collected dataset,focusing on five fundamental daily activities:Standing,Sitting,Jogging,Walking,and Walking the stairs.The results demonstrated high recognition accuracy,with the system achieving 96.7%on the WISDM dataset and 97.13%on the collected dataset.This research confirms the feasibility of deploying HAR systems on low-performance microcontrollers and highlights the system’s potential applications in patient support,rehabilitation,and elderly care.
文摘Autophagy,a conserved cellular degradation process,is crucial for various cellular processes such as immune responses,inflammation,metabolic and oxidative stress adaptation,cell proliferation,development,and tissue repair and remodeling.Dysregulation of autophagy is suspected in numerous diseases,including cancer,neurodegenerative diseases,digestive disorders,metabolic syndromes,and infectious and inflammatory diseases.If autophagy is disrupted,for example,this can have serious consequences and lead to chronic inflammation and tissue damage,as occurs in diseases such as Chron's disease and ulcerative colitis.On the other hand,the influence of autophagy on the development and progression of cancer is not clear.Autophagy can both suppress and promote the progression and metastasis of cancer at various stages.From inflammatory bowel diseases to gastrointestinal cancer,researchers are discovering the intricate role of autophagy in maintaining gut health and its potential as a therapeutic target.Researchers should carefully consider the nature and progression of diseases such as cancer when trying to determine whether inhibiting or stimulating autophagy is likely to be beneficial.Multidisciplinary approaches that combine cutting-edge research with clinical expertise are key to unlocking the full therapeutic potential of autophagy in digestive diseases.
文摘At present,there are unharmonious factors existing in Chinese family education,which particular manifest in the means of family education.The Three Character Primer,as an epitome of the essence of Chinese traditional culture,can provide enlightenment on building a democratic and harmonious family education means.
文摘为探究中国铜期货市场价格波动的变化规律并以此预测其风险值,以沪铜期货高频价格数据为样本,综合考虑其收益率波动的聚集性、偏峰厚尾性与长记忆性,将广义已实现测度引入偏t分布假设下的Realized GARCH模型与拓展的Realized HAR GARCH模型中,并通过样本内拟合与样本外滚动预测,结合似然函数、VaR后验测试与损失函数MCS检验法综合比较了采用不同已实现测度的Realized GARCH以及Realized HAR GARCH模型在沪铜期货收益波动率估计和VaR预测上的效果。实证结果显示:对于沪铜期货市场而言,无论是波动率估计还是风险预测,广义已实现测度的引入显著地提升了Realized GARCH与Realized HAR GARCH模型的拟合效果与预测能力,其中基于日内损失RMAD与RES测度下的Realized HAR GARCH模型分别拥有最优的估计与预测表现。
