Clarifying the climate change effects on the radial growth of trees has implications for sustainable forest management,especially under global warming.To investigate tree growth responses to regional climate change of...Clarifying the climate change effects on the radial growth of trees has implications for sustainable forest management,especially under global warming.To investigate tree growth responses to regional climate change of Xiaowutai Mountain,four Chinese pine(Pinus tabulaeformis)ring-width index chronologies were established at different elevations(1290–1600 m).Species growth trends were estimated using climate change projections derived from global climate models.The results show:(1)the four ring-width chronologies exhibited strong statistical characteristics,making them suitable for dendroclimatology studies.Radial growth-climate relationships were highly consistent,showing a negative correlation with previous September temperatures and current May–June temperatures,as well as a positively correlated with precipitation and Palmer Drought Severity Index during the corresponding period;and(2)climate change scenarios revealed that temperature will gradually increase on the Xiaowutai Mountain,and only a slight variation in precipitation is expected.Chinese pine radial growth may show a decline under future climate change.展开更多
A morphology-based growth stage system should describe the growth and development of a crop and thereby help farmers and agronomists in formulating reasonable managementmeasures conducive to the development of marketa...A morphology-based growth stage system should describe the growth and development of a crop and thereby help farmers and agronomists in formulating reasonable managementmeasures conducive to the development of marketable products.However,existing growth stage systems for soybean are either based on plant growth or covered particular phases of flower or pod development,making it difficult to use for tracking the entire growth period of individual flowers and pods.Therefore,the first flower and pod,located at the base of the primary raceme in the eighth trifoliate node of the main stem,were chosen to illustrate growth dynamics during the full reproductive period.The size and fresh weight of the primary raceme in the eighth trifoliate leaf axil,the first flower and pod,the pistils in the first flower,and seeds in the first pod were examined,and the growth of these organs was depicted.Integrating the morphological characteristics and growth features of flowers and pods,as well as existing growth stage systems,the growth and development were delineated in 13 stages.In detail,we classified the flower phase based on the relative positions of floral components,inspired by the ratio of bract to flower used for staging,refined the lag phase proposed previously,retained the use of pod length to define the early pod phase,and innovatively described the late pod phase by the seed appearance.The developmental events in each stage of flower and pod were distinctive and closely connected to the corresponding morphology.Taken together,a more detailed growth stage system for describing individual flowers and pods in soybean was established.This system will serve as a valuable research tool for describing the development,gene expression,and cellular metabolism associated with the formation of flowers,pods,and seeds.展开更多
At the Boao Forum for Asia 2025 Annual Conference,the 2025 Annual Report on Asia's Economic Outlook and Integration Process(hereinafter referred to as the Report)was officially released.The report highlights that ...At the Boao Forum for Asia 2025 Annual Conference,the 2025 Annual Report on Asia's Economic Outlook and Integration Process(hereinafter referred to as the Report)was officially released.The report highlights that despite multiple challenges facing global economic recovery,Asia will remain a primary engine of global economic growth.展开更多
Twenty years ago,during an inspection tour of Yucun,a heavily polluted village in Zhejiang Province,Xi Jinping,then secretary of the CPC Zhejiang Provincial Committee,put forward a profound idea:“Lucid waters and lus...Twenty years ago,during an inspection tour of Yucun,a heavily polluted village in Zhejiang Province,Xi Jinping,then secretary of the CPC Zhejiang Provincial Committee,put forward a profound idea:“Lucid waters and lush mountains are invaluable assets.”This insight,now widely known as the“Two Mountains”theory,has since become a cornerstone of Xi Jinping Thought on Ecological Civilisation.It redefined the relationship between economic growth and environmental protection,promoting a model where ecology and economy reinforce one another.展开更多
The tolerance of tree growth to drought in diverse mixed forests subjected to seasonal water shortage is understudied despite their ecological and economic relevance.By combining intra-and inter-annual analyses of rad...The tolerance of tree growth to drought in diverse mixed forests subjected to seasonal water shortage is understudied despite their ecological and economic relevance.By combining intra-and inter-annual analyses of radial growth responses to climate and drought at daily and monthly scales,different strategies to acclimate to hydroclimate variability of coexisting conifers and broadleaves were unveiled.We analyzed the growth patterns and responses to hydroclimate variability in two conifers(Pinus engelmannii,Juniperus deppeana)and two broadleaves(Quercus grisea,Arbutus arizonica)co-occurring in a Madrean pine-oak forest located in NW Mexico.The strongest positive response to daily precipitation was found in the two conifers,but this response peaked earlier in J.deppeana than in P.engelmannii,which presented a more delayed formation of radially-enlarging tracheids.The latest negative response to temperature was found in Q.grisea,which agrees with its more delayed xylogenesis than A.arizonica.P.engelmannii presented the highest responsiveness to water shortage,driven by lower precipitation and high maximum temperatures,responding to longer droughts ending in autumn(r=0.72),whilst A.arizonica showed the lowest responsiveness to short spring droughts(r=0.39).Growth of P.engelmannii was linked to climate-atmospheric circulation patterns over the near Pacific Ocean.Overall,P.engelmannii and A.arizonica showed high growth rates and earlier growth onset,whilst J.deppeana and Q.grisea showed slower growth rates and later growth onset.The Vaganov-Shashkin growth model evidenced that winterspring soil moisture was the key driver of growth.Under more arid conditions and more frequent and hotter droughts,pine stands could rapidly shift towards mixed pine-oak forests.展开更多
Purpose:This study investigates the physics of annual fractional citation growth and its impact on journal bibliographic metrics,focusing on the interplay between journal publication growth and citation dynamics.Desig...Purpose:This study investigates the physics of annual fractional citation growth and its impact on journal bibliographic metrics,focusing on the interplay between journal publication growth and citation dynamics.Design/methodology/approach:We analyze bibliometric data from three prominent fluids journals-Physics of Fluids,Journal of Fluid Mechanics,and Physical Review Fluids-over the period 1999-2023.The analysis examines the relations among annual fractional journal publication growth,citation growth,and bibliographic metric suppressions.Findings:Our findings reveal that the suppression of impact factor growth is significantly influenced by annual fractional journal publication growth rather than citation growth.All three journals exhibit similar responses to publication growth with minimal scatter,following a consistent functional relation.We also identify narrow,nearly Gaussian distributions for annual fractional journal publication growth.Furthermore,we introduce a new growth-independent dimensionless bibliometric metric,journal urgency,the ratio of annual fractional citation growth to the 4-year running average immediacy index.This metric captures effectively the dependency of citation growth on urgency and reveals consistent distributions across the journals analyzed.Research limitations:The study is limited to three major fluids journals and to the availability of bibliometric data from 1999 to 2023.Future work could extend the analysis to other disciplines and journals.Practical implications:Understanding the relation between publication growth and bibliometric suppressions can inform editorial and strategic decisions in journal management.The proposed journal urgency metric offers a novel tool for assessing and comparing journal performance independent of growth rates.Originality/value:This study introduces a new bibliometric metric-journal urgency-that provides fresh insights into citation dynamics and bibliographic metric behavior.It highlights the critical role of publication growth in shaping journal impact factors and CiteScores,offering a unified framework applicable across multiple journals.展开更多
