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重度子痫前期患者妊娠末期24-hUP、HCT-ALB、BNP联合预测产后高血压的效能分析
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作者 杨晓巍 汪燕 +1 位作者 曾沥琼 江雪莲 《昆明医科大学学报》 2025年第2期151-157,共7页
目的探讨重度子痫前期患者妊娠末期24 h尿蛋白定量(24-hUP)、红细胞压积与血浆白蛋白差值(HCT-ALB)、脑钠肽(BNP)联合预测产后高血压的效能。方法采用整群抽样法,回顾性选取重庆医科大学附属大学城医院2018年1月—2022年12月540例重度... 目的探讨重度子痫前期患者妊娠末期24 h尿蛋白定量(24-hUP)、红细胞压积与血浆白蛋白差值(HCT-ALB)、脑钠肽(BNP)联合预测产后高血压的效能。方法采用整群抽样法,回顾性选取重庆医科大学附属大学城医院2018年1月—2022年12月540例重度子痫前期患者,根据是否发生产后高血压分为高血压组(n=98)与非高血压组(n=442)。比较两组临床资料[年龄、体质量指数(BMI)、产妇类型、流产史、高血压家族史、吸烟史、总胆固醇(TC)、甘油三酯(TG)、空腹血糖(FBG)、收缩压(SBP)、舒张压(DBP)]及妊娠末期24-hUP、HCT-ALB、BNP水平,分析妊娠末期24-hUP、HCT-ALB、BNP水平对产后高血压的预测价值。结果高血压组BMI、高血压家族史、TC、TG、FBG、SBP、DBP水平高于非高血压组[(25.63±1.37)kg/m2 vs(23.05±1.23)kg/m2,70.41%vs 30.54%,(5.32±1.14)mmol/L vs(3.91±0.95)mmol/L,(3.48±0.82)mmol/L vs(1.66±0.43)mmol/L,(7.24±1.60)mmol/L vs(4.83±1.22)mmol/L,(148.27±13.29)mmHg vs(127.65±10.71)mmHg,(92.36±5.17)mmHg vs(84.20±4.35)mmHg],差异有统计学意义(P<0.05);高血压组妊娠末期24-hUP、HCT、HCT-ALB、BNP水平高于非高血压组[(7.82±2.18)g/24 h vs(6.15±1.26)g/24 h,(34.22±3.15)%vs(32.80±1.77)%,(6.19±2.01)vs(3.46±0.90),(646.43±170.59)pg/mL vs(523.81±134.62)pg/mL],ALB水平低于非高血压组[(28.03±1.13)g/L vs(29.34±1.44)g/L],差异有统计学意义(P<0.05);妊娠末期24-hUP、HCT、HCTALB、BNP与SBP、DBP呈正相关,ALB与之呈负相关,差异有统计学意义(P<0.05);妊娠末期24-hUP、HCT-ALB、BNP是产后高血压的独立危险因素,各指标联合预测产后高血压的AUC为0.930(95%CI:0.905~0.950),约登指数为0.719,敏感度为85.71%,特异度为86.20%,且联合预测的AUC明显大于三者单独预测,差异有统计学意义(P<0.05)。结论妊娠末期24-hUP、HCT-ALB、BNP是产后高血压的独立危险因素,联合预测效能明显优于单一指标,可作为临床预测重度子痫前期患者是否发生产后高血压的优选方式。 展开更多
关键词 重度子痫前期 妊娠末期 24 h尿蛋白 红细胞压积与血浆白蛋白差值 脑钠肽 产后高血压 预测
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Unruh Metric Tensor HUP via Planckian Space-Time Compared to HUP Based Complexity of Measured System Results to Obtain Inflaton Potential Magnitude
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作者 Andrew Walcott Beckwith 《Journal of High Energy Physics, Gravitation and Cosmology》 CAS 2024年第4期1628-1642,共15页
First of all, we restate a proof of a highly localized special case of a metric tensor uncertainty principle first written up by Unruh. Unruh did not use the Roberson-Walker geometry which we do, and it so happens tha... First of all, we restate a proof of a highly localized special case of a metric tensor uncertainty principle first written up by Unruh. Unruh did not use the Roberson-Walker geometry which we do, and it so happens that the dominant metric tensor we will be examining, is variation in δgtt. The metric tensor variations given by δgrr, δgθθand δgϕϕare negligible, as compared to the variation δgtt. Afterwards, what is referred to by Barbour as emergent duration of time δtis from the Heisenberg Uncertainty principle (HUP) applied to δgttin such a way as to be compared with ΔxΔp≥ℏ2+γ˜∂C∂Vwith V here a volume spatial term and γ˜a complexification strength term and ∂C∂Vinfluence of complexity of physical system being measured in order to obtain a parameterized value for the initial value of an inflaton which we call V0. 展开更多
