Objective To develop an onset risk prediction nomogram for patients with homocysteine-type(H-type)hypertension(HTH)based on pulse diagram parameters to assist early clinical prediction and diagnosis of HTH.Methods Pat...Objective To develop an onset risk prediction nomogram for patients with homocysteine-type(H-type)hypertension(HTH)based on pulse diagram parameters to assist early clinical prediction and diagnosis of HTH.Methods Patients diagnosed with essential hypertension and admitted to Shanghai Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shang-hai Hospital of Traditional Chinese Medicine,and Shanghai Hospital of Integrated Tradition-al Chinese and Western Medicine from July 6th 2020 to June 16th 2021,and from August 11th 2023 to January 22nd 2024,were enrolled in this retrospective research.The baselines and clinical biochemical indicators of patients were collected.The SMART-I TCM pulse instru-ment was applied to gather pulse diagram parameters.Multivariate logistic regression was adopted to analyze the risk factors for HTH.RStudio was employed to construct the nomo-gram model,receiver operating characteristic(ROC)curve,and calibration curve(bootstrap self-sampling 200 times),and clinical decision curve were drawn to evaluate the model’s dis-crimination and clinical effectiveness.Results A total of 168 hospitalized patients with essential hypertension were selected and di-vided into non-HTH group(n=29)and HTH group(n=139).Compared with non-HTH group,HTH group had a lower body mass index(BMI),and higher proportions of male pa-tients and drinkers(P<0.05).The ventricular wall thickening(VWT)could not be deter-mined.The proportions of left common carotid intima-media wall thickness(LCCIMWT)and serum creatinine(SCR)were higher in HTH group(P<0.05).The pulse diagram parameter As was significantly higher,and H4/H1 and T1/T were lower in HTH group(P<0.05).Gender,al-cohol consumption,serum creatinine,and the pulse diagram parameter H4/H1 were identi-fied as independent risk factors for HTH(P<0.05).The nomogram’s area under the ROC curve(AUC)was 0.795[95%confidence interval(CI):(0.7066,0.8828)],with a specificity of 0.724 and sensitivity of 0.799.After 200 times repeated bootstrap self-samplings,the calibra-tion curve showed that the simulated curve fits well with the actual curve(x^(2)=9.5002,P=0.3019).The clinical decision curve indicated that the nomogram’s applicability was optimal when the threshold for predicting HTH was between 0.38 and 1.00.Conclusion The nomogram model could be valuable for predicting the onset risk of HTH and pulse diagram parameters can facilitate early screening and prevention of HTH.展开更多
The bent double-ridged rectangular tube(DRRT)with high forming quality is helpful to improve the microwave transmission accuracy.For reducing the cross-sectional deformation in the H-typed bending process,in addition ...The bent double-ridged rectangular tube(DRRT)with high forming quality is helpful to improve the microwave transmission accuracy.For reducing the cross-sectional deformation in the H-typed bending process,in addition to using rigid mandrel to support the inside of tube,ridge groove fillers are also added to restrict the deformation of ridge grooves.Because of the change of stress and strain state of bent tube in bending,rigid mandrel retracting and specially twicespringback stages,and the springback of fillers,the cross-sectional deformation of tube in each stage may be different.Therefore,based on the ABAQUS platform,the finite element models(FEM)for H-typed bending,mandrel retracting and twice-springback stages of H96 DRRT with fillers were established and validated.It is found that,for the height and width deformation of tube and spacing deformation of ridge grooves,retraction of mandrel can make the distribution of these deformations more uniform along the bending direction.The first springback can reduce these deformations significantly,which should be emphasized.But the second springback only increases them by less amount,which can be ignored.The smaller height deformation of ridge groove and filler can be neglected.展开更多
Let △ be full Laplacian on H-type group G. Then for every compact set D Ga local estimate of the Schrodinger maximal operator holds, that is,∫D^sup0〈t〈1｜e^it△f（x）｜^2dx≤｜｜f｜｜^2H^s,s〉1/2We also show that ...Let △ be full Laplacian on H-type group G. Then for every compact set D Ga local estimate of the Schrodinger maximal operator holds, that is,∫D^sup0〈t〈1｜e^it△f（x）｜^2dx≤｜｜f｜｜^2H^s,s〉1/2We also show that the above inequality fails when s 〈 1/4.展开更多
H-type amphiphilic liquid crystalline block copolymers containing azobenzene were synthesized by atom transfer radical polymerization （ATRP）. Macroinitiators prepared by the esterification between poly（ethylene ox...H-type amphiphilic liquid crystalline block copolymers containing azobenzene were synthesized by atom transfer radical polymerization （ATRP）. Macroinitiators prepared by the esterification between poly（ethylene oxide） （PEG） and 2,2-dichloroacetyl chloride were utilized to initiate the polymerization of 6-[4-（4-ethoxyphenylazo）phenoxy]hexyl rnethacrylate （M6C）. The resulting macroinitiators and block copolymers were characterized by ^1H NMR, gel permeation chromatography （GPC）. Polarizing optical microscopy （POM） and differential scanning calorimetry （DSC） preliminarily revealed the liquid crystalline property of these block copolymers. This series of liquid crystalline block copolymers are promising in some areas, such as optical data storage, optical switch, and molecular devices.展开更多
