Background The aim of this experiment was to investigate the effect of different levels of betaine(Bet)inclusion in the diet on the intestinal health of growing rabbits under summer heat.A total of 100 weaned Qixing m...Background The aim of this experiment was to investigate the effect of different levels of betaine(Bet)inclusion in the diet on the intestinal health of growing rabbits under summer heat.A total of 100 weaned Qixing meat rabbits aged 35 d with body weight of 748.61±38.59 g were randomly divided into 5 treatment groups:control group(basal diet)and Bet groups(basal diet+0.75,1.0,1.5 or 2.0 g/kg Bet).The average daily temperature in the rabbitry during the experiment was 30.48°C and the relative humidity was 69.44%.Results Dietary addition of Bet had no significant effect on growth performance and health status of growing rabbits(P>0.05),but it increased ileal secretory immunoglobulin A content compared to the control under summer heat(P<0.05).Addition of 0.75 g/kg Bet up-regulated jejunal IL-4,down-regulated ileal TNF-αexpression(P<0.05).The addition of 1.0 g/kg Bet increased the villi height(VH)in the jejunum(P<0.05).Serum glucose levels were reduced,and the expression of SLC6A20 was up-regulated in jejunum and ileum of rabbits fed with 1.5 g/kg Bet(P<0.05).When added at 2.0 g/kg,Bet reduced serum HSP70 content,increased jejunal VH,and up-regulated duodenal SLC7A6,SLC38A2,mTOR and 4EBP-2 expression(P<0.05).Correlation analysis revealed that intestinal mTOR expression was significantly and positively correlated with SLC7A6,SLC38A2,SLC36A1 and IL-4 expression(P<0.05).Conclusions Dietary addition of Bet can up-regulate the expression of anti-inflammatory factors through the AAT/mTOR pathway,improve the intestinal immune function,alleviate intestinal damage in growing rabbits caused by summer heat,and improve intestinal health.展开更多
The investigation was carried out with altogether 332 growing rabbits （ZIKA） in six rounds of 8 weeks duration respectively （R1-R6） with the following occupational objects： wooden gnawing stick （WGS）, plastic g...The investigation was carried out with altogether 332 growing rabbits （ZIKA） in six rounds of 8 weeks duration respectively （R1-R6） with the following occupational objects： wooden gnawing stick （WGS）, plastic gnawing stick （PGS） and two iron chains connected by a horizontal stick （ICS）, wooden gnawing limb （WGL） and a horizontal iron chain （HIC）. The feeding system varied from pellet feeding ad libitum （in the first rounds, in the following rounds it decreased pro-rata whereas the proportion of the crude fibre feed （loose or pressed in blocks） increased appropriately） to crude fibre feeding ad libitum. The behavior ＂occupation with the tool＂ was infrared video recorded and continuously analyzed and summarized in hour-values per rabbit. The average frequency of occupation per rabbit and hour ranged from 0,13 to 2.19 concerning the rounds and between 0.12 and 1,30 concerning the tools. Altogether, it could be assumed that different occupational tools had an influence on the engaging behavior but the effect of the round which was affected by the feeding system was higher. The investigation showed that rabbits spent less time occupying with the tool when they were fed with an increasing percentage of crude fibre （less pellets） in the ration.展开更多
Feed restriction is a common practice to reduce post weaning digestive disorders in rabbits and to get carcasses with less fat. Hydric restriction is commonly used to induce feed restriction in growing rabbits. Two hy...Feed restriction is a common practice to reduce post weaning digestive disorders in rabbits and to get carcasses with less fat. Hydric restriction is commonly used to induce feed restriction in growing rabbits. Two hydric restriction times （2 h and 4 h per day, continuously） were used in our trial carried in good sanitary conditions. Thirty six rabbits were divided at weaning （28 days） into three groups： R2 with restricted access to drinking water from 35 days to 80 days age of 2 h per day （from 8 a.m. to 10 a.m.）, R4： access to drinking water 4 h per day （from 8 a.m. to 12 a.m.） and T （control group） with unlimited access to drinking water. Six animals from each group were slaughtered at 80 days of age. Carcass measurements and meat quality were studied. Histological study for kidneys was carried out. Relative weight of gastrointestinal tract increases with the degree of restriction： 16.5, 18.4 and 18.9 for T, R4 and R2, respectively （P 〈 0.05）. Perirenal fat was lower in restricted groups but differences were not statically significant. Scapular fat decreases of 2/3 or 1/3 respectively with limiting access to drinking water of 2 h or 4 h per day. Compared to control group （T）, meat of restricted groups contains more water： 70.3%, 70% and 69.3% respectively for R4, R2 and T （P 〈 0.01）. The same tendency was observed for proteins： 19.2%, 19.3% and 17.7% for groups R2, R4 and T. Fat decreases in meat of restricted animals： 8.4%, 8.2% and 8.1% respectively for T, R4 and R2 （P 〈 0.05）. Water restriction induced decrease of carcass and meat adiposity. There were no differences between pH post mortem and pH ultimate （after 24 h） between the three groups. Hydric restriction does not effect on kidney histology.展开更多