The objective of this study was to determine the optimal proportions of plant growth regulators for growth and non-tube rapid propagation of Cymbidium tortisepalum var. longibracteatum;seedlings were utilized as the m...The objective of this study was to determine the optimal proportions of plant growth regulators for growth and non-tube rapid propagation of Cymbidium tortisepalum var. longibracteatum;seedlings were utilized as the material. The effects of various combinations and concentrations of 6-benzylaminopurine (6-BA), gibberellic acid (GA_(3)), and naphthaleneacetic acid (NAA) on growth and non-tube rapid propagation were assessed through a single-factor testing and response surface methodology. The results indicated that 6-BA at 60 mg/L, GA_(3) at 150 mg/L, and NAA at 30 mg/L were the most effective concentrations for promoting leaf buds formation in the single-factor analysis. Response surface methodology clarified the sensitivity of the proliferation rate of lateral buds to the three factors, with 6-BA being the most influential, followed by GA_(3) and NAA. The increase in leaf area was most significantly influenced by NAA, then GA_(3), and least by 6-BA, while the increase in plant height was most responsive to GA_(3), followed by 6-BA, and then NAA. The ideal concentrations of plant growth regulators were established as 6-BA at 43 mg/L, GA_(3) at 169 mg/L, and NAA at 36 mg/L. Under these conditions, the lateral bud number per plant was 2.78, with a leaf area increment of 2.87 cm2 and a plant height increment of 2.67 cm.展开更多
BACKGROUND Traumatic fractures are mainly caused by various exogenous traumatic events,which not only damage patients’physical health but also affect their psychological state and aggravate stress responses.AIM To an...BACKGROUND Traumatic fractures are mainly caused by various exogenous traumatic events,which not only damage patients’physical health but also affect their psychological state and aggravate stress responses.AIM To analyze the influencing factors of psychological resilience of patients with traumatic fractures and the effect of psychological resilience on posttraumatic growth(PTG).METHODS This study included 188 patients with traumatic fractures admitted to the First People’s Hospital of Shangqiu from November 2022 to November 2023.The participants were categorized based on the patient’s psychological resilience assessed by the Connor-Davidson Resilience Scale(CD-RISC)into the better resilience group(CD-RISC score≥60 points,n=80)and the poor resilience group(CD-RISC score<60 points,n=108).Patients’sleep quality was assessed with the Pittsburgh Sleep Quality Index(PSQI).The identification of the influencing factors of psychological resilience in patients with traumatic fractures was realized by binary Logistic regression(with factors such as sex,age,injury cause,trauma severity,fracture site,personality,and PSQI included for analysis).The determination of the PTG status of all participants used the Chinese version of the Posttraumatic Growth Inventory(C-PTGI).Furthermore,a Spearman correlation analysis was conducted to analyze the association between psychological resilience and PTG.RESULTS The psychological resilience of patients with traumatic fractures was related to age,sex,trauma severity,and personality.The better resilience group demonstrated statistically lower PSQI scores than the poor resilience group(P<0.05).The Logistic regression analysis revealed sex,age,trauma severity,personality,and sleep quality as influencing factors of CD-RISC scores in patients with traumatic fractures(all P<0.05).The score of each C-PTGI dimension and the total score(relating to others,new possibilities,personal strength,spiritual change,and appreciation of life)were higher in the better resilience group than in the poor resilience group(all P<0.05).Spearman correlation analysis indicated a positive association of the CD-RISC score in patients with traumatic fractures with the scores of all dimensions of C-PTGI and the total C-PTGI score(all P<0.05).CONCLUSION The factors influencing the psychological resilience of patients with traumatic fractures include age,sex,trauma severity,personality,and sleep quality,and psychological resilience is closely associated with PTG.展开更多
Epidermal growth factor receptor(EGFR)is one of the most important tyrosine kinase receptor families,which plays a pivotal role in cell signaling transduction and physiological processes.Studies on the EGFR gene in hu...Epidermal growth factor receptor(EGFR)is one of the most important tyrosine kinase receptor families,which plays a pivotal role in cell signaling transduction and physiological processes.Studies on the EGFR gene in humans and other species have demonstrated its pivotal role in regulating the sodium ion balance and mediating sodium and water reabsorption in the kidney's proximal tubules.However,the impact of EGFR gene in how the Yarkand hare(Lepus yarkandensis)adapts to extreme environmental habitat remains unclear,The Yarkand hare is a desert-dwelling animal with multiple adaptations to cope with drought.Given the important physiological function of EGFR gene,we strived to understand its role in arid environment and explore the molecular mechanism of drought tolerance in the Yarkand hare.We first performed segmental cloning of the CDS of the Yarkand hare EGFR gene.Then,We constructed the phylogenetic tree of the Yarkand hare's EGFR gene and compared it with that of other species.The results showed that the Yarkand hare was most closely related to the Tolai hare(Lepus tolai).Through quantitative reverse transcription polymerase chain reaction(RT-qPCR),we discovered that EGFR expression in the kidneys of the Yarkand hare was higher than in the allopatric Tolai hare from non-arid areas.Therefore,we hypothesized that EGFR gene overexpression in the kidney of the Yarkand hare may play a crucial role in drought adaptability.Subsequently,we inserted CDS of EGFR gene into a pcDNA3.1-EGFP expression vector to construct recombinant plasmid,which was transfected into HeLa cells and overexpressed.RT-qPCR demonstrated a notable and statistically significant increase in EGFR mRNA expression and western blot proved stable expression of this protein in HeLa cells.Through cell experiments,EGFR gene overexpression markedly enhanced the survival of Hela cells subjected to NaCl,H_(2)O_(2),and heat stresses,increased superoxide dismutase activity,and decreased malondialdehyde content.In conclusion,these findings preliminarily suggest that EGFR might help the Yarkand hare adapt to extreme environmental conditions.EGFR manipulation in vivo could be a promising strategy to enhance the resilience of animals to extreme conditions.展开更多
Fibroblast growth factor(FGF)signaling encompasses a multitude of functions,including regulation of cell proliferation,differentiation,morphogenesis,and patterning.FGFs and their receptors(FGFR)are crucial for adult t...Fibroblast growth factor(FGF)signaling encompasses a multitude of functions,including regulation of cell proliferation,differentiation,morphogenesis,and patterning.FGFs and their receptors(FGFR)are crucial for adult tissue repair processes.Aberrant FGF signal transduction is associated with various pathological conditions such as cartilage damage,bone loss,muscle reduction,and other core pathological changes observed in orthopedic degenerative diseases like osteoarthritis(OA),intervertebral disc degeneration(IVDD),osteoporosis(OP),and sarcopenia.In OA and IVDD pathologies specifically,FGF1,FGF2,FGF8,FGF9,FGF18,FGF21,and FGF23 regulate the synthesis,catabolism,and ossification of cartilage tissue.Additionally,the dysregulation of FGFR expression(FGFR1 and FGFR3)promotes the pathological process of cartilage degradation.In OP and sarcopenia,endocrine-derived FGFs(FGF19,FGF21,and FGF23)modulate bone mineral synthesis and decomposition as well as muscle tissues.FGF2 and other FGFs also exert regulatory roles.A growing body of research has focused on understanding the implications of FGF signaling in orthopedic degeneration.Moreover,an increasing number of potential targets within the FGF signaling have been identified,such as FGF9,FGF18,and FGF23.However,it should be noted that most of these discoveries are still in the experimental stage,and further studies are needed before clinical application can be considered.Presently,this review aims to document the association between the FGF signaling pathway and the development and progression of orthopedic diseases.Besides,current therapeutic strategies targeting the FGF signaling pathway to prevent and treat orthopedic degeneration will be evaluated.展开更多