Due to the loose structure,high porosity and high permeability of soil-rock mixture slope,the slope is unstable and may cause huge economic losses and casualties.The h-type anti-slide pile is regarded as an effective ...Due to the loose structure,high porosity and high permeability of soil-rock mixture slope,the slope is unstable and may cause huge economic losses and casualties.The h-type anti-slide pile is regarded as an effective means to prevent the instability of soilrock mixture slope.In this paper,a centrifuge model test was conducted to investigate the stress distribution of the h-type anti-slide pile and the evolution process of soil arching during the loading.A numerical simulation model was built based on the similar relationship between the centrifuge model and the prototype to investigate the influence factors of the pile spacing,anchored depth,and crossbeam stiffness,and some recommendations were proposed for its application.The results show that the bending moment distribution of the rear pile exhibits Wshaped,while for the front pile,its distribution resembles V-shaped.The soil arching evolution process during loading is gradually dissipated from bottom to top and from far to near.During the loading,the change of bending moment can be divided into three stages,namely,the stabilization stage,the slow growth stage,and the rapid growth stage.In engineering projects,the recommended values of the pile spacing,anchored depth,and crossbeam stiffness are 4.0d,2.0d,and 2.0EI,where d and EI are the diameter and bending stiffness of the h-type anti-slide pile respectively.展开更多
H-type zeolites（ HY, Hβ, and HM） were synthesized and characterized by XRD, NH3-TPD, and Py-IR. Selectively catalytic alkylation of naphthalene with n-hexanol to hexyl-naphthalene over the zeolites was carried out....H-type zeolites（ HY, Hβ, and HM） were synthesized and characterized by XRD, NH3-TPD, and Py-IR. Selectively catalytic alkylation of naphthalene with n-hexanol to hexyl-naphthalene over the zeolites was carried out. The experimental results show that the catalytic activities of the zeolites are mainly determined by their acid properties and pore structures. The larger the pore diameter is, the higher the catalytic activity is. NH3-TPD profiles show that Hβ and HM have lower acid strengths than HY. HY has both the highest activity and highest selectivity for the hexylnaphthalene. Higher reaction temperatures and longer reaction time are beneficial to the production of β-hexyl-naphthalene over the HY zeolite.展开更多
Objective:To study the relationship between serum inflammatory response cytokines and the change of plaque properties in patients with H-type hypertension complicated by carotid atherosclerosis.Methods: Patients who w...Objective:To study the relationship between serum inflammatory response cytokines and the change of plaque properties in patients with H-type hypertension complicated by carotid atherosclerosis.Methods: Patients who were diagnosed with H-type hypertension complicated by carotid atherosclerosis in Yulin Hospital of Traditional Chinese Medicine between May 2014 and December 2016 were selected as group A, patients with H-type hypertension complicated by carotid atherosclerosis and normal Hcy levels were selected as group B, patients with carotid atherosclerosis and normal blood pressure levels and Hcy levels were selected as group C, and healthy volunteers during the same period were selected as control group. Serum levels of inflammatory response cytokines and plaque property-related cytokines were detected.Results: Serum Hcy, sICAM-1, MCP-1, YKL-40, IL-6, PTX3, FGF23, MMP9 and Caspase-3 levels of group A, group B and group C were significantly higher than those of group D, serum Hcy, sICAM-1, MCP-1, YKL-40, IL-6, PTX3, FGF23, MMP9 and Caspase-3 levels of group A and group B were significantly higher than those of group C, and serum Hcy, sICAM-1, MCP-1, YKL-40, IL-6, PTX3, FGF23, MMP9 and Caspase-3 levels of group A were significantly higher than those of group B;serum Hcy, sICAM-1, MCP-1, YKL-40, IL-6, PTX3, FGF23, MMP9 and Caspase-3 levels of group A with vulnerable plaques were significantly higher than those of patients with stable plaques. Serum Hcy, sICAM-1, MCP-1, YKL-40 and IL-6 levels of group A were positively correlated with PTX3, FGF23, MMP9 and Caspase-3 levels.Conclusion: Serum inflammatory response cytokine secretion increases in patients with H-type hypertension complicated by carotid atherosclerosis, and it can result in the change in plaque properties and the decrease in stability.展开更多
Purpose: To show for which publication-citation arrays h-type indices are equal and to reconsider rational h-type indices. Results for these research questions fill some gaps in existing basic knowledge about h-type i...Purpose: To show for which publication-citation arrays h-type indices are equal and to reconsider rational h-type indices. Results for these research questions fill some gaps in existing basic knowledge about h-type indices.Design/methodology/approach: The results and introduction of new indicators are based on well-known definitions.Findings: The research purpose has been reached: answers to the first questions are obtained and new indicators are defined. Research limitations: h-type indices do not meet the Bouyssou-Marchant independence requirement.Practical implications: On the one hand, more insight has been obtained for well-known indices such as the h-and the g-index and on the other hand, simple extensions of existing indicators have been added to the bibliometric toolbox. Relative rational h-type indices are more useful for individuals than the existing absolute ones.Originality/value: Answers to basic questions such as "when are the values of two h-type indices equal" are provided. A new rational h-index is introduced.展开更多
This article obtains an explicit expression of the heat kernels on H-type groups and then follow the estimate of heat kernels to deduce the Hardy＇s uncertainty principle on the nilpotent Lie groups.
