Objective To examine HIV self-testing uptake and its determinates among men who have sex with men （MSM） in Beijing, China. Methods A cross-sectional online survey was conducted in Beijing, China in 2016. Participant...Objective To examine HIV self-testing uptake and its determinates among men who have sex with men （MSM） in Beijing, China. Methods A cross-sectional online survey was conducted in Beijing, China in 2016. Participants were users of a popular Chinese gay networking application and had an unknown or negative HIV status. Univariate and multivariate logistic regression analyses were conducted to examine factors associated with HIV self-testing based on adjusted odds ratio （AOR） and 95% confidence interval （CI）. Results Among the 5,996 MSM included in the study, 2,383 （39.7%） reported to have used HIV self-testing kits. Willingness to use an HIV self-test kit in the future was expressed by 92% of the participants. High monthly income （AOR = 1.49; CI = 1.10-2.02; P = 0.010）, large number of male sex partners （≥2： AOR = 1.24; CI = 2.09-1.43; P = 0.002）, sexual activity with commercial male sex partners （〉 2： AOR = 1.94; CI = 1.34 -2.82; P = 0.001）, long-term drug use （AOR = 1.42; CI = 1.23-1.62; P 〈 0.001）, and long-term HIV voluntary counseling and testing （VCT） attendance （AOR = 3.62; CI = 3.11-4.22; P 〈 0.001） were all associated with increased odds of HIV self-testing uptake. Conclusion The nearly 40% rate of HIV self-testing uptake among MSM in our sample was high. In addition, an over 90% willingness to use kits in the future was encouraging. HIV self-testing could be an important solution to help China achieve the global target of having 90% of all people living with HIV diagnosed by 2020.展开更多
Background: Human Immuno-Deficiency Virus Self-Testing (HIVST) is a process where an individual who wants to know their HIV status collects a specimen, performs a test and interprets the result by themselves. HIVST da...Background: Human Immuno-Deficiency Virus Self-Testing (HIVST) is a process where an individual who wants to know their HIV status collects a specimen, performs a test and interprets the result by themselves. HIVST data from the Zimbabwe AIDS and TB Program (ATP) directorate showed that between 2019-2020, only 31% of the target HIVST kits were distributed in the country. Mashonaland West Province was one of the least performing provinces in meeting targets for HIVST kits distribution. Gaps in the implementation of the HIVST in the province ultimately affect the nationwide scaleup of targeted testing, a key enabler in achieving HIV epidemic control. We analyzed HIVST trends in Mashonaland West Province to inform HIV testing services programming. Methods: We conducted a cross-sectional study using HIVST secondary data obtained from the District Health Information Software 2 (DHIS2) electronic database. We conducted regression analysis for trends using Epi Info 7.2 and tables, bar graphs, pie charts and linear graphs were used for data presentation. Results: A total of 31,070 clients accessed HIVST kits in Mashonaland West Province from 2019-2020. A slightly higher proportion (50.4% and 51.7%) of females as compared to males accessed HIVST kits in 2019 and 2020 respectively. Overall, an increase in the trend of HIVST kits uptake was recorded (males R<sup>2</sup> = 0.3945, p-value = 0.003 and females R<sup>2</sup> = 0.4739, p-value = 0.001). There was generally a decline in the trend of community-based distribution of HIVST kits from the third quarter of 2019 throughout 2020 (R<sup>2</sup> = 0.2441, p-value = 0.006). Primary distribution of HIVST kits remained the dominant method of distribution, constituting more than half of the kits distributed in both 2019 (67%) and 2020 (86%). Conclusion: Mashonaland West Province was mainly utilising facility-based distribution model for HIVST over the community-based distribution model. We recommended training more community-based distribution agents to increase community distribution of HIVST kits.展开更多
