According to the distribution of high fluoride\|bearing groundwater in Liaoning Province, China, the cause of formation and hydrogeochemical characteristics as well as its relationship with human health and illness r...According to the distribution of high fluoride\|bearing groundwater in Liaoning Province, China, the cause of formation and hydrogeochemical characteristics as well as its relationship with human health and illness rate were discussed. Strategies to prevent and control fluoride pollution have also been outlined.展开更多
A theory of seepage instability was used to estimate the harmfulness of water-inrush from a coal seam floor in a particular coal mine of the Mining Group,Xuzhou. Based on the stratum column chart in this coal mine,the...A theory of seepage instability was used to estimate the harmfulness of water-inrush from a coal seam floor in a particular coal mine of the Mining Group,Xuzhou. Based on the stratum column chart in this coal mine,the distribu-tion of stress in mining floors when the long-wall mining was respectively pushed along to 100 m and to 150 m was simulated by using the numerical software (RFPA2D). The permeability parameters of the coal seam floor are described given the relationship between permeability parameters. Strain and the water-inrush-indices were calculated. The wa-ter-inrush-index was 67.2% when the working face was pushed to 100 m,showing that water-inrush is possible and it was 1630% when the working face was pushed to 150 m,showing that water-inrush is quite probable. The results show that as long-wall mining is pushed along,the failure zone is enlarged,the strain increased,and fissures developed cor-respondingly,resulting in the formation of water-inrush channels. Accompanied by the failure of the strata,the perme-ability increased exponentially. In contrast,the non-Darcy flow β factor and the acceleration coefficient decreased ex-ponentially,while the increase in the water-inrush-index was nearly exponential and the harmfulness of water-inrush in the coal mine increased accordingly.展开更多
A new report from Jeanologia highlights theurgent need for the denim industry to adopt saferalternatives to harmful chemicals.The study alsostresses reducing excessive water use in garmentfinishing.The report,compiled...A new report from Jeanologia highlights theurgent need for the denim industry to adopt saferalternatives to harmful chemicals.The study alsostresses reducing excessive water use in garmentfinishing.The report,compiled in 2024,analyzed datafrom more than ll5,000 dentm finishing processes.lt found that 24%of denim finishing processes stilluse hazardous chemicals,posing risks to both theenvironment and the health of workers.展开更多
This research study fabrics to ensure that they are free from carcinogenic dyes. It has been observed that there are poor-quality fabrics and consumers go to buy them without paying attention to the risks of using pro...This research study fabrics to ensure that they are free from carcinogenic dyes. It has been observed that there are poor-quality fabrics and consumers go to buy them without paying attention to the risks of using prohibited materials in the manufacture of these fabrics, and the use of unknown dyes has proven that some of them cause diseases to humans, especially children, that cause cancerous diseases. With the study sample consisting of (7), the study results indicate the presence of toxic formaldehyde in all sample dyes obtained from discount markets and online shopping.展开更多
Sulfuric acid slag,a common byproduct with high iron content,poses challenges due to its high levels of harmful impurities and is often discarded as solid waste,leading to significant environmental and water pollution...Sulfuric acid slag,a common byproduct with high iron content,poses challenges due to its high levels of harmful impurities and is often discarded as solid waste,leading to significant environmental and water pollution.To address this issue and improve resource utilization,the preparation process of oxidized pellets from sulfuric acid slag was studied,exploring suitable pelletizing systems and thermal parameters.Additionally,the removal of harmful elements and the consolidation mechanism were established during the oxidation roasting process.The findings revealed that sulfuric acid slag along with specific processing conditions,such as using two high-pressure grinding rolls and adding 1.25 wt.%bentonite,resulted in the production of qualified green pellets with desirable physical properties.Through a thermal treatment process involving preheating and roasting,the desulfurization rate of the pellets reached 95.55%and the removal efficiency of arsenic achieved 27.11%.Hematite recrystallizes,shrinks,and forms a reticulated structure with Fe2O3 recrystallization as the backbone,resulting in higher consolidation strength.展开更多
Environmental pollution,which has spread across cities and villages,is doing severe harm to both nature and humans.Rivers once clear are now dirty,making fish die,while the air we breathe is filled with harmful gases ...Environmental pollution,which has spread across cities and villages,is doing severe harm to both nature and humans.Rivers once clear are now dirty,making fish die,while the air we breathe is filled with harmful gases that damage our health.This situation has aroused great concern among people of all ages,as no one can escape its effects.展开更多
The annual average number of snowstorm days in Tongliao area is 1-3 d.Snowstorms mainly happen from October to next May,peaking from December to next March.The incidence is the highest between 12:00 and 15:00.The Mong...The annual average number of snowstorm days in Tongliao area is 1-3 d.Snowstorms mainly happen from October to next May,peaking from December to next March.The incidence is the highest between 12:00 and 15:00.The Mongolian low vortex is the main weather system that triggers snowstorms,and can be classified into three types:small trough development,horizontal trough becoming vertical,and low trough moving eastwards.Snowstorms pose a relatively serious threat to agricultural and animal husbandry production,transportation,power and communication in Tongliao.Especially in spring,snowstorm weather poses a greater threat to agriculture and animal husbandry in Tongliao.It is needed to pay attention to the impact of extreme weather and climate events such as snowstorms,strengthen research on the mechanisms of disaster-causing weather,enhance the early warning capability of disasters,and provide good service guarantees for low-temperature weather in winter.展开更多