Numerical simulations are conducted to improve the energy acquisition efficiency of H-type vertical axis wind turbines through the optimization of the related blade airfoil aerodynamic performance.The Bézier curve...Numerical simulations are conducted to improve the energy acquisition efficiency of H-type vertical axis wind turbines through the optimization of the related blade airfoil aerodynamic performance.The Bézier curve is initi-ally used tofit the curve profile of a NACA2412 airfoil,and the moving asymptote algorithm is then exploited to optimize the design of the considered H-type vertical-axis wind-turbine blade airfoil for a certain attack angle.The results show that the maximum lift coefficient of the optimized airfoil is 8.33%higher than that of the original airfoil.The maximum lift-to-drag ratio of the optimized airfoil exceeds the maximum lift-to-drag ratio of the ori-ginal airfoil by 11.22%.Moreover,the power coefficient is increased by 12.19%and the torque coefficient of the wind turbine is significantly improved.展开更多
Structural, electronic and mechanical properties of the nH-SiC （n = 2, 4, 6, 8 and 10） polytypes are calculated by using the first-principles calculations based on the density-functional theory approach. The optimiz...Structural, electronic and mechanical properties of the nH-SiC （n = 2, 4, 6, 8 and 10） polytypes are calculated by using the first-principles calculations based on the density-functional theory approach. The optimized lattice parameters of nH-SiC are in good agreement with the experimental data. The mechanical properties, including elastic constants, bulk modulus, Young＇s modulus, shear modulus and Poisson＇s ratio, are calculated. The analysis of elastic properties indicates that the effects of n on the mechanical properties of the five nil-SiC structures have no difference. The indirect band gap relationship for the live polytypes is Ebg2H 〉 Ebg4H 〉 Ebg6H 〉 Ebg10H 〉 EbgsH.展开更多
Objective:To explore the correlation of carotid intima media thickness with function in patients with H-type hypertension and acute cerebral infarction.Methods:A total of 150 patients with acute cerebral infarction wh...Objective:To explore the correlation of carotid intima media thickness with function in patients with H-type hypertension and acute cerebral infarction.Methods:A total of 150 patients with acute cerebral infarction who were admitted in our hospital from June, 2016 to June, 2017 were included in the study and divided into H-type hypertension group (H-type hypertension merged with acute cerebral infarction, Hcy≥10 μmol/L), non-H-type hypertension group (non- H-type hypertension merged with acute cerebral infarction, Hcy≥10 μmol/L), and the control group (no hypertension but with acute cerebral infarction) according to Hcy level and whether being suffered from hypertension or not with 50 cases in each group. Moreover, 50 healthy individuals who came for physical examinations were served as the healthy group. The morning fasting peripheral venous blood was collected at physical examination time for patients in the healthy group and after admission for patients with acute cerebral infarction. Hcy, sICAM-1, MCP-1, and YKL-40 were detected. The color Doppler ultrasound diagnostic apparatus was used to detect IMT, distensibility, and stiffness. Results: Hcy, MCP-1, sICAM-1, and YKL-40 levels in H-type hypertension group, non-H-type hypertension group, and the control group were significantly higher than those in the healthy group. Hcy, MCP-1, sICAM-1, and YKL-40 levels in H-type hypertension group and non-H-type hypertension group were significantly higher than those in the control group. Hcy, MCP-1, sICAM-1, and YKL-40 levels in H-type hypertension group were significantly higher than those in non-H-type hypertension group. IMT and stiffness in H-type hypertension group, non-H-type hypertension group, and the control group were significantly greater than those in the healthy group, while distensibility was significantly less than that in the healthy group. IMT and stiffness in H-type hypertension group and non-H-type hypertension group were significantly greater than those in the control group, while distensibility was significantly less than that in the control group. IMT and stiffness in H-type hypertension group were significantly greater than those in non-H-type hypertension group, while distensibility was significantly less than that in non-H-type hypertension group.Conclusions: Hcy can directly affect carotid AS, increase carotid IMT, and promote the occurrence of hypertension merged with acute cerebral infarction;therefore, positive monitoring of serum Hcy level and IMT thickness in patients with hypertension and acute cerebral infarction and early intervention are of great significance in reducing the occurrence of carotid AS, delaying the progression of carotid AS, and preventing hypertension and acute cerebral infarction.展开更多
Objective:To analyze the correlation between serum Hcy content and coronary atherosclerosis severity in patients with H-type hypertension and coronary heart disease. Methods: 48 patients with H-type hypertension and c...Objective:To analyze the correlation between serum Hcy content and coronary atherosclerosis severity in patients with H-type hypertension and coronary heart disease. Methods: 48 patients with H-type hypertension and coronary heart disease were selected as observation group, and 57 patients with normal hypertension and coronary heart disease were selected as control group. Echocardiography was used to determine coronary lesion parameters, enzyme-linked immunosorbent assay (ELISA) was used to determine serum levels of homocysteine (Hcy) and coronary heart disease-related indexes, and the correlation between Hcy levels and coronary heart disease was further analyzed. Results:Serum Hcy