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HS-GC-MS法测定盐酸苯达莫司汀(一水合物)中环氧乙烷含量残留
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作者 杜超 卓秋琪 刘艳平 《化工与医药工程》 2026年第1期30-37,共8页
建立基于顶空气相色谱质谱联用法(HS-GC-MS)对盐酸苯达莫司汀(一水合物)中环氧乙烷含量快速检测的方法。采用超高惰性色谱柱(DB-624UI,30 m×0.25 mm×1.4 um),载气为高纯氦气,流速:1 mL/min,分流比为50∶1,进样口温度:100℃,... 建立基于顶空气相色谱质谱联用法(HS-GC-MS)对盐酸苯达莫司汀(一水合物)中环氧乙烷含量快速检测的方法。采用超高惰性色谱柱(DB-624UI,30 m×0.25 mm×1.4 um),载气为高纯氦气,流速:1 mL/min,分流比为50∶1,进样口温度:100℃,程序升温法。离子源类型为EI,扫描模式为SIM,质量扫描范围:44 m/z。环氧乙烷在44.87~359.0 ng/mL浓度范围内线性关系良好(r=0.998);平均回收率为99.98%(RSD=8.79%,n=9);重复性试验RSD为2.49%(n=6),中间精密度RSD为2.04%(n=6),样品溶液在21 h内稳定性良好。该方法简便、快速、准确、灵敏度高,适用于盐酸苯达莫司汀(一水合物)中环氧乙烷残留量的测定。 展开更多
关键词 盐酸苯达莫司汀(一水合物) 环氧乙烷 hs-gc-ms
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Advances in interdisciplinary ocean geoscience and technology
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作者 Jian LIN Wule LIN +1 位作者 Zhiyuan ZHOU Fan ZHANG 《Science China Earth Sciences》 2026年第2期463-477,共15页
Ocean geoscience is a highly integrated and interdisciplinary field that plays a critical role in understanding the interaction between Earth’s lithosphere,hydrosphere,atmosphere,biosphere,and anthroposphere.Recent y... Ocean geoscience is a highly integrated and interdisciplinary field that plays a critical role in understanding the interaction between Earth’s lithosphere,hydrosphere,atmosphere,biosphere,and anthroposphere.Recent years have seen tremendous progress in global ocean research,driven by rapid advancements in deep-sea manned and unmanned submersibles,ocean drilling,seafloor observatories,big data assimilation,and supercomputing simulations.Representative examples of breakthroughs are highlighted in this work:(1)Probing sub-seafloor processes.A 10,000-meter ocean-bottom seismometer array has achieved high-resolution imaging of the deepest ocean on the Earth-the Challenger Deep of the Mariana Trench,revealing the role of key tectonic and hydrological processes within the subduction zone.The first sub-ice seafloor seismic and magnetotelluric experiments were successfully conducted at the Arctic Gakkel Ridge,providing significant insights into the dynamics of ultraslow seafloor spreading.(2)Exploration of seafloor resources.Near-seafloor investigations employing underwater robotics and multi-sensor systems have been carried out in areas of hydrothermal vents and cold seeps at global locations,including the Southwest Indian Ridge.These efforts have combined geophysical,oceanographic,chemical,and biological observations with extensive seafloor sampling.(3)Interdisciplinary research of complex catastrophic events.High-resolution simulations integrating ocean observations with supercomputing modeling have made it possible to fully model earthquake-induced seafloor deformation,tsunami propagation,and ocean basin-scale transport of the Fukushima Power Plant-derived radionuclides associated with the 2011 Tohoku earthquake.Among the world’s three major oceans,the Indian Ocean is still relatively underexplored.Major scientific challenges include elucidating crust-mantle interaction,air-sea dynamic coupling,large-scale marine hazards,and responses of ecosystems to major environmental changes,all of which require interdisciplinary collaboration.Future efforts should focus on developing intelligent unmanned observation platform systems,big data and digital twins,and AI-driven hazard modeling.Meanwhile,higher educational reforms should emphasize fostering a new generation of students and young scientists with a solid background and strong critical analysis skills to accelerate technological innovation. 展开更多
关键词 Ocean geoscience Cutting-edge ocean technology Deep-sea science and technology Multi-sphere coupling Sustainable development
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Research on the Optimal Allocation of Community Elderly Care Service Resources Based on Big Data Technology
