The Old Man and the Sea is one of the masterpieces of Hemingway,which describes the old fisherman Santiago is always collected in the presence of danger and maintains a high level of dignity in the struggle with natur...The Old Man and the Sea is one of the masterpieces of Hemingway,which describes the old fisherman Santiago is always collected in the presence of danger and maintains a high level of dignity in the struggle with nature. DiMaggio does not really appear in the novel,but the role he plays in the novel is very important. This article discusses the subtle and indispensable role he plays based on the dialogues between the child and Santiago and his inner activities when fighting with the marlin and the shark at the sea.展开更多
目的比较S. T. O. N. E.肾结石评分与Guy肾结石分级对经皮肾镜取石术(percutaneous nephroscope lithoipsy,PCNL)结石清除率预测的准确性。方法选择2015-01至2017-12在西安交通大学第二附属医院接受PCNL的患者146例,术前分别进行S. T. O...目的比较S. T. O. N. E.肾结石评分与Guy肾结石分级对经皮肾镜取石术(percutaneous nephroscope lithoipsy,PCNL)结石清除率预测的准确性。方法选择2015-01至2017-12在西安交通大学第二附属医院接受PCNL的患者146例,术前分别进行S. T. O. N. E.评分和Guy分级。术后统计结石清除率,分别计算S. T. O. N. E.评分和Guy分级的ROC曲线下面积,对比两种方法预测的准确性。结果结石清除率为73. 97%。S. T. O. N. E.肾结石评分预测PCNL术后结石清除率的准确性为74. 8%,最佳阈值为8. 5分,灵敏度为73. 7%,特异度为71. 3%; Guy分级预测PCNL术后结石清除率的准确性为71. 5%,最佳阈值为2. 5级,灵敏度为71. 1%,特异度为64. 8%。两种方法的ROC曲线下面积分别为0. 748和0. 715,无统计学差异。结论 S. T. O. N. E.评分与Guy分级均具有中等水平预测能力,均可用来评估PCNL术后结石清除率,两个方法的预测能力未见统计学差别。展开更多
The receptor for advanced glycation endproducts（RAGE）is a receptor of the immunoglobulin superfamily of cell surface molecules which plays important contributions under both physiological and pathological conditions...The receptor for advanced glycation endproducts（RAGE）is a receptor of the immunoglobulin superfamily of cell surface molecules which plays important contributions under both physiological and pathological conditions.Over the years extensive research work supported the detrimental role of RAGE in Alzheimer’s disease（AD）pathophysiology,ranging from its involvement in beta amyloid（Aβ）brain influx and clearance,展开更多
Grain number and seed-setting rate are components of crop yield.Cytokinin influences grain yield.However,emerging studies suggest that high cytokinin signals often lead to reduced branching or seed-setting rate,leadin...Grain number and seed-setting rate are components of crop yield.Cytokinin influences grain yield.However,emerging studies suggest that high cytokinin signals often lead to reduced branching or seed-setting rate,leading to reduced grain yield,although the mechanisms remain unclear.In this study,we identified and characterized the rice(Oryza sativa L.)gene LONELY GUY-LIKE 8(LOGL8),based on analysis of the LOGL8-pm(promoter mutant of LOGL8)mutant,which harbors a T-DNA insertion in the promoter of this gene.The mutation in LOGL8-pm causes ectopic hyperexpression of LOGL8 in inflorescence organs,resulting in plants with smaller panicles and defective ovules lacking archesporial cells and integuments.Knockout of LOGL8 caused pollen abortion,leading to a reduced seed-setting rate.LOGL8 encodes a putative cytokinin-activating enzyme.Our results showed that LOGL8 directly catalyzes the biosynthesis of bioactive cytokinins.Therefore,we propose that the ectopic expression of LOGL8 disrupts cytokinin spatiotemporal distribution and causes inhibition of LONELY GUY(LOG),which affects panicle branching and female organ development.These findings reveal the important role of LOGL8 in male development,and highlight the delicate balance of local cytokinin levels during panicle branching and female organ development.展开更多
The following essay aims to critically discuss the first transposition of Guy de Maupassant’s novel Bel-Ami to the screen by Austrian film director Willi Forst at the end of the 1930s.Forst’s film preceded by a deca...The following essay aims to critically discuss the first transposition of Guy de Maupassant’s novel Bel-Ami to the screen by Austrian film director Willi Forst at the end of the 1930s.Forst’s film preceded by a decade Hollywood’s version The Private Affairs of Bel Ami,of 1947,with George Sanders as Bel-Ami,while Maupassant’s novel was first brought to the screen in France by Louis Daquin in the 1950s.Yet Forst’s film has been paid but scarce attention in scholarly studies on the cinematic adaptations of Maupassant’s work.In discussing Forst’s film,the present essay will specifically examine Forst’s work in its relation to Maupassant’s novel.In particular,attention will be focused on the metamorphosis of the character of Bel-Ami on the screen in comparison to the novel,and Forst’s film shall simultaneously be analyzed in the context of Forst’s oeuvre.By drawing attention to the first film to be adapted from Maupassant’s world-famous novel,this essay aims to fill a gap in scholarly literature on the relationship between the French novelist and cinema.展开更多