Suitable temperature and light intensity play important roles in the formation of harmful algae blooms(HABs),which can pose serious threats to aquatic ecosystems and human health.In this study,we measured the growth,p...Suitable temperature and light intensity play important roles in the formation of harmful algae blooms(HABs),which can pose serious threats to aquatic ecosystems and human health.In this study,we measured the growth,physiological function,and paralytic shellfish toxins(PSTs)production of Alexandrium pacificum(CCMA-272),a strain isolated from East China Sea,at different temperatures(15,20,and 25℃)and light intensities(30,60,and 90μmol photons/(m^(2)·s)).Results indicate that temperature and light intensity significantly affected the growth,physiology,and toxigenic potentials of A.pacificum.The optimal conditions for the growth of A.pacificum were observed at 20℃ under60μmol photons/(m^(2)·s).Regarding the production of PSTs,this strain of A.pacificum produced 12 PSTs,including carbamate toxins:saxitoxin(STX),neosaxitoxin(NEO),and gonyautoxin 1–4(GTX1,GTX2,GTX3,GTX4);dicarbamoyl toxins:dicarbamoylsaxitoxin(dcSTX),dicarbamoylgonyautoxin 2,3(dcGTX2,dcGTX3);and N-sulfocarbamoyl toxins:N-sulfocarbamoylgonyautoxin 1,2(C1,C2),and gonyautoxin 5(GTX5).Among all the PSTs,C2 was the most abundant.Low temperature(15℃)and high light intensity(90μmol photons/(m^(2)·s))were beneficial for the production of PSTs in A.pacificum.When cultured at 20 and 25℃,A.pacificum generated comparable total quantities of PSTs,yet the toxicity levels were lower at 25℃.Intra-cellular PSTs contents were greater than extra-cellular PSTs contents,except those under the condition of 25℃ with 30μmol photons/(m^(2)·s).However,as the increase of temperature,A.pacificum released more amounts of analogues with higher toxicity levels(e.g.,STX and dcGTX_(2))into the environment than intracellularly.These findings emphasize the significant sensitivity of A.pacificum to temperature and light intensity,highlighting the importance of evaluating both intra-cellular and extra-cellular PSTs for assessing its toxicity and aiding in the prediction and management of HABs.展开更多
Hypophosphatasia(HPP)is a rare metabolic bone disorder often misdiagnosed as fibromyalgia due to overlapping symptoms such as chronic pain,fatigue,and muscle weakness.This diagnostic error disproportionately affects w...Hypophosphatasia(HPP)is a rare metabolic bone disorder often misdiagnosed as fibromyalgia due to overlapping symptoms such as chronic pain,fatigue,and muscle weakness.This diagnostic error disproportionately affects women and can result in significant psychological distress due to repeated dismissal of symptoms.Despite low serum alkaline phosphatase(ALP)being a key biochemical clue to HPP,it is frequently overlooked in standard diagnostic evaluations.Consequen-tly,many patients endure years of ineffective treatment,invalidation,and worse-ning psychiatric outcomes.This editorial emphasizes the need for greater clinical vigilance in distinguishing HPP from fibromyalgia,particularly when features such as chronic pain,premature tooth loss,and persistently low ALP are present.Gender biases in pain diagnosis further compound this problem,leading to gr-eater misdiagnosis rates among women and contributing to the erosion of trust in medical care.The psychiatric consequences of diagnostic delays are substantial,with affected individuals experiencing elevated rates of depression,anxiety,and emotional distress.Greater recognition of low ALP as a meaningful diagnostic clue may enhance diagnostic accuracy,improve patient outcomes,and reduce the psychological toll of misdiagnosis.展开更多
Pueraria montana is a perennial twining vine species of Pueraria in Leguminosae.Because of its fast growth and strong climbing and covering ability,this species has the potential threat of invading forest ecosystem.Ba...Pueraria montana is a perennial twining vine species of Pueraria in Leguminosae.Because of its fast growth and strong climbing and covering ability,this species has the potential threat of invading forest ecosystem.Based on the investigation of the occurrence and harm of P.montana in the"four mountains"forest ecosystem in the central urban area of Chongqing,combined with its growth habits and biological characteristics,we comprehensively evaluated its harm risk.The results show that P.montana is widely distributed in the forest ecosystem within the"four mountains"in the central urban area of Chongqing.On average,there was a distribution site of P.montana every 1.38 km of forest road with a scale of 0.43 hm 2/survey point and a coverage of about 42.86%.P.montana mainly occupy forest land by covering and climbing,threatening the original vegetation of forest land.It grows rapidly,and its ability of diffusion and colonization is very strong.The average length of new branches was 11.52 m/year,and the number of effective tillers was 5.25.According to National Forestry Pest Risk Analysis Index System,the risk assessment value of P.montana was 2.51,so it is a medium-risk harmful plant to forestry.It is suggested that the forestry department should strengthen the management of P.montana to prevent its further spread.展开更多