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作者 Shuying Li 《Journal of Clinical and Nursing Research》 2026年第1期241-246,共6页
With the accelerating aging process of China’s population,the demand for community elderly care services has shown diversified and personalized characteristics.However,problems such as insufficient total care service... With the accelerating aging process of China’s population,the demand for community elderly care services has shown diversified and personalized characteristics.However,problems such as insufficient total care service resources,uneven distribution,and prominent supply-demand contradictions have seriously affected service quality.Big data technology,with core advantages including data collection,analysis and mining,and accurate prediction,provides a new solution for the allocation of community elderly care service resources.This paper systematically studies the application value of big data technology in the allocation of community elderly care service resources from three aspects:resource allocation efficiency,service accuracy,and management intelligence.Combined with practical needs,it proposes optimal allocation strategies such as building a big data analysis platform and accurately grasping the elderly’s care needs,striving to provide operable path references for the construction of community elderly care service systems,promoting the early realization of the elderly care service goal of“adequate support and proper care for the elderly”,and boosting the high-quality development of China’s elderly care service industry. 展开更多
关键词 Big data technology COMMUNITY Elderly care Service resources
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Tracking a High-Tech Transition--How technology is powering Guangdong’s manufacturing transformation
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作者 HU FAN 《ChinAfrica》 2026年第1期30-32,共3页
The moment a media delegation from the Republic of the Congo arrived at the Othello Kitchenware Museum on 18 November 2025,they were greeted with a vivid show of Guangdong’s industrial strength.Standing before them w... The moment a media delegation from the Republic of the Congo arrived at the Othello Kitchenware Museum on 18 November 2025,they were greeted with a vivid show of Guangdong’s industrial strength.Standing before them was not a typical exhibition hall,but a building shaped like a gleaming stainless-steel cooking pot. 展开更多
关键词 othello kitchenware museum technology industrial strength high tech transition guangdong manufacturing transformation
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Setting the standard! The technology that shapes 40% of the world's denim finishing
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《China Textile》 2026年第1期44-44,共1页
Jeanologia celebrated its 30th anniversary reaffirming the mission it was born with in 1994,to transform the textile industry into a more sustainable,efficient,and human-centered sector.Three decades later,that vision... Jeanologia celebrated its 30th anniversary reaffirming the mission it was born with in 1994,to transform the textile industry into a more sustainable,efficient,and human-centered sector.Three decades later,that vision has become a global reality.Today,more than 40 percent of all jeans produced worldwide are made using technologies developed by the Valencia-based company.What started in a small laboratory in Valencia(Spain),with a pioneering team and a visionary idea,has evolved into a global benchmark in sustainable innovation.From the beginning,Jeanologia believed in technology as a driver of change,introducing solutions that eliminated harmful practices and opened the door to a new,cleaner way of making garments. 展开更多
关键词 technological transformation environmental impact textile industry garment production DENIM jeanologia sustainability innovation
