The lime-Cu^(2+)-xanthate process is commonly used for the flotation separation of sphalerite from pyrite.In this process,lime is added to the pulp to inhibit the floatability of pyrite.However,the excessive use of li...The lime-Cu^(2+)-xanthate process is commonly used for the flotation separation of sphalerite from pyrite.In this process,lime is added to the pulp to inhibit the floatability of pyrite.However,the excessive use of lime can result in pipeline blockage and inadequate recovery of associated precious metals.Therefore,it is necessary to develop new flotation process that minimizes or eliminates the use of lime.In this paper,a novel Fe^(3+)-Cu^(2+)-butyl xanthate process was developed as an alternative to lime for separating of sphalerite from pyrite.The flotation results indicated that with the artificially-mixed minerals,the flotation recovery of pyrite was lower than 16%and that of sphalerite was higher than 47%at pH 5.0−10.0.The zeta potential measurements revealed that ferric ion preferred to adsorb on pyrite,and copper ion displaced with zinc ion from the lattice at the interface of sphalerite.The wettability analyses indicated that the hydrophobicity of sphalerite surface increased apparently after being treated with Fe^(3+)-Cu^(2+)-BX,while the hydrophobicity of pyrite surface remained nearly unchanged.With XPS analysis,Cu-S bond and hydrophilic ferric hydroxide were detected separately on the surface of sphalerite and pyrite after conditioning with Fe^(3+)-Cu^(2+)-BX,which facilitated the flotation separation of sphalerite from pyrite with butyl xanthate collector.展开更多
A zinc sulfate open framework matrix,[Zn(SO_4)(DMSO)](1),was synthesized by solvothermal evaporationusing dimethyl sulfoxide(DMSO)as the solvent.A compositeP@1,which exhibits fluorescence and room tempera-ture phospho...A zinc sulfate open framework matrix,[Zn(SO_4)(DMSO)](1),was synthesized by solvothermal evaporationusing dimethyl sulfoxide(DMSO)as the solvent.A compositeP@1,which exhibits fluorescence and room tempera-ture phosphorescence(RTP)properties,was prepared by doping 2,6-naphthalic acid(P)into matrix1at a low con-centration.P@1emitted a green RTP that was visible to the naked eye and lasted for approximately 2 s.P@1exhib-ited selective phosphorescence enhancement response towards Pb^(2+),with a detection limit of 2.52μmol·L^(-1).Themain detection mechanism is the Pb—O coordination-induced phosphorescence enhancement in the system.Inter-estingly,P@1also functioned as a dual-channel probe for the rapid detection of Fe^(3+)ions through fluorescencequenching with a detection limit of 0.038μmol·L^(-1).The recognition mechanism may be attributed to the competi-tive energy absorption betweenP@1and Fe^(3+)ions.CCDC:2388502,1.展开更多
Electrochromic(EC)smart windows utilizing a reversible metal electrodeposition device(RMED)offer a compelling alternative for dynamically regulating transmissions of optical and thermal energy.An EC device(ECD)is cons...Electrochromic(EC)smart windows utilizing a reversible metal electrodeposition device(RMED)offer a compelling alternative for dynamically regulating transmissions of optical and thermal energy.An EC device(ECD)is constructed by reversible metal electrodeposition(RME)of Bi/Cu on WO_(3)·xH_(2)O film electrodeposited onto fluorine-doped tin oxide(FTO)transparent conductive glass.The electrolyte consists of CuCl_(2),BiCl_(3),KCl and HCl aqueous solution,supplying necessary components for both electrochemical and electrodeposition processes.The ECD shows ability to rapidly transition between colorless and black states,which achieves a large optical modulation of 77.0%at 570 nm.In the black state,the ECD exhibits a near-zero transmittance in the wavelength range of 400-1100 nm while maintaining 96.6%of its initial optical modulation after coloration/bleaching cycling of 60000 s,exhibiting good cyclic stability.This RMED has relatively high stability under open-circuit voltage and also possesses excellent heat insulation performance.The results offer a solution to overcome the poor cyclic stability of RMEDs and improve the optical modulation of ECDs.展开更多