The Old Man and The Sea written by Hemingway, is one of the famous novel in the world. In the novel, the writer describes an old man Santiago. He has a very famous saying:"A man can be destroyed but not defeated....The Old Man and The Sea written by Hemingway, is one of the famous novel in the world. In the novel, the writer describes an old man Santiago. He has a very famous saying:"A man can be destroyed but not defeated." In my opinion, he is neither destroyed nor defeated. He is a man with high dignity. He is the one who can give when he can and receive when he needs. He is a man full of high spiritual qualities and these can be passed on to the next generation.展开更多
LONELY GUY(LOG)is a pivotal cytokinin-activating enzyme that plays an important role in plant growth,development,and stress responses.Walnut(Juglans regia),an important woody oilseed species,has not yet undergone syst...LONELY GUY(LOG)is a pivotal cytokinin-activating enzyme that plays an important role in plant growth,development,and stress responses.Walnut(Juglans regia),an important woody oilseed species,has not yet undergone systematic identification of its LOG gene family.In this study,we identified 17 JrLOG genes in the walnut genome,which are unevenly distributed across 11 chromosomes.JrLOG gene expansion was primarily driven by gene duplication,along with purifying selection.Members of the JrLOG family were categorized into five groups,each exhibiting analogous gene structures,featured motifs,and conserved domains.Transcriptome and quantitative real-time PCR analyses revealed that JrLOG gene expression was tissue-specific,developmentally regulated,and responsive to stress situations.Notably,JrLOG3,which localizes to the cell membrane,exhibited high expression levels in leaves and responded to both cold and pathogen infection treatments.This study represents the first comprehensive identification of the LOG gene family in walnut,offering essential data for further functional studies of this gene family.展开更多
Literary characters possess a genealogy.Indeed,stock characters like the evil genius or super villain boast family trees that readers can trace not only through time--in this case,starting in the late 19th century--bu...Literary characters possess a genealogy.Indeed,stock characters like the evil genius or super villain boast family trees that readers can trace not only through time--in this case,starting in the late 19th century--but also across borders.This study traces the genealogical roots of the modern super villain by examining,in turn,Ian Fleming's characters Ernst Blofeld and Dr.Julius No,Sax Rohmer's Dr.Fu Manchu,and Guy Boothby's Dr.Antonio Nikola.In"Orientalism",the author contends that the modern super villain is the embodiment of these writers'orientalist fantasies and fears.Finally,in"Mad Science",the argument is made that the evil geniuses of Fleming,Rohmer,and Boothby may very well be the offspring of an earlier stock character,the mad scientist,who trades monomania for megalomania.展开更多
guy是英语口语中较常用的一个单词。一般词典给它的释义大都是a boy或a young man。但是在美国,常会听到一些女学生也相互称呼guys。查一下Dictionary of American Slang,里面确实有a person of either的释义。但以上两种释义都没有对gu...guy是英语口语中较常用的一个单词。一般词典给它的释义大都是a boy或a young man。但是在美国,常会听到一些女学生也相互称呼guys。查一下Dictionary of American Slang,里面确实有a person of either的释义。但以上两种释义都没有对guy一词单数和复数不同的用法加以区别。在实际应用中,guy一词做单数使用时是做a boy或a man 解。展开更多
The intrinsic and extrinsic features of the father in The Road as a"Tough Guy"are to be analyzed. For the inner world, heis calm towards the living environments, decisive when faced the emergency and persist...The intrinsic and extrinsic features of the father in The Road as a"Tough Guy"are to be analyzed. For the inner world, heis calm towards the living environments, decisive when faced the emergency and persistent in dignity and morality. For the actions,he is active in seeking foods, brave in fighting with the enemies and gentle with his son. Finally, the conclusion is drawn that the fa-ther is a"Tough Guy".展开更多
文摘The Old Man and the Sea is one of the masterpieces of Hemingway,which describes the old fisherman Santiago is always collected in the presence of danger and maintains a high level of dignity in the struggle with nature. DiMaggio does not really appear in the novel,but the role he plays in the novel is very important. This article discusses the subtle and indispensable role he plays based on the dialogues between the child and Santiago and his inner activities when fighting with the marlin and the shark at the sea.