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Reform of Teacher-Machine-Student Interactive Teaching Model of“HarmonyOS Development Technology”Course Based on Congyou Platform
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作者 Yixian Liu Jun Guo +1 位作者 Dongming Chen Zhiliang Zhu 《计算机教育》 2026年第3期158-166,共9页
Aiming at the problems of lagging curriculum,weak practice,and single evaluation in the cultivation of HarmonyOS Development talents,this study constructs a“teacher-machine-student”ternary interactive teaching model... Aiming at the problems of lagging curriculum,weak practice,and single evaluation in the cultivation of HarmonyOS Development talents,this study constructs a“teacher-machine-student”ternary interactive teaching model based on the Congyou platform.Through the building block curriculum system,the HarmonyOS technology stack is decoupled into dynamic capability units,and a multi-disciplinary cross-case library is jointly built with Huawei,which significantly improves the synchronization of teaching content and industrial technology.This paper innovatively designs an AI collaborative teaching system,which employs knowledge graphs to plan learning paths,utilizes virtual equipment clusters to simulate development environments,and establishes a“diagnosis-feedback-enhancement”closed loop through AI-based review,thereby effectively improving students’development efficiency and code reuse rate.A three-dimensional evaluation model integrating task outcomes,process performance,and innovation is constructed,incorporating indicators such as code standardization and an innovation index to strengthen the cultivation of engineering thinking and innovative ability.Furthermore,a data-driven support platform is built to generate student competency profiles,open up the“credit-competency-certification”pathway,promote the transformation of course achievements into contributions to the Huawei ecosystem,and significantly shorten the job adaptation cycle for graduates.The research results provide a replicable paradigm for the cultivation of domestic operating system talents. 展开更多
关键词 Interactive teaching model HarmonyOS development technology Building-block curriculum system Domestic software ecosystem
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Chinese Rural Women's Social Media Use: An Empirical Study Adopting the Technology Acceptance Model
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作者 Zhang Hui Mahadevan Krishnan 《Contemporary Social Sciences》 2026年第1期104-122,共19页
Given the growing importance of social media in digital rural development, this study systematically investigated the influence pathways of social media use among rural women in China, drawing on the Technology Accept... Given the growing importance of social media in digital rural development, this study systematically investigated the influence pathways of social media use among rural women in China, drawing on the Technology Acceptance Model(TAM). Employing quantitative research methods, the study conducted empirical tests based on 367 valid questionnaires using Partial Least Squares Structural Equation Modeling(PLS-SEM) via SmartPLS 4.0 software. Results indicate that significant associations exist between perceived ease of use, perceived usefulness, attitudes toward use, behavioral intention, and actual usage behavior. Specifically, the study finds that rural women's perceived ease of use of social media has a significant and positive influence on both perceived usefulness and attitudes toward use. Perceived usefulness further significantly promotes attitudes toward use and behavioral intention. Moreover, positive attitudes toward usage and strong behavioral intentions were effectively converted into actual social media usage behaviors. This study not only validates the applicability and explanatory power of the TAM model in understanding the digital behavior of Chinese rural women but also provides quantitative evidence for how social media enhances their “digital visibility.” These findings offer practical insights for governments and platform providers to optimize user experiences and strengthen digital skills training. Despite its limitations, including a cross-sectional design and a regional sample, this research holds significant theoretical and practical implications. 展开更多