Pathological cardiac hypertrophy is an early and significant cardiac structural characteristic that contributes to the onset and progression of heart failure(HF).Its mainly structural feature is the abnormally enlarge...Pathological cardiac hypertrophy is an early and significant cardiac structural characteristic that contributes to the onset and progression of heart failure(HF).Its mainly structural feature is the abnormally enlarged cardiomyocyte.Effective intervention targets for abnormally enlarged cardiomyocyte remain to be identified.Previous studies have shown that the cellular shape and size can be regulated by the actin related protein 2/3(Arp2/3)complex,which is an actin-binding protein complex involved in the actin nucleation and assembly.However,the roles of the Arp2/3 complex in cardiomyocyte hypertrophy remain unknown.Here our study identifies its novel roles in the occurrence and development of cardiomyocyte hypertrophy.We found that mRNA levels of all subunits from the Arp2/3 complex are significantly upregulated(P<0.05)in the angiotensin Ⅱ(Ang Ⅱ)-induced neonatal rat primary and H9c2 cardiomyocyte hypertrophy.Further studies showed that siRNA-directed ARPC 2 silencing inhibits the reactivation of fetal genes and enlargement of cardiomyocyte area induced by Ang Ⅱ in neonatal rat primary cardiomyocytes(NRCMs)and H9c2 cells(P<0.05).In addition,the upstream activators of the Arp2/3 complex including SH3 protein interacting with Nck,90 kD(SPIN90)and Ras-related C3 botulinum toxin substrate 1(Rac1)/WASp family Verprolin-homologous protein-2(WAVE-2)are upregulated(P<0.05)in Ang Ⅱ-induced neonatal rat primary and H9c2 cardiomyocyte hypertrophy,indicating the excessive activation of the Arp2/3 complex.We further show that CK666,a specific Arp2/3 complex inhibitor,prevents the reactivation of fetal genes and the enlargement of cardiomyocyte area induced by Ang Ⅱ in NRCMs and H9c2 cells(P<0.05).Our results reveal that the Arp2/3 complex plays a crucial role in Ang Ⅱ-induced cardiomyocyte hypertrophy,which is beneficial to further studies about the molecular mechanisms by which the Arp2/3 complex regulates pathological cardiac hypertrophy.展开更多
基金Project(52204363)supported by the National Natural Science Foundation of ChinaProject(2024JJ8042)supported by the Hunan Natural Science Foundation,ChinaProject(22C0220)supported by the Education Department of Hunan Province,China。
文摘The lime-Cu^(2+)-xanthate process is commonly used for the flotation separation of sphalerite from pyrite.In this process,lime is added to the pulp to inhibit the floatability of pyrite.However,the excessive use of lime can result in pipeline blockage and inadequate recovery of associated precious metals.Therefore,it is necessary to develop new flotation process that minimizes or eliminates the use of lime.In this paper,a novel Fe^(3+)-Cu^(2+)-butyl xanthate process was developed as an alternative to lime for separating of sphalerite from pyrite.The flotation results indicated that with the artificially-mixed minerals,the flotation recovery of pyrite was lower than 16%and that of sphalerite was higher than 47%at pH 5.0−10.0.The zeta potential measurements revealed that ferric ion preferred to adsorb on pyrite,and copper ion displaced with zinc ion from the lattice at the interface of sphalerite.The wettability analyses indicated that the hydrophobicity of sphalerite surface increased apparently after being treated with Fe^(3+)-Cu^(2+)-BX,while the hydrophobicity of pyrite surface remained nearly unchanged.With XPS analysis,Cu-S bond and hydrophilic ferric hydroxide were detected separately on the surface of sphalerite and pyrite after conditioning with Fe^(3+)-Cu^(2+)-BX,which facilitated the flotation separation of sphalerite from pyrite with butyl xanthate collector.
