In Tunisia and particularly in Monastir region, groundwater constitutes the main source of water supply systems. A lot of problems are facing the water management authorities. In fact, the Moknine coastal aquifer high...In Tunisia and particularly in Monastir region, groundwater constitutes the main source of water supply systems. A lot of problems are facing the water management authorities. In fact, the Moknine coastal aquifer highlights several qualitative and quantitative anomalies due to the irrigated perimeters extension (Teboulba, Bekalta), releases of harmful products from the textile industry (Ksar Hellal and Moknine), intense overexploitation and seawater intrusion. Thus, for groundwater resources management, a Decision Support System (DSS) is developed for the Monastir region. This Decision Support System (DSS) brings together, on a digital support, the data descriptive and graphical component for groundwater management. It is a hydrogeological relational database joined with a Hydrogeological Information System for the Monastir region (HISM) which enables fast and effective processing of large volumes of spatial data from multiple sources. The implementation of the Hydrogeological Information System is assured using Object-Oriented Programming (OOP). The “Unified Modeling Language” (UML) is an Object-Oriented Design (OOD) methodology which is choiced for data modeling. The application interfaces have been developed in Visual Basic (VB.net) within the Integrated Development Environment (IDE) from Microsoft Visual Studio. “DotSpatial” library integrated is used to manage the geographic information layers. The HISM contains thematic layers acquired through the vectorization of 22 topographic and geologic maps (1/50,000 and 1/25,000) and the input of descriptive data from water well and pollution sources from field and laboratory studies. The HISM has a great management capacity;it ensures the conversion from the geographic coordinates to the planimetric coordinates. It allows adding, modifying, deleting and editing data (Rainfall, piezometric and geochemical). It also ensures the storage and editing of the digitized and/or generated cartographic database. This DSS was applied to the superficial coastal aquifer system of Moknine to define a conceptual model of groundwater functioning and assessment vulnerability to seawater intrusion.展开更多
A problem of evolution of high-grade polymeta- morphic terrain appeared in last decades:in worldwide complexes the identification of true stages of polymetamorphism encounters a problem of zircon zoning(or garnet etc....A problem of evolution of high-grade polymeta- morphic terrain appeared in last decades:in worldwide complexes the identification of true stages of polymetamorphism encounters a problem of zircon zoning(or garnet etc.)that is the function of fluid activity and therefore the newly formed zone can not always be recorded.Structural geology allows discriminating between different stages of metamor-展开更多
目的探讨CD14启动子-159位点C/T多态性对健康青年血脂比值的影响及在高糖低脂(highcarbohydrate/low fat,HC/LF)膳食诱导的血脂比值变化中的作用。方法纳入56名(22.89±1.80岁)健康青年志愿者,先后给予7d平衡膳食和6dHC/LF膳食,于...目的探讨CD14启动子-159位点C/T多态性对健康青年血脂比值的影响及在高糖低脂(highcarbohydrate/low fat,HC/LF)膳食诱导的血脂比值变化中的作用。方法纳入56名(22.89±1.80岁)健康青年志愿者,先后给予7d平衡膳食和6dHC/LF膳食,于第1d、第8d及第14d清晨抽取12h空腹静脉血,测定血脂水平,计算甘油三酯/高密度脂蛋白胆固醇(triglyceride/high density lipoprotein-cholesterol,TG/HDL-c)、log(TG/HDL-c)、总胆固醇/高密度脂蛋白胆固醇(total cholesterol/high density lipoprotein-cholesterol,TC/HDL-c)和低密度脂蛋白胆固醇/高密度脂蛋白胆固醇(low density lipoprotein-cholesterol/high density lipoprotein-cholesterol,LDL-c/HDL-c)。提取基因组DNA,聚合酶链反应-限制性酶切法分析CD14启动子-159位点多态性。结果女性TT纯合子受试者TG/HDL-c(P<0.05),log(TG/HDL-c)(P<0.05)和LDL-c/HDL-c(P<0.05)基础值高于C等位基因携带者,男性C等位基因携带者TG/HDL-c(P<0.05)、log(TG/HDL-c)(P<0.001)和TC/HDL-c(P<0.01)高于女性。HC/LF膳食前,女性TT纯合子受试者TG/HDL-c(P<0.01)、log(TG/HDL-c)(P<0.001)和TC/HDL-c(P<0.05)均高于C等位基因携带者,男性C等位基因携带者4种血脂比值均高于女性(P<0.05)。HC/LF膳食后,女性TT纯合子受试者TG/HDL-c(P<0.05)、log(TG/HDL-c)(P<0.05)和LDL-c/HDL-c(P<0.05)均高于C等位基因携带者,男性C等位基因携带者TG/HDL-c(P<0.05)、log(TG/HDL-c)(P<0.01)高于女性。与HC/LF膳食前相比,HC/LF膳食后男性C等位基因携带者TC/HDL-c(P<0.001)、LDL-c/HDL-c(P<0.01)降低,TT纯合子受试者TC/HDL-c(P<0.001)降低。HC/LF膳食后女性C等位基因携带者TG/HDL-c(P<0.05)、log(TG/HDL-c)(P<0.05)升高,TC/HDL-c(P<0.001)、LDL-c/HDL-c(P<0.01)降低,TT纯合子受试者只有TC/HDL-c(P<0.01)降低。结论相较于T等位基因携带者,C等位基因携带者中,膳食改变对血脂表型的作用是微效,可能被CD14-159位点C等位基因掩盖。HC/LF膳食与CD14-159位点C等位基因的相互作用能够降低青年男女LDL-c/HDL-c,升高女性TG/HDL-c和log(TG/HDL-c)。展开更多