关键词 Massive Gravitons Heisenberg Uncertainty Principle (hup)
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BFS-HUP模型在潼关站洪水概率预报中的应用 被引量:8
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作者 蒋晓蕾 梁忠民 +2 位作者 王春青 刘晓伟 刘龙庆 《人民黄河》 CAS 北大核心 2015年第7期13-15,21,共4页
采用马斯京根演算法作为确定性预报模型,并选用贝叶斯预报系统(BFS)的水文不确定性处理器(HUP)作为概率预报模型,获得预报变量的概率分布,实现黄河潼关站洪水的概率预报。将预报变量概率分布的中位数作为定值预报与确定性预报进行对比,... 采用马斯京根演算法作为确定性预报模型,并选用贝叶斯预报系统(BFS)的水文不确定性处理器(HUP)作为概率预报模型,获得预报变量的概率分布,实现黄河潼关站洪水的概率预报。将预报变量概率分布的中位数作为定值预报与确定性预报进行对比,发现预报精度有所提高,表明贝叶斯模型的预报校正能力较强。通过设定不同确定性预报精度的情景方案,探讨了确定性预报精度对概率预报可靠度的影响。结果表明,随着确定性预报精度的提高,概率预报区间宽度和离散度均有所减小;HUP洪水概率预报的可靠度对确定性预报的偶然性误差比较敏感,对系统偏差相对不敏感。 展开更多
关键词 贝叶斯预报系统(BFS) 水文不确定性处理器(hup) 洪水概率预报 潼关
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浑球红细菌Rhodobacter sphaeroides吸氨酶(hup)基因簇的分离与鉴定
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作者 梁建光 吴永强 +2 位作者 宋鸿遇 AnnetteColbeau PauletteM.Vignais 《植物生理学报(0257-4829)》 CSCD 1998年第3期233-239,共7页
以Rhodobactercapsulatus的hopS’L基因DNA片段为探针,通过Southem杂交,从构建的Rhodobactersphaeroides601基因库中调取hup基因。阳性克隆Cosmid1可与Hup突变株JP91(HupS-)、RCC8(HupR-)以及BSE8(HupT-)互补,而Cosmid3和Cosm... 以Rhodobactercapsulatus的hopS’L基因DNA片段为探针,通过Southem杂交,从构建的Rhodobactersphaeroides601基因库中调取hup基因。阳性克隆Cosmid1可与Hup突变株JP91(HupS-)、RCC8(HupR-)以及BSE8(HupT-)互补,而Cosmid3和Cosmid9只能与BSE8互补;试验所产生的接合转移子均恢复了吸氢酶的活性和自养生长能力、将Cosmidl的3.5kbPstⅠ和4.5kbBamHⅠ片段分别亚克隆到pWY11和pWY10中。pWY11和pWY10的部分DNA序列与R.capsulatus中的相关基因具有很高的同源性,从而证明了所得到的Cosmid1确实含有R.sphaeroides的基因簇。 展开更多
关键词 浑球红细菌 吸氢酶 基因簇 hup基因
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含吸氢酶基因(hup)嵌合质粒的构建和吸氢酶活性在阴沟肠杆菌中的表达 被引量:6
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作者 吴永强 朱美珍 +2 位作者 梁建光 华征 宋鸿遇 《植物生理学报(0257-4829)》 CSCD 1996年第3期209-217,共9页
以质粒pRK404为载体亚克隆含大豆根瘤菌吸氢酶结构基因(hup)的片段,构建成嵌合质粒pHR11、pHR4和pHR10。通过三亲本杂交将这些嵌合质粒导入无吸氢活性的Rhodobactersphaeroides241... 以质粒pRK404为载体亚克隆含大豆根瘤菌吸氢酶结构基因(hup)的片段,构建成嵌合质粒pHR11、pHR4和pHR10。通过三亲本杂交将这些嵌合质粒导入无吸氢活性的Rhodobactersphaeroides241菌株(Hup-),均获得Hup+的接合子。利用启动子检测质粒pMP220证明,在hup对结构基因上游1.2kb内存在hup启动基因片段。以pRK2013为助质粒可将pHR11导入Enterobactercloacae和Klebsiellaoxytoca等土壤固氮菌株。本文以接合子E.cloacaeEH1113为例,通过对基因组DNASouthern杂交分析证明,嵌合质粒pHR11在EH1113中稳定贮存和复制。H2诱导接合子EH1113吸氢酶活性高表达,吸氢活性与放氢活性比值约为对照的两倍。当以延胡索酸为电子受体时,吸氢酶的吸氢作用支持菌株固氮酶活性的提高。 展开更多
关键词 固氮细菌 吸氢酶基因 南粒 吸氢酶 阴沟肠杆菌
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紫云英根瘤菌Hup°菌株吸氢与固氮
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作者 孙金华 陈秉俭 +2 位作者 郁宝麟 杨玉锁 宋鸿遇 《植物生理学报(0257-4829)》 CSCD 1991年第3期290-294,共5页
紫云英根瘤菌109菌株经NTG诱变后,选出1027,1247,1439,1675 4株菌株,其生长比野生型109菌株快,而其吸氢活性对碳底物不敏感或部分敏感,称为Hup°菌株。菌株1675和1439形成的根瘤其吸氢前的滞后时间缩短,表明内源抑制吸氢的效应缓解... 紫云英根瘤菌109菌株经NTG诱变后,选出1027,1247,1439,1675 4株菌株,其生长比野生型109菌株快,而其吸氢活性对碳底物不敏感或部分敏感,称为Hup°菌株。菌株1675和1439形成的根瘤其吸氢前的滞后时间缩短,表明内源抑制吸氢的效应缓解。经回接,1675菌株的Hup°性状较1439菌株稳定。由根瘤内分离回收的1675-1和1675-32两菌株,其共生体的吸氢与固氮活性均比菌株109高,其根瘤的耗氧量比109根瘤低,说明1675菌株有利于根瘤累积碳底物。 展开更多