level of observation group was higher than that of control group (P<0.05), absolute GLPSS value and E/A value under echocardiography were less than those of control group while E-DT and E/e value were higher than those of control group (P<0.05);serum adiponectin (APN) level was lower than that of control group while P-selectin, asymmetric dimethylarginine (ADMA), oxidized high-density lipoprotein (OX-HDL), MMP-2, MMP-9, lipoprotein-associated phospholipase A2 (Lp-PLA2) and Resistin levels were higher than those of control group (P<0.05);Hcy was negatively correlated with absolute GLPSS value, E/A value and APN level, and was positively correlated with E-DT value, E/e value as well as P-selectin, ADMA, OX-HDL, MMP-2, MMP-9, Lp-PLA2 and Resistin levels (P<0.05). Conclusions:There is direct correlation between serum Hcy levels and the severity of coronary heart disease in patients with H-type hypertension and coronary heart disease, it can be a reliable way to early screen for coronary heart disease and evaluate the illness, and it is also a new target of coronary heart disease intervention.展开更多
Objective:To explore the effect of folic acid combined with routine drugs on Hcy metabolism, inflammatory response and plaque properties in patients with H-type hypertension complicated by carotid atherosclerosis.Meth...Objective:To explore the effect of folic acid combined with routine drugs on Hcy metabolism, inflammatory response and plaque properties in patients with H-type hypertension complicated by carotid atherosclerosis.Methods: A total of 68 patients with H-type hypertension complicated by carotid atherosclerosis who received treatment in our hospital between January 2014 and September 2016 were collected and divided into control group (n=34) and observation group (n=34) according to random number table. The control group received routine therapy and the observation group received folic acid combined with routine drug therapy. The differences in Hcy metabolism, inflammatory response and plaque properties were compared between the two groups of patients before and after treatment.Results:Before treatment, differences in serum Hcy contents, pro-inflammatory and anti-inflammatory mediator contents, and ultrasound plaque property parameter levels were not statistically significant between two groups of patients. After treatment, serum Hcy content of observation group was lower than that of control group;serum pro-inflammatory factors IL-1, IL-6, IL-8 and CRP contents were lower than those of control group;serum anti-inflammatory factors IL-4, IL-10 and IL-13 contents were lower than those of control group;ultrasound plaque property parameter strain value was lower than that of control group while plaque strain rate was higher than that of control group.Conclusion:Folic acid treatment based on routine treatment can effectively accelerate the Hcy metabolism, reduce systemic inflammatory response and increase the plaque stability in patients with H-type hypertension complicated by carotid atherosclerosis.展开更多
Objective:To explore the correlation of carotid IMT (cIMT) with Hcy, Cyst-C, UA, and Lp(a) in middle-aged patients with H-type hypertension.Methods:A total of 120 middle-aged patients with H-type hypertension who were...Objective:To explore the correlation of carotid IMT (cIMT) with Hcy, Cyst-C, UA, and Lp(a) in middle-aged patients with H-type hypertension.Methods:A total of 120 middle-aged patients with H-type hypertension who were admitted in our hospital from July, 2015 to July, 2016 were included in the study. The color Doppler ultrasound diagnostic apparatus was used for the two-dimensional ultrasound examination. The patients were divided into the normal group, thickening group, and plaque group with 40 cases in each group according to the atherosclerosis (AS). The full automatic biochemical analyzer was used to detect the plasma Hcy, Cyst-C, UA, Scr, Bun, TC, TG, LDL-C, and HDL-C. Emulsion turbidity method was used to detect Lp(a).Results:With the thickening of cIMT, Hcy, Cyst-C, Lp(a), and UA levels were elevated, while HDL-C level was reduced.Conclusions:The serum Hcy, Cyst-C, UA, and Lp(a) levels in middle-aged patients with H-type hypertension are positively correlated with cIMT, are the independent risk factors for developing AS, and can be served as the early indicators to estimate the occurrence and development of AS.展开更多
Tetrasulfonated Zn,Co,Ga,In,TiO and metal free phthalocyanine (MTsPc) mainly exist as dimers on the nanostructured TiO 2 electrode and mostly exist as monomers in dimethyl sulfoxide. The photocurrent action spectra ...Tetrasulfonated Zn,Co,Ga,In,TiO and metal free phthalocyanine (MTsPc) mainly exist as dimers on the nanostructured TiO 2 electrode and mostly exist as monomers in dimethyl sulfoxide. The photocurrent action spectra of the liquid junction based on the MTsPc/TiO 2 nanostructured electrode show that only the absorbance of the MTsPc monomer contributes to a photocurrent while that of the MTsPc face to face dimer does not generate a photocurrent.展开更多
This paper focuses on constructing the adaptive analysis model based on the Finite Element Method(FEM)with an unstructured mesh,which includes taking full advantage of the two-dimensional triangle’s ability to discre...This paper focuses on constructing the adaptive analysis model based on the Finite Element Method(FEM)with an unstructured mesh,which includes taking full advantage of the two-dimensional triangle’s ability to discretize any complex model.The error indicator and h-type refinement scheme for FEM has been presented by providing a simple error indicator based on the difference value of nodal fundamental physical variables.It provides an effective measure of the error in the numerical solution,which can lead to an adaptive refinement scheme,determining the optimal location of new inserted nodes that are mainly distributed in the local high stress gradient domain.A numerical experiment is presented to demonstrate that the proposed error indicator reasonably tracks the distribution of the true error,and the effectiveness of the proposed adaptive analysis procedure,which achieves significantly higher convergence rates compared to the uniform mesh.展开更多