Transforming growth factor-beta 1(TGF-β1)has been extensively studied for its pleiotropic effects on central nervous system diseases.The neuroprotective or neurotoxic effects of TGF-β1 in specific brain areas may de...Transforming growth factor-beta 1(TGF-β1)has been extensively studied for its pleiotropic effects on central nervous system diseases.The neuroprotective or neurotoxic effects of TGF-β1 in specific brain areas may depend on the pathological process and cell types involved.Voltage-gated sodium channels(VGSCs)are essential ion channels for the generation of action potentials in neurons,and are involved in various neuroexcitation-related diseases.However,the effects of TGF-β1 on the functional properties of VGSCs and firing properties in cortical neurons remain unclear.In this study,we investigated the effects of TGF-β1 on VGSC function and firing properties in primary cortical neurons from mice.We found that TGF-β1 increased VGSC current density in a dose-and time-dependent manner,which was attributable to the upregulation of Nav1.3 expression.Increased VGSC current density and Nav1.3 expression were significantly abolished by preincubation with inhibitors of mitogen-activated protein kinase kinase(PD98059),p38 mitogen-activated protein kinase(SB203580),and Jun NH2-terminal kinase 1/2 inhibitor(SP600125).Interestingly,TGF-β1 significantly increased the firing threshold of action potentials but did not change their firing rate in cortical neurons.These findings suggest that TGF-β1 can increase Nav1.3 expression through activation of the ERK1/2-JNK-MAPK pathway,which leads to a decrease in the firing threshold of action potentials in cortical neurons under pathological conditions.Thus,this contributes to the occurrence and progression of neuroexcitatory-related diseases of the central nervous system.展开更多
Influenced by complex external factors,the displacement-time curve of reservoir landslides demonstrates both short-term and long-term diversity and dynamic complexity.It is difficult for existing methods,including Reg...Influenced by complex external factors,the displacement-time curve of reservoir landslides demonstrates both short-term and long-term diversity and dynamic complexity.It is difficult for existing methods,including Regression models and Neural network models,to perform multi-characteristic coupled displacement prediction because they fail to consider landslide creep characteristics.This paper integrates the creep characteristics of landslides with non-linear intelligent algorithms and proposes a dynamic intelligent landslide displacement prediction method based on a combination of the Biological Growth model(BG),Convolutional Neural Network(CNN),and Long ShortTerm Memory Network(LSTM).This prediction approach improves three different biological growth models,thereby effectively extracting landslide creep characteristic parameters.Simultaneously,it integrates external factors(rainfall and reservoir water level)to construct an internal and external comprehensive dataset for data augmentation,which is input into the improved CNN-LSTM model.Thereafter,harnessing the robust feature extraction capabilities and spatial translation invariance of CNN,the model autonomously captures short-term local fluctuation characteristics of landslide displacement,and combines LSTM's efficient handling of long-term nonlinear temporal data to improve prediction performance.An evaluation of the Liangshuijing landslide in the Three Gorges Reservoir Area indicates that BG-CNN-LSTM exhibits high prediction accuracy,excellent generalization capabilities when dealing with various types of landslides.The research provides an innovative approach to achieving the whole-process,realtime,high-precision displacement predictions for multicharacteristic coupled landslides.展开更多
The increase in soil temperature associated with climate change has introduced considerable challenges to crop production.Split nitrogen application(SN)represents a potential strategy for improving crop nitrogen use e...The increase in soil temperature associated with climate change has introduced considerable challenges to crop production.Split nitrogen application(SN)represents a potential strategy for improving crop nitrogen use efficiency and enhancing crop stress resistance.Nevertheless,the precise interaction between soil warming(SW)and SN remains unclear.In order to ascertain the impact of SW on maize growth and whether SN can improve the tolerance of maize to SW,a two-year field experiment was conducted(2022-2023).The aim was to examine the influence of two SW ranges(MT,warming 1.40℃;HT,warming 2.75℃)and two nitrogen application methods(N1,one-time basal application of nitrogen fertilizer;N2,one third of base nitrogen fertilizer+two thirds of jointing stage supplemental nitrogen fertilizer)on maize root growth,photosynthetic characteristics,nitrogen use efficiency,and yield.The results demonstrated that SW impeded root growth and precipitated the premature aging of maize leaves following anthesis,particularly in the HT,which led to a notable reduction in maize yield.In comparison to N1,SN has been shown to increase root length density by 8.54%,root bleeding rate by 8.57%,and enhance root distribution ratio in the middle soil layers(20-60 cm).The interaction between SW and SN had a notable impact on maize growth and yield.The SN improved the absorption and utilization efficiency of nitrogen by promoting root development and downward canopy growth,thus improving the tolerance of maize to SW at the later stage of growth.In particular,the N2HT resulted in a 14.51%increase in the photosynthetic rate,a 18.58%increase in nitrogen absorption efficiency,and a 18.32%increase in maize yield compared with N1HT.It can be posited that the SN represents a viable nitrogen management measure with the potential to enhance maize tolerance to soil high-temperature stress.展开更多
Conventional rolled Mg-Al alloy sheets typically exhibit strong basal textures that remain and may even strengthen after recrystallization annealing due to the preferential growth of basal-oriented grains,resulting in...Conventional rolled Mg-Al alloy sheets typically exhibit strong basal textures that remain and may even strengthen after recrystallization annealing due to the preferential growth of basal-oriented grains,resulting in poor formability at room temperature.Therefore,the knowledge of recrystallization and grain growth is critical for modifying textures of Mg-Al alloy sheets.The static recrystallization and texture evolution in a cold-rolled dilute Mg-1Al(wt.%)alloy during various annealed temperatures ranging from 300℃ to 450℃,have been investigated using the quasi in-situ electron backscatter diffraction(EBSD)method.The as-rolled Mg-1Al alloy shows a dominant basal texture,which weakens and broadens in the rolling direction(RD)during the subsequent annealing,accompanied by the formation of{1010}texture component.Particularly,the {1010} texture component is more pronounced after annealing at high temperatures.The quasi in-situ EBSD results show that recrystallized grains are mainly induced by shear bands,which exhibit a wide spectrum of orientations with c-axis tilt angles ranging 20°-45°from the normal direction(ND).Orientations of shear band-induced recrystallized grains are retained during the entire recrystallization process,resulting in a reduction in the texture intensity.Moreover,recrystallized grains belonging to the {1010}texture component grow preferentially compared to those with other orientations,which is attributed to low energy grain boundaries,especially grain boundaries with∼30°misorientation angles.Furthermore,the high temperature annealing facilitates the rapid growth of grain boundaries having a 30°misorientation angle,leading to the occurrence of distinct {1010} texture after annealing at 450℃ for 1 h.The results provide insights for texture modification of rare earth-free low-alloyed Mg alloys by controlling annealing parameters.展开更多