The blooms of Alexandrium catenella are a long-outstanding issue in the world,causing severe impacts on the local marine environment and the aquaculture industry.Our previous studies have also shown that mango peel ex...The blooms of Alexandrium catenella are a long-outstanding issue in the world,causing severe impacts on the local marine environment and the aquaculture industry.Our previous studies have also shown that mango peel extracts(MPE)could effectively inhibit the growth of A.catenella under controlled laboratory conditions.However,it remains unknown whether using MPE to control A.catenella-induced harmful algal blooms(HABs)in aquaculture environments will cause the release of intracellular phycotoxins into the surrounding environment,potentially affecting aquatic organisms.Additionally,the potential impact of MPE itself on aquatic life is another concern.The objective of this study was to clarify these issues primarily by assessing the ecological safety of MPE.The intracellular and extracellular paralytic shellfish toxins(PSTs)contents of A.catenella was measured throughout the experimental period using liquid chromatography tandem time-of-flight mass spectrometry(LC-TOFMS).The results showed that MPE reduced the PSTs contents in A.catenella,while no significant fluctuation was observed in the extracellular PSTs contents.Meanwhile,MPE exhibited varying degrees of inhibitory effects on the four HABs species selected in this study but promoted the growth of three of the four bait algae.The recorded results regarding the survival rate,water clearance rate,and growth rate of aquatic organism exposed to MPE showed no significant different between the control group and the experimental group.This study clarified that using MPE to govern HABs in aquaculture environments would not affect the growth of cultured organisms and demonstrated that MPE has species-specific antialgal properties.These findings contribute to a better understanding of the potential of MPE as an algaecide.展开更多
Smoking increases complications and mortality in people with diabetes.Quitting delivers major benefits,but physiological(weight gain,insulin sensitivity shifts)and psychological barriers make cessation harder in this ...Smoking increases complications and mortality in people with diabetes.Quitting delivers major benefits,but physiological(weight gain,insulin sensitivity shifts)and psychological barriers make cessation harder in this group.Our review article examined strategies tailored to people with diabetes.All smokers with diabetes should receive clear,personalized advice to quit,embedded in routine care.Among the available medications,varenicline has the strongest evidence in this population.Nicotine replacement therapy and bupropion may help but have limited diabetes-specific data,so they should be used with caution.Tobacco harm reduction(e-cigarettes,heated tobacco products)may facilitate switching away from combustible cigarettes and reduce exposure,although the long-term safety and efficacy in diabetes remain uncertain.Glucagon-like peptide-1 receptor agonists can aid weight and glycemic control and may indirectly support cessation.Digital tools(apps,wearables,and remote monitoring)offer real-time support and adherence tracking,although diabetes-specific effectiveness is still being established.Smoking cessation in people with diabetes requires urgent attention.Evidence-based interventions should be integrated into routine care,with particular attention given to early monitoring of glucose,body weight,and blood pressure after quitting,plus structured follow-up.More research should develop and test tailored,longterm strategies for this high-risk group,including pragmatic trials integrating harm reduction and digital support.展开更多
Harmful algal blooms(HABs)of dinoflagellates pose significant threats to aquaculture,marine ecosystems,and human health.While resting cysts have been well known for their vital roles in initiating HABs of dinoflagella...Harmful algal blooms(HABs)of dinoflagellates pose significant threats to aquaculture,marine ecosystems,and human health.While resting cysts have been well known for their vital roles in initiating HABs of dinoflagellates,mapping results of the cyst abundance and distribution in marine sediments have been also well documented to be a highly valuable predictor,and thus can be used as a basis to assess the risk of HABs.We attempted to establish a framework for the risk assessment of dinoflagellate HABs based mainly on cyst-mapping of marine sediments and a case application of it to the risk assessment of HABs in the Yellow Sea.In the framework,firstly,the targeted marine area subjected to the assessment was determined and gridded into different assessment units according to their geography,administration,and ecological or economic function.Secondly,the dinoflagellate cyst abundance from the surface sediment,HABs records,and the monitoring results of vegetative cells for all or particular species of concern were collected experimentally or by literature search,as three main indicators scored and weighted respectively with different values.The scoring and weighting process was based on scientific reasoning and empirical consideration as detailed in the text.Thirdly,the risk of HABs occurrences for all or any particular species of concern at each site was ranked with five levels according to the calculated risk values.Finally,the final evaluation results were presented with tables,matrix diagrams,and color-coded textual annotations on nautical charts.As a case application,we performed a risk assessment for HABs of target species in the Yellow Sea,which warned high risks of HABs for Karlodinium veneficum,Gymnodinium catenatum,and others.This assessment framework provides a practical and testable tool for all involved stakeholders,and subject to improvement along with the advancement of ecology of HABs.展开更多
