Background:Muscular strength is a powerful marker of current health status and robust predictor of age-related disease and disability.Handgrip strength(HGS)using isometric dynamometry is a convenient,feasible,and wide...Background:Muscular strength is a powerful marker of current health status and robust predictor of age-related disease and disability.Handgrip strength(HGS)using isometric dynamometry is a convenient,feasible,and widely used method of assessing muscular strength among people of all ages.While adult HGS norms have been published for many countries,no study has yet synthesized available data to produce international norms.The objective of this study was to generate international sex-and age-specific norms for absolute and body size-normalized HGS across the adult lifespan.Methods:Systematic searches were conducted in 6 databases/web search engines(MEDLINE,SPORTDiscus,Embase,Web of Science,CINAHL,and Google Scholar)up to December 1,2023.We included full-text peer-reviewed observational studies that reported normative HGS data for adults aged ≥20 years by sex and age.Pseudo data were generated using Monte Carlo simulation following harmonization for methodo-logical variation.Population-weighted Generalized Additive Models for Location,Scale,and Shape were used to develop sex-and age-specific norms for absolute HGS(kg)and HGS normalized by height(Ht,m)squared(i.e.,HGS/Ht^(2)in kg/m^(2)).Norms were tabulated as percentile values(5th to 95th)and visualized as smoothed percentile curves.Results:We included data from 100 unique observational studies representing 2,405,863 adults(51.9%female)aged 20 to 100+years from 69 countries and regions tested from the year 2000 onward.On average,absolute and normalized HGS values negligibly improved throughout early adulthood,peaked from age 3039 years(at 49.7 kg(males)and 29.7 kg(females)for absolute HGS or 16.3 kg/m^(2)(males)and 11.3 kg/m^(2)(females)for HGS/Ht^(2)),and declined afterwards.The age-related decline in HGS accelerated from middle to late adulthood and was slightly larger for males than for females during middle adulthood.Conclusion:This study provides the world’s largest and most geographically comprehensive international norms for adult HGS by sex and age.These norms have utility for global peer-comparisons,health screening,and surveillance.展开更多
Objective:While albumin and the weight-standardized hand grip strength(HGS/W)serve as valuable prognostic indicators for cancer patients,their correlation with the prognosis in frail cancer patients remains inadequate...Objective:While albumin and the weight-standardized hand grip strength(HGS/W)serve as valuable prognostic indicators for cancer patients,their correlation with the prognosis in frail cancer patients remains inadequately explored.This study aimed to investigate the prognostic importance of the albumin level and HGS/W in cancer patients with frailty and to further investigate their combined prognostic value.Moreover,this comprehensive evaluation aimed to facilitate timely intervention and treatment for frail patients.Methods:The research enrolled 5,794 cancer patients identified with frailty from a multicenter research database.The diagnosis of frailty was based on the FRAIL scale.An Albumin-HGS/W score was constructed by combining the albumin and HGS/W values.Cox proportional hazard regression was utilized to examine the association between the albumin level and HGS/W and patient outcomes.Results:Among these patients,2,543 were females and 3,251 were males,with a median age of 60.0 years.Optimal stratification based on patient survival revealed the ideal threshold for HGS/W to be 0.48 for males and 0.39 for females,and for albumin to be 38 for both sexes.The fully adjusted model revealed that higher Albumin-HGS/W scores were correlated with a poorer patient prognosis.Notably,an Albumin-HGS/W score of 2 was associated with a higher risk of mortality compared with a score of 0 in the total population(HR:1.813,95%CI:1.580-2.080,P<0.001).Conclusions:Low albumin or HGS/W values are associated with low survival in cancer patients with frailty.Elevated Albumin-HGS/W scores were linked to decreased survival rates in cancer patients with frailty.展开更多