Objectives:This systematic review and meta-analysis aimed to identify and synthesize the factors correlated with posttraumatic growth(PTG)in patients with colorectal cancer(CRC).Methods:PubMed,Web of Science,Embase,Ps...Objectives:This systematic review and meta-analysis aimed to identify and synthesize the factors correlated with posttraumatic growth(PTG)in patients with colorectal cancer(CRC).Methods:PubMed,Web of Science,Embase,PsycINFO,CINAHL,Cochrane Library,China National Knowledge Infrastructure(CNKI),Wanfang database,China Science and Technology Journal Database(VIP)and SinoMed were searched for studies that reported data on the correlated factors associated with PTG in patients with CRC from inception to September 3,2024.The methodological quality of the included studies was assessed via the Agency for Healthcare Research and Quality(AHRQ)methodology checklist and the Newcastle-Ottawa Scale(NOS).Pearson correlation coefficient(r)was utilized to indicate effect size.Meta-analysis was conducted in R Studio.Results:Thirty-one eligible studies encompassing 6,400 participants were included in this review.Correlated factors were identified to be significantly associated with PTG in patients with CRC including demographic factors:residential area(r=0.13),marital status(r=0.10),employment status(r=0.18),education level(r=0.19),income level(r=0.16);disease-related factors:time since surgery(r=0.17),stoma-related complications(r=0.14),health-promoting behavior(r=0.46),and sexual function(r=0.17);psychosocial factors:confrontation coping(r=0.68),avoidance coping(r=-0.65),deliberate rumination(r=0.56),social support(r=0.47),family function(r=0.50),resilience(r=0.53),selfefficacy(r=0.91),self-compassion(r=-0.32),psychosocial adjustment(r=0.39),gratitude(r=0.45),stigma(r=-0.65),self-perceived burden(r=-0.31),fear of cancer recurrence(r=-0.45);and quality of life(r=0.32).Conclusions:This meta-analysis identified 23 factors associated with PTG in CRC patients.Medical workers can combine those relevant factors from the perspective of positive psychology,further explore the occurrence and development mechanism of PTG,and establish targeted interventions to promote PTG.展开更多
Magnesium matrix composites with both high strength and ductility have been achieved by introducing pure Ti particles.However,the properties of the surfaces of the composites need to be improved by surface technology,...Magnesium matrix composites with both high strength and ductility have been achieved by introducing pure Ti particles.However,the properties of the surfaces of the composites need to be improved by surface technology,such as micro-arc oxidation(MAO).In this study,we investigated the influence of the Ti-reinforcement phase on coating growth and evolution by subjecting both AZ91 alloy and AZ91/Ti composite to MAO treatment using silicate-based and phosphate-based electrolytes.Results revealed that the Ti-reinforcement phase influenced the MAO process,altering discharge behavior,and leading to a decreased cell voltage.The vigorous discharge of the Ti-reinforcement phase induced the formation of coating discharge channels,concurrently dissolving and oxidizing Ti-reinforcement to produce a composite ceramic coating with TiO2.The MAO coating on the AZ91/Ti composite exhibited a dark blue macromorphology and distinctive local micromorphological anomalies.In silicate electrolyte,a“volcano-like”localized morphology centered on the discharge channel emerged.In contrast,treatment in phosphate-based electrolyte resulted in a coating morphology similar to typical porous ceramic coatings,with visible radial discharge micropores at the reinforcement phase location.Compared to the AZ91 alloy,the coating on the AZ91/Ti composite exhibited lower thickness and higher porosity.MAO treatment reduced the self-corrosion current density of the AZ91/Ti surface by two orders of magnitude.The silicate coating demonstrated better corrosion resistance than the phosphate coating,attributed to its lower porosity.The formation mechanism of MAO coatings on AZ91/Ti composites in phosphate-based and silicate-based electrolytes was proposed.展开更多
Machine picking in cotton is an emerging practice in India,to solve the problems of labour shortages and production costs increasing.Cotton production has been declining in recent years;however,the high density planti...Machine picking in cotton is an emerging practice in India,to solve the problems of labour shortages and production costs increasing.Cotton production has been declining in recent years;however,the high density planting system(HDPS)offers a viable method to enhance productivity by increasing plant populations per unit area,optimizing resource utilization,and facilitating machine picking.Cotton is an indeterminate plant that produce excessive vegeta-tive growth in favorable soil fertility and moisture conditions,which posing challenges for efficient machine picking.To address this issue,the application of plant growth retardants(PGRs)is essential for controlling canopy architecture.PGRs reduce internode elongation,promote regulated branching,and increase plant compactness,making cotton plants better suited for machine picking.PGRs application also optimizes photosynthates distribution between veg-etative and reproductive growth,resulting in higher yields and improved fibre quality.The integration of HDPS and PGRs applications results in an optimal plant architecture for improving machine picking efficiency.However,the success of this integration is determined by some factors,including cotton variety,environmental conditions,and geographical variations.These approaches not only address yield stagnation and labour shortages but also help to establish more effective and sustainable cotton farming practices,resulting in higher cotton productivity.展开更多
AIM:To assess the relationship between serological parameters and the prognosis of young patients with retinal vein occlusion(RVO)after intravitreal conbercept injection(IVC).METHODS:This study enrolled 100 young pati...AIM:To assess the relationship between serological parameters and the prognosis of young patients with retinal vein occlusion(RVO)after intravitreal conbercept injection(IVC).METHODS:This study enrolled 100 young patients(≤50 years old)diagnosed with RVO-related macular edema(RVO-ME)who had been undergoing IVC at the 474 Hospital in Xinjiang between January 2022 and October 2023.Patients were categorized into two groups:70 eyes in the effective group and 30 eyes in the ineffective group.The effective group comprised patients exhibiting a visual acuity improvement of≥2 lines at the last follow-up,with resolved ME and central macular thickness(CMT)<300μm.Conversely,the ineffective group included patients with visual acuity improvement of<1 line,persistent ME,and CMT≥300μm at the last follow-up.Serological parameters,including white blood cell count,neutrophil count,lymphocyte count,monocyte count,and mean platelet volume were assessed before treatment.The correlation between bestcorrected visual acuity(BCVA)and neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),systemic immune inflammation index(SII),and systemic immune response index(SIRI)was analyzed.Additionally,the association between these serological parameters and the efficacy of IVC was explored.RESULTS:Three months after treatment,the effective group demonstrated a significant improvement in BCVA from 0.82±0.20 to 0.36±0.10,with a concurrent decrease in CMT from 661.28±163.90 to 200.61±82.45μm(P<0.001).Conversely,the ineffective group exhibited minimal changes in BCVA(0.86±0.25 to 0.82±0.14)and CMT(669.84±164.95 to 492.13±138.67μm,P<0.001).The differences in BCVA and CMT between the two groups were statistically significant(P<0.001).According to subgroup analysis,in patients with central RVO(CRVO),BCVA improved from 0.82±0.23 to 0.49±0.12 in the effective group and from 0.80±0.18 to 0.76±0.22 in the ineffective group(P<0.001).The CMT changes followed a similar pattern.In patients with branch RVO(BRVO),comparable trends in BCVA and CMT changes were observed between the effective and ineffective groups(P<0.001).Additionally,the effective group exhibited higher PLR and SII values than the ineffective group(P<0.05).Further CRVO and BRVO subgroups analysis exhibited consistent PLR and SII value trends.CONCLUSION:Compared to other inflammatory factors,elevated PLR and SII levels before treatment are better predictors of outcomes in young RVO-ME patients undergoing IVC treatment.展开更多
基金supported by the National Natural Science Foundation of China(Grant NO.41601198,41701209)the key fund project of Beijing Municipal Research Institute of Eco-Environmental Protection(No.Y2024-002).