The heritage preservation is of great intractability to the conservators as each kind of heritage material has unique and diverse requirements on temperature,humidity and air cleanliness.It is promising for metal-orga...The heritage preservation is of great intractability to the conservators as each kind of heritage material has unique and diverse requirements on temperature,humidity and air cleanliness.It is promising for metal-organic frameworks(MOFs),the multifunctional environment remediation materials,to be applied in heritage environmental protection.The advantages of MOFs lie in their multifunction like adsorption,photocatalysis,sterilization,as well as the controllable structure and properties that could be flexibly adjusted as demands,helping the heritage against various environmental threats.Thereby,the applications and the corresponding mechanisms of MOFs in cultural heritage preservation were reviewed in this work,including harmful gas adsorption,surface waterproofing,particulate matters(PM)removal,anti-bacterial and humidity control of environment.Finally,the selection principles and precautions of MOFs in heritage preservation were discussed,aiming to provide a forward-looking direction for the selection and application of MOFs.展开更多
As a frequently occurred marine pollution phenomenon,red tides of water body due to eutrophication cause massive mortality of marine organisms and serious ecological problems.The early warning and prediction of red ti...As a frequently occurred marine pollution phenomenon,red tides of water body due to eutrophication cause massive mortality of marine organisms and serious ecological problems.The early warning and prediction of red tide outbreak can provide guidance to the coastal management,and is of great value to the aquaculture industry and marine environment protection.An approach for the risk assessment of red tide occurrence using spectral indices was made.The optimal spectral indices were explored from three candidates,namely two-band ratio(TBR)method,three-band spectral index(TBSI)method,and fluorescence baseline(FLB)method.The correlations between the spectral indices and the red tide occurrence were quantitatively evaluated through analysis of variance(ANOVA).The risk maps for the Beibu Gulf and the Bohai Bay in China were produced with the normalized spectral indices based on the multi-spectral observation from Sentinel-3 satellite.Results show that both TBR and TBSI values have significant correlations with the occurrences of red tide as the ANOVA results.TBSI illustrated correctly the risk of red tide occurrence in the risk maps and was the optimal spectral index offshore risk assessment of red tide.FLB method failed to recognize the high-risk regions and may not be the appropriate spectral index.The risk assessment method proposed in this study can provide early alarms on red tide occurrence and help timely the countermeasure against potential harms.展开更多
Two-dimensional black phosphorus(2D BP)utilized in flame retardant applications frequently encounters significant challenges,including inadequate ambient stability and elevated carbon monoxide(CO)release rates.To miti...Two-dimensional black phosphorus(2D BP)utilized in flame retardant applications frequently encounters significant challenges,including inadequate ambient stability and elevated carbon monoxide(CO)release rates.To mitigate these issues,an effective approach was proposed for the fabrication of 2D heterostructures comprising copper oxide intercalated with BP in this work.This methodology takes into account both thermodynamic and kinetic factors,resulting in substantial enhancements in the ambient stability of BP and the catalytic performance for CO elimination,achieved through the synergistic interactions between 2D BP and copper oxide,all while preserving the structural integrity of 2D BP.The incorporation of gelatin and kosmotropic anions facilitated the efficient adhesion of the multifunctional heterostructures to the flammable flexible polyurethane foam(FPUF),which not only scavenged free radicals in the gas phase but also catalyzed the formation of a dense carbon layer in the condensed phase.Kosmotropic anions induce a salting-out effect that fosters the development of a chain bundle,a hydrophobic interaction domain,and a potential microphase separation region within the gelatin chains,leading to a marked improvement in the mechanical strength of the heterostructure coatings.The modified FPUF exhibited a high limiting oxygen index(LOI)value of 34%,alongside significantly improved flame resistance:the peak CO release rate was reduced by 78%,the peak heat release rate decreased by 57%,and the fire performance index(FPI)was increased by 40 times compared to untreated FPUF.The 2D heterostructure coatings demonstrated better CO catalytic removal performance relative to previously reported flame retardant products.This research offers a promising design principle for the development of next-generation high-performance flame retardant coatings aimed at enhancing fire protection.展开更多
Economic development around the Daya Bay, China has profoundly affected the marine environment in the bay area in recent years, particularly since the operation of Daya Bay Nuclear Power Station （DNPS） in 1994. This...Economic development around the Daya Bay, China has profoundly affected the marine environment in the bay area in recent years, particularly since the operation of Daya Bay Nuclear Power Station （DNPS） in 1994. This study analyzed the changes of water temperature and harmful algal blooms （HABs） for two periods： 1983-1993 and 1994-2004, using in situ and satellite data. Results showed that yearly mean surface water temperature （SWT） and Chl-a concentration （Chl-a） increased by 1.1 ℃ and 1.9 mg/m^3, respectively, after 1994. The monthly occurrence of HAB was found to have increased also. HABs appeared only in spring and autumn before 1994, but occurred all the year round after 1994. SWT, Chl-a and HABs all increased significantly in May. Those changes were associated with environmental changes in this area, such as thermal discharge from the DNPS and enhancement of eutrophication from human activities around the Daya Bay.展开更多
文摘According to the distribution of high fluoride\|bearing groundwater in Liaoning Province, China, the cause of formation and hydrogeochemical characteristics as well as its relationship with human health and illness rate were discussed. Strategies to prevent and control fluoride pollution have also been outlined.