文摘目的比较S. T. O. N. E.肾结石评分与Guy肾结石分级对经皮肾镜取石术(percutaneous nephroscope lithoipsy,PCNL)结石清除率预测的准确性。方法选择2015-01至2017-12在西安交通大学第二附属医院接受PCNL的患者146例,术前分别进行S. T. O. N. E.评分和Guy分级。术后统计结石清除率,分别计算S. T. O. N. E.评分和Guy分级的ROC曲线下面积,对比两种方法预测的准确性。结果结石清除率为73. 97%。S. T. O. N. E.肾结石评分预测PCNL术后结石清除率的准确性为74. 8%,最佳阈值为8. 5分,灵敏度为73. 7%,特异度为71. 3%; Guy分级预测PCNL术后结石清除率的准确性为71. 5%,最佳阈值为2. 5级,灵敏度为71. 1%,特异度为64. 8%。两种方法的ROC曲线下面积分别为0. 748和0. 715,无统计学差异。结论 S. T. O. N. E.评分与Guy分级均具有中等水平预测能力,均可用来评估PCNL术后结石清除率,两个方法的预测能力未见统计学差别。
文摘The receptor for advanced glycation endproducts（RAGE）is a receptor of the immunoglobulin superfamily of cell surface molecules which plays important contributions under both physiological and pathological conditions.Over the years extensive research work supported the detrimental role of RAGE in Alzheimer’s disease（AD）pathophysiology,ranging from its involvement in beta amyloid（Aβ）brain influx and clearance,
基金supported by the National Natural Science Foundation of China(31991222,32030080,31271301)the Guangdong Basic and Applied Basic Research Founation(2020A1515110207)the China Postdoctoral Science Foundation(2020M682726)。
文摘Grain number and seed-setting rate are components of crop yield.Cytokinin influences grain yield.However,emerging studies suggest that high cytokinin signals often lead to reduced branching or seed-setting rate,leading to reduced grain yield,although the mechanisms remain unclear.In this study,we identified and characterized the rice(Oryza sativa L.)gene LONELY GUY-LIKE 8(LOGL8),based on analysis of the LOGL8-pm(promoter mutant of LOGL8)mutant,which harbors a T-DNA insertion in the promoter of this gene.The mutation in LOGL8-pm causes ectopic hyperexpression of LOGL8 in inflorescence organs,resulting in plants with smaller panicles and defective ovules lacking archesporial cells and integuments.Knockout of LOGL8 caused pollen abortion,leading to a reduced seed-setting rate.LOGL8 encodes a putative cytokinin-activating enzyme.Our results showed that LOGL8 directly catalyzes the biosynthesis of bioactive cytokinins.Therefore,we propose that the ectopic expression of LOGL8 disrupts cytokinin spatiotemporal distribution and causes inhibition of LONELY GUY(LOG),which affects panicle branching and female organ development.These findings reveal the important role of LOGL8 in male development,and highlight the delicate balance of local cytokinin levels during panicle branching and female organ development.