Objective: To evaluate the prevalence of hand osteoarthritis (hOA) in a population with knee osteoarthritis (KOA) at baseline and one year following the administration of a multi-professional OA educational program co...Objective: To evaluate the prevalence of hand osteoarthritis (hOA) in a population with knee osteoarthritis (KOA) at baseline and one year following the administration of a multi-professional OA educational program correlating symptoms and changes in BMI with function questionnaires of the upper limbs and direct grip strength measurements. Design: Epidemiological study of the prevalence of hand OA in patients with knee osteoarthritis. The Stanford Health Assessment Questionnaire instruments (HAQ);Disabilities of the Arm, Shoulder and Hand* (DASH);grip strength;and finger pinch were utilized, and the upper limbs symptoms were verified at baseline and one year following the educational program. Results: The prevalence of hOA was 23.7% at baseline and 47.4% at one year (incidence of 31.8% per year). The HAQ indicated that patients who did not alter or increased their BMI experienced worsened global strength, whereas patients who reduced BMI improved global strength (p = 0.041). Patients with higher initial BMIs experienced less improvement in the HAQ (r = -0.148, p = 0.041). The DASH results improved, but the right and left tripod grip worsened in all patients, irrespective of BMI change (p < 0.05) or symptoms at baseline and reassessment (p < 0.05). Pinch strength (right and left tripod and left pulp-pulp) was higher in patients without symptoms at baseline (p = 0.048, p = 0.045 and 0.033, respectively). Conclusions: The prevalence of hand OA increased for patients with OA undergoing an educational program irrespective of improved upper function and regardless of BMI change. Patients who decreased their BMI improved their global strength.展开更多
Background: Since the minimum grip span of a standard Smedley hand dynamometer is 4 cm, the handgrip strength (HGS) value at a less than 4 cm grip span has not been reported. Objective: The present study examined the ...Background: Since the minimum grip span of a standard Smedley hand dynamometer is 4 cm, the handgrip strength (HGS) value at a less than 4 cm grip span has not been reported. Objective: The present study examined the impact of grip span on handgrip strength (HGS) in young children using a dynamometer ranging from 2 to 4.5 cm of grip span. Methods: A total of 93 (39 girls and 54 boys) children were recruited from a local kindergarten with the cooperation of their parents. Each participant performed one test trial and then five maximal trials using different grip spans (2.0, 3.0, 3.5, 4.0, and 4.5 cm) in random order and allowing a 1-minute rest between measures. Results: There was a statistically significant difference in HGS depending on which grip span was used, χ<sup>2</sup>(4) = 211.5 (p Conclusion: Our results recommended that the target grip span for measuring maximal HGS in young children is about 4 cm (4 ± 0.5 cm).展开更多
BACKGROUND： Rheumatoid arthritis（RA） is a systemic inflammatory disease characterized by functional disability and pain. Although acupuncture is widely used, until now Western acupuncture studies on RA have not sho...BACKGROUND： Rheumatoid arthritis（RA） is a systemic inflammatory disease characterized by functional disability and pain. Although acupuncture is widely used, until now Western acupuncture studies on RA have not shown conclusive positive results. Acupuncture is regarded as a reflex therapy that has effects on the human autonomic nervous system. By establishing a traditional Chinese medicine（TCM） diagnosis first, the practitioner is able to choose acupoints according to the state of each individual patient.METHODS/DESIGN： We are interested if acupuncture, using a classical diagnostic procedure to allocate acupoints to the patient according to the Shang Han Lun theory, can be effective in relieving pain, improving hand function and increasing health-related quality of life in RA.The authors intend to harmonize TCM diagnosis according to clinical and genetic profiles. Patients with the TCM diagnosis of a so-called Turning Point syndrome will be followed up in a randomized, prospective, double-blind, placebo-controlled, multicenter and three-armed parallel-group study with a standardized treatment in order to optimize potential therapeutic effects of acupuncture on pain, strength and muscle function of patients with RA as well as the influence on inflammation and quality of life.DISCUSSION： The findings of this study will provide important clinical information about the feasibility and efficacy of acupuncture treatment for RA patients. In addition, it will explore the feasibility of further acupuncture research.TRIAL REGISTRATION NUMBER： Clinical Trials.gov Identifier NCT02553005.展开更多