基金Projects 50225414 supported by the National Outstanding Youth Foundation50574090, 50674087 and 50490270 by the National Natural Science Foundation of China
文摘A theory of seepage instability was used to estimate the harmfulness of water-inrush from a coal seam floor in a particular coal mine of the Mining Group,Xuzhou. Based on the stratum column chart in this coal mine,the distribu-tion of stress in mining floors when the long-wall mining was respectively pushed along to 100 m and to 150 m was simulated by using the numerical software (RFPA2D). The permeability parameters of the coal seam floor are described given the relationship between permeability parameters. Strain and the water-inrush-indices were calculated. The wa-ter-inrush-index was 67.2% when the working face was pushed to 100 m,showing that water-inrush is possible and it was 1630% when the working face was pushed to 150 m,showing that water-inrush is quite probable. The results show that as long-wall mining is pushed along,the failure zone is enlarged,the strain increased,and fissures developed cor-respondingly,resulting in the formation of water-inrush channels. Accompanied by the failure of the strata,the perme-ability increased exponentially. In contrast,the non-Darcy flow β factor and the acceleration coefficient decreased ex-ponentially,while the increase in the water-inrush-index was nearly exponential and the harmfulness of water-inrush in the coal mine increased accordingly.
文摘A new report from Jeanologia highlights theurgent need for the denim industry to adopt saferalternatives to harmful chemicals.The study alsostresses reducing excessive water use in garmentfinishing.The report,compiled in 2024,analyzed datafrom more than ll5,000 dentm finishing processes.lt found that 24%of denim finishing processes stilluse hazardous chemicals,posing risks to both theenvironment and the health of workers.
文摘This research study fabrics to ensure that they are free from carcinogenic dyes. It has been observed that there are poor-quality fabrics and consumers go to buy them without paying attention to the risks of using prohibited materials in the manufacture of these fabrics, and the use of unknown dyes has proven that some of them cause diseases to humans, especially children, that cause cancerous diseases. With the study sample consisting of (7), the study results indicate the presence of toxic formaldehyde in all sample dyes obtained from discount markets and online shopping.
基金financially supported by the Fundamental Research Funds for the Central Universities of Central South University(2023ZZTS0506).
文摘Sulfuric acid slag,a common byproduct with high iron content,poses challenges due to its high levels of harmful impurities and is often discarded as solid waste,leading to significant environmental and water pollution.To address this issue and improve resource utilization,the preparation process of oxidized pellets from sulfuric acid slag was studied,exploring suitable pelletizing systems and thermal parameters.Additionally,the removal of harmful elements and the consolidation mechanism were established during the oxidation roasting process.The findings revealed that sulfuric acid slag along with specific processing conditions,such as using two high-pressure grinding rolls and adding 1.25 wt.%bentonite,resulted in the production of qualified green pellets with desirable physical properties.Through a thermal treatment process involving preheating and roasting,the desulfurization rate of the pellets reached 95.55%and the removal efficiency of arsenic achieved 27.11%.Hematite recrystallizes,shrinks,and forms a reticulated structure with Fe2O3 recrystallization as the backbone,resulting in higher consolidation strength.
文摘Environmental pollution,which has spread across cities and villages,is doing severe harm to both nature and humans.Rivers once clear are now dirty,making fish die,while the air we breathe is filled with harmful gases that damage our health.This situation has aroused great concern among people of all ages,as no one can escape its effects.
文摘The annual average number of snowstorm days in Tongliao area is 1-3 d.Snowstorms mainly happen from October to next May,peaking from December to next March.The incidence is the highest between 12:00 and 15:00.The Mongolian low vortex is the main weather system that triggers snowstorms,and can be classified into three types:small trough development,horizontal trough becoming vertical,and low trough moving eastwards.Snowstorms pose a relatively serious threat to agricultural and animal husbandry production,transportation,power and communication in Tongliao.Especially in spring,snowstorm weather poses a greater threat to agriculture and animal husbandry in Tongliao.It is needed to pay attention to the impact of extreme weather and climate events such as snowstorms,strengthen research on the mechanisms of disaster-causing weather,enhance the early warning capability of disasters,and provide good service guarantees for low-temperature weather in winter.