关键词 紫云英 根瘤菌 hup^c菌株 吸氢
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The Transition from Pre-Octonionic to Octonionic Gravity and How It May Be Pertinent to a Re-Do of the HUP for Metric Tensors 被引量:1
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作者 Andrew Walcott Beckwith 《Journal of High Energy Physics, Gravitation and Cosmology》 2017年第4期727-753,共27页
The quantum gravity problem that the notion of a quantum state, representing the structure of space-time at some instant, and the notion of the evolution of the state, does not get traction, since there are no real “... The quantum gravity problem that the notion of a quantum state, representing the structure of space-time at some instant, and the notion of the evolution of the state, does not get traction, since there are no real “instants”, is avoided by having initial Octonionic geometry embedded in a larger, nonlinear “pilot model” (semi classical) embedding structure. The Penrose suggestion of recycled space time avoiding a “big crunch” is picked as the embedding structure, so as to avoid the “instants” of time issue. Getting Octionic gravity as embedded in a larger, Pilot theory embedding structure may restore Quantum Gravity to its rightful place in early cosmology without the complication of then afterwards “Schrodinger equation” states of the universe, and the transformation of Octonionic gravity to existing space-time is explored via its possible linkage to a new version of the HUP involving metric tensors. We conclude with how specific properties of Octonion numbers algebra influence the structure and behavior of the early-cosmology model. This last point is raised in Section 14, and is akin to a phase transition from Pre-Octonionic geometry, in pre-Planckian space-time, to Octonionic geometry in Planckian space-time. A simple phase transition is alluded to;making this clear is as simple as realizing that Pre-Octonionic is for Pre-Planckian Space-time and Octonionic is for Planckian Space-time. We state that the Standard Model of physics occurs during Planckian Space-time. We also argue that the Standard Model does not apply to Pre Planckian Space-time. This is commensurate with the Octonion number system NOT applying in pre-Planckian space-time, but applying in Plankian space-time. And the last line of Equation (54) gives a minimum time step in pre-Planckian space-time when we do NOT have the Standard Model of physics, or Octonionic Geometry. 展开更多
关键词 Octonionic Geometry CYCLIC CONFORMAL COSMOLOGY (Penrose) Modified hup
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Reconsidering “Does the Sum Rule Hold at the Big Bang?” with Pre Planckian HUP, and Division Algebras 被引量:1
