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Numerical Studies on Thermal and Hydrodynamic Characteristics of LNG in Helically Coiled Tube-in-Tube Heat Exchangers
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作者 Fayi Yan Xuejian Pei +1 位作者 He Lu Shuzhen Zong 《Frontiers in Heat and Mass Transfer》 EI 2024年第1期287-304,共18页
As compact and efficient heat exchange equipment,helically coiled tube-in-tube heat exchangers(HCTT heat exchangers)are widely used in many industrial processes.However,the thermal-hydraulic research of liquefied natu... As compact and efficient heat exchange equipment,helically coiled tube-in-tube heat exchangers(HCTT heat exchangers)are widely used in many industrial processes.However,the thermal-hydraulic research of liquefied natural gas(LNG)as the working fluid inHCTT heat exchangers is rarely reported.In this paper,the characteristics of HCTT heat exchangers,in which LNG flows in the inner tube and ethylene glycol-water solution flows in the outer tube,are studied by numerical simulations.The influences of heat transfer characteristics and pressure drops of the HCTT heat transfers are studied by changing the initial flow velocity,the helical middle diameter,and the helical pitch.The results indicate that different initial flow velocities in the inner tube and the outer tube of the HCTT heat exchanger have little influence on the secondary flow of the fluid in the helical tubes,and the overall flow characteristics tend to be stable.The smaller helical middle diameter of the HCTT heat exchanger leads to the shorter fluid flow length,the smaller resistance along the tubes and the increase of initial pressure under the condition of constant inlet velocity,which promotes the occurrence of secondary flow.The axial flow of fluid promotes the destruction of heat transfer boundary layer and gains strength of the turbulence and heat transfer efficiency.With the increase of the helical pitch of the HCTT heat exchanger,the turbulent intensity and the heat transfer efficiency are also increased.Moreover,the improvement of the flow state of the HCTT exchanger in a longer helical pitch also enhances the heat exchange efficiency. 展开更多
关键词 hctt heat exchanger LNG helically coil heat transfer coefficient pressure drop
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新疆阿魏树脂不同分离部位对结肠癌细胞HCT116的抑制作用 被引量:8
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作者 周龙龙 张海英 +1 位作者 任燕 周倩 《中国实验方剂学杂志》 CAS 北大核心 2013年第23期183-186,共4页
目的:分析新疆阿魏树脂不同分离部位对结肠癌细胞HCT116抑制作用的活性,并确定其有效活性部位。方法:通过磺酰罗丹明B比色法(SRB)与流式细胞术以细胞密度1×105个mL,药物质量浓度250,125,62.5,31.25,15.6 mg·L-1(流式细胞术药... 目的:分析新疆阿魏树脂不同分离部位对结肠癌细胞HCT116抑制作用的活性,并确定其有效活性部位。方法:通过磺酰罗丹明B比色法(SRB)与流式细胞术以细胞密度1×105个mL,药物质量浓度250,125,62.5,31.25,15.6 mg·L-1(流式细胞术药物浓度为62.5 mg·L-1),检测新疆阿魏树脂不同分离部位(石油醚部位、乙酸乙酯部位,甲醇部位)对结肠癌细胞HCT116药物作用24 h后的增殖抑制与凋亡作用,以IC50和总凋亡率作为指标衡量其各分离部位抑制肿瘤的活性效能。结果:石油醚部位:对结肠癌细胞HCT116增殖抑制IC5068.7 mg·L-1,总凋亡率为(43.4±1.1)%;乙酸乙酯部位:IC5043.7 mg·L-1,总凋亡率为(56.2±0.9)%;甲醇部位:IC5059.6 mg·L-1,总凋亡率为(46.7±3.1)%。结论:新疆阿魏树脂乙醇提取物的乙酸乙酯萃取部位对结肠癌细胞HCT116细胞毒性作用较强并能促进其大量凋亡,初步确定为新疆阿魏树脂抗肿瘤活性部位。 展开更多
关键词 新疆阿魏 结肠癌hctt116细胞 磺酰罗丹明B比色法 细胞凋亡 抗肿瘤活性
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