Whether a decision group does its function or not directly depends on the rationality of its characters. The decision science, also with other correlation disciplines, wants to know how the group characters affect the...Whether a decision group does its function or not directly depends on the rationality of its characters. The decision science, also with other correlation disciplines, wants to know how the group characters affect the group performance. Although there are great deals of means to describe the group characters theoretically and practically, in this paper, we consider that the integrity character of a group is composed of the group scale, the constitution and the structure. So the research on how group characters affect the group performance should focus on the three aspects. In order to grasp the present research situation and clear the prospective direction of the studies, we will summarize the study on how the group characters affect the group performance from these three aspects.展开更多
BACKGROUND Elderly patients with refractory ulcerative colitis(UC)have a poor prognosis,and timely surgical intervention should not be delayed.However,with the advent of biologics,therapy has become more complex,and t...BACKGROUND Elderly patients with refractory ulcerative colitis(UC)have a poor prognosis,and timely surgical intervention should not be delayed.However,with the advent of biologics,therapy has become more complex,and there are no clear criteria for the timing of surgical conversion.AIM To investigate the risk factors for postoperative complications in elderly patients with UC.METHODS Elderly patients(≥60 years old)with refractory UC who underwent colectomy at Hyogo Medical University between April 2012 and March 2024 were included in this study.Fatal complications included life-threatening complications requiring intensive care unit management and death.The primary outcome was defined by possible risk factors for fatal complications in older patients with refractory UC.RESULTS A total of 191 elderly patients with UC were analyzed in this series.The rate of fatal complications was 18/191(9.4%),and the most common complication was pneumonia due to disuse syndrome.Body mass index(BMI)<17 kg/m^(2)[odds ratio(OR)=4.08,95%confidence interval(95%CI):1.19-13.97,P=0.02]and Eastern Cooperative Oncology Group performance status(ECOG-PS)≥3(OR=14.5,95%CI:3.43-61.64,P<0.01)were identified as independent risk factors for fatal complications.CONCLUSION Among the elderly patients with refractory UC,the risk factors for fatal complications were low BMI and ECOG-PS score.Prompt surgical intervention is recommended before the patient loses weight or has difficulty walking.These factors may allow for early surgical decision-making before patients become debilitated.展开更多
Eastern Cooperative Oncology Group(ECOG)performance status and Gleason score are commonly investigated factors for overall survival(OS)in men with castration-resistant prostate cancer(CRPC).However,there is a lack of ...Eastern Cooperative Oncology Group(ECOG)performance status and Gleason score are commonly investigated factors for overall survival(OS)in men with castration-resistant prostate cancer(CRPC).However,there is a lack of consistency regarding their prognostic or predictive value for OS.Therefore,we performed this meta-analysis to assess the associations of ECOG performance status and Gleason score with OS in CRPC patients and compare the two markers in patients under different treatment regimens or with different chemotherapy histories.A systematic literature review of monotherapy studies in CRPC patients was conducted in the PubMed database until May 2019.The data from 8247 patients in 34 studies,including clinical trials and real-world data,were included in our meta-analysis.Of these,twenty studies reported multivariate results and were included in our main analysis.CRPC patients with higher ECOG performance statuses(≥2)had a significantly increased mortality risk than those with lower ECOG performance statuses(<2),hazard ratio(HR):2.10,95%confidence interval(CI):1.68-2.62,and P<0.001.The synthesized HR of OS stratified by Gleason score was 1.01,with a 95%CI of 0.62-1.67(Gleason score≥8 vs<8).Subgroup analysis showed that there was no significant difference in pooled HRs for patients administered taxane chemotherapy(docetaxel and cabazitaxel)and androgen-targeting therapy(abiraterone acetate and enzalutamide)or for patients with different chemotherapy histories.ECOG performance status was identified as a significant prognostic factor in CRPC patients,while Gleason score showed a weak prognostic value for OS based on the available data in our meta-analysis.展开更多
The influence of cells groupings factor to the performance of the cells groupings time-shift pilot scheme is researched for the multiple cells large scale antennas systems（LSAS）. The former researches have confirmed...The influence of cells groupings factor to the performance of the cells groupings time-shift pilot scheme is researched for the multiple cells large scale antennas systems（LSAS）. The former researches have confirmed that the cells groupings time-shift pilots scheme is effective to reduce inter-cell interference, especially pilot contamination, which results from the pilot reuse in adjacent cells. However, they have not specified reasonable cells groupings factor, which plays a critical role in the general performance of the LSAS. Therefore, this problem is researched in details. The time for reverse-link data transmission will be compressed, when the groupings factor surpasses a certain range. Thus it is not always beneficial to increase the cells groupings factor without limitation. Furthermore,a reasonable cells groupings factor is deduced from the perspective of optimization to enhance the system performance. Simulations verify the proposed cell grouping factor.展开更多
Because of the influence of OH groups in phosphate glasses on the radiation of rare-earth ions, the laser performance is degraded. The laser efficiency and the small signal gain experiment of several phosphate glass s...Because of the influence of OH groups in phosphate glasses on the radiation of rare-earth ions, the laser performance is degraded. The laser efficiency and the small signal gain experiment of several phosphate glass samples have been done, the concentration of OH groups in glasses was calculated from the measured absorption coefficient at 3.47 μm. It is shown that the concentration of OH groups in phosphate glasses can seriously influence the laser output characteristics, and the OH groups have worse influence on the laser amplifier than laser oscillator.展开更多
基金This paper is supported by the National Nature Science Foundation （NSF） （No.70371038）, and Excellent Innovative Research Group Funds Project from the NSF of China （No. 70121001）.