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作者 Andrew W. Beckwith 《Journal of High Energy Physics, Gravitation and Cosmology》 2017年第4期539-557,共19页
In 2012, the author submitted an article to the Prespacetime Journal based upon the premise of inquiry as to the alleged vanishing of disjoint open sets contributing to quantum vector measures no longer working, i.e. ... In 2012, the author submitted an article to the Prespacetime Journal based upon the premise of inquiry as to the alleged vanishing of disjoint open sets contributing to quantum vector measures no longer working, i.e. the solution in 2012 was that the author stated that quantum measures in 4 dimensions would not work, mandating, if measure theory were used, imbedding in higher dimensions was necessary for a singularity. The idea was to use the methodology of String Theory as to come up with a way out of the impasse if higher dimensions do not exist. We revisit this question, taking into account a derived HUP, for metric tensors if we look at Pre-Planckian space-time introducing a pre-quantum mechanical HUP which may be a way to ascertain a solution not mandating higher dimensions, as well as introducing cautions as to what will disrupt the offered solution. Note that first, measurable spaces allow disjoint sets. Also, that smooth relations alone do not define separability or admit sets Planck’s length, if it exists, is a natural way to get about the “bad effects” of a cosmic singularity at the beginning of space-time evolution, but if a development is to be believed, namely by Stoica in the article, about removing the cosmic singularity as a breakdown point in relativity, there is nothing which forbids space-time from collapsing to a point. Without the use of a Pre Planckian HUP, for metric tensors, the quantum measures in four dimensions break down. We try to ascertain if a Pre Planckian HUP is sufficient to avoid this pathology and also look at if division algebras which can link Octonionic geometry and E8, to Quark spinors, in the standard model and add sufficient definition to the standard model are necessary and sufficient conditions for a metric tensor HUP which may remove this breakdown of the sum rule in the onset of the “Big Bang”. 展开更多
关键词 Quantum Measures Spatial DIFFEOMORPHISM Cylinder SETS Caratheodary-Hahn-Huvanek Theorem Big Bang Singularity Causal SETS Modified PRE Planckian HEISENBERG Uncertainty Principle hup Division ALGEBRAS
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How 5 Dimensions May Fix a Deterministic Background Spatially as to Be Inserted for HUP in 3 + 1 Dimensions, and Its Relevance to the Early Universe 被引量:1
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作者 Andrew Walcott Beckwith 《Journal of High Energy Physics, Gravitation and Cosmology》 CAS 2023年第1期1-6,共6页