基金National Natural Science Foundation of China (81973749 and 8143594)State Administration of Traditional Chinese Medicine High-level Chinese Medicine Key Discipline Construction Project (zyyzdxk-2023069)。
文摘Objective To develop an onset risk prediction nomogram for patients with homocysteine-type(H-type)hypertension(HTH)based on pulse diagram parameters to assist early clinical prediction and diagnosis of HTH.Methods Patients diagnosed with essential hypertension and admitted to Shanghai Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shang-hai Hospital of Traditional Chinese Medicine,and Shanghai Hospital of Integrated Tradition-al Chinese and Western Medicine from July 6th 2020 to June 16th 2021,and from August 11th 2023 to January 22nd 2024,were enrolled in this retrospective research.The baselines and clinical biochemical indicators of patients were collected.The SMART-I TCM pulse instru-ment was applied to gather pulse diagram parameters.Multivariate logistic regression was adopted to analyze the risk factors for HTH.RStudio was employed to construct the nomo-gram model,receiver operating characteristic(ROC)curve,and calibration curve(bootstrap self-sampling 200 times),and clinical decision curve were drawn to evaluate the model’s dis-crimination and clinical effectiveness.Results A total of 168 hospitalized patients with essential hypertension were selected and di-vided into non-HTH group(n=29)and HTH group(n=139).Compared with non-HTH group,HTH group had a lower body mass index(BMI),and higher proportions of male pa-tients and drinkers(P<0.05).The ventricular wall thickening(VWT)could not be deter-mined.The proportions of left common carotid intima-media wall thickness(LCCIMWT)and serum creatinine(SCR)were higher in HTH group(P<0.05).The pulse diagram parameter As was significantly higher,and H4/H1 and T1/T were lower in HTH group(P<0.05).Gender,al-cohol consumption,serum creatinine,and the pulse diagram parameter H4/H1 were identi-fied as independent risk factors for HTH(P<0.05).The nomogram’s area under the ROC curve(AUC)was 0.795[95%confidence interval(CI):(0.7066,0.8828)],with a specificity of 0.724 and sensitivity of 0.799.After 200 times repeated bootstrap self-samplings,the calibra-tion curve showed that the simulated curve fits well with the actual curve(x^(2)=9.5002,P=0.3019).The clinical decision curve indicated that the nomogram’s applicability was optimal when the threshold for predicting HTH was between 0.38 and 1.00.Conclusion The nomogram model could be valuable for predicting the onset risk of HTH and pulse diagram parameters can facilitate early screening and prevention of HTH.
基金the Science,Technology and Innovation Commission of Shenzhen Municipality of China(Nos.JCYJ20170306160003433 and JCYJ20180306171058717)111 Project of China(No.B08040)for the support given to this research。
文摘The bent double-ridged rectangular tube(DRRT)with high forming quality is helpful to improve the microwave transmission accuracy.For reducing the cross-sectional deformation in the H-typed bending process,in addition to using rigid mandrel to support the inside of tube,ridge groove fillers are also added to restrict the deformation of ridge grooves.Because of the change of stress and strain state of bent tube in bending,rigid mandrel retracting and specially twicespringback stages,and the springback of fillers,the cross-sectional deformation of tube in each stage may be different.Therefore,based on the ABAQUS platform,the finite element models(FEM)for H-typed bending,mandrel retracting and twice-springback stages of H96 DRRT with fillers were established and validated.It is found that,for the height and width deformation of tube and spacing deformation of ridge grooves,retraction of mandrel can make the distribution of these deformations more uniform along the bending direction.The first springback can reduce these deformations significantly,which should be emphasized.But the second springback only increases them by less amount,which can be ignored.The smaller height deformation of ridge groove and filler can be neglected.
基金supported by National Nature Science Foundation of China(11371036)
文摘Let △ be full Laplacian on H-type group G. Then for every compact set D Ga local estimate of the Schrodinger maximal operator holds, that is,∫D^sup0〈t〈1｜e^it△f（x）｜^2dx≤｜｜f｜｜^2H^s,s〉1/2We also show that the above inequality fails when s 〈 1/4.
基金financial support from the National Natural Science Foundation of China(No.20134020)the Science Research Fund of the Chinese Ministry of Education(No.104005)the Science Research Fund of Shandong Provincial Education Department of China(No.105D11).
文摘H-type amphiphilic liquid crystalline block copolymers containing azobenzene were synthesized by atom transfer radical polymerization （ATRP）. Macroinitiators prepared by the esterification between poly（ethylene oxide） （PEG） and 2,2-dichloroacetyl chloride were utilized to initiate the polymerization of 6-[4-（4-ethoxyphenylazo）phenoxy]hexyl rnethacrylate （M6C）. The resulting macroinitiators and block copolymers were characterized by ^1H NMR, gel permeation chromatography （GPC）. Polarizing optical microscopy （POM） and differential scanning calorimetry （DSC） preliminarily revealed the liquid crystalline property of these block copolymers. This series of liquid crystalline block copolymers are promising in some areas, such as optical data storage, optical switch, and molecular devices.