Aim: Assess upper and lower limb functions in elderly with heart failure (HF) and evaluate its relation to HF severity. Methods: Handgrip strength (HGS) in kilograms (kgs.) of both hands using handle mechanical dynamo...Aim: Assess upper and lower limb functions in elderly with heart failure (HF) and evaluate its relation to HF severity. Methods: Handgrip strength (HGS) in kilograms (kgs.) of both hands using handle mechanical dynamometer and counting the repetitions (rep.) of stand and sit on a chair during 30 seconds [the 30 seconds chair-stand test (CST)] were used in 71 elderly (≥65 years old) patients with clinically stable HF and other matched 32 healthy elderly as a control. HF was diagnosed clinically, by plasma B-Type natriuretic peptide (BNP) and by echocardiography. The New York Heart Association (NYHA) functional classification of HF was used to obtain two groups: NYHA class I-II (33 patients), and NYHA class III (38 patients). Results: Showed significant decrease in both HGS and CST score in all HF patients (9.7 ± 4.4 kgs., 8.8 ± 3.1 rep., respectively) compared to controls (77.8 ± 11 kgs., 13.5 ± 1.1 rep., respectively, p Conclusion: Upper and lower limb muscles?strength, assessed by two easy andinexpensive tests (HGS and CST), may reflect clinical severity of HF in elderly patients who cannot usually perform exercise tests. Its prognostic value requires further follow-up studies to verify.展开更多
Background: Test-retest strength reliability of the Electronic Push/Pull Dynamometer (EPPD) in the measurement of the extensor and flexor muscles on a new constructed chair. The objective of the study was to assess re...Background: Test-retest strength reliability of the Electronic Push/Pull Dynamometer (EPPD) in the measurement of the extensor and flexor muscles on a new constructed chair. The objective of the study was to assess reliability of Electronic Push/Pull Dynamometer in the measurement of the knee flexion and extension at 90° and 60° on a new constructed chair. The aims of the author: To assess reliability of Electronic Push/Pull Dynamometer in the measurement of the knee flexion and extension at 90° and 60° on a new constructed chair. Design: A test-retest reliability study. Subjects: One hundred healthy students male and female (mean age, 21y). Methods: Maximum isometric strength of the quadriceps and hamstring muscle groups was measured using the EPPD were recorded at 60° and 90° for 3 trials on 2 occasions. Reliability was assessed with the Intraclass correlation coefficient (ICC), mean and standard deviation (SD) of measurements, and smallest real differences were calculated for the maximum and for the mean and work of the 3 repetitions. Results: Mean strength ranged from 50.44 kg for knee flexion to 55.76 kg for knee extension 50.44 kg to 61.98 kg at 90° hip flexion. Test-retest reliability Intraclass correlation coefficients (ICCs) ranged from 0.85 to 0.99. ICCs for test-retest reliability ranged from 0.780 to 0.998. Conclusions: The results of the reliability study indicate that the EPPD in reliable dynamometer to use in determining lower limb muscle force production. It can be used to measure disease progression and to evaluate changes in knee extension and flexion strength at the individual patient level.展开更多