We will first of all reference a value of momentum, in the early universe. This is for 3 + 1 dimensions and is important since Wesson has an integration of this momentum with regards to a 5 dimensional parameter inclu... We will first of all reference a value of momentum, in the early universe. This is for 3 + 1 dimensions and is important since Wesson has an integration of this momentum with regards to a 5 dimensional parameter included in an integration of momentum over space which equals a ration of L divided by small l (length) and all these times a constant. The ratio of L over small l is a way of making deterministic inputs from 5 dimensions into the 3 + 1 dimensional HUP. In doing so, we come up with a very small radial component for reasons which due to an argument from Wesson is a way to deterministically fix one of the variables placed into the 3 + 1 HUP. This is a deterministic input into a derivation which is then First of all, we restate a proof of a highly localized special case of a metric tensor uncertainty principle first written up by Unruh. Unruh did not use the Roberson-Walker geometry which we do, and it so happens that the dominant metric tensor we will be examining, is variation in δg<sub>tt</sub>. The metric tensor variations are given by δg<sub>rr</sub>, δg<sub>θθ</sub> and δg<sub>φφ</sub> are negligible, as compared to the variation δg<sub>tt</sub>. From there the expression for the HUP and its applications into certain cases in the early universe are strictly affected after we take into consideration a vanishingly small r spatial value in how we define δg<sub>tt</sub>. 展开更多
关键词 Massive Gravitons Heisenberg Uncertainty Principle (hup) Riemannian-Penrose Inequality
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Gedanken Experiment for Looking at δgtt for Initial Expansion of the Universe and Influence on HUP via Dynamical Systems, with Positive Pre-Planckian Acceleration 被引量:1
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作者 Andrew Walcott Beckwith 《Journal of High Energy Physics, Gravitation and Cosmology》 2016年第4期531-545,共15页
We examine through the lens of dynamical systems a “one dimensional” time mapping of emergent VEV from Pre-Planckian space time conditions. As it is, we will from first principles examine what adding acceleration do... We examine through the lens of dynamical systems a “one dimensional” time mapping of emergent VEV from Pre-Planckian space time conditions. As it is, we will from first principles examine what adding acceleration does as to the HUP previously derived. In doing so, we will be trying it in our discussion with the earlier work done on the HUP. not equal to zero, constant, but large would frequently imply which would have three dissimilar real valued roots. And the situation with not equal to zero yields more tractable result for which will have implications for the HUP inequality in Pre-Planckian space-time, and buttresses an analysis of a 1 dimensional “time” mapping for emergent VEV (vacuum expectation values). 展开更多