基金supported by the National Natural Science Foundation of China(Grant Nos.41672273,42177137)the Fundamental Research Funds for the Central Universities(22120180313)+1 种基金the support from China Scholarship Council(CSC)(202106260151)substantially supported by the Key Laboratory of Geotechnical and Underground Engineering of Ministry of Education(Tongji University)。
文摘Due to the loose structure,high porosity and high permeability of soil-rock mixture slope,the slope is unstable and may cause huge economic losses and casualties.The h-type anti-slide pile is regarded as an effective means to prevent the instability of soilrock mixture slope.In this paper,a centrifuge model test was conducted to investigate the stress distribution of the h-type anti-slide pile and the evolution process of soil arching during the loading.A numerical simulation model was built based on the similar relationship between the centrifuge model and the prototype to investigate the influence factors of the pile spacing,anchored depth,and crossbeam stiffness,and some recommendations were proposed for its application.The results show that the bending moment distribution of the rear pile exhibits Wshaped,while for the front pile,its distribution resembles V-shaped.The soil arching evolution process during loading is gradually dissipated from bottom to top and from far to near.During the loading,the change of bending moment can be divided into three stages,namely,the stabilization stage,the slow growth stage,and the rapid growth stage.In engineering projects,the recommended values of the pile spacing,anchored depth,and crossbeam stiffness are 4.0d,2.0d,and 2.0EI,where d and EI are the diameter and bending stiffness of the h-type anti-slide pile respectively.
文摘H-type zeolites（ HY, Hβ, and HM） were synthesized and characterized by XRD, NH3-TPD, and Py-IR. Selectively catalytic alkylation of naphthalene with n-hexanol to hexyl-naphthalene over the zeolites was carried out. The experimental results show that the catalytic activities of the zeolites are mainly determined by their acid properties and pore structures. The larger the pore diameter is, the higher the catalytic activity is. NH3-TPD profiles show that Hβ and HM have lower acid strengths than HY. HY has both the highest activity and highest selectivity for the hexylnaphthalene. Higher reaction temperatures and longer reaction time are beneficial to the production of β-hexyl-naphthalene over the HY zeolite.
文摘Objective:To study the relationship between serum inflammatory response cytokines and the change of plaque properties in patients with H-type hypertension complicated by carotid atherosclerosis.Methods: Patients who were diagnosed with H-type hypertension complicated by carotid atherosclerosis in Yulin Hospital of Traditional Chinese Medicine between May 2014 and December 2016 were selected as group A, patients with H-type hypertension complicated by carotid atherosclerosis and normal Hcy levels were selected as group B, patients with carotid atherosclerosis and normal blood pressure levels and Hcy levels were selected as group C, and healthy volunteers during the same period were selected as control group. Serum levels of inflammatory response cytokines and plaque property-related cytokines were detected.Results: Serum Hcy, sICAM-1, MCP-1, YKL-40, IL-6, PTX3, FGF23, MMP9 and Caspase-3 levels of group A, group B and group C were significantly higher than those of group D, serum Hcy, sICAM-1, MCP-1, YKL-40, IL-6, PTX3, FGF23, MMP9 and Caspase-3 levels of group A and group B were significantly higher than those of group C, and serum Hcy, sICAM-1, MCP-1, YKL-40, IL-6, PTX3, FGF23, MMP9 and Caspase-3 levels of group A were significantly higher than those of group B;serum Hcy, sICAM-1, MCP-1, YKL-40, IL-6, PTX3, FGF23, MMP9 and Caspase-3 levels of group A with vulnerable plaques were significantly higher than those of patients with stable plaques. Serum Hcy, sICAM-1, MCP-1, YKL-40 and IL-6 levels of group A were positively correlated with PTX3, FGF23, MMP9 and Caspase-3 levels.Conclusion: Serum inflammatory response cytokine secretion increases in patients with H-type hypertension complicated by carotid atherosclerosis, and it can result in the change in plaque properties and the decrease in stability.
文摘Purpose: To show for which publication-citation arrays h-type indices are equal and to reconsider rational h-type indices. Results for these research questions fill some gaps in existing basic knowledge about h-type indices.Design/methodology/approach: The results and introduction of new indicators are based on well-known definitions.Findings: The research purpose has been reached: answers to the first questions are obtained and new indicators are defined. Research limitations: h-type indices do not meet the Bouyssou-Marchant independence requirement.Practical implications: On the one hand, more insight has been obtained for well-known indices such as the h-and the g-index and on the other hand, simple extensions of existing indicators have been added to the bibliometric toolbox. Relative rational h-type indices are more useful for individuals than the existing absolute ones.Originality/value: Answers to basic questions such as "when are the values of two h-type indices equal" are provided. A new rational h-index is introduced.
基金supported by National Science Foundation of China (10571044)
文摘This article obtains an explicit expression of the heat kernels on H-type groups and then follow the estimate of heat kernels to deduce the Hardy＇s uncertainty principle on the nilpotent Lie groups.