基金Supported by the National Natural Science Foundation of China(Nos.32101290,52009082)the Natural Science Foundation of Jiangsu Province(No.BK20210364)the Fundamental Research Funds for the Central Universities(No.B220202044)。
文摘Suitable temperature and light intensity play important roles in the formation of harmful algae blooms(HABs),which can pose serious threats to aquatic ecosystems and human health.In this study,we measured the growth,physiological function,and paralytic shellfish toxins(PSTs)production of Alexandrium pacificum(CCMA-272),a strain isolated from East China Sea,at different temperatures(15,20,and 25℃)and light intensities(30,60,and 90μmol photons/(m^(2)·s)).Results indicate that temperature and light intensity significantly affected the growth,physiology,and toxigenic potentials of A.pacificum.The optimal conditions for the growth of A.pacificum were observed at 20℃ under60μmol photons/(m^(2)·s).Regarding the production of PSTs,this strain of A.pacificum produced 12 PSTs,including carbamate toxins:saxitoxin(STX),neosaxitoxin(NEO),and gonyautoxin 1–4(GTX1,GTX2,GTX3,GTX4);dicarbamoyl toxins:dicarbamoylsaxitoxin(dcSTX),dicarbamoylgonyautoxin 2,3(dcGTX2,dcGTX3);and N-sulfocarbamoyl toxins:N-sulfocarbamoylgonyautoxin 1,2(C1,C2),and gonyautoxin 5(GTX5).Among all the PSTs,C2 was the most abundant.Low temperature(15℃)and high light intensity(90μmol photons/(m^(2)·s))were beneficial for the production of PSTs in A.pacificum.When cultured at 20 and 25℃,A.pacificum generated comparable total quantities of PSTs,yet the toxicity levels were lower at 25℃.Intra-cellular PSTs contents were greater than extra-cellular PSTs contents,except those under the condition of 25℃ with 30μmol photons/(m^(2)·s).However,as the increase of temperature,A.pacificum released more amounts of analogues with higher toxicity levels(e.g.,STX and dcGTX_(2))into the environment than intracellularly.These findings emphasize the significant sensitivity of A.pacificum to temperature and light intensity,highlighting the importance of evaluating both intra-cellular and extra-cellular PSTs for assessing its toxicity and aiding in the prediction and management of HABs.
文摘Hypophosphatasia(HPP)is a rare metabolic bone disorder often misdiagnosed as fibromyalgia due to overlapping symptoms such as chronic pain,fatigue,and muscle weakness.This diagnostic error disproportionately affects women and can result in significant psychological distress due to repeated dismissal of symptoms.Despite low serum alkaline phosphatase(ALP)being a key biochemical clue to HPP,it is frequently overlooked in standard diagnostic evaluations.Consequen-tly,many patients endure years of ineffective treatment,invalidation,and worse-ning psychiatric outcomes.This editorial emphasizes the need for greater clinical vigilance in distinguishing HPP from fibromyalgia,particularly when features such as chronic pain,premature tooth loss,and persistently low ALP are present.Gender biases in pain diagnosis further compound this problem,leading to gr-eater misdiagnosis rates among women and contributing to the erosion of trust in medical care.The psychiatric consequences of diagnostic delays are substantial,with affected individuals experiencing elevated rates of depression,anxiety,and emotional distress.Greater recognition of low ALP as a meaningful diagnostic clue may enhance diagnostic accuracy,improve patient outcomes,and reduce the psychological toll of misdiagnosis.
基金Supported by Special Project of Performance Incentive and Guidance for Scientific Research Institutions in Chongqing(cstc2022jxjl80025).
文摘Pueraria montana is a perennial twining vine species of Pueraria in Leguminosae.Because of its fast growth and strong climbing and covering ability,this species has the potential threat of invading forest ecosystem.Based on the investigation of the occurrence and harm of P.montana in the"four mountains"forest ecosystem in the central urban area of Chongqing,combined with its growth habits and biological characteristics,we comprehensively evaluated its harm risk.The results show that P.montana is widely distributed in the forest ecosystem within the"four mountains"in the central urban area of Chongqing.On average,there was a distribution site of P.montana every 1.38 km of forest road with a scale of 0.43 hm 2/survey point and a coverage of about 42.86%.P.montana mainly occupy forest land by covering and climbing,threatening the original vegetation of forest land.It grows rapidly,and its ability of diffusion and colonization is very strong.The average length of new branches was 11.52 m/year,and the number of effective tillers was 5.25.According to National Forestry Pest Risk Analysis Index System,the risk assessment value of P.montana was 2.51,so it is a medium-risk harmful plant to forestry.It is suggested that the forestry department should strengthen the management of P.montana to prevent its further spread.
基金The National Natural Science Foundation of China under contract No.42030402the program of Shanghai Subject Chief Scientist under contract No.23XD1401200the opening foundation of the Observation and Research Station of Bohai Strait Eco-Corridor,Ministry of Natural Resources under contract No.BH202405.