Globally, there is increasing evidence that HIV self-testing (HIVST) is commonly practiced among health care workers (HCWs). Although HIVST kits are available in South Africa, their distribution and use remain unregul...Globally, there is increasing evidence that HIV self-testing (HIVST) is commonly practiced among health care workers (HCWs). Although HIVST kits are available in South Africa, their distribution and use remain unregulated and its acceptability, undocumented. The aim of the study was to explore the acceptability of HIV self-testing among student nurses, examine their willingness to use self-testing, and evaluate their views on the implementation of a regulated HIV self-testing programme. This was a qualitative explorative study, and six focus group discussions were conducted with 67 student nurses recruited from a private nursing college, in Pretoria, South Africa. Thematic analysis and NVivo10 qualitative software were used for data analysis. The nurses perceived HIVST as an acceptable option for HIV testing and most were willing to self-test. Self-testing will provide confidential and accessible HIV testing services, reduce the stigma associated with the condition, and increase partner testing and disclosure. HIVST is more likely to be practised if self-testing kits are easily accessible and affordable, and there are strategies to educate people before the adoption of HIVST. The lack of pre- and post-test counselling, the risk of inaccurate test results, and lack of strategies for the confirmation of self-testing results were the main arguments against HIVST. The high acceptance of HIVST among nurses suggests that HIVST is a feasible option to increase the uptake of HIV-testing among HCWs. However, pre- and post-test counselling should be considered important components in the implementation of self-testing services. Educational and awareness campaigns should precede the roll-out of the self-testing programs.展开更多
Summary What is already known about this topic?Human immunodeficiency virus(HIV)self-testing serves as a crucial strategy for overcoming testing barriers,with urine-based self-testing emerging as a potential novel app...Summary What is already known about this topic?Human immunodeficiency virus(HIV)self-testing serves as a crucial strategy for overcoming testing barriers,with urine-based self-testing emerging as a potential novel approach.What is added by this report?In a real-world setting,this study demonstrated that the urine rapid test exhibited lower diagnostic accuracy compared to the blood rapid test.Study participants expressed stronger preferences for HIV self-testing methods utilizing finger prick samples,accompanied by standard written instructions and lower costs.展开更多
目的分析湖北省部分地区2017—2022年新确证HIV-1感染者的新发感染状况及其影响因素。方法采用限制性抗原亲和力法对免疫印迹法试验结果为HIV-1抗体阳性的样本进行新发感染检测,分析判定为新近感染的样本的人口学特征,采用logistic回归...目的分析湖北省部分地区2017—2022年新确证HIV-1感染者的新发感染状况及其影响因素。方法采用限制性抗原亲和力法对免疫印迹法试验结果为HIV-1抗体阳性的样本进行新发感染检测,分析判定为新近感染的样本的人口学特征,采用logistic回归模型分析新发感染的影响因素。结果403例新确证HIV-1感染者被判定为新发感染的比例为19.11%(77/403)。新确证HIV-1感染者中以年龄≤24岁(新发感染比例为40.00%)、未婚(29.41%)、大专及以上(31.37%)、来自自愿咨询检测(Voluntary counseling and testing,VCT)门诊(40.00%)的感染者新发感染比例较高,差异有统计学意义。多因素二元logistic回归分析结果显示,年龄≤24岁(aOR=4.346,95%CI:1.342~14.075)和来自VCT门诊(aOR=6.761,95%CI:1.460~31.319)的新确证HIV-1感染者更可能为新发感染。结论湖北省部分地区近年艾滋病新发感染比例相对较低,应持续加强青少年群体艾滋病防治干预措施,推进VCT门诊建设,以实现感染者的早发现早诊治。展开更多
基金funded by China-US Collaboration on HIV/AIDS(Grant#5U2GGH001153)China National Health&Family Planning Commission(131-16-000-105-02)
文摘Objective To examine HIV self-testing uptake and its determinates among men who have sex with men （MSM） in Beijing, China. Methods A cross-sectional online survey was conducted in Beijing, China in 2016. Participants were users of a popular Chinese gay networking application and had an unknown or negative HIV status. Univariate and multivariate logistic regression analyses were conducted to examine factors associated with HIV self-testing based on adjusted odds ratio （AOR） and 95% confidence interval （CI）. Results Among the 5,996 MSM included in the study, 2,383 （39.7%） reported to have used HIV self-testing kits. Willingness to use an HIV self-test kit in the future was expressed by 92% of the participants. High monthly income （AOR = 1.49; CI = 1.10-2.02; P = 0.010）, large number of male sex partners （≥2： AOR = 1.24; CI = 2.09-1.43; P = 0.002）, sexual activity with commercial male sex partners （〉 2： AOR = 1.94; CI = 1.34 -2.82; P = 0.001）, long-term drug use （AOR = 1.42; CI = 1.23-1.62; P 〈 0.001）, and long-term HIV voluntary counseling and testing （VCT） attendance （AOR = 3.62; CI = 3.11-4.22; P 〈 0.001） were all associated with increased odds of HIV self-testing uptake. Conclusion The nearly 40% rate of HIV self-testing uptake among MSM in our sample was high. In addition, an over 90% willingness to use kits in the future was encouraging. HIV self-testing could be an important solution to help China achieve the global target of having 90% of all people living with HIV diagnosed by 2020.
