Modification of nickel sulfide cocatalysts is considered to be a promising approach for efficient enhancement of the photocatalytic hydrogen production performance of g-C3N4.Providing more NiS cocatalyst to function a...Modification of nickel sulfide cocatalysts is considered to be a promising approach for efficient enhancement of the photocatalytic hydrogen production performance of g-C3N4.Providing more NiS cocatalyst to function as active sites of g-C3N4 is still highly desirable.To realize this goal,in this work,a facile sulfur-mediated photodeposition approach was developed.Specifically,photogenerated electrons excited by visible light reduce the S molecules absorbed on g-C3N4 surface to S^2‒,and subsequently NiS cocatalyst is formed in situ on the g-C3N4 surface by a combination of Ni2+and S2‒due to their small solubility product constant(Ksp=3.2×10^‒19).This approach has several advantages.The NiS cocatalyst is clearly in situ deposited on the photogenerated electron transfer sites of g-C3N4,and thus provides more active sites for H2 production.In addition,this method utilizes solar energy with mild reaction conditions at room temperature.Consequently,the synthesized NiS/g-C3N4 photocatalyst achieves excellent hydrogen generation performance with the performance of the optimal sample(244μmol h^‒1 g^‒1)close to that of 1 wt%Pt/g-C3N4(316μmol h^‒1 g^‒1,a well-known excellent photocatalyst).More importantly,the present sulfur-mediated photodeposition route is versatile and facile and can be used to deposit various metal sulfides such as CoSx,CuSx and AgSx on the g-C3N4 surface,and all the resulting metal sulfide-modified g-C3N4 photocatalysts exhibit improved H2-production performance.Our study offers a novel insight for the synthesis of high-efficiency photocatalysts.展开更多
针对含光伏(photovoltaic,PV)、电动汽车(electric vehicle,EV)及家庭电器负荷的智能社区,以车入户(vehicle to home,V2H)的形式将EV纳入家庭需求响应框架,利用EV的双向输能特性并考虑EV充/放电带来的电池容量退化成本,协同PV、电网的...针对含光伏(photovoltaic,PV)、电动汽车(electric vehicle,EV)及家庭电器负荷的智能社区,以车入户(vehicle to home,V2H)的形式将EV纳入家庭需求响应框架,利用EV的双向输能特性并考虑EV充/放电带来的电池容量退化成本,协同PV、电网的实时电价和用户需求的可容忍时延,基于Lyapunov优化理论提出随机环境下V2H用户的EV充/放电调度策略和每户家庭的负荷响应策略,最小化家庭用户的长期平均购电成本。并提出一种智能社区在线能量交易方案,旨在最小化智能社区总的购电成本、最大限度提高社区能源利用率。理论分析和仿真结果表明,所提算法无需实时电价、PV出力、用户负荷需求的先验概率信息,仅基于当前系统状态就可使优化目标趋于最优值,实现家庭用户的能量调度和家庭用户之间的能量共享,减少家庭购电成本,提高用户之间能量交易的灵活性。展开更多