文摘Clarifying the climate change effects on the radial growth of trees has implications for sustainable forest management,especially under global warming.To investigate tree growth responses to regional climate change of Xiaowutai Mountain,four Chinese pine(Pinus tabulaeformis)ring-width index chronologies were established at different elevations(1290–1600 m).Species growth trends were estimated using climate change projections derived from global climate models.The results show:(1)the four ring-width chronologies exhibited strong statistical characteristics,making them suitable for dendroclimatology studies.Radial growth-climate relationships were highly consistent,showing a negative correlation with previous September temperatures and current May–June temperatures,as well as a positively correlated with precipitation and Palmer Drought Severity Index during the corresponding period;and(2)climate change scenarios revealed that temperature will gradually increase on the Xiaowutai Mountain,and only a slight variation in precipitation is expected.Chinese pine radial growth may show a decline under future climate change.
基金supported by the National Key Research and Development Program of China(2023YFD2301500).
文摘A morphology-based growth stage system should describe the growth and development of a crop and thereby help farmers and agronomists in formulating reasonable managementmeasures conducive to the development of marketable products.However,existing growth stage systems for soybean are either based on plant growth or covered particular phases of flower or pod development,making it difficult to use for tracking the entire growth period of individual flowers and pods.Therefore,the first flower and pod,located at the base of the primary raceme in the eighth trifoliate node of the main stem,were chosen to illustrate growth dynamics during the full reproductive period.The size and fresh weight of the primary raceme in the eighth trifoliate leaf axil,the first flower and pod,the pistils in the first flower,and seeds in the first pod were examined,and the growth of these organs was depicted.Integrating the morphological characteristics and growth features of flowers and pods,as well as existing growth stage systems,the growth and development were delineated in 13 stages.In detail,we classified the flower phase based on the relative positions of floral components,inspired by the ratio of bract to flower used for staging,refined the lag phase proposed previously,retained the use of pod length to define the early pod phase,and innovatively described the late pod phase by the seed appearance.The developmental events in each stage of flower and pod were distinctive and closely connected to the corresponding morphology.Taken together,a more detailed growth stage system for describing individual flowers and pods in soybean was established.This system will serve as a valuable research tool for describing the development,gene expression,and cellular metabolism associated with the formation of flowers,pods,and seeds.
文摘At the Boao Forum for Asia 2025 Annual Conference,the 2025 Annual Report on Asia's Economic Outlook and Integration Process(hereinafter referred to as the Report)was officially released.The report highlights that despite multiple challenges facing global economic recovery,Asia will remain a primary engine of global economic growth.
文摘Twenty years ago,during an inspection tour of Yucun,a heavily polluted village in Zhejiang Province,Xi Jinping,then secretary of the CPC Zhejiang Provincial Committee,put forward a profound idea:“Lucid waters and lush mountains are invaluable assets.”This insight,now widely known as the“Two Mountains”theory,has since become a cornerstone of Xi Jinping Thought on Ecological Civilisation.It redefined the relationship between economic growth and environmental protection,promoting a model where ecology and economy reinforce one another.
基金funding by the Science and Innovation Ministry(projects PID2021-123675OB-C43 and TED2021-129770B-C21).
文摘The tolerance of tree growth to drought in diverse mixed forests subjected to seasonal water shortage is understudied despite their ecological and economic relevance.By combining intra-and inter-annual analyses of radial growth responses to climate and drought at daily and monthly scales,different strategies to acclimate to hydroclimate variability of coexisting conifers and broadleaves were unveiled.We analyzed the growth patterns and responses to hydroclimate variability in two conifers(Pinus engelmannii,Juniperus deppeana)and two broadleaves(Quercus grisea,Arbutus arizonica)co-occurring in a Madrean pine-oak forest located in NW Mexico.The strongest positive response to daily precipitation was found in the two conifers,but this response peaked earlier in J.deppeana than in P.engelmannii,which presented a more delayed formation of radially-enlarging tracheids.The latest negative response to temperature was found in Q.grisea,which agrees with its more delayed xylogenesis than A.arizonica.P.engelmannii presented the highest responsiveness to water shortage,driven by lower precipitation and high maximum temperatures,responding to longer droughts ending in autumn(r=0.72),whilst A.arizonica showed the lowest responsiveness to short spring droughts(r=0.39).Growth of P.engelmannii was linked to climate-atmospheric circulation patterns over the near Pacific Ocean.Overall,P.engelmannii and A.arizonica showed high growth rates and earlier growth onset,whilst J.deppeana and Q.grisea showed slower growth rates and later growth onset.The Vaganov-Shashkin growth model evidenced that winterspring soil moisture was the key driver of growth.Under more arid conditions and more frequent and hotter droughts,pine stands could rapidly shift towards mixed pine-oak forests.
文摘Purpose:This study investigates the physics of annual fractional citation growth and its impact on journal bibliographic metrics,focusing on the interplay between journal publication growth and citation dynamics.Design/methodology/approach:We analyze bibliometric data from three prominent fluids journals-Physics of Fluids,Journal of Fluid Mechanics,and Physical Review Fluids-over the period 1999-2023.The analysis examines the relations among annual fractional journal publication growth,citation growth,and bibliographic metric suppressions.Findings:Our findings reveal that the suppression of impact factor growth is significantly influenced by annual fractional journal publication growth rather than citation growth.All three journals exhibit similar responses to publication growth with minimal scatter,following a consistent functional relation.We also identify narrow,nearly Gaussian distributions for annual fractional journal publication growth.Furthermore,we introduce a new growth-independent dimensionless bibliometric metric,journal urgency,the ratio of annual fractional citation growth to the 4-year running average immediacy index.This metric captures effectively the dependency of citation growth on urgency and reveals consistent distributions across the journals analyzed.Research limitations:The study is limited to three major fluids journals and to the availability of bibliometric data from 1999 to 2023.Future work could extend the analysis to other disciplines and journals.Practical implications:Understanding the relation between publication growth and bibliometric suppressions can inform editorial and strategic decisions in journal management.The proposed journal urgency metric offers a novel tool for assessing and comparing journal performance independent of growth rates.Originality/value:This study introduces a new bibliometric metric-journal urgency-that provides fresh insights into citation dynamics and bibliographic metric behavior.It highlights the critical role of publication growth in shaping journal impact factors and CiteScores,offering a unified framework applicable across multiple journals.
基金funded by the Sichuan Science and Technology Program“Research on Synergistic Relationship and Reintroduction Technology of C.tortisepalum var.longibracteatum and Endophytic Mycorrhizal Fungi in Eastern Sichuan”(2017JY0132)Longshan Academic Talent Research Supporting Program of SWUST(17LZX521,18LZX522).