关键词 Chinese rural women social media technology Acceptance Model(TAM) digital visibility
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Between Themis and Prometheus:a history of the ethics of science and technology
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作者 Jia-Yun Chen Zong-Zhen Wu +7 位作者 Qiang-Yu Xiang Lu Zhang Jia-Lin Diao Ya-Hui Zhang Shen-Shen Yan Kun-Lan Zuo Jian-Liang Huang Huan Liu 《History and Philosophy of Medicine》 2026年第1期49-59,共11页
Background:With the rapid development of modern emerging technologies,the ethical dilemmas and social controversies triggered by scientific and technological activities have become increasingly prominent.How to guide ... Background:With the rapid development of modern emerging technologies,the ethical dilemmas and social controversies triggered by scientific and technological activities have become increasingly prominent.How to guide technology for good and prevent and control technological risks has become an important issue of global concern.Research on science and technology ethics is dedicated to integrating ethical theories into governance practices and constructing ethical models that adapt to the development of the times.Methods:This article systematically reviews the six core approaches of scientific and technological ethics thought,including technological autonomy and political philosophy criticism,responsibility ethics and intergenerational obligations,technological intermediation and the integration of life and the world,ethical principles and normative frameworks,participatory governance and ethical practice innovation,as well as domain-specific ethical norms,thereby constructing an ethical analysis framework applicable to medical technology risks.And cross-analysis was conducted by taking medical events such as gene editing and xenotransplantation as examples.Results:Research shows that a single ethical approach has limitations in addressing complex medical ethical challenges,while the six approaches are complementary and synergistic.By criticizing technological autonomy,establishing a responsibility ethics orientation,setting the bottom line of ethical principles,promoting participatory governance,formulating domain norms,and continuously reflecting on the intermediary nature of technology,a multi-level and dynamically adaptive governance system for scientific and technological ethics can be constructed.Conclusion:The key to addressing contemporary medical ethics challenges lies in the comprehensive application of science and technology ethics theories and the integration of ethical considerations throughout the entire process of scientific and technological research and development.In the future,a governance framework that adapts to the development of new technologies should be established to promote cross-cultural and cross-disciplinary ethical dialogue and public participation,ensuring that scientific and technological innovation always serves the dignity of human life and overall well-being. 展开更多
关键词 ethics of science and technology history of science ethical governance responsible innovation medical ethics
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Teaching Reform of Chinese Medicine Processing Technology Course under the Integration of Technical and Higher Vocational Education
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作者 Lianfang LI 《Medicinal Plant》 2026年第1期72-77,82,共7页