文摘Background The aim of this experiment was to investigate the effect of different levels of betaine(Bet)inclusion in the diet on the intestinal health of growing rabbits under summer heat.A total of 100 weaned Qixing meat rabbits aged 35 d with body weight of 748.61±38.59 g were randomly divided into 5 treatment groups:control group(basal diet)and Bet groups(basal diet+0.75,1.0,1.5 or 2.0 g/kg Bet).The average daily temperature in the rabbitry during the experiment was 30.48°C and the relative humidity was 69.44%.Results Dietary addition of Bet had no significant effect on growth performance and health status of growing rabbits(P>0.05),but it increased ileal secretory immunoglobulin A content compared to the control under summer heat(P<0.05).Addition of 0.75 g/kg Bet up-regulated jejunal IL-4,down-regulated ileal TNF-αexpression(P<0.05).The addition of 1.0 g/kg Bet increased the villi height(VH)in the jejunum(P<0.05).Serum glucose levels were reduced,and the expression of SLC6A20 was up-regulated in jejunum and ileum of rabbits fed with 1.5 g/kg Bet(P<0.05).When added at 2.0 g/kg,Bet reduced serum HSP70 content,increased jejunal VH,and up-regulated duodenal SLC7A6,SLC38A2,mTOR and 4EBP-2 expression(P<0.05).Correlation analysis revealed that intestinal mTOR expression was significantly and positively correlated with SLC7A6,SLC38A2,SLC36A1 and IL-4 expression(P<0.05).Conclusions Dietary addition of Bet can up-regulate the expression of anti-inflammatory factors through the AAT/mTOR pathway,improve the intestinal immune function,alleviate intestinal damage in growing rabbits caused by summer heat,and improve intestinal health.
文摘The investigation was carried out with altogether 332 growing rabbits （ZIKA） in six rounds of 8 weeks duration respectively （R1-R6） with the following occupational objects： wooden gnawing stick （WGS）, plastic gnawing stick （PGS） and two iron chains connected by a horizontal stick （ICS）, wooden gnawing limb （WGL） and a horizontal iron chain （HIC）. The feeding system varied from pellet feeding ad libitum （in the first rounds, in the following rounds it decreased pro-rata whereas the proportion of the crude fibre feed （loose or pressed in blocks） increased appropriately） to crude fibre feeding ad libitum. The behavior ＂occupation with the tool＂ was infrared video recorded and continuously analyzed and summarized in hour-values per rabbit. The average frequency of occupation per rabbit and hour ranged from 0,13 to 2.19 concerning the rounds and between 0.12 and 1,30 concerning the tools. Altogether, it could be assumed that different occupational tools had an influence on the engaging behavior but the effect of the round which was affected by the feeding system was higher. The investigation showed that rabbits spent less time occupying with the tool when they were fed with an increasing percentage of crude fibre （less pellets） in the ration.
文摘Feed restriction is a common practice to reduce post weaning digestive disorders in rabbits and to get carcasses with less fat. Hydric restriction is commonly used to induce feed restriction in growing rabbits. Two hydric restriction times （2 h and 4 h per day, continuously） were used in our trial carried in good sanitary conditions. Thirty six rabbits were divided at weaning （28 days） into three groups： R2 with restricted access to drinking water from 35 days to 80 days age of 2 h per day （from 8 a.m. to 10 a.m.）, R4： access to drinking water 4 h per day （from 8 a.m. to 12 a.m.） and T （control group） with unlimited access to drinking water. Six animals from each group were slaughtered at 80 days of age. Carcass measurements and meat quality were studied. Histological study for kidneys was carried out. Relative weight of gastrointestinal tract increases with the degree of restriction： 16.5, 18.4 and 18.9 for T, R4 and R2, respectively （P 〈 0.05）. Perirenal fat was lower in restricted groups but differences were not statically significant. Scapular fat decreases of 2/3 or 1/3 respectively with limiting access to drinking water of 2 h or 4 h per day. Compared to control group （T）, meat of restricted groups contains more water： 70.3%, 70% and 69.3% respectively for R4, R2 and T （P 〈 0.01）. The same tendency was observed for proteins： 19.2%, 19.3% and 17.7% for groups R2, R4 and T. Fat decreases in meat of restricted animals： 8.4%, 8.2% and 8.1% respectively for T, R4 and R2 （P 〈 0.05）. Water restriction induced decrease of carcass and meat adiposity. There were no differences between pH post mortem and pH ultimate （after 24 h） between the three groups. Hydric restriction does not effect on kidney histology.