文摘The objective of this study was to determine the optimal proportions of plant growth regulators for growth and non-tube rapid propagation of Cymbidium tortisepalum var. longibracteatum;seedlings were utilized as the material. The effects of various combinations and concentrations of 6-benzylaminopurine (6-BA), gibberellic acid (GA_(3)), and naphthaleneacetic acid (NAA) on growth and non-tube rapid propagation were assessed through a single-factor testing and response surface methodology. The results indicated that 6-BA at 60 mg/L, GA_(3) at 150 mg/L, and NAA at 30 mg/L were the most effective concentrations for promoting leaf buds formation in the single-factor analysis. Response surface methodology clarified the sensitivity of the proliferation rate of lateral buds to the three factors, with 6-BA being the most influential, followed by GA_(3) and NAA. The increase in leaf area was most significantly influenced by NAA, then GA_(3), and least by 6-BA, while the increase in plant height was most responsive to GA_(3), followed by 6-BA, and then NAA. The ideal concentrations of plant growth regulators were established as 6-BA at 43 mg/L, GA_(3) at 169 mg/L, and NAA at 36 mg/L. Under these conditions, the lateral bud number per plant was 2.78, with a leaf area increment of 2.87 cm2 and a plant height increment of 2.67 cm.
文摘BACKGROUND Traumatic fractures are mainly caused by various exogenous traumatic events,which not only damage patients’physical health but also affect their psychological state and aggravate stress responses.AIM To analyze the influencing factors of psychological resilience of patients with traumatic fractures and the effect of psychological resilience on posttraumatic growth(PTG).METHODS This study included 188 patients with traumatic fractures admitted to the First People’s Hospital of Shangqiu from November 2022 to November 2023.The participants were categorized based on the patient’s psychological resilience assessed by the Connor-Davidson Resilience Scale(CD-RISC)into the better resilience group(CD-RISC score≥60 points,n=80)and the poor resilience group(CD-RISC score<60 points,n=108).Patients’sleep quality was assessed with the Pittsburgh Sleep Quality Index(PSQI).The identification of the influencing factors of psychological resilience in patients with traumatic fractures was realized by binary Logistic regression(with factors such as sex,age,injury cause,trauma severity,fracture site,personality,and PSQI included for analysis).The determination of the PTG status of all participants used the Chinese version of the Posttraumatic Growth Inventory(C-PTGI).Furthermore,a Spearman correlation analysis was conducted to analyze the association between psychological resilience and PTG.RESULTS The psychological resilience of patients with traumatic fractures was related to age,sex,trauma severity,and personality.The better resilience group demonstrated statistically lower PSQI scores than the poor resilience group(P<0.05).The Logistic regression analysis revealed sex,age,trauma severity,personality,and sleep quality as influencing factors of CD-RISC scores in patients with traumatic fractures(all P<0.05).The score of each C-PTGI dimension and the total score(relating to others,new possibilities,personal strength,spiritual change,and appreciation of life)were higher in the better resilience group than in the poor resilience group(all P<0.05).Spearman correlation analysis indicated a positive association of the CD-RISC score in patients with traumatic fractures with the scores of all dimensions of C-PTGI and the total C-PTGI score(all P<0.05).CONCLUSION The factors influencing the psychological resilience of patients with traumatic fractures include age,sex,trauma severity,personality,and sleep quality,and psychological resilience is closely associated with PTG.
基金supported by the Central Guidance for Local Projects of Xinjiang(ZYYD2024ZY04)the National Natural Science Foundation of China(32260116).
文摘Epidermal growth factor receptor(EGFR)is one of the most important tyrosine kinase receptor families,which plays a pivotal role in cell signaling transduction and physiological processes.Studies on the EGFR gene in humans and other species have demonstrated its pivotal role in regulating the sodium ion balance and mediating sodium and water reabsorption in the kidney's proximal tubules.However,the impact of EGFR gene in how the Yarkand hare(Lepus yarkandensis)adapts to extreme environmental habitat remains unclear,The Yarkand hare is a desert-dwelling animal with multiple adaptations to cope with drought.Given the important physiological function of EGFR gene,we strived to understand its role in arid environment and explore the molecular mechanism of drought tolerance in the Yarkand hare.We first performed segmental cloning of the CDS of the Yarkand hare EGFR gene.Then,We constructed the phylogenetic tree of the Yarkand hare's EGFR gene and compared it with that of other species.The results showed that the Yarkand hare was most closely related to the Tolai hare(Lepus tolai).Through quantitative reverse transcription polymerase chain reaction(RT-qPCR),we discovered that EGFR expression in the kidneys of the Yarkand hare was higher than in the allopatric Tolai hare from non-arid areas.Therefore,we hypothesized that EGFR gene overexpression in the kidney of the Yarkand hare may play a crucial role in drought adaptability.Subsequently,we inserted CDS of EGFR gene into a pcDNA3.1-EGFP expression vector to construct recombinant plasmid,which was transfected into HeLa cells and overexpressed.RT-qPCR demonstrated a notable and statistically significant increase in EGFR mRNA expression and western blot proved stable expression of this protein in HeLa cells.Through cell experiments,EGFR gene overexpression markedly enhanced the survival of Hela cells subjected to NaCl,H_(2)O_(2),and heat stresses,increased superoxide dismutase activity,and decreased malondialdehyde content.In conclusion,these findings preliminarily suggest that EGFR might help the Yarkand hare adapt to extreme environmental conditions.EGFR manipulation in vivo could be a promising strategy to enhance the resilience of animals to extreme conditions.
基金supported by the National Key R&D Program of China(2023YFC3603400)the National Natural Science Foundation of China(82072506,92268115)+2 种基金the Hunan Provincial Science Fund for Distinguished Young Scholars(2024JJ2089)the Science and Technology Innovation Program of Hunan Province(2021RC3025)the National Clinical Research Center for Geriatric Disorders(Xiangya Hospital,2021KF02).
文摘Fibroblast growth factor(FGF)signaling encompasses a multitude of functions,including regulation of cell proliferation,differentiation,morphogenesis,and patterning.FGFs and their receptors(FGFR)are crucial for adult tissue repair processes.Aberrant FGF signal transduction is associated with various pathological conditions such as cartilage damage,bone loss,muscle reduction,and other core pathological changes observed in orthopedic degenerative diseases like osteoarthritis(OA),intervertebral disc degeneration(IVDD),osteoporosis(OP),and sarcopenia.In OA and IVDD pathologies specifically,FGF1,FGF2,FGF8,FGF9,FGF18,FGF21,and FGF23 regulate the synthesis,catabolism,and ossification of cartilage tissue.Additionally,the dysregulation of FGFR expression(FGFR1 and FGFR3)promotes the pathological process of cartilage degradation.In OP and sarcopenia,endocrine-derived FGFs(FGF19,FGF21,and FGF23)modulate bone mineral synthesis and decomposition as well as muscle tissues.FGF2 and other FGFs also exert regulatory roles.A growing body of research has focused on understanding the implications of FGF signaling in orthopedic degeneration.Moreover,an increasing number of potential targets within the FGF signaling have been identified,such as FGF9,FGF18,and FGF23.However,it should be noted that most of these discoveries are still in the experimental stage,and further studies are needed before clinical application can be considered.Presently,this review aims to document the association between the FGF signaling pathway and the development and progression of orthopedic diseases.Besides,current therapeutic strategies targeting the FGF signaling pathway to prevent and treat orthopedic degeneration will be evaluated.