Against the backdrop of integrated development between technical education and higher vocational education,the teaching of Chinese Medicine Processing Technology courses faces new opportunities and challenges.This pap... Against the backdrop of integrated development between technical education and higher vocational education,the teaching of Chinese Medicine Processing Technology courses faces new opportunities and challenges.This paper analyzes the existing problems in the current teaching of Chinese Medicine Processing Technology courses,discusses the necessity of reforming the teaching model under the context of integration,and proposes the construction of a"Dual-Capability Progression,Six-Dimensional Empowerment"teaching model.The aim is to enhance the teaching quality of Chinese Medicine Processing Technology courses and cultivate high-quality skilled talents in Chinese medicine processing who can meet industry demands. 展开更多
关键词 Technical education Higher vocational education Integrated development Chinese Medicine Processing technology Course Teaching reform
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Optical lateral flow immune assay technology for body fluid sensing
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作者 Chen Liu Tianqi Zhao +5 位作者 Jialing Zhou Xiaoyun Hu Dinghao Pan Jinlong Li Wei Li Zhihui Dai 《Chinese Chemical Letters》 2026年第1期106-115,共10页
Detecting biomarkers in body fluids by optical lateral flow immune assay(LFIA) technology provides rapid access to disease information for early diagnosis.LFIA is based on an antigen-antibody reaction and is rapidly b... Detecting biomarkers in body fluids by optical lateral flow immune assay(LFIA) technology provides rapid access to disease information for early diagnosis.LFIA is based on an antigen-antibody reaction and is rapidly becoming the preferred choice of physicians and patients for point-of-care testing due to its simplicity,cost-effectiveness,and rapid detection.Observing the optical signal change from the colloidal gold of the traditional LFIA strip has been widely applied for various biomarkers detection in body fluids.Despite the significant progress,rapid real-time detection of color changes in the colloidal gold by the naked eye still faces many limitations,such as large errors and the inability to quantify and accurately detect.New optical LFIA strip technology has emerged in recent years to extend its application scenarios for achieving quantitative detection such as fluorescence,afterglow,and chemiluminescence.Herein,we summarized the development of optical LFIA technology from single to hyphenated optical signals for biomarkers detection in body fluids from invasive and non-invasive sources.Moreover,the challenge and outlook of optical LFIA strip technology are highlighted to inspire the designing of next-generation diagnostic platforms. 展开更多
关键词 Optical signal Lateral flow immune assay Hyphenated optical technology Body fluid sensing Point-of-care testing
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Application of Whole Slide Imaging Technology in Clinical Pathological Diagnosis
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作者 Zhenjie Wang Jianguo Huai 《Journal of Clinical and Nursing Research》 2026年第1期21-26,共6页
Whole Slide Imaging (WSI) technology, as a revolutionary digital technology in the field of pathology, is gradually changing the traditional clinical pathological diagnosis model. By converting traditional glass patho... Whole Slide Imaging (WSI) technology, as a revolutionary digital technology in the field of pathology, is gradually changing the traditional clinical pathological diagnosis model. By converting traditional glass pathological sections into complete digital images through high-resolution scanning, it provides a new method for pathological diagnosis. Based on this, this paper studies the application of WSI technology in clinical pathological diagnosis, elaborates on its application value, analyzes the current application status, and proposes corresponding application countermeasures, aiming to provide reference for the standardized and popularized development of this technology in clinical pathological diagnosis. 展开更多