文摘In Tunisia and particularly in Monastir region, groundwater constitutes the main source of water supply systems. A lot of problems are facing the water management authorities. In fact, the Moknine coastal aquifer highlights several qualitative and quantitative anomalies due to the irrigated perimeters extension (Teboulba, Bekalta), releases of harmful products from the textile industry (Ksar Hellal and Moknine), intense overexploitation and seawater intrusion. Thus, for groundwater resources management, a Decision Support System (DSS) is developed for the Monastir region. This Decision Support System (DSS) brings together, on a digital support, the data descriptive and graphical component for groundwater management. It is a hydrogeological relational database joined with a Hydrogeological Information System for the Monastir region (HISM) which enables fast and effective processing of large volumes of spatial data from multiple sources. The implementation of the Hydrogeological Information System is assured using Object-Oriented Programming (OOP). The “Unified Modeling Language” (UML) is an Object-Oriented Design (OOD) methodology which is choiced for data modeling. The application interfaces have been developed in Visual Basic (VB.net) within the Integrated Development Environment (IDE) from Microsoft Visual Studio. “DotSpatial” library integrated is used to manage the geographic information layers. The HISM contains thematic layers acquired through the vectorization of 22 topographic and geologic maps (1/50,000 and 1/25,000) and the input of descriptive data from water well and pollution sources from field and laboratory studies. The HISM has a great management capacity;it ensures the conversion from the geographic coordinates to the planimetric coordinates. It allows adding, modifying, deleting and editing data (Rainfall, piezometric and geochemical). It also ensures the storage and editing of the digitized and/or generated cartographic database. This DSS was applied to the superficial coastal aquifer system of Moknine to define a conceptual model of groundwater functioning and assessment vulnerability to seawater intrusion.
文摘A problem of evolution of high-grade polymeta- morphic terrain appeared in last decades:in worldwide complexes the identification of true stages of polymetamorphism encounters a problem of zircon zoning(or garnet etc.)that is the function of fluid activity and therefore the newly formed zone can not always be recorded.Structural geology allows discriminating between different stages of metamor-
文摘目的探讨CD14启动子-159位点C/T多态性对健康青年血脂比值的影响及在高糖低脂(highcarbohydrate/low fat,HC/LF)膳食诱导的血脂比值变化中的作用。方法纳入56名(22.89±1.80岁)健康青年志愿者,先后给予7d平衡膳食和6dHC/LF膳食,于第1d、第8d及第14d清晨抽取12h空腹静脉血,测定血脂水平,计算甘油三酯/高密度脂蛋白胆固醇(triglyceride/high density lipoprotein-cholesterol,TG/HDL-c)、log(TG/HDL-c)、总胆固醇/高密度脂蛋白胆固醇(total cholesterol/high density lipoprotein-cholesterol,TC/HDL-c)和低密度脂蛋白胆固醇/高密度脂蛋白胆固醇(low density lipoprotein-cholesterol/high density lipoprotein-cholesterol,LDL-c/HDL-c)。提取基因组DNA,聚合酶链反应-限制性酶切法分析CD14启动子-159位点多态性。结果女性TT纯合子受试者TG/HDL-c(P<0.05),log(TG/HDL-c)(P<0.05)和LDL-c/HDL-c(P<0.05)基础值高于C等位基因携带者,男性C等位基因携带者TG/HDL-c(P<0.05)、log(TG/HDL-c)(P<0.001)和TC/HDL-c(P<0.01)高于女性。HC/LF膳食前,女性TT纯合子受试者TG/HDL-c(P<0.01)、log(TG/HDL-c)(P<0.001)和TC/HDL-c(P<0.05)均高于C等位基因携带者,男性C等位基因携带者4种血脂比值均高于女性(P<0.05)。HC/LF膳食后,女性TT纯合子受试者TG/HDL-c(P<0.05)、log(TG/HDL-c)(P<0.05)和LDL-c/HDL-c(P<0.05)均高于C等位基因携带者,男性C等位基因携带者TG/HDL-c(P<0.05)、log(TG/HDL-c)(P<0.01)高于女性。与HC/LF膳食前相比,HC/LF膳食后男性C等位基因携带者TC/HDL-c(P<0.001)、LDL-c/HDL-c(P<0.01)降低,TT纯合子受试者TC/HDL-c(P<0.001)降低。HC/LF膳食后女性C等位基因携带者TG/HDL-c(P<0.05)、log(TG/HDL-c)(P<0.05)升高,TC/HDL-c(P<0.001)、LDL-c/HDL-c(P<0.01)降低,TT纯合子受试者只有TC/HDL-c(P<0.01)降低。结论相较于T等位基因携带者,C等位基因携带者中,膳食改变对血脂表型的作用是微效,可能被CD14-159位点C等位基因掩盖。HC/LF膳食与CD14-159位点C等位基因的相互作用能够降低青年男女LDL-c/HDL-c,升高女性TG/HDL-c和log(TG/HDL-c)。