基金This study was supported by the following research funding.Natural Science Foundation of Anhui Province,China,Grant Number 1908085ME166Research on the Key Technology of Multipole Grain Sampling and Inspection Equipment Based on Machine Vision,Anhui Provincial Grain Machinery Rural Development Collaborative Technology Service Center,Grant Number GXXT-2022-077+3 种基金Research on the Preparation Process and Application of Biochar Made of Bamboo,Science and Technology Bureau of Chuzhou City,Grant Number 2022ZN014The Development and Industrialization of Fruit Sorting Equipment,Science and Technology Bureau of Chuzhou City,Grant Number 2022ZN016Natural Science Major Project of Anhui Provincial Education Department,Anhui Provincial Education Department,Grant Number 2022AH040238Key Scientific Research Project of Anhui Provincial Education Department,Anhui Provincial Education Department,Grant Number KJ2021A0877.
文摘Numerical simulations are conducted to improve the energy acquisition efficiency of H-type vertical axis wind turbines through the optimization of the related blade airfoil aerodynamic performance.The Bézier curve is initi-ally used tofit the curve profile of a NACA2412 airfoil,and the moving asymptote algorithm is then exploited to optimize the design of the considered H-type vertical-axis wind-turbine blade airfoil for a certain attack angle.The results show that the maximum lift coefficient of the optimized airfoil is 8.33%higher than that of the original airfoil.The maximum lift-to-drag ratio of the optimized airfoil exceeds the maximum lift-to-drag ratio of the ori-ginal airfoil by 11.22%.Moreover,the power coefficient is increased by 12.19%and the torque coefficient of the wind turbine is significantly improved.
基金Supported by the National Natural Science Foundation of China under Grant No 51372203the National Basic Research Program of China under Grant No 2011CB605806+1 种基金the Basic Research Foundation of Northwestern Polytechnical University under Grant Nos JCY20130114 and JCY20110248the Foreign Talents Introduction and Academic Exchange Program under Grant No B08040
文摘Structural, electronic and mechanical properties of the nH-SiC （n = 2, 4, 6, 8 and 10） polytypes are calculated by using the first-principles calculations based on the density-functional theory approach. The optimized lattice parameters of nH-SiC are in good agreement with the experimental data. The mechanical properties, including elastic constants, bulk modulus, Young＇s modulus, shear modulus and Poisson＇s ratio, are calculated. The analysis of elastic properties indicates that the effects of n on the mechanical properties of the five nil-SiC structures have no difference. The indirect band gap relationship for the live polytypes is Ebg2H 〉 Ebg4H 〉 Ebg6H 〉 Ebg10H 〉 EbgsH.
文摘Objective:To explore the correlation of carotid intima media thickness with function in patients with H-type hypertension and acute cerebral infarction.Methods:A total of 150 patients with acute cerebral infarction who were admitted in our hospital from June, 2016 to June, 2017 were included in the study and divided into H-type hypertension group (H-type hypertension merged with acute cerebral infarction, Hcy≥10 μmol/L), non-H-type hypertension group (non- H-type hypertension merged with acute cerebral infarction, Hcy≥10 μmol/L), and the control group (no hypertension but with acute cerebral infarction) according to Hcy level and whether being suffered from hypertension or not with 50 cases in each group. Moreover, 50 healthy individuals who came for physical examinations were served as the healthy group. The morning fasting peripheral venous blood was collected at physical examination time for patients in the healthy group and after admission for patients with acute cerebral infarction. Hcy, sICAM-1, MCP-1, and YKL-40 were detected. The color Doppler ultrasound diagnostic apparatus was used to detect IMT, distensibility, and stiffness. Results: Hcy, MCP-1, sICAM-1, and YKL-40 levels in H-type hypertension group, non-H-type hypertension group, and the control group were significantly higher than those in the healthy group. Hcy, MCP-1, sICAM-1, and YKL-40 levels in H-type hypertension group and non-H-type hypertension group were significantly higher than those in the control group. Hcy, MCP-1, sICAM-1, and YKL-40 levels in H-type hypertension group were significantly higher than those in non-H-type hypertension group. IMT and stiffness in H-type hypertension group, non-H-type hypertension group, and the control group were significantly greater than those in the healthy group, while distensibility was significantly less than that in the healthy group. IMT and stiffness in H-type hypertension group and non-H-type hypertension group were significantly greater than those in the control group, while distensibility was significantly less than that in the control group. IMT and stiffness in H-type hypertension group were significantly greater than those in non-H-type hypertension group, while distensibility was significantly less than that in non-H-type hypertension group.Conclusions: Hcy can directly affect carotid AS, increase carotid IMT, and promote the occurrence of hypertension merged with acute cerebral infarction;therefore, positive monitoring of serum Hcy level and IMT thickness in patients with hypertension and acute cerebral infarction and early intervention are of great significance in reducing the occurrence of carotid AS, delaying the progression of carotid AS, and preventing hypertension and acute cerebral infarction.