文摘The blooms of Alexandrium catenella are a long-outstanding issue in the world,causing severe impacts on the local marine environment and the aquaculture industry.Our previous studies have also shown that mango peel extracts(MPE)could effectively inhibit the growth of A.catenella under controlled laboratory conditions.However,it remains unknown whether using MPE to control A.catenella-induced harmful algal blooms(HABs)in aquaculture environments will cause the release of intracellular phycotoxins into the surrounding environment,potentially affecting aquatic organisms.Additionally,the potential impact of MPE itself on aquatic life is another concern.The objective of this study was to clarify these issues primarily by assessing the ecological safety of MPE.The intracellular and extracellular paralytic shellfish toxins(PSTs)contents of A.catenella was measured throughout the experimental period using liquid chromatography tandem time-of-flight mass spectrometry(LC-TOFMS).The results showed that MPE reduced the PSTs contents in A.catenella,while no significant fluctuation was observed in the extracellular PSTs contents.Meanwhile,MPE exhibited varying degrees of inhibitory effects on the four HABs species selected in this study but promoted the growth of three of the four bait algae.The recorded results regarding the survival rate,water clearance rate,and growth rate of aquatic organism exposed to MPE showed no significant different between the control group and the experimental group.This study clarified that using MPE to govern HABs in aquaculture environments would not affect the growth of cultured organisms and demonstrated that MPE has species-specific antialgal properties.These findings contribute to a better understanding of the potential of MPE as an algaecide.
文摘Smoking increases complications and mortality in people with diabetes.Quitting delivers major benefits,but physiological(weight gain,insulin sensitivity shifts)and psychological barriers make cessation harder in this group.Our review article examined strategies tailored to people with diabetes.All smokers with diabetes should receive clear,personalized advice to quit,embedded in routine care.Among the available medications,varenicline has the strongest evidence in this population.Nicotine replacement therapy and bupropion may help but have limited diabetes-specific data,so they should be used with caution.Tobacco harm reduction(e-cigarettes,heated tobacco products)may facilitate switching away from combustible cigarettes and reduce exposure,although the long-term safety and efficacy in diabetes remain uncertain.Glucagon-like peptide-1 receptor agonists can aid weight and glycemic control and may indirectly support cessation.Digital tools(apps,wearables,and remote monitoring)offer real-time support and adherence tracking,although diabetes-specific effectiveness is still being established.Smoking cessation in people with diabetes requires urgent attention.Evidence-based interventions should be integrated into routine care,with particular attention given to early monitoring of glucose,body weight,and blood pressure after quitting,plus structured follow-up.More research should develop and test tailored,longterm strategies for this high-risk group,including pragmatic trials integrating harm reduction and digital support.
基金Supported by the National Key Research and Development Program of China(No.2022 YFC 3105201)the Science and Technology Innovation Project of Laoshan Laboratory(No.LSKJ 202203700)the Shandong Province Natural Science Foundation(No.ZR 2021 QD 025)。
文摘Harmful algal blooms(HABs)of dinoflagellates pose significant threats to aquaculture,marine ecosystems,and human health.While resting cysts have been well known for their vital roles in initiating HABs of dinoflagellates,mapping results of the cyst abundance and distribution in marine sediments have been also well documented to be a highly valuable predictor,and thus can be used as a basis to assess the risk of HABs.We attempted to establish a framework for the risk assessment of dinoflagellate HABs based mainly on cyst-mapping of marine sediments and a case application of it to the risk assessment of HABs in the Yellow Sea.In the framework,firstly,the targeted marine area subjected to the assessment was determined and gridded into different assessment units according to their geography,administration,and ecological or economic function.Secondly,the dinoflagellate cyst abundance from the surface sediment,HABs records,and the monitoring results of vegetative cells for all or particular species of concern were collected experimentally or by literature search,as three main indicators scored and weighted respectively with different values.The scoring and weighting process was based on scientific reasoning and empirical consideration as detailed in the text.Thirdly,the risk of HABs occurrences for all or any particular species of concern at each site was ranked with five levels according to the calculated risk values.Finally,the final evaluation results were presented with tables,matrix diagrams,and color-coded textual annotations on nautical charts.As a case application,we performed a risk assessment for HABs of target species in the Yellow Sea,which warned high risks of HABs for Karlodinium veneficum,Gymnodinium catenatum,and others.This assessment framework provides a practical and testable tool for all involved stakeholders,and subject to improvement along with the advancement of ecology of HABs.
基金supported by the National Natural Science Foundation of China(Nos.52308300,52370025,52108266).
文摘The heritage preservation is of great intractability to the conservators as each kind of heritage material has unique and diverse requirements on temperature,humidity and air cleanliness.It is promising for metal-organic frameworks(MOFs),the multifunctional environment remediation materials,to be applied in heritage environmental protection.The advantages of MOFs lie in their multifunction like adsorption,photocatalysis,sterilization,as well as the controllable structure and properties that could be flexibly adjusted as demands,helping the heritage against various environmental threats.Thereby,the applications and the corresponding mechanisms of MOFs in cultural heritage preservation were reviewed in this work,including harmful gas adsorption,surface waterproofing,particulate matters(PM)removal,anti-bacterial and humidity control of environment.Finally,the selection principles and precautions of MOFs in heritage preservation were discussed,aiming to provide a forward-looking direction for the selection and application of MOFs.