基金supported by the Natural Science Foundation of Guangdong Province,Nos.2019A1515010649(to WC),2022A1515012044(to JS)the China Postdoctoral Science Foundation,No.2018M633091(to JS).
文摘Transforming growth factor-beta 1(TGF-β1)has been extensively studied for its pleiotropic effects on central nervous system diseases.The neuroprotective or neurotoxic effects of TGF-β1 in specific brain areas may depend on the pathological process and cell types involved.Voltage-gated sodium channels(VGSCs)are essential ion channels for the generation of action potentials in neurons,and are involved in various neuroexcitation-related diseases.However,the effects of TGF-β1 on the functional properties of VGSCs and firing properties in cortical neurons remain unclear.In this study,we investigated the effects of TGF-β1 on VGSC function and firing properties in primary cortical neurons from mice.We found that TGF-β1 increased VGSC current density in a dose-and time-dependent manner,which was attributable to the upregulation of Nav1.3 expression.Increased VGSC current density and Nav1.3 expression were significantly abolished by preincubation with inhibitors of mitogen-activated protein kinase kinase(PD98059),p38 mitogen-activated protein kinase(SB203580),and Jun NH2-terminal kinase 1/2 inhibitor(SP600125).Interestingly,TGF-β1 significantly increased the firing threshold of action potentials but did not change their firing rate in cortical neurons.These findings suggest that TGF-β1 can increase Nav1.3 expression through activation of the ERK1/2-JNK-MAPK pathway,which leads to a decrease in the firing threshold of action potentials in cortical neurons under pathological conditions.Thus,this contributes to the occurrence and progression of neuroexcitatory-related diseases of the central nervous system.
基金the funding support from the National Natural Science Foundation of China(Grant No.52308340)Chongqing Talent Innovation and Entrepreneurship Demonstration Team Project(Grant No.cstc2024ycjh-bgzxm0012)the Science and Technology Projects supported by China Coal Technology and Engineering Chongqing Design and Research Institute(Group)Co.,Ltd..(Grant No.H20230317)。
文摘Influenced by complex external factors,the displacement-time curve of reservoir landslides demonstrates both short-term and long-term diversity and dynamic complexity.It is difficult for existing methods,including Regression models and Neural network models,to perform multi-characteristic coupled displacement prediction because they fail to consider landslide creep characteristics.This paper integrates the creep characteristics of landslides with non-linear intelligent algorithms and proposes a dynamic intelligent landslide displacement prediction method based on a combination of the Biological Growth model(BG),Convolutional Neural Network(CNN),and Long ShortTerm Memory Network(LSTM).This prediction approach improves three different biological growth models,thereby effectively extracting landslide creep characteristic parameters.Simultaneously,it integrates external factors(rainfall and reservoir water level)to construct an internal and external comprehensive dataset for data augmentation,which is input into the improved CNN-LSTM model.Thereafter,harnessing the robust feature extraction capabilities and spatial translation invariance of CNN,the model autonomously captures short-term local fluctuation characteristics of landslide displacement,and combines LSTM's efficient handling of long-term nonlinear temporal data to improve prediction performance.An evaluation of the Liangshuijing landslide in the Three Gorges Reservoir Area indicates that BG-CNN-LSTM exhibits high prediction accuracy,excellent generalization capabilities when dealing with various types of landslides.The research provides an innovative approach to achieving the whole-process,realtime,high-precision displacement predictions for multicharacteristic coupled landslides.
基金supported by the Natural Science Fund of China(31771724)the Key Research and Development Project of Shaanxi Province(2024NC-ZDCYL-01-10).
文摘The increase in soil temperature associated with climate change has introduced considerable challenges to crop production.Split nitrogen application(SN)represents a potential strategy for improving crop nitrogen use efficiency and enhancing crop stress resistance.Nevertheless,the precise interaction between soil warming(SW)and SN remains unclear.In order to ascertain the impact of SW on maize growth and whether SN can improve the tolerance of maize to SW,a two-year field experiment was conducted(2022-2023).The aim was to examine the influence of two SW ranges(MT,warming 1.40℃;HT,warming 2.75℃)and two nitrogen application methods(N1,one-time basal application of nitrogen fertilizer;N2,one third of base nitrogen fertilizer+two thirds of jointing stage supplemental nitrogen fertilizer)on maize root growth,photosynthetic characteristics,nitrogen use efficiency,and yield.The results demonstrated that SW impeded root growth and precipitated the premature aging of maize leaves following anthesis,particularly in the HT,which led to a notable reduction in maize yield.In comparison to N1,SN has been shown to increase root length density by 8.54%,root bleeding rate by 8.57%,and enhance root distribution ratio in the middle soil layers(20-60 cm).The interaction between SW and SN had a notable impact on maize growth and yield.The SN improved the absorption and utilization efficiency of nitrogen by promoting root development and downward canopy growth,thus improving the tolerance of maize to SW at the later stage of growth.In particular,the N2HT resulted in a 14.51%increase in the photosynthetic rate,a 18.58%increase in nitrogen absorption efficiency,and a 18.32%increase in maize yield compared with N1HT.It can be posited that the SN represents a viable nitrogen management measure with the potential to enhance maize tolerance to soil high-temperature stress.
基金by National Natural Science Foundation of China(Nos.52271103,52334010 and 52271031)Jilin Scientific and Technological Development Program(Nos.20220301026GX,20210201115GX and 20210301041GX).
文摘Conventional rolled Mg-Al alloy sheets typically exhibit strong basal textures that remain and may even strengthen after recrystallization annealing due to the preferential growth of basal-oriented grains,resulting in poor formability at room temperature.Therefore,the knowledge of recrystallization and grain growth is critical for modifying textures of Mg-Al alloy sheets.The static recrystallization and texture evolution in a cold-rolled dilute Mg-1Al(wt.%)alloy during various annealed temperatures ranging from 300℃ to 450℃,have been investigated using the quasi in-situ electron backscatter diffraction(EBSD)method.The as-rolled Mg-1Al alloy shows a dominant basal texture,which weakens and broadens in the rolling direction(RD)during the subsequent annealing,accompanied by the formation of{1010}texture component.Particularly,the {1010} texture component is more pronounced after annealing at high temperatures.The quasi in-situ EBSD results show that recrystallized grains are mainly induced by shear bands,which exhibit a wide spectrum of orientations with c-axis tilt angles ranging 20°-45°from the normal direction(ND).Orientations of shear band-induced recrystallized grains are retained during the entire recrystallization process,resulting in a reduction in the texture intensity.Moreover,recrystallized grains belonging to the {1010}texture component grow preferentially compared to those with other orientations,which is attributed to low energy grain boundaries,especially grain boundaries with∼30°misorientation angles.Furthermore,the high temperature annealing facilitates the rapid growth of grain boundaries having a 30°misorientation angle,leading to the occurrence of distinct {1010} texture after annealing at 450℃ for 1 h.The results provide insights for texture modification of rare earth-free low-alloyed Mg alloys by controlling annealing parameters.
基金supported by the‘Double First-Class’Construction Specialized Discipline Project at Zhejiang University(No HL2024012).