关键词 Whole slide imaging(WSI)technology Clinical pathological diagnosis Application value Current status Application countermeasures
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Defence Technology Aims and Scope
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《Defence Technology(防务技术)》 2026年第2期F0002-F0002,共1页
Defence Technology(ISSN 2214-9147(O);2096-3459(P)),sponsored by China Ordnance Society,is published monthly and aims to become one of the well-known comprehensive journals in the world,which reports on the breakthroug... Defence Technology(ISSN 2214-9147(O);2096-3459(P)),sponsored by China Ordnance Society,is published monthly and aims to become one of the well-known comprehensive journals in the world,which reports on the breakthroughs in defence technology by building up an international academic exchange platform for the defence technology related research.It publishes original research papers having direct bearing on defence,with a balanced coverage on analytical,experimental,numerical simulation and applied investigations.It covers various disciplines of science,technology and engineering. 展开更多
关键词 defence technology applied investigation original research papers analytical methods academic exchange platform breakthroughs experimental methods international academic exchange
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Low-temperature bonding of W90 tungsten heavy alloy using Sn−2Al filler metal by ultrasonic-assisted coating technology
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作者 Xiao-guo SONG Xu-dong ZHANG +3 位作者 Wei FU Xiao-yu TIAN Guang-dong WU Sheng-peng HU 《Transactions of Nonferrous Metals Society of China》 2026年第1期259-272,共14页
The Sn−2Al filler metal was utilized to bond W90 tungsten heavy alloys by the ultrasonic-assisted coating technology in atmospheric environment at 250℃.The effects of ultrasonic power and ultrasonic time on microstru... The Sn−2Al filler metal was utilized to bond W90 tungsten heavy alloys by the ultrasonic-assisted coating technology in atmospheric environment at 250℃.The effects of ultrasonic power and ultrasonic time on microstructure and interfacial strength of Sn−2Al/W90 interface were investigated.The ultrasound improved the wettability of Sn−2Al filler metal on W90 surface.As the ultrasonic power increased and ultrasonic time increased,the size of Al phase in seam decreased.The maximum value of Sn−2Al/W90 interfacial strength reached 30.1 MPa.Based on the acoustic pressure simulation and bubble dynamics,the intensity of cavitation effect was proportional to ultrasonic power.The generated high temperature and high pressure by cavitation effect reached 83799.6 K and 1.26×10^(14) Pa,respectively. 展开更多
关键词 W−Ni−Fe alloy Sn−Al filler metal ultrasonic-assisted coating technology acoustic pressure CAVITATION bubble dynamics
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A review of microfluidic technology for CO_(2)sequestration in saline aquifers
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作者 Yiyan Zhong Qi Li +2 位作者 Wenbin Gao Yiping Wen Yao Zhang 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第1期810-829,共20页