文摘Background: Human Immuno-Deficiency Virus Self-Testing (HIVST) is a process where an individual who wants to know their HIV status collects a specimen, performs a test and interprets the result by themselves. HIVST data from the Zimbabwe AIDS and TB Program (ATP) directorate showed that between 2019-2020, only 31% of the target HIVST kits were distributed in the country. Mashonaland West Province was one of the least performing provinces in meeting targets for HIVST kits distribution. Gaps in the implementation of the HIVST in the province ultimately affect the nationwide scaleup of targeted testing, a key enabler in achieving HIV epidemic control. We analyzed HIVST trends in Mashonaland West Province to inform HIV testing services programming. Methods: We conducted a cross-sectional study using HIVST secondary data obtained from the District Health Information Software 2 (DHIS2) electronic database. We conducted regression analysis for trends using Epi Info 7.2 and tables, bar graphs, pie charts and linear graphs were used for data presentation. Results: A total of 31,070 clients accessed HIVST kits in Mashonaland West Province from 2019-2020. A slightly higher proportion (50.4% and 51.7%) of females as compared to males accessed HIVST kits in 2019 and 2020 respectively. Overall, an increase in the trend of HIVST kits uptake was recorded (males R<sup>2</sup> = 0.3945, p-value = 0.003 and females R<sup>2</sup> = 0.4739, p-value = 0.001). There was generally a decline in the trend of community-based distribution of HIVST kits from the third quarter of 2019 throughout 2020 (R<sup>2</sup> = 0.2441, p-value = 0.006). Primary distribution of HIVST kits remained the dominant method of distribution, constituting more than half of the kits distributed in both 2019 (67%) and 2020 (86%). Conclusion: Mashonaland West Province was mainly utilising facility-based distribution model for HIVST over the community-based distribution model. We recommended training more community-based distribution agents to increase community distribution of HIVST kits.
文摘Globally, there is increasing evidence that HIV self-testing (HIVST) is commonly practiced among health care workers (HCWs). Although HIVST kits are available in South Africa, their distribution and use remain unregulated and its acceptability, undocumented. The aim of the study was to explore the acceptability of HIV self-testing among student nurses, examine their willingness to use self-testing, and evaluate their views on the implementation of a regulated HIV self-testing programme. This was a qualitative explorative study, and six focus group discussions were conducted with 67 student nurses recruited from a private nursing college, in Pretoria, South Africa. Thematic analysis and NVivo10 qualitative software were used for data analysis. The nurses perceived HIVST as an acceptable option for HIV testing and most were willing to self-test. Self-testing will provide confidential and accessible HIV testing services, reduce the stigma associated with the condition, and increase partner testing and disclosure. HIVST is more likely to be practised if self-testing kits are easily accessible and affordable, and there are strategies to educate people before the adoption of HIVST. The lack of pre- and post-test counselling, the risk of inaccurate test results, and lack of strategies for the confirmation of self-testing results were the main arguments against HIVST. The high acceptance of HIVST among nurses suggests that HIVST is a feasible option to increase the uptake of HIV-testing among HCWs. However, pre- and post-test counselling should be considered important components in the implementation of self-testing services. Educational and awareness campaigns should precede the roll-out of the self-testing programs.
基金Supported by the National Natural Science Foundation of China(grant numbers#71974212,#71774178,#81803334,#72204059)the Guangdong Basic and Applied Basic Research Foundation(grant number#2020A1515010737)+1 种基金the Science and Technology Program of Guangzhou,China(grant number#202201010078)the Infectious Disease Prevention and Control of the National Science and Technology Major Project(grant number#2018ZX10715004).
文摘Summary What is already known about this topic?Human immunodeficiency virus(HIV)self-testing serves as a crucial strategy for overcoming testing barriers,with urine-based self-testing emerging as a potential novel approach.What is added by this report?In a real-world setting,this study demonstrated that the urine rapid test exhibited lower diagnostic accuracy compared to the blood rapid test.Study participants expressed stronger preferences for HIV self-testing methods utilizing finger prick samples,accompanied by standard written instructions and lower costs.
文摘目的分析湖北省部分地区2017—2022年新确证HIV-1感染者的新发感染状况及其影响因素。方法采用限制性抗原亲和力法对免疫印迹法试验结果为HIV-1抗体阳性的样本进行新发感染检测,分析判定为新近感染的样本的人口学特征,采用logistic回归模型分析新发感染的影响因素。结果403例新确证HIV-1感染者被判定为新发感染的比例为19.11%(77/403)。新确证HIV-1感染者中以年龄≤24岁(新发感染比例为40.00%)、未婚(29.41%)、大专及以上(31.37%)、来自自愿咨询检测(Voluntary counseling and testing,VCT)门诊(40.00%)的感染者新发感染比例较高,差异有统计学意义。多因素二元logistic回归分析结果显示,年龄≤24岁(aOR=4.346,95%CI:1.342~14.075)和来自VCT门诊(aOR=6.761,95%CI:1.460~31.319)的新确证HIV-1感染者更可能为新发感染。结论湖北省部分地区近年艾滋病新发感染比例相对较低,应持续加强青少年群体艾滋病防治干预措施,推进VCT门诊建设,以实现感染者的早发现早诊治。