BACKGROUND Morphomics,a computed tomography-based body composition assessment,helps predicting esophageal cancer outcomes,but its link to bioelectrical impedance analysis(BIA)and functional assessments such as hand gr...BACKGROUND Morphomics,a computed tomography-based body composition assessment,helps predicting esophageal cancer outcomes,but its link to bioelectrical impedance analysis(BIA)and functional assessments such as hand grip strength(HGS)and cardiopulmonary exercise testing(CPET)remains unclear.AIM To investigate correlations between morphomics and BIA,HGS,CPET,and assess its ability to predict low cardiorespiratory fitness(CRF).METHODS Fifty esophageal cancer patients underwent multi-level morphomics,BIA,HGS,and CPET.Correlations were analyzed using heatmaps and scatter plots,and logistic regression assessed morphomic predictive value for low CRF.RESULTS T11 is the only level with complete morphomic data,making it the most applicable.To ensure reliability,T11 and its adjacent levels,T10-12,were included in the subsequent analysis.Dorsal muscle group volume from T10-12 morphomics all correlated positively with BIA muscle components(r=0.56-0.68,all P<0.001),HGS(r=0.4-0.48,all P<0.001),and CPET variables(r=0.43-0.51,all P<0.001).Subcutaneous fat area and visceral fat area from morphomics correlated with body fat percentage(r=0.58-0.67,all P<0.001)and negatively with CPET parameters(r=-0.33 to-0.52,all P<0.05).Morphomics also showed potential in identifying low CRF,with an area under the receiver operating characteristic curve of 0.778.CONCLUSION T11 morphomics shows strong correlation with BIA,HGS,and CPET,and may serve as a practical tool for preoperative risk assessment in esophageal cancer patients.展开更多
目的:根据手外伤后手功能障碍的特点,基于虚拟现实技术研制出一种增强手部肌力和协调性的手功能康复训练系统。方法:通过贴片式压力传感器实时采集患手的力学信息,将其输入到虚拟现实环境中驱动虚拟环境的运行,该系统能够智能设置虚拟...目的:根据手外伤后手功能障碍的特点,基于虚拟现实技术研制出一种增强手部肌力和协调性的手功能康复训练系统。方法:通过贴片式压力传感器实时采集患手的力学信息,将其输入到虚拟现实环境中驱动虚拟环境的运行,该系统能够智能设置虚拟环境中执行任务的难度,根据采集到的力学信息作出相应的康复评价。本文从总体构思,系统的组成和功能设计,系统实现所采用的力传感器模块、采集模块、虚拟现实模块和评估模块开发等方面进行介绍,并进行了初步的临床对照试验。结果:研制出基于虚拟现实技术的手功能康复系统;通过2周的临床试验,试验组在侧捏力(0.64±0.75N vs 0.09±0.21N)、握力(2.14±1.57N vs 0.81±1.00N)、ADL评分(3.44±2.45 vs 0.67±2.82)方面改善均优于对照组(P<0.05)。结论:该系统具有成本低、结构简单、易于维护、安全性高等特点,有助于推动虚拟现实技术在手功能康复治疗领域中的应用。展开更多
基金supported by European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska Curie grant agreement(No.101028929)BJFis supported by National Heart Foundation of Australia Postdoc-toral Fellowship(No.106588)+1 种基金BG is supported by Australian Government Research Training Program ScholarshipDPLis supported by Clive Kearon Award,McMaster University.Additional funding information can be found in Supplemen-tary Funding.
文摘Background:Muscular strength is a powerful marker of current health status and robust predictor of age-related disease and disability.Handgrip strength(HGS)using isometric dynamometry is a convenient,feasible,and widely used method of assessing muscular strength among people of all ages.While adult HGS norms have been published for many countries,no study has yet synthesized available data to produce international norms.The objective of this study was to generate international sex-and age-specific norms for absolute and body size-normalized HGS across the adult lifespan.Methods:Systematic searches were conducted in 6 databases/web search engines(MEDLINE,SPORTDiscus,Embase,Web of Science,CINAHL,and Google Scholar)up to December 1,2023.We included full-text peer-reviewed observational studies that reported normative HGS data for adults aged ≥20 years by sex and age.Pseudo data were generated using Monte Carlo simulation following harmonization for methodo-logical variation.Population-weighted Generalized Additive Models for Location,Scale,and Shape were used to develop sex-and age-specific norms for absolute HGS(kg)and HGS normalized by height(Ht,m)squared(i.e.,HGS/Ht^(2)in kg/m^(2)).Norms were tabulated as percentile values(5th to 95th)and visualized as smoothed percentile curves.Results:We included data from 100 unique observational studies representing 2,405,863 adults(51.9%female)aged 20 to 100+years from 69 countries and regions tested from the year 2000 onward.On average,absolute and normalized HGS values negligibly improved throughout early adulthood,peaked from age 3039 years(at 49.7 kg(males)and 29.7 kg(females)for absolute HGS or 16.3 kg/m^(2)(males)and 11.3 kg/m^(2)(females)for HGS/Ht^(2)),and declined afterwards.The age-related decline in HGS accelerated from middle to late adulthood and was slightly larger for males than for females during middle adulthood.Conclusion:This study provides the world’s largest and most geographically comprehensive international norms for adult HGS by sex and age.These norms have utility for global peer-comparisons,health screening,and surveillance.