In recent years,microfluidic technology has emerged as a powerful and innovative tool,attracting significant attention for its ability to provide real-time visualization of CO_(2)flow,mass transfer,and reaction proces... In recent years,microfluidic technology has emerged as a powerful and innovative tool,attracting significant attention for its ability to provide real-time visualization of CO_(2)flow,mass transfer,and reaction processes in porous media.This review examines the application of microfluidic technology in CO_(2)sequestration in saline aquifers,emphasizing the advantages of saline aquifer for geological sequestration,including safety,high storage capacity,stability,and cost-effectiveness.The materials used for microfluidic chips and the design of microchannels are systematically reviewed,offering forward-looking recommendations for chip selection and microchannel characterization in future research on CO_(2)sequestration in saline aquifer.Based on a detailed analysis of advancements in microfluidic technology,this review highlights key findings related to CO_(2)trapping mechanisms,salt precipitation,and CO_(2)-water-rock chemical interactions within saline aquifers.Although microfluidic technology shows great promise in these areas,this review identifies limitations in current studies and outlines future research directions,aiming to promote further innovation and broader application of microfluidic technology in the field of CO_(2)sequestration in saline aquifer. 展开更多
关键词 Microfluidic technology Chip materials Microchannel fabrication CO_(2)trapping mechanisms Salt precipitation CO_(2)-water-rock interaction
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HS-GC-MS分析不同粉碎工艺僵蚕及其炮制品的挥发性成分
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作者 王媚 乔安平 +5 位作者 薛蕙 崔春利 张小飞 邹俊波 郭东艳 史亚军 《陕西中医药大学学报》 2025年第6期86-93,共8页
目的比较传统中药僵蚕三种炮制品(生僵蚕、姜炙僵蚕、清炒僵蚕)不同粒径(研磨、细粉、超微粉)的挥发性成分,为进一步研究僵蚕的药用价值提供依据。方法采用顶空进样提取僵蚕的挥发性成分,通过气相色谱-质谱联用仪对其进行鉴定,并利用峰... 目的比较传统中药僵蚕三种炮制品(生僵蚕、姜炙僵蚕、清炒僵蚕)不同粒径(研磨、细粉、超微粉)的挥发性成分,为进一步研究僵蚕的药用价值提供依据。方法采用顶空进样提取僵蚕的挥发性成分,通过气相色谱-质谱联用仪对其进行鉴定,并利用峰面积归一化法计算各组分相对百分含量。结果研磨粉中生僵蚕、姜炙僵蚕、清炒僵蚕分别被检测出57、54、37种挥发性成分,主要成分分别为烷烃类(44.12%)、烷烃类(24.83%)、烯烃类(72.62%);细粉中生僵蚕、姜炙僵蚕、清炒僵蚕分别被检测出109、114、92种挥发性成分,主要成分分别为羧酸类(36.83%)、羧酸类(34.77%)、烯烃类(57.84%);超微粉生僵蚕、姜炙僵蚕、清炒僵蚕分别被检测出143、101、100种挥发性成分,主要成分分别为醇类(68.65%)、羧酸类(32.33%)、烯烃类(56.73%)。结论僵蚕经炮制后,姜炙品和清炒品中的苯甲醛、正己醛、金合欢醇、A-毕橙茄醇等刺激成分含量降低,α-蒎烯、乙酸、2,6-二甲基吡嗪、2,3-二甲基吡嗪等含量增加;粉碎得越细,被检测出的挥发性成分越多。这将为僵蚕炮制原理的研究提供参考。 展开更多
关键词 生僵蚕 姜炙僵蚕 清炒僵蚕 粉碎工艺 顶空气相色谱-质谱法(hs-gc-ms) 挥发性成分 定性分析
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基于HS-GC-MS及智能感官技术分析赤石脂炒陈皮炮制前后的挥发性成分差异 被引量:5
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作者 辛力 温佳文 +6 位作者 龚文慧 赵蓓蓓 严世豪 陈华师 乐海平 张金莲 薛艳华 《中国实验方剂学杂志》 北大核心 2025年第7期157-162,共6页
目的:通过分析赤石脂炒陈皮炮制前后颜色、气味及挥发性成分的差异,探讨炮制后健脾功效增强的物质基础及辅料赤石脂炮制饮片的科学内涵。方法:通过顶空气相色谱-质谱法(HS-GC-MS)对炮制前后样品的挥发性成分进行鉴定及相对定量,利用主... 目的:通过分析赤石脂炒陈皮炮制前后颜色、气味及挥发性成分的差异,探讨炮制后健脾功效增强的物质基础及辅料赤石脂炮制饮片的科学内涵。方法:通过顶空气相色谱-质谱法(HS-GC-MS)对炮制前后样品的挥发性成分进行鉴定及相对定量,利用主成分分析(PCA)和正交偏最小二乘法-判别分析(OPLS-DA)对其挥发性成分进行分析,根据变量重要性投影(VIP)值>1.5的原则筛选得到炮制前后的挥发性差异成分,并结合色差仪、电子鼻等智能感官技术识别经赤石脂炒制前后陈皮的色度和气味信息,运用Pearson相关性分析探究挥发性差异成分与色度值之间的关联。结果:从陈皮及赤石脂炒陈皮中共鉴定出112个挥发性成分,其中陈皮检出成分84个、赤石脂炒陈皮检出成分97个,并筛选出α-蒎烯、β-月桂烯、芳樟醇、桧烯、罗勒烯异构体混合物、A-罗勒烯、δ-榄香烯7个差异性成分。陈皮经赤石脂炮制后明度值(L^(*))、黄蓝色值(b^(*))和总色度值(E^(*)_(ab))降低,红绿色值(a^(*))升高(P<0.01);S4、S5、S10、S13传感器响应值升高,S3、S8传感器响应值降低(P<0.05);相关性分析显示,α-蒎烯、β-月桂烯与L^(*)、E^(*)_(ab)呈负相关,与a^(*)呈正相关;桧烯与L^(*)、E^(*)_(ab)呈正相关;芳樟醇与L^(*)、E^(*)_(ab)呈正相关,与a^(*)呈负相关;罗勒烯异构体混合物与L^(*)呈正相关。结论:陈皮经赤石脂炮制后外观颜色、气味及挥发性成分均发生明显变化,α-蒎烯、β-月桂烯、桧烯、芳樟醇、A-罗勒烯等成分是赤石脂炒陈皮炮制前后挥发性成分的特征性成分,可为陈皮及其炮制品的质量评价和临床应用提供参考。 展开更多
关键词 陈皮 炮制 赤石脂 Α-蒎烯 β-月桂烯 顶空气相色谱-质谱法(hs-gc-ms) 智能感官技术
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基于电子鼻和HS-GC-MS分析茶芎酒制前后挥发性成分变化 被引量:6
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作者 张文 郑鹏 +5 位作者 张江山 肖小林 吴早丹 辛力 龚文慧 张金莲 《中国实验方剂学杂志》 北大核心 2025年第2期173-181,共9页
目的:通过比较茶芎生品与酒洗品、酒炒品挥发性成分的组成和含量差异,考察酒制对茶芎挥发性成分的影响,为茶芎及其炮制品的质量标准制订提供依据。方法:采用电子鼻识别茶芎、酒洗茶芎和酒炒茶芎的气味,联合顶空气相色谱-质谱法(HS-GC-MS... 目的:通过比较茶芎生品与酒洗品、酒炒品挥发性成分的组成和含量差异,考察酒制对茶芎挥发性成分的影响,为茶芎及其炮制品的质量标准制订提供依据。方法:采用电子鼻识别茶芎、酒洗茶芎和酒炒茶芎的气味,联合顶空气相色谱-质谱法(HS-GC-MS)检测茶芎生品及2种酒制品的挥发性成分,采用峰面积归一化法测定各成分的相对质量分数,通过SIMCA 14.1软件对所得样品数据进行主成分分析(PCA)及正交偏最小二乘法-判别分析(OPLS-DA),根据变量重要性投影(VIP)值>1筛选得到茶芎生品与酒洗茶芎和酒炒茶芎的差异性成分。结合Pearson相关性分析探究挥发性差异风味成分与电子鼻传感器之间的关联。结果:电子鼻检测结果显示,茶芎、酒洗茶芎与酒炒茶芎气味差异明显,主要涉及传感器S2、S4、S5、S6、S11、S12、S13。从茶芎及其酒制品中共鉴定出62个化合物,其中茶芎生品、酒炒茶芎、酒洗茶芎分别鉴定出46、50、51个化合物。茶芎生品与酒炒茶芎间存在21个差异性成分,经炮制后其中10个成分含量上升,11个成分含量下降;茶芎生品与酒洗茶芎之间存在20个差异性成分,经炮制后其中11个成分含量上升,9个成分含量下降;酒洗茶芎与酒炒茶芎间存在17个差异性成分,与酒洗茶芎比较,酒炒茶芎中13个成分含量上升,4个成分含量下降。苯酞类成分含量上升趋势酒洗较酒炒更明显,但总挥发性成分含量酒炒高于酒洗。相关性分析显示,电子鼻7个差异传感器与24个差异挥发性成分间存在不同程度的相关性,主要为苯酞类和烯烃类成分。结论:茶芎酒制后气味与挥发性成分含量发生了明显变化,其中正丁基苯酞、Z-正丁烯基苯酞、E-藁本内酯等成分可作为茶芎酒制前后挥发性成分的候选差异性标志物。 展开更多