基金Supported by the National Key R&D Program of China(No.2023YFC3108300)the Dalian High-level Talent Innovation Program(No.2022RG02)the Fundamental Research Funds for the Central Universities(No.3132023507)。
文摘As a frequently occurred marine pollution phenomenon,red tides of water body due to eutrophication cause massive mortality of marine organisms and serious ecological problems.The early warning and prediction of red tide outbreak can provide guidance to the coastal management,and is of great value to the aquaculture industry and marine environment protection.An approach for the risk assessment of red tide occurrence using spectral indices was made.The optimal spectral indices were explored from three candidates,namely two-band ratio(TBR)method,three-band spectral index(TBSI)method,and fluorescence baseline(FLB)method.The correlations between the spectral indices and the red tide occurrence were quantitatively evaluated through analysis of variance(ANOVA).The risk maps for the Beibu Gulf and the Bohai Bay in China were produced with the normalized spectral indices based on the multi-spectral observation from Sentinel-3 satellite.Results show that both TBR and TBSI values have significant correlations with the occurrences of red tide as the ANOVA results.TBSI illustrated correctly the risk of red tide occurrence in the risk maps and was the optimal spectral index offshore risk assessment of red tide.FLB method failed to recognize the high-risk regions and may not be the appropriate spectral index.The risk assessment method proposed in this study can provide early alarms on red tide occurrence and help timely the countermeasure against potential harms.
基金supported by the National Natural Science Foundation of China(52404258)Postdoctoral Fellowship Program of CPSF(GZB20230714)+1 种基金Anhui Provincial Natural Science Foundation(2408085QE173)China Postdoctoral Science Foundation funded project(2023M743387)。
文摘Two-dimensional black phosphorus(2D BP)utilized in flame retardant applications frequently encounters significant challenges,including inadequate ambient stability and elevated carbon monoxide(CO)release rates.To mitigate these issues,an effective approach was proposed for the fabrication of 2D heterostructures comprising copper oxide intercalated with BP in this work.This methodology takes into account both thermodynamic and kinetic factors,resulting in substantial enhancements in the ambient stability of BP and the catalytic performance for CO elimination,achieved through the synergistic interactions between 2D BP and copper oxide,all while preserving the structural integrity of 2D BP.The incorporation of gelatin and kosmotropic anions facilitated the efficient adhesion of the multifunctional heterostructures to the flammable flexible polyurethane foam(FPUF),which not only scavenged free radicals in the gas phase but also catalyzed the formation of a dense carbon layer in the condensed phase.Kosmotropic anions induce a salting-out effect that fosters the development of a chain bundle,a hydrophobic interaction domain,and a potential microphase separation region within the gelatin chains,leading to a marked improvement in the mechanical strength of the heterostructure coatings.The modified FPUF exhibited a high limiting oxygen index(LOI)value of 34%,alongside significantly improved flame resistance:the peak CO release rate was reduced by 78%,the peak heat release rate decreased by 57%,and the fire performance index(FPI)was increased by 40 times compared to untreated FPUF.The 2D heterostructure coatings demonstrated better CO catalytic removal performance relative to previously reported flame retardant products.This research offers a promising design principle for the development of next-generation high-performance flame retardant coatings aimed at enhancing fire protection.
基金This study was jointly supported by the following funds awarded to Professor Danling TANG:Guangdong Natural Science Foundation(05102008 and 04001306),ChinaKey Innovation Project of Chinese Academy of Sciences(CAS)(KZCX3-SW-227-3)+3 种基金"0ne Hundred Talents Program"of CAS(Ybrjh0403)Authors are grateful to projects of South China Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences(2007TS10 and 2007ZD03)High-tech Research and Development Program of China(2006AA100303)Chinese Ecosystem Research Network(http://www.cerndata.ac.cn),Dr.Guifeng WEI of Jinan University and the Key Innovation Project of CAS(KZCX3-SW-214).
文摘Economic development around the Daya Bay, China has profoundly affected the marine environment in the bay area in recent years, particularly since the operation of Daya Bay Nuclear Power Station （DNPS） in 1994. This study analyzed the changes of water temperature and harmful algal blooms （HABs） for two periods： 1983-1993 and 1994-2004, using in situ and satellite data. Results showed that yearly mean surface water temperature （SWT） and Chl-a concentration （Chl-a） increased by 1.1 ℃ and 1.9 mg/m^3, respectively, after 1994. The monthly occurrence of HAB was found to have increased also. HABs appeared only in spring and autumn before 1994, but occurred all the year round after 1994. SWT, Chl-a and HABs all increased significantly in May. Those changes were associated with environmental changes in this area, such as thermal discharge from the DNPS and enhancement of eutrophication from human activities around the Daya Bay.
