Objective:To discuss the effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section. Methods:70 patients with postpar...Objective:To discuss the effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section. Methods:70 patients with postpartum hemorrhage after placenta previa cesarean section who were treated in Chengdu Women & Children's Central Hospital between January 2014 and February 2017 were collected and then divided into the control group (n=35) who received uterine packing therapy and the observation group (n=35) who received Hemabate combined with packing therapy according to random number table. Serum levels of oxidative stress indexes and stress hormones immediately after operation and 24 h after operation were compared between two groups of patients.Results: Immediately after operation and 24 h after operation, serum oxidative stress indexes ROS and MDA levels of observation group were significantly lower than those of control group while SOD, GSH-px and CAT levels were significantly higher than those of control group, and serum stress hormones NE, E and Cor levels were significantly lower than those of control group.Conclusion: Hemabate combined with packing therapy can effectively reduce systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section, is a more ideal way of the bleeding.展开更多
Objective: to study and analyze the clinical effect of postpartum hemorrhage by using Xinmopei. Methods: a total of 60 patients were diagnosed with postpartum hemorrhage in the obstetrics and gynecology department for...Objective: to study and analyze the clinical effect of postpartum hemorrhage by using Xinmopei. Methods: a total of 60 patients were diagnosed with postpartum hemorrhage in the obstetrics and gynecology department for nearly two months, and these patients were randomly divided into two groups, with 30 patients each in the control and intervention groups. The patients in the intervention group used the postpartum hemorrhage with uterine muscle to deal with the postpartum hemorrhage. The total amount of each infusion was about 250ug. When the puerpera had multiple massive bleeding, the remediation could be implemented, while the control group implemented conventional hemostasis measures. The patient side reactions were observed after administering the patient, and the maternal bleeding volume, efficacy, adverse reactions and the patient satisfaction during the process were recorded. Conclusion: the number of patients in the postpartum bleeding group was significantly less than that in the control group, with different statistical significance (P <0.05).Using conventional hemostatic muscle treatment measures of patients in 13 cases, 9 cases, failure 8 cases, total high efficiency of 73.3%, muscle injection of postpartum bleeding group patients 15 cases, 14 cases, failure 1 case, total high efficiency of 96.7%, the two groups effect has different statistical significance (P <0.05).Comparing the results of the incidence of two serious adverse reactions, the overall incidence of the control group was 13.33%, and the overall incidence of uterine muscular injection was 30%, which was statistically significant (P <0.05).After remission, all diseases have resolved within one day. In the patient satisfaction survey, we showed that the control group was 73.3% satisfied with the treatment effect of medical workers and 96.7% satisfied with the method of uterine muscle perfusion. The difference between the two effects was of great statistical value (P <0.05).Conclusion: the use of hemabate is safe and reliable to handling postpartum bleeding, so it is very worth popularizing and using in medical practice.展开更多
基金Special Funds of Natural Science Foundation of China No:2016YFC1000406.
文摘Objective:To discuss the effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section. Methods:70 patients with postpartum hemorrhage after placenta previa cesarean section who were treated in Chengdu Women & Children's Central Hospital between January 2014 and February 2017 were collected and then divided into the control group (n=35) who received uterine packing therapy and the observation group (n=35) who received Hemabate combined with packing therapy according to random number table. Serum levels of oxidative stress indexes and stress hormones immediately after operation and 24 h after operation were compared between two groups of patients.Results: Immediately after operation and 24 h after operation, serum oxidative stress indexes ROS and MDA levels of observation group were significantly lower than those of control group while SOD, GSH-px and CAT levels were significantly higher than those of control group, and serum stress hormones NE, E and Cor levels were significantly lower than those of control group.Conclusion: Hemabate combined with packing therapy can effectively reduce systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section, is a more ideal way of the bleeding.
文摘Objective: to study and analyze the clinical effect of postpartum hemorrhage by using Xinmopei. Methods: a total of 60 patients were diagnosed with postpartum hemorrhage in the obstetrics and gynecology department for nearly two months, and these patients were randomly divided into two groups, with 30 patients each in the control and intervention groups. The patients in the intervention group used the postpartum hemorrhage with uterine muscle to deal with the postpartum hemorrhage. The total amount of each infusion was about 250ug. When the puerpera had multiple massive bleeding, the remediation could be implemented, while the control group implemented conventional hemostasis measures. The patient side reactions were observed after administering the patient, and the maternal bleeding volume, efficacy, adverse reactions and the patient satisfaction during the process were recorded. Conclusion: the number of patients in the postpartum bleeding group was significantly less than that in the control group, with different statistical significance (P <0.05).Using conventional hemostatic muscle treatment measures of patients in 13 cases, 9 cases, failure 8 cases, total high efficiency of 73.3%, muscle injection of postpartum bleeding group patients 15 cases, 14 cases, failure 1 case, total high efficiency of 96.7%, the two groups effect has different statistical significance (P <0.05).Comparing the results of the incidence of two serious adverse reactions, the overall incidence of the control group was 13.33%, and the overall incidence of uterine muscular injection was 30%, which was statistically significant (P <0.05).After remission, all diseases have resolved within one day. In the patient satisfaction survey, we showed that the control group was 73.3% satisfied with the treatment effect of medical workers and 96.7% satisfied with the method of uterine muscle perfusion. The difference between the two effects was of great statistical value (P <0.05).Conclusion: the use of hemabate is safe and reliable to handling postpartum bleeding, so it is very worth popularizing and using in medical practice.