文摘Objectives:This systematic review and meta-analysis aimed to identify and synthesize the factors correlated with posttraumatic growth(PTG)in patients with colorectal cancer(CRC).Methods:PubMed,Web of Science,Embase,PsycINFO,CINAHL,Cochrane Library,China National Knowledge Infrastructure(CNKI),Wanfang database,China Science and Technology Journal Database(VIP)and SinoMed were searched for studies that reported data on the correlated factors associated with PTG in patients with CRC from inception to September 3,2024.The methodological quality of the included studies was assessed via the Agency for Healthcare Research and Quality(AHRQ)methodology checklist and the Newcastle-Ottawa Scale(NOS).Pearson correlation coefficient(r)was utilized to indicate effect size.Meta-analysis was conducted in R Studio.Results:Thirty-one eligible studies encompassing 6,400 participants were included in this review.Correlated factors were identified to be significantly associated with PTG in patients with CRC including demographic factors:residential area(r=0.13),marital status(r=0.10),employment status(r=0.18),education level(r=0.19),income level(r=0.16);disease-related factors:time since surgery(r=0.17),stoma-related complications(r=0.14),health-promoting behavior(r=0.46),and sexual function(r=0.17);psychosocial factors:confrontation coping(r=0.68),avoidance coping(r=-0.65),deliberate rumination(r=0.56),social support(r=0.47),family function(r=0.50),resilience(r=0.53),selfefficacy(r=0.91),self-compassion(r=-0.32),psychosocial adjustment(r=0.39),gratitude(r=0.45),stigma(r=-0.65),self-perceived burden(r=-0.31),fear of cancer recurrence(r=-0.45);and quality of life(r=0.32).Conclusions:This meta-analysis identified 23 factors associated with PTG in CRC patients.Medical workers can combine those relevant factors from the perspective of positive psychology,further explore the occurrence and development mechanism of PTG,and establish targeted interventions to promote PTG.
基金supported by the Guangdong Major Project of Basic and Applied Basic Research(Grant No.2020B0301030006).
文摘Magnesium matrix composites with both high strength and ductility have been achieved by introducing pure Ti particles.However,the properties of the surfaces of the composites need to be improved by surface technology,such as micro-arc oxidation(MAO).In this study,we investigated the influence of the Ti-reinforcement phase on coating growth and evolution by subjecting both AZ91 alloy and AZ91/Ti composite to MAO treatment using silicate-based and phosphate-based electrolytes.Results revealed that the Ti-reinforcement phase influenced the MAO process,altering discharge behavior,and leading to a decreased cell voltage.The vigorous discharge of the Ti-reinforcement phase induced the formation of coating discharge channels,concurrently dissolving and oxidizing Ti-reinforcement to produce a composite ceramic coating with TiO2.The MAO coating on the AZ91/Ti composite exhibited a dark blue macromorphology and distinctive local micromorphological anomalies.In silicate electrolyte,a“volcano-like”localized morphology centered on the discharge channel emerged.In contrast,treatment in phosphate-based electrolyte resulted in a coating morphology similar to typical porous ceramic coatings,with visible radial discharge micropores at the reinforcement phase location.Compared to the AZ91 alloy,the coating on the AZ91/Ti composite exhibited lower thickness and higher porosity.MAO treatment reduced the self-corrosion current density of the AZ91/Ti surface by two orders of magnitude.The silicate coating demonstrated better corrosion resistance than the phosphate coating,attributed to its lower porosity.The formation mechanism of MAO coatings on AZ91/Ti composites in phosphate-based and silicate-based electrolytes was proposed.
文摘Machine picking in cotton is an emerging practice in India,to solve the problems of labour shortages and production costs increasing.Cotton production has been declining in recent years;however,the high density planting system(HDPS)offers a viable method to enhance productivity by increasing plant populations per unit area,optimizing resource utilization,and facilitating machine picking.Cotton is an indeterminate plant that produce excessive vegeta-tive growth in favorable soil fertility and moisture conditions,which posing challenges for efficient machine picking.To address this issue,the application of plant growth retardants(PGRs)is essential for controlling canopy architecture.PGRs reduce internode elongation,promote regulated branching,and increase plant compactness,making cotton plants better suited for machine picking.PGRs application also optimizes photosynthates distribution between veg-etative and reproductive growth,resulting in higher yields and improved fibre quality.The integration of HDPS and PGRs applications results in an optimal plant architecture for improving machine picking efficiency.However,the success of this integration is determined by some factors,including cotton variety,environmental conditions,and geographical variations.These approaches not only address yield stagnation and labour shortages but also help to establish more effective and sustainable cotton farming practices,resulting in higher cotton productivity.
基金Supported by Youth Cultivation Research Program of Beijing Road Medical Area,Xinjiang Military Region General Hospital,Xinjiang,China(No.2022jzbj105)Science and Technology Program of Urumqi Municipal Health and Wellness Commission(No.202360).
文摘AIM:To assess the relationship between serological parameters and the prognosis of young patients with retinal vein occlusion(RVO)after intravitreal conbercept injection(IVC).METHODS:This study enrolled 100 young patients(≤50 years old)diagnosed with RVO-related macular edema(RVO-ME)who had been undergoing IVC at the 474 Hospital in Xinjiang between January 2022 and October 2023.Patients were categorized into two groups:70 eyes in the effective group and 30 eyes in the ineffective group.The effective group comprised patients exhibiting a visual acuity improvement of≥2 lines at the last follow-up,with resolved ME and central macular thickness(CMT)<300μm.Conversely,the ineffective group included patients with visual acuity improvement of<1 line,persistent ME,and CMT≥300μm at the last follow-up.Serological parameters,including white blood cell count,neutrophil count,lymphocyte count,monocyte count,and mean platelet volume were assessed before treatment.The correlation between bestcorrected visual acuity(BCVA)and neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),systemic immune inflammation index(SII),and systemic immune response index(SIRI)was analyzed.Additionally,the association between these serological parameters and the efficacy of IVC was explored.RESULTS:Three months after treatment,the effective group demonstrated a significant improvement in BCVA from 0.82±0.20 to 0.36±0.10,with a concurrent decrease in CMT from 661.28±163.90 to 200.61±82.45μm(P<0.001).Conversely,the ineffective group exhibited minimal changes in BCVA(0.86±0.25 to 0.82±0.14)and CMT(669.84±164.95 to 492.13±138.67μm,P<0.001).The differences in BCVA and CMT between the two groups were statistically significant(P<0.001).According to subgroup analysis,in patients with central RVO(CRVO),BCVA improved from 0.82±0.23 to 0.49±0.12 in the effective group and from 0.80±0.18 to 0.76±0.22 in the ineffective group(P<0.001).The CMT changes followed a similar pattern.In patients with branch RVO(BRVO),comparable trends in BCVA and CMT changes were observed between the effective and ineffective groups(P<0.001).Additionally,the effective group exhibited higher PLR and SII values than the ineffective group(P<0.05).Further CRVO and BRVO subgroups analysis exhibited consistent PLR and SII value trends.CONCLUSION:Compared to other inflammatory factors,elevated PLR and SII levels before treatment are better predictors of outcomes in young RVO-ME patients undergoing IVC treatment.