文摘The following essay aims to critically discuss the first transposition of Guy de Maupassant’s novel Bel-Ami to the screen by Austrian film director Willi Forst at the end of the 1930s.Forst’s film preceded by a decade Hollywood’s version The Private Affairs of Bel Ami,of 1947,with George Sanders as Bel-Ami,while Maupassant’s novel was first brought to the screen in France by Louis Daquin in the 1950s.Yet Forst’s film has been paid but scarce attention in scholarly studies on the cinematic adaptations of Maupassant’s work.In discussing Forst’s film,the present essay will specifically examine Forst’s work in its relation to Maupassant’s novel.In particular,attention will be focused on the metamorphosis of the character of Bel-Ami on the screen in comparison to the novel,and Forst’s film shall simultaneously be analyzed in the context of Forst’s oeuvre.By drawing attention to the first film to be adapted from Maupassant’s world-famous novel,this essay aims to fill a gap in scholarly literature on the relationship between the French novelist and cinema.
文摘The Old Man and The Sea written by Hemingway, is one of the famous novel in the world. In the novel, the writer describes an old man Santiago. He has a very famous saying:"A man can be destroyed but not defeated." In my opinion, he is neither destroyed nor defeated. He is a man with high dignity. He is the one who can give when he can and receive when he needs. He is a man full of high spiritual qualities and these can be passed on to the next generation.
基金supported by the Special Scientific Research Project for the Introduction of Talents in Hebei Agricultural University(YJ2021026)the Construction of Innovation Team of Modern Agricultural Industry Technology System in Hebei Province(HBCT2021100211).
文摘LONELY GUY(LOG)is a pivotal cytokinin-activating enzyme that plays an important role in plant growth,development,and stress responses.Walnut(Juglans regia),an important woody oilseed species,has not yet undergone systematic identification of its LOG gene family.In this study,we identified 17 JrLOG genes in the walnut genome,which are unevenly distributed across 11 chromosomes.JrLOG gene expansion was primarily driven by gene duplication,along with purifying selection.Members of the JrLOG family were categorized into five groups,each exhibiting analogous gene structures,featured motifs,and conserved domains.Transcriptome and quantitative real-time PCR analyses revealed that JrLOG gene expression was tissue-specific,developmentally regulated,and responsive to stress situations.Notably,JrLOG3,which localizes to the cell membrane,exhibited high expression levels in leaves and responded to both cold and pathogen infection treatments.This study represents the first comprehensive identification of the LOG gene family in walnut,offering essential data for further functional studies of this gene family.
文摘Literary characters possess a genealogy.Indeed,stock characters like the evil genius or super villain boast family trees that readers can trace not only through time--in this case,starting in the late 19th century--but also across borders.This study traces the genealogical roots of the modern super villain by examining,in turn,Ian Fleming's characters Ernst Blofeld and Dr.Julius No,Sax Rohmer's Dr.Fu Manchu,and Guy Boothby's Dr.Antonio Nikola.In"Orientalism",the author contends that the modern super villain is the embodiment of these writers'orientalist fantasies and fears.Finally,in"Mad Science",the argument is made that the evil geniuses of Fleming,Rohmer,and Boothby may very well be the offspring of an earlier stock character,the mad scientist,who trades monomania for megalomania.
文摘guy是英语口语中较常用的一个单词。一般词典给它的释义大都是a boy或a young man。但是在美国,常会听到一些女学生也相互称呼guys。查一下Dictionary of American Slang,里面确实有a person of either的释义。但以上两种释义都没有对guy一词单数和复数不同的用法加以区别。在实际应用中,guy一词做单数使用时是做a boy或a man 解。
文摘The intrinsic and extrinsic features of the father in The Road as a"Tough Guy"are to be analyzed. For the inner world, heis calm towards the living environments, decisive when faced the emergency and persistent in dignity and morality. For the actions,he is active in seeking foods, brave in fighting with the enemies and gentle with his son. Finally, the conclusion is drawn that the fa-ther is a"Tough Guy".