文摘Objective:To analyze the correlation between serum Hcy content and coronary atherosclerosis severity in patients with H-type hypertension and coronary heart disease. Methods: 48 patients with H-type hypertension and coronary heart disease were selected as observation group, and 57 patients with normal hypertension and coronary heart disease were selected as control group. Echocardiography was used to determine coronary lesion parameters, enzyme-linked immunosorbent assay (ELISA) was used to determine serum levels of homocysteine (Hcy) and coronary heart disease-related indexes, and the correlation between Hcy levels and coronary heart disease was further analyzed. Results:Serum Hcy level of observation group was higher than that of control group (P<0.05), absolute GLPSS value and E/A value under echocardiography were less than those of control group while E-DT and E/e value were higher than those of control group (P<0.05);serum adiponectin (APN) level was lower than that of control group while P-selectin, asymmetric dimethylarginine (ADMA), oxidized high-density lipoprotein (OX-HDL), MMP-2, MMP-9, lipoprotein-associated phospholipase A2 (Lp-PLA2) and Resistin levels were higher than those of control group (P<0.05);Hcy was negatively correlated with absolute GLPSS value, E/A value and APN level, and was positively correlated with E-DT value, E/e value as well as P-selectin, ADMA, OX-HDL, MMP-2, MMP-9, Lp-PLA2 and Resistin levels (P<0.05). Conclusions:There is direct correlation between serum Hcy levels and the severity of coronary heart disease in patients with H-type hypertension and coronary heart disease, it can be a reliable way to early screen for coronary heart disease and evaluate the illness, and it is also a new target of coronary heart disease intervention.
文摘Objective:To explore the effect of folic acid combined with routine drugs on Hcy metabolism, inflammatory response and plaque properties in patients with H-type hypertension complicated by carotid atherosclerosis.Methods: A total of 68 patients with H-type hypertension complicated by carotid atherosclerosis who received treatment in our hospital between January 2014 and September 2016 were collected and divided into control group (n=34) and observation group (n=34) according to random number table. The control group received routine therapy and the observation group received folic acid combined with routine drug therapy. The differences in Hcy metabolism, inflammatory response and plaque properties were compared between the two groups of patients before and after treatment.Results:Before treatment, differences in serum Hcy contents, pro-inflammatory and anti-inflammatory mediator contents, and ultrasound plaque property parameter levels were not statistically significant between two groups of patients. After treatment, serum Hcy content of observation group was lower than that of control group;serum pro-inflammatory factors IL-1, IL-6, IL-8 and CRP contents were lower than those of control group;serum anti-inflammatory factors IL-4, IL-10 and IL-13 contents were lower than those of control group;ultrasound plaque property parameter strain value was lower than that of control group while plaque strain rate was higher than that of control group.Conclusion:Folic acid treatment based on routine treatment can effectively accelerate the Hcy metabolism, reduce systemic inflammatory response and increase the plaque stability in patients with H-type hypertension complicated by carotid atherosclerosis.
文摘Objective:To explore the correlation of carotid IMT (cIMT) with Hcy, Cyst-C, UA, and Lp(a) in middle-aged patients with H-type hypertension.Methods:A total of 120 middle-aged patients with H-type hypertension who were admitted in our hospital from July, 2015 to July, 2016 were included in the study. The color Doppler ultrasound diagnostic apparatus was used for the two-dimensional ultrasound examination. The patients were divided into the normal group, thickening group, and plaque group with 40 cases in each group according to the atherosclerosis (AS). The full automatic biochemical analyzer was used to detect the plasma Hcy, Cyst-C, UA, Scr, Bun, TC, TG, LDL-C, and HDL-C. Emulsion turbidity method was used to detect Lp(a).Results:With the thickening of cIMT, Hcy, Cyst-C, Lp(a), and UA levels were elevated, while HDL-C level was reduced.Conclusions:The serum Hcy, Cyst-C, UA, and Lp(a) levels in middle-aged patients with H-type hypertension are positively correlated with cIMT, are the independent risk factors for developing AS, and can be served as the early indicators to estimate the occurrence and development of AS.
文摘Tetrasulfonated Zn,Co,Ga,In,TiO and metal free phthalocyanine (MTsPc) mainly exist as dimers on the nanostructured TiO 2 electrode and mostly exist as monomers in dimethyl sulfoxide. The photocurrent action spectra of the liquid junction based on the MTsPc/TiO 2 nanostructured electrode show that only the absorbance of the MTsPc monomer contributes to a photocurrent while that of the MTsPc face to face dimer does not generate a photocurrent.
基金supported by the Hunan Provincial Natural Science Foundation of China.(Grant No.2023JJ50222).
文摘This paper focuses on constructing the adaptive analysis model based on the Finite Element Method(FEM)with an unstructured mesh,which includes taking full advantage of the two-dimensional triangle’s ability to discretize any complex model.The error indicator and h-type refinement scheme for FEM has been presented by providing a simple error indicator based on the difference value of nodal fundamental physical variables.It provides an effective measure of the error in the numerical solution,which can lead to an adaptive refinement scheme,determining the optimal location of new inserted nodes that are mainly distributed in the local high stress gradient domain.A numerical experiment is presented to demonstrate that the proposed error indicator reasonably tracks the distribution of the true error,and the effectiveness of the proposed adaptive analysis procedure,which achieves significantly higher convergence rates compared to the uniform mesh.