基金supported by a Henan Province Science and Technology Research Project(No.252102311033)the National Key Research and Development Program(No.2022YFC2009600 and No.2022YFC2009601).
文摘Objective:While albumin and the weight-standardized hand grip strength(HGS/W)serve as valuable prognostic indicators for cancer patients,their correlation with the prognosis in frail cancer patients remains inadequately explored.This study aimed to investigate the prognostic importance of the albumin level and HGS/W in cancer patients with frailty and to further investigate their combined prognostic value.Moreover,this comprehensive evaluation aimed to facilitate timely intervention and treatment for frail patients.Methods:The research enrolled 5,794 cancer patients identified with frailty from a multicenter research database.The diagnosis of frailty was based on the FRAIL scale.An Albumin-HGS/W score was constructed by combining the albumin and HGS/W values.Cox proportional hazard regression was utilized to examine the association between the albumin level and HGS/W and patient outcomes.Results:Among these patients,2,543 were females and 3,251 were males,with a median age of 60.0 years.Optimal stratification based on patient survival revealed the ideal threshold for HGS/W to be 0.48 for males and 0.39 for females,and for albumin to be 38 for both sexes.The fully adjusted model revealed that higher Albumin-HGS/W scores were correlated with a poorer patient prognosis.Notably,an Albumin-HGS/W score of 2 was associated with a higher risk of mortality compared with a score of 0 in the total population(HR:1.813,95%CI:1.580-2.080,P<0.001).Conclusions:Low albumin or HGS/W values are associated with low survival in cancer patients with frailty.Elevated Albumin-HGS/W scores were linked to decreased survival rates in cancer patients with frailty.
文摘Objective: To evaluate the prevalence of hand osteoarthritis (hOA) in a population with knee osteoarthritis (KOA) at baseline and one year following the administration of a multi-professional OA educational program correlating symptoms and changes in BMI with function questionnaires of the upper limbs and direct grip strength measurements. Design: Epidemiological study of the prevalence of hand OA in patients with knee osteoarthritis. The Stanford Health Assessment Questionnaire instruments (HAQ);Disabilities of the Arm, Shoulder and Hand* (DASH);grip strength;and finger pinch were utilized, and the upper limbs symptoms were verified at baseline and one year following the educational program. Results: The prevalence of hOA was 23.7% at baseline and 47.4% at one year (incidence of 31.8% per year). The HAQ indicated that patients who did not alter or increased their BMI experienced worsened global strength, whereas patients who reduced BMI improved global strength (p = 0.041). Patients with higher initial BMIs experienced less improvement in the HAQ (r = -0.148, p = 0.041). The DASH results improved, but the right and left tripod grip worsened in all patients, irrespective of BMI change (p < 0.05) or symptoms at baseline and reassessment (p < 0.05). Pinch strength (right and left tripod and left pulp-pulp) was higher in patients without symptoms at baseline (p = 0.048, p = 0.045 and 0.033, respectively). Conclusions: The prevalence of hand OA increased for patients with OA undergoing an educational program irrespective of improved upper function and regardless of BMI change. Patients who decreased their BMI improved their global strength.