关键词 hup Dynamical Systems
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基于PCA-HUP模型的洪水预报不确定性分析——以信江流域梅港站为例
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作者 冻芳芳 刘沁薇 +1 位作者 王淑梅 刘建伟 《人民长江》 北大核心 2021年第4期22-26,共5页
针对梅港站洪水预报过程中存在的不确定性,采用主成分分析技术(PCA)与水文不确定性处理器(HUP)耦合的PCA-HUP模型,对梅港站洪水预报不确定性进行了分析,并提供了中位数(Q50)定值预报和90%置信度下的预报区间成果。结果表明:就确定性系... 针对梅港站洪水预报过程中存在的不确定性,采用主成分分析技术(PCA)与水文不确定性处理器(HUP)耦合的PCA-HUP模型,对梅港站洪水预报不确定性进行了分析,并提供了中位数(Q50)定值预报和90%置信度下的预报区间成果。结果表明:就确定性系数和洪峰相对误差指标而言,PCA-HUP模型的Q50定值预报成果优于原模型的定值预报成果;就离散度和覆盖率指标而言,PCA-HUP模型90%置信度下的预报区间具有较小的离散度且保证了较高的覆盖率。总体而言,PCA-HUP模型具有较高的精度及可靠性。 展开更多
关键词 洪水预报 不确定性分析 PCA-hup模型 梅港站 信江流域
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How 5 Dimensions May Fix a Deterministic Background Spatially as to Be Inserted for HUP in 3 + 1 Dimensions, and Its Relevance to the Early Universe? Criteria for Massive Graviton Detection from Relic Conditions Mentioned
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作者 Andrew Walcott Beckwith 《Journal of High Energy Physics, Gravitation and Cosmology》 CAS 2023年第1期108-115,共8页
We will first of all reference a value of momentum, in the early universe. This is for 3 + 1 dimensions and is important since Wesson has an integration of this momentum with regards to a 5 dimensional parameter inclu... We will first of all reference a value of momentum, in the early universe. This is for 3 + 1 dimensions and is important since Wesson has an integration of this momentum with regards to a 5 dimensional parameter included in an integration of momentum over space which equals a ration of L divided by small l (length) and all these times a constant. The ratio of L over small l is a way of making deterministic inputs from 5 dimensions into the 3 + 1 dimensional HUP. In doing so, we come up with a very small radial component for reasons which due to an argument from Wesson is a way to deterministically fix one of the variables placed into the 3 + 1 HUP. This is a deterministic input into a derivation which is then, first of all, we restate a proof of a highly localized special case of a metric tensor uncertainty principle first written up by Unruh. Unruh did not use the Roberson-Walker geometry which we do, and it so happens that the dominant metric tensor we will be examining is variation in δg<sub>tt</sub>. We state that the metric tensor variations are given by δg<sub>rr</sub>, δg<sub>θθ</sub> and δg<sub>φφ</sub> are negligible contributions, as compared to the variation δg<sub>tt</sub>. From there the expression for the HUP and its applications into certain cases in the early universe are strictly affected after we take into consideration a vanishingly small r spatial value in how we define δg<sub>tt</sub>. 展开更多