文摘A zinc sulfate open framework matrix,[Zn(SO_4)(DMSO)](1),was synthesized by solvothermal evaporationusing dimethyl sulfoxide(DMSO)as the solvent.A compositeP@1,which exhibits fluorescence and room tempera-ture phosphorescence(RTP)properties,was prepared by doping 2,6-naphthalic acid(P)into matrix1at a low con-centration.P@1emitted a green RTP that was visible to the naked eye and lasted for approximately 2 s.P@1exhib-ited selective phosphorescence enhancement response towards Pb^(2+),with a detection limit of 2.52μmol·L^(-1).Themain detection mechanism is the Pb—O coordination-induced phosphorescence enhancement in the system.Inter-estingly,P@1also functioned as a dual-channel probe for the rapid detection of Fe^(3+)ions through fluorescencequenching with a detection limit of 0.038μmol·L^(-1).The recognition mechanism may be attributed to the competi-tive energy absorption betweenP@1and Fe^(3+)ions.CCDC:2388502,1.
文摘Electrochromic(EC)smart windows utilizing a reversible metal electrodeposition device(RMED)offer a compelling alternative for dynamically regulating transmissions of optical and thermal energy.An EC device(ECD)is constructed by reversible metal electrodeposition(RME)of Bi/Cu on WO_(3)·xH_(2)O film electrodeposited onto fluorine-doped tin oxide(FTO)transparent conductive glass.The electrolyte consists of CuCl_(2),BiCl_(3),KCl and HCl aqueous solution,supplying necessary components for both electrochemical and electrodeposition processes.The ECD shows ability to rapidly transition between colorless and black states,which achieves a large optical modulation of 77.0%at 570 nm.In the black state,the ECD exhibits a near-zero transmittance in the wavelength range of 400-1100 nm while maintaining 96.6%of its initial optical modulation after coloration/bleaching cycling of 60000 s,exhibiting good cyclic stability.This RMED has relatively high stability under open-circuit voltage and also possesses excellent heat insulation performance.The results offer a solution to overcome the poor cyclic stability of RMEDs and improve the optical modulation of ECDs.
文摘Pathological cardiac hypertrophy is an early and significant cardiac structural characteristic that contributes to the onset and progression of heart failure(HF).Its mainly structural feature is the abnormally enlarged cardiomyocyte.Effective intervention targets for abnormally enlarged cardiomyocyte remain to be identified.Previous studies have shown that the cellular shape and size can be regulated by the actin related protein 2/3(Arp2/3)complex,which is an actin-binding protein complex involved in the actin nucleation and assembly.However,the roles of the Arp2/3 complex in cardiomyocyte hypertrophy remain unknown.Here our study identifies its novel roles in the occurrence and development of cardiomyocyte hypertrophy.We found that mRNA levels of all subunits from the Arp2/3 complex are significantly upregulated(P<0.05)in the angiotensin Ⅱ(Ang Ⅱ)-induced neonatal rat primary and H9c2 cardiomyocyte hypertrophy.Further studies showed that siRNA-directed ARPC 2 silencing inhibits the reactivation of fetal genes and enlargement of cardiomyocyte area induced by Ang Ⅱ in neonatal rat primary cardiomyocytes(NRCMs)and H9c2 cells(P<0.05).In addition,the upstream activators of the Arp2/3 complex including SH3 protein interacting with Nck,90 kD(SPIN90)and Ras-related C3 botulinum toxin substrate 1(Rac1)/WASp family Verprolin-homologous protein-2(WAVE-2)are upregulated(P<0.05)in Ang Ⅱ-induced neonatal rat primary and H9c2 cardiomyocyte hypertrophy,indicating the excessive activation of the Arp2/3 complex.We further show that CK666,a specific Arp2/3 complex inhibitor,prevents the reactivation of fetal genes and the enlargement of cardiomyocyte area induced by Ang Ⅱ in NRCMs and H9c2 cells(P<0.05).Our results reveal that the Arp2/3 complex plays a crucial role in Ang Ⅱ-induced cardiomyocyte hypertrophy,which is beneficial to further studies about the molecular mechanisms by which the Arp2/3 complex regulates pathological cardiac hypertrophy.