文摘Whether a decision group does its function or not directly depends on the rationality of its characters. The decision science, also with other correlation disciplines, wants to know how the group characters affect the group performance. Although there are great deals of means to describe the group characters theoretically and practically, in this paper, we consider that the integrity character of a group is composed of the group scale, the constitution and the structure. So the research on how group characters affect the group performance should focus on the three aspects. In order to grasp the present research situation and clear the prospective direction of the studies, we will summarize the study on how the group characters affect the group performance from these three aspects.
文摘BACKGROUND Elderly patients with refractory ulcerative colitis(UC)have a poor prognosis,and timely surgical intervention should not be delayed.However,with the advent of biologics,therapy has become more complex,and there are no clear criteria for the timing of surgical conversion.AIM To investigate the risk factors for postoperative complications in elderly patients with UC.METHODS Elderly patients(≥60 years old)with refractory UC who underwent colectomy at Hyogo Medical University between April 2012 and March 2024 were included in this study.Fatal complications included life-threatening complications requiring intensive care unit management and death.The primary outcome was defined by possible risk factors for fatal complications in older patients with refractory UC.RESULTS A total of 191 elderly patients with UC were analyzed in this series.The rate of fatal complications was 18/191(9.4%),and the most common complication was pneumonia due to disuse syndrome.Body mass index(BMI)<17 kg/m^(2)[odds ratio(OR)=4.08,95%confidence interval(95%CI):1.19-13.97,P=0.02]and Eastern Cooperative Oncology Group performance status(ECOG-PS)≥3(OR=14.5,95%CI:3.43-61.64,P<0.01)were identified as independent risk factors for fatal complications.CONCLUSION Among the elderly patients with refractory UC,the risk factors for fatal complications were low BMI and ECOG-PS score.Prompt surgical intervention is recommended before the patient loses weight or has difficulty walking.These factors may allow for early surgical decision-making before patients become debilitated.
文摘Eastern Cooperative Oncology Group(ECOG)performance status and Gleason score are commonly investigated factors for overall survival(OS)in men with castration-resistant prostate cancer(CRPC).However,there is a lack of consistency regarding their prognostic or predictive value for OS.Therefore,we performed this meta-analysis to assess the associations of ECOG performance status and Gleason score with OS in CRPC patients and compare the two markers in patients under different treatment regimens or with different chemotherapy histories.A systematic literature review of monotherapy studies in CRPC patients was conducted in the PubMed database until May 2019.The data from 8247 patients in 34 studies,including clinical trials and real-world data,were included in our meta-analysis.Of these,twenty studies reported multivariate results and were included in our main analysis.CRPC patients with higher ECOG performance statuses(≥2)had a significantly increased mortality risk than those with lower ECOG performance statuses(<2),hazard ratio(HR):2.10,95%confidence interval(CI):1.68-2.62,and P<0.001.The synthesized HR of OS stratified by Gleason score was 1.01,with a 95%CI of 0.62-1.67(Gleason score≥8 vs<8).Subgroup analysis showed that there was no significant difference in pooled HRs for patients administered taxane chemotherapy(docetaxel and cabazitaxel)and androgen-targeting therapy(abiraterone acetate and enzalutamide)or for patients with different chemotherapy histories.ECOG performance status was identified as a significant prognostic factor in CRPC patients,while Gleason score showed a weak prognostic value for OS based on the available data in our meta-analysis.
基金supported by the National Natural Science Foundation of China(6110602261574013)
文摘The influence of cells groupings factor to the performance of the cells groupings time-shift pilot scheme is researched for the multiple cells large scale antennas systems（LSAS）. The former researches have confirmed that the cells groupings time-shift pilots scheme is effective to reduce inter-cell interference, especially pilot contamination, which results from the pilot reuse in adjacent cells. However, they have not specified reasonable cells groupings factor, which plays a critical role in the general performance of the LSAS. Therefore, this problem is researched in details. The time for reverse-link data transmission will be compressed, when the groupings factor surpasses a certain range. Thus it is not always beneficial to increase the cells groupings factor without limitation. Furthermore,a reasonable cells groupings factor is deduced from the perspective of optimization to enhance the system performance. Simulations verify the proposed cell grouping factor.
文摘Because of the influence of OH groups in phosphate glasses on the radiation of rare-earth ions, the laser performance is degraded. The laser efficiency and the small signal gain experiment of several phosphate glass samples have been done, the concentration of OH groups in glasses was calculated from the measured absorption coefficient at 3.47 μm. It is shown that the concentration of OH groups in phosphate glasses can seriously influence the laser output characteristics, and the OH groups have worse influence on the laser amplifier than laser oscillator.