文摘Background: Since the minimum grip span of a standard Smedley hand dynamometer is 4 cm, the handgrip strength (HGS) value at a less than 4 cm grip span has not been reported. Objective: The present study examined the impact of grip span on handgrip strength (HGS) in young children using a dynamometer ranging from 2 to 4.5 cm of grip span. Methods: A total of 93 (39 girls and 54 boys) children were recruited from a local kindergarten with the cooperation of their parents. Each participant performed one test trial and then five maximal trials using different grip spans (2.0, 3.0, 3.5, 4.0, and 4.5 cm) in random order and allowing a 1-minute rest between measures. Results: There was a statistically significant difference in HGS depending on which grip span was used, χ<sup>2</sup>(4) = 211.5 (p Conclusion: Our results recommended that the target grip span for measuring maximal HGS in young children is about 4 cm (4 ± 0.5 cm).
文摘BACKGROUND： Rheumatoid arthritis（RA） is a systemic inflammatory disease characterized by functional disability and pain. Although acupuncture is widely used, until now Western acupuncture studies on RA have not shown conclusive positive results. Acupuncture is regarded as a reflex therapy that has effects on the human autonomic nervous system. By establishing a traditional Chinese medicine（TCM） diagnosis first, the practitioner is able to choose acupoints according to the state of each individual patient.METHODS/DESIGN： We are interested if acupuncture, using a classical diagnostic procedure to allocate acupoints to the patient according to the Shang Han Lun theory, can be effective in relieving pain, improving hand function and increasing health-related quality of life in RA.The authors intend to harmonize TCM diagnosis according to clinical and genetic profiles. Patients with the TCM diagnosis of a so-called Turning Point syndrome will be followed up in a randomized, prospective, double-blind, placebo-controlled, multicenter and three-armed parallel-group study with a standardized treatment in order to optimize potential therapeutic effects of acupuncture on pain, strength and muscle function of patients with RA as well as the influence on inflammation and quality of life.DISCUSSION： The findings of this study will provide important clinical information about the feasibility and efficacy of acupuncture treatment for RA patients. In addition, it will explore the feasibility of further acupuncture research.TRIAL REGISTRATION NUMBER： Clinical Trials.gov Identifier NCT02553005.
文摘Aim: Assess upper and lower limb functions in elderly with heart failure (HF) and evaluate its relation to HF severity. Methods: Handgrip strength (HGS) in kilograms (kgs.) of both hands using handle mechanical dynamometer and counting the repetitions (rep.) of stand and sit on a chair during 30 seconds [the 30 seconds chair-stand test (CST)] were used in 71 elderly (≥65 years old) patients with clinically stable HF and other matched 32 healthy elderly as a control. HF was diagnosed clinically, by plasma B-Type natriuretic peptide (BNP) and by echocardiography. The New York Heart Association (NYHA) functional classification of HF was used to obtain two groups: NYHA class I-II (33 patients), and NYHA class III (38 patients). Results: Showed significant decrease in both HGS and CST score in all HF patients (9.7 ± 4.4 kgs., 8.8 ± 3.1 rep., respectively) compared to controls (77.8 ± 11 kgs., 13.5 ± 1.1 rep., respectively, p Conclusion: Upper and lower limb muscles?strength, assessed by two easy andinexpensive tests (HGS and CST), may reflect clinical severity of HF in elderly patients who cannot usually perform exercise tests. Its prognostic value requires further follow-up studies to verify.