为了探讨了H2H(Hospital To Home)营养管理模式下的持续营养补充对食管癌患者术后营养状况及生活质量的影响,选取了在胸外科首次确诊为食管癌并接受手术治疗的81例患者为研究对象,随机分为实验组和对照组。对照组实行常规营养管理,实验...为了探讨了H2H(Hospital To Home)营养管理模式下的持续营养补充对食管癌患者术后营养状况及生活质量的影响,选取了在胸外科首次确诊为食管癌并接受手术治疗的81例患者为研究对象,随机分为实验组和对照组。对照组实行常规营养管理,实验组采取H2H营养管理模式进行持续营养补充。结果显示,两组患者术后血红蛋白浓度均有不同程度下降,且实验组术后3 d的血红蛋白浓度低于对照组(P=0.037)。术后3 d的血清白蛋白(38.2 g·L^(-1))及前白蛋白(256.7 g·L^(-1))浓度实验组均高于对照组(36.3、180.9 g·L^(-1),均有P<0.05)。两组患者术后总蛋白和前白蛋白浓度均有下降,出院后逐渐回升,实验组的总体趋势高于对照组。对生活质量进行评估,实验组术后6个月的躯体功能、情绪功能及总体健康水平得分均显著高于对照组(81.7 vs 70.2,85.5 vs 75.0,73.0 vs 62.8,均有P<0.05)。综上,H2H营养管理模式下的持续营养补充可改善食管癌患者术后营养状况,提高生活质量,有助于改善预后。H2H营养管理模式可为肿瘤患者术后长期营养管理提供参考模式。展开更多
为确定H9N2猪流感病毒(H9N2-SIV)通过瞬时受体电位通道M2(TRPM2)介导肺微血管上皮细胞(PMVEC)铁死亡的分子机制,使用H9N2-SIV接种PMVEC,构建TRPM2-siRNA质粒并转染细胞。用透射电镜观察细胞超微结构,用荧光探针法检测活性氧(ROS)、Ca^(...为确定H9N2猪流感病毒(H9N2-SIV)通过瞬时受体电位通道M2(TRPM2)介导肺微血管上皮细胞(PMVEC)铁死亡的分子机制,使用H9N2-SIV接种PMVEC,构建TRPM2-siRNA质粒并转染细胞。用透射电镜观察细胞超微结构,用荧光探针法检测活性氧(ROS)、Ca^(2+)和Fe^(2+);用生化试剂盒检测丙二醛(MDA)和谷胱甘肽(GSH)含量,并通过荧光定量PCR和Western-blot检测葡萄糖调节蛋白78(GRP78)、TRPM2、蛋白激酶R样内质网激酶(PERK)、活化转录因子4(ATF4)、阳离子转运调控样蛋白1(CHAC1)、谷胱甘肽过氧化物酶4(GPX4)的m RNA和蛋白表达水平。结果显示,H9N2-SIV感染可诱导细胞铁死亡,敲低TRPM2可以减少细胞内ROS水平,降低Ca^(2+)、Fe^(2+)及MDA含量,GSH水平明显增加;此外,GRP78、PERK、ATF4、CHAC1 m RNA和蛋白表达水平下调,GPX4的m RNA和蛋白表达水平上调。结果表明,H9N2-SIV感染可诱导细胞铁死亡,其可通过激活TRPM2使Ca^(2+)内流增多,进而激活PERK/ATF4/CHAC1信号通路,加速GSH耗竭,抑制GPX4的活性,促进细胞铁死亡。展开更多
文摘Modification of nickel sulfide cocatalysts is considered to be a promising approach for efficient enhancement of the photocatalytic hydrogen production performance of g-C3N4.Providing more NiS cocatalyst to function as active sites of g-C3N4 is still highly desirable.To realize this goal,in this work,a facile sulfur-mediated photodeposition approach was developed.Specifically,photogenerated electrons excited by visible light reduce the S molecules absorbed on g-C3N4 surface to S^2‒,and subsequently NiS cocatalyst is formed in situ on the g-C3N4 surface by a combination of Ni2+and S2‒due to their small solubility product constant(Ksp=3.2×10^‒19).This approach has several advantages.The NiS cocatalyst is clearly in situ deposited on the photogenerated electron transfer sites of g-C3N4,and thus provides more active sites for H2 production.In addition,this method utilizes solar energy with mild reaction conditions at room temperature.Consequently,the synthesized NiS/g-C3N4 photocatalyst achieves excellent hydrogen generation performance with the performance of the optimal sample(244μmol h^‒1 g^‒1)close to that of 1 wt%Pt/g-C3N4(316μmol h^‒1 g^‒1,a well-known excellent photocatalyst).More importantly,the present sulfur-mediated photodeposition route is versatile and facile and can be used to deposit various metal sulfides such as CoSx,CuSx and AgSx on the g-C3N4 surface,and all the resulting metal sulfide-modified g-C3N4 photocatalysts exhibit improved H2-production performance.Our study offers a novel insight for the synthesis of high-efficiency photocatalysts.