关键词 Massive Gravitons Heisenberg Uncertainty Principle (hup) Riemannian-Penrose Inequality
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含hup基因的质粒在催娩克氏杆菌中的稳定性及吸氢酶的表达
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作者 黄黎 梁建光 吴永强 《植物生理学报(0257-4829)》 CSCD 2001年第1期15-20,共6页
以质粒 pKT2 30为载体 ,亚克隆大豆根瘤菌吸氢酶结构基因 (hupSL )片段 ,构建成嵌合质粒pKH1。将质粒分配系统基因 ( parDE)片段和吸氢酶结构基因 (hup )片段插入载体质粒pRK415 ,构建成质粒 pRKBH。质粒 pKH1、pRKBH和载体 pRK415经转... 以质粒 pKT2 30为载体 ,亚克隆大豆根瘤菌吸氢酶结构基因 (hupSL )片段 ,构建成嵌合质粒pKH1。将质粒分配系统基因 ( parDE)片段和吸氢酶结构基因 (hup )片段插入载体质粒pRK415 ,构建成质粒 pRKBH。质粒 pKH1、pRKBH和载体 pRK415经转化和三亲本杂交 ,得到DH5α/pHR11、DH5α/pRKBH、E12 0 1/pKH1、NG13/pKH1(NGH999)、NG1390 /pRK415、NG1390 /pHR11、NG1390 /pRKBH和NG1390 /pKH1(NGH982 )等接合子。稳定性分析发现 ,质粒 pKH1在催娩克氏杆菌中传 80代后仍有92 %以上的菌株含此质粒 ,说明质粒 pKH1有较高的稳定性。吸氢酶活性分析表明 ,H2 诱导接合子NGH999和NGH982吸氢酶活性高表达 ,同时固氮效率和固氮酶活性也高。低碳源浓度更有利于接合子吸氢酶活性的表达和固氮效率的提高。接合子NGH982具有耐铵的基因 。 展开更多
关键词 催娩克氏杆菌 质粒稳定性 吸氢酶活性 吸氢酶基因 水稻 固氮菌
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几种水稻联合固氮菌吸氢酶(hup)基因的鉴定及分析
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作者 苑红丽 王惠贤 尤崇杓 《核农学报》 CAS CSCD 1990年第1期19-24,共6页
供试菌株Alcaligenes faecalis A15,Enterobacter cloacae EnSs.E·cl-oacae E26,Klebsiella planticola DWUL2.K·oxytoca NG13和Pseudomonassacharophila均能还原2,3,5-氯化三苯基四氮唑(TTC),说明它们含有吸氢酶。以Rhizobiu... 供试菌株Alcaligenes faecalis A15,Enterobacter cloacae EnSs.E·cl-oacae E26,Klebsiella planticola DWUL2.K·oxytoca NG13和Pseudomonassacharophila均能还原2,3,5-氯化三苯基四氮唑(TTC),说明它们含有吸氢酶。以Rhizobium japonicum的hup基因为探针进行杂交的结果表明。除E·oloacae E26和K·oxytoca NG13外,其它菌株的DNA与hup探针具有同源性。A·faecalis A15 hup基因位于染色体上‘E·cloacae EnSs则位于较大的一个质粒上。A·faecalis A15和E·Cloacae EnSs的nif基因与hup基因位于同一复制子上。hup基因不具必然的保守性,因此异源hup基因探针不一定都适宜于探测hup基因。 展开更多
关键词 水稻 联合固氮菌 吸氢酶 基因 固氮
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交通地下空间体系建设发展对策研究 被引量:3
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作者 肖旦强 詹伟 +3 位作者 胡智 严鑫 余以强 吴剑军 《岩土工程学报》 EI CAS CSCD 北大核心 2024年第S02期130-134,共5页
工业化、城市化的快速推进导致城市用地紧缺、交通拥堵等问题日益突出,交通地下空间开发通过统筹考虑地下、地面和地上的开发和利用,打造综合枢纽,形成立体交通,已经成为提升交通系统整体运行效率的重要解决方案。各地的城市交通地下空... 工业化、城市化的快速推进导致城市用地紧缺、交通拥堵等问题日益突出,交通地下空间开发通过统筹考虑地下、地面和地上的开发和利用,打造综合枢纽,形成立体交通,已经成为提升交通系统整体运行效率的重要解决方案。各地的城市交通地下空间正进入快速建设时期,其深度和广度显著提升,引起了一系列全新的难题和挑战。结合国内交通地下空间开发及政策现状,从时间、空间和类型等多个层面总结先进经验,并从中梳理制约交通地下空间发展的问题与难点,针对提出的重难点问题,提出交通地下空间发展总体思路与对策,对未来交通地下空间的建设开发给予建议和参考。 展开更多
关键词 交通地下空间 地下枢纽 开发政策 发展对策
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基于水文—水力学耦合的淮河中游河道洪水预报及不确定性分析 被引量:10
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作者 李大洋 梁忠民 +1 位作者 周艳 黄一昕 《水电能源科学》 北大核心 2017年第12期44-47,13,共5页