关键词 茶芎 酒制 电子鼻 顶空气相色谱-质谱法(hs-gc-ms) 挥发性成分 差异性成分 相关性分析
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基于HS-GC-MS探究不同混合比例青贮饲料对羊肉挥发性物质的影响 被引量:1
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作者 宋娟娟 孙旭春 +4 位作者 陈慧丽 王春卉 栗登攀 马克岩 马友记 《畜牧兽医学报》 北大核心 2025年第7期3316-3326,共11页
旨在探究饲喂不同混合比例青贮日粮对羊肉挥发性风味物质的影响。选取18只体重相近、遗传背景一致的3月龄澳湖杂交F1代公羔,分为3组(n=6),分别为T1、T2和T3组,T1组饲喂的全株玉米和全株大豆混贮比例为8:2、T2组为7:3、T3组为6:4。饲喂6... 旨在探究饲喂不同混合比例青贮日粮对羊肉挥发性风味物质的影响。选取18只体重相近、遗传背景一致的3月龄澳湖杂交F1代公羔,分为3组(n=6),分别为T1、T2和T3组,T1组饲喂的全株玉米和全株大豆混贮比例为8:2、T2组为7:3、T3组为6:4。饲喂60 d后,采集背最长肌样本检测脂肪酸含量,并利用HS-GC-MS技术检测羊肉中挥发性物质。通过变量重要性投影(variable importance in the projection,VIP)、香气活性值(odor activity value,OAV)和挥发性物质注释风味的方法筛选羊肉关键风味物质。结果显示,T3组羊肉中单不饱和脂肪酸(monounsaturated fatty acids,MUFA)和多不饱和脂肪酸(polyunsaturated fatty acids,PUFA)均显著高于T2组(P<0.05)。在羊肉中共鉴定出290种挥发性化合物,含量由高到低依次为醛类、醇类、酮类、酯类等14类化合物。通过OAVs筛选出12种对羊肉风味有贡献的挥发性物质,其中,醛类对羊肉整体香气的贡献最大,且T3组中癸醛、辛醛、壬醛和庚醛的OAV均显著高于T1组(P<0.05)。VIP结合OAV以及挥发性物质注释风味的结果显示,辛醛、癸醛和1-辛烯-3-醇既是不同处理组的差异挥发性物质和羊肉风味的贡献者,也是产生青草味、甜味、果味、花香味等有益于羊肉风味的特征性物质。综上,辛醛、癸醛和1-辛烯-3-醇是引起饲喂不同混合比例青贮饲料羊肉风味差异的关键物质,且玉米和大豆6:4混贮(T3组)是有利于羊肉风味的最佳混贮比例。本研究揭示了玉米和大豆混合青贮饲料对羊肉风味的影响,为优化日粮组成改善羊肉风味品质提供了科学依据。 展开更多
关键词 hs-gc-ms 混合青贮 羊肉 挥发性风味物质
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基于电子鼻和HS-GC-MS技术结合STEM聚类法分析黄芪蜜炙过程中挥发性成分的动态变化
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作者 王艳 钟凌云 +7 位作者 叶焱蓉 覃祖玲 肖清蓉 谢秦 赵瑞轩 夏颖馨 李心睿 吴苏容 《中草药》 北大核心 2025年第24期8921-8931,共11页
目的 通过比较黄芪Astragali Radix生品与黄芪不同炮制程度样品之间挥发性成分的组成和含量差异,系统探究蜜炙过程中挥发性成分的动态变化规律,为蜜炙黄芪的质量标准制定及炮制工艺智能化提供依据。方法 采用电子鼻联合顶空进样-气相色... 目的 通过比较黄芪Astragali Radix生品与黄芪不同炮制程度样品之间挥发性成分的组成和含量差异,系统探究蜜炙过程中挥发性成分的动态变化规律,为蜜炙黄芪的质量标准制定及炮制工艺智能化提供依据。方法 采用电子鼻联合顶空进样-气相色谱-质谱(headspace injection-gas chromatography-mass spectrometry,HS-GC-MS)技术检测黄芪蜜炙时间节点的挥发性成分,采用峰面积归一化法测定各成分的相对质量分数,通过SIMCA 14.1软件对所得样品数据进行主成分分析(principal component analysis,PCA)及正交偏最小二乘法-判别分析(orthogonal partial least squares-discriminant analysis,OPLS-DA),根据变量重要性投影(variable importance projection,VIP)值>1且P<0.05筛选得到差异性成分;应用短时间序列表达挖掘器(short time-series expression miner,STEM)对黄芪蜜炙过程中挥发性成分进行分析。结果 电子鼻可有效区分黄芪生品及蜜炙品,且黄芪炮制前后气味差异较大。差异主要体现在传感器S1、S2、S5、S6、S10、S11(P<0.05)。从黄芪生品及黄芪蜜炙过程4个样品中共鉴定出37种挥发性成分,其中黄芪生品含20种,蜜炙15、18、21、24 min样品分别鉴定出27、20、17、18种挥发性成分,上述5个样品共有成分4种,黄芪生品与各蜜炙品的挥发性成分存在明显差异。采用STEM聚类法对各黄芪样品的挥发性成分进行分析,可将其变化趋势划分为9种类型,且在1种趋势模型中有显著性富集,其中正己醇、庚醛、α-蒎烯、α-水芹烯、2-戊基呋喃等带有特殊香气的挥发性成分随着蜜炙时间延长而降低,这些香气可能与黄芪的豆腥味有关。结论 黄芪蜜炙过程中挥发性成分类别的比例和所含物质都会随蜜炙过程的推进有所变化,大部分挥发性成分呈现较为明显的变化,其中正己醇、2,5-二羟基-6-甲基-4(H)-吡喃-4-酮、2-戊基呋喃、5-甲基糠醛等成分可作为黄芪蜜炙过程中挥发性成分的候选差异性标志物。 展开更多
关键词 黄芪 蜜炙 电子鼻 hs-gc-ms技术 挥发性成分 短时间序列表达挖掘器 正交偏最小二乘法-判别分析 主成分分析 正己醇 庚醛 Α-蒎烯 α-水芹烯 2-戊基呋喃 2 5-二羟基-6-甲基-4(H)-吡喃-4-酮 5-甲基糠醛
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基于HS-GC-MS的黄精霉变前后VOCs变化规律和关键差异成分研究 被引量:1
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作者 拱健婷 于淑琳 +6 位作者 赵艺萌 丛悦 徐媛媛 关佳莉 梁如 李莉 邹慧琴 《中医药学报》 2025年第2期37-42,共6页
目的:以黄精为研究对象,通过研究不同霉变程度下挥发性有机化合物(VOCs)的变化和关键差异成分,筛选黄精霉变的特征标志物,为黄精霉变的快速识别和中药霉变的早期预警提供科学依据。方法:在高温高湿条件下,通过人工促霉处理结合传统性状... 目的:以黄精为研究对象,通过研究不同霉变程度下挥发性有机化合物(VOCs)的变化和关键差异成分,筛选黄精霉变的特征标志物,为黄精霉变的快速识别和中药霉变的早期预警提供科学依据。方法:在高温高湿条件下,通过人工促霉处理结合传统性状鉴定法,制备不同霉变程度的黄精样品。采用顶空-气相色谱-质谱联用(HS-GC-MS)技术分析黄精样品中的主要VOCs。运用偏最小二乘判别分析(PLS-DA)和主成分分析(PCA)探讨黄精霉变前后VOCs的变化规律和关键差异。结果:从未霉变、轻微霉变、严重霉变的黄精中分别鉴定出35、33、34种成分,包括醛、醇、酮、酯、酸、烃、胺、醚及其他类成分。PLS-DA分析结果显示,不同霉变程度黄精样品之间VOCs存在显著差异,成功筛选出9个差异性成分:2-甲基丁醛、三甲胺、异戊醛、冰醋酸、正己醛、2,3-丁二醇、正戊醛、2,6-二甲基吡嗪、丙酮醛。其中,霉变后异戊醛和2,3-丁二醇含量降低,正己醛含量增加;三甲胺仅在严重霉变样品中出现;而2,6-二甲基吡嗪则仅存在于未霉变的黄精样品中。PCA分析进一步显示,正戊醛、2-甲基丁醛、正己醛、三甲胺、丙酮醛是霉变黄精的特征标志物。结论:本研究筛选出的关键差异成分可作为黄精霉变的标记物,为黄精及中药霉变的监测和质量控制提供有效手段。 展开更多
关键词 黄精 霉变 挥发性有机化合物 hs-gc-ms 偏最小二乘判别分析 主成分分析 霉变标志物
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