Objective: It has been recommended that age-related centile curves of anthropometric indexes(such as height, weight) be used rountinly to evaluate the growth and development statues in children. Presented here is the ...Objective: It has been recommended that age-related centile curves of anthropometric indexes(such as height, weight) be used rountinly to evaluate the growth and development statues in children. Presented here is the age-related height centile curves for children aged 0-18 years in Shaanxi, China,1995. Methods: Data of the Shaanxi population were retrieved from The Third Nationwide Growth Survey to construct the age-related height centile curves. The LMS method was used for curve fitting; all analyses were carried out on the basis of different sexes through a special program for LMS(λ-median-coefficient) method which was devised by Cole TJ. Results: Centile curves for boys and girls, showing similar age-related features but girls'puberty coming two years earlier than boys'. The period of puberty growth increment was about 2 years longer for boys. At age 18, boys were taller than girls for about 14 cm. Compared with height standard of NCHS(national center of health statistics), Shaanxi children were taller than American children before 14 years for boys, 12 years for girls, but after 15 years for boys and 13 years for girls, Shaanxi children were shorter than American ones. At age 18, Shaanxi children was 5.6 cm for boys and 4.9 cm for girls shorter than NCHS. Shaanxi children's height increase range from 1958 to 1995 at the same age was 4.9-15.1 cm ,with the mean of 9.59 cm for boys, and 3.7-12.5 cm, with the mean of 8.38 cm for girls. Between 1958-1995, the increasing velocity every ten years were 2.57 cm for boys and 2.26 cm for girls, which indicated that the children have reached the optimum. Conclusion: By means of LMS method, we constructed age-related height centile curves for Shaanxi children aged 0-18 years, these height centile curves are the first one for the Chinese children. It can be used as a reference for assessing growth and development status of Shaanxi children aged 0-18 years.展开更多
Background:The fetal growth charts in widest use in China were published by Hadlock>35 years ago and were established on data from several hundred of American pregnant women.After that,>100 fetal growth charts w...Background:The fetal growth charts in widest use in China were published by Hadlock>35 years ago and were established on data from several hundred of American pregnant women.After that,>100 fetal growth charts were published around the world.We attempted to assess the impact of applying the long-standing Hadlock charts and other charts in a Chinese population and to compare their ability to predict newborn small for gestational age(SGA).Methods:For this retrospective observational study,we reviewed all pregnant women(n=106,455)who booked prenatal care with ultrasound measurements for fetal biometry at the Shenzhen Maternity and Child Healthcare Hospital between 2012 and 2019.A fractional polynomial regression model was applied to generate Shenzhen fetal growth chart ranges for head circumference(HC),biparietal diameter(BPD),abdominal circumference(AC),and femur length(FL).The differences between Shenzhen charts and published charts were quantified by calculating the Z-score.The impact of applying these published charts was quantifed by calculating the proportions of fetuses with biometric measurements below the 3rd centile of these charts.The sensitivity and area under the receiver operating characteristic curves of published charts to predict neonatal SGA(birthweight<10th centile)were assessed..Results:Following selection,169,980 scans of fetal biometry contributed by 41,032 pregnancies with reliable gestational age were analyzed.When using Hadlock references(<3rd centile),the proportions of small heads and short femurs were as high as 8.9%and 6.6%in late gestation,respectively.The INTERGROWTH-21st standards matched those of our observed curves better than other charts,in particular for fat-free biometry(HC and FL).When using AC<10th centile,all of these references were poor at predicting neonatal SGA.Conclusions:Applying long-standing Hadlock references could misclassify a large proportion of fetuses as SGA.INTERGROWTH-21st standard appears to be a safe option in China.For fat-based biometry,AC,a reference based on the Chinese population is needed.In addition,when applying published charts,particular care should be taken due to the discrepancy of measurement methods.展开更多
文摘Objective: It has been recommended that age-related centile curves of anthropometric indexes(such as height, weight) be used rountinly to evaluate the growth and development statues in children. Presented here is the age-related height centile curves for children aged 0-18 years in Shaanxi, China,1995. Methods: Data of the Shaanxi population were retrieved from The Third Nationwide Growth Survey to construct the age-related height centile curves. The LMS method was used for curve fitting; all analyses were carried out on the basis of different sexes through a special program for LMS(λ-median-coefficient) method which was devised by Cole TJ. Results: Centile curves for boys and girls, showing similar age-related features but girls'puberty coming two years earlier than boys'. The period of puberty growth increment was about 2 years longer for boys. At age 18, boys were taller than girls for about 14 cm. Compared with height standard of NCHS(national center of health statistics), Shaanxi children were taller than American children before 14 years for boys, 12 years for girls, but after 15 years for boys and 13 years for girls, Shaanxi children were shorter than American ones. At age 18, Shaanxi children was 5.6 cm for boys and 4.9 cm for girls shorter than NCHS. Shaanxi children's height increase range from 1958 to 1995 at the same age was 4.9-15.1 cm ,with the mean of 9.59 cm for boys, and 3.7-12.5 cm, with the mean of 8.38 cm for girls. Between 1958-1995, the increasing velocity every ten years were 2.57 cm for boys and 2.26 cm for girls, which indicated that the children have reached the optimum. Conclusion: By means of LMS method, we constructed age-related height centile curves for Shaanxi children aged 0-18 years, these height centile curves are the first one for the Chinese children. It can be used as a reference for assessing growth and development status of Shaanxi children aged 0-18 years.
基金supported by grants from the Shenzhen Science and Technology Project(No.JCYJ20210324130812035)The National Key Research and Development Program of China(No.2018YFC1002200).
文摘Background:The fetal growth charts in widest use in China were published by Hadlock>35 years ago and were established on data from several hundred of American pregnant women.After that,>100 fetal growth charts were published around the world.We attempted to assess the impact of applying the long-standing Hadlock charts and other charts in a Chinese population and to compare their ability to predict newborn small for gestational age(SGA).Methods:For this retrospective observational study,we reviewed all pregnant women(n=106,455)who booked prenatal care with ultrasound measurements for fetal biometry at the Shenzhen Maternity and Child Healthcare Hospital between 2012 and 2019.A fractional polynomial regression model was applied to generate Shenzhen fetal growth chart ranges for head circumference(HC),biparietal diameter(BPD),abdominal circumference(AC),and femur length(FL).The differences between Shenzhen charts and published charts were quantified by calculating the Z-score.The impact of applying these published charts was quantifed by calculating the proportions of fetuses with biometric measurements below the 3rd centile of these charts.The sensitivity and area under the receiver operating characteristic curves of published charts to predict neonatal SGA(birthweight<10th centile)were assessed..Results:Following selection,169,980 scans of fetal biometry contributed by 41,032 pregnancies with reliable gestational age were analyzed.When using Hadlock references(<3rd centile),the proportions of small heads and short femurs were as high as 8.9%and 6.6%in late gestation,respectively.The INTERGROWTH-21st standards matched those of our observed curves better than other charts,in particular for fat-free biometry(HC and FL).When using AC<10th centile,all of these references were poor at predicting neonatal SGA.Conclusions:Applying long-standing Hadlock references could misclassify a large proportion of fetuses as SGA.INTERGROWTH-21st standard appears to be a safe option in China.For fat-based biometry,AC,a reference based on the Chinese population is needed.In addition,when applying published charts,particular care should be taken due to the discrepancy of measurement methods.