淮河王家坝至鲁台子的中游干流,河道平缓,复式断面特征明显,单纯以传统的水文模型进行洪水预报难度较大。为此,利用新安江模型进行上游及区间入流预报,采用MIKE11水动力学模型进行主要支流及干流洪水演算,从而建立了淮河中游河道洪水预... 淮河王家坝至鲁台子的中游干流,河道平缓,复式断面特征明显,单纯以传统的水文模型进行洪水预报难度较大。为此,利用新安江模型进行上游及区间入流预报,采用MIKE11水动力学模型进行主要支流及干流洪水演算,从而建立了淮河中游河道洪水预报方案。选取1990~2012年间的场次洪水资料,采用SCE-UA优化算法分别对新安江模型参数和MIKE11的糙率系数进行率定与验证,并使用水文不确定性处理器(HUP)对预报结果进行不确定性分析。结果表明,模型预报结果具有较高精度,不确定程度较小,并可提供某一置信度的预报区间,为实时作业提供参考。 展开更多
关键词 河道洪水预报 新安江模型 MIKE11模型 水文—水力学耦合 SCE-UA hup
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补中益气汤对阿霉素诱导的大鼠肾病的作用 被引量:3
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作者 郭继光 张海燕 +2 位作者 李朝鹏 高飒 李芸 《河北大学学报(自然科学版)》 CAS 北大核心 2015年第3期298-304,共7页
以阿霉素肾病大鼠模型为研究对象,采用了血液生化学和组织病理学方法,分析了补中益气汤对阿霉素肾病的作用和可能的机制.Wistar雄性大鼠60只,随机分为对照组(n=10)、模型组(n=10)、激素组(n=10)和补中益气汤低剂量组(n=10)、中剂量组(n=... 以阿霉素肾病大鼠模型为研究对象,采用了血液生化学和组织病理学方法,分析了补中益气汤对阿霉素肾病的作用和可能的机制.Wistar雄性大鼠60只,随机分为对照组(n=10)、模型组(n=10)、激素组(n=10)和补中益气汤低剂量组(n=10)、中剂量组(n=10)和高剂量组(n=10).采用阿霉素二次尾静脉注射法(首次6mg/kg,二次3mg/kg)制作阿霉素肾病的大鼠模型.在阿霉素注射后7,21,42d将大鼠置于代谢笼中分别收集24h尿液,测定24h尿蛋白.末次给药后,眼眶取血检测肾功能指标,包括肌肝SCR(serum creatine)和尿素氮BUN(blood urea nitrogen);处死大鼠并观察肾组织病理改变.结果表明:补中益气汤可以显著减少尿蛋白的排泄并缓解肾皮质上皮细胞的病理学改变.这提示补中益气汤对阿霉素大鼠能够通过改善尿蛋白的排泄,缓解肾脏病理改变,从而起到对肾脏的保护作用. 展开更多
关键词 阿霉素肾病 补中益气汤 24 h尿蛋白 肌酐 尿素氮 24-hour URINE protein (24 hup)
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含花生根瘤菌吸氢基因重组质粒pZ-55的特性分析 被引量:2
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作者 王建锋 张凤章 +2 位作者 龙敏南 王刚 许良树 《植物生理学报(0257-4829)》 CSCD 2000年第1期23-26,共4页
应用含豌豆根瘤菌部分吸氢基因的探针及PCR分析,从花生根瘤菌基因文库中筛选到含有吸氢基因的重组质粒pZ55。用BamHⅠ、EcoRⅠ和KpnⅠ等内切酶对pZ55进行酶切分析,构建了pZ55的酶切物理图谱。经三亲本杂交... 应用含豌豆根瘤菌部分吸氢基因的探针及PCR分析,从花生根瘤菌基因文库中筛选到含有吸氢基因的重组质粒pZ55。用BamHⅠ、EcoRⅠ和KpnⅠ等内切酶对pZ55进行酶切分析,构建了pZ55的酶切物理图谱。经三亲本杂交分析,pZ55能互补诱变株Ln1(Hup-),获得在自生条件下表达吸氢活性。 展开更多
关键词 花生根瘤菌 hup基因 重组质粒pZ-55 吸氢活性
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淮河梅山水库流域洪水模拟不确定性分析 被引量:3
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作者 李彬权 梁忠民 +3 位作者 杨晓甜 吕圣岚 孙浩 陈腾 《治淮》 2018年第4期24-26,共3页
由于自然水文过程的复杂性和人类认识水平的局限性,应用水文模型进行模拟和预报时不可避免地存在着诸如降水输入、模型结构和参数的不确定性,由此导致洪水模拟和预报结果的不确定性。基于三水源新安江水文模型,分析贝叶斯预报系统(BFS)... 由于自然水文过程的复杂性和人类认识水平的局限性,应用水文模型进行模拟和预报时不可避免地存在着诸如降水输入、模型结构和参数的不确定性,由此导致洪水模拟和预报结果的不确定性。基于三水源新安江水文模型,分析贝叶斯预报系统(BFS)-水文不确定性处理器(HUP)在淮河梅山水库入库洪水模拟不确定性分析中适用性。通过对入库洪水模拟结果的不确定性量化,实现梅山水库入库洪水概率预报。结果表明,与确定性洪水预报相比,基于不确定性分析的洪水概率预报在提供均值预报的同时还能给出更为丰富的不确定性信息(如90%预报置信区间)。 展开更多
关键词 洪水模拟 水文不确定性处理器hup 不确定性分析 梅山水库流域
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Hanta病毒肺综合征(一种新病毒引起的疾病的暴发流行)
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作者 范永琛 张嘉红 《武汉医学杂志》 1996年第3期182-183,共2页
1993年5月在美国新墨西哥城发现一起21岁女子与一名同居19岁男子因不明原因而死亡。据察两人死前5天患有同样疾病,即突发咳嗽、发热、肌痛,头痛,迅即出现非心源性肺水肿。患者死后8天,女方兄弟也出现相似症状,4天后兄弟的妻子又患同样... 1993年5月在美国新墨西哥城发现一起21岁女子与一名同居19岁男子因不明原因而死亡。据察两人死前5天患有同样疾病,即突发咳嗽、发热、肌痛,头痛,迅即出现非心源性肺水肿。患者死后8天,女方兄弟也出现相似症状,4天后兄弟的妻子又患同样疾病。同年6月共发现24名患者患这一奇特疾病,其中12例死亡。回顾病史发现有的患者1992年底已起病。这些病例都居住在美国尤他州、可罗拉多州、新墨西哥州和亚利桑那州四州交界处,多数患者过去是健康青年。 展开更多
关键词 Hanta病毒 肺综合征 hupS 病例报告
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