文摘针对含光伏(photovoltaic,PV)、电动汽车(electric vehicle,EV)及家庭电器负荷的智能社区,以车入户(vehicle to home,V2H)的形式将EV纳入家庭需求响应框架,利用EV的双向输能特性并考虑EV充/放电带来的电池容量退化成本,协同PV、电网的实时电价和用户需求的可容忍时延,基于Lyapunov优化理论提出随机环境下V2H用户的EV充/放电调度策略和每户家庭的负荷响应策略,最小化家庭用户的长期平均购电成本。并提出一种智能社区在线能量交易方案,旨在最小化智能社区总的购电成本、最大限度提高社区能源利用率。理论分析和仿真结果表明,所提算法无需实时电价、PV出力、用户负荷需求的先验概率信息,仅基于当前系统状态就可使优化目标趋于最优值,实现家庭用户的能量调度和家庭用户之间的能量共享,减少家庭购电成本,提高用户之间能量交易的灵活性。
文摘为了探讨了H2H(Hospital To Home)营养管理模式下的持续营养补充对食管癌患者术后营养状况及生活质量的影响,选取了在胸外科首次确诊为食管癌并接受手术治疗的81例患者为研究对象,随机分为实验组和对照组。对照组实行常规营养管理,实验组采取H2H营养管理模式进行持续营养补充。结果显示,两组患者术后血红蛋白浓度均有不同程度下降,且实验组术后3 d的血红蛋白浓度低于对照组(P=0.037)。术后3 d的血清白蛋白(38.2 g·L^(-1))及前白蛋白(256.7 g·L^(-1))浓度实验组均高于对照组(36.3、180.9 g·L^(-1),均有P<0.05)。两组患者术后总蛋白和前白蛋白浓度均有下降,出院后逐渐回升,实验组的总体趋势高于对照组。对生活质量进行评估,实验组术后6个月的躯体功能、情绪功能及总体健康水平得分均显著高于对照组(81.7 vs 70.2,85.5 vs 75.0,73.0 vs 62.8,均有P<0.05)。综上,H2H营养管理模式下的持续营养补充可改善食管癌患者术后营养状况,提高生活质量,有助于改善预后。H2H营养管理模式可为肿瘤患者术后长期营养管理提供参考模式。
文摘为确定H9N2猪流感病毒(H9N2-SIV)通过瞬时受体电位通道M2(TRPM2)介导肺微血管上皮细胞(PMVEC)铁死亡的分子机制,使用H9N2-SIV接种PMVEC,构建TRPM2-siRNA质粒并转染细胞。用透射电镜观察细胞超微结构,用荧光探针法检测活性氧(ROS)、Ca^(2+)和Fe^(2+);用生化试剂盒检测丙二醛(MDA)和谷胱甘肽(GSH)含量,并通过荧光定量PCR和Western-blot检测葡萄糖调节蛋白78(GRP78)、TRPM2、蛋白激酶R样内质网激酶(PERK)、活化转录因子4(ATF4)、阳离子转运调控样蛋白1(CHAC1)、谷胱甘肽过氧化物酶4(GPX4)的m RNA和蛋白表达水平。结果显示,H9N2-SIV感染可诱导细胞铁死亡,敲低TRPM2可以减少细胞内ROS水平,降低Ca^(2+)、Fe^(2+)及MDA含量,GSH水平明显增加;此外,GRP78、PERK、ATF4、CHAC1 m RNA和蛋白表达水平下调,GPX4的m RNA和蛋白表达水平上调。结果表明,H9N2-SIV感染可诱导细胞铁死亡,其可通过激活TRPM2使Ca^(2+)内流增多,进而激活PERK/ATF4/CHAC1信号通路,加速GSH耗竭,抑制GPX4的活性,促进细胞铁死亡。