文摘Background: Test-retest strength reliability of the Electronic Push/Pull Dynamometer (EPPD) in the measurement of the extensor and flexor muscles on a new constructed chair. The objective of the study was to assess reliability of Electronic Push/Pull Dynamometer in the measurement of the knee flexion and extension at 90° and 60° on a new constructed chair. The aims of the author: To assess reliability of Electronic Push/Pull Dynamometer in the measurement of the knee flexion and extension at 90° and 60° on a new constructed chair. Design: A test-retest reliability study. Subjects: One hundred healthy students male and female (mean age, 21y). Methods: Maximum isometric strength of the quadriceps and hamstring muscle groups was measured using the EPPD were recorded at 60° and 90° for 3 trials on 2 occasions. Reliability was assessed with the Intraclass correlation coefficient (ICC), mean and standard deviation (SD) of measurements, and smallest real differences were calculated for the maximum and for the mean and work of the 3 repetitions. Results: Mean strength ranged from 50.44 kg for knee flexion to 55.76 kg for knee extension 50.44 kg to 61.98 kg at 90° hip flexion. Test-retest reliability Intraclass correlation coefficients (ICCs) ranged from 0.85 to 0.99. ICCs for test-retest reliability ranged from 0.780 to 0.998. Conclusions: The results of the reliability study indicate that the EPPD in reliable dynamometer to use in determining lower limb muscle force production. It can be used to measure disease progression and to evaluate changes in knee extension and flexion strength at the individual patient level.
基金Supported by Chang Gung Memorial Hospital,Taiwan,No.CMRPG3N1171,No.CMRPG3N1172,No.CORPVVN0071,No.CMRPVVK0111-3 and No.CMRPVVL0121-3National Science and Technology Council,Taiwan,No.MOST 114-2314-B-182A-066-.
文摘BACKGROUND Morphomics,a computed tomography-based body composition assessment,helps predicting esophageal cancer outcomes,but its link to bioelectrical impedance analysis(BIA)and functional assessments such as hand grip strength(HGS)and cardiopulmonary exercise testing(CPET)remains unclear.AIM To investigate correlations between morphomics and BIA,HGS,CPET,and assess its ability to predict low cardiorespiratory fitness(CRF).METHODS Fifty esophageal cancer patients underwent multi-level morphomics,BIA,HGS,and CPET.Correlations were analyzed using heatmaps and scatter plots,and logistic regression assessed morphomic predictive value for low CRF.RESULTS T11 is the only level with complete morphomic data,making it the most applicable.To ensure reliability,T11 and its adjacent levels,T10-12,were included in the subsequent analysis.Dorsal muscle group volume from T10-12 morphomics all correlated positively with BIA muscle components(r=0.56-0.68,all P<0.001),HGS(r=0.4-0.48,all P<0.001),and CPET variables(r=0.43-0.51,all P<0.001).Subcutaneous fat area and visceral fat area from morphomics correlated with body fat percentage(r=0.58-0.67,all P<0.001)and negatively with CPET parameters(r=-0.33 to-0.52,all P<0.05).Morphomics also showed potential in identifying low CRF,with an area under the receiver operating characteristic curve of 0.778.CONCLUSION T11 morphomics shows strong correlation with BIA,HGS,and CPET,and may serve as a practical tool for preoperative risk assessment in esophageal cancer patients.
文摘目的:根据手外伤后手功能障碍的特点,基于虚拟现实技术研制出一种增强手部肌力和协调性的手功能康复训练系统。方法:通过贴片式压力传感器实时采集患手的力学信息,将其输入到虚拟现实环境中驱动虚拟环境的运行,该系统能够智能设置虚拟环境中执行任务的难度,根据采集到的力学信息作出相应的康复评价。本文从总体构思,系统的组成和功能设计,系统实现所采用的力传感器模块、采集模块、虚拟现实模块和评估模块开发等方面进行介绍,并进行了初步的临床对照试验。结果:研制出基于虚拟现实技术的手功能康复系统;通过2周的临床试验,试验组在侧捏力(0.64±0.75N vs 0.09±0.21N)、握力(2.14±1.57N vs 0.81±1.00N)、ADL评分(3.44±2.45 vs 0.67±2.82)方面改善均优于对照组(P<0.05)。结论:该系统具有成本低、结构简单、易于维护、安全性高等特点,有助于推动虚拟现实技术在手功能康复治疗领域中的应用。